FF:10563-108A5: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005944 | ||
| | |accession_numbers=CAGE;DRX008032;DRR008904;DRZ000329;DRZ001714;DRZ011679;DRZ013064 | ||
| | |ancestors_in_anatomy_facet= | ||
| | |ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0002371,CL:0000542,CL:0000219,CL:0000945,CL:0000738,CL:0002087,CL:0002242,CL:0000255 | ||
|ancestors_in_disease_facet=DOID:4,DOID:630,DOID:0050177,DOID:0050427 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0101522 | |||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
| | |datafreeze_phase=2 | ||
| | |def= | ||
|expression_enrichment_score=chr11:111249993..111250006,-!p1@POU2AF1!2.84!698.20!POU2AF1;;chr6:391743..391759,+!p1@IRF4!2.78!602.35!IRF4;;chr16:85932760..85932775,+!p1@IRF8!2.35!223.44!IRF8;;chr2:68592406..68592424,+!p1@PLEK!2.26!181.12!PLEK;;chr1:25291475..25291511,-!p2@RUNX3!2.03!106.75!RUNX3;;chr19:50922187..50922204,+!p1@SPIB!1.97!92.32!SPIB;;chr19:36204309..36204335,+!p1@ZBTB32!1.96!89.76!ZBTB32;;chr19:19281060..19281078,-!p2@MEF2BNB-MEF2B,p2@MEF2B!1.90!77.58!MEF2B;;chr17:38020392..38020477,-!p1@IKZF3!1.87!73.73!IKZF3;;chr1:25256756..25256774,-!p1@RUNX3!1.69!87.19!RUNX3;;chr14:75988771..75988826,+!p1@BATF!1.67!60.59!BATF;;chr2:231090433..231090469,+!p1@SP140!1.66!44.88!SP140;;chr2:231090471..231090504,+!p2@SP140!1.65!43.92!SP140;;chr14:75988831..75988847,+!p2@BATF!1.59!37.51!BATF;;chr7:128577972..128578047,+!p1@IRF5!1.55!53.21!IRF5;;chr11:615570..615721,-!p2@IRF7!1.49!57.70!IRF7;;chr4:185395590..185395627,-!p3@IRF2!1.48!36.22!IRF2;;chr2:68592394..68592405,+!p2@PLEK!1.48!29.17!PLEK;;chr8:135577829..135577861,-!p6@ZFAT!1.47!28.21!ZFAT;;chr5:133450365..133450444,+!p1@TCF7!1.38!101.62!TCF7;;chr3:189349162..189349207,+!p2@TP63!1.38!22.76!TP63;;chr11:47400078..47400106,-!p1@SPI1!1.36!22.12!SPI1;;chr5:88178983..88179012,-!p1@MEF2C!1.35!162.21!MEF2C;;chr1:38512457..38512474,-!p1@POU3F1!1.33!22.12!POU3F1;;chr5:88120151..88120177,-!p6@MEF2C!1.32!19.88!MEF2C;;chr17:40440359..40440386,+!p4@STAT5A!1.31!19.23!STAT5A;;chr10:104155480..104155534,+!p2@NFKB2!1.26!109.31!NFKB2;;chr8:72756063..72756125,-!p1@MSC!1.23!32.06!MSC;;chr19:42636586..42636607,-!p1@POU2F2!1.22!42.64!POU2F2;;chr8:72756667..72756736,-!p2@MSC!1.22!24.36!MSC;;chr5:142780237..142780261,-!p7@NR3C1!1.22!15.71!NR3C1;;chr8:72756637..72756664,-!p3@MSC!1.21!17.31!MSC;;chr9:37034469..37034474,-!p1@PAX5!1.21!15.39!PAX5;;chr6:29648890..29648944,-!p1@ZFP57!1.18!14.11!ZFP57;;chr2:68615031..68615055,+!p3@PLEK!1.14!12.82!PLEK;;chr8:135614084..135614119,-!p4@ZFAT!1.12!12.18!ZFAT;;chr19:50432453..50432468,+!p1@ATF5!1.10!644.98!ATF5;;chr3:101546827..101546847,+!p2@NFKBIZ!1.10!16.35!NFKBIZ;;chr1:25291620..25291635,-!p4@RUNX3!1.09!11.22!RUNX3;;chr20:50159198..50159299,-!p1@NFATC2!1.08!16.03!NFATC2;;chr2:60778035..60778060,-!p4@BCL11A!1.08!13.14!BCL11A;;chr9:2015335..2015370,+!p1@SMARCA2!1.07!132.39!SMARCA2;;chr11:615942..615957,-!p1@IRF7!1.07!102.58!IRF7;;chr9:2015306..2015323,+!p3@SMARCA2!1.05!26.93!SMARCA2;;chr5:158526917..158526932,-!p1@EBF1!1.05!25.65!EBF1;;chr18:52989031..52989079,-!p2@TCF4!1.04!23.72!TCF4;;chr19:19729477..19729542,-!p1@PBX4!1.04!21.80!PBX4;;chr12:54785074..54785122,-!p2@ZNF385A!1.04!15.39!ZNF385A;;chr2:60780607..60780624,-!p2@BCL11A!1.03!30.45!BCL11A;;chr17:45810594..45810608,+!p1@TBX21!1.03!9.62!TBX21;;chr6:41700616..41700664,-!p8@TFEB!1.03!9.62!TFEB;;chr19:45579725..45579743,-!p1@ZNF296!1.02!43.92!ZNF296;;chr1:151319654..151319698,-!p2@RFX5!1.00!19.88!RFX5;;chr10:64576105..64576133,-!p1@EGR2!1.00!18.59!EGR2;;chr4:113437332..113437337,-!p1@NEUROG2!1.00!8.98!NEUROG2;;chr5:142780189..142780223,-!p6@NR3C1!1.00!8.98!NR3C1;;chr19:36391434..36391450,-!p1@NFKBID!0.99!17.63!NFKBID;;chr8:72756267..72756296,-!p4@MSC!0.99!13.14!MSC;;chr10:104154246..104154347,+!p3@NFKB2!0.98!53.53!NFKB2;;chr16:85936412..85936431,+!p2@IRF8!0.98!8.66!IRF8;;chr2:68615063..68615089,+!p4@PLEK!0.98!8.66!PLEK;;chr6:44233252..44233296,-!p1@NFKBIE!0.97!83.99!NFKBIE;;chr6:41673552..41673571,-!p10@TFEB!0.97!8.33!TFEB;;chr3:141103634..141103665,+!p18@ZBTB38!0.97!8.33!ZBTB38;;chr2:97202480..97202499,+!p1@ARID5A!0.94!80.14!ARID5A;;chr2:214015111..214015179,-!p1@IKZF2!0.94!14.11!IKZF2;;chr6:157098579..157098634,+!p4@ARID1B!0.93!17.63!ARID1B;;chr6:144385698..144385742,-!p2@PLAGL1!0.93!9.30!PLAGL1;;chr9:117150254..117150271,-!p1@AKNA!0.92!20.52!AKNA;;chr20:56195474..56195506,-!p1@ZBP1!0.92!7.37!ZBP1;;chr6:34204973..34204990,+!p4@HMGA1!0.91!99.38!HMGA1;;chr8:135614120..135614149,-!p5@ZFAT!0.91!7.05!ZFAT;;chr19:42627037..42627084,-!p3@POU2F2!0.91!7.05!POU2F2;;chr15:74833584..74833626,+!p1@ARID3B!0.90!16.67!ARID3B;;chr2:214013461..214013517,-!p6@IKZF2!0.89!6.73!IKZF2;;chr2:214015343..214015366,-!p3@IKZF2!0.89!6.73!IKZF2;;chr6:41701557..41701578,-!p3@TFEB!0.89!6.73!TFEB;;chr2:191878874..191878938,-!p1@STAT1!0.88!372.18!STAT1;;chr2:231084659..231084721,-!p1@SP110!0.87!157.08!SP110;;chr2:45168834..45168847,+!p2@SIX3!0.87!6.41!SIX3;;chr1:158979686..158979745,+!p1@IFI16!0.86!218.95!IFI16;;chr5:88179017..88179046,-!p2@MEF2C!0.86!26.29!MEF2C;;chr14:35873947..35873965,-!p1@NFKBIA!0.85!410.33!NFKBIA;;chr5:321810..321877,+!p1@AHRR!0.85!20.20!AHRR;;chr2:148778973..148779035,+!p3@MBD5!0.85!16.67!MBD5;;chr15:76629123..76629151,+!p1@ISL2!0.85!6.73!ISL2;;chr6:166581333..166581349,-!p2@T!0.85!6.09!T;;chr5:124084466..124084484,-!p6@ZNF608!0.83!5.77!ZNF608;;chr17:37934365..37934387,-!p2@IKZF3!0.83!5.77!IKZF3;;chr14:75988851..75988862,+!p3@BATF!0.81!5.45!BATF;;chr5:142779999..142780026,-!p20@NR3C1!0.81!5.45!NR3C1;;chr8:86099884..86099918,+!p4@E2F5!0.81!5.45!E2F5;;chr8:72756023..72756055,-!p6@MSC!0.80!6.73!MSC;;c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| | |ffid_belonging_in_development=CL:0000134,CL:0000051 | ||
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| | |||
| | |||
|fonse_cell_line=FF:0101522 | |fonse_cell_line=FF:0101522 | ||
|fonse_cell_line_closure=FF:0101522 | |fonse_cell_line_closure=FF:0101522 | ||
Line 66: | Line 40: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|top_motifs= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/xeroderma%2520pigentosum%2520b%2520cell%2520line%253aXPL%252017.CNhs11813.10563-108A5.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/xeroderma%2520pigentosum%2520b%2520cell%2520line%253aXPL%252017.CNhs11813.10563-108A5.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/xeroderma%2520pigentosum%2520b%2520cell%2520line%253aXPL%252017.CNhs11813.10563-108A5.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/xeroderma%2520pigentosum%2520b%2520cell%2520line%253aXPL%252017.CNhs11813.10563-108A5.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/xeroderma%2520pigentosum%2520b%2520cell%2520line%253aXPL%252017.CNhs11813.10563-108A5.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10563-108A5 | |||
|is_a=DOID:0050427;;EFO:0002091;;FF:0000210;;FF:0101522 | |||
|is_obsolete= | |||
|library_id=CNhs11813 | |||
|library_id_phase_based=2:CNhs11813 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10563 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10563 | |||
|name=xeroderma pigentosum b cell line:XPL 17 | |||
|namespace=FANTOM5 | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs11813,LSID829,release010,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0.107572416418003,0,0,0,0,0.350760063768453,0.12076093114532,-0.277153935884372,0.0873018642292285,0,0,0,0,0,0,0,0,0,0,0.83060360645577,0,0,0.0618218224875786,0,0,0,0,0.465889869901082,0.117186936567949,0,0,0.33293328012222,0,0,0,0,0,0,0,0,0,0,0,0,-0.150001178875484,0.0407424628766811,0,0,0,0,0,0,0,0.083357395305169,0,0,0,0.215144832836006,0,-0.0347351921300741,0,0.0237685699027144,0,0,-0.097343627213097,0,0,0,0,0,0,0,0,0.12076093114532,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0163554910672499,-0.261415547077318,0.179183888440657,0,0,0.102575621884661,0.0217475322546725,0,0,0.12076093114532,0,0.19459845335853,0.00783970149722275,0,0,0,0,0,0.06038046557266,0,0,0,0,0,0,0,0,0,0,0.12076093114532,-0.0359931283498012,0.12076093114532,0,0,-0.0405403851360124,-0.155868371561842,0,0,0.0932917284843835,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0.292633804596236,0.19459845335853,0,0,0,0.12076093114532,0.12076093114532,0.358367776881315,0,0,0,0,0,-0.247178875285564,0,-0.115718441870693,0.149118662072764,0.06038046557266,0.292633804596236,-0.015150263518372,0,0,0,0,0,0,0.12076093114532,0.12076093114532,0,-0.128119866952565,0,-0.0504125515893149,0,0,0,0,-0.0186252810838506,-0.090327398062401,0,-0.0279411588513918,-0.0683442610773682,0,0,0,0,0.0165156355243364,0,0.294568399196517,-0.0827201683234173,0,-0.508695342660655,0.0161706605565812,0,0,0,0.186002645736597,-0.0482747891279832,0,0,-0.121779851751874,0.403552896917211,0,0,-0.391044581551635,0,0.150096557834375,-0.0604397418968705,0,0.168706286540208,0,0,0,0,0,0,0,0,0,0,0,-0.0574934668214365,-0.034354792082733,0,0,0,0,0.0920206739025708,0,0,-0.373286155956567,-0.148357895203488,0,0.408574095884473,0,-0.181628795864594,-0.0128275972362828,0.0539947802526331,-0.164802034701074,-0.147401849371139,-0.189981