FFCP PHASE1:Mm9::chr12:73509649..73509660,-: Difference between revisions
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{{FFCP | {{FFCP|EntrezGene=104001|HGNC=|MCL_coexpression_id=1330|UniProt=Q4FZ95|association_with_transcript=-111bp_to_ENSMUST00000101331_5end|description=CAGE_peak_5_at_Rtn1_5end|id=chr12:73509649..73509660,-|ontology_enrichment_celltype=CL:0000221!2.04e-14!44;CL:0000133!2.04e-14!44;CL:0002319!7.99e-14!43;CL:0000055!1.72e-12!50;CL:0000117!3.52e-12!23;CL:0000337!3.52e-12!23;CL:0000540!2.42e-10!33;CL:0000047!2.42e-10!33;CL:0000031!2.42e-10!33;CL:0000404!2.42e-10!33;CL:0000393!1.17e-09!39;CL:0000211!1.17e-09!39|ontology_enrichment_celltype_v019_2=CL:0000221,2.71e-19,44;CL:0000133,2.71e-19,44;CL:0002319,3.12e-18,43;CL:0000117,3.13e-18,23;CL:0000337,3.13e-18,23;CL:0000540,2.00e-12,33;CL:0000047,2.00e-12,33;CL:0000031,2.00e-12,33;CL:0000404,2.00e-12,33;CL:0000393,7.17e-12,39;CL:0000211,7.17e-12,39;CL:0002321,6.53e-11,70;CL:0002453,4.32e-09,8;CL:0000333,5.33e-07,10;CL:0000095,5.33e-07,10;CL:0000243,5.33e-07,10;CL:0000123,5.33e-07,10;CL:0000125,5.33e-07,10;CL:0000030,5.33e-07,10;CL:0000339,5.33e-07,10|ontology_enrichment_disease=|ontology_enrichment_disease_v019_2=|ontology_enrichment_uberon=UBERON:0001017!2.78e-31!73;UBERON:0005743!2.78e-31!73;UBERON:0000073!3.98e-31!75;UBERON:0001016!3.98e-31!75;UBERON:0004121!3.94e-28!102;UBERON:0000924!3.94e-28!102;UBERON:0006601!3.94e-28!102;UBERON:0000033!6.28e-26!63;UBERON:0001049!5.88e-25!52;UBERON:0005068!5.88e-25!52;UBERON:0006241!5.88e-25!52;UBERON:0007135!5.88e-25!52;UBERON:0002346!2.01e-24!71;UBERON:0003075!2.01e-24!71;UBERON:0007284!2.01e-24!71;UBERON:0000955!7.76e-24!50;UBERON:0006238!7.76e-24!50;UBERON:0002616!4.15e-23!49;UBERON:0003056!8.89e-20!49;UBERON:0002020!1.39e-18!34;UBERON:0003080!5.83e-18!40;UBERON:0002780!3.38e-17!39;UBERON:0001890!3.38e-17!39;UBERON:0006240!3.38e-17!39;UBERON:0002791!1.75e-15!29;UBERON:0003528!1.75e-15!29;UBERON:0001893!1.75e-15!29;UBERON:0007811!6.64e-15!86;UBERON:0000153!1.12e-12!94;UBERON:0000956!9.22e-11!21;UBERON:0001869!9.22e-11!21;UBERON:0000203!9.22e-11!21;UBERON:0002619!4.23e-09!17;UBERON:0000025!5.74e-08!114;UBERON:0004111!9.57e-08!122;UBERON:0003076!1.35e-07!12;UBERON:0003057!1.35e-07!12|ontology_enrichment_uberon_v019_2=UBERON:0001017,7.00e-44,73;UBERON:0001016,2.38e-42,75;UBERON:0004121,6.75e-40,95;UBERON:0000924,6.75e-40,95;UBERON:0006601,6.75e-40,95;UBERON:0000073,3.95e-38,54;UBERON:0001049,2.30e-35,52;UBERON:0005068,2.30e-35,52;UBERON:0006241,2.30e-35,52;UBERON:0007135,2.30e-35,52;UBERON:0002346,8.03e-35,64;UBERON:0003075,8.03e-35,64;UBERON:0007284,8.03e-35,64;UBERON:0010371,9.22e-31,73;UBERON:0000955,4.19e-29,47;UBERON:0006238,4.19e-29,47;UBERON:0002020,5.92e-29,34;UBERON:0002616,8.19e-28,46;UBERON:0010314,3.34e-24,92;UBERON:0003056,1.27e-23,49;UBERON:0003528,5.93e-23,29;UBERON:0002791,5.93e-23,29;UBERON:0001893,5.93e-23,29;UBERON:0003080,7.66e-22,40;UBERON:0002780,1.63e-20,39