MCL coexpression mm9:3390
From FANTOM5_SSTAR
Phase1 CAGE Peaks
| Short description | |
|---|---|
| Mm9::chr3:125106990..125107049,+ | p1@Ndst4 |
| Mm9::chr5:118291848..118291866,+ | p4@Nos1 |
| Mm9::chr5:118292122..118292176,+ | p3@Nos1 |
Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data
| GO ID | GO name | FDR corrected p-value |
|---|---|---|
| GO:0042737 | drug catabolic process | 0.00488035647693281 |
| GO:0042738 | exogenous drug catabolic process | 0.00488035647693281 |
| GO:0051926 | negative regulation of calcium ion transport | 0.00488035647693281 |
| GO:0004517 | nitric-oxide synthase activity | 0.00488035647693281 |
| GO:0043267 | negative regulation of potassium ion transport | 0.00488035647693281 |
| GO:0002028 | regulation of sodium ion transport | 0.00488035647693281 |
| GO:0043271 | negative regulation of ion transport | 0.00488035647693281 |
| GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity | 0.00488035647693281 |
| GO:0043266 | regulation of potassium ion transport | 0.00488035647693281 |
| GO:0051346 | negative regulation of hydrolase activity | 0.00488035647693281 |
| GO:0017144 | drug metabolic process | 0.00488035647693281 |
| GO:0051924 | regulation of calcium ion transport | 0.00626278096051241 |
| GO:0010181 | FMN binding | 0.00825793342837634 |
| GO:0050661 | NADP binding | 0.00843465802018453 |
| GO:0043269 | regulation of ion transport | 0.00858778011195526 |
| GO:0046209 | nitric oxide metabolic process | 0.0107329601891086 |
| GO:0006809 | nitric oxide biosynthetic process | 0.0107329601891086 |
| GO:0051051 | negative regulation of transport | 0.0107329601891086 |
| GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen | 0.0124262756955159 |
| GO:0042383 | sarcolemma | 0.0146310413010513 |
| GO:0006941 | striated muscle contraction | 0.0146310413010513 |
| GO:0042493 | response to drug | 0.0146310413010513 |
| GO:0008146 | sulfotransferase activity | 0.0205179883055715 |
| GO:0043086 | negative regulation of catalytic activity | 0.0210020079537489 |
| GO:0016782 | transferase activity, transferring sulfur-containing groups | 0.0218754360374072 |
| GO:0050660 | FAD binding | 0.0243281954543166 |
| GO:0044271 | nitrogen compound biosynthetic process | 0.0299979280437709 |
| GO:0003012 | muscle system process | 0.0299979280437709 |
| GO:0006936 | muscle contraction | 0.0299979280437709 |
| GO:0051049 | regulation of transport | 0.0299979280437709 |
| GO:0006816 | calcium ion transport | 0.033305406688356 |
| GO:0005516 | calmodulin binding | 0.033305406688356 |
| GO:0051336 | regulation of hydrolase activity | 0.033305406688356 |
| GO:0020037 | heme binding | 0.033305406688356 |
| GO:0046906 | tetrapyrrole binding | 0.033305406688356 |
| GO:0006814 | sodium ion transport | 0.033305406688356 |
| GO:0050662 | coenzyme binding | 0.0335589023897373 |
| GO:0004497 | monooxygenase activity | 0.0342996321555843 |
| GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | 0.0342996321555843 |
| GO:0015674 | di-, tri-valent inorganic cation transport | 0.0354868763548967 |
| GO:0009055 | electron carrier activity | 0.0354868763548967 |
| GO:0006813 | potassium ion transport | 0.0389539777543435 |
| GO:0048037 | cofactor binding | 0.0417610353083993 |
Relative expression of the co-expression cluster over median <br>Analyst:
Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>
| Ontology term | p-value | n |
|---|---|---|
| neuron | 2.37e-24 | 33 |
| neuronal stem cell | 2.37e-24 | 33 |
| neuroblast | 2.37e-24 | 33 |
| electrically signaling cell | 2.37e-24 | 33 |
| electrically responsive cell | 1.54e-18 | 39 |
| electrically active cell | 1.54e-18 | 39 |
| CNS neuron (sensu Vertebrata) | 3.05e-17 | 23 |
| neuroblast (sensu Vertebrata) | 3.05e-17 | 23 |
| neural cell | 1.87e-16 | 43 |
| ectodermal cell | 8.73e-16 | 44 |
| neurectodermal cell | 8.73e-16 | 44 |
| non-terminally differentiated cell | 6.85e-13 | 49 |
| autonomic neuron | 2.48e-09 | 9 |
TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data
Novel motifs
JASPAR motifs
| Motifs | -log10(p-value) |
|---|---|
|
{{{tfbs_overrepresentation_jaspar}}} |
