FF:10510-107D6: Difference between revisions
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{{f5samples | {{f5samples | ||
|ancestors_in_anatomy_facet=UBERON: | |DRA_sample_Accession=CAGE@SAMD00004684 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL: | |accession_numbers=CAGE;DRX007977;DRR008849;DRZ000274;DRZ001659;DRZ011624;DRZ013009 | ||
| | |ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0001474,UBERON:0002384,UBERON:0000479,UBERON:0000062,UBERON:0000061,UBERON:0000465,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0004765,UBERON:0002204,UBERON:0001434 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000055,CL:0000003,CL:0000548,CL:0002320,CL:0002371,CL:0000255,CL:0000062 | |||
|ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:14566,DOID:201,DOID:0060100,DOID:3347 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100385,FF:0100407 | |||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
|expression_enrichment_score | |||
|fonse_cell_line=FF:0100385 | |fonse_cell_line=FF:0100385 | ||
|fonse_cell_line_closure=FF:0100385 | |fonse_cell_line_closure=FF:0100385 | ||
| Line 35: | Line 41: | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/osteosarcoma%2520cell%2520line%253a143B%252fTK%255e%2528-%2529neo%255e%2528R%2529.CNhs11279.10510-107D6.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/osteosarcoma%2520cell%2520line%253a143B%252fTK%255e%2528-%2529neo%255e%2528R%2529.CNhs11279.10510-107D6.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/osteosarcoma%2520cell%2520line%253a143B%252fTK%255e%2528-%2529neo%255e%2528R%2529.CNhs11279.10510-107D6.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/osteosarcoma%2520cell%2520line%253a143B%252fTK%255e%2528-%2529neo%255e%2528R%2529.CNhs11279.10510-107D6.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/osteosarcoma%2520cell%2520line%253a143B%252fTK%255e%2528-%2529neo%255e%2528R%2529.CNhs11279.10510-107D6.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10510-107D6 | |id=FF:10510-107D6 | ||
|is_a=DOID:3347;;EFO:0002091;;FF: | |is_a=DOID:3347;;EFO:0002091;;FF:0000210;;FF:0100407 | ||
|is_obsolete= | |||
|library_id=CNhs11279 | |||
|library_id_phase_based=2:CNhs11279 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10510 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10510 | |||
|name=osteosarcoma cell line:143B/TK^(-)neo^(R) | |name=osteosarcoma cell line:143B/TK^(-)neo^(R) | ||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
| Line 42: | Line 60: | ||
|profile_cagescan=,,, | |profile_cagescan=,,, | ||
|profile_hcage=CNhs11279,LSID759,release008,COMPLETED | |profile_hcage=CNhs11279,LSID759,release008,COMPLETED | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq=,,, | |profile_srnaseq=,,, | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,-0.160318030086386,0,0.0783425112224267,-0.282403560576942,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.153323010348428,0,0,0,0,0,-0.0979578962680575,0,0,-0.132956589778862,0,0,0,0,0,0,0,0,0,0,0.227979188198738,0,-0.0287949913916175,0,0,0,0,0,0,0,0,0.089774572986535,0,0,0,0.227979188198738,0,0.00176828769235083,0.227979188198738,-0.0969923612426051,0,0,-0.097343627213097,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.270054092728446,0,0,0,0.442430680739327,-0.211197402695869,0,0.227979188198738,0.113989594099369,0,-0.0980353512377064,-0.138477200800895,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.096373593922461,0,0,0,-0.0298469850284923,-0.0489405985623025,0,0,0,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0,-0.0980353512377064,0,0,0.227979188198738,0,0,0,0,0,0.227979188198738,0,0,-0.0191996870868261,0,-0.0973779253364235,-0.143515142523472,0,0,0.0398175565187375,0,0,0,0,0,0,0,0,0,0.0998593212461737,0,-0.0504125515893149,0,0,0,0,0,-0.305472230898407,0,-0.17425806114951,-0.0683442610773682,0,0,0,0,-0.270240669334324,0,0.107099704404998,-0.0827201683234173,0,0.167224704883926,0.145093982037402,0,0,0,-0.013042140729456,0.54863234229342,0,0,-0.121779851751874,0.445224029693524,0,0,0.374811616594597,0,-0.0432417413422538,-0.0286884605922662,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0574934668214365,0.160302501683168,0,0,0,0,0.578001137229856,0,0,-0.145306967757828,0.0259722801187262,0,0.650866470478712,0,-0.302389727009913,0.0549942100182246,0.479776470480956,0.0197516031918381,-0.147401849371139,0.037997468648891,0.0707337728022651,-0.408667584741222,0.241689817374174,-0.0288172818106841,0.27898529765859,0,0.225176090675958,0.0997706312725357,0,0,0.150470261719435,-0.277852688875293,0,0.130701080877127,-0.262135526278035,0.347387785458907,-0.03219018521006,-0.129165774050548,0.304903913452895,-0.0398164901429103,0.715241167213728,-0.457436452896595,0,-0.177926775722631,0.276654864794311,0,0,-0.0504632917905808,-0.298621008745186,0.150030024967552,0,0.0913766426732017,0.15963492712137,0.414660146734374,-0.106350709174067,-0.00134467122627435,0.376708293415585,0,-0.0914861325092754,0,0,0,0,0.376708293415585,0.260896039485411,0.171653405233867,0.14385273186004,0,-0.0648643852411565,0.0497658129255916,0.00505766045457499,0,0.236889489976423,0.174537531804779,0.0786341410542925,0.0572577772545151,0,0.0713730269950288,-0.468682680749375,-0.00819839698213032,-0.422394805391737,0.31826146660376,-0.0193263855116977,0.189444260178212,0.442430680739327,0.519199178597756,0.000673682165096112,1.4537971690205,0.227979188198738,0.0506485363382363,0.178632210653949,0.0325156121563319,0.220955325866714,0,0.317646380828015,0,0.271965738039132,0,-0.304612026182688,0.170711796790793,0.209246234493233,0.0677898779585557,0,0.0896036087645603,-0.788130937773974,0,0,0,0.64853560907392,0.226341210080946,0.270054092728446,-0.211650427864589,0.049364690028598,0,0.359657290846667,0,0,0.0784021697212975,-0.00749684956565036,0,0.298597141740075,-0.0338488097292139,-0.0288619367111123,0.112008114763804,0,0,0.742973340530225,0.145795080946305,0,-0.60592806381803,0.122212813912142,0.550689575084466,0.561113008104955,0.113989594099369,0.268085483961329,0,0,-0.177527765965176,0,0.11731123042615,0,0,-0.135891702499455,0,0,0,0,-0.081276096458395,0,-0.0372432122665722,0,0,0,0,0,0.158605211717083,0.83542995270202,0,0.34475074923463,0,0,0,0,0,0,0,0,0.252990449378605,0,-0.12301741567642,0,0,0,0,-0.215723402553475,-0.203236562094724,0,-0.131862706497632,0,0,0,0,-0.0861409897892114,0,0,0.113989594099369,0,-0.057730457053664,-0.235406740214859,0,0,0,-0.27695440160179,0,0,0,0,-0.0460431681832507,0,0,-0.513998783301865,0,-0.201607742401125,-0.0815818795468414,0,0.238506524311109,-0.627737899015685,0.338668179984775,0,0,-0.0333679435911492,0,0,-0.460590217149065,0,0,0,0,0,0,0,0.227979188198738,0.227979188198738,0.0136646757989827,0,0,0,0,0,0,0,0,0,0,0,-0.0680497128416597,-0.0922240566585104,0,0,0,0,0,0,0,-0.0241060230789031,0.2196431046447,0,0,0,0,0,0,0,0,-0.243446751464504,0,0,0,0,0,-0.0969923612426051,0,0,0,0,-0.564807121153884,0,0,0.750600314294671,0,0,0,0,0,0,0,0,0,0,0,0,0,0.363972012326689,0.0783425112224267,0,0,0,0,0,0,0,-0.27483329820609,0,0,0,0,-0.113884373708977,0,0,0,-0.104796384789156,0,-0.160318030086386,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.113989594099369,0,0,0,0.152095568913053,0,0.00122500682475324,0.086990616915096,0,0,-0.0442742059252493,0,0,0,0,0,0,-0.031340424028527,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.113989594099369,-0.0348580438050884,0,0,0,0,0.376708293415585,0,0,-0.0979578962680575,0,0,0.135946378398212,0,0,0,0,0,0,0.252440241030565,0.155036998813182,0.0345204197598193,0,0,0,0.3528341023134,0.227979188198738,0,0.0206201841555811,0.227979188198738,-0.0667773874189013,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.153323010348428,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0799782308239525,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0800184682686384,0,0,0,0.362267874827139,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0287205735348097,0,0,0,0,0,0,0,0,0.227979188198738,0,0,0,0,-0.0482220752390542,0,0.143602555968711,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.322524854316974,0,0,0,0,-0.0476371106609188,0,0,0,0,0,0,0.227979188198738,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.253610608288505,0,0,0.0586798146926299,0,0,0,0,0,0,0,0,0,0,0,0,-0.0613201791501264,0,0,0,0,0,0,0,0,0,0,0.17954914597307,0,0,0,0,0,0,0,0,1.49659531662789,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0292029648401917,-0.0489405985623025,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.354724076107398,0,0,0,0,0,0,0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| |||