;UBERON:0001890,1.63e-20,39;UBERON:0006240,1.63e-20,39;UBERON:0002619,1.39e-15,17;UBERON:0003076,1.90e-14,12;UBERON:0003057,1.90e-14,12;UBERON:0000956,5.50e-14,21;UBERON:0001869,5.50e-14,21;UBERON:0000203,5.50e-14,21;UBERON:0000025,9.54e-13,114;UBERON:0004111,4.64e-12,122;UBERON:0002420,1.52e-10,8;UBERON:0007245,1.52e-10,8;UBERON:0010009,1.52e-10,8;UBERON:0010011,1.52e-10,8;UBERON:0000454,1.52e-10,8;UBERON:0002021,5.71e-10,10;UBERON:0000411,5.71e-10,10;UBERON:0001950,5.71e-10,10;UBERON:0011216,6.94e-09,194;UBERON:0002240,8.68e-09,6;UBERON:0005174,8.68e-09,6;UBERON:0001137,8.68e-09,6;UBERON:0001948,2.86e-07,5;UBERON:0002315,2.86e-07,5;UBERON:0004733,3.19e-07,6;UBERON:0004732,3.19e-07,6;UBERON:0002028,3.19e-07,6;UBERON:0007277,3.19e-07,6;UBERON:0000483,4.11e-07,174;UBERON:0001954,4.80e-07,7;UBERON:0003022,4.80e-07,7;UBERON:0002421,4.80e-07,7;UBERON:0000349,4.80e-07,7;UBERON:0002600,4.80e-07,7;UBERON:0000119,6.66e-07,176;UBERON:0002950,7.35e-07,4;UBERON:0001891,7.35e-07,4;UBERON:0009616,7.35e-07,4;UBERON:0010286,7.35e-07,4;UBERON:0000369,9.44e-07,5;UBERON:0002435,9.44e-07,5;UBERON:0000204,9.44e-07,5;UBERON:0010082,9.44e-07,5|phase1_expression=0.480446541314382,0,0.454999239389536,0,0,0,0,0,0.140788722151667,0,0,0,0,0,0,0,0,0,0,0.42438965179803,1.02051948181284,0,0,0,0,0,0,0,0,0,0.221730510655305,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,2.61630187656536,3.73466510648602,8.55491555926847,1.1198913730029,2.87505128729943,0,0,0,1.02903774414379,0.85960031981627,1.03134418455488,2.02316460859598,4.23192783417626,1.90149421051854,0.338844532069132,0.889294796111139,0,0,0,8.38880309451533,10.373894243682,0.622137673850866,0.540023753326763,0.841299845405528,1.99955689082663,3.53389665522582,1.10241719293459,1.15014565221884,0,4.40463523997555,3.95830748064082,4.76180253094355,2.1101806036831,2.01272815925301,1.04182674111352,4.18774498502071,2.8138130501584,3.97275444219706,3.83017161115768,2.84743361598206,2.42319279572891,0.075726193333184,0.226714680320357,0,0,0,0,0,0,0.702222100658759,0,0,0,2.95771181531029,0,0,0,0,0,0,0,0.517875767294343,0.148442139064825,0,0.304465478312141,0.230615497256059,0,0.23517741427141,0,0.247194967734374,0,0,0,0,0,0,7.31951992528868,10.6817820474862,0.766371165625774,0,0,0,5.54225365797844,4.57500602818627,2.01046963380583,6.08385120672968,3.3243009452943,4.77912502486988,4.38051410282946,0,0,0,1.47309299120532,0.130120442962704,0,0.180062129805349,0.753524089178575,1.08858398642125,1.15302348256365,1.12442069471675,2.06962696591213,0,0.189106080167819,0,0,0,0,0,0,0,0,0,0,0,0,0.23674473558521,0,0.154267112887378,0,0.268273401399619,0.116765342367169,0.16455984991348,0,0.0810688095458557,0,0,0,3.99550902271842,2.16099685996497,0,0,0,0.232236671860439,0.128867461322093,0,0,0,0,0.164698954724011,0.251335208800269,0.198956472041151,0,0,0,0,0,0.114248512609729,0,0.203651327845314,0,0.0701358198903186,0,0,0.470996183524124,0,0,0,0.196558995113203,0,0,0,0,0,0.162