FF:10706-109H4: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005502 | ||
|ancestors_in_anatomy_facet=UBERON: | |accession_numbers=CAGE;DRX007986;DRR008858;DRZ000283;DRZ001668;DRZ011633;DRZ013018 | ||
| | |ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0002107,UBERON:0002100,UBERON:0001007,UBERON:0004119,UBERON:0000062,UBERON:0000475,UBERON:0000061,UBERON:0000465,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0009569,UBERON:0002368,UBERON:0005177,UBERON:0002365,UBERON:0005172,UBERON:0006925,UBERON:0002530,UBERON:0010317,UBERON:0005173,UBERON:0002417,UBERON:0000949,UBERON:0002330,UBERON:0000916,UBERON:0002423 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0000066,CL:0002371,CL:0000181,CL:0000417,CL:0000668,CL:0000412,CL:0000255,CL:0000182 | |||
|ancestors_in_disease_facet=DOID:4,DOID:162,DOID:14566,DOID:0050687,DOID:7,DOID:305,DOID:5662 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100297,FF:0101120,FF:0100224,FF:0100578,FF:0103191 | |||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
|expression_enrichment_score=chr3:189349162..189349207,+!p2@TP63!1.76!56.93!TP63;;chrX:2418949..2419024,-!p1@DHRSX,p1@ZBED1!1.53!32.93!ZBED1;;chr6:45296048..45296082,+!p1@RUNX2!1.45!31.21!RUNX2;;chr20:30433396..30433414,-!p1@FOXS1!1.30!18.86!FOXS1;;chrX:66763856..66763896,+!p1@AR!1.23!22.98!AR;;chr20:42543441..42543497,+!p1@TOX2!1.22!69.11!TOX2;;chr1:151804244..151804310,-!p1@RORC!1.21!15.09!RORC;;chr3:21792585..21792625,-!p2@ZNF385D!1.20!16.46!ZNF385D;;chr3:114343768..114343822,-!p1@ZBTB20!1.18!61.22!ZBTB20;;chr3:189348969..189349018,+!p4@TP63!1.16!13.38!TP63;;chr17:70117153..70117174,+!p1@SOX9!1.14!132.05!SOX9;;chr1:119530493..119530572,-!p1@TBX15!1.14!12.86!TBX15;;chr20:42543506..42543549,+!p2@TOX2!1.12!29.67!TOX2;;chr3:141087339..141087387,+!p2@ZBTB38!1.10!117.81!ZBTB38;;chr4:111558135..111558198,-!p2@PITX2!1.10!11.66!PITX2;;chr5:134369905..134369972,-!p1@PITX1!1.08!17.15!PITX1;;chr12:66218598..66218645,+!p2@HMGA2!1.07!50.59!HMGA2;;chr6:126240380..126240430,+!p2@NCOA7!1.05!27.10!NCOA7;;chr2:176969228..176969260,+!p1@HOXD11!1.05!10.12!HOXD11;;chr12:66218836..66218888,+!p1@HMGA2!1.03!91.57!HMGA2;;chr9:14180778..14180808,-!p15@NFIB!1.03!9.77!NFIB;;chr3:193853927..193853944,+!p1@HES1!1.02!313.82!HES1;;chr3:114343826..114343869,-!p4@ZBTB20!1.01!18.86!ZBTB20;;chr12:26277817..26277863,-!p2@BHLHE41!1.01!12.52!BHLHE41;;chr3:21792682..21792720,-!p1@ZNF385D!1.00!8.92!ZNF385D;;chr5:158526917..158526932,-!p1@EBF1!0.97!21.26!EBF1;;chr19:45971246..45971265,+!p1@FOSB!0.96!157.25!FOSB;;chr3:141087393..141087426,+!p3@ZBTB38!0.96!33.27!ZBTB38;;chr20:50179368..50179392,-!p2@NFATC2!0.96!10.63!NFATC2;;chr7:14028488..14028516,-!p2@ETV1!0.96!8.92!ETV1;;chr14:75745523..75745537,+!p1@FOS!0.94!965.48!FOS;;chr1:158969752..158969780,+!p6@IFI16!0.94!13.55!IFI16;;chr6:28321971..28321995,-!p1@ZNF323!0.94!7.72!ZNF323;;chr12:26277956..26277980,-!p1@BHLHE41!0.92!27.61!BHLHE41;;chr17:38256799..38256815,-!p3@NR1D1!0.92!13.72!NR1D1;;chr6:10412600..10412637,-!p1@TFAP2A!0.92!12.52!TFAP2A;;chr3:157823517..157823562,-!p1@SHOX2!0.91!7.72!SHOX2;;chr7:26191809..26191890,+!p1@NFE2L3!0.90!35.67!NFE2L3;;chr7:17338266..17338282,+!p1@AHR!0.89!77.34!AHR;;chr2:178128149..178128198,-!p2@NFE2L2!0.89!38.41!NFE2L2;;chr12:66218255..66218304,+!p3@HMGA2!0.89!19.04!HMGA2;;chr5:124082322..124082364,-!p1@ZNF608!0.89!18.01!ZNF608;;chr3:5021268..5021282,+!p4@BHLHE40!0.89!14.40!BHLHE40;;chr17:38256822..38256851,-!p1@NR1D1!0.88!54.88!NR1D1;;chr8:116681409..116681431,-!p2@TRPS1!0.88!19.04!TRPS1;;chrX:66763815..66763854,+!p2@AR!0.87!8.57!AR;;chr12:125003087..125003141,-!p4@NCOR2!0.87!8.40!NCOR2;;chr10:63809013..63809041,+!p3@ARID5B!0.86!36.36!ARID5B;;chr7:14029283..14029311,-!p1@ETV1!0.86!35.16!ETV1;;chr3:71179699..71179744,-!p2@FOXP1!0.84!47.16!FOXP1;;chr11:46299199..46299233,+!p1@CREB3L1!0.83!31.90!CREB3L1;;chr16:86544113..86544145,+!p1@FOXF1!0.83!7.37!FOXF1;;chr12:77459306..77459365,-!p1@E2F7!0.82!74.94!E2F7;;chr19:13134772..13134822,+!p2@NFIX!0.82!8.40!NFIX;;chr9:16728327..16728338,-!p5@BNC2!0.82!5.66!BNC2;;chr6:35310395..35310410,+!p2@PPARD!0.81!22.64!PPARD;;chr5:124084493..124084524,-!p2@ZNF608!0.80!12.69!ZNF608;;chr9:16728161..16728185,-!p4@BNC2!0.80!5.32!BNC2;;chr15:80843484..80843499,+!p5@ARNT2!0.80!5.32!ARNT2;;chr2:101436564..101436647,+!p1@NPAS2!0.79!114.55!NPAS2;;chr3:5021191..5021202,+!p3@BHLHE40!0.79!14.75!BHLHE40;;chr17:17726907..17726958,-!p2@SREBF1!0.78!34.13!SREBF1;;chr9:16705069..16705086,-!p3@BNC2!0.78!4.97!BNC2;;chr8:11561684..11561751,+!p1@GATA4!0.78!4.97!GATA4;;chr11:66886717..66886762,+!p1@KDM2A!0.76!108.55!KDM2A;;chr14:62162258..62162269,+!p2@HIF1A!0.76!50.59!HIF1A;;chr21:47063625..47063658,+!p1@PCBP3!0.76!22.64!PCBP3;;chr17:41623692..41623715,-!p1@ETV4!0.76!22.12!ETV4;;chr17:53342311..53342400,+!p1@HLF!0.76!5.49!HLF;;chr6:10412392..10412409,-!p4@TFAP2A!0.76!5.49!TFAP2A;;chr3:21792631..21792665,-!p3@ZNF385D!0.76!4.80!ZNF385D;;chr2:46524897..46524911,+!p2@EPAS1!0.75!13.89!EPAS1;;chr2:231090433..231090469,+!p1@SP140!0.75!4.63!SP140;;chr16:67198683..67198698,+!p2@HSF4!0.75!4.63!HSF4;;chr1:158979686..158979745,+!p1@IFI16!0.74!166.69!IFI16;;chr6:168227552..168227609,+!p1@MLLT4!0.74!40.99!MLLT4;;chr6:45390025..45390076,+!p2@RUNX2!0.74!11.66!RUNX2;;chr2:157189180..157189290,-!p1@NR4A2!0.73!25.04!NR4A2;;chr16:79633894..79633954,-!p3@MAF!0.73!8.92!MAF;;chr6:126240442..126240459,+!p4@NCOA7!0.73!5.83!NCOA7;;chr16:79634624..79634642,-!p1@MAF!0.72!18.52!MAF;;chr12:66218212..66218244,+!p5@HMGA2!0.72!6.52!HMGA2;;chr12:26277929..26277955,-!p3@BHLHE41!0.72!6.35!BHLHE41;;chr5:176738887..176738934,-!p1@MXD3!0.71!31.04!MXD3;;chr14:62162285..62162296,+!p3@HIF1A!0.71!24.18!HIF1A;;chr17:56065729..56065781,-!p2@VEZF1!0.71!19.89!VEZF1;;chr3:114866084..114866118,-!p2@ZBTB20!0.71!16.81!ZBTB20;;chr9:14314522..14314556,-!p3@NFIB!0.71!10.46!NFIB;;chr8:116681194..116681214,-!p1@TRPS1!0.70!42.87!TRPS1;;chr1:158979872..158979898,+!p3@IFI16!0.70!13.72!IFI16;;chr6:45389835..45389861,+!p7@RUNX2!0.70!6.86!RUNX2;;chr1:41827095..41827155,+!p1@FOXO6!0.70!5.66!FOXO6;;chr1:8938709..8938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| |||
|ffid_belonging_in_development=CL:0000134,CL:0000223,UBERON:0001041,UBERON:0002532,UBERON:0006595,UBERON:0003104,UBERON:0004161,UBERON:0009497,UBERON:0010316 | |||
|fonse_cell_line=FF:0100224,FF:0101120 | |fonse_cell_line=FF:0100224,FF:0101120 | ||
|fonse_cell_line_closure=FF:0100224,FF:0101120 | |fonse_cell_line_closure=FF:0100224,FF:0101120 | ||
Line 35: | Line 41: | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/pleomorphic%2520hepatocellular%2520carcinoma%2520cell%2520line%253aSNU-387.CNhs11933.10706-109H4.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/pleomorphic%2520hepatocellular%2520carcinoma%2520cell%2520line%253aSNU-387.CNhs11933.10706-109H4.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/pleomorphic%2520hepatocellular%2520carcinoma%2520cell%2520line%253aSNU-387.CNhs11933.10706-109H4.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/pleomorphic%2520hepatocellular%2520carcinoma%2520cell%2520line%253aSNU-387.CNhs11933.10706-109H4.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/pleomorphic%2520hepatocellular%2520carcinoma%2520cell%2520line%253aSNU-387.CNhs11933.10706-109H4.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10706-109H4 | |id=FF:10706-109H4 | ||
|is_a=DOID:5662;;EFO:0002091;;FF: | |is_a=DOID:5662;;EFO:0002091;;FF:0000210;;FF:0103191 | ||
|is_obsolete= | |||
|library_id=CNhs11933 | |||
|library_id_phase_based=2:CNhs11933 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10706 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10706 | |||
|name=pleomorphic hepatocellular carcinoma cell line:SNU-387 | |name=pleomorphic hepatocellular carcinoma cell line:SNU-387 | ||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
Line 42: | Line 60: | ||
|profile_cagescan=,,, | |profile_cagescan=,,, | ||