|rna_box=107 | |rna_box=107 | ||
|rna_catalog_number= | |rna_catalog_number= | ||
| Line 57: | Line 78: | ||
|rna_weight_ug=37.586 | |rna_weight_ug=37.586 | ||
|sample_age= | |sample_age= | ||
|sample_category=cell lines | |||
|sample_cell_catalog=RCB0701 | |sample_cell_catalog=RCB0701 | ||
|sample_cell_line=143B/TK^(-)neo^(R) | |sample_cell_line=143B/TK^(-)neo^(R) | ||
| Line 69: | Line 91: | ||
|sample_ethnicity= | |sample_ethnicity= | ||
|sample_experimental_condition= | |sample_experimental_condition= | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;9.70335737622094e-247!GO:0043226;organelle;2.47593421229807e-200!GO:0043229;intracellular organelle;7.00485890521807e-200!GO:0043231;intracellular membrane-bound organelle;3.14366277071792e-191!GO:0043227;membrane-bound organelle;5.34614750002322e-191!GO:0005737;cytoplasm;1.89738919285249e-159!GO:0044422;organelle part;1.14066020429739e-141!GO:0044446;intracellular organelle part;2.09853270976971e-140!GO:0032991;macromolecular complex;8.486588100329e-110!GO:0005634;nucleus;6.78125081671942e-103!GO:0005515;protein binding;1.51747546375205e-96!GO:0044444;cytoplasmic part;1.15126656045486e-94!GO:0044237;cellular metabolic process;2.15126582781284e-93!GO:0044238;primary metabolic process;9.87369742451255e-93!GO:0043170;macromolecule metabolic process;1.08977578911457e-92!GO:0044428;nuclear part;6.05213040146215e-88!GO:0030529;ribonucleoprotein complex;1.30303978749476e-87!GO:0043233;organelle lumen;2.09535740133223e-81!GO:0031974;membrane-enclosed lumen;2.09535740133223e-81!GO:0003723;RNA binding;5.46076229717769e-81!GO:0016043;cellular component organization and biogenesis;2.6012111149659e-65!GO:0043283;biopolymer metabolic process;9.18700357941197e-64!GO:0031981;nuclear lumen;3.03687968250779e-57!GO:0043234;protein complex;6.00027958234148e-57!GO:0010467;gene expression;1.18406291297075e-54!GO:0006396;RNA processing;1.35400398863485e-53!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;8.50194464508535e-53!GO:0005739;mitochondrion;1.21438347493408e-51!GO:0006412;translation;1.1811038839342e-50!GO:0005840;ribosome;2.27597537253603e-50!GO:0019538;protein metabolic process;4.74083498944296e-50!GO:0043228;non-membrane-bound organelle;1.33517304509925e-46!GO:0043232;intracellular non-membrane-bound organelle;1.33517304509925e-46!GO:0044267;cellular protein metabolic process;2.90426605751563e-46!GO:0044260;cellular macromolecule metabolic process;5.1032448443229e-46!GO:0003735;structural constituent of ribosome;1.21148547220288e-43!GO:0006996;organelle organization and biogenesis;1.12650504343573e-42!GO:0016071;mRNA metabolic process;1.69895039000266e-42!GO:0033036;macromolecule localization;5.64155953811902e-42!GO:0015031;protein transport;1.95822148400893e-40!GO:0008380;RNA splicing;2.01230777102555e-39!GO:0006259;DNA metabolic process;6.14620129735124e-39!GO:0033279;ribosomal subunit;7.5127244139562e-39!GO:0045184;establishment of protein localization;1.3839986138904e-37!GO:0008104;protein localization;1.73701464652854e-37!GO:0005654;nucleoplasm;6.12972300113215e-37!GO:0003676;nucleic acid binding;6.70564859976224e-37!GO:0009059;macromolecule biosynthetic process;1.86993192412044e-36!GO:0006397;mRNA processing;2.00365198686347e-36!GO:0031090;organelle membrane;1.00380596518371e-35!GO:0046907;intracellular transport;1.11438454405701e-35!GO:0044429;mitochondrial part;1.97980090913951e-34!GO:0031967;organelle envelope;1.23512730560031e-33!GO:0031975;envelope;1.54025794321122e-33!GO:0044249;cellular biosynthetic process;1.63236711904794e-33!GO:0000166;nucleotide binding;1.62456271329737e-32!GO:0005829;cytosol;3.07993160653751e-32!GO:0022613;ribonucleoprotein complex biogenesis and assembly;4.85808111514715e-32!GO:0009058;biosynthetic process;7.92338812359254e-32!GO:0065003;macromolecular complex assembly;2.42029022688382e-31!GO:0044451;nucleoplasm part;5.96623853494156e-31!GO:0005830;cytosolic ribosome (sensu Eukaryota);7.93805998795903e-29!GO:0006886;intracellular protein transport;8.57482299024935e-29!GO:0005681;spliceosome;7.55802253272026e-28!GO:0022607;cellular component assembly;1.17635807243663e-27!GO:0016070;RNA metabolic process;2.29450682839847e-27!GO:0007049;cell cycle;1.03929654276246e-26!GO:0051649;establishment of cellular localization;2.40930866915503e-24!GO:0051641;cellular localization;2.89608213157803e-24!GO:0006366;transcription from RNA polymerase II promoter;3.27930157671127e-23!GO:0044445;cytosolic part;6.28174723568138e-23!GO:0032553;ribonucleotide binding;1.63238046114578e-22!GO:0032555;purine ribonucleotide binding;1.63238046114578e-22!GO:0005730;nucleolus;1.83828604200101e-22!GO:0051276;chromosome organization and biogenesis;3.51693052989553e-22!GO:0008134;transcription factor binding;5.31938413741533e-22!GO:0005694;chromosome;6.77487739821576e-22!GO:0017076;purine nucleotide binding;8.16803747603829e-22!GO:0005740;mitochondrial envelope;1.85018259959196e-21!GO:0005524;ATP binding;5.68208890436577e-21!GO:0016462;pyrophosphatase activity;5.71652483609587e-21!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;8.37944390634858e-21!GO:0017111;nucleoside-triphosphatase activity;1.04397406442865e-20!GO:0019866;organelle inner membrane;1.29015367589112e-20!GO:0032559;adenyl ribonucleotide binding;1.37086923388669e-20!GO:0016817;hydrolase activity, acting on acid anhydrides;1.55986301396506e-20!GO:0031966;mitochondrial membrane;1.87808657735429e-20!GO:0015934;large ribosomal subunit;2.55739598325368e-20!GO:0006457;protein folding;9.51615543545993e-20!GO:0015935;small ribosomal subunit;1.21103262715661e-19!GO:0030554;adenyl nucleotide binding;1.23651467867069e-19!GO:0006119;oxidative phosphorylation;2.39136422343212e-19!GO:0006325;establishment and/or maintenance of chromatin architecture;3.12214554101063e-19!GO:0005743;mitochondrial inner membrane;6.86052165732234e-19!GO:0022618;protein-RNA complex assembly;1.03003016143499e-18!GO:0022402;cell cycle process;1.47467943150738e-18!GO:0044427;chromosomal part;1.52960845370582e-18!GO:0006323;DNA packaging;1.89071266664926e-18!GO:0016874;ligase activity;2.43779683140394e-18!GO:0043285;biopolymer catabolic process;2.50498505804574e-18!GO:0006512;ubiquitin cycle;3.74357724664996e-18!GO:0043412;biopolymer modification;4.32515756146274e-18!GO:0051603;proteolysis involved in cellular protein catabolic process;4.40757332672451e-18!GO:0019941;modification-dependent protein catabolic process;4.95282055815309e-18!GO:0043632;modification-dependent macromolecule catabolic process;4.95282055815309e-18!GO:0006511;ubiquitin-dependent protein catabolic process;9.20992535749124e-18!GO:0044257;cellular protein catabolic process;1.37716085172558e-17!GO:0000278;mitotic cell cycle;2.35487017140481e-17!GO:0044265;cellular macromolecule catabolic process;3.33270750402277e-17!GO:0006974;response to DNA damage stimulus;1.00586941373866e-16!GO:0044455;mitochondrial membrane part;1.08733589456874e-16!GO:0031980;mitochondrial lumen;2.37159640111787e-16!GO:0005759;mitochondrial matrix;2.37159640111787e-16!GO:0008135;translation factor activity, nucleic acid binding;2.68201267053418e-16!GO:0030163;protein catabolic process;7.50568598225141e-16!GO:0006464;protein modification process;8.97319493809793e-16!GO:0009057;macromolecule catabolic process;9.70175107061258e-16!GO:0006605;protein targeting;1.07642161959727e-15!GO:0016604;nuclear body;5.08008085016221e-15!GO:0004386;helicase activity;6.6946089369762e-15!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);6.69961058773952e-15!GO:0012505;endomembrane system;7.65440250236231e-15!GO:0051082;unfolded protein binding;9.72002815137253e-15!GO:0003712;transcription cofactor activity;1.26404309269974e-14!GO:0000398;nuclear mRNA splicing, via spliceosome;1.34164590336116e-14!GO:0000375;RNA splicing, via transesterification reactions;1.34164590336116e-14!