135226775035,0,0,0,0,0,0,0.482443521363367,0,0.189491411770485,0.325929952884052,0,0.234690248288502,0,0,0.195133647857799,0.157635144106191,0,0.318909537314974,0.327726629431476,0,0.289298117163023,0,0,0.491764273019036,0,5.9403718295483,5.15731421005694,0,0,0.315508219416257,0,0.646270193198397,0,0.445597348164788,0.283076530788832,0,1.46127928955656,0,3.85585579706168,5.25178315270594,0,0.162886959353576,9.23832688646199,0,0,0,0,0,0,0,0,0,0,0,0,1.36175842301515,0.36012218806262,0.388076051348264,0.214337035031592,0,0.535106452806212,0.329098041204242,0.304464949114599,0.23467170806371,0.42366414172764,0,0,0,0,0,0,0.582961673259701,6.67531087237835,0,0,0,0.188368457004691,0,0,0,0,0,0,0.158167996790568,0,0.108005340821801,0,0.218362563746178,0,0.165306911450672,0,0,0,0,0,0,0,0,0,0,0,0,0,0.288030006257865,0,0,0.102710957164827,0,0.179026695667481,0,0.240390899039938,0,0.100966449948148,0,0.100826185136841,0,0,0,0.226730383615211,0,0.0897138566094757,0,0.19318959403219,0.187682475451182,0.73260649706906,0,0,1.6942555278512,1.84130094602871,1.71868654031819,2.23409137046794,3.42541259885321,3.7769694869485,0.675022500231806,2.70192721934532,3.17199686288943,2.5888015587591,0.103787347584177,0.399024873401031,0.512200817262403,0.486213434136588,0.209613162627982,0.551530525350042,0.44449345560323,0.412070114477788,0.320919209591815,0.758091635291392,0.25347929989024,0.943131706930381,0.0936415074698824,0.384150914429216,0.746661096422973,0.476293691283074,0.115884325944855,0.578727661391115,0,0.147198920134397,0.342869252385415,0,0.476872379894642,0,0.282328141245992,0.592302255241736,0.182927972872773,0.789209134313529,0.271608227691724,0,0.593175090620871,0.492522411877817,0.409231043169689,0.77468420592983,0.578719832943424,1.74867404556562,0.233931608445408,0,0.765153328275374,0,0.463735671240843|short_description=p5@Rtn1}} | ||
|EntrezGene=104001 | |||
|HGNC= | |||
|MCL_coexpression_id=1330 | |||
|UniProt=Q4FZ95 | |||
|association_with_transcript=-111bp_to_ENSMUST00000101331_5end | |||
|description=CAGE_peak_5_at_Rtn1_5end | |||
|id=chr12:73509649..73509660,- | |||
|ontology_enrichment_celltype=CL:0000221!2.04e-14!44;CL:0000133!2.04e-14!44;CL:0002319!7.99e-14!43;CL:0000055!1.72e-12!50;CL:0000117!3.52e-12!23;CL:0000337!3.52e-12!23;CL:0000540!2.42e-10!33;CL:0000047!2.42e-10!33;CL:0000031!2.42e-10!33;CL:0000404!2.42e-10!33;CL:0000393!1.17e-09!39;CL:0000211!1.17e-09!39 | |||
|ontology_enrichment_celltype_v019_2=CL:0000221,2.71e-19,44;CL:0000133,2.71e-19,44;CL:0002319,3.12e-18,43;CL:0000117,3.13e-18,23;CL:0000337,3.13e-18,23;CL:0000540,2.00e-12,33;CL:0000047,2.00e-12,33;CL:0000031,2.00e-12,33;CL:0000404,2.00e-12,33;CL:0000393,7.17e-12,39;CL:0000211,7.17e-12,39;CL:0002321,6.53e-11,70;CL:0002453,4.32e-09,8;CL:0000333,5.33e-07,10;CL:0000095,5.33e-07,10;CL:0000243,5.33e-07,10;CL:0000123,5.33e-07,10;CL:0000125,5.33e-07,10;CL:0000030,5.33e-07,10;CL:0000339,5.33e-07,10 | |||
|ontology_enrichment_disease= | |||
