FF:10823-111C4: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00004741 | ||
| | |accession_numbers=CAGE;DRX007778;DRR008650;DRZ000075;DRZ001460;DRZ011425;DRZ012810 | ||
| | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0002371,CL:0000542,CL:0000219,CL:0000945,CL:0000738,CL:0002087,CL:0002242,CL:0000255 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0101035,FF:0100773,FF:0101522,FF:0102062 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr6:391743..391759,+!p1@IRF4!2.60!396.47!IRF4;;chr2:68592406..68592424,+!p1@PLEK!2.42!264.31!PLEK;;chr11:111249993..111250006,-!p1@POU2AF1!2.40!250.46!POU2AF1;;chr19:50922187..50922204,+!p1@SPIB!2.08!119.64!SPIB;;chr16:85932760..85932775,+!p1@IRF8!2.02!104.92!IRF8;;chr1:25291475..25291511,-!p2@RUNX3!2.01!101.46!RUNX3;;chr12:103351444..103351461,+!p1@ASCL1!1.98!94.85!ASCL1;;chr3:27763807..27763822,-!p1@EOMES!1.91!80.99!EOMES;;chr17:38020392..38020477,-!p1@IKZF3!1.87!73.83!IKZF3;;chr2:231090433..231090469,+!p1@SP140!1.85!69.11!SP140;;chr2:231090471..231090504,+!p2@SP140!1.77!57.54!SP140;;chr1:25256756..25256774,-!p1@RUNX3!1.69!88.23!RUNX3;;chr7:28610099..28610113,+!p5@CREB5!1.67!45.57!CREB5;;chr2:68592394..68592405,+!p2@PLEK!1.60!38.96!PLEK;;chr10:64576105..64576133,-!p1@EGR2!1.57!72.57!EGR2;;chr19:36204309..36204335,+!p1@ZBTB32!1.57!36.21!ZBTB32;;chr1:158978768..158978800,+!p8@IFI16!1.53!32.74!IFI16;;chr3:189349162..189349207,+!p2@TP63!1.53!32.74!TP63;;chr8:76319876..76319926,+!p1@HNF4G!1.51!31.33!HNF4G;;chr3:27764190..27764208,-!p2@EOMES!1.50!30.93!EOMES;;chr5:88120151..88120177,-!p6@MEF2C!1.46!27.86!MEF2C;;chr12:103352277..103352324,+!p2@ASCL1!1.46!27.78!ASCL1;;chr17:36105042..36105060,-!p1@HNF1B!1.46!27.63!HNF1B;;chr14:75988771..75988826,+!p1@BATF!1.45!36.21!BATF;;chr1:3569072..3569093,+!p1@TP73!1.44!26.76!TP73;;chr20:50159198..50159299,-!p1@NFATC2!1.42!36.84!NFATC2;;chr19:42636586..42636607,-!p1@POU2F2!1.38!62.73!POU2F2;;chrX:2418949..2419024,-!p1@DHRSX,p1@ZBED1!1.38!23.14!ZBED1;;chr7:50348268..50348366,+!p4@IKZF1!1.38!22.90!IKZF1;;chr17:45810594..45810608,+!p1@TBX21!1.37!22.20!TBX21;;chr9:37034469..37034474,-!p1@PAX5!1.36!22.04!PAX5;;chr11:61520075..61520136,+!p1@C11orf9!1.32!41.24!C11orf9;;chr4:185395590..185395627,-!p3@IRF2!1.32!24.79!IRF2;;chr8:72756637..72756664,-!p3@MSC!1.32!22.75!MSC;;chr11:47400078..47400106,-!p1@SPI1!1.32!20.07!SPI1;;chr19:19281060..19281078,-!p2@MEF2BNB-MEF2B,p2@MEF2B!1.32!19.99!MEF2B;;chr18:52989031..52989079,-!p2@TCF4!1.28!41.80!TCF4;;chr8:72756667..72756736,-!p2@MSC!1.23!24.95!MSC;;chr8:76319850..76319870,+!p4@HNF4G!1.23!16.06!HNF4G;;chr5:158526917..158526932,-!p1@EBF1!1.22!38.25!EBF1;;chr3:101546827..101546847,+!p2@NFKBIZ!1.21!21.17!NFKBIZ;;chr5:142780237..142780261,-!p7@NR3C1!1.21!15.03!NR3C1;;chr7:28610060..28610073,+!p9@CREB5!1.20!14.72!CREB5;;chr8:135614084..135614119,-!p4@ZFAT!1.19!14.33!ZFAT;;chr9:1050331..1050363,+!p1@DMRT2!1.16!13.46!DMRT2;;chr13:41593425..41593480,-!p1@ELF1!1.15!82.65!ELF1;;chr5:88178983..88179012,-!p1@MEF2C!1.14!99.18!MEF2C;;chr6:34204973..34204990,+!p4@HMGA1!1.13!166.32!HMGA1;;chr5:133450