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.34164590336116e-14!GO:0016887;ATPase activity;1.76219274949365e-14!GO:0043687;post-translational protein modification;1.8893021789548e-14!GO:0042254;ribosome biogenesis and assembly;1.98585233663106e-14!GO:0006281;DNA repair;2.5845423066801e-14!GO:0050794;regulation of cellular process;3.82847926492073e-14!GO:0042623;ATPase activity, coupled;3.89501092926941e-14!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);5.0370113806767e-14!GO:0048523;negative regulation of cellular process;5.08604067255746e-14!GO:0006357;regulation of transcription from RNA polymerase II promoter;6.04002540787787e-14!GO:0005746;mitochondrial respiratory chain;6.37569450226495e-14!GO:0006333;chromatin assembly or disassembly;1.13108741223898e-13!GO:0000785;chromatin;1.1345687177149e-13!GO:0051301;cell division;1.37129708970323e-13!GO:0005761;mitochondrial ribosome;1.98310059120448e-13!GO:0000313;organellar ribosome;1.98310059120448e-13!GO:0006260;DNA replication;2.16628691262703e-13!GO:0005794;Golgi apparatus;2.45127088739065e-13!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;2.52595092788263e-13!GO:0050136;NADH dehydrogenase (quinone) activity;3.11836526566511e-13!GO:0003954;NADH dehydrogenase activity;3.11836526566511e-13!GO:0008137;NADH dehydrogenase (ubiquinone) activity;3.11836526566511e-13!GO:0008026;ATP-dependent helicase activity;4.14140787059991e-13!GO:0048193;Golgi vesicle transport;4.87392331896827e-13!GO:0048770;pigment granule;4.97990453495707e-13!GO:0042470;melanosome;4.97990453495707e-13!GO:0005635;nuclear envelope;6.36766894958968e-13!GO:0000087;M phase of mitotic cell cycle;9.15262991043826e-13!GO:0006913;nucleocytoplasmic transport;1.48136815083519e-12!GO:0007067;mitosis;2.2021481583629e-12!GO:0051169;nuclear transport;2.24446083561648e-12!GO:0048519;negative regulation of biological process;2.56916605485642e-12!GO:0031965;nuclear membrane;3.75308420959377e-12!GO:0016192;vesicle-mediated transport;4.08637827491514e-12!GO:0003743;translation initiation factor activity;4.19071542131118e-12!GO:0000502;proteasome complex (sensu Eukaryota);4.8480065396495e-12!GO:0044248;cellular catabolic process;5.98420932593282e-12!GO:0016607;nuclear speck;6.65971198758238e-12!GO:0016568;chromatin modification;8.31525678329802e-12!GO:0012501;programmed cell death;9.35639892556688e-12!GO:0044453;nuclear membrane part;1.33426085622051e-11!GO:0009719;response to endogenous stimulus;1.37007071313948e-11!GO:0042775;organelle ATP synthesis coupled electron transport;1.86136314760942e-11!GO:0042773;ATP synthesis coupled electron transport;1.86136314760942e-11!GO:0006915;apoptosis;1.98149309616365e-11!GO:0022403;cell cycle phase;2.17640956769861e-11!GO:0008639;small protein conjugating enzyme activity;2.90082013545943e-11!GO:0005667;transcription factor complex;3.12094201675809e-11!GO:0030964;NADH dehydrogenase complex (quinone);3.20003591947951e-11!GO:0045271;respiratory chain complex I;3.20003591947951e-11!GO:0005747;mitochondrial respiratory chain complex I;3.20003591947951e-11!GO:0050789;regulation of biological process;8.81542982466082e-11!GO:0051726;regulation of cell cycle;8.81542982466082e-11!GO:0006413;translational initiation;8.95073224412831e-11!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;9.45360764853838e-11!GO:0004842;ubiquitin-protein ligase activity;9.53759293803076e-11!GO:0016563;transcription activator activity;1.01862885510398e-10!GO:0008219;cell death;1.32980270896421e-10!GO:0016265;death;1.32980270896421e-10!GO:0006403;RNA localization;1.51830253197593e-10!GO:0006446;regulation of translational initiation;1.62020340204652e-10!GO:0000074;regulation of progression through cell cycle;1.67730925200653e-10!GO:0019787;small conjugating protein ligase activity;1.91492493057031e-10!GO:0050657;nucleic acid transport;1.91492493057031e-10!GO:0051236;establishment of RNA localization;1.91492493057031e-10!GO:0050658;RNA transport;1.91492493057031e-10!GO:0016879;ligase activity, forming carbon-nitrogen bonds;2.36653035882411e-10!GO:0017038;protein import;2.66724666719368e-10!GO:0031324;negative regulation of cellular metabolic process;3.33720185799051e-10!GO:0015630;microtubule cytoskeleton;3.79942712959032e-10!GO:0006399;tRNA metabolic process;4.09154962810902e-10!GO:0051186;cofactor metabolic process;4.25485244466743e-10!GO:0006364;rRNA processing;4.25992135405373e-10!GO:0005643;nuclear pore;5.00984824460851e-10!GO:0065004;protein-DNA complex assembly;5.03237718796095e-10!GO:0006793;phosphorus metabolic process;6.4488596677695e-10!GO:0006796;phosphate metabolic process;6.4488596677695e-10!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;9.89822898482823e-10!GO:0016881;acid-amino acid ligase activity;1.1329940317962e-09!GO:0016072;rRNA metabolic process;1.15804572307716e-09!GO:0005793;ER-Golgi intermediate compartment;1.63629057289841e-09!GO:0005783;endoplasmic reticulum;2.11224630388611e-09!GO:0009892;negative regulation of metabolic process;2.33060203340822e-09!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;2.47166894411436e-09!GO:0043566;structure-specific DNA binding;2.61102928620384e-09!GO:0065002;intracellular protein transport across a membrane;3.6744299102544e-09!GO:0000279;M phase;4.05043325865656e-09!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;4.41544693593907e-09!GO:0004812;aminoacyl-tRNA ligase activity;4.41544693593907e-09!GO:0016875;ligase activity, forming carbon-oxygen bonds;4.41544693593907e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;4.88635321407119e-09!GO:0019222;regulation of metabolic process;5.40273776196535e-09!GO:0051028;mRNA transport;8.47604622666927e-09!GO:0016481;negative regulation of transcription;9.26426278082469e-09!GO:0043038;amino acid activation;1.01062786694755e-08!GO:0006418;tRNA aminoacylation for protein translation;1.01062786694755e-08!GO:0043039;tRNA aminoacylation;1.01062786694755e-08!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.50360349654733e-08!GO:0016564;transcription repressor activity;1.79353154637439e-08!GO:0009259;ribonucleotide metabolic process;1.97908465079617e-08!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.99207002774053e-08!GO:0031497;chromatin assembly;2.18639701426008e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;2.25181983913836e-08!GO:0003682;chromatin binding;2.90628271899608e-08!GO:0045941;positive regulation of transcription;2.94485112042043e-08!GO:0006163;purine nucleotide metabolic process;3.05117534382771e-08!GO:0051246;regulation of protein metabolic process;3.23644826553576e-08!GO:0044432;endoplasmic reticulum part;3.44075624321489e-08!GO:0006334;nucleosome assembly;3.51021092576193e-08!GO:0006164;purine nucleotide biosynthetic process;3.73626029367505e-08!GO:0046930;pore complex;3.77418183484485e-08!GO:0003714;transcription corepressor activity;4.21697805950331e-08!GO:0016310;phosphorylation;5.0868003248654e-08!GO:0016740;transferase activity;6.58696436288432e-08!GO:0009260;ribonucleotide biosynthetic process;8.13307637557332e-08!GO:0000245;spliceosome assembly;8.69439644418371e-08!GO:0006461;protein complex assembly;1.06438284205379e-07!GO:0016772;transferase activity, transferring phosphorus-containing groups;1.24488230126072e-07!GO:0006732;coenzyme metabolic process;1.31705814807727e-07!GO:0008565;protein transporter activity;1.41008959228099e-07!GO:0009055;electron carrier activity;1.43772328165634e-07!GO:0009150;purine ribonucleotide metabolic process;1.71627864450322e-07!GO:0015986;ATP synthesis coupled proton transport;1.72690758920738e-07!