|profile_hcage=CNhs11933,LSID835,release010,COMPLETED | |profile_hcage=CNhs11933,LSID835,release010,COMPLETED | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq=,,, | |profile_srnaseq=,,, | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,0.348796296324619,0,-0.0701707208170792,-0.282403560576942,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0252547526784578,0,0,0,0,0,-0.0979578962680575,0,0,-0.0642187419690681,0,0,0,0,0,0,0,0,0,0,0.81208515642306,0,0.091762401360886,0,0.226845215581169,0,0,0,0,0,0,0.0398191077221506,0,0,0,0,0,0.00992067517289969,0.12806825766997,-0.0969923612426051,0,0,0.129501588368072,0.0687378478097941,0,0,0,0,0,0,0,0.0687378478097941,0,0.0687378478097941,0,0,0.0687378478097941,0,0,0,0.104030085645903,0.034368923904897,0,0,0,0,0.0125307031814131,0.0588100532081869,0,0,0,-0.0331500766521935,-0.176828478790971,0,0,0,0.18025896238923,0.0300329064322634,-0.104108276895998,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0911749667365315,0.0687378478097941,0,0,0,0.0756088671108831,0,0,0,0,0,0 | |||
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| |||
|rna_box=109 | |rna_box=109 | ||
|rna_catalog_number= | |rna_catalog_number= | ||
Line 57: | Line 78: | ||
|rna_weight_ug=8.85546 | |rna_weight_ug=8.85546 | ||
|sample_age=41 | |sample_age=41 | ||
|sample_category=cell lines | |||
|sample_cell_catalog=CRL-2237 | |sample_cell_catalog=CRL-2237 | ||
|sample_cell_line=SNU-387 | |sample_cell_line=SNU-387 | ||
Line 69: | Line 91: | ||
|sample_ethnicity=K | |sample_ethnicity=K | ||
|sample_experimental_condition= | |sample_experimental_condition= | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.1558894950431e-212!GO:0005737;cytoplasm;3.90639351051147e-171!GO:0043227;membrane-bound organelle;1.19525976680642e-168!GO:0043231;intracellular membrane-bound organelle;1.23228723677887e-168!GO:0043226;organelle;4.0978080315141e-168!GO:0043229;intracellular organelle;2.07603967738048e-167!GO:0044422;organelle part;1.07174395759209e-130!GO:0044446;intracellular organelle part;7.34998044494561e-129!GO:0044444;cytoplasmic part;1.30692380910216e-117!GO:0032991;macromolecular complex;5.51807879499117e-88!GO:0005515;protein binding;6.26204590978125e-79!GO:0044238;primary metabolic process;8.617792934363e-72!GO:0044237;cellular metabolic process;9.41135110090175e-70!GO:0043170;macromolecule metabolic process;5.22029715825054e-69!GO:0005634;nucleus;9.05098359064342e-68!GO:0030529;ribonucleoprotein complex;5.22351278416856e-66!GO:0044428;nuclear part;1.59327756250323e-63!GO:0043233;organelle lumen;1.65756740252e-60!GO:0031974;membrane-enclosed lumen;1.65756740252e-60!GO:0003723;RNA binding;7.96028884596764e-59!GO:0016043;cellular component organization and biogenesis;4.97700832278667e-52!GO:0005739;mitochondrion;1.0259717280385e-47!GO:0043234;protein complex;2.26506029165546e-47!GO:0019538;protein metabolic process;2.65456779471516e-47!GO:0031090;organelle membrane;5.65911673386855e-46!GO:0033036;macromolecule localization;1.09962564359394e-45!GO:0015031;protein transport;1.11346963033731e-44!GO:0045184;establishment of protein localization;3.34232763538346e-42!GO:0008104;protein localization;1.12417027623203e-41!GO:0044260;cellular macromolecule metabolic process;7.89817010845548e-41!GO:0006412;translation;3.40207431991421e-40!GO:0044267;cellular protein metabolic process;4.34787347387699e-40!GO:0046907;intracellular transport;1.46732138364975e-38!GO:0005840;ribosome;6.41334414236111e-38!GO:0031981;nuclear lumen;8.60745239571692e-38!GO:0043283;biopolymer metabolic process;1.11629546136738e-37!GO:0006396;RNA processing;3.65973317100162e-37!GO:0016071;mRNA metabolic process;1.40468542725454e-35!GO:0005829;cytosol;3.89095455173596e-35!GO:0031967;organelle envelope;6.17769339609067e-35!GO:0031975;envelope;1.41739402366306e-34!GO:0003735;structural constituent of ribosome;2.13222086859125e-33!GO:0044429;mitochondrial part;2.62345616114521e-33!GO:0008380;RNA splicing;4.032365089005e-33!GO:0065003;macromolecular complex assembly;1.80482087851312e-31!GO:0006996;organelle organization and biogenesis;1.88824384163629e-31!GO:0006397;mRNA processing;3.08733264040108e-31!GO:0009058;biosynthetic process;3.81023119215419e-31!GO:0009059;macromolecule biosynthetic process;1.78200641939489e-30!GO:0043228;non-membrane-bound organelle;2.41079332341847e-30!GO:0043232;intracellular non-membrane-bound organelle;2.41079332341847e-30!GO:0006886;intracellular protein transport;5.98301363949754e-30!GO:0006259;DNA metabolic process;9.42391182536319e-30!GO:0044249;cellular biosynthetic process;2.74092856566533e-29!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.74945427832963e-29!GO:0010467;gene expression;7.67423421771294e-29!GO:0033279;ribosomal subunit;3.81850628519188e-28!GO:0022607;cellular component assembly;6.70854465649834e-28!GO:0005654;nucleoplasm;5.95064982102964e-26!GO:0051649;establishment of cellular localization;1.5662278469108e-25!GO:0051641;cellular localization;2.11411564052803e-25!GO:0007049;cell cycle;3.76462496389806e-25!GO:0005681;spliceosome;1.01052523568028e-22!GO:0005740;mitochondrial envelope;2.8629941627609e-22!GO:0000166;nucleotide binding;2.93975343016273e-22!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.15165699481175e-21!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.44447132005329e-21!GO:0012505;endomembrane system;2.49679848494266e-21!GO:0044451;nucleoplasm part;3.87501551674284e-21!GO:0019866;organelle inner membrane;4.09724610456288e-21!GO:0031966;mitochondrial membrane;4.10214840410493e-21!GO:0017111;nucleoside-triphosphatase activity;7.34587317730371e-21!GO:0016462;pyrophosphatase activity;1.12339218381494e-20!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;2.38322425414026e-20!GO:0016817;hydrolase activity, acting on acid anhydrides;3.90354289139694e-20!GO:0008134;transcription factor binding;3.94115393683463e-20!GO:0005783;endoplasmic reticulum;8.15040787646705e-20!GO:0005743;mitochondrial inner membrane;6.11549381738973e-19!GO:0006457;protein folding;1.66838199774416e-18!GO:0006119;oxidative phosphorylation;3.45849149526138e-18!GO:0000278;mitotic cell cycle;5.26236969413186e-18!GO:0048770;pigment granule;8.30170413515274e-18!GO:0042470;melanosome;8.30170413515274e-18!GO:0022402;cell cycle process;1.09013196165189e-17!GO:0044445;cytosolic part;2.12448310420883e-17!GO:0022618;protein-RNA complex assembly;4.38493370333045e-17!GO:0006974;response to DNA damage stimulus;6.74228554130274e-17!GO:0006512;ubiquitin cycle;3.01125004341027e-16!GO:0044265;cellular macromolecule catabolic process;3.59164437781705e-16!GO:0003676;nucleic acid binding;5.15817199665842e-16!GO:0044432;endoplasmic reticulum part;9.25103312474963e-16!GO:0051603;proteolysis involved in cellular protein catabolic process;1.10607348635634e-15!GO:0005794;Golgi apparatus;1.28315395848537e-15!GO:0044455;mitochondrial membrane part;1.8903394578311e-15!GO:0019941;modification-dependent protein catabolic process;2.39101528773115e-15!GO:0043632;modification-dependent macromolecule catabolic process;2.39101528773115e-15!GO:0006511;ubiquitin-dependent protein catabolic process;2.39335862113367e-15!GO:0032553;ribonucleotide binding;2.41851785833554e-15!GO:0032555;purine ribonucleotide binding;2.41851785833554e-15!GO:0044257;cellular protein catabolic process;3.0642607935e-15!GO:0016874;ligase activity;4.07009924413149e-15!GO:0017076;purine nucleotide binding;4.22387233068891e-15!GO:0005694;chromosome;5.84141931796789e-15!GO:0043285;biopolymer catabolic process;1.26375006291187e-14!GO:0015934;large ribosomal subunit;1.26375006291187e-14!GO:0015935;small ribosomal subunit;2.16704998560353e-14!GO:0008135;translation factor activity, nucleic acid binding;3.27259823304185e-14!GO:0006605;protein targeting;3.54050555903195e-14!GO:0048193;Golgi vesicle transport;3.83867715994258e-14!GO:0012501;programmed cell death;4.35168448119218e-14!GO:0000087;M phase of mitotic cell cycle;5.05875304642828e-14!GO:0000502;proteasome complex (sensu Eukaryota);8.13073321272306e-14!GO:0006915;apoptosis;8.13073321272306e-14!GO:0007067;mitosis;9.04421823093556e-14!GO:0009057;macromolecule catabolic process;9.63027604311225e-14!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.01180583077314e-13!GO:0016192;vesicle-mediated transport;1.12572667409674e-13!GO:0006281;DNA repair;1.37489639638668e-13!GO:0005635;nuclear envelope;1.54548683324669e-13!GO:0022403;cell cycle phase;1.63219226803028e-13!GO:0044427;chromosomal part;1.99510950210388e-13!GO:0043412;biopolymer modification;2.46175189668212e-13!GO:0051301;cell division;2.59078864034958e-13!GO:0031980;mitochondrial lumen;3.21169434403474e-13!GO:0005759;mitochondrial matrix;3.21169434403474e-13!GO:0051276;chromosome organization and biogenesis;4.18044084315527e-13!GO:0044248;cellular catabolic process;4.19856594107437e-13!GO:0051082;unfolded protein binding;4.88249096490279e-13!GO:0005746;mitochondrial respiratory chain;5.7959351680451e-13!GO:0008219;cell death;6.81458222111741e-13!GO:0016265;death;6.81458222111741e-13!GO:0030163;protein catabolic process;8.38402284857075e-13!GO:0005793;ER-Golgi intermediate compartment;1.18162882651401e-12!GO:0050136;NADH dehydrogenase (quinone) activity;1.18221154599399e-12!GO:0003954;NADH dehydrogenase activity;1.18221154599399e-12!