|ontology_enrichment_disease_v019_2= | |||
|ontology_enrichment_uberon=UBERON:0001017!2.78e-31!73;UBERON:0005743!2.78e-31!73;UBERON:0000073!3.98e-31!75;UBERON:0001016!3.98e-31!75;UBERON:0004121!3.94e-28!102;UBERON:0000924!3.94e-28!102;UBERON:0006601!3.94e-28!102;UBERON:0000033!6.28e-26!63;UBERON:0001049!5.88e-25!52;UBERON:0005068!5.88e-25!52;UBERON:0006241!5.88e-25!52;UBERON:0007135!5.88e-25!52;UBERON:0002346!2.01e-24!71;UBERON:0003075!2.01e-24!71;UBERON:0007284!2.01e-24!71;UBERON:0000955!7.76e-24!50;UBERON:0006238!7.76e-24!50;UBERON:0002616!4.15e-23!49;UBERON:0003056!8.89e-20!49;UBERON:0002020!1.39e-18!34;UBERON:0003080!5.83e-18!40;UBERON:0002780!3.38e-17!39;UBERON:0001890!3.38e-17!39;UBERON:0006240!3.38e-17!39;UBERON:0002791!1.75e-15!29;UBERON:0003528!1.75e-15!29;UBERON:0001893!1.75e-15!29;UBERON:0007811!6.64e-15!86;UBERON:0000153!1.12e-12!94;UBERON:0000956!9.22e-11!21;UBERON:0001869!9.22e-11!21;UBERON:0000203!9.22e-11!21;UBERON:0002619!4.23e-09!17;UBERON:0000025!5.74e-08!114;UBERON:0004111!9.57e-08!122;UBERON:0003076!1.35e-07!12;UBERON:0003057!1.35e-07!12 | |||
|ontology_enrichment_uberon_v019_2=UBERON:0001017,7.00e-44,73;UBERON:0001016,2.38e-42,75;UBERON:0004121,6.75e-40,95;UBERON:0000924,6.75e-40,95;UBERON:0006601,6.75e-40,95;UBERON:0000073,3.95e-38,54;UBERON:0001049,2.30e-35,52;UBERON:0005068,2.30e-35,52;UBERON:0006241,2.30e-35,52;UBERON:0007135,2.30e-35,52;UBERON:0002346,8.03e-35,64;UBERON:0003075,8.03e-35,64;UBERON:0007284,8.03e-35,64;UBERON:0010371,9.22e-31,73;UBERON:0000955,4.19e-29,47;UBERON:0006238,4.19e-29,47;UBERON:0002020,5.92e-29,34;UBERON:0002616,8.19e-28,46;UBERON:0010314,3.34e-24,92;UBERON:0003056,1.27e-23,49;UBERON:0003528,5.93e-23,29;UBERON:0002791,5.93e-23,29;UBERON:0001893,5.93e-23,29;UBERON:0003080,7.66e-22,40;UBERON:0002780,1.63e-20,39;UBERON:0001890,1.63e-20,39;UBERON:0006240,1.63e-20,39;UBERON:0002619,1.39e-15,17;UBERON:0003076,1.90e-14,12;UBERON:0003057,1.90e-14,12;UBERON:0000956,5.50e-14,21;UBERON:0001869,5.50e-14,21;UBERON:0000203,5.50e-14,21;UBERON:0000025,9.54e-13,114;UBERON:0004111,4.64e-12,122;UBERON:0002420,1.52e-10,8;UBERON:0007245,1.52e-10,8;UBERON:0010009,1.52e-10,8;UBERON:0010011,1.52e-10,8;UBERON:0000454,1.52e-10,8;UBERON:0002021,5.71e-10,10;UBERON:0000411,5.71e-10,10;UBERON:0001950,5.71e-10,10;UBERON:0011216,6.94e-09,194;UBERON:0002240,8.68e-09,6;UBERON:0005174,8.68e-09,6;UBERON:0001137,8.68e-09,6;UBERON:0001948,2.86e-07,5;UBERON:0002315,2.86e-07,5;UBERON:0004733,3.19e-07,6;UBERON:0004732,3.19e-07,6;UBERON:0002028,3.19e-07,6;UBERON:0007277,3.19e-07,6;UBERON:0000483,4.11e-07,174;UBERON:0001954,4.80e-07,7;UBERON:0003022,4.80e-07,7;UBERON:0002421,4.80e-07,7;UBERON:0000349,4.80e-07,7;UBERON:0002600,4.80e-07,7;UBERON:0000119,6.66e-07,176;UBERON:0002950,7.35e-07,4;UBERON:0001891,7.35e-07,4;UBERON:0009616,7.35e-07,4;UBERON:0010286,7.35e-07,4;UBERON:0000369,9.44e-07,5;UBERON:0002435,9.44e-07,5;UBERON:0000204,9.44e-07,5;UBERON:0010082,9.44e-07,5 | |||