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.72690758920738e-07!GO:0006606;protein import into nucleus;2.05543411385058e-07!GO:0005813;centrosome;2.05543411385058e-07!GO:0051170;nuclear import;2.0773843967866e-07!GO:0009152;purine ribonucleotide biosynthetic process;2.10473157653216e-07!GO:0032446;protein modification by small protein conjugation;2.21311711276821e-07!GO:0048522;positive regulation of cellular process;2.21649201234472e-07!GO:0045893;positive regulation of transcription, DNA-dependent;2.3530756078344e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;3.03148919780335e-07!GO:0016567;protein ubiquitination;3.05979554559626e-07!GO:0005815;microtubule organizing center;3.63026087495377e-07!GO:0030532;small nuclear ribonucleoprotein complex;3.82175769945389e-07!GO:0019829;cation-transporting ATPase activity;3.92015315965175e-07!GO:0003697;single-stranded DNA binding;4.23548222458827e-07!GO:0003713;transcription coactivator activity;4.64023032454491e-07!GO:0006261;DNA-dependent DNA replication;4.73704987650645e-07!GO:0003724;RNA helicase activity;4.88565639015205e-07!GO:0009141;nucleoside triphosphate metabolic process;4.99748963550763e-07!GO:0009199;ribonucleoside triphosphate metabolic process;5.99454376945858e-07!GO:0005768;endosome;6.42094342946521e-07!GO:0065007;biological regulation;7.66933972271803e-07!GO:0006888;ER to Golgi vesicle-mediated transport;7.79739024705568e-07!GO:0046034;ATP metabolic process;1.05977058371475e-06!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.25368746621287e-06!GO:0009144;purine nucleoside triphosphate metabolic process;1.25368746621287e-06!GO:0015078;hydrogen ion transmembrane transporter activity;1.35961877452347e-06!GO:0009056;catabolic process;1.39049547654242e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.39574960690523e-06!GO:0043067;regulation of programmed cell death;1.44015307395269e-06!GO:0009142;nucleoside triphosphate biosynthetic process;1.47959723839807e-06!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.47959723839807e-06!GO:0042981;regulation of apoptosis;1.51560674263168e-06!GO:0003702;RNA polymerase II transcription factor activity;1.92952254948592e-06!GO:0006754;ATP biosynthetic process;1.96560440326703e-06!GO:0006753;nucleoside phosphate metabolic process;1.96560440326703e-06!GO:0000151;ubiquitin ligase complex;1.96602180894262e-06!GO:0016469;proton-transporting two-sector ATPase complex;2.17777778509697e-06!GO:0031323;regulation of cellular metabolic process;2.38699735563282e-06!GO:0051427;hormone receptor binding;2.38699735563282e-06!GO:0044431;Golgi apparatus part;2.78586356463116e-06!GO:0005819;spindle;2.78586356463116e-06!GO:0016779;nucleotidyltransferase activity;3.00521639092516e-06!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;3.10251326603523e-06!GO:0009145;purine nucleoside triphosphate biosynthetic process;3.10251326603523e-06!GO:0031252;leading edge;3.13884471940541e-06!GO:0051188;cofactor biosynthetic process;3.53314197468657e-06!GO:0045786;negative regulation of progression through cell cycle;3.6170204353879e-06!GO:0007051;spindle organization and biogenesis;4.37419141978342e-06!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;5.044134907898e-06!GO:0045892;negative regulation of transcription, DNA-dependent;5.06499698377716e-06!GO:0007005;mitochondrion organization and biogenesis;5.25400930181551e-06!GO:0042175;nuclear envelope-endoplasmic reticulum network;5.35330664004423e-06!GO:0045259;proton-transporting ATP synthase complex;5.4843263024737e-06!GO:0035257;nuclear hormone receptor binding;5.53350053630492e-06!GO:0000775;chromosome, pericentric region;6.1663995858304e-06!GO:0006350;transcription;7.56506609537594e-06!GO:0003690;double-stranded DNA binding;7.65820750787496e-06!GO:0043069;negative regulation of programmed cell death;8.69995682721801e-06!GO:0043623;cellular protein complex assembly;9.65778152278348e-06!GO:0003899;DNA-directed RNA polymerase activity;1.08299517302998e-05!GO:0009060;aerobic respiration;1.3450232334354e-05!GO:0007010;cytoskeleton organization and biogenesis;1.53099989219543e-05!GO:0005789;endoplasmic reticulum membrane;1.72572819545048e-05!GO:0043066;negative regulation of apoptosis;1.87333125655429e-05!GO:0019899;enzyme binding;2.92855320621048e-05!GO:0006916;anti-apoptosis;3.22368109484592e-05!GO:0006613;cotranslational protein targeting to membrane;3.43846973356539e-05!GO:0051329;interphase of mitotic cell cycle;3.45828186712575e-05!GO:0005762;mitochondrial large ribosomal subunit;3.85528009943797e-05!GO:0000315;organellar large ribosomal subunit;3.85528009943797e-05!GO:0005769;early endosome;4.31447941210053e-05!GO:0004674;protein serine/threonine kinase activity;4.4273840600159e-05!GO:0031072;heat shock protein binding;5.01619842991193e-05!GO:0009893;positive regulation of metabolic process;5.14952924362031e-05!GO:0009117;nucleotide metabolic process;5.72901311455816e-05!GO:0008186;RNA-dependent ATPase activity;5.90380891311135e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;6.01729609741768e-05!GO:0044440;endosomal part;6.02427324203826e-05!GO:0010008;endosome membrane;6.02427324203826e-05!GO:0008361;regulation of cell size;6.42851627011511e-05!GO:0006752;group transfer coenzyme metabolic process;6.60727935891146e-05!GO:0010468;regulation of gene expression;7.17032004888241e-05!GO:0045333;cellular respiration;7.17169120058001e-05!GO:0000139;Golgi membrane;7.68702159514987e-05!GO:0006099;tricarboxylic acid cycle;7.89705351053661e-05!GO:0046356;acetyl-CoA catabolic process;7.89705351053661e-05!GO:0000314;organellar small ribosomal subunit;7.93315483274968e-05!GO:0005763;mitochondrial small ribosomal subunit;7.93315483274968e-05!GO:0048475;coated membrane;8.2801298500683e-05!GO:0030117;membrane coat;8.2801298500683e-05!GO:0016049;cell growth;8.32455034392378e-05!GO:0009108;coenzyme biosynthetic process;8.38061849021223e-05!GO:0030120;vesicle coat;9.21429205496641e-05!GO:0030662;coated vesicle membrane;9.21429205496641e-05!GO:0000786;nucleosome;9.21429205496641e-05!GO:0016044;membrane organization and biogenesis;9.42432967450662e-05!GO:0048518;positive regulation of biological process;9.88380307742398e-05!GO:0005657;replication fork;0.000105448637409327!GO:0007243;protein kinase cascade;0.000115726257123172!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.00012484458136026!GO:0043021;ribonucleoprotein binding;0.000126943809705984!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.000131562129041645!GO:0016363;nuclear matrix;0.000133721457554316!GO:0003924;GTPase activity;0.000134194131467075!GO:0005788;endoplasmic reticulum lumen;0.000134364051264199!GO:0051325;interphase;0.000137219867073944!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00014381691331923!GO:0051187;cofactor catabolic process;0.000157774981364407!GO:0044452;nucleolar part;0.000164381938143848!GO:0005839;proteasome core complex (sensu Eukaryota);0.000172456353013498!GO:0006402;mRNA catabolic process;0.000172789141339792!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.000172789141339792!GO:0004004;ATP-dependent RNA helicase activity;0.000174305769906841!GO:0009109;coenzyme catabolic process;0.000174435160817958!GO:0005770;late endosome;0.000181258273128064!GO:0030036;actin cytoskeleton organization and biogenesis;0.000189876817113182!GO:0006084;acetyl-CoA metabolic process;0.000206779453091057!GO:0006383;transcription from RNA polymerase III promoter;0.000208435826434789!GO:0016787;hydrolase activity;0.000208721875624115!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.000208885534680477!GO:0031325;positive regulation of cellular metabolic process;0.000223170433552517!GO:0016859;cis-trans isomerase activity;0.000236418924063832!GO:0000075;cell cycle checkpoint;0.000272371274681708!GO:0003729;mRNA binding;0.00027705158113681!GO:0051168;nuclear export;0.000331382326882588!GO:0032508;DNA duplex unwinding;0.00035354453046893!GO:0032392;DNA geometric change;0.00035354453046893!GO:0000776;kinetochore;0.0003789238792847!GO:0008092;cytoskeletal protein binding;0.000379263668751112!GO:0048468;cell development;0.000385933970583889!GO:0045454;cell redox homeostasis;0.000400528127545364!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.000426055164914953!GO:0032774;RNA biosynthetic process;0.000427235954953112!GO:0001558;regulation of cell growth;0.000429564680179191!GO:0043681;protein import into mitochondrion;0.000464703723584126!GO:0008047;enzyme activator activity;0.000497486271166676!GO:0006351;transcription, DNA-dependent;0.000518794592184984!GO:0005874;microtubule;0.000537115811735495!GO:0030867;rough endoplasmic reticulum membrane;0.000565642112331272!