719549847,0,-0.0780905873360953,-0.786272629114012,0.0424173320378287,0.375594870819351,-0.0878673931331223,-1.2314085082871,-0.0416772729085344,0,0.12076093114532,0,-0.25406569338259,0,-0.0239035894386903,-0.369353783331454,-0.125330458136706,-0.67098743647571,-0.735184081566308,-0.443655800889226,-0.110111555161767,-0.0395325284566706,-0.242291620060588,-0.019773733828388,-0.4215723249037,-0.168803189786527,0,-0.0877514257027229,-0.224646260083796,-0.196508068663958,0.383126688112855,-0.00266062216683693,0.105426576632384,-0.0683442610773682,0,-0.563540646996517,0.0654890573753153,0,-0.0727841703381182,-0.112887360970329,0,0,0.272784910092478,0,0,0.0706466075274701,0.311203175911756,-0.0177107287195385,0,-0.0526011586459985,0,0.0454424507641365,0,0.110983109194719,-0.081409830465486,0,0,0,0.002931603930426,-0.230771999047031,-0.164990696339003,0.043495064509345,0.680964022800516,-0.0172006597401058,0.304308393251406,0.102575621884661,-0.788939864790226,0.12076093114532,-0.0881268324752877,-0.210162025788965,-0.668399917682374,-0.679498131621524,-0.0909489830048511,-0.475957487811568,0,-0.256063937723677,0,-0.0827437664159719,0,0.471793255463039,-0.247799946877004,1.04944277402518,0.102931507875843,0,-0.0571932630603945,1.0945847825153,0,-0.151623442026661,-0.0418894659940428,0,-0.0296061521893198,-0.697695966512583,0.77095252242574,-0.138989456679195,0,-0.790080158389657,0,0,-0.211675399204543,0.353928000678976,0,0.143638387448803,0.15486312698434,0.0515228243316963,0.176662731161302,0.215144832836006,0,-0.645700337992725,0,0,-0.60592806381803,-0.0636048451378017,-0.261415547077318,0.597368977455166,0,-0.108622809454255,0,0.215144832836006,-0.177527765965176,0.55200445977108,0.0656609340490145,0,0,-0.103564394300706,0,0,0,0,0,0,0,0,0,0,0,0,0.120504267898989,-0.062199525620212,0,-0.0424533965657996,0,0,0,0,0,0,0,0,0.0109148508009205,-0.0683441541483374,-0.12301741567642,0,0,0.179183888440657,0,-0.094962471408155,-0.203236562094724,0.12076093114532,-0.0111017753523122,0,0.294702019221682,0,0,-0.0861409897892114,0,0,0,0.06038046557266,0.157414375782342,0.374282685469552,0,0.12076093114532,0,0.0156794029944455,0,0,0,0,0.0957994162843039,0,0,-0.403895825552602,0,0.157769413178702,-0.0815818795468414,0,0.254070716999347,0.0962964193469924,-0.17921673035454,0,0,0.0970206450914278,0,0,0.0277177397321096,0.000615660851900152,0,0,0,0,0,0,0,0.12076093114532,0.0783192921964803,0,0,0,0,0,0,0,0,0.12076093114532,0,0,-0.225425511542921,0.122920776177496,0,0,0,0,0,0,0,-0.0241060230789031,0.0413924747639775,0,0,0,0,0,0.12076093114532,0,0,0.184312925863749,0,0,0,0,0,0.0237685699027144,0,0,0,0.215144832836006,0.174603728458457,0,0,-0.277362132193514,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0918257468005585,-0.277153935884372,0,0.12076093114532,0,0,0,0.12076093114532,0,0.0835344786752249,0,0,0,0,0.101260459127029,0,0,0,-0.104796384789156,0,0.350760063768453,0,0.12076093114532,0.12076093114532,0,0,0,0.107572416418003,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.132670143600935,0,-0.0624577274708851,0,0,0,-0.232628352633041,0,0,0,0,0,0,0.076231992389476,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.12076093114532,0,0,0,0,0,0.146316902298118,0.0376477957404234,0,0,0,0,0,0,0,0.117186936567949,0,0,0.233467980938249,0,0,0,0,0,0,0.137370818814252,-0.283220399823148,-0.0762179249796087,0,0,0,0.00599489309020475,0.215144832836006,0,-0.0365653648937095,0,-0.0667773874189013,0.215144832836006,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0618218224875786,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.06038046557266,0,0,0,0,0,0,-0.0340113632754165,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0407424628766811,0,0,0,-0.213086229657044,0,0,0,0,0,0,0.12076093114532,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.190284034114388,0,0,0,0,0,0,0,0,0,0,0,0,0,0.166922757596952,0,0.273991144651288,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.12076093114532,0.188906807096629,0,0,0,0,0.0731238204844007,0,0.06038046557266,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.06038046557266,0.83060360645577,0,0.212279261612577,0,0,-0.1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| |||
|rna_box=108 | |||
|rna_catalog_number= | |||
|rna_concentration=2.03171 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=2.11 | |||
|rna_od260/280=2.1 | |||
|rna_position=A5 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=108A5 | |||
|rna_weight_ug=71.10985 | |||
|sample_age= | |||
|sample_category=cell lines | |||
|sample_cell_catalog=RCB2286 | |||
|sample_cell_line=XPL 17 | |||
|sample_cell_lot= | |||
|sample_cell_type=b cell | |||
|sample_collaboration=Yukio Nakamura (RIKEN BRC) | |||
|sample_company=RIKEN Bioresource centre | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=xeroderma pigentosum | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;6.89731291323638e-257!GO:0043227;membrane-bound organelle;1.47602913130198e-216!GO:0043231;intracellular membrane-bound organelle;3.41315359984354e-216!GO:0043226;organelle;3.43748975720541e-212!GO:0043229;intracellular organelle;2.16686521039902e-211!GO:0005737;cytoplasm;1.10962408695004e-188!GO:0044422;organelle part;1.32291241864354e-148!GO:0044446;intracellular organelle part;1.20807885254649e-146!GO:0044444;cytoplasmic part;5.46013997808856e-129!GO:0032991;macromolecular complex;1.62428527059227e-111!GO:0044237;cellular metabolic process;5.26989982569517e-103!GO:0044238;primary metabolic process;1.48428419595497e-100!GO:0030529;ribonucleoprotein complex;1.31192757478102e-96!GO:0005634;nucleus;8.43797409237964e-95!GO:0043170;macromolecule metabolic process;3.70391160656187e-92!GO:0005739;mitochondrion;1.46461260580249e-85!GO:0003723;RNA binding;8.86108688526648e-85!GO:0044428;nuclear part;1.90317856965395e-83!GO:0043233;organelle lumen;5.96822070872478e-83!GO:0031974;membrane-enclosed lumen;5.96822070872478e-83!GO:0005515;protein binding;6.52902169533238e-69!GO:0006412;translation;1.33897915620147e-65!GO:0044429;mitochondrial part;1.68425508944268e-59!GO:0043283;biopolymer metabolic process;4.91794993368702e-58!GO:0006396;RNA processing;1.89940084434717e-57!GO:0005840;ribosome;1.03928786830004e-56!GO:0043234;protein complex;5.15285834880531e-56!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.84590646366974e-53!GO:0010467;gene expression;5.03002834019647e-53!GO:0031967;organelle envelope;1.01273036163908e-50!GO:0031975;envelope;2.67533173324989e-50!GO:0019538;protein metabolic process;4.44654888232853e-50!GO:0031981;nuclear lumen;1.1880657731109e-49!GO:0003735;structural constituent of ribosome;1.59569766845176e-49!GO:0044249;cellular biosynthetic process;6.40421045512035e-49!GO:0031090;organelle membrane;1.48606721878142e-48!GO:0009058;biosynthetic process;2.83112291272926e-47!GO:0016071;mRNA metabolic process;2.64823708858295e-45!GO:0044267;cellular protein metabolic process;3.0323691004245e-45!GO:0033036;macromolecule localization;3.20191672770728e-45!GO:0044260;cellular macromolecule metabolic process;4.63135209569115e-45!GO:0009059;macromolecule biosynthetic process;9.31288349527578e-45!GO:0033279;ribosomal subunit;2.99677471627846e-43!GO:0015031;protein transport;4.02556217767379e-43!GO:0045184;establishment of protein localization;7.35028809925314e-42!GO:0005829;cytosol;8.11178639910096e-42!GO:0008104;protein localization;1.28121323891144e-41!GO:0008380;RNA splicing;8.62340882695164e-40!GO:0006397;mRNA processing;9.06393877511414e-39!GO:0016043;cellular component organization and biogenesis;9.99535984789311e-38!GO:0005740;mitochondrial envelope;1.02345709395568e-36!GO:0046907;intracellular transport;1.42015861585079e-36!GO:0006259;DNA metabolic process;6.53814437836949e-36!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.87323474656881e-34!GO:0006996;organelle organization and biogenesis;7.10077397812209e-34!GO:0031966;mitochondrial membrane;1.01704408775006e-33!GO:0065003;macromolecular complex assembly;3.90972525578958e-33!GO:0019866;organelle inner membrane;5.32566470287905e-33!GO:0003676;nucleic acid binding;8.43261192461505e-33!GO:0006886;intracellular protein transport;5.01155917526696e-32!GO:0000166;nucleotide binding;7.56454613659258e-32!GO:0043228;non-membrane-bound organelle;5.81849566312863e-31!GO:0043232;intracellular non-membrane-bound organelle;5.81849566312863e-31!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.09088428576811e-30!GO:0005743;mitochondrial inner membrane;1.74310420659794e-30!GO:0005654;nucleoplasm;4.45606748189633e-30!GO:0005681;spliceosome;7.28687445466607e-30!GO:0022607;cellular component assembly;6.90742461306901e-29!GO:0044445;cytosolic part;3.49217519216877e-28!GO:0051649;establishment of cellular localization;1.07299230413121e-27!GO:0051641;cellular localization;2.70467698884437e-27!GO:0031980;mitochondrial lumen;1.11338346745337e-26!GO:0005759;mitochondrial matrix;1.11338346745337e-26!GO:0007049;cell cycle;3.7544477464043e-26!GO:0012501;programmed cell death;2.80637651503562e-25!GO:0006915;apoptosis;3.00846437086343e-25!GO:0016070;RNA metabolic process;4.07741859603888e-24!GO:0006119;oxidative phosphorylation;1.00974127762208e-23!GO:0032553;ribonucleotide binding;1.16332290891501e-23!GO:0032555;purine ribonucleotide binding;1.16332290891501e-23!GO:0017076;purine nucleotide binding;2.45872070297478e-23!GO:0044455;mitochondrial membrane part;4.67829811029086e-23!