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.18221154599399e-12!GO:0003712;transcription cofactor activity;2.02849868651283e-12!GO:0005524;ATP binding;2.47035434977306e-12!GO:0006913;nucleocytoplasmic transport;3.7092251210571e-12!GO:0009719;response to endogenous stimulus;4.24484937546865e-12!GO:0016070;RNA metabolic process;5.06124878330261e-12!GO:0051186;cofactor metabolic process;5.15660381486552e-12!GO:0032559;adenyl ribonucleotide binding;5.30399556969876e-12!GO:0006464;protein modification process;5.30399556969876e-12!GO:0005730;nucleolus;7.81993032851208e-12!GO:0051169;nuclear transport;1.07691352601521e-11!GO:0030554;adenyl nucleotide binding;1.11004819652007e-11!GO:0000398;nuclear mRNA splicing, via spliceosome;1.14022124186838e-11!GO:0000375;RNA splicing, via transesterification reactions;1.14022124186838e-11!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.14022124186838e-11!GO:0006325;establishment and/or maintenance of chromatin architecture;1.71540273205666e-11!GO:0006260;DNA replication;1.84323339082401e-11!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.90475284595015e-11!GO:0016604;nuclear body;2.58322441238754e-11!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);2.61932454026764e-11!GO:0016887;ATPase activity;2.80233239896822e-11!GO:0006366;transcription from RNA polymerase II promoter;3.33461916895568e-11!GO:0031965;nuclear membrane;3.54909946158062e-11!GO:0006323;DNA packaging;5.81470746368154e-11!GO:0005789;endoplasmic reticulum membrane;6.09877366118519e-11!GO:0042775;organelle ATP synthesis coupled electron transport;9.7274806442326e-11!GO:0042773;ATP synthesis coupled electron transport;9.7274806442326e-11!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.01044670779117e-10!GO:0030964;NADH dehydrogenase complex (quinone);1.14957343320139e-10!GO:0045271;respiratory chain complex I;1.14957343320139e-10!GO:0005747;mitochondrial respiratory chain complex I;1.14957343320139e-10!GO:0006413;translational initiation;1.19391536711752e-10!GO:0044453;nuclear membrane part;1.20727341782286e-10!GO:0003743;translation initiation factor activity;1.26511088092144e-10!GO:0005761;mitochondrial ribosome;1.48285343982622e-10!GO:0000313;organellar ribosome;1.48285343982622e-10!GO:0006461;protein complex assembly;1.57355505936481e-10!GO:0000279;M phase;2.56771828892123e-10!GO:0043687;post-translational protein modification;2.69679594252575e-10!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;2.73114712944165e-10!GO:0015630;microtubule cytoskeleton;3.72107631287861e-10!GO:0042623;ATPase activity, coupled;3.77804357285747e-10!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;3.96154743890995e-10!GO:0005768;endosome;7.57125752803106e-10!GO:0016607;nuclear speck;9.49767280864174e-10!GO:0006446;regulation of translational initiation;1.35438876883433e-09!GO:0006732;coenzyme metabolic process;1.7900803611204e-09!GO:0051726;regulation of cell cycle;2.72129435081215e-09!GO:0000074;regulation of progression through cell cycle;2.7434542500763e-09!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;3.676025596867e-09!GO:0004386;helicase activity;4.7115761419556e-09!GO:0017038;protein import;4.87302290736985e-09!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;7.89165409981872e-09!GO:0048523;negative regulation of cellular process;8.31350598419325e-09!GO:0000785;chromatin;1.04976748505443e-08!GO:0008639;small protein conjugating enzyme activity;1.05245336041514e-08!GO:0051246;regulation of protein metabolic process;1.36229930007049e-08!GO:0008565;protein transporter activity;1.99570838445527e-08!GO:0004842;ubiquitin-protein ligase activity;2.32100654381119e-08!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;2.42170432516917e-08!GO:0050794;regulation of cellular process;2.59246938548157e-08!GO:0007249;I-kappaB kinase/NF-kappaB cascade;2.9311442281794e-08!GO:0016879;ligase activity, forming carbon-nitrogen bonds;2.97065035139481e-08!GO:0003924;GTPase activity;3.2097789599356e-08!GO:0006888;ER to Golgi vesicle-mediated transport;3.98449965206668e-08!GO:0043067;regulation of programmed cell death;4.17262526937466e-08!GO:0042981;regulation of apoptosis;4.36932872821154e-08!GO:0006403;RNA localization;5.14934920511778e-08!GO:0019787;small conjugating protein ligase activity;5.19839462632686e-08!GO:0009055;electron carrier activity;6.52763687208445e-08!GO:0005643;nuclear pore;6.87133462138899e-08!GO:0050657;nucleic acid transport;6.87133462138899e-08!GO:0051236;establishment of RNA localization;6.87133462138899e-08!GO:0050658;RNA transport;6.87133462138899e-08!GO:0006163;purine nucleotide metabolic process;1.15343753428201e-07!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.17686677503644e-07!GO:0016568;chromatin modification;1.31188288894955e-07!GO:0048475;coated membrane;1.41284886723252e-07!GO:0030117;membrane coat;1.41284886723252e-07!GO:0043566;structure-specific DNA binding;1.42932311761556e-07!GO:0065004;protein-DNA complex assembly;1.4419110282178e-07!GO:0006333;chromatin assembly or disassembly;1.45991092584685e-07!GO:0009259;ribonucleotide metabolic process;1.62995483374074e-07!GO:0009056;catabolic process;1.87916189352949e-07!GO:0016881;acid-amino acid ligase activity;2.03648619493615e-07!GO:0030120;vesicle coat;2.28487335919249e-07!GO:0030662;coated vesicle membrane;2.28487335919249e-07!GO:0009150;purine ribonucleotide metabolic process;2.32263103208393e-07!GO:0006164;purine nucleotide biosynthetic process;2.41798725843258e-07!GO:0007243;protein kinase cascade;2.57723233086196e-07!GO:0005813;centrosome;3.02360273761675e-07!GO:0048519;negative regulation of biological process;3.98495231488944e-07!GO:0005819;spindle;4.12545352818239e-07!GO:0051170;nuclear import;4.29996671265164e-07!GO:0009152;purine ribonucleotide biosynthetic process;4.83870372593928e-07!GO:0009142;nucleoside triphosphate biosynthetic process;5.20327664854962e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;5.20327664854962e-07!GO:0009060;aerobic respiration;5.20327664854962e-07!GO:0005773;vacuole;5.54358631232302e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;5.85588297186188e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;5.85588297186188e-07!GO:0015986;ATP synthesis coupled proton transport;6.02261410157601e-07!GO:0015985;energy coupled proton transport, down electrochemical gradient;6.02261410157601e-07!GO:0009199;ribonucleoside triphosphate metabolic process;6.07165188857782e-07!GO:0005667;transcription factor complex;6.13546783936484e-07!GO:0005788;endoplasmic reticulum lumen;6.38810448588026e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;6.95982223793667e-07!GO:0009144;purine nucleoside triphosphate metabolic process;6.95982223793667e-07!GO:0009260;ribonucleotide biosynthetic process;7.83357459255962e-07!GO:0044431;Golgi apparatus part;7.83357459255962e-07!GO:0005815;microtubule organizing center;8.07863434608734e-07!GO:0045333;cellular respiration;8.33301071221389e-07!GO:0006606;protein import into nucleus;8.33301071221389e-07!GO:0043069;negative regulation of programmed cell death;8.34250839729325e-07!GO:0032446;protein modification by small protein conjugation;8.81108985579784e-07!GO:0009141;nucleoside triphosphate metabolic process;8.84886602271994e-07!GO:0005770;late endosome;9.32007593734541e-07!GO:0008026;ATP-dependent helicase activity;1.062638158015e-06!GO:0065002;intracellular protein transport across a membrane;1.09077047027675e-06!GO:0003697;single-stranded DNA binding;1.22904636304676e-06!GO:0031324;negative regulation of cellular metabolic process;1.36798541863052e-06!GO:0019829;cation-transporting ATPase activity;1.45892688418638e-06!GO:0016787;hydrolase activity;1.49099157598951e-06!GO:0005798;Golgi-associated vesicle;1.61622152054473e-06!GO:0003713;transcription coactivator activity;1.66232624564518e-06!GO:0043066;negative regulation of apoptosis;1.80318983746798e-06!GO:0005839;proteasome core complex (sensu Eukaryota);1.93228786703577e-06!GO:0016567;protein ubiquitination;2.21181412543906e-06!GO:0007005;mitochondrion organization and biogenesis;2.22327875184811e-06!GO:0051028;mRNA transport;2.66875174296468e-06!GO:0000245;spliceosome assembly;2.71615424999449e-06!GO:0046930;pore complex;2.78592521384173e-06!GO:0016563;transcription activator activity;2.94613802855033e-06!GO:0044440;endosomal part;3.10676956690224e-06!GO:0010008;endosome membrane;3.10676956690224e-06!GO:0042254;ribosome biogenesis and assembly;3.13791851451315e-06!GO:0006793;phosphorus metabolic process;3.18436240853662e-06!GO:0006796;phosphate metabolic process;3.18436240853662e-06!