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000566455131562357!GO:0005525;GTP binding;0.000599271468433813!GO:0003678;DNA helicase activity;0.000647200879643434!GO:0006268;DNA unwinding during replication;0.000668881388781905!GO:0006414;translational elongation;0.000710719200875729!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000723287886924966!GO:0033116;ER-Golgi intermediate compartment membrane;0.00079985153880359!GO:0008094;DNA-dependent ATPase activity;0.00079985153880359!GO:0004298;threonine endopeptidase activity;0.000802859471325247!GO:0001726;ruffle;0.000803410222463366!GO:0000049;tRNA binding;0.000819563458154584!GO:0007052;mitotic spindle organization and biogenesis;0.000831866920831259!GO:0006338;chromatin remodeling;0.000843796660814541!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000857295781155849!GO:0046983;protein dimerization activity;0.000903129823459653!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000950181612237562!GO:0008250;oligosaccharyl transferase complex;0.000954520581544968!GO:0042802;identical protein binding;0.000959652483908993!GO:0005048;signal sequence binding;0.00107981929552903!GO:0035258;steroid hormone receptor binding;0.00109546574849375!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00112301133533583!GO:0005798;Golgi-associated vesicle;0.00114653545740365!GO:0051052;regulation of DNA metabolic process;0.00114992384019703!GO:0005852;eukaryotic translation initiation factor 3 complex;0.0011615175590182!GO:0006626;protein targeting to mitochondrion;0.00119563094209313!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00126387201732361!GO:0004576;oligosaccharyl transferase activity;0.00126646608310645!GO:0030029;actin filament-based process;0.00130408966765268!GO:0045944;positive regulation of transcription from RNA polymerase II promoter;0.00135831107367001!GO:0016023;cytoplasmic membrane-bound vesicle;0.00136496944905274!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00137605460346262!GO:0006401;RNA catabolic process;0.00139047599716872!GO:0048471;perinuclear region of cytoplasm;0.0014139062660583!GO:0005096;GTPase activator activity;0.00147978930713342!GO:0006612;protein targeting to membrane;0.00150360085512256!GO:0031988;membrane-bound vesicle;0.00154959085862705!GO:0008654;phospholipid biosynthetic process;0.00156832144805504!GO:0016853;isomerase activity;0.00162929574501192!GO:0016272;prefoldin complex;0.00167172477951215!GO:0016301;kinase activity;0.00174693067538042!GO:0007017;microtubule-based process;0.00176198171109718!GO:0000287;magnesium ion binding;0.00185439931288144!GO:0048500;signal recognition particle;0.00198207775321151!GO:0006302;double-strand break repair;0.00199007256761713!GO:0051101;regulation of DNA binding;0.00202954506495613!GO:0005885;Arp2/3 protein complex;0.00216605725535586!GO:0045449;regulation of transcription;0.00223704138643335!GO:0032561;guanyl ribonucleotide binding;0.0022861138876217!GO:0019001;guanyl nucleotide binding;0.0022861138876217!GO:0030880;RNA polymerase complex;0.00233112012862504!GO:0016741;transferase activity, transferring one-carbon groups;0.00238903161028655!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.00240026442828036!GO:0003746;translation elongation factor activity;0.00261678682014424!GO:0006839;mitochondrial transport;0.00269096297389481!GO:0040008;regulation of growth;0.00269266959228721!GO:0018196;peptidyl-asparagine modification;0.0026933963827251!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0026933963827251!GO:0004527;exonuclease activity;0.00281774756289762!GO:0006352;transcription initiation;0.00283446753650573!GO:0007006;mitochondrial membrane organization and biogenesis;0.00289795631586656!GO:0008168;methyltransferase activity;0.00307690914083955!GO:0008139;nuclear localization sequence binding;0.00311224329668089!GO:0006611;protein export from nucleus;0.00364275842626153!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.00369501602159286!GO:0008312;7S RNA binding;0.003708294651323!GO:0007264;small GTPase mediated signal transduction;0.00372240543343428!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00375367413785257!GO:0000059;protein import into nucleus, docking;0.0037738600970177!GO:0051789;response to protein stimulus;0.0037738600970177!GO:0006986;response to unfolded protein;0.0037738600970177!GO:0003677;DNA binding;0.00378444202779617!GO:0006984;ER-nuclear signaling pathway;0.00386034435809203!GO:0045045;secretory pathway;0.00387816562177105!GO:0051252;regulation of RNA metabolic process;0.00404043746953035!GO:0040029;regulation of gene expression, epigenetic;0.00415997255606438!GO:0009165;nucleotide biosynthetic process;0.00417659138539558!GO:0051920;peroxiredoxin activity;0.00418400339023018!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.00422983076334277!GO:0015399;primary active transmembrane transporter activity;0.00422983076334277!GO:0008033;tRNA processing;0.00423357353148918!GO:0016584;nucleosome positioning;0.00424432864660542!GO:0019843;rRNA binding;0.00427292686200639!GO:0065009;regulation of a molecular function;0.00428656070414299!GO:0015980;energy derivation by oxidation of organic compounds;0.00447665621474957!GO:0030132;clathrin coat of coated pit;0.00450366660637876!GO:0005905;coated pit;0.00450413887849918!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00451023010109521!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00451023010109521!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00451023010109521!GO:0006892;post-Golgi vesicle-mediated transport;0.00461475265388867!GO:0000792;heterochromatin;0.00484301247616307!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00484644431789358!GO:0003684;damaged DNA binding;0.00485616992414228!GO:0051087;chaperone binding;0.00487641316548292!GO:0007059;chromosome segregation;0.00490374809973429!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00491009388169733!GO:0045047;protein targeting to ER;0.00491009388169733!GO:0016311;dephosphorylation;0.00508437381888308!GO:0022415;viral reproductive process;0.00512501429884409!GO:0031968;organelle outer membrane;0.00514516575493865!GO:0031982;vesicle;0.00520099483243474!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00525496712437921!GO:0000428;DNA-directed RNA polymerase complex;0.00525496712437921!GO:0003711;transcription elongation regulator activity;0.00526185359460178!GO:0019783;small conjugating protein-specific protease activity;0.0054944190858343!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00554087570898234!GO:0006376;mRNA splice site selection;0.00554250686244253!GO:0000389;nuclear mRNA 3'-splice site recognition;0.00554250686244253!GO:0022411;cellular component disassembly;0.00563694235242674!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0056940716956605!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0056940716956605!GO:0019867;outer membrane;0.0056940716956605!GO:0000082;G1/S transition of mitotic cell cycle;0.00589115083615074!GO:0004843;ubiquitin-specific protease activity;0.00591707351829254!GO:0031410;cytoplasmic vesicle;0.00602925970834826!GO:0006897;endocytosis;0.00691189137078064!GO:0010324;membrane invagination;0.00691189137078064!GO:0046822;regulation of nucleocytoplasmic transport;0.00714740959037764!GO:0051098;regulation of binding;0.00751684038603485!GO:0007093;mitotic cell cycle checkpoint;0.00770103491724527!GO:0000902;cell morphogenesis;0.00775601626454217!GO:0032989;cellular structure morphogenesis;0.00775601626454217!GO:0030695;GTPase regulator activity;0.00830871461883593!GO:0005862;muscle thin filament tropomyosin;0.00838587887738475!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00850190081758164!