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MCL coexpression mm9:1119

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Phase1 CAGE Peaks

 Short description
Mm9::chr13:56997135..56997154,-p1@Trpc7
Mm9::chr1:16510187..16510214,-p4@Stau2
Mm9::chr4:128798943..128798978,-p2@Hpca
Mm9::chr7:31229598..31229630,-p@chr7:31229598..31229630
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Mm9::chr7:94732627..94732640,+p5@Grm5
Mm9::chr8:111775378..111775391,-p@chr8:111775378..111775391
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Mm9::chrX:22873193..22873235,-p5@Klhl13


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


GO IDGO nameFDR corrected p-value
GO:0001639PLC activating metabotropic glutamate receptor activity0.036972118507159
GO:0047631ADP-ribose diphosphatase activity0.036972118507159



Relative expression of the co-expression cluster over median <br>Analyst:





Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
regional part of nervous system1.58e-3254
neurectoderm1.94e-3264
neural plate1.94e-3264
presumptive neural plate1.94e-3264
neural tube1.14e-3052
neural rod1.14e-3052
future spinal cord1.14e-3052
neural keel1.14e-3052
central nervous system7.83e-3073
nervous system1.67e-2875
ecto-epithelium4.69e-2873
ectoderm-derived structure9.74e-2795
ectoderm9.74e-2795
presumptive ectoderm9.74e-2795
gray matter2.66e-2634
pre-chordal neural plate5.29e-2649
brain2.48e-2547
future brain2.48e-2547
regional part of brain2.12e-2446
anterior neural tube3.21e-2340
regional part of forebrain3.62e-2239
forebrain3.62e-2239
future forebrain3.62e-2239
brain grey matter6.15e-2129
regional part of telencephalon6.15e-2129
telencephalon6.15e-2129
structure with developmental contribution from neural crest4.62e-1992
cerebral cortex2.44e-1321
cerebral hemisphere2.44e-1321
pallium2.44e-1321
regional part of cerebral cortex3.37e-1117
basal ganglion5.15e-098
nuclear complex of neuraxis5.15e-098
aggregate regional part of brain5.15e-098
collection of basal ganglia5.15e-098
cerebral subcortex5.15e-098
occipital lobe7.03e-0910
visual cortex7.03e-0910
neocortex7.03e-0910
posterior neural tube8.70e-0812
chordal neural plate8.70e-0812
spinal cord1.77e-076
dorsal region element1.77e-076
dorsum1.77e-076


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs




JASPAR motifs


Motifs-log10(p-value)

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