365..133450444,+!p1@TCF7!1.13!56.51!TCF7;;chr14:75988831..75988847,+!p2@BATF!1.13!12.52!BATF;;chr2:68615031..68615055,+!p3@PLEK!1.13!12.36!PLEK;;chr11:19262421..19262455,-!p3@E2F8!1.12!12.20!E2F8;;chr2:214015343..214015366,-!p3@IKZF2!1.10!11.49!IKZF2;;chr3:141105705..141105770,+!p4@ZBTB38!1.09!13.77!ZBTB38;;chr2:214015111..214015179,-!p1@IKZF2!1.07!19.52!IKZF2;;chr12:54447599..54447630,+!p3@HOXC4!1.07!13.38!HOXC4;;chr2:231090344..231090361,-!p3@SP110!1.07!10.86!SP110;;chr7:50344251..50344288,+!p3@IKZF1!1.06!10.39!IKZF1;;chr19:45579725..45579743,-!p1@ZNF296!1.05!46.83!ZNF296;;chr17:1959369..1959388,+!p2@HIC1!1.04!26.76!HIC1;;chr7:128577972..128578047,+!p1@IRF5!1.04!15.98!IRF5;;chr3:141747950..141748004,-!p7@TFDP2!1.04!10.07!TFDP2;;chr9:117150254..117150271,-!p1@AKNA!1.03!27.08!AKNA;;chr6:135502408..135502459,+!p2@MYB!1.03!11.41!MYB;;chr1:25291620..25291635,-!p4@RUNX3!1.02!9.37!RUNX3;;chr16:85936539..85936562,+!p3@IRF8!1.02!9.37!IRF8;;chr11:615570..615721,-!p2@IRF7!1.01!18.58!IRF7;;chr17:37934204..37934241,-!p3@IKZF3!1.00!9.05!IKZF3;;chr1:167298300..167298319,+!p2@POU2F1!1.00!9.05!POU2F1;;chr1:170632115..170632136,+!p9@PRRX1!1.00!9.05!PRRX1;;chr20:42543441..42543497,+!p1@TOX2!0.99!40.61!TOX2;;chr7:50344289..50344323,+!p1@IKZF1!0.99!8.82!IKZF1;;chr16:85936412..85936431,+!p2@IRF8!0.99!8.74!IRF8;;chr8:72756063..72756125,-!p1@MSC!0.98!17.47!MSC;;chr1:23857698..23857733,-!p1@E2F2!0.98!15.98!E2F2;;chr9:126774018..126774055,+!p1@LHX2!0.98!8.66!LHX2;;chr7:50343634..50343717,+!p2@IKZF1!0.98!8.58!IKZF1;;chr7:137620650..137620677,-!p3@CREB3L2!0.98!8.50!CREB3L2;;chr9:126773880..126773895,+!p2@LHX2!0.98!8.50!LHX2;;chr20:42295713..42295738,+!p2@MYBL2!0.97!50.69!MYBL2;;chr1:38512457..38512474,-!p1@POU3F1!0.96!8.97!POU3F1;;chr7:137620684..137620711,-!p4@CREB3L2!0.96!8.19!CREB3L2;;chr1:158979686..158979745,+!p1@IFI16!0.95!269.27!IFI16;;chr4:185395633..185395651,-!p2@IRF2!0.95!12.75!IRF2;;chr10:104155480..104155534,+!p2@NFKB2!0.94!51.32!NFKB2;;chr2:214016254..214016282,-!p7@IKZF2!0.94!7.71!IKZF2;;chr19:42627037..42627084,-!p3@POU2F2!0.94!7.71!POU2F2;;chr1:151319654..151319698,-!p2@RFX5!0.93!17.00!RFX5;;chr5:142780189..142780223,-!p6@NR3C1!0.93!7.56!NR3C1;;chr1:92951607..92951661,-!p1@GFI1!0.93!7.48!GFI1;;chr17:36105074..36105086,-!p2@HNF1B!0.92!7.40!HNF1B;;chr17:38020557..38020572,-!p4@IKZF3!0.92!7.40!IKZF3;;chr18:52989001..52989030,-!p10@TCF4!0.91!8.03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| |||
|ffid_belonging_in_development=CL:0000134,CL:0000051 | |||
|fonse_cell_line=FF:0101035,FF:0101522 | |fonse_cell_line=FF:0101035,FF:0101522 | ||
|fonse_cell_line_closure=FF:0101035,FF:0101522 | |fonse_cell_line_closure=FF:0101035,FF:0101522 | ||