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;4.78504193951782e-23!GO:0016462;pyrophosphatase activity;4.99720746720409e-23!GO:0016817;hydrolase activity, acting on acid anhydrides;6.42646546936109e-23!GO:0017111;nucleoside-triphosphatase activity;1.10167595615748e-22!GO:0044451;nucleoplasm part;1.10201364272053e-22!GO:0044265;cellular macromolecule catabolic process;2.26558540208268e-22!GO:0015934;large ribosomal subunit;2.5345537681762e-22!GO:0006974;response to DNA damage stimulus;2.71854354733564e-22!GO:0008219;cell death;3.71374982047382e-22!GO:0016265;death;3.71374982047382e-22!GO:0015935;small ribosomal subunit;4.48031533812046e-22!GO:0006512;ubiquitin cycle;7.74305844279185e-22!GO:0005730;nucleolus;3.42296193692611e-21!GO:0022402;cell cycle process;4.10507195141735e-21!GO:0016874;ligase activity;1.74073873304249e-20!GO:0005524;ATP binding;2.3776155442282e-19!GO:0044248;cellular catabolic process;2.5537189473847e-19!GO:0005746;mitochondrial respiratory chain;7.78919057669551e-19!GO:0022618;protein-RNA complex assembly;9.05675338513409e-19!GO:0032559;adenyl ribonucleotide binding;9.09819922658157e-19!GO:0006281;DNA repair;1.43867516462818e-18!GO:0008134;transcription factor binding;1.60192067213316e-18!GO:0009057;macromolecule catabolic process;2.14588681624065e-18!GO:0030554;adenyl nucleotide binding;2.61021976901132e-18!GO:0005694;chromosome;2.89115798120298e-18!GO:0043285;biopolymer catabolic process;3.83072788475971e-18!GO:0006457;protein folding;4.20405891493542e-18!GO:0042981;regulation of apoptosis;6.16030451078743e-18!GO:0051186;cofactor metabolic process;6.16030451078743e-18!GO:0043067;regulation of programmed cell death;1.05313851411119e-17!GO:0000278;mitotic cell cycle;1.36096720898195e-17!GO:0000502;proteasome complex (sensu Eukaryota);1.45472124482622e-17!GO:0019941;modification-dependent protein catabolic process;2.06109418907176e-17!GO:0043632;modification-dependent macromolecule catabolic process;2.06109418907176e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;2.16769853659141e-17!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;2.2463691362902e-17!GO:0006511;ubiquitin-dependent protein catabolic process;5.30472352919678e-17!GO:0044257;cellular protein catabolic process;6.22391464594376e-17!GO:0012505;endomembrane system;7.4807853810319e-17!GO:0006605;protein targeting;7.86131388380312e-17!GO:0005761;mitochondrial ribosome;8.16283306268403e-17!GO:0000313;organellar ribosome;8.16283306268403e-17!GO:0044427;chromosomal part;1.32196694705688e-16!GO:0050136;NADH dehydrogenase (quinone) activity;1.4473549918705e-16!GO:0003954;NADH dehydrogenase activity;1.4473549918705e-16!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.4473549918705e-16!GO:0051276;chromosome organization and biogenesis;1.89236758884451e-16!GO:0042254;ribosome biogenesis and assembly;4.09207134404831e-16!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);5.33960730007192e-16!GO:0043412;biopolymer modification;5.56234857795049e-16!GO:0005635;nuclear envelope;2.47657959604724e-15!GO:0008135;translation factor activity, nucleic acid binding;2.68798638728358e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);2.69901013418667e-15!GO:0005783;endoplasmic reticulum;3.57345486050744e-15!GO:0022403;cell cycle phase;3.932801299739e-15!GO:0016604;nuclear body;4.62131114271939e-15!GO:0000398;nuclear mRNA splicing, via spliceosome;5.77890155700207e-15!GO:0000375;RNA splicing, via transesterification reactions;5.77890155700207e-15!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;5.77890155700207e-15!GO:0042775;organelle ATP synthesis coupled electron transport;5.99101579244231e-15!GO:0042773;ATP synthesis coupled electron transport;5.99101579244231e-15!GO:0030964;NADH dehydrogenase complex (quinone);1.58971354895334e-14!GO:0045271;respiratory chain complex I;1.58971354895334e-14!GO:0005747;mitochondrial respiratory chain complex I;1.58971354895334e-14!GO:0007067;mitosis;1.80644694403231e-14!GO:0000087;M phase of mitotic cell cycle;2.07007423584304e-14!GO:0009719;response to endogenous stimulus;2.38411651815268e-14!GO:0048770;pigment granule;2.5104697778291e-14!GO:0042470;melanosome;2.5104697778291e-14!GO:0006732;coenzyme metabolic process;2.60139139733206e-14!GO:0006913;nucleocytoplasmic transport;3.01703687345956e-14!GO:0016887;ATPase activity;4.31823265532918e-14!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;5.17298165749577e-14!GO:0031965;nuclear membrane;5.35418403007029e-14!GO:0051169;nuclear transport;6.41813201186944e-14!GO:0006464;protein modification process;6.92786279781626e-14!GO:0042623;ATPase activity, coupled;8.44082401534588e-14!GO:0043687;post-translational protein modification;9.63411358230739e-14!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;9.69566860172751e-14!GO:0030163;protein catabolic process;3.81605680783204e-13!GO:0000279;M phase;5.45980695346616e-13!GO:0051082;unfolded protein binding;7.64978427335442e-13!GO:0006325;establishment and/or maintenance of chromatin architecture;8.91063821260297e-13!GO:0051301;cell division;1.33223580745398e-12!GO:0006260;DNA replication;1.37125535630331e-12!GO:0004386;helicase activity;3.27837350299285e-12!GO:0006323;DNA packaging;3.39248457742347e-12!GO:0051726;regulation of cell cycle;3.54766510626396e-12!GO:0044453;nuclear membrane part;4.76684230530336e-12!GO:0044432;endoplasmic reticulum part;5.25516240396335e-12!GO:0000074;regulation of progression through cell cycle;5.36894564453754e-12!GO:0003712;transcription cofactor activity;7.16042712161354e-12!GO:0006399;tRNA metabolic process;7.30761989322993e-12!GO:0006413;translational initiation;7.59234951928647e-12!GO:0009615;response to virus;1.2483844951757e-11!GO:0006446;regulation of translational initiation;1.78397075138008e-11!GO:0006333;chromatin assembly or disassembly;3.21700118005298e-11!GO:0003743;translation initiation factor activity;3.45697568755901e-11!GO:0048193;Golgi vesicle transport;3.49070920009103e-11!GO:0017038;protein import;3.49962855453941e-11!GO:0009056;catabolic process;3.57162379700899e-11!GO:0006364;rRNA processing;3.83710663507797e-11!GO:0016607;nuclear speck;4.12623158201873e-11!GO:0007249;I-kappaB kinase/NF-kappaB cascade;4.74688391513794e-11!GO:0009055;electron carrier activity;5.17048699990019e-11!GO:0016072;rRNA metabolic process;6.64600016358211e-11!GO:0009259;ribonucleotide metabolic process;8.28966276316469e-11!GO:0006163;purine nucleotide metabolic process;8.42482068253185e-11!GO:0006916;anti-apoptosis;1.16577422784407e-10!GO:0008026;ATP-dependent helicase activity;1.22070767639748e-10!GO:0006164;purine nucleotide biosynthetic process;1.22070767639748e-10!GO:0065002;intracellular protein transport across a membrane;1.25400564643378e-10!GO:0008639;small protein conjugating enzyme activity;1.34906413915654e-10!GO:0051188;cofactor biosynthetic process;1.51948899552358e-10!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;1.66316633742692e-10!GO:0005643;nuclear pore;1.69816553052768e-10!GO:0000785;chromatin;1.95667778245774e-10!GO:0050794;regulation of cellular process;2.22443185787811e-10!GO:0004842;ubiquitin-protein ligase activity;2.37305358756919e-10!GO:0009260;ribonucleotide biosynthetic process;2.37688009684636e-10!GO:0051246;regulation of protein metabolic process;2.38016672126254e-10!GO:0019787;small conjugating protein ligase activity;3.29782216055009e-10!GO:0065004;protein-DNA complex assembly;4.91148566381555e-10!GO:0009150;purine ribonucleotide metabolic process;5.14586141954132e-10!GO:0050657;nucleic acid transport;7.20578296928108e-10!GO:0051236;establishment of RNA localization;7.20578296928108e-10!GO:0050658;RNA transport;7.20578296928108e-10!GO:0009152;purine ribonucleotide biosynthetic process;7.41639763353823e-10!GO:0006403;RNA localization;8.5743912309542e-10!GO:0005794;Golgi apparatus;9.92194543689551e-10!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.00491277638501e-09!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;1.01645072879088e-09!GO:0015078;hydrogen ion transmembrane transporter activity;1.01667860824734e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.10145981196289e-09!GO:0016192;vesicle-mediated transport;1.13734407912754e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.14884764398322e-09!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.15681722634695e-09!GO:0004812;aminoacyl-tRNA ligase activity;1.15681722634695e-09!