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;3.67358873955376e-06!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;4.26876906631452e-06!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;4.43205966345675e-06!GO:0000775;chromosome, pericentric region;4.44998728211692e-06!GO:0006754;ATP biosynthetic process;4.60331179034432e-06!GO:0006753;nucleoside phosphate metabolic process;4.60331179034432e-06!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;5.11455333409558e-06!GO:0004812;aminoacyl-tRNA ligase activity;5.11455333409558e-06!GO:0016875;ligase activity, forming carbon-oxygen bonds;5.11455333409558e-06!GO:0000323;lytic vacuole;5.32089211145101e-06!GO:0005764;lysosome;5.32089211145101e-06!GO:0046034;ATP metabolic process;6.40864701620995e-06!GO:0000151;ubiquitin ligase complex;6.46647220991104e-06!GO:0016564;transcription repressor activity;7.00881297005051e-06!GO:0003714;transcription corepressor activity;7.28727616598735e-06!GO:0043038;amino acid activation;7.6531502154111e-06!GO:0006418;tRNA aminoacylation for protein translation;7.6531502154111e-06!GO:0043039;tRNA aminoacylation;7.6531502154111e-06!GO:0007010;cytoskeleton organization and biogenesis;8.09440193007219e-06!GO:0031988;membrane-bound vesicle;8.09440193007219e-06!GO:0009892;negative regulation of metabolic process;8.26793725470156e-06!GO:0006950;response to stress;8.70659362025832e-06!GO:0043623;cellular protein complex assembly;8.70659362025832e-06!GO:0051188;cofactor biosynthetic process;8.97069762933382e-06!GO:0006099;tricarboxylic acid cycle;9.59827163082969e-06!GO:0046356;acetyl-CoA catabolic process;9.59827163082969e-06!GO:0048522;positive regulation of cellular process;9.97469535649374e-06!GO:0005525;GTP binding;1.00135619756238e-05!GO:0030133;transport vesicle;1.0119252267515e-05!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.05257652930104e-05!GO:0050789;regulation of biological process;1.06937538098764e-05!GO:0015078;hydrogen ion transmembrane transporter activity;1.08614018175888e-05!GO:0004298;threonine endopeptidase activity;1.13984132757288e-05!GO:0006357;regulation of transcription from RNA polymerase II promoter;1.3670641603179e-05!GO:0006399;tRNA metabolic process;1.39069691646295e-05!GO:0006613;cotranslational protein targeting to membrane;1.44522843112711e-05!GO:0016023;cytoplasmic membrane-bound vesicle;1.52273905829118e-05!GO:0007051;spindle organization and biogenesis;1.54217576320162e-05!GO:0051187;cofactor catabolic process;2.07574998714667e-05!GO:0045259;proton-transporting ATP synthase complex;2.19419540367788e-05!GO:0016310;phosphorylation;2.46823816501242e-05!GO:0030532;small nuclear ribonucleoprotein complex;2.81988466657645e-05!GO:0006334;nucleosome assembly;2.88683105612242e-05!GO:0051325;interphase;2.90714346118346e-05!GO:0016469;proton-transporting two-sector ATPase complex;2.92617291813114e-05!GO:0006084;acetyl-CoA metabolic process;2.93721273970491e-05!GO:0051329;interphase of mitotic cell cycle;2.9991258438773e-05!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.11424963724596e-05!GO:0030867;rough endoplasmic reticulum membrane;3.15437243043672e-05!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;3.47196067813898e-05!GO:0030036;actin cytoskeleton organization and biogenesis;3.56779265893315e-05!GO:0006916;anti-apoptosis;3.68515260707135e-05!GO:0031982;vesicle;3.99861725144952e-05!GO:0000139;Golgi membrane;4.17231438909134e-05!GO:0006261;DNA-dependent DNA replication;4.42517349380158e-05!GO:0051789;response to protein stimulus;4.47367392792801e-05!GO:0006986;response to unfolded protein;4.47367392792801e-05!GO:0051427;hormone receptor binding;4.52309295317269e-05!GO:0005769;early endosome;4.86988754648569e-05!GO:0009109;coenzyme catabolic process;4.89961473013234e-05!GO:0016491;oxidoreductase activity;5.17044489473754e-05!GO:0009117;nucleotide metabolic process;5.57868003546805e-05!GO:0019899;enzyme binding;5.70085198862937e-05!GO:0009967;positive regulation of signal transduction;6.3895144942181e-05!GO:0016859;cis-trans isomerase activity;6.56770767393271e-05!GO:0035257;nuclear hormone receptor binding;7.66324721506902e-05!GO:0016779;nucleotidyltransferase activity;8.19797565146333e-05!GO:0006612;protein targeting to membrane;8.65541971663991e-05!GO:0031252;leading edge;9.50310531670598e-05!GO:0031410;cytoplasmic vesicle;9.50310531670598e-05!GO:0065009;regulation of a molecular function;0.000101825873349537!GO:0031497;chromatin assembly;0.000105097779078657!GO:0016481;negative regulation of transcription;0.000107831120500209!GO:0007264;small GTPase mediated signal transduction;0.000109710581934283!GO:0009108;coenzyme biosynthetic process;0.000110780764205343!GO:0008361;regulation of cell size;0.000127719584932689!GO:0008654;phospholipid biosynthetic process;0.000128436696471836!GO:0016740;transferase activity;0.000132364967913938!GO:0051168;nuclear export;0.000144021763467054!GO:0016772;transferase activity, transferring phosphorus-containing groups;0.000149037411976951!GO:0003729;mRNA binding;0.000149445883490686!GO:0019867;outer membrane;0.000152949540207801!GO:0031968;organelle outer membrane;0.000154207855533312!GO:0003690;double-stranded DNA binding;0.000154507724897658!GO:0048471;perinuclear region of cytoplasm;0.000178471040932603!GO:0032561;guanyl ribonucleotide binding;0.000189292797310821!GO:0019001;guanyl nucleotide binding;0.000189292797310821!GO:0042802;identical protein binding;0.000192130524869429!GO:0016049;cell growth;0.000197836149690304!GO:0046983;protein dimerization activity;0.000237846777645849!GO:0045786;negative regulation of progression through cell cycle;0.000257914747983804!GO:0003724;RNA helicase activity;0.000260392473975607!GO:0033116;ER-Golgi intermediate compartment membrane;0.000272584239748369!GO:0016853;isomerase activity;0.000285111239182237!GO:0015077;monovalent inorganic cation transmembrane transporter activity;0.000393294683154143!GO:0045454;cell redox homeostasis;0.000418641376431847!GO:0006752;group transfer coenzyme metabolic process;0.000437887158978457!GO:0015980;energy derivation by oxidation of organic compounds;0.000444870340495416!GO:0005657;replication fork;0.000480991094053114!GO:0008094;DNA-dependent ATPase activity;0.000490171045786912!GO:0030029;actin filament-based process;0.000530206553744825!GO:0005885;Arp2/3 protein complex;0.000532351734907605!GO:0005741;mitochondrial outer membrane;0.000555824295636561!GO:0005874;microtubule;0.000560702299970578!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000694412126769808!GO:0006364;rRNA processing;0.000694412126769808!GO:0043021;ribonucleoprotein binding;0.000695500122980218!GO:0005048;signal sequence binding;0.000752964550297867!GO:0000776;kinetochore;0.000777097137435683!GO:0007052;mitotic spindle organization and biogenesis;0.000805584381678847!GO:0005762;mitochondrial large ribosomal subunit;0.000806050944511826!GO:0000315;organellar large ribosomal subunit;0.000806050944511826!GO:0051052;regulation of DNA metabolic process;0.000813127494993229!GO:0001558;regulation of cell growth;0.000828273308023543!GO:0065007;biological regulation;0.000871710089529267!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000911305957349709!GO:0005905;coated pit;0.000913302727955169!GO:0048518;positive regulation of biological process;0.000920083680658855!GO:0008047;enzyme activator activity;0.000950164455462855!GO:0045893;positive regulation of transcription, DNA-dependent;0.000976198197724329!GO:0000075;cell cycle checkpoint;0.00101768646392054!