Line 66: | Line 40: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/B%2520lymphoblastoid%2520cell%2520line%253a%2520GM12878%2520ENCODE%252c%2520biol_rep3.CNhs12333.10823-111C4.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/B%2520lymphoblastoid%2520cell%2520line%253a%2520GM12878%2520ENCODE%252c%2520biol_rep3.CNhs12333.10823-111C4.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/B%2520lymphoblastoid%2520cell%2520line%253a%2520GM12878%2520ENCODE%252c%2520biol_rep3.CNhs12333.10823-111C4.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/B%2520lymphoblastoid%2520cell%2520line%253a%2520GM12878%2520ENCODE%252c%2520biol_rep3.CNhs12333.10823-111C4.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/B%2520lymphoblastoid%2520cell%2520line%253a%2520GM12878%2520ENCODE%252c%2520biol_rep3.CNhs12333.10823-111C4.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10823-111C4 | |||
|is_a=EFO:0002091;;FF:0000210;;FF:0102062 | |||
|is_obsolete= | |||
|library_id=CNhs12333 | |||
|library_id_phase_based=2:CNhs12333 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10823 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10823 | |||
|name=B lymphoblastoid cell line: GM12878 ENCODE, biol_rep3 | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs12333,LSID913,release011,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,0.0722707781238188,0.144123773101263,-0.241928278839652,0.50525786819822,0,0,0,0,0,0,0,0,0,0,1.06247836898485,0,0,-0.0898314413904983,0,0,0,0,0.28881450836592,0.134630911942147,0,0,0.315803506705558,0,0,0,0,0,0,0.0317457844789647,0,0,0,0.0329050193664387,0,-0.0542723515594448,0.144123773101263,0,0,0,0,0,0,0,-0.007762511429615,0,0,0,0.118873939973783,0,-0.0526759682156587,0.0329050193664387,0.397884216972036,0,0,0.154807126321082,0,0,0,0,0,0,0,0,0.0329050193664387,0,0.0634915689579293,0.0164525096832193,0,0.0634915689579293,0,0,0,0,0,0,0,0.0061305333018159,0.0329050193664387,0,-0.552571649267773,0,0,0,0.0487058024556651,-0.0319019903918055,0,0,0,0,0.134553456972498,0.334387386967587,0,0,0,0.0329050193664387,0,0.0317457844789647,0,0,0,0,0,0,0,0,0,0,0.252150753534179,0.63790782088357,0.368859976634756,0,0,-0.0541325136738031,-0.145060096072327,0,0,0.118873939973783,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0.526510303957951,0.134553456972498,0,0,0.212104001466496,0,0,0,0,0,0,0,0,-0.247178875285564,0,-0.44118119938557,0.089073665686733,0.0164525096832193,0.0329050193664387,0.164228466452984,0,0,0,0,0.167985895703078,0,0.0634915689579293,0.0920649700783706,0,-0.128119866952565,0.0920649700783706,-0.0504125515893149,0,0,0,0,-0.0186252810838506,-0.213407260820037,0.0329050193664387,-0.142512276670545,-0.0683442610773682,0,0.0634915689579293,0,0,0.0826904408961872,0,0.453716271438697,-0.0827201683234173,0.0492578287680654,-0.658370722976243,-0.0138996395259413,0,0,0,-0.0119663913530909,0.0166041990975876,0,0,-0.121779851751874,0.50294021685069,0,0.0329050193664387,-0.391044581551635,0,-0.137842442588235,-0.182179884744404,0,0.265176266211241,0.0329050193664387,0,0.0329050193664387,0,0,0,0,0.0329050193664387,0.118873939973783,0,0,-0.0574934668214365,0.238406584075395,0.016152484615171,0,0,0,-0.149110064307949,0,0,-0.281221185878196,-0.101646080781783,0.0688842768284215,0.392956978653547,0,0.347263858710868,-0.0136996840966775,0.0370428268779283,0.130916761620572,-0.147401849371139,-0.189981719549847,0,-0.0763969789704732,-0.753367609747573,0.0