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00854618526213945!GO:0006144;purine base metabolic process;0.00871262622616415!GO:0032984;macromolecular complex disassembly;0.00882723431424638!GO:0000922;spindle pole;0.00886106264297269!GO:0009303;rRNA transcription;0.00948474547113785!GO:0005684;U2-dependent spliceosome;0.00948474547113785!GO:0030176;integral to endoplasmic reticulum membrane;0.00972537602224671!GO:0030027;lamellipodium;0.00980696580637656!GO:0006417;regulation of translation;0.0099622382252803!GO:0043488;regulation of mRNA stability;0.0100543726214697!GO:0043487;regulation of RNA stability;0.0100543726214697!GO:0005669;transcription factor TFIID complex;0.0100989995408002!GO:0030521;androgen receptor signaling pathway;0.0101206295917317!GO:0006310;DNA recombination;0.0101206295917317!GO:0046966;thyroid hormone receptor binding;0.010165317420039!GO:0048487;beta-tubulin binding;0.0101777440924013!GO:0017166;vinculin binding;0.0104433645867662!GO:0009116;nucleoside metabolic process;0.0104633043957634!GO:0005741;mitochondrial outer membrane;0.0105184365399155!GO:0030134;ER to Golgi transport vesicle;0.0105208389793212!GO:0016281;eukaryotic translation initiation factor 4F complex;0.010521748398716!GO:0007265;Ras protein signal transduction;0.0105686087084481!GO:0016251;general RNA polymerase II transcription factor activity;0.0106596148113272!GO:0043624;cellular protein complex disassembly;0.0112147078271647!GO:0030118;clathrin coat;0.0114047227868328!GO:0005637;nuclear inner membrane;0.0115044958677205!GO:0031625;ubiquitin protein ligase binding;0.0115044958677205!GO:0006355;regulation of transcription, DNA-dependent;0.0116474165675861!GO:0031901;early endosome membrane;0.0119063637175754!GO:0004221;ubiquitin thiolesterase activity;0.0120594724271654!GO:0015631;tubulin binding;0.0121445251151875!GO:0043492;ATPase activity, coupled to movement of substances;0.0121473214792979!GO:0006284;base-excision repair;0.0123270033834396!GO:0006891;intra-Golgi vesicle-mediated transport;0.0123651487020464!GO:0008022;protein C-terminus binding;0.0123975598067551!GO:0008287;protein serine/threonine phosphatase complex;0.012592264740067!GO:0016791;phosphoric monoester hydrolase activity;0.0131100833071581!GO:0008243;plasminogen activator activity;0.013230369229867!GO:0015992;proton transport;0.0132873175634532!GO:0005938;cell cortex;0.0135998694867211!GO:0016197;endosome transport;0.0137500251193522!GO:0007030;Golgi organization and biogenesis;0.014046603879986!GO:0007242;intracellular signaling cascade;0.0140682273175913!GO:0030145;manganese ion binding;0.0140947192028121!GO:0032200;telomere organization and biogenesis;0.0143030866216251!GO:0000723;telomere maintenance;0.0143030866216251!GO:0043241;protein complex disassembly;0.0144432745539702!GO:0031124;mRNA 3'-end processing;0.0145031885923748!GO:0004721;phosphoprotein phosphatase activity;0.0145031885923748!GO:0008180;signalosome;0.014650626830913!GO:0030865;cortical cytoskeleton organization and biogenesis;0.0149794466554349!GO:0007569;cell aging;0.0150940388939634!GO:0005083;small GTPase regulator activity;0.015159347851146!GO:0006818;hydrogen transport;0.0153410573312743!GO:0050681;androgen receptor binding;0.0153410573312743!GO:0043022;ribosome binding;0.0153941052949017!GO:0043284;biopolymer biosynthetic process;0.0154935128592161!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0157711192300001!GO:0015002;heme-copper terminal oxidase activity;0.0157711192300001!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0157711192300001!GO:0004129;cytochrome-c oxidase activity;0.0157711192300001!GO:0005876;spindle microtubule;0.0160653688906399!GO:0008632;apoptotic program;0.0162039021634176!GO:0016790;thiolester hydrolase activity;0.0164691057951272!GO:0003725;double-stranded RNA binding;0.016838099014977!GO:0030127;COPII vesicle coat;0.016838099014977!GO:0012507;ER to Golgi transport vesicle membrane;0.016838099014977!GO:0000118;histone deacetylase complex;0.0169601338883129!GO:0006541;glutamine metabolic process;0.0169935289273383!GO:0008629;induction of apoptosis by intracellular signals;0.0170492046380744!GO:0006270;DNA replication initiation;0.0174961304702473!GO:0043189;H4/H2A histone acetyltransferase complex;0.0174961304702473!GO:0009112;nucleobase metabolic process;0.0175497250197944!GO:0007088;regulation of mitosis;0.0177216655284416!GO:0043596;nuclear replication fork;0.0177389442052637!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.0182506779894751!GO:0000178;exosome (RNase complex);0.0185390880718664!GO:0005856;cytoskeleton;0.0191286331628998!GO:0008276;protein methyltransferase activity;0.0193995084174344!GO:0016585;chromatin remodeling complex;0.0193995084174344!GO:0031529;ruffle organization and biogenesis;0.0197300514862547!GO:0030518;steroid hormone receptor signaling pathway;0.0197340265087425!GO:0006405;RNA export from nucleus;0.0200692886178921!GO:0000910;cytokinesis;0.0200759497256561!GO:0004003;ATP-dependent DNA helicase activity;0.0202159574384471!GO:0009966;regulation of signal transduction;0.0206732107206351!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.0209637549165475!GO:0005791;rough endoplasmic reticulum;0.0215471253351459!GO:0030433;ER-associated protein catabolic process;0.0219376811865693!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0219376811865693!GO:0008286;insulin receptor signaling pathway;0.0220227523932491!GO:0006275;regulation of DNA replication;0.02232187221683!GO:0009889;regulation of biosynthetic process;0.0227255019535535!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.022925897062415!GO:0008283;cell proliferation;0.0230806039902353!GO:0005100;Rho GTPase activator activity;0.0239422302896631!GO:0005832;chaperonin-containing T-complex;0.0241125479825435!GO:0046483;heterocycle metabolic process;0.024454471545453!GO:0030496;midbody;0.0250497734860815!GO:0042770;DNA damage response, signal transduction;0.025485332609707!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0259241888602083!GO:0031326;regulation of cellular biosynthetic process;0.0262229050159778!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.0263968096469424!GO:0016579;protein deubiquitination;0.027283148098928!GO:0006354;RNA elongation;0.0274460200974478!GO:0030658;transport vesicle membrane;0.0276463857173652!GO:0006595;polyamine metabolic process;0.0279224726883318!GO:0005875;microtubule associated complex;0.0287277362613624!GO:0007050;cell cycle arrest;0.0287277362613624!GO:0022890;inorganic cation transmembrane transporter activity;0.0291572069103415!GO:0007346;regulation of progression through mitotic cell cycle;0.0304506172318504!GO:0006607;NLS-bearing substrate import into nucleus;0.0313728897813775!GO:0019079;viral genome replication;0.0314302814538217!GO:0005869;dynactin complex;0.0315479843998448!GO:0035267;NuA4 histone acetyltransferase complex;0.0317176352468226!GO:0042393;histone binding;0.0317176352468226!GO:0006520;amino acid metabolic process;0.0317945896009068!GO:0032940;secretion by cell;0.0317945896009068!GO:0046474;glycerophospholipid biosynthetic process;0.0319364115096003!GO:0000096;sulfur amino acid metabolic process;0.0325795872275131!GO:0008154;actin polymerization and/or depolymerization;0.0327890685779928!GO:0004672;protein kinase activity;0.0342682951027628!GO:0032507;maintenance of cellular protein localization;0.0351659835654433!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0363715221025311!GO:0010257;NADH dehydrogenase complex assembly;0.0363715221025311!GO:0033108;mitochondrial respiratory chain complex assembly;0.0363715221025311!GO:0004518;nuclease activity;0.0365259321099144!GO:0033673;negative regulation of kinase activity;0.0365259321099144!GO:0006469;negative regulation of protein kinase activity;0.0365259321099144!GO:0006091;generation of precursor metabolites and energy;0.0372186658203904!GO:0008234;cysteine-type peptidase activity;0.0372924226501384!GO:0019206;nucleoside kinase activity;0.0378233720075596!GO:0008408;3'-5' exonuclease activity;0.0378233720075596!GO:0000123;histone acetyltransferase complex;0.0379353252048523!GO:0030866;cortical actin cytoskeleton organization and biogenesis;0.038453721455093!GO:0019904;protein domain specific binding;0.0391431675232471!GO:0047485;protein N-terminus binding;0.0399196696463666!GO:0006470;protein amino acid dephosphorylation;0.040540721794655!GO:0006289;nucleotide-excision repair;0.0410399069164743!GO:0043407;negative regulation of MAP kinase activity;0.0417805390481845!GO:0043130;ubiquitin binding;0.0417805390481845!GO:0032182;small conjugating protein binding;0.0417805390481845!GO:0004532;exoribonuclease activity;0.0426732329387411!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0426732329387411!GO:0008097;5S rRNA binding;0.0427429054331564!GO:0043065;positive regulation of apoptosis;0.0437839722577992!