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.00106630234905766!GO:0016072;rRNA metabolic process;0.00111644568914109!GO:0006302;double-strand break repair;0.00119044871928965!GO:0005791;rough endoplasmic reticulum;0.00119044871928965!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.00132978626368535!GO:0015399;primary active transmembrane transporter activity;0.00132978626368535!GO:0009966;regulation of signal transduction;0.00134842492141749!GO:0051920;peroxiredoxin activity;0.00135426366339722!GO:0030658;transport vesicle membrane;0.00142147887796384!GO:0006091;generation of precursor metabolites and energy;0.00142433146417775!GO:0045941;positive regulation of transcription;0.00145273405383427!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00151121298582398!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00153264716050225!GO:0007242;intracellular signaling cascade;0.00158655941971526!GO:0016197;endosome transport;0.00160581613249162!GO:0007088;regulation of mitosis;0.0016226746628362!GO:0003899;DNA-directed RNA polymerase activity;0.00165481306391799!GO:0006891;intra-Golgi vesicle-mediated transport;0.00165481306391799!GO:0005096;GTPase activator activity;0.00167201652883725!GO:0004674;protein serine/threonine kinase activity;0.00184596441028248!GO:0030134;ER to Golgi transport vesicle;0.00200472645647313!GO:0033673;negative regulation of kinase activity;0.00203600305991251!GO:0006469;negative regulation of protein kinase activity;0.00203600305991251!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00207999638745708!GO:0030118;clathrin coat;0.00216661324888139!GO:0044262;cellular carbohydrate metabolic process;0.00217269551764403!GO:0019222;regulation of metabolic process;0.0022017638730698!GO:0051252;regulation of RNA metabolic process;0.00225940751044991!GO:0000314;organellar small ribosomal subunit;0.00227352909962486!GO:0005763;mitochondrial small ribosomal subunit;0.00227352909962486!GO:0003682;chromatin binding;0.00228927407460748!GO:0046489;phosphoinositide biosynthetic process;0.00242594248346894!GO:0016363;nuclear matrix;0.00249010206620924!GO:0031902;late endosome membrane;0.00250547021658757!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00253665576397401!GO:0008092;cytoskeletal protein binding;0.0026451561439289!GO:0008022;protein C-terminus binding;0.0026451561439289!GO:0030663;COPI coated vesicle membrane;0.00273325842985523!GO:0030126;COPI vesicle coat;0.00273325842985523!GO:0007059;chromosome segregation;0.00299173445265997!GO:0005637;nuclear inner membrane;0.0029931687884314!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00299706321408173!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00301664872083261!GO:0016044;membrane organization and biogenesis;0.00302924028288116!GO:0031072;heat shock protein binding;0.00302924028288116!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0030482547310862!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00305548548612227!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00305548548612227!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00305548548612227!GO:0050790;regulation of catalytic activity;0.00306201900170112!GO:0008632;apoptotic program;0.00306674508741534!GO:0008250;oligosaccharyl transferase complex;0.00307734990983478!GO:0051348;negative regulation of transferase activity;0.00329222819088803!GO:0051128;regulation of cellular component organization and biogenesis;0.00344174432798184!GO:0006352;transcription initiation;0.00346957186898609!GO:0046474;glycerophospholipid biosynthetic process;0.00346957186898609!GO:0048487;beta-tubulin binding;0.00367148251148199!GO:0016251;general RNA polymerase II transcription factor activity;0.00400039851352711!GO:0003678;DNA helicase activity;0.00400520971927908!GO:0009165;nucleotide biosynthetic process;0.00400718026691336!GO:0006402;mRNA catabolic process;0.00405365399814265!GO:0043681;protein import into mitochondrion;0.00414040960168138!GO:0048500;signal recognition particle;0.00421276827458541!GO:0008186;RNA-dependent ATPase activity;0.00422229504848631!GO:0030660;Golgi-associated vesicle membrane;0.00424863707295467!GO:0000922;spindle pole;0.00433525192650342!GO:0030132;clathrin coat of coated pit;0.00455137591413076!GO:0019843;rRNA binding;0.00466002686375261!GO:0004576;oligosaccharyl transferase activity;0.00472712901784288!GO:0035258;steroid hormone receptor binding;0.00474069601219166!GO:0003702;RNA polymerase II transcription factor activity;0.00481793642780384!GO:0015631;tubulin binding;0.00483814366679713!GO:0043284;biopolymer biosynthetic process;0.00492902433631715!GO:0030127;COPII vesicle coat;0.0051032773025426!GO:0012507;ER to Golgi transport vesicle membrane;0.0051032773025426!GO:0005876;spindle microtubule;0.00516611734681258!GO:0043492;ATPase activity, coupled to movement of substances;0.00528679340657414!GO:0006607;NLS-bearing substrate import into nucleus;0.00528859312627879!GO:0022890;inorganic cation transmembrane transporter activity;0.00536296871274328!GO:0000082;G1/S transition of mitotic cell cycle;0.00555855505452093!GO:0006417;regulation of translation;0.00568098163451574!GO:0000786;nucleosome;0.00574909716583856!GO:0030119;AP-type membrane coat adaptor complex;0.00575307057838779!GO:0007265;Ras protein signal transduction;0.00580034375085364!GO:0051101;regulation of DNA binding;0.00580034375085364!GO:0007017;microtubule-based process;0.0059949302907451!GO:0016281;eukaryotic translation initiation factor 4F complex;0.0064393875241392!GO:0006414;translational elongation;0.00652251179164251!GO:0030137;COPI-coated vesicle;0.00661421719675677!GO:0006611;protein export from nucleus;0.0067308387112952!GO:0045892;negative regulation of transcription, DNA-dependent;0.00691822501443933!GO:0006892;post-Golgi vesicle-mediated transport;0.00711075300199986!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00731298663308115!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00747496017046938!GO:0005581;collagen;0.00780722462597645!GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;0.00790299485530148!GO:0030027;lamellipodium;0.00827607114235998!GO:0008139;nuclear localization sequence binding;0.00827607114235998!GO:0006740;NADPH regeneration;0.00827607114235998!GO:0006098;pentose-phosphate shunt;0.00827607114235998!GO:0032507;maintenance of cellular protein localization;0.00827667441073644!GO:0003746;translation elongation factor activity;0.00830502754969931!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00855129703112042!GO:0016584;nucleosome positioning;0.00868160291199496!GO:0005774;vacuolar membrane;0.00870250857539145!GO:0017166;vinculin binding;0.00876855747329002!GO:0030131;clathrin adaptor complex;0.00883179020140252!GO:0031625;ubiquitin protein ligase binding;0.00894974270793715!GO:0048468;cell development;0.00894974270793715!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00895653795789155!GO:0045047;protein targeting to ER;0.00895653795789155!GO:0043065;positive regulation of apoptosis;0.00905579473864775!GO:0006767;water-soluble vitamin metabolic process;0.00912275441140956!GO:0007040;lysosome organization and biogenesis;0.00947336081413521!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0096427780543096!GO:0005099;Ras GTPase activator activity;0.00996521730201451!GO:0046467;membrane lipid biosynthetic process;0.00998591111935968!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.0100840405365472!GO:0030521;androgen receptor signaling pathway;0.0101375382279819!GO:0007093;mitotic cell cycle checkpoint;0.0104168713563245!GO:0005083;small GTPase regulator activity;0.0106835180004373!GO:0004004;ATP-dependent RNA helicase activity;0.0106970186617276!GO:0016628;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;0.010907483663283!GO:0006310;DNA recombination;0.01095326103182!GO:0051087;chaperone binding;0.0116636820354879!GO:0043068;positive regulation of programmed cell death;0.0116731728422474!GO:0006497;protein amino acid lipidation;0.0117742949816152!GO:0007030;Golgi organization and biogenesis;0.0118232038105816!GO:0043407;negative regulation of MAP kinase activity;0.0119206440386987!GO:0042158;lipoprotein biosynthetic process;0.0119644579148014!GO:0008234;cysteine-type peptidase activity;0.0119936794508944!GO:0005684;U2-dependent spliceosome;0.0121635935002965!GO:0007033;vacuole organization and biogenesis;0.0122764161995038!GO:0051098;regulation of binding;0.0123380232621767!GO:0006383;transcription from RNA polymerase III promoter;0.0127826683458219!GO:0030880;RNA polymerase complex;0.0127935758462077!GO:0046822;regulation of nucleocytoplasmic transport;0.0128225120580478!GO:0043488;regulation of mRNA stability;0.0128477967447884!GO:0043487;regulation of RNA stability;0.0128477967447884!GO:0016126;sterol biosynthetic process;0.0129298755496494!GO:0031326;regulation of cellular biosynthetic process;0.0131470329622662!GO:0007034;vacuolar transport;0.0133240905802557!