268470161271601,0.101083192481099,0,-1.2314085082871,-0.300482483554581,0,0,-0.0140173575213738,-0.107898076403635,0,0.0329050193664387,-0.490114714476774,-0.05883291353318,-0.493223639318051,-0.835468498825238,-0.208051842785941,0.0870723862389682,-0.0395325284566706,-0.151389016639212,-0.0351022112668111,-0.29549694813661,0.00421529803287224,0,-0.0548464063362842,-0.0248596863436107,0.0910555633604044,0.320433442112724,0,0.0322421780381689,-0.0683442610773682,0,-0.673823191925715,0.0203947552262478,0,0,0.022305551353502,0.0329050193664387,0.0329050193664387,0.353987838623061,0,0,-0.00335393613744639,0.17413878046356,0.239574610489032,0,-0.058924362977712,-0.100027997638916,0.179781204614684,0,0.00971953206046794,-0.0825183284994649,0.0401196945259444,-0.183971394638837,0,0.208330108867772,0.0841945557756857,-0.164990696339003,-0.231789876486689,-0.0584468268118252,0.201810770648368,0.135600398191273,0.156660012813125,-0.788939864790226,0,-0.0881268324752877,-0.144941073228965,-0.850639731151941,0.0840315094079678,0.0336596917501605,-0.583529904229572,0,-0.742525919165823,0,0,0,0.35790751909837,-0.372447855770162,0.829113164769172,0.176045527761961,0,-0.137619359263851,0.421147584445678,0,-0.104398477468903,0,0,-0.117462063968201,-0.697695966512583,0.598192032886017,0.0728731447118839,0,-0.698015188311286,0,0,-0.205054659285191,0.188249165017768,0,-0.258663344267935,-0.125404538081873,-0.143459667504402,-0.0239061033565634,0,0,-0.645700337992725,0,0,-0.60592806381803,-0.132606049043025,-0.619783323958633,0.778491454667813,-0.00290128758159025,0.0952214147155959,0,0.338588299847423,-0.085462795886805,0.190604928905049,0.070188105573761,0,0,0.158928739960764,-0.0710137877630395,0,0,0,-0.0339544030833233,0,0,0,0,0.0161871873141312,0,0,-0.218529470497884,0.237598698260837,0,-0.0323748419068837,0,0,0,0,0,0,0,0,0.236534554281324,0,-0.0595258467184909,0.116294404105103,0,0.0329050193664387,0,-0.0477375068503968,0.180003083417417,0,0.0122610666036318,0,0.0624849947224047,0.0329050193664387,0,0.0579827833120521,0,0,0.0164525096832193,0.0317457844789647,0.0863933160475995,-0.0498738589067776,0.0329050193664387,0,0,0.576709803856803,0.0329050193664387,0,0,0,0.133156507402252,0,0,0,0.0329050193664387,0.137421149618789,-0.0486768601804027,0,0.19359906716828,-0.0828270772603301,-0.140110877853251,0,0,-0.0933612360868097,0,0,0.173334200586404,-0.0494652035992276,0.0920649700783706,-0.0209247759461169,0,0,0.0317457844789647,0,0.0329050193664387,0,0.457728521336679,0,0,0,0,0,0,0,0,0,0,0,-0.24932691321279,0.159926696875669,-0.0145835034507642,0,0,0,0,0,0,-0.00765351339568375,0.00160426679046749,0.0223253808298935,0,0,0,0,0.0329050193664387,0,0,0.214926809379333,0,0,0,0,0,0.397884216972036,0.0283972292404836,0.0920649700783706,0,0,0.777926928186235,0.00166116261247334,0,-0.00649271532264184,0,0.0329050193664387,0,0,0.0329050193664387,0.0329050193664387,0.0561149793156775,0.048198294162184,0,0,0.0329050193664387,0,0,0.0208046870658157,-0.272304461075635,0,0.0920649700783706,0.00433722714005447,0,0,0.144123773101263,0.0