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.15681722634695e-09!GO:0007243;protein kinase cascade;1.18340152977788e-09!GO:0007005;mitochondrion organization and biogenesis;1.22017333575088e-09!GO:0005789;endoplasmic reticulum membrane;1.24463117865196e-09!GO:0043038;amino acid activation;1.52008886782303e-09!GO:0006418;tRNA aminoacylation for protein translation;1.52008886782303e-09!GO:0043039;tRNA aminoacylation;1.52008886782303e-09!GO:0043069;negative regulation of programmed cell death;1.5719207613707e-09!GO:0043066;negative regulation of apoptosis;1.91483590015146e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;2.67534239676462e-09!GO:0030532;small nuclear ribonucleoprotein complex;2.91029037460468e-09!GO:0043065;positive regulation of apoptosis;2.91195302834259e-09!GO:0009060;aerobic respiration;3.62026020691133e-09!GO:0008565;protein transporter activity;3.66572316896078e-09!GO:0016779;nucleotidyltransferase activity;4.29291852825179e-09!GO:0043068;positive regulation of programmed cell death;4.61760734861912e-09!GO:0046930;pore complex;6.29727401917093e-09!GO:0006461;protein complex assembly;7.03139770745474e-09!GO:0006793;phosphorus metabolic process;7.68181149268481e-09!GO:0006796;phosphate metabolic process;7.68181149268481e-09!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;8.70004408929826e-09!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;9.9564238618367e-09!GO:0006917;induction of apoptosis;1.05407978253925e-08!GO:0003697;single-stranded DNA binding;1.32236671800387e-08!GO:0005839;proteasome core complex (sensu Eukaryota);1.48176193684115e-08!GO:0016787;hydrolase activity;1.6519205128878e-08!GO:0016881;acid-amino acid ligase activity;1.71312305705443e-08!GO:0012502;induction of programmed cell death;1.84593960463369e-08!GO:0009108;coenzyme biosynthetic process;2.28319870933413e-08!GO:0051028;mRNA transport;2.69191593927301e-08!GO:0045333;cellular respiration;2.71493597293468e-08!GO:0019829;cation-transporting ATPase activity;2.71493597293468e-08!GO:0015986;ATP synthesis coupled proton transport;2.99463443460888e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;2.99463443460888e-08!GO:0005768;endosome;3.02573466366868e-08!GO:0016310;phosphorylation;4.33177522045713e-08!GO:0043566;structure-specific DNA binding;4.45953978127348e-08!GO:0016568;chromatin modification;4.61685186538394e-08!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;5.04887210168869e-08!GO:0009117;nucleotide metabolic process;5.36892376308456e-08!GO:0030120;vesicle coat;6.48235291676671e-08!GO:0030662;coated vesicle membrane;6.48235291676671e-08!GO:0006366;transcription from RNA polymerase II promoter;6.65271058470551e-08!GO:0003924;GTPase activity;7.25749493473744e-08!GO:0051170;nuclear import;8.32173729397179e-08!GO:0004298;threonine endopeptidase activity;9.17903475955635e-08!GO:0009142;nucleoside triphosphate biosynthetic process;9.21372424662944e-08!GO:0009201;ribonucleoside triphosphate biosynthetic process;9.21372424662944e-08!GO:0019899;enzyme binding;1.06406736255181e-07!GO:0016740;transferase activity;1.2020435039076e-07!GO:0009199;ribonucleoside triphosphate metabolic process;1.41870970860486e-07!GO:0006099;tricarboxylic acid cycle;1.52421746180836e-07!GO:0046356;acetyl-CoA catabolic process;1.52421746180836e-07!GO:0005525;GTP binding;1.53551287802464e-07!GO:0009141;nucleoside triphosphate metabolic process;1.55141388459592e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;1.6013616026774e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;1.6013616026774e-07!GO:0015077;monovalent inorganic cation transmembrane transporter activity;1.67451808499406e-07!GO:0006888;ER to Golgi vesicle-mediated transport;1.78167670791812e-07!GO:0006606;protein import into nucleus;1.92534269591385e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.41654482105381e-07!GO:0009144;purine nucleoside triphosphate metabolic process;2.41654482105381e-07!GO:0006334;nucleosome assembly;2.51698778309041e-07!GO:0051187;cofactor catabolic process;2.7555030597141e-07!GO:0006084;acetyl-CoA metabolic process;3.04076792957407e-07!GO:0006754;ATP biosynthetic process;3.31935367579394e-07!GO:0006753;nucleoside phosphate metabolic process;3.31935367579394e-07!GO:0031497;chromatin assembly;3.38406187166805e-07!GO:0045259;proton-transporting ATP synthase complex;3.45883172277441e-07!GO:0048475;coated membrane;3.53796662606705e-07!GO:0030117;membrane coat;3.53796662606705e-07!GO:0003713;transcription coactivator activity;3.7939374098169e-07!GO:0005770;late endosome;4.0213587956149e-07!GO:0006417;regulation of translation;4.4855359569368e-07!GO:0016469;proton-transporting two-sector ATPase complex;5.36455999575806e-07!GO:0005773;vacuole;5.81164204318773e-07!GO:0048523;negative regulation of cellular process;6.3646720843818e-07!GO:0006752;group transfer coenzyme metabolic process;6.3646720843818e-07!GO:0000323;lytic vacuole;7.29499227263547e-07!GO:0005764;lysosome;7.29499227263547e-07!GO:0046034;ATP metabolic process;7.30576016939306e-07!GO:0006261;DNA-dependent DNA replication;8.42947185600687e-07!GO:0009109;coenzyme catabolic process;9.8778994777961e-07!GO:0050789;regulation of biological process;9.94402454238126e-07!GO:0016772;transferase activity, transferring phosphorus-containing groups;1.01023577642614e-06!GO:0005793;ER-Golgi intermediate compartment;1.17633130375389e-06!GO:0048522;positive regulation of cellular process;1.19391161607695e-06!GO:0032446;protein modification by small protein conjugation;1.32961028431751e-06!GO:0019222;regulation of metabolic process;1.62288577810651e-06!GO:0000245;spliceosome assembly;2.65342789869409e-06!GO:0009165;nucleotide biosynthetic process;2.92509218475056e-06!GO:0016567;protein ubiquitination;2.92923533305503e-06!GO:0032561;guanyl ribonucleotide binding;3.70154944352816e-06!GO:0019001;guanyl nucleotide binding;3.70154944352816e-06!GO:0016563;transcription activator activity;4.02306135901888e-06!GO:0016491;oxidoreductase activity;4.38857972785911e-06!GO:0005762;mitochondrial large ribosomal subunit;4.40432232299864e-06!GO:0000315;organellar large ribosomal subunit;4.40432232299864e-06!GO:0031326;regulation of cellular biosynthetic process;6.895439163192e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;8.29834249310666e-06!GO:0065009;regulation of a molecular function;9.27809236375224e-06!GO:0003724;RNA helicase activity;9.38576911298202e-06!GO:0006401;RNA catabolic process;1.00579021284965e-05!GO:0048519;negative regulation of biological process;1.30741973468006e-05!GO:0009967;positive regulation of signal transduction;1.33669953461553e-05!GO:0006613;cotranslational protein targeting to membrane;1.43508413406905e-05!GO:0000314;organellar small ribosomal subunit;1.43775005813966e-05!GO:0005763;mitochondrial small ribosomal subunit;1.43775005813966e-05!GO:0003899;DNA-directed RNA polymerase activity;1.55924925295537e-05!GO:0051168;nuclear export;1.57107614336272e-05!GO:0005798;Golgi-associated vesicle;1.7637009917567e-05!GO:0008632;apoptotic program;2.03698344582912e-05!GO:0006310;DNA recombination;2.09174854974406e-05!GO:0015630;microtubule cytoskeleton;2.44640579836817e-05!GO:0007006;mitochondrial membrane organization and biogenesis;2.64654490701243e-05!GO:0045786;negative regulation of progression through cell cycle;2.70457531010698e-05!GO:0006091;generation of precursor metabolites and energy;2.71667667788101e-05!GO:0005819;spindle;3.23383819819811e-05!GO:0044440;endosomal part;3.74796021938294e-05!GO:0010008;endosome membrane;3.74796021938294e-05!GO:0043623;cellular protein complex assembly;3.87249418631357e-05!GO:0005741;mitochondrial outer membrane;4.14764796475818e-05!GO:0016564;transcription repressor activity;4.2265148795698e-05!GO:0005813;centrosome;4.74841401222229e-05!GO:0043021;ribonucleoprotein binding;5.32820809879771e-05!GO:0006839;mitochondrial transport;5.52252029873317e-05!GO:0000151;ubiquitin ligase complex;5.54590623268347e-05!GO:0030658;transport vesicle membrane;5.67089876964871e-05!GO:0031968;organelle outer membrane;5.78260122843732e-05!GO:0048518;positive regulation of biological process;5.99374072568047e-05!GO:0031323;regulation of cellular metabolic process;6.6980866633666e-05!GO:0031072;heat shock protein binding;8.2659993797755e-05!GO:0009889;regulation of biosynthetic process;8.76890404695321e-05!GO:0051427;hormone receptor binding;8.99604793936591e-05!GO:0019867;outer membrane;9.1693873728735e-05!GO:0008094;DNA-dependent ATPase activity;9.72859992393676e-05!GO:0043681;protein import into mitochondrion;9.88434286816982e-05!GO:0003714;transcription corepressor activity;0.000105462339451658!GO:0005815;microtubule organizing center;0.00010928958553829!GO:0005667;transcription factor complex;0.00011197818685027!GO:0016853;isomerase activity;0.000113128130996283!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00011676832836502!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000118758463832924!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000124857675963557!