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0139538509717145!GO:0006839;mitochondrial transport;0.0146768350067546!GO:0045045;secretory pathway;0.0147119664868066!GO:0006405;RNA export from nucleus;0.0147268030382861!GO:0003684;damaged DNA binding;0.0147408019186624!GO:0031418;L-ascorbic acid binding;0.0148231862949327!GO:0018196;peptidyl-asparagine modification;0.0148842796433968!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0148842796433968!GO:0030659;cytoplasmic vesicle membrane;0.0152651588634996!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0158442969063111!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0158442969063111!GO:0045792;negative regulation of cell size;0.0158704429306615!GO:0008312;7S RNA binding;0.0167956679631867!GO:0005869;dynactin complex;0.016835563772163!GO:0030176;integral to endoplasmic reticulum membrane;0.0170866742526794!GO:0031901;early endosome membrane;0.0175228378121721!GO:0051651;maintenance of cellular localization;0.0175956365850596!GO:0050662;coenzyme binding;0.0180995929894232!GO:0006275;regulation of DNA replication;0.0181547722046641!GO:0051539;4 iron, 4 sulfur cluster binding;0.0182433794010498!GO:0005583;fibrillar collagen;0.0183185313991227!GO:0051338;regulation of transferase activity;0.0184346312963958!GO:0030308;negative regulation of cell growth;0.0189515457256435!GO:0008637;apoptotic mitochondrial changes;0.0192657154462287!GO:0043022;ribosome binding;0.0193073509606569!GO:0005875;microtubule associated complex;0.0193073509606569!GO:0005765;lysosomal membrane;0.0195453883033595!GO:0043549;regulation of kinase activity;0.0196977175001984!GO:0044437;vacuolar part;0.0197898855023261!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.0199012340691251!GO:0032508;DNA duplex unwinding;0.0199863226571281!GO:0032392;DNA geometric change;0.0199863226571281!GO:0006401;RNA catabolic process;0.020126737882412!GO:0006595;polyamine metabolic process;0.0203455717839737!GO:0007041;lysosomal transport;0.0205121403162901!GO:0009889;regulation of biosynthetic process;0.0205806297762291!GO:0043087;regulation of GTPase activity;0.0209291456003541!GO:0006695;cholesterol biosynthetic process;0.0215538770313348!GO:0006739;NADP metabolic process;0.021579535559616!GO:0051287;NAD binding;0.0218729221790999!GO:0008610;lipid biosynthetic process;0.0219256801553693!GO:0000059;protein import into nucleus, docking;0.0219633104472332!GO:0051235;maintenance of localization;0.0220749762890106!GO:0016272;prefoldin complex;0.0225491884009639!GO:0030125;clathrin vesicle coat;0.0225600095157751!GO:0030665;clathrin coated vesicle membrane;0.0225600095157751!GO:0030518;steroid hormone receptor signaling pathway;0.0225926319256732!GO:0006506;GPI anchor biosynthetic process;0.0226281030361012!GO:0004177;aminopeptidase activity;0.0229810223030853!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0235008732596504!GO:0030140;trans-Golgi network transport vesicle;0.0235161801916235!GO:0006769;nicotinamide metabolic process;0.0239848535655264!GO:0006376;mRNA splice site selection;0.0239848535655264!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0239848535655264!GO:0004228;gelatinase A activity;0.024266888788677!GO:0001955;blood vessel maturation;0.024266888788677!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.024266888788677!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.0242745796823812!GO:0000428;DNA-directed RNA polymerase complex;0.0242745796823812!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0242745796823812!GO:0008168;methyltransferase activity;0.0243890895102951!GO:0006979;response to oxidative stress;0.024629004167245!GO:0006505;GPI anchor metabolic process;0.0248655833361874!GO:0003756;protein disulfide isomerase activity;0.0250173283492346!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0250173283492346!GO:0046483;heterocycle metabolic process;0.0251068754857149!GO:0003711;transcription elongation regulator activity;0.0257503555747812!GO:0040008;regulation of growth;0.0264911538258818!GO:0030384;phosphoinositide metabolic process;0.0269503473410049!GO:0046966;thyroid hormone receptor binding;0.0269822817423908!GO:0006338;chromatin remodeling;0.0271597714668429!GO:0050811;GABA receptor binding;0.027289456956402!GO:0012506;vesicle membrane;0.0276395183684006!GO:0016741;transferase activity, transferring one-carbon groups;0.0276395183684006!GO:0005832;chaperonin-containing T-complex;0.0278717649429383!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0278717649429383!GO:0006818;hydrogen transport;0.0280493749979953!GO:0006007;glucose catabolic process;0.0281468124605414!GO:0007021;tubulin folding;0.028214695151193!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0283354175159063!GO:0022415;viral reproductive process;0.0291024269975142!GO:0042770;DNA damage response, signal transduction;0.0307173149185631!GO:0008629;induction of apoptosis by intracellular signals;0.0307868005465308!GO:0042585;germinal vesicle;0.031658015706665!GO:0044433;cytoplasmic vesicle part;0.0316931478775834!GO:0042393;histone binding;0.0316931478775834!GO:0006672;ceramide metabolic process;0.0320009946980438!GO:0008017;microtubule binding;0.0321648300959539!GO:0005784;translocon complex;0.032227151505846!GO:0033559;unsaturated fatty acid metabolic process;0.0323924052042142!GO:0006636;unsaturated fatty acid biosynthetic process;0.0323924052042142!GO:0006268;DNA unwinding during replication;0.0324449253609532!GO:0008147;structural constituent of bone;0.0324449253609532!GO:0009893;positive regulation of metabolic process;0.0333115648984865!GO:0016791;phosphoric monoester hydrolase activity;0.0336381051312827!GO:0032940;secretion by cell;0.0342684998131558!GO:0000910;cytokinesis;0.0345995635304022!GO:0000339;RNA cap binding;0.0353882924378254!GO:0007050;cell cycle arrest;0.0355165193470717!GO:0030695;GTPase regulator activity;0.0355283257044268!GO:0051493;regulation of cytoskeleton organization and biogenesis;0.0358812008852819!GO:0033043;regulation of organelle organization and biogenesis;0.0358812008852819!GO:0031543;peptidyl-proline dioxygenase activity;0.0360838988494269!GO:0015992;proton transport;0.0364846791056205!GO:0043624;cellular protein complex disassembly;0.037003030056936!GO:0031124;mRNA 3'-end processing;0.037003030056936!GO:0045185;maintenance of protein localization;0.037003030056936!GO:0000118;histone deacetylase complex;0.0382046875641504!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.0383211652037559!GO:0031577;spindle checkpoint;0.0383211652037559!GO:0045859;regulation of protein kinase activity;0.0383435319504199!GO:0032906;transforming growth factor-beta2 production;0.0388942951620423!GO:0032909;regulation of transforming growth factor-beta2 production;0.0388942951620423!GO:0045926;negative regulation of growth;0.0388942951620423!GO:0006354;RNA elongation;0.0388942951620423!GO:0003923;GPI-anchor transamidase activity;0.0388942951620423!GO:0016255;attachment of GPI anchor to protein;0.0388942951620423!GO:0042765;GPI-anchor transamidase complex;0.0388942951620423!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0394374154326229!GO:0015002;heme-copper terminal oxidase activity;0.0394374154326229!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0394374154326229!GO:0004129;cytochrome-c oxidase activity;0.0394374154326229!GO:0035035;histone acetyltransferase binding;0.0394723649344768!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0397015316673812!GO:0004003;ATP-dependent DNA helicase activity;0.0400315848027914!GO:0050681;androgen receptor binding;0.0406647672925598!