329050193664387,-0.241928278839652,0,0.232588808210205,0,0,0.0302393993922863,0,0,0,-0.104796384789156,0,0.0722707781238188,0,0.0634915689579293,0,0,0,0.0634915689579293,0,0.0329050193664387,0,0,0,0,0,0,0,0,0,0.0594369699868915,0,0,0,-0.574061911570411,0,-0.28720751597291,-0.0624427054186733,0,0,-0.232628352633041,0,0,0,0,0,0,0.000405360450437611,0,0,0,0,0,0,0,0,0,0,0,0,0.0164525096832193,0,0,0.0364346269227786,0,0,0.368859976634756,0,0,0,0,0,0.0164525096832193,-0.0031122593261237,0,0,0,0,0,0,0,0.134630911942147,0,0,0.0493021396911837,0,0,0.0269911469650766,0.0329050193664387,0,0,0.0209651080410225,-0.251474615344183,-0.00477960064767319,0,0,0,-0.054385572482455,0.118873939973783,0,-0.0591870025110841,0.0329050193664387,0.0773463856823621,0.4837983761315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| |||
|rna_box=111 | |||
|rna_catalog_number= | |||
|rna_concentration=0.70694 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=2.19 | |||
|rna_od260/280=2.02 | |||
|rna_position=C4 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=111C4 | |||
|rna_weight_ug=35.347 | |||
|sample_age= | |||
|sample_category=cell lines | |||
|sample_cell_catalog= | |||
|sample_cell_line=GM12878 | |||
|sample_cell_lot= | |||
|sample_cell_type=b cell | |||
|sample_collaboration=Carrie Davis (Cold spring Harbor Laboratories) | |||
|sample_company= | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease= | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;7.76857074352508e-278!GO:0043227;membrane-bound organelle;3.69786069478295e-233!GO:0043231;intracellular membrane-bound organelle;1.00884902853795e-232!GO:0043226;organelle;9.95552307287824e-229!GO:0043229;intracellular organelle;8.45410604405785e-228!GO:0005737;cytoplasm;1.67446210394911e-168!GO:0044422;organelle part;1.04111525780962e-164!GO:0044446;intracellular organelle part;6.79915337870459e-163!GO:0005634;nucleus;7.23620141184493e-129!GO:0032991;macromolecular complex;1.87727973866236e-124!GO:0044237;cellular metabolic process;7.84323667302407e-114!GO:0044238;primary metabolic process;1.50069279504815e-111!GO:0044444;cytoplasmic part;1.74289337598101e-107!GO:0043170;macromolecule metabolic process;3.72956800736387e-107!GO:0044428;nuclear part;1.18024687160989e-106!GO:0030529;ribonucleoprotein complex;7.7307267263896e-104!GO:0003723;RNA binding;9.86368966857138e-96!GO:0043233;organelle lumen;2.42875062660933e-93!GO:0031974;membrane-enclosed lumen;2.42875062660933e-93!GO:0005739;mitochondrion;2.22963036994875e-75!GO:0043283;biopolymer metabolic process;2.27664969129155e-75!GO:0005515;protein binding;9.61593199456908e-75!