|phase1_expression=0.480446541314382,0,0.454999239389536,0,0,0,0,0,0.140788722151667,0,0,0,0,0,0,0,0,0,0,0.42438965179803,1.02051948181284,0,0,0,0,0,0,0,0,0,0.221730510655305,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,2.61630187656536,3.73466510648602,8.55491555926847,1.1198913730029,2.87505128729943,0,0,0,1.02903774414379,0.85960031981627,1.03134418455488,2.02316460859598,4.23192783417626,1.90149421051854,0.338844532069132,0.889294796111139,0,0,0,8.38880309451533,10.373894243682,0.622137673850866,0.540023753326763,0.841299845405528,1.99955689082663,3.53389665522582,1.10241719293459,1.15014565221884,0,4.40463523997555,3.95830748064082,4.76180253094355,2.1101806036831,2.01272815925301,1.04182674111352,4.18774498502071,2.8138130501584,3.97275444219706,3.83017161115768,2.84743361598206,2.42319279572891,0.075726193333184,0.226714680320357,0,0,0,0,0,0,0.702222100658759,0,0,0,2.95771181531029,0,0,0,0,0,0,0,0.517875767294343,0.148442139064825,0,0.304465478312141,0.230615497256059,0,0.23517741427141,0,0.247194967734374,0,0,0,0,0,0,7.31951992528868,10.6817820474862,0.766371165625774,0,0,0,5.54225365797844,4.57500602818627,2.01046963380583,6.08385120672968,3.3243009452943,4.77912502486988,4.38051410282946,0,0,0,1.47309299120532,0.130120442962704,0,0.180062129805349,0.753524089178575,1.08858398642125,1.15302348256365,1.12442069471675,2.06962696591213,0,0.189106080167819,0,0,0,0,0,0,0,0,0,0,0,0,0.23674473558521,0,0.154267112887378,0,0.268273401399619,0.116765342367169,0.16455984991348,0,0.0810688095458557,0,0,0,3.99550902271842,2.16099685996497,0,0,0,0.232236671860439,0.128867461322093,0,0,0,0,0.164698954724011,0.251335208800269,0.198956472041151,0,0,0,0,0,0.114248512609729,0,0.203651327845314,0,0.0701358198903186,0,0,0.470996183524124,0,0,0,0.196558995113203,0,0,0,0,0,0.162135226775035,0,0,0,0,0,0,0.482443521363367,0,0.189491411770485,0.325929952884052,0,0.234690248288502,0,0,0.195133647857799,0.157635144106191,0,0.318909537314974,0.327726629431476,0,0.289298117163023,0,0,0.491764273019036,0,5.9403718295483,5.15731421005694,0,0,0.315508219416257,0,0.646270193198397,0,0.445597348164788,0.283076530788832,0,1.46127928955656,0,3.85585579706168,5.25178315270594,0,0.162886959353576,9.23832688646199,0,0,0,0,0,0,0,0,0,0,0,0,1.36175842301515,0.36012218806262,0.388076051348264,0.214337035031592,0,0.535106452806212,0.329098041204242,0.304464949114599,0.23467170806371,0.42366414172764,0,0,0,0,0,0,0.582961673259701,6.67531087237835,0,0,0,0.188368457004691,0,0,0,0,0,0,0.158167996790568,0,0.108005340821801,0,0.218362563746178,0,0.165306911450672,0,0,0,0,0,0,0,0,0,0,0,0,0,0.288030006257865,0,0,0.102710957164827,0,0.179026695667481,0,0.240390899039938,0,0.100966449948148,0,0.100826185136841,0,0,0,0.226730383615211,0,0.0897138566094757,0,0.19318959403219,0.187682475451182,0.73260649706906,0,0,1.6942555278512,1.84130094602871,1.71868654031819,2.23409137046794,3.42541259885321,3.7769694869485,0.675