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000150209188832115!GO:0015399;primary active transmembrane transporter activity;0.000150209188832115!GO:0005657;replication fork;0.000152980442337629!GO:0035257;nuclear hormone receptor binding;0.000182238630156517!GO:0007088;regulation of mitosis;0.000183460932803269!GO:0005885;Arp2/3 protein complex;0.000183762031572177!GO:0008186;RNA-dependent ATPase activity;0.000186018438166442!GO:0000075;cell cycle checkpoint;0.000192074970275316!GO:0051325;interphase;0.000196952634188902!GO:0006402;mRNA catabolic process;0.000198169294287843!GO:0016126;sterol biosynthetic process;0.000200021317274091!GO:0000786;nucleosome;0.000207543574733696!GO:0000775;chromosome, pericentric region;0.000208155856534025!GO:0030660;Golgi-associated vesicle membrane;0.000209124900642313!GO:0006626;protein targeting to mitochondrion;0.000241032275380596!GO:0007242;intracellular signaling cascade;0.000253859552817905!GO:0007051;spindle organization and biogenesis;0.000262821872205056!GO:0008654;phospholipid biosynthetic process;0.000263692058533188!GO:0019752;carboxylic acid metabolic process;0.000265534826818233!GO:0051252;regulation of RNA metabolic process;0.000280269572469511!GO:0003678;DNA helicase activity;0.000336018201342359!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000340839510287736!GO:0006612;protein targeting to membrane;0.000348340480513726!GO:0051329;interphase of mitotic cell cycle;0.000355275722297485!GO:0006082;organic acid metabolic process;0.000364692208581592!GO:0005048;signal sequence binding;0.000375791843802877!GO:0051789;response to protein stimulus;0.000421819239803724!GO:0006986;response to unfolded protein;0.000421819239803724!GO:0008033;tRNA processing;0.000427444270185348!GO:0016363;nuclear matrix;0.000479849320855313!GO:0016741;transferase activity, transferring one-carbon groups;0.000480880979390828!GO:0031324;negative regulation of cellular metabolic process;0.000499248166567053!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000524583954711079!GO:0044452;nucleolar part;0.000536754033557591!GO:0003684;damaged DNA binding;0.000541666725271834!GO:0004004;ATP-dependent RNA helicase activity;0.000547342830838849!GO:0045454;cell redox homeostasis;0.000547342830838849!GO:0048468;cell development;0.000552599935662918!GO:0008637;apoptotic mitochondrial changes;0.00062206888587005!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000634240498245955!GO:0003729;mRNA binding;0.000653550725961587!GO:0022890;inorganic cation transmembrane transporter activity;0.000661305023689162!GO:0006302;double-strand break repair;0.000665348685288846!GO:0005758;mitochondrial intermembrane space;0.000699344276268938!GO:0051223;regulation of protein transport;0.000701828409707747!GO:0004527;exonuclease activity;0.000708903906792816!GO:0046483;heterocycle metabolic process;0.000712640094716228!GO:0015992;proton transport;0.000730449791741086!GO:0003725;double-stranded RNA binding;0.000734900554122764!GO:0006414;translational elongation;0.000754447630692746!GO:0046822;regulation of nucleocytoplasmic transport;0.00076047908949711!GO:0044431;Golgi apparatus part;0.000796188061157097!GO:0005774;vacuolar membrane;0.000796188061157097!GO:0051052;regulation of DNA metabolic process;0.000806111107518871!GO:0004518;nuclease activity;0.000832950548171274!GO:0043488;regulation of mRNA stability;0.000839733833435442!GO:0043487;regulation of RNA stability;0.000839733833435442!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000850913221286877!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000850913221286877!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000850913221286877!GO:0008168;methyltransferase activity;0.000858293020878872!GO:0031902;late endosome membrane;0.00087681084439809!GO:0006818;hydrogen transport;0.000892193302794475!GO:0065007;biological regulation;0.000899450858841461!GO:0031252;leading edge;0.00092152832800401!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000929552339045879!GO:0006891;intra-Golgi vesicle-mediated transport;0.000933895615023044!GO:0016859;cis-trans isomerase activity;0.000943430076232572!GO:0005684;U2-dependent spliceosome;0.000953271110288292!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.000982797041857942!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.000982797041857942!GO:0006383;transcription from RNA polymerase III promoter;0.000982854098412132!GO:0006350;transcription;0.000995687481773172!GO:0030880;RNA polymerase complex;0.00101695364638386!GO:0000776;kinetochore;0.00108451578433259!GO:0042113;B cell activation;0.00109563932682457!GO:0000049;tRNA binding;0.00111115918118374!GO:0004674;protein serine/threonine kinase activity;0.00111442823580073!GO:0006520;amino acid metabolic process;0.00118395756198792!GO:0048471;perinuclear region of cytoplasm;0.00122023678901484!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.00128904023469094!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00129443433227837!GO:0016251;general RNA polymerase II transcription factor activity;0.00130937096850809!GO:0006352;transcription initiation;0.00132486675200872!GO:0043492;ATPase activity, coupled to movement of substances;0.00141606761789946!GO:0015980;energy derivation by oxidation of organic compounds;0.00142971123752482!GO:0003690;double-stranded DNA binding;0.00144864727132746!GO:0006611;protein export from nucleus;0.00144864727132746!GO:0010468;regulation of gene expression;0.0014785378532044!GO:0007059;chromosome segregation;0.00161526605858934!GO:0005765;lysosomal membrane;0.00162318924046431!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.001638784148243!GO:0006007;glucose catabolic process;0.00164095197474204!GO:0006950;response to stress;0.00164401307228809!GO:0006695;cholesterol biosynthetic process;0.00173450457229192!GO:0008047;enzyme activator activity;0.00177334014326281!GO:0030867;rough endoplasmic reticulum membrane;0.00177334014326281!GO:0031988;membrane-bound vesicle;0.00177757126915448!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0018347055301686!GO:0015002;heme-copper terminal oxidase activity;0.0018347055301686!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0018347055301686!GO:0004129;cytochrome-c oxidase activity;0.0018347055301686!GO:0046649;lymphocyte activation;0.00194256580665278!GO:0048500;signal recognition particle;0.00198378107371795!GO:0046966;thyroid hormone receptor binding;0.00200994169768788!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.0020113411938835!GO:0044437;vacuolar part;0.00201245010827357!GO:0019904;protein domain specific binding;0.00202210631718666!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00205192203972915!GO:0000428;DNA-directed RNA polymerase complex;0.00205192203972915!GO:0031970;organelle envelope lumen;0.00205980140247431!GO:0050790;regulation of catalytic activity;0.00210646768123634!GO:0051920;peroxiredoxin activity;0.00221734092910356!GO:0005769;early endosome;0.00221875481925279!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00222626047774528!GO:0031982;vesicle;0.00224639752436097!GO:0030384;phosphoinositide metabolic process;0.00226224803572229!GO:0051092;activation of NF-kappaB transcription factor;0.00238294814292277!GO:0016197;endosome transport;0.00244748051112998!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00276464409806264!GO:0005637;nuclear inner membrane;0.00293619303739959!GO:0009124;nucleoside monophosphate biosynthetic process;0.00302132527489175!GO:0009123;nucleoside monophosphate metabolic process;0.00302132527489175!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00307517618326158!GO:0033116;ER-Golgi intermediate compartment membrane;0.00312764893027181!GO:0006778;porphyrin metabolic process;0.00312764893027181!GO:0033013;tetrapyrrole metabolic process;0.00312764893027181!GO:0016272;prefoldin complex;0.00314974705549227!GO:0004532;exoribonuclease activity;0.00325548528066906!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00325548528066906!GO:0007093;mitotic cell cycle checkpoint;0.0033315324000024!GO:0030133;transport vesicle;0.00347481519846401!GO:0008139;nuclear localization sequence binding;0.00367589068407271!GO:0016023;cytoplasmic membrane-bound vesicle;0.0036956300350643!GO:0032508;DNA duplex unwinding;0.00371808586967607!GO:0032392;DNA geometric change;0.00371808586967607!GO:0030118;clathrin coat;0.00378749187268473!GO:0042802;identical protein binding;0.00379729036921843!GO:0006650;glycerophospholipid metabolic process;0.00382976918349323!GO:0006595;polyamine metabolic process;0.00398159162089018!GO:0030127;COPII vesicle coat;0.00421952364389844!GO:0012507;ER to Golgi transport vesicle membrane;0.00421952364389844!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00430815189938448!GO:0045047;protein targeting to ER;0.00430815189938448!GO:0005788;endoplasmic reticulum lumen;0.0043221528115138!GO:0051235;maintenance of localization;0.00460299503989326!GO:0046365;monosaccharide catabolic process;0.00463877641567411!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.00471509908778934!GO:0030134;ER to Golgi transport vesicle;0.00475289433916243!GO:0006769;nicotinamide metabolic process;0.00478147663771831!GO:0008234;cysteine-type peptidase activity;0.00479419815317479!GO:0006289;nucleotide-excision repair;0.00487065055142788!GO:0008312;7S RNA binding;0.0051029533986662!GO:0030433;ER-associated protein catabolic process;0.00529234163817203!