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0408328911458159!GO:0006897;endocytosis;0.04137724374424!GO:0010324;membrane invagination;0.04137724374424!GO:0048144;fibroblast proliferation;0.0426970139960612!GO:0048145;regulation of fibroblast proliferation;0.0426970139960612!GO:0051540;metal cluster binding;0.0428838123561792!GO:0051536;iron-sulfur cluster binding;0.0428838123561792!GO:0048146;positive regulation of fibroblast proliferation;0.0428838123561792!GO:0006509;membrane protein ectodomain proteolysis;0.0443716362750982!GO:0033619;membrane protein proteolysis;0.0443716362750982!GO:0030911;TPR domain binding;0.044554058713319!GO:0006626;protein targeting to mitochondrion;0.0447101060741451!GO:0005092;GDP-dissociation inhibitor activity;0.0447995088147483!GO:0000209;protein polyubiquitination;0.0449078480356391!GO:0008180;signalosome;0.0450520212602528!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0451972116056833!GO:0008154;actin polymerization and/or depolymerization;0.0452908050635632!GO:0019752;carboxylic acid metabolic process;0.0456664834510121!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.0457304095602738!GO:0008097;5S rRNA binding;0.0457304095602738!GO:0008475;procollagen-lysine 5-dioxygenase activity;0.045780208388087!GO:0030032;lamellipodium biogenesis;0.0460531926777698!GO:0006749;glutathione metabolic process;0.0460983315795909!GO:0030833;regulation of actin filament polymerization;0.0466292889744345!GO:0004656;procollagen-proline 4-dioxygenase activity;0.0466941070320279!GO:0031545;peptidyl-proline 4-dioxygenase activity;0.0466941070320279!GO:0030865;cortical cytoskeleton organization and biogenesis;0.0474219003726613!GO:0031371;ubiquitin conjugating enzyme complex;0.0474876990834884!GO:0000086;G2/M transition of mitotic cell cycle;0.0475984183965349!GO:0006914;autophagy;0.0492720974647826!GO:0019798;procollagen-proline dioxygenase activity;0.0495150107038773!GO:0006518;peptide metabolic process;0.0497124572110264!GO:0007006;mitochondrial membrane organization and biogenesis;0.0497124572110264 | |||
|sample_id=10706 | |sample_id=10706 | ||
|sample_note= | |sample_note= | ||
Line 76: | Line 99: | ||
|sample_tissue=liver | |sample_tissue=liver | ||
|top_motifs=NKX2-1,4:1.79623562941;TEF:1.34093328081;DBP:1.26883133374;FOX{D1,D2}:1.20440373626;PITX1..3:1.18491227847;EVI1:1.17388949542;NFATC1..3:1.09385737397;EN1,2:1.06979032939;BPTF:1.02316127899;SMAD1..7,9:1.01839033567;HMGA1,2:1.01260796006;T:0.981228838467;SOX2:0.979590757757;TLX1..3_NFIC{dimer}:0.872868468797;ADNP_IRX_SIX_ZHX:0.819057899266;STAT5{A,B}:0.811596382481;FOXD3:0.806320638976;SP1:0.791675077694;NKX2-3_NKX2-5:0.772444447631;NKX6-1,2:0.713194749096;FOXP1:0.686213629027;PAX4:0.657314173997;LHX3,4:0.633170405011;NFY{A,B,C}:0.617854906773;TEAD1:0.588268999763;FOXL1:0.578950800933;NFE2:0.575416203832;PPARG:0.568858755599;ALX4:0.537262434705;TLX2:0.521211299412;HIF1A:0.520201023671;E2F1..5:0.514903036051;TAL1_TCF{3,4,12}:0.501631931057;TFAP2B:0.486628139176;NR1H4:0.48407446944;FOX{F1,F2,J1}:0.483282014531;FOX{I1,J2}:0.471037823155;MYB:0.465474171578;NR3C1:0.449194528314;NFIL3:0.431297183127;SOX17:0.427159863197;RFX1:0.393577719679;HOX{A5,B5}:0.379153332616;MAZ:0.372249041906;LEF1_TCF7_TCF7L1,2:0.371158472795;BACH2:0.367277395993;TFCP2:0.366455607213;IRF7:0.351443560518;HAND1,2:0.33818891811;MYOD1:0.331861005396;GFI1:0.331790088449;HBP1_HMGB_SSRP1_UBTF:0.327405567111;NANOG{mouse}:0.317842309194;FOXA2:0.315325911036;STAT2,4,6:0.311461750364;CDC5L:0.310627334911;POU6F1:0.30940012376;FOS_FOS{B,L1}_JUN{B,D}:0.29652248193;IRF1,2:0.295916305242;SOX{8,9,10}:0.274995381919;TFDP1:0.262542975553;IKZF2:0.261185672261;AHR_ARNT_ARNT2:0.258145268221;NFE2L2:0.240045529618;CEBPA,B_DDIT3:0.234219593704;RUNX1..3:0.221044954494;ELK1,4_GABP{A,B1}:0.201809362955;UFEwm:0.195637541616;ZNF143:0.193666172174;MZF1:0.191989453351;MTF1:0.185912805169;ZNF423:0.179629037896;GATA4:0.175273309865;XCPE1{core}:0.169083175454;MYBL2:0.162637095348;ZBTB16:0.146215218533;CRX:0.142071904795;NKX3-2:0.129819595144;FOSL2:0.127444532206;GTF2I:0.119169028272;HSF1,2:0.118884814263;EGR1..3:0.117931932504;SRF:0.0991053224763;HNF1A:0.0947817453267;HIC1:0.075845771674;TFAP4:0.0723828396515;HNF4A_NR2F1,2:0.0683206213096;GLI1..3:0.0620006093373;EP300:0.0580376288654;FOXQ1:0.0512110746337;HES1:0.0510853763868;FOXN1:0.0498000690889;HLF:0.0462143476831;MTE{core}:0.0446530889877;RBPJ:0.033869184087;PBX1:0.0329756335372;PDX1:0.0295871761952;PAX6:0.0253333815824;FOXP3:0.0221266218056;ESRRA:0.0144850537935;NRF1:0.00376275987092;PAX1,9:-0.00557383263637;IKZF1:-0.00961436608114;PAX2:-0.0323541327737;MED-1{core}:-0.0598810690463;FOXO1,3,4:-0.0685875568609;NR6A1:-0.072801329284;HOX{A4,D4}:-0.0806941871018;NFIX:-0.10071188754;NKX3-1:-0.103217256086;DMAP1_NCOR{1,2}_SMARC:-0.11421259137;RXR{A,B,G}:-0.11984647814;PAX3,7:-0.137164959109;NFKB1_REL_RELA:-0.13814982656;PATZ1:-0.1458964462;JUN:-0.146101569994;SREBF1,2:-0.152880018538;PRDM1:-0.161117990773;ATF5_CREB3:-0.168723430063;ZNF384:-0.174952053998;ELF1,2,4:-0.175272608571;GCM1,2:-0.175886760827;CUX2:-0.176433745764;ATF2:-0.183619184233;RFX2..5_RFXANK_RFXAP:-0.188319703536;SPIB:-0.191834098748;POU3F1..4:-0.196699555945;PAX5:-0.19695103592;MYFfamily:-0.198086100885;STAT1,3:-0.218128348409;AR:-0.218515575744;NKX2-2,8:-0.220922274283;GATA6:-0.223796788866;PAX8:-0.254756314884;ZBTB6:-0.272720018072;GFI1B:-0.2883773021;POU5F1:-0.294264571021;OCT4_SOX2{dimer}:-0.299083331127;ZIC1..3:-0.299384488725;ZFP161:-0.30013177218;XBP1:-0.300511591521;SOX5:-0.304974454461;ATF6:-0.305908653439;GTF2A1,2:-0.309452395843;TFAP2{A,C}:-0.316903243911;TBP:-0.322512058572;ARID5B:-0.325769644242;RORA:-0.373123977898;FOXM1:-0.376721064408;VSX1,2:-0.380649635945;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.38540381452;EBF1:-0.386571978528;ETS1,2:-0.386855036629;AIRE:-0.387718375769;TBX4,5:-0.390259293392;MEF2{A,B,C,D}:-0.402819065029;HOXA9_MEIS1:-0.421605831826;NFE2L1:-0.421627445546;bHLH_family:-0.429555503061;KLF4:-0.446044720831;ZNF148:-0.447943374245;PRRX1,2:-0.457542133423;YY1:-0.459621183183;NHLH1,2:-0.460406238714;ATF4:-0.464350808277;TP53:-0.472794884497;SNAI1..3:-0.478410104079;TOPORS:-0.47868344638;REST:-0.494205682203;SPI1:-0.499380205368;RXRA_VDR{dimer}:-0.50197695667;MAFB:-0.510922500498;CDX1,2,4:-0.512091259421;BREu{core}:-0.513516008452;ZNF238:-0.525908501591;ALX1:-0.555903009813;POU2F1..3:-0.565769181786;RREB1:-0.568250209067;GZF1:-0.605479559458;CREB1:-0.606904856465;ONECUT1,2:-0.627333112616;ZEB1:-0.63325380036;NR5A1,2:-0.6678577566;TGIF1:-0.698985294134;POU1F1:-0.808136580838;HMX1:-0.854933564671;HOX{A6,A7,B6,B7}:-0.932486011408;NANOG:-1.02156223805;ESR1:-1.17240076019;LMO2:-1.27125320785;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-1.32747351407;SPZ1:-1.38952850378 | |top_motifs=NKX2-1,4:1.79623562941;TEF:1.34093328081;DBP:1.26883133374;FOX{D1,D2}:1.20440373626;PITX1..3:1.18491227847;EVI1:1.17388949542;NFATC1..3:1.09385737397;EN1,2:1.06979032939;BPTF:1.02316127899;SMAD1..7,9:1.01839033567;HMGA1,2:1.01260796006;T:0.981228838467;SOX2:0.979590757757;TLX1..3_NFIC{dimer}:0.872868468797;ADNP_IRX_SIX_ZHX:0.819057899266;STAT5{A,B}:0.811596382481;FOXD3:0.806320638976;SP1:0.791675077694;NKX2-3_NKX2-5:0.772444447631;NKX6-1,2:0.713194749096;FOXP1:0.686213629027;PAX4:0.657314173997;LHX3,4:0.633170405011;NFY{A,B,C}:0.617854906773;TEAD1:0.588268999763;FOXL1:0.578950800933;NFE2:0.575416203832;PPARG:0.568858755599;ALX4:0.537262434705;TLX2:0.521211299412;HIF1A:0.520201023671;E2F1..5:0.514903036051;TAL1_TCF{3,4,12}:0.501631931057;TFAP2B:0.486628139176;NR1H4:0.48407446944;FOX{F1,F2,J1}:0.483282014531;FOX{I1,J2}:0.471037823155;MYB:0.465474171578;NR3C1:0.449194528314;NFIL3:0.431297183127;SOX17:0.427159863197;RFX1:0.393577719679;HOX{A5,B5}:0.379153332616;MAZ:0.372249041906;LEF1_TCF7_TCF7L1,2:0.371158472795;BACH2:0.367277395993;TFCP2:0.366455607213;IRF7:0.351443560518;HAND1,2:0.33818891811;MYOD1:0.331861005396;GFI1:0.331790088449;HBP1_HMGB_SSRP1_UBTF:0.327405567111;NANOG{mouse}:0.317842309194;FOXA2:0.315325911036;STAT2,4,6:0.311461750364;CDC5L:0.310627334911;POU6F1:0.30940012376;FOS_FOS{B,L1}_JUN{B,D}:0.29652248193;IRF1,2:0.295916305242;SOX{8,9,10}:0.274995381919;TFDP1:0.262542975553;IKZF2:0.261185672261;AHR_ARNT_ARNT2:0.258145268221;NFE2L2:0.240045529618;CEBPA,B_DDIT3:0.234219593704;RUNX1..3:0.221044954494;ELK1,4_GABP{A,B1}:0.201809362955;UFEwm:0.195637541616;ZNF143:0.193666172174;MZF1:0.191989453351;MTF1:0.185912805169;ZNF423:0.179629037896;GATA4:0.175273309865;XCPE1{core}