022500231806,2.70192721934532,3.17199686288943,2.5888015587591,0.103787347584177,0.399024873401031,0.512200817262403,0.486213434136588,0.209613162627982,0.551530525350042,0.44449345560323,0.412070114477788,0.320919209591815,0.758091635291392,0.25347929989024,0.943131706930381,0.0936415074698824,0.384150914429216,0.746661096422973,0.476293691283074,0.115884325944855,0.578727661391115,0,0.147198920134397,0.342869252385415,0,0.476872379894642,0,0.282328141245992,0.592302255241736,0.182927972872773,0.789209134313529,0.271608227691724,0,0.593175090620871,0.492522411877817,0.409231043169689,0.77468420592983,0.578719832943424,1.74867404556562,0.233931608445408,0,0.765153328275374,0,0.463735671240843 | |||
|short_description=p5@Rtn1 | |||
}} |
Revision as of 23:08, 12 September 2013
Short description: | p5@Rtn1 |
---|---|
Species: | Mouse (Mus musculus) |
DPI dataset: | NA |
TSS-like-by-RIKEN-classifier(Yes/No): | NA |
DHS support(Yes/No): | NA |
Description: | CAGE_peak_5_at_Rtn1_5end |
Coexpression cluster: | MCL_coexpression_mm9:1330 |
Association with transcript: | -111bp_to_ENSMUST00000101331_5end |
EntrezGene: | Rtn1 |
Link to Zenbu: | ZENBU |
View on UCSC genome browser
CAGE Expression
- Click each plot point to find sample in table
Ontology-based sample term enrichment analysis<b>Summary:</b>This analysis has been performed by utilizing wilcoxon rank sum test.When the number of associated cells/tissues are > n , randomly sampled n cells/tissues are used for P value calculation with rank sum test. this process are repeated several times, and the P values are averaged on the log space <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source dataset<br>data
Ontology term | p-value | n |
---|---|---|
ectodermal cell | 2.71e-19 | 44 |
neurectodermal cell | 2.71e-19 | 44 |
neural cell | 3.12e-18 | 43 |
CNS neuron (sensu Vertebrata) | 3.13e-18 | 23 |
neuroblast (sensu Vertebrata) | 3.13e-18 | 23 |
neuron | 2.00e-12 | 33 |
neuronal stem cell | 2.00e-12 | 33 |
neuroblast | 2.00e-12 | 33 |
electrically signaling cell | 2.00e-12 | 33 |
electrically responsive cell | 7.17e-12 | 39 |
electrically active cell | 7.17e-12 | 39 |
embryonic cell | 6.53e-11 | 70 |
oligodendrocyte precursor cell | 4.32e-09 | 8 |
migratory neural crest cell | 5.33e-07 | 10 |
neuron associated cell | 5.33e-07 | 10 |
glial cell (sensu Vertebrata) | 5.33e-07 | 10 |
neuron associated cell (sensu Vertebrata) | 5.33e-07 | 10 |
glial cell | 5.33e-07 | 10 |
glioblast | 5.33e-07 | 10 |
glioblast (sensu Vertebrata) | 5.33e-07 | 10 |
Property "Dpi dataset" (as page type) with input value "{{{DPIdataset}}}" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.
Property "TSS like by RIKEN classifier" (as page type) with input value "{{{TSSclassifier}}}" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.
Property "DHS support" (as page type) with input value "{{{DHSsupport}}}" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.