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.00529234163817203!GO:0030663;COPI coated vesicle membrane;0.005300294888236!GO:0030126;COPI vesicle coat;0.005300294888236!GO:0003682;chromatin binding;0.005300294888236!GO:0006733;oxidoreduction coenzyme metabolic process;0.00543123473606483!GO:0030125;clathrin vesicle coat;0.00548203315066751!GO:0030665;clathrin coated vesicle membrane;0.00548203315066751!GO:0016481;negative regulation of transcription;0.00560063246295645!GO:0000059;protein import into nucleus, docking;0.00568795168495779!GO:0003746;translation elongation factor activity;0.00576593755156931!GO:0006405;RNA export from nucleus;0.00586509172420748!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00598924739828985!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.00605201178742906!GO:0051098;regulation of binding;0.00605201178742906!GO:0047485;protein N-terminus binding;0.0060998933113666!GO:0009161;ribonucleoside monophosphate metabolic process;0.00614576036580685!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.00614576036580685!GO:0031410;cytoplasmic vesicle;0.00616164563908689!GO:0042168;heme metabolic process;0.00616164563908689!GO:0006268;DNA unwinding during replication;0.00620036958062909!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00620036958062909!GO:0031124;mRNA 3'-end processing;0.00628295450308738!GO:0008408;3'-5' exonuclease activity;0.00654331046937939!GO:0006338;chromatin remodeling;0.00696534365759723!GO:0003711;transcription elongation regulator activity;0.00704181008578855!GO:0046489;phosphoinositide biosynthetic process;0.00708804002869905!GO:0030137;COPI-coated vesicle;0.00715112544292635!GO:0043022;ribosome binding;0.00718378973541346!GO:0044262;cellular carbohydrate metabolic process;0.00718572270621355!GO:0048487;beta-tubulin binding;0.00734333229313446!GO:0033673;negative regulation of kinase activity;0.00750557377456953!GO:0006469;negative regulation of protein kinase activity;0.00750557377456953!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00751303913915787!GO:0019320;hexose catabolic process;0.00751303913915787!GO:0008610;lipid biosynthetic process;0.00760627344803559!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.00781535963010514!GO:0009892;negative regulation of metabolic process;0.00783561638793701!GO:0007050;cell cycle arrest;0.00794663936341368!GO:0032200;telomere organization and biogenesis;0.00794663936341368!GO:0000723;telomere maintenance;0.00794663936341368!GO:0007264;small GTPase mediated signal transduction;0.00800746468539188!GO:0000082;G1/S transition of mitotic cell cycle;0.00803855850699608!GO:0000339;RNA cap binding;0.00844109344040327!GO:0016584;nucleosome positioning;0.00856945865400383!GO:0051348;negative regulation of transferase activity;0.00873456556265355!GO:0000209;protein polyubiquitination;0.00889443846192585!GO:0000178;exosome (RNase complex);0.00895252554097382!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.008989009727604!GO:0051090;regulation of transcription factor activity;0.00915473557347465!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00918903087562467!GO:0046164;alcohol catabolic process;0.00928932076503098!GO:0004003;ATP-dependent DNA helicase activity;0.00942598134065071!GO:0032940;secretion by cell;0.00946055401305594!GO:0006096;glycolysis;0.00958548994176354!GO:0045045;secretory pathway;0.00972529152655469!GO:0006118;electron transport;0.00987188912778193!GO:0043130;ubiquitin binding;0.00993873461450809!GO:0032182;small conjugating protein binding;0.00993873461450809!GO:0001836;release of cytochrome c from mitochondria;0.00996939145940734!GO:0019843;rRNA binding;0.0100457994473597!GO:0018193;peptidyl-amino acid modification;0.0100962813457836!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.0104984548581813!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.0104984548581813!GO:0009126;purine nucleoside monophosphate metabolic process;0.0104984548581813!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.0104984548581813!GO:0006284;base-excision repair;0.0107335847313836!GO:0006144;purine base metabolic process;0.0107335847313836!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0108968861709658!GO:0005096;GTPase activator activity;0.0109200375144028!GO:0050662;coenzyme binding;0.0109458367569229!GO:0042613;MHC class II protein complex;0.0109636981025945!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.011072030121386!GO:0046474;glycerophospholipid biosynthetic process;0.0112129814162423!GO:0030119;AP-type membrane coat adaptor complex;0.0112540623257799!GO:0006779;porphyrin biosynthetic process;0.0113259789750621!GO:0033014;tetrapyrrole biosynthetic process;0.0113259789750621!GO:0030521;androgen receptor signaling pathway;0.0114878124541177!GO:0007265;Ras protein signal transduction;0.0115061462141742!GO:0000175;3'-5'-exoribonuclease activity;0.0116760616868859!GO:0007052;mitotic spindle organization and biogenesis;0.0121548295489114!GO:0000139;Golgi membrane;0.0121561499094276!GO:0030518;steroid hormone receptor signaling pathway;0.0123272789322461!GO:0009451;RNA modification;0.0126726144032971!GO:0000287;magnesium ion binding;0.0126726144032971!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0134212374177337!GO:0005832;chaperonin-containing T-complex;0.0136568762841186!GO:0051881;regulation of mitochondrial membrane potential;0.0136830041977956!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0139073080155194!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0140270841800635!GO:0051101;regulation of DNA binding;0.0141755289776992!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.0142580714019058!GO:0051087;chaperone binding;0.0142875591508879!GO:0002521;leukocyte differentiation;0.0143558646394819!GO:0046467;membrane lipid biosynthetic process;0.0143612033829573!GO:0035258;steroid hormone receptor binding;0.0144891353434269!GO:0006767;water-soluble vitamin metabolic process;0.0145449031959332!GO:0030130;clathrin coat of trans-Golgi network vesicle;0.014785272776183!GO:0012510;trans-Golgi network transport vesicle membrane;0.014785272776183!GO:0042393;histone binding;0.0155114064632952!GO:0006740;NADPH regeneration;0.015678397851927!GO:0006098;pentose-phosphate shunt;0.015678397851927!GO:0022411;cellular component disassembly;0.0159859114122077!GO:0022415;viral reproductive process;0.0160083868717394!GO:0009893;positive regulation of metabolic process;0.0160871515807717!GO:0015631;tubulin binding;0.0160871515807717!GO:0033367;protein localization in mast cell secretory granule;0.0160871515807717!GO:0033365;protein localization in organelle;0.0160871515807717!GO:0033371;T cell secretory granule organization and biogenesis;0.0160871515807717!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.0160871515807717!GO:0033375;protease localization in T cell secretory granule;0.0160871515807717!GO:0042629;mast cell granule;0.0160871515807717!GO:0033377;maintenance of protein localization in T cell secretory granule;0.0160871515807717!GO:0033364;mast cell secretory granule organization and biogenesis;0.0160871515807717!GO:0033380;granzyme B localization in T cell secretory granule;0.0160871515807717!GO:0033379;maintenance of protease localization in T cell secretory granule;0.0160871515807717!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.0160871515807717!GO:0033368;protease localization in mast cell secretory granule;0.0160871515807717!GO:0033366;protein localization in secretory granule;0.0160871515807717!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.0160871515807717!GO:0033374;protein localization in T cell secretory granule;0.0160871515807717!GO:0030695;GTPase regulator activity;0.0176892642116245!GO:0019362;pyridine nucleotide metabolic process;0.017858376131272!GO:0042770;DNA damage response, signal transduction;0.018030058515826!GO:0033157;regulation of intracellular protein transport;0.0182950562606101!GO:0042306;regulation of protein import into nucleus;0.0182950562606101!GO:0005669;transcription factor TFIID complex;0.0183832284103206!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0183889212020966!GO:0006275;regulation of DNA replication;0.018470327840772!GO:0009081;branched chain family amino acid metabolic process;0.0184761606817663!GO:0032259;methylation;0.0187481488809835!GO:0019783;small conjugating protein-specific protease activity;0.0188172684718108!GO:0046902;regulation of mitochondrial membrane permeability;0.0190069524553442!GO:0007004;telomere maintenance via telomerase;0.019139679378354!GO:0008180;signalosome;0.0193721493524835!GO:0045941;positive regulation of transcription;0.0194940419953549!GO:0045321;leukocyte activation;0.0195078843562473!GO:0031123;RNA 3'-end processing;0.0196360904639923!GO:0016790;thiolester hydrolase activity;0.0200956436548057!GO:0031625;ubiquitin protein ligase binding;0.0201276633837488!GO:0004448;isocitrate dehydrogenase activity;0.0201672052735588!GO:0051251;positive regulation of lymphocyte activation;0.0207011834413237!GO:0019318;hexose metabolic process;0.0209089983166477!GO:0030131;clathrin adaptor complex;0.0210289182631562!GO:0000228;nuclear chromosome;0.021302353520232!GO:0004843;ubiquitin-specific protease activity;0.0213274910762434!GO:0005869;dynactin complex;0.0213618518186957!GO:0000781;chromosome, telomeric region;0.0213844927942028!GO:0008022;protein C-terminus binding;0.0213939627899742!GO:0044438;microbody part;0.0215809601617698!GO:0044439;peroxisomal part;0.0215809601617698!GO:0000738;DNA catabolic process, exonucleolytic;0.0216155377694711!