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.78844045720287e-74!GO:0006396;RNA processing;1.99113901542913e-69!GO:0010467;gene expression;2.20254696602154e-68!GO:0043234;protein complex;4.9093038249514e-63!GO:0006412;translation;5.39774637704386e-63!GO:0031981;nuclear lumen;4.81891876580597e-62!GO:0005840;ribosome;1.20962657153581e-55!GO:0016071;mRNA metabolic process;9.81415781915374e-55!GO:0044429;mitochondrial part;9.24611105961248e-53!GO:0006259;DNA metabolic process;4.81177116916574e-52!GO:0031967;organelle envelope;6.87458356735528e-50!GO:0031975;envelope;1.87630786384705e-49!GO:0003676;nucleic acid binding;1.57723780826007e-48!GO:0008380;RNA splicing;1.07151600973586e-47!GO:0003735;structural constituent of ribosome;1.17275002667061e-47!GO:0019538;protein metabolic process;2.46524446478446e-47!GO:0006397;mRNA processing;9.05145264953624e-47!GO:0006996;organelle organization and biogenesis;1.40169533062838e-45!GO:0016043;cellular component organization and biogenesis;1.19196374259429e-44!GO:0031090;organelle membrane;3.90794639424542e-44!GO:0044249;cellular biosynthetic process;1.59419790412401e-43!GO:0044267;cellular protein metabolic process;1.56094429408227e-42!GO:0009059;macromolecule biosynthetic process;2.21066286552797e-42!GO:0043228;non-membrane-bound organelle;6.47638766685249e-42!GO:0043232;intracellular non-membrane-bound organelle;6.47638766685249e-42!GO:0044260;cellular macromolecule metabolic process;1.64084047282516e-41!GO:0033036;macromolecule localization;6.03476437255573e-41!GO:0009058;biosynthetic process;6.10305890090213e-41!GO:0033279;ribosomal subunit;1.1973669437047e-40!GO:0022613;ribonucleoprotein complex biogenesis and assembly;4.54995668357019e-40!GO:0007049;cell cycle;5.06662818210046e-40!GO:0015031;protein transport;3.67617691273202e-39!GO:0005829;cytosol;9.94758473577577e-39!GO:0005654;nucleoplasm;1.39247772310397e-38!GO:0045184;establishment of protein localization;4.66683300394494e-37!GO:0000166;nucleotide binding;9.26782871458329e-37!GO:0008104;protein localization;1.43600398783245e-36!GO:0016070;RNA metabolic process;3.05233094851605e-36!GO:0046907;intracellular transport;4.02721141077915e-36!GO:0005681;spliceosome;4.72959165269296e-36!GO:0065003;macromolecular complex assembly;9.43812533107971e-36!GO:0006974;response to DNA damage stimulus;5.04983971934089e-34!GO:0022402;cell cycle process;1.54368682385026e-32!GO:0005740;mitochondrial envelope;4.86134120639484e-32!GO:0022607;cellular component assembly;6.56346242408811e-31!GO:0005694;chromosome;8.84022797735697e-31!GO:0019866;organelle inner membrane;2.34320184021034e-30!GO:0031966;mitochondrial membrane;6.2530231382391e-30!GO:0006886;intracellular protein transport;8.44144549227529e-30!GO:0000278;mitotic cell cycle;2.28785218010544e-29!GO:0044451;nucleoplasm part;2.8391034130914e-29!GO:0006281;DNA repair;6.28630264257655e-29!GO:0005830;cytosolic ribosome (sensu Eukaryota);2.15161917924956e-28!GO:0005743;mitochondrial inner membrane;6.63067919562258e-28!GO:0044427;chromosomal part;2.74676977513398e-27!GO:0051649;establishment of cellular localization;4.42201045078366e-27!GO:0022403;cell cycle phase;1.23545411508215e-26!GO:0044445;cytosolic part;1.73459945220223e-26!GO:0051641;cellular localization;2.79223180253467e-26!GO:0000087;M phase of mitotic cell cycle;7.91222341004832e-26!GO:0007067;mitosis;1.26219574199484e-25!GO:0032553;ribonucleotide binding;1.88235689052697e-25!GO:0032555;purine ribonucleotide binding;1.88235689052697e-25!GO:0017076;purine