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0439210238580351!GO:0030119;AP-type membrane coat adaptor complex;0.0439330589271036!GO:0030911;TPR domain binding;0.0446067679198936!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0448678232879979!GO:0004680;casein kinase activity;0.0452836825233036!GO:0032259;methylation;0.0452836825233036!GO:0030031;cell projection biogenesis;0.0454697205839429!GO:0030384;phosphoinositide metabolic process;0.0470125673146437!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0470321420925036!GO:0042026;protein refolding;0.0472815371992444!GO:0031123;RNA 3'-end processing;0.0473834103327413!GO:0006509;membrane protein ectodomain proteolysis;0.0473834103327413!GO:0033619;membrane protein proteolysis;0.0473834103327413!GO:0051348;negative regulation of transferase activity;0.0473914180010764!GO:0007004;telomere maintenance via telomerase;0.0476566893460214!GO:0006650;glycerophospholipid metabolic process;0.0480713808000764!GO:0000228;nuclear chromosome;0.0480713808000764!GO:0000725;recombinational repair;0.0481098359345582!GO:0000724;double-strand break repair via homologous recombination;0.0481098359345582!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0481098359345582!GO:0003779;actin binding;0.0485157587966712!GO:0030032;lamellipodium biogenesis;0.0486447954272169!GO:0006378;mRNA polyadenylation;0.0488477270970012!GO:0004239;methionyl aminopeptidase activity;0.0494331552055395!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0495023639517175 | |||
|sample_id=10510 | |sample_id=10510 | ||
|sample_note= | |sample_note= | ||
| Line 76: | Line 99: | ||
|sample_tissue=bone | |sample_tissue=bone | ||
|top_motifs=TFDP1:2.61243444084;PAX8:1.54651124803;FOX{I1,J2}:1.52565362021;EGR1..3:1.40452521392;PDX1:1.32048780396;ONECUT1,2:1.24952583833;TFAP2B:1.21850752979;HBP1_HMGB_SSRP1_UBTF:1.20561602007;EN1,2:1.17279746428;ZFP161:1.14994286983;BREu{core}:1.12270707369;HIC1:1.06466641215;SOX17:1.05108430034;T:1.00065352165;POU6F1:0.998041696548;MTF1:0.980762320965;FOXQ1:0.95080066228;HOXA9_MEIS1:0.900705644236;MTE{core}:0.855021806085;TFAP2{A,C}:0.848819327056;MZF1:0.844545640893;POU5F1:0.805540724275;PRRX1,2:0.787110961838;E2F1..5:0.766902102347;FOX{F1,F2,J1}:0.759327698337;HES1:0.737602526235;XBP1:0.733874420031;GFI1:0.716618124505;LEF1_TCF7_TCF7L1,2:0.681557069593;CDC5L:0.664291967992;MED-1{core}:0.587572281545;FOXA2:0.565525218062;NANOG:0.514569331947;LHX3,4:0.474730215559;PAX6:0.470565551308;FOS_FOS{B,L1}_JUN{B,D}:0.42830734469;ADNP_IRX_SIX_ZHX:0.390122305609;NHLH1,2:0.389810688144;bHLH_family:0.381815642606;POU2F1..3:0.379614506121;BACH2:0.362660135356;GZF1:0.337819324727;AR:0.336408257813;DBP:0.325378376667;GCM1,2:0.310940897121;PAX3,7:0.308455449746;GATA6:0.305534541813;PRDM1:0.296682630215;FOSL2:0.295806274139;HLF:0.285224497973;CRX:0.281569644985;MYB:0.276217951879;PBX1:0.274898214583;TEF:0.270152252562;PATZ1:0.269073707077;GTF2I:0.258710953739;NFIX:0.255237272462;POU1F1:0.244965081719;HOX{A5,B5}:0.235237077363;TFAP4:0.227552544266;CEBPA,B_DDIT3:0.22694370622;HOX{A6,A7,B6,B7}:0.223392687875;ZBTB6:0.202853035656;NR3C1:0.181586281679;NFIL3:0.158119560336;NFE2:0.149391103719;CUX2:0.147421498035;SOX5:0.137423713326;FOX{D1,D2}:0.124706674488;NFY{A,B,C}:0.110476005344;BPTF:0.102929932671;MYOD1:0.101165905194;TLX1..3_NFIC{dimer}:0.0815988331161;NKX6-1,2:0.0792579771948;MYBL2:0.0741448753154;GTF2A1,2:0.0738573539937;VSX1,2:0.0682654754574;XCPE1{core}:0.0644981254361;ZNF143:0.0619869779747;HSF1,2:0.0559528769627;TP53:0.0556479861193;SOX2:0.0498152965566;STAT2,4,6:0.0474708931313;FOXD3:0.039236314605;TBP:0.0278528936175;REST:0.0277716120498;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.025740631831;ZNF148:0.0222943951982;NRF1:0.0222067615367;ATF2:0.0158960116444;GFI1B:0.00917153954737;AHR_ARNT_ARNT2:0.00914633019491;RFX1:-0.0149183802415;SOX{8,9,10}:-0.015063663507;TAL1_TCF{3,4,12}:-0.0185875133885;ELK1,4_GABP{A,B1}:-0.0367671261029;MAZ:-0.0376607973414;ATF5_CREB3:-0.0475225142221;CREB1:-0.0589727295716;MEF2{A,B,C,D}:-0.0756374163199;DMAP1_NCOR{1,2}_SMARC:-0.0797706665336;TBX4,5:-0.0801614321783;ZBTB16:-0.0832490106057;ZNF384:-0.0834432060102;PITX1..3:-0.0881801837177;HNF1A:-0.0910892875756;NFE2L2:-0.0974606635827;NFKB1_REL_RELA:-0.101444022084;RUNX1..3:-0.102288476168;NR5A1,2:-0.107196201278;TEAD1:-0.110234311756;OCT4_SOX2{dimer}:-0.115377762531;PAX5:-0.130306090652;MAFB:-0.151447745922;FOXP1:-0.153623070179;NKX2-1,4:-0.155361300163;ELF1,2,4:-0.157989817789;NKX3-1:-0.160788970599;SP1:-0.201020097013;NR6A1:-0.207336478185;HOX{A4,D4}:-0.210268979897;PAX2:-0.211752079047;SPI1:-0.213297964525;TGIF1:-0.233214466881;ATF4:-0.238530676563;IKZF2:-0.258119146916;ETS1,2:-0.263553798151;PPARG:-0.292558521222;POU3F1..4:-0.300796539669;STAT5{A,B}:-0.311209154748;MYFfamily:-0.313317399013;FOXN1:-0.317418274258;PAX1,9:-0.32385917442;RORA:-0.326425067632;SPIB:-0.328443560018;ATF6:-0.347435118776;ZEB1:-0.351352667701;YY1:-0.357081552721;SMAD1..7,9:-0.363027837675;CDX1,2,4:-0.367806851286;FOXM1:-0.372506415684;SNAI1..3:-0.376714041956;TFCP2:-0.377348600155;IKZF1:-0.380926084916;NKX2-3_NKX2-5:-0.396381753238;KLF4:-0.396759285213;NFE2L1:-0.401720927732;PAX4:-0.41959672471;GATA4:-0.42684497538;HNF4A_NR2F1,2:-0.434501556251;JUN:-0.452607402587;SRF:-0.4550204412;ALX4:-0.477711846671;ZIC1..3:-0.525898831113;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.531219581477;ZNF423:-0.542453536715;RBPJ:-0.544520404657;RREB1:-0.545821637653;NR1H4:-0.556791125502;IRF7:-0.571639251464;ARID5B:-0.58815512017;ALX1:-0.59003150724;FOXL1:-0.595219970222;HMGA1,2:-0.61575537292;NANOG{mouse}:-0.634346145896;ZNF238:-0.640102312298;RFX2..5_RFXANK_RFXAP:-0.643677330407;TOPORS:-0.679518203066;NFATC1..3:-0.680252141192;LMO2:-0.700500462975;EBF1:-0.731406133085;RXR{A,B,G}:-0.741753022296;IRF1,2:-0.74462080034;FOXO1,3,4:-0.753781337725;HIF1A:-0.778227177234;SPZ1:-0.779276205957;EVI1:-0.85114099226;UFEwm:-0.884990126522;GLI1..3:-0.913564090045;TLX2:-0.935766710996;HAND1,2:-1.01101458228;FOXP3:-1.04936858173;NKX3-2:-1.06023147723;AIRE:-1.09447219675;HMX1:-1.10218394332;SREBF1,2:-1.13192848269;NKX2-2,8:-1.18188046285;RXRA_VDR{dimer}:-1.2791086312;ESR1:-1.3356384546;ESRRA:-1.34256959084;EP300:-1.38206006877;STAT1,3:-1.72873299632 | |top_motifs=TFDP1:2.61243444084;PAX8:1.54651124803;FOX{I1,J2}:1.52565362021;EGR1..3:1.40452521392;PDX1:1.32048780396;ONECUT1,2:1.24952583833;TFAP2B:1.21850752979;HBP1_HMGB_SSRP1_UBTF:1.20561602007;EN1,2:1.17279746428;ZFP161:1.14994286983;BREu{core}:1.12270707369;HIC1:1.06466641215;SOX17:1.05108430034;T:1.00065352165;POU6F1:0.998041696548;MTF1:0.980762320965;FOXQ1:0.95080066228;HOXA9_MEIS1:0.900705644236;MTE{core}:0.855021806085;TFAP2{A,C}:0.848819327056;MZF1:0.844545640893;POU5F1:0.805540724275;PRRX1,2:0.787110961838;E2F1..5:0.766902102347;FOX{F1,F2,J1}:0.759327698337;HES1:0.737602526235;XBP1:0.733874420031;GFI1:0.716618124505;LEF1_TCF7_TCF7L1,2:0.681557069593;CDC5L:0.664291967992;MED-1{core}:0.587572281545;FOXA2:0.565525218062;NANOG:0.514569331947;LHX3,4:0.474730215559;PAX6:0.470565551308;FOS_FOS{B,L1}_JUN{B,D}:0.42830734469;ADNP_IRX_SIX_ZHX:0.390122305609;NHLH1,2:0.389810688144;bHLH_family:0.381815642606;POU2F1..3:0.379614506121;BACH2:0.362660135356;GZF1:0.337819324727;AR:0.336408257813;DBP:0.325378376667;GCM1,2:0.310940897121;PAX3,7:0.308455449746;GATA6:0.305534541813;PRDM1:0.296682630215;FOSL2:0.295806274139;HLF:0.285224497973;CRX:0.281569644985;MYB:0.276217951879;PBX1:0.274898214583;TEF:0.270152252562;PATZ1:0.269073707077;GTF2I:0.258710953739;NFIX:0.255237272462;POU1F1:0.244965081719;HOX{A5,B5}:0.235237077363;TFAP4:0.227552544266;CEBPA,B_DDIT3:0.22694370622;HOX{A6,A7,B6,B7}:0.223392687875;ZBTB6:0.202853035656;NR3C1:0.181586281679;NFIL3:0.158119560336;NFE2:0.149391103719;CUX2:0.147421498035;SOX5:0.137423713326;FOX{D1,D2}:0.124706674488;NFY{A,B,C}:0.110476005344;BPTF:0.102929932671;MYOD1:0.101165905194;TLX1..3_NFIC{dimer}:0.0815988331161;NKX6-1,2:0.0792579771948;MYBL2:0.0741448753154;GTF2A1,2:0.0738573539937;VSX1,2:0.0682654754574;XCPE1{core}:0.0644981254361;ZNF143:0.0619869779747;HSF1,2:0.0559528769627;TP53:0.0556479861193;SOX2:0.0498152965566;STAT2,4,6:0.0474708931313;FOXD3:0.039236314605;TBP:0.0278528936175;REST:0.0277716120498;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.025740631831;ZNF148:0.0222943951982;NRF1:0.0222067615367;ATF2:0.0158960116444;GFI1B:0.00917153954737;AHR_ARNT_ARNT2:0.00914633019491;RFX1:-0.0149183802415;SOX{8,9,10}:-0.015063663507;TAL1_TCF{3,4,12}:-0.0185875133885;ELK1,4_GABP{A,B1}:-0.0367671261029;MAZ:-0.0376607973414;ATF5_CREB3:-0.0475225142221;CREB1:-0.0589727295716;MEF2{A,B,C,D}:-0.0756374163199;DMAP1_NCOR{1,2}_SMARC:-0.0797706665336;TBX4,5:-0.0801614321783;ZBTB16:-0.0832490106057;ZNF384:-0.0834432060102;PITX1..3:-0.0881801837177;HNF1A:-0.0910892875756;NFE2L2:-0.0974606635827;NFKB1_REL_RELA:-0.101444022084;RUNX1..3:-0.102288476168;NR5A1,2:-0.107196201278;TEAD1:-0.110234311756;OCT4_SOX2{dimer}:-0.115377762531;PAX5:-0.130306090652;MAFB:-0.151447745922;FOXP1:-0.153623070179;NKX2-1,4:-0.155361300163;ELF1,2,4:-0.157989817789;NKX3-1:-0.160788970599;SP1:-0.201020097013;NR6A1:-0.207336478185;HOX{A4,D4}:-0.210268979897;PAX2:-0.211752079047;SPI1:-0.213297964525;TGIF1:-0.233214466881;ATF4:-0.238530676563;IKZF2:-0.258119146916;ETS1,2:-0.263553798151;PPARG:-0.292558521222;POU3F1..4:-0.300796539669;STAT5{A,B}:-0.311209154748;MYFfamily:-0.313317399013;FOXN1:-0.317418274258;PAX1,9:-0.32385917442;RORA:-0.326425067632;SPIB:-0.328443560018;ATF6:-0.347435118776;ZEB1:-0.351352667701;YY1:-0.357081552721;SMAD1..7,9:-0.363027837675;CDX1,2,4:-0.367806851286;FOXM1:-0.372506415684;SNAI1..3:-0.376714041956;TFCP2:-0.377348600155;IKZF1:-0.380926084916;NKX2-3_NKX2-5:-0.396381753238;KLF4:-0.396759285213;NFE2L1:-0.401720927732;PAX4:-0.41959672471;GATA4:-0.42684497538;HNF4A_NR2F1,2:-0.434501556251;JUN:-0.452607402587;SRF:-0.4550204412;ALX4:-0.477711846671;ZIC1..3:-0.525898831113;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.531219581477;ZNF423:-0.542453536715;RBPJ:-0.544520404657;RREB1:-0.545821637653;NR1H4:-0.556791125502;IRF7:-0.571639251464;ARID5B:-0.58815512017;ALX1:-0.59003150724;FOXL1:-0.595219970222;HMGA1,2:-0.61575537292;NANOG{mouse}:-0.634346145896;ZNF238:-0.640102312298;RFX2..5_RFXANK_RFXAP:-0.643677330407;TOPORS:-0.679518203066;NFATC1..3:-0.680252141192;LMO2:-0.700500462975;EBF1:-0.731406133085;RXR{A,B,G}:-0.741753022296;IRF1,2:-0.74462080034;FOXO1,3,4:-0.753781337725;HIF1A:-0.778227177234;SPZ1:-0.779276205957;EVI1:-0.85114099226;UFEwm:-0.884990126522;GLI1..3:-0.913564090045;TLX2:-0.935766710996;HAND1,2:-1.01101458228;FOXP3:-1.04936858173;NKX3-2:-1.06023147723;AIRE:-1.09447219675;HMX1:-1.10218394332;SREBF1,2:-1.13192848269;NKX2-2,8:-1.18188046285;RXRA_VDR{dimer}:-1.2791086312;ESR1:-1.3356384546;ESRRA:-1.34256959084;EP300:-1.38206006877;STAT1,3:-1.72873299632 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10510-107D6;search_select_hide=table117:FF:10510-107D6 | |||
}} | }} | ||
Latest revision as of 14:27, 3 June 2020
| Name: | osteosarcoma cell line:143B/TK^(-)neo^(R) |
|---|---|
| Species: | Human (Homo sapiens) |
| Library ID: | CNhs11279 |
| Sample type: | cell lines |
| Genomic View: | UCSC |
| RefEX: | Specific genes |
| CAGEd-oPOSSUM: | link |
| ZENBU report : | link |
| Additional information | ||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sample information
RNA information
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| CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| Download raw sequence, BAM & CTSS | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11279
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11279
| Novel motif | Logo | P-value |
|---|---|---|
| 1 | 1 | 0.00934 |
| 10 | 10 | 0.099 |
| 100 | 100 | 0.527 |
| 101 | 101 | 0.93 |
| 102 | 102 | 0.964 |
| 103 | 103 | 0.0778 |
| 104 | 104 | 0.896 |
| 105 | 105 | 0.897 |
| 106 | 106 | 0.365 |
| 107 | 107 | 0.542 |
| 108 | 108 | 0.536 |
| 109 | 109 | 0.106 |
| 11 | 11 | 0.0122 |
| 110 | 110 | 0.0918 |
| 111 | 111 | 0.398 |
| 112 | 112 | 0.00901 |
| 113 | 113 | 0.574 |
| 114 | 114 | 0.0108 |
| 115 | 115 | 0.204 |
| 116 | 116 | 0.0792 |
| 117 | 117 | 0.0681 |
| 118 | 118 | 0.0481 |
| 119 | 119 | 0.0381 |
| 12 | 12 | 0.834 |
| 120 | 120 | 0.744 |
| 121 | 121 | 0.94 |
| 122 | 122 | 0.583 |
| 123 | 123 | 0.436 |
| 124 | 124 | 0.448 |
| 125 | 125 | 0.319 |
| 126 | 126 | 0.607 |
| 127 | 127 | 0.283 |
| 128 | 128 | 0.578 |
| 129 | 129 | 0.346 |
| 13 | 13 | 0.164 |
| 130 | 130 | 0.103 |
| 131 | 131 | 0.104 |
| 132 | 132 | 0.345 |
| 133 | 133 | 0.87 |
| 134 | 134 | 0.459 |
| 135 | 135 | 0.838 |
| 136 | 136 | 0.721 |
| 137 | 137 | 0.692 |
| 138 | 138 | 0.629 |
| 139 | 139 | 0.0119 |
| 14 | 14 | 0.381 |
| 140 | 140 | 0.253 |
| 141 | 141 | 0.278 |
| 142 | 142 | 0.653 |
| 143 | 143 | 0.96 |
| 144 | 144 | 0.391 |
| 145 | 145 | 0.888 |
| 146 | 146 | 0.886 |
| 147 | 147 | 0.957 |
| 148 | 148 | 0.0278 |
| 149 | 149 | 0.044 |
| 15 | 15 | 0.623 |
| 150 | 150 | 0.84 |
| 151 | 151 | 0.47 |
| 152 | 152 | 0.639 |
| 153 | 153 | 0.602 |
| 154 | 154 | 0.926 |
| 155 | 155 | 0.0303 |
| 156 | 156 | 0.861 |
| 157 | 157 | 0.229 |
| 158 | 158 | 0.814 |
| 159 | 159 | 0.784 |
| 16 | 16 | 0.0776 |
| 160 | 160 | 0.352 |
| 161 | 161 | 0.439 |
| 162 | 162 | 0.881 |
| 163 | 163 | 0.753 |
| 164 | 164 | 0.148 |
| 165 | 165 | 0.589 |
| 166 | 166 | 0.064 |
| 167 | 167 | 0.28 |
| 168 | 168 | 0.686 |
| 169 | 169 | 0.0158 |
| 17 | 17 | 0.244 |
| 18 | 18 | 0.787 |
| 19 | 19 | 0.188 |
| 2 | 2 | 0.626 |
| 20 | 20 | 0.728 |
| 21 | 21 | 0.556 |
| 22 | 22 | 0.091 |
| 23 | 23 | 0.981 |
| 24 | 24 | 0.598 |
| 25 | 25 | 0.56 |
| 26 | 26 | 0.25 |
| 27 | 27 | 0.164 |
| 28 | 28 | 0.967 |
| 29 | 29 | 0.0808 |
| 3 | 3 | 0.0449 |
| 30 | 30 | 0.829 |
| 31 | 31 | 0.389 |
| 32 | 32 | 3.3313e-5 |
| 33 | 33 | 0.16 |
| 34 | 34 | 0.937 |
| 35 | 35 | 0.623 |
| 36 | 36 | 0.0285 |
| 37 | 37 | 0.0618 |
| 38 | 38 | 0.201 |
| 39 | 39 | 0.633 |
| 4 | 4 | 0.288 |
| 40 | 40 | 0.0243 |
| 41 | 41 | 0.533 |
| 42 | 42 | 0.724 |
| 43 | 43 | 0.117 |
| 44 | 44 | 0.00151 |
| 45 | 45 | 0.993 |
| 46 | 46 | 0.146 |
| 47 | 47 | 0.0335 |
| 48 | 48 | 0.104 |
| 49 | 49 | 0.184 |
| 5 | 5 | 0.609 |
| 50 | 50 | 0.861 |
| 51 | 51 | 0.551 |
| 52 | 52 | 0.666 |
| 53 | 53 | 0.54 |
| 54 | 54 | 0.681 |
| 55 | 55 | 0.974 |
| 56 | 56 | 0.305 |
| 57 | 57 | 0.624 |
| 58 | 58 | 0.361 |
| 59 | 59 | 0.124 |
| 6 | 6 | 0.549 |
| 60 | 60 | 0.269 |
| 61 | 61 | 0.588 |
| 62 | 62 | 0.365 |
| 63 | 63 | 0.219 |
| 64 | 64 | 0.0898 |
| 65 | 65 | 0.207 |
| 66 | 66 | 0.0565 |
| 67 | 67 | 0.794 |
| 68 | 68 | 0.577 |
| 69 | 69 | 0.471 |
| 7 | 7 | 0.384 |
| 70 | 70 | 3.30304e-4 |
| 71 | 71 | 0.0246 |
| 72 | 72 | 0.111 |
| 73 | 73 | 0.171 |
| 74 | 74 | 0.608 |
| 75 | 75 | 0.13 |
| 76 | 76 | 0.378 |
| 77 | 77 | 0.0442 |
| 78 | 78 | 0.655 |
| 79 | 79 | 0.0264 |
| 8 | 8 | 0.126 |
| 80 | 80 | 0.899 |
| 81 | 81 | 0.314 |
| 82 | 82 | 0.00322 |
| 83 | 83 | 0.404 |
| 84 | 84 | 0.275 |
| 85 | 85 | 0.0141 |
| 86 | 86 | 0.641 |
| 87 | 87 | 0.85 |
| 88 | 88 | 0.926 |
| 89 | 89 | 0.00808 |
| 9 | 9 | 0.77 |
| 90 | 90 | 0.966 |
| 91 | 91 | 0.443 |
| 92 | 92 | 0.0778 |
| 93 | 93 | 0.971 |
| 94 | 94 | 0.34 |
| 95 | 95 | 0.053 |
| 96 | 96 | 0.0695 |
| 97 | 97 | 0.316 |
| 98 | 98 | 0.234 |
| 99 | 99 | 0.579 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11279
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
DOID:3347 osteosarcoma
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0100407 osteosarcoma cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000055 (non-terminally differentiated cell)
0000003 (native cell)
0000548 (animal cell)
0002320 (connective tissue cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
0000062 (osteoblast)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
14566 (disease of cellular proliferation)
201 (connective tissue cancer)
0060100 (musculoskeletal system cancer)
3347 (osteosarcoma)
UBERON: Anatomy
0000468 (multi-cellular organism)
0001474 (bone element)
0002384 (connective tissue)
0000479 (tissue)
0000062 (organ)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0004765 (skeletal element)
0002204 (musculoskeletal system)
0001434 (skeletal system)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100385 (bone cancer cell line sample)
0100407 (osteosarcoma cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000335 (mesenchyme condensation cell)