:0.169083175454;MYBL2:0.162637095348;ZBTB16:0.146215218533;CRX:0.142071904795;NKX3-2:0.129819595144;FOSL2:0.127444532206;GTF2I:0.119169028272;HSF1,2:0.118884814263;EGR1..3:0.117931932504;SRF:0.0991053224763;HNF1A:0.0947817453267;HIC1:0.075845771674;TFAP4:0.0723828396515;HNF4A_NR2F1,2:0.0683206213096;GLI1..3:0.0620006093373;EP300:0.0580376288654;FOXQ1:0.0512110746337;HES1:0.0510853763868;FOXN1:0.0498000690889;HLF:0.0462143476831;MTE{core}:0.0446530889877;RBPJ:0.033869184087;PBX1:0.0329756335372;PDX1:0.0295871761952;PAX6:0.0253333815824;FOXP3:0.0221266218056;ESRRA:0.0144850537935;NRF1:0.00376275987092;PAX1,9:-0.00557383263637;IKZF1:-0.00961436608114;PAX2:-0.0323541327737;MED-1{core}:-0.0598810690463;FOXO1,3,4:-0.0685875568609;NR6A1:-0.072801329284;HOX{A4,D4}:-0.0806941871018;NFIX:-0.10071188754;NKX3-1:-0.103217256086;DMAP1_NCOR{1,2}_SMARC:-0.11421259137;RXR{A,B,G}:-0.11984647814;PAX3,7:-0.137164959109;NFKB1_REL_RELA:-0.13814982656;PATZ1:-0.1458964462;JUN:-0.146101569994;SREBF1,2:-0.152880018538;PRDM1:-0.161117990773;ATF5_CREB3:-0.168723430063;ZNF384:-0.174952053998;ELF1,2,4:-0.175272608571;GCM1,2:-0.175886760827;CUX2:-0.176433745764;ATF2:-0.183619184233;RFX2..5_RFXANK_RFXAP:-0.188319703536;SPIB:-0.191834098748;POU3F1..4:-0.196699555945;PAX5:-0.19695103592;MYFfamily:-0.198086100885;STAT1,3:-0.218128348409;AR:-0.218515575744;NKX2-2,8:-0.220922274283;GATA6:-0.223796788866;PAX8:-0.254756314884;ZBTB6:-0.272720018072;GFI1B:-0.2883773021;POU5F1:-0.294264571021;OCT4_SOX2{dimer}:-0.299083331127;ZIC1..3:-0.299384488725;ZFP161:-0.30013177218;XBP1:-0.300511591521;SOX5:-0.304974454461;ATF6:-0.305908653439;GTF2A1,2:-0.309452395843;TFAP2{A,C}:-0.316903243911;TBP:-0.322512058572;ARID5B:-0.325769644242;RORA:-0.373123977898;FOXM1:-0.376721064408;VSX1,2:-0.380649635945;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.38540381452;EBF1:-0.386571978528;ETS1,2:-0.386855036629;AIRE:-0.387718375769;TBX4,5:-0.390259293392;MEF2{A,B,C,D}:-0.402819065029;HOXA9_MEIS1:-0.421605831826;NFE2L1:-0.421627445546;bHLH_family:-0.429555503061;KLF4:-0.446044720831;ZNF148:-0.447943374245;PRRX1,2:-0.457542133423;YY1:-0.459621183183;NHLH1,2:-0.460406238714;ATF4:-0.464350808277;TP53:-0.472794884497;SNAI1..3:-0.478410104079;TOPORS:-0.47868344638;REST:-0.494205682203;SPI1:-0.499380205368;RXRA_VDR{dimer}:-0.50197695667;MAFB:-0.510922500498;CDX1,2,4:-0.512091259421;BREu{core}:-0.513516008452;ZNF238:-0.525908501591;ALX1:-0.555903009813;POU2F1..3:-0.565769181786;RREB1:-0.568250209067;GZF1:-0.605479559458;CREB1:-0.606904856465;ONECUT1,2:-0.627333112616;ZEB1:-0.63325380036;NR5A1,2:-0.6678577566;TGIF1:-0.698985294134;POU1F1:-0.808136580838;HMX1:-0.854933564671;HOX{A6,A7,B6,B7}:-0.932486011408;NANOG:-1.02156223805;ESR1:-1.17240076019;LMO2:-1.27125320785;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-1.32747351407;SPZ1:-1.38952850378 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10706-109H4;search_select_hide=table117:FF:10706-109H4 | |||
}} | }} |
Latest revision as of 14:34, 3 June 2020
Name: | pleomorphic hepatocellular carcinoma cell line:SNU-387 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11933 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11933
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11933
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.858 |
10 | 10 | 0.117 |
100 | 100 | 0.238 |
101 | 101 | 0.58 |
102 | 102 | 0.363 |
103 | 103 | 0.259 |
104 | 104 | 0.72 |
105 | 105 | 0.404 |
106 | 106 | 0.253 |
107 | 107 | 0.315 |
108 | 108 | 0.139 |
109 | 109 | 0.887 |
11 | 11 | 0.364 |
110 | 110 | 0.854 |
111 | 111 | 0.456 |
112 | 112 | 0.108 |
113 | 113 | 0.172 |
114 | 114 | 0.149 |
115 | 115 | 0.442 |
116 | 116 | 0.642 |
117 | 117 | 0.646 |
118 | 118 | 0.774 |
119 | 119 | 0.839 |
12 | 12 | 0.418 |
120 | 120 | 0.684 |
121 | 121 | 0.276 |
122 | 122 | 0.228 |
123 | 123 | 0.566 |
124 | 124 | 0.112 |
125 | 125 | 0.718 |
126 | 126 | 0.162 |
127 | 127 | 0.643 |
128 | 128 | 0.4 |
129 | 129 | 0.92 |
13 | 13 | 0.491 |
130 | 130 | 0.345 |
131 | 131 | 0.809 |
132 | 132 | 0.455 |
133 | 133 | 0.339 |
134 | 134 | 0.415 |
135 | 135 | 0.341 |
136 | 136 | 0.243 |
137 | 137 | 0.453 |
138 | 138 | 0.817 |
139 | 139 | 0.139 |
14 | 14 | 0.522 |
140 | 140 | 0.0657 |
141 | 141 | 0.721 |
142 | 142 | 0.51 |
143 | 143 | 0.299 |
144 | 144 | 0.848 |
145 | 145 | 0.197 |
146 | 146 | 0.536 |
147 | 147 | 0.887 |
148 | 148 | 0.195 |
149 | 149 | 0.924 |
15 | 15 | 0.0347 |
150 | 150 | 0.311 |
151 | 151 | 0.917 |
152 | 152 | 0.656 |
153 | 153 | 0.275 |
154 | 154 | 0.411 |
155 | 155 | 0.236 |
156 | 156 | 0.813 |
157 | 157 | 0.171 |
158 | 158 | 0.0831 |
159 | 159 | 0.523 |
16 | 16 | 0.812 |
160 | 160 | 0.37 |
161 | 161 | 0.182 |
162 | 162 | 0.763 |
163 | 163 | 0.175 |
164 | 164 | 0.437 |
165 | 165 | 0.179 |
166 | 166 | 0.309 |
167 | 167 | 0.531 |
168 | 168 | 0.244 |
169 | 169 | 0.572 |
17 | 17 | 0.0832 |
18 | 18 | 0.0752 |
19 | 19 | 0.318 |
2 | 2 | 0.344 |
20 | 20 | 0.287 |
21 | 21 | 0.0899 |
22 | 22 | 0.992 |
23 | 23 | 0.381 |
24 | 24 | 0.46 |
25 | 25 | 0.179 |
26 | 26 | 0.679 |
27 | 27 | 0.431 |
28 | 28 | 0.177 |
29 | 29 | 0.402 |
3 | 3 | 0.62 |
30 | 30 | 0.453 |
31 | 31 | 0.729 |
32 | 32 | 0.11 |
33 | 33 | 0.997 |
34 | 34 | 0.177 |
35 | 35 | 0.0957 |
36 | 36 | 0.439 |
37 | 37 | 0.143 |
38 | 38 | 0.271 |
39 | 39 | 0.923 |
4 | 4 | 0.467 |
40 | 40 | 0.0725 |
41 | 41 | 0.295 |
42 | 42 | 0.447 |
43 | 43 | 0.535 |
44 | 44 | 0.166 |
45 | 45 | 0.323 |
46 | 46 | 0.299 |
47 | 47 | 0.182 |
48 | 48 | 0.619 |
49 | 49 | 0.462 |
5 | 5 | 0.0291 |
50 | 50 | 0.946 |
51 | 51 | 0.234 |
52 | 52 | 0.824 |
53 | 53 | 0.475 |
54 | 54 | 0.915 |
55 | 55 | 0.0561 |
56 | 56 | 0.999 |
57 | 57 | 0.812 |
58 | 58 | 0.437 |
59 | 59 | 0.233 |
6 | 6 | 0.662 |
60 | 60 | 0.784 |
61 | 61 | 0.467 |
62 | 62 | 0.441 |
63 | 63 | 0.869 |
64 | 64 | 0.872 |
65 | 65 | 0.263 |
66 | 66 | 0.0637 |
67 | 67 | 0.506 |
68 | 68 | 0.16 |
69 | 69 | 0.197 |
7 | 7 | 0.829 |
70 | 70 | 0.0573 |
71 | 71 | 0.599 |
72 | 72 | 0.172 |
73 | 73 | 0.834 |
74 | 74 | 0.223 |
75 | 75 | 0.361 |
76 | 76 | 0.511 |
77 | 77 | 0.743 |
78 | 78 | 0.324 |
79 | 79 | 0.963 |
8 | 8 | 0.637 |
80 | 80 | 0.795 |
81 | 81 | 0.101 |
82 | 82 | 0.231 |
83 | 83 | 0.481 |
84 | 84 | 0.486 |
85 | 85 | 0.705 |
86 | 86 | 0.706 |
87 | 87 | 0.225 |
88 | 88 | 0.881 |
89 | 89 | 0.133 |
9 | 9 | 0.697 |
90 | 90 | 0.653 |
91 | 91 | 0.307 |
92 | 92 | 0.599 |
93 | 93 | 0.398 |
94 | 94 | 0.11 |
95 | 95 | 0.00204 |
96 | 96 | 0.742 |
97 | 97 | 0.203 |
98 | 98 | 0.00389 |
99 | 99 | 0.528 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11933
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
DOID:5662 pleomorphic carcinoma
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0103191 SNU-387 cell sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000066 (epithelial cell)
0002371 (somatic cell)
0000181 (metabolising cell)
0000417 (endopolyploid cell)
0000668 (parenchymal cell)
0000412 (polyploid cell)
0000255 (eukaryotic cell)
0000182 (hepatocyte)
DOID: Disease
4 (disease)
162 (cancer)
14566 (disease of cellular proliferation)
0050687 (cell type cancer)
7 (disease of anatomical entity)
305 (carcinoma)
5662 (pleomorphic carcinoma)
UBERON: Anatomy
0000468 (multi-cellular organism)
0002107 (liver)
0002100 (trunk)
0001007 (digestive system)
0004119 (endoderm-derived structure)
0000062 (organ)
0000475 (organism subdivision)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0009569 (subdivision of trunk)
0002368 (endocrine gland)
0005177 (trunk region element)
0002365 (exocrine gland)
0005172 (abdomen element)
0006925 (digestive gland)
0002530 (gland)
0010317 (germ layer / neural crest derived structure)
0005173 (abdominal segment element)
0002417 (abdominal segment of trunk)
0000949 (endocrine system)
0002330 (exocrine system)
0000916 (abdomen)
0002423 (hepatobiliary system)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100297 (carcinoma cell line sample)
0101120 (epithelial cell line sample)
0100224 (liver cell line sample)
0100578 (hepatoma cell line sample)
0103191 (SNU-387 cell sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000223 (endodermal cell)
UBERON:0001041 (foregut)
UBERON:0002532 (epiblast (generic))
UBERON:0006595 (presumptive endoderm)
UBERON:0003104 (mesenchyme)
UBERON:0004161 (septum transversum)
UBERON:0009497 (epithelium of foregut-midgut junction)
UBERON:0010316 (germ layer / neural crest)