MCL coexpression mm9:556

Phase1 CAGE Peaks

	Short description
Mm9::chr11:101329495..101329506,+	p7@Rnd2
Mm9::chr13:25034764..25034799,+	p6@Gpld1
Mm9::chr17:25393219..25393238,-	p1@Baiap3
Mm9::chr18:31476613..31476624,-	p4@Rit2
Mm9::chr1:75274920..75275015,-	p1@Resp18
Mm9::chr1:75275016..75275030,-	p2@Resp18
Mm9::chr3:31106988..31106998,-	p@chr3:31106988..31106998 -
Mm9::chrX:46838265..46838299,+	p@chrX:46838265..46838299 +
Mm9::chrX:47141381..47141413,-	p2@Igsf1
Mm9::chrX:7497036..7497046,+	p2@Pcsk1n
Mm9::chrX:7499517..7499528,-	p@chrX:7499517..7499528 -
Mm9::chrX:7500293..7500317,-	p@chrX:7500293..7500317 -
Mm9::chrX:93908798..93908814,+	p1@Gpr165

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0004621	glycosylphosphatidylinositol phospholipase D activity	0.0170656878321372
GO:0006507	GPI anchor release	0.0170656878321372

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

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Cell Type

Ontology term	p-value	n
CNS neuron (sensu Vertebrata)	1.58e-12	23
neuroblast (sensu Vertebrata)	1.58e-12	23
neuron	4.07e-09	33
neuronal stem cell	4.07e-09	33
neuroblast	4.07e-09	33
electrically signaling cell	4.07e-09	33

Uber Anatomy

Ontology term	p-value	n
regional part of nervous system	1.21e-31	54
neural tube	1.85e-29	52
neural rod	1.85e-29	52
future spinal cord	1.85e-29	52
neural keel	1.85e-29	52
central nervous system	7.11e-29	73
nervous system	1.45e-27	75
neurectoderm	2.05e-27	64
neural plate	2.05e-27	64
presumptive neural plate	2.05e-27	64
brain	1.50e-24	47
future brain	1.50e-24	47
regional part of brain	1.22e-23	46
ecto-epithelium	1.55e-23	73
ectoderm-derived structure	9.51e-23	95
ectoderm	9.51e-23	95
presumptive ectoderm	9.51e-23	95
anterior neural tube	8.88e-22	40
structure with developmental contribution from neural crest	3.42e-21	92
regional part of forebrain	9.41e-21	39
forebrain	9.41e-21	39
future forebrain	9.41e-21	39
pre-chordal neural plate	9.47e-21	49
gray matter	1.45e-17	34
brain grey matter	3.04e-13	29
regional part of telencephalon	3.04e-13	29
telencephalon	3.04e-13	29
occipital lobe	2.28e-09	10
visual cortex	2.28e-09	10
neocortex	2.28e-09	10
diencephalon	8.48e-09	10
future diencephalon	8.48e-09	10
basal ganglion	2.91e-08	8
nuclear complex of neuraxis	2.91e-08	8
aggregate regional part of brain	2.91e-08	8
collection of basal ganglia	2.91e-08	8
cerebral subcortex	2.91e-08	8
posterior neural tube	4.66e-08	12
chordal neural plate	4.66e-08	12
regional part of cerebral cortex	2.41e-07	17
cerebral cortex	3.54e-07	21
cerebral hemisphere	3.54e-07	21
pallium	3.54e-07	21
spinal cord	5.59e-07	6
dorsal region element	5.59e-07	6
dorsum	5.59e-07	6
pituitary gland	7.99e-07	8
gland of diencephalon	7.99e-07	8
neuroendocrine gland	7.99e-07	8

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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