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Coexpression cluster:C1233

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Full id: C1233_cerebellum_occipital_medial_parietal_amygdala_hippocampus_caudate



Phase1 CAGE Peaks

Hg19::chr17:7559761..7559772,+p14@ATP1B2
Hg19::chr20:10287270..10287295,+p@chr20:10287270..10287295
+
Hg19::chr2:149868148..149868166,+p@chr2:149868148..149868166
+
Hg19::chr3:121086468..121086472,+p@chr3:121086468..121086472
+
Hg19::chr5:161277593..161277604,-p@chr5:161277593..161277604
-
Hg19::chr5:36687531..36687542,+p@chr5:36687531..36687542
+
Hg19::chr6:31512638..31512648,-p@chr6:31512638..31512648
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube3.00e-11856
neural rod3.00e-11856
future spinal cord3.00e-11856
neural keel3.00e-11856
regional part of nervous system1.75e-11353
regional part of brain1.75e-11353
regional part of forebrain2.85e-9541
forebrain2.85e-9541
anterior neural tube2.85e-9541
future forebrain2.85e-9541
central nervous system1.72e-9481
brain2.36e-9468
future brain2.36e-9468
nervous system9.88e-9289
brain grey matter5.15e-9034
gray matter5.15e-9034
telencephalon1.55e-8934
cerebral hemisphere2.84e-8332
regional part of telencephalon4.16e-8332
neural plate8.26e-8282
presumptive neural plate8.26e-8282
neurectoderm1.38e-7786
regional part of cerebral cortex3.39e-7522
neocortex7.53e-6820
cerebral cortex7.56e-6625
pallium7.56e-6625
pre-chordal neural plate1.43e-6561
ecto-epithelium1.47e-62104
adult organism7.63e-54114
structure with developmental contribution from neural crest8.14e-50132
ectoderm-derived structure1.41e-45171
ectoderm1.41e-45171
presumptive ectoderm1.41e-45171
organ system subdivision2.77e-34223
tube7.09e-28192
basal ganglion3.44e-259
nuclear complex of neuraxis3.44e-259
aggregate regional part of brain3.44e-259
collection of basal ganglia3.44e-259
cerebral subcortex3.44e-259
neural nucleus7.01e-259
nucleus of brain7.01e-259
posterior neural tube3.32e-2315
chordal neural plate3.32e-2315
gyrus1.09e-226
anatomical conduit2.53e-20240
occipital lobe1.79e-195
temporal lobe3.69e-196
limbic system3.96e-195
parietal lobe7.20e-195
segmental subdivision of hindbrain7.88e-1912
hindbrain7.88e-1912
presumptive hindbrain7.88e-1912
telencephalic nucleus2.93e-187
anatomical cluster2.70e-17373
segmental subdivision of nervous system2.82e-1713
organ part8.64e-16218
corpus striatum3.64e-154
striatum3.64e-154
ventral part of telencephalon3.64e-154
future corpus striatum3.64e-154
regional part of metencephalon6.05e-159
metencephalon6.05e-159
future metencephalon6.05e-159
brainstem8.75e-156
epithelium1.02e-14306
cell layer1.77e-14309
frontal cortex3.62e-123
caudate-putamen4.54e-123
dorsal striatum4.54e-123
multi-tissue structure4.61e-12342
pons1.33e-113
middle temporal gyrus4.53e-092
Ammon's horn6.43e-092
lobe parts of cerebral cortex6.43e-092
hippocampal formation6.43e-092
limbic lobe6.43e-092
amygdala7.80e-092
middle frontal gyrus8.75e-092
diencephalon1.35e-087
future diencephalon1.35e-087
caudate nucleus1.43e-082
future caudate nucleus1.43e-082
locus ceruleus1.80e-082
brainstem nucleus1.80e-082
hindbrain nucleus1.80e-082
dorsal plus ventral thalamus2.09e-082
thalamic complex2.09e-082
organ7.18e-08503
germ layer7.93e-08560
germ layer / neural crest7.93e-08560
embryonic tissue7.93e-08560
presumptive structure7.93e-08560
germ layer / neural crest derived structure7.93e-08560
epiblast (generic)7.93e-08560
embryonic structure1.08e-07564
embryo1.99e-07592
developing anatomical structure3.87e-07581


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.00215847
MA0004.10.502801
MA0006.10.341337
MA0007.10.483857
MA0009.10.973289
MA0014.10.0156227
MA0017.10.380797
MA0019.10.652951
MA0024.10.867125
MA0025.11.10816
MA0027.12.59001
MA0028.10.35747
MA0029.10.886702
MA0030.10.875089
MA0031.10.809638
MA0038.10.60704
MA0040.10.892629
MA0041.10.521615
MA0042.10.48922
MA0043.10.973609
MA0046.10.962263
MA0048.10.120314
MA0050.10.490116
MA0051.10.602745
MA0052.10.896548
MA0055.10.0407081
MA0056.10
MA0057.10.115382
MA0058.10.406232
MA0059.10.404929
MA0060.10.224688
MA0061.10.198335
MA0063.10
MA0066.10.607474
MA0067.11.29359
MA0068.10.162298
MA0069.10.958358
MA0070.10.947018
MA0071.10.567661
MA0072.10.942461
MA0073.11.13289
MA0074.10.60198
MA0076.10.422297
MA0077.10.934645
MA0078.10.703614
MA0081.10.405093
MA0083.10.980893
MA0084.11.48179
MA0087.10.939982
MA0088.10.0723293
MA0089.10
MA0090.11.11391
MA0091.10.505453
MA0092.10.467172
MA0093.10.344385
MA0095.10
MA0098.10
MA0100.10.621149
MA0101.10.347695
MA0103.10.332048
MA0105.10.104569
MA0106.10.648997
MA0107.10.274127
MA0108.20.806528
MA0109.10
MA0111.10.45062
MA0113.10.665691
MA0114.10.269076
MA0115.11.21667
MA0116.10.277571
MA0117.11.01134
MA0119.10.388712
MA0122.11.03753
MA0124.11.17486
MA0125.11.0901
MA0130.10
MA0131.10.722072
MA0132.10
MA0133.10
MA0135.11.00402
MA0136.10.614215
MA0139.10.186511
MA0140.10.564957
MA0141.10.403171
MA0142.10.777365
MA0143.10.66587
MA0144.10.254954
MA0145.10.0807715
MA0146.10.0127148
MA0147.10.281049
MA0148.10.528066
MA0149.10.555119
MA0062.20.193221
MA0035.21.38583
MA0039.20.00276064
MA0138.20.704862
MA0002.20.611548
MA0137.20.95459
MA0104.20.223944
MA0047.20.636643
MA0112.20.262665
MA0065.20.282161
MA0150.10.430951
MA0151.10
MA0152.10.571637
MA0153.11.07307
MA0154.10.102476
MA0155.10.071478
MA0156.10.36627
MA0157.10.749547
MA0158.10
MA0159.10.281681
MA0160.11.34201
MA0161.10
MA0162.10.0249953
MA0163.10.0167306
MA0164.10.678332
MA0080.20.344472
MA0018.20.650405
MA0099.20.572
MA0079.21.2885e-05
MA0102.21.51913
MA0258.10.245543
MA0259.10.289405
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.