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0216155377694711!GO:0010257;NADH dehydrogenase complex assembly;0.0216155377694711!GO:0033108;mitochondrial respiratory chain complex assembly;0.0216155377694711!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0217198349821366!GO:0030027;lamellipodium;0.021740143898305!GO:0006783;heme biosynthetic process;0.0219154818843809!GO:0046979;TAP2 binding;0.0219154818843809!GO:0046977;TAP binding;0.0219154818843809!GO:0046978;TAP1 binding;0.0219154818843809!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0219154818843809!GO:0043596;nuclear replication fork;0.022138588780983!GO:0008629;induction of apoptosis by intracellular signals;0.0221751050686973!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0224109053671377!GO:0006672;ceramide metabolic process;0.0226517068478592!GO:0046519;sphingoid metabolic process;0.0226517068478592!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0226634179103402!GO:0005876;spindle microtubule;0.0231395794185223!GO:0006378;mRNA polyadenylation;0.0231395794185223!GO:0009116;nucleoside metabolic process;0.0231408847537419!GO:0051540;metal cluster binding;0.0232338619652201!GO:0051536;iron-sulfur cluster binding;0.0232338619652201!GO:0006519;amino acid and derivative metabolic process;0.0232338619652201!GO:0000118;histone deacetylase complex;0.0233046770654894!GO:0043621;protein self-association;0.0239918397564163!GO:0008538;proteasome activator activity;0.023997030512903!GO:0030041;actin filament polymerization;0.0241538244838215!GO:0046426;negative regulation of JAK-STAT cascade;0.0242282011658818!GO:0005083;small GTPase regulator activity;0.0245526019397497!GO:0009607;response to biotic stimulus;0.0245526019397497!GO:0016301;kinase activity;0.0245526019397497!GO:0005996;monosaccharide metabolic process;0.0246917987391484!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.0249320603811008!GO:0030140;trans-Golgi network transport vesicle;0.0254625652183415!GO:0006308;DNA catabolic process;0.0255799978834556!GO:0043549;regulation of kinase activity;0.026200885507469!GO:0006984;ER-nuclear signaling pathway;0.0263814673559621!GO:0051338;regulation of transferase activity;0.0265205850396614!GO:0051539;4 iron, 4 sulfur cluster binding;0.0268440915906742!GO:0008097;5S rRNA binding;0.0268986180750887!GO:0004576;oligosaccharyl transferase activity;0.0270593046482451!GO:0032507;maintenance of cellular protein localization;0.0274634055939555!GO:0006376;mRNA splice site selection;0.0274634055939555!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0274634055939555!GO:0050851;antigen receptor-mediated signaling pathway;0.0274820262115335!GO:0019900;kinase binding;0.02753748585297!GO:0031529;ruffle organization and biogenesis;0.0278174727779556!GO:0007010;cytoskeleton organization and biogenesis;0.0282837437103653!GO:0000288;mRNA catabolic process, deadenylation-dependent decay;0.0284568839058565!GO:0032774;RNA biosynthetic process;0.0288735140048284!GO:0019238;cyclohydrolase activity;0.0288775560851638!GO:0008250;oligosaccharyl transferase complex;0.0295945382652755!GO:0050178;phenylpyruvate tautomerase activity;0.0302948479303427!GO:0043284;biopolymer biosynthetic process;0.0304024942849392!GO:0030097;hemopoiesis;0.0304024942849392!GO:0043414;biopolymer methylation;0.0304125159732105!GO:0044275;cellular carbohydrate catabolic process;0.0309605356132151!GO:0006351;transcription, DNA-dependent;0.0310960419764198!GO:0043281;regulation of caspase activity;0.0320861579857321!GO:0004221;ubiquitin thiolesterase activity;0.0321710983810823!GO:0031903;microbody membrane;0.0322174512108974!GO:0005778;peroxisomal membrane;0.0322174512108974!GO:0050871;positive regulation of B cell activation;0.0324645380754262!GO:0006354;RNA elongation;0.0324645380754262!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0325361101944135!GO:0006643;membrane lipid metabolic process;0.0326228728972027!GO:0031325;positive regulation of cellular metabolic process;0.0327193867272507!GO:0000910;cytokinesis;0.0330530680673558!GO:0000152;nuclear ubiquitin ligase complex;0.0336410862147955!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0343070340093414!GO:0045039;protein import into mitochondrial inner membrane;0.0343070340093414!GO:0005777;peroxisome;0.0348440752040881!GO:0042579;microbody;0.0348440752040881!GO:0008624;induction of apoptosis by extracellular signals;0.0348805247548617!GO:0005092;GDP-dissociation inhibitor activity;0.0351656514477254!GO:0045892;negative regulation of transcription, DNA-dependent;0.0357283836619043!GO:0003988;acetyl-CoA C-acyltransferase activity;0.0357293640098363!GO:0015036;disulfide oxidoreductase activity;0.035736537266062!GO:0016407;acetyltransferase activity;0.0358671263182224!GO:0016408;C-acyltransferase activity;0.035928360031793!GO:0009303;rRNA transcription;0.0361077768055803!GO:0030098;lymphocyte differentiation;0.0362948789856511!GO:0045185;maintenance of protein localization;0.0372760318711728!GO:0042990;regulation of transcription factor import into nucleus;0.0375214161633586!GO:0042991;transcription factor import into nucleus;0.0375214161633586!GO:0005853;eukaryotic translation elongation factor 1 complex;0.0375382555454034!GO:0005791;rough endoplasmic reticulum;0.0378987558113069!GO:0004428;inositol or phosphatidylinositol kinase activity;0.0380367561811085!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0380367956716035!GO:0000922;spindle pole;0.0387911136869918!GO:0031371;ubiquitin conjugating enzyme complex;0.0388219523208992!GO:0016791;phosphoric monoester hydrolase activity;0.0388219523208992!GO:0050853;B cell receptor signaling pathway;0.0395300012302952!GO:0002483;antigen processing and presentation of endogenous peptide antigen;0.0395300012302952!GO:0019885;antigen processing and presentation of endogenous peptide antigen via MHC class I;0.0395300012302952!GO:0009083;branched chain family amino acid catabolic process;0.0396333063505366!GO:0030508;thiol-disulfide exchange intermediate activity;0.0398930887732287!GO:0005784;translocon complex;0.0404269084621427!GO:0042532;negative regulation of tyrosine phosphorylation of STAT protein;0.0408632307861581!GO:0042518;negative regulation of tyrosine phosphorylation of Stat3 protein;0.0408632307861581!GO:0050732;negative regulation of peptidyl-tyrosine phosphorylation;0.0408632307861581!GO:0042364;water-soluble vitamin biosynthetic process;0.0410382927144992!GO:0046488;phosphatidylinositol metabolic process;0.041051976663002!GO:0004540;ribonuclease activity;0.0411675216289292!GO:0031098;stress-activated protein kinase signaling pathway;0.0418644156587079!GO:0045859;regulation of protein kinase activity;0.0428055028672882!GO:0016605;PML body;0.0431167928280736!GO:0030262;apoptotic nuclear changes;0.0432374946744984!GO:0016044;membrane organization and biogenesis;0.0436124182785245!GO:0000096;sulfur amino acid metabolic process;0.0440580480095503!GO:0008537;proteasome activator complex;0.0443553075207458!GO:0035267;NuA4 histone acetyltransferase complex;0.0445309926315935!GO:0030374;ligand-dependent nuclear receptor transcription coactivator activity;0.0445955201441922!GO:0004748;ribonucleoside-diphosphate reductase activity;0.0447049816078679!GO:0016728;oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor;0.0447049816078679!GO:0051287;NAD binding;0.0452159278751964!GO:0008320;protein transmembrane transporter activity;0.0456514716261487!GO:0051651;maintenance of cellular localization;0.04684791980234!GO:0003702;RNA polymerase II transcription factor activity;0.0474724433111569!GO:0006739;NADP metabolic process;0.047522563490664!GO:0044454;nuclear chromosome part;0.0478532576037247!GO:0009112;nucleobase metabolic process;0.0478907094747407!GO:0031647;regulation of protein stability;0.0478907094747407!GO:0007034;vacuolar transport;0.047941750877652!GO:0042169;SH2 domain binding;0.0481818024451443!GO:0051091;positive regulation of transcription factor activity;0.0481818024451443!GO:0004659;prenyltransferase activity;0.048284286915436!GO:0043624;cellular protein complex disassembly;0.0483469656807043!GO:0032984;macromolecular complex disassembly;0.0485700801258818!GO:0016788;hydrolase activity, acting on ester bonds;0.0488977507128206!GO:0006596;polyamine biosynthetic process;0.0489069504281792!GO:0007253;cytoplasmic sequestering of NF-kappaB;0.0491709606644549!GO:0006919;caspase activation;0.0495946483594064 | |||
|sample_id=10563 | |||
|sample_note= | |||
|sample_sex=unknown | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=POU2F1..3:1.84405278157;POU5F1:1.81338605971;HOXA9_MEIS1:1.69490393331;IRF1,2:1.66853966197;NFKB1_REL_RELA:1.64568209132;IRF7:1.49174859233;CDX1,2,4:1.396137302;PAX6:1.3674984499;NKX6-1,2:1.31520232922;ELF1,2,4:1.25621888659;PDX1:1.25609591506;LMO2:1.03928661283;SPI1:1.00384743864;DMAP1_NCOR{1,2}_SMARC:0.922599822436;PAX3,7:0.915171404905;NFY{A,B,C}:0.905419924473;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.869675026459;YY1:0.847676410982;MYOD1:0.818401934582;ELK1,4_GABP{A,B1}:0.734564739611;RUNX1..3:0.712873968016;POU1F1:0.693420214504;ZEB1:0.664444872595;NANOG{mouse}:0.631727153408;ESR1:0.603062432118;EVI1:0.578600285251;TOPORS:0.526356250211;AIRE:0.526031346951;CRX:0.519857470512;MYB:0.519390382182;ZBTB16:0.518927933678;NR5A1,2:0.485774006726;TP53:0.464370930394;SPIB:0.453115311295;E2F1..5:0.434737161401;FOXP3:0.421862835845;ETS1,2:0.420112056083;OCT4_SOX2{dimer}:0.418539544006;FOXA2:0.402941073046;TFAP4:0.389963367915;CUX2:0.371522911193;FOXP1:0.370921357311;IKZF2:0.367336979938;FOXN1:0.366378462013;ESRRA:0.351794164851;SNAI1..3:0.345821779849;PBX1:0.340326100733;PITX1..3:0.318631134046;RBPJ:0.312066692329;HIF1A:0.310216966981;TLX2:0.304404857522;GATA6:0.273377375363;PRDM1:0.265847128237;PRRX1,2:0.2286801522;VSX1,2:0.155817371924;HOX{A6,A7,B6,B7}:0.148961500039;ATF5_CREB3:0.121552428111;TGIF1:0.117863924052;FOX{F1,F2,J1}:0.114675507216;PAX8:0.106505455577;NRF1:0.0546340960603;RFX2..5_RFXANK_RFXAP:0.0401879840259;STAT1,3:0.0257078289343;ZNF384:0.0245734625029;ZNF143:0.00643232718189;NR6A1:0.00623990843835;GCM1,2:0.000221505089799;STAT5{A,B}:-0.000527920110485;PAX2:-0.0116144955476;DBP:-0.0220703731726;bHLH_family:-0.0340346400029;NKX2-1,4:-0.0378433791852;SOX5:-0.0419584531216;HNF4A_NR2F1,2:-0.0431598478597;ALX4:-0.0490902009985;SOX{8,9,10}:-0.0872023218044;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.091325953909;NKX3-2:-0.0969667483792;EBF1:-0.096990091787;ONECUT1,2:-0.112070343378;RORA:-0.11273903149;AHR_ARNT_ARNT2:-0.116994453072;HES1:-0.117565678879;CDC5L:-0.123738005123;MEF2{A,B,C,D}:-0.145907386845;GATA4:-0.177762236595;GFI1:-0.219720740356;HMGA1,2:-0.247120786204;GFI1B:-0.253338606795;BPTF:-0.25834237521;SMAD1..7,9:-0.263092516821;HOX{A5,B5}:-0.269695367488;ARID5B:-0.289327965498;NFE2:-0.306649999442;BREu{core}:-0.307309349011;FOXQ1:-0.341418771322;HNF1A:-0.34464292399;NFIX:-0.378893268832;SRF:-0.397836214949;STAT2,4,6:-0.431571386834;FOSL2:-0.435240767507;NKX2-3_NKX2-5:-0.443119677804;NKX2-2,8:-0.463269375597;PAX4:-0.470556604857;ATF4:-0.47531203582;CEBPA,B_DDIT3:-0.501571051517;FOS_FOS{B,L1}_JUN{B,D}:-0.515431998452;SOX17:-0.518585127136;SREBF1,2:-0.519657119611;NANOG:-0.536346952982;HOX{A4,D4}:-0.537497406618;UFEwm:-0.543753201379;MAFB:-0.55669554187;CREB1:-0.574771805684;POU3F1..4:-0.609297712871;LEF1_TCF7_TCF7L1,2:-0.617251811832;BACH2:-0.620774415419;EN1,2:-0.666190504481;HAND1,2:-0.671016873617;ZIC1..3:-0.672196951409;LHX3,4:-0.705310678723;HSF1,2:-0.710991646096;RREB1:-0.724188809771;RXR{A,B,G}:-0.727350784437;IKZF1:-0.73600496878;FOXD3:-0.739364442045;HBP1_HMGB_SSRP1_UBTF:-0.746527408333;ZNF238:-0.75161526636;TBP:-0.763624137414;TAL1_TCF{3,4,12}:-0.767560132539;NKX3-1:-0.775730249656;FOXO1,3,4:-0.79422251626;NFE2L2:-0.796916650937;HLF:-0.802668030025;T:-0.813306019036;NHLH1,2:-0.818573898174;EP300:-0.831580501083;ADNP_IRX_SIX_ZHX:-0.838606630329;KLF4:-0.847578886393;TFDP1:-0.855189552609;GLI1..3:-0.856446478595;ZFP161:-0.859562256359;MYBL2:-0.860526235717;MZF1:-0.861280707988;TEF:-0.862711946842;REST:-0.869600864787;RFX1:-0.890412549523;NR1H4:-0.911886868349;ATF2:-0.914746178673;MYFfamily:-0.922939017824;GTF2A1,2:-0.92758647809;TBX4,5:-0.933082279874;ZNF148:-0.942172500695;NFIL3:-0.954579261299;AR:-0.965244837759;HMX1:-0.985210045944;POU6F1:-1.00788946451;JUN:-1.01242899729;PPARG:-1.02419804293;SPZ1:-1.02622928228;NFATC1..3:-1.02901374912;EGR1..3:-1.06174205093;GZF1:-1.0648973933;PATZ1:-1.06691103826;ATF6:-1.07777321811;MTF1:-1.09493802335;TFCP2:-1.10749698128;ZBTB6:-1.13209998313;SOX2:-1.13227660837;GTF2I:-1.17260248214;TLX1..3_NFIC{dimer}:-1.18296307074;MED-1{core}:-1.19332684771;NFE2L1:-1.20422663855;FOXM1:-1.22009463038;MTE{core}:-1.22528359868;HIC1:-1.29387712163;FOX{D1,D2}:-1.30620070007;NR3C1:-1.30997932904;ZNF423:-1.3104457902;XCPE1{core}:-1.32959422091;RXRA_VDR{dimer}:-1.36548643447;FOX{I1,J2}:-1.3686059889;PAX5:-1.39251584296;TFAP2{A,C}:-1.4076474374;MAZ:-1.4192400812;TEAD1:-1.42017081085;SP1:-1.44802754231;PAX1,9:-1.46267993258;XBP1:-1.46676535656;FOXL1:-1.4793682023;TFAP2B:-1.53228810734;ALX1:-1.9917025735 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10563-108A5;search_select_hide=table117:FF:10563-108A5 | |||
}} | }} |
Latest revision as of 14:29, 3 June 2020
Name: | xeroderma pigentosum b cell line:XPL 17 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11813 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11813
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11813
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0172 |
10 | 10 | 0.0348 |
100 | 100 | 0.547 |
101 | 101 | 0.21 |
102 | 102 | 0.45 |
103 | 103 | 0.276 |
104 | 104 | 0.968 |
105 | 105 | 0.945 |
106 | 106 | 0.152 |
107 | 107 | 0.435 |
108 | 108 | 0.742 |
109 | 109 | 0.0159 |
11 | 11 | 0.0583 |
110 | 110 | 0.121 |
111 | 111 | 0.00596 |
112 | 112 | 0.0722 |
113 | 113 | 0.465 |
114 | 114 | 0.131 |
115 | 115 | 0.431 |
116 | 116 | 0.321 |
117 | 117 | 0.0209 |
118 | 118 | 0.0771 |
119 | 119 | 0.0387 |
12 | 12 | 0.892 |
120 | 120 | 0.446 |
121 | 121 | 0.47 |
122 | 122 | 0.284 |
123 | 123 | 0.00382 |
124 | 124 | 0.226 |
125 | 125 | 0.0268 |
126 | 126 | 0.119 |
127 | 127 | 0.182 |
128 | 128 | 0.437 |
129 | 129 | 0.415 |
13 | 13 | 0.209 |
130 | 130 | 0.913 |
131 | 131 | 0.995 |
132 | 132 | 0.957 |
133 | 133 | 0.627 |
134 | 134 | 0.932 |
135 | 135 | 0.901 |
136 | 136 | 0.553 |
137 | 137 | 0.284 |
138 | 138 | 0.555 |
139 | 139 | 0.0624 |
14 | 14 | 0.587 |
140 | 140 | 0.197 |
141 | 141 | 0.192 |
142 | 142 | 0.845 |
143 | 143 | 0.0502 |
144 | 144 | 0.873 |
145 | 145 | 0.335 |
146 | 146 | 0.586 |
147 | 147 | 0.247 |
148 | 148 | 0.105 |
149 | 149 | 0.743 |
15 | 15 | 0.0858 |
150 | 150 | 0.754 |
151 | 151 | 0.876 |
152 | 152 | 0.986 |
153 | 153 | 0.789 |
154 | 154 | 0.762 |
155 | 155 | 0.105 |
156 | 156 | 0.695 |
157 | 157 | 0.527 |
158 | 158 | 0.395 |
159 | 159 | 0.338 |
16 | 16 | 0.537 |
160 | 160 | 0.117 |
161 | 161 | 0.0175 |
162 | 162 | 0.967 |
163 | 163 | 0.649 |
164 | 164 | 0.16 |
165 | 165 | 0.851 |
166 | 166 | 0.453 |
167 | 167 | 0.305 |
168 | 168 | 0.586 |
169 | 169 | 0.0887 |
17 | 17 | 0.391 |
18 | 18 | 0.338 |
19 | 19 | 0.782 |
2 | 2 | 0.945 |
20 | 20 | 0.554 |
21 | 21 | 0.13 |
22 | 22 | 0.702 |
23 | 23 | 0.927 |
24 | 24 | 0.165 |
25 | 25 | 0.208 |
26 | 26 | 0.0611 |
27 | 27 | 0.443 |
28 | 28 | 0.502 |
29 | 29 | 0.0147 |
3 | 3 | 0.0557 |
30 | 30 | 0.461 |
31 | 31 | 0.67 |
32 | 32 | 0.868 |
33 | 33 | 0.364 |
34 | 34 | 0.837 |
35 | 35 | 0.0915 |
36 | 36 | 0.0164 |
37 | 37 | 0.165 |
38 | 38 | 0.124 |
39 | 39 | 0.727 |
4 | 4 | 0.457 |
40 | 40 | 0.141 |
41 | 41 | 0.635 |
42 | 42 | 0.0638 |
43 | 43 | 0.199 |
44 | 44 | 0.0132 |
45 | 45 | 0.689 |
46 | 46 | 0.116 |
47 | 47 | 0.0232 |
48 | 48 | 0.0701 |
49 | 49 | 0.133 |
5 | 5 | 0.779 |
50 | 50 | 0.833 |
51 | 51 | 0.603 |
52 | 52 | 0.993 |
53 | 53 | 0.341 |
54 | 54 | 0.909 |
55 | 55 | 0.733 |
56 | 56 | 0.6 |
57 | 57 | 0.209 |
58 | 58 | 0.0702 |
59 | 59 | 0.13 |
6 | 6 | 0.748 |
60 | 60 | 0.386 |
61 | 61 | 0.0728 |
62 | 62 | 0.0776 |
63 | 63 | 0.322 |
64 | 64 | 0.146 |
65 | 65 | 0.253 |
66 | 66 | 0.704 |
67 | 67 | 0.353 |
68 | 68 | 0.258 |
69 | 69 | 0.924 |
7 | 7 | 0.195 |
70 | 70 | 0.172 |
71 | 71 | 0.0372 |
72 | 72 | 0.228 |
73 | 73 | 0.429 |
74 | 74 | 0.852 |
75 | 75 | 0.0229 |
76 | 76 | 0.438 |
77 | 77 | 0.576 |
78 | 78 | 0.186 |
79 | 79 | 0.87 |
8 | 8 | 0.139 |
80 | 80 | 0.541 |
81 | 81 | 0.241 |
82 | 82 | 0.352 |
83 | 83 | 0.927 |
84 | 84 | 0.174 |
85 | 85 | 0.664 |
86 | 86 | 0.215 |
87 | 87 | 0.112 |
88 | 88 | 0.625 |
89 | 89 | 0.414 |
9 | 9 | 0.968 |
90 | 90 | 0.0479 |
91 | 91 | 0.784 |
92 | 92 | 0.289 |
93 | 93 | 0.907 |
94 | 94 | 0.177 |
95 | 95 | 0.0364 |
96 | 96 | 0.433 |
97 | 97 | 0.223 |
98 | 98 | 0.168 |
99 | 99 | 0.703 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11813
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
DOID:0050427 xeroderma pigmentosum
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0101522 B-lymphocyte cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0002371 (somatic cell)
0000542 (lymphocyte)
0000219 (motile cell)
0000945 (lymphocyte of B lineage)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0002242 (nucleate cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
630 (genetic disease)
0050177 (monogenic disease)
0050427 (xeroderma pigmentosum)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0101522 (B-lymphocyte cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000051 (common lymphoid progenitor)