nucleotide binding;2.31984620354894e-25!GO:0005730;nucleolus;7.78002298218362e-25!GO:0031980;mitochondrial lumen;3.18973771034879e-24!GO:0005759;mitochondrial matrix;3.18973771034879e-24!GO:0051276;chromosome organization and biogenesis;3.46708902638233e-24!GO:0051301;cell division;5.63449311952122e-24!GO:0000279;M phase;6.17318020345187e-24!GO:0016462;pyrophosphatase activity;7.65287820700385e-24!GO:0017111;nucleoside-triphosphatase activity;8.93767752909639e-24!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.1536132690109e-23!GO:0016817;hydrolase activity, acting on acid anhydrides;1.53344113224829e-23!GO:0005524;ATP binding;1.60406880819647e-23!GO:0032559;adenyl ribonucleotide binding;6.95766400204708e-23!GO:0030554;adenyl nucleotide binding;1.45541513731529e-22!GO:0009719;response to endogenous stimulus;1.49342438897003e-22!GO:0044455;mitochondrial membrane part;2.47999832489637e-22!GO:0006915;apoptosis;5.91026648109004e-22!GO:0006119;oxidative phosphorylation;5.98303002732023e-22!GO:0012501;programmed cell death;7.22086741864743e-22!GO:0015935;small ribosomal subunit;3.62854527383814e-21!GO:0006260;DNA replication;4.38530558620233e-21!GO:0006512;ubiquitin cycle;6.34015714682153e-21!GO:0044265;cellular macromolecule catabolic process;7.86523257593425e-21!GO:0022618;protein-RNA complex assembly;8.91816595139185e-21!GO:0015934;large ribosomal subunit;1.21578686304434e-20!GO:0016874;ligase activity;1.21578686304434e-20!GO:0008134;transcription factor binding;2.02490728944356e-20!GO:0042254;ribosome biogenesis and assembly;7.34366759319134e-20!GO:0005635;nuclear envelope;4.08334720613619e-19!GO:0008219;cell death;5.3034847923583e-19!GO:0016265;death;5.3034847923583e-19!GO:0043285;biopolymer catabolic process;2.835143088012e-18!GO:0016604;nuclear body;3.04869580510232e-18!GO:0000502;proteasome complex (sensu Eukaryota);4.1482557732962e-18!GO:0000398;nuclear mRNA splicing, via spliceosome;1.02619392896623e-17!GO:0000375;RNA splicing, via transesterification reactions;1.02619392896623e-17!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.02619392896623e-17!GO:0019941;modification-dependent protein catabolic process;1.21506260423597e-17!GO:0043632;modification-dependent macromolecule catabolic process;1.21506260423597e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;1.58510443118501e-17!GO:0031965;nuclear membrane;1.88047225053796e-17!GO:0016887;ATPase activity;2.12879727182981e-17!GO:0005746;mitochondrial respiratory chain;2.48688637402308e-17!GO:0012505;endomembrane system;2.72264269964374e-17!GO:0006511;ubiquitin-dependent protein catabolic process;2.88677138321222e-17!GO:0009057;macromolecule catabolic process;3.2551674137932e-17!GO:0006457;protein folding;4.08106903955681e-17!GO:0044257;cellular protein catabolic process;5.41030222777927e-17!GO:0042623;ATPase activity, coupled;7.24051565094902e-17!GO:0006325;establishment and/or maintenance of chromatin architecture;1.02710537748183e-16!GO:0005761;mitochondrial ribosome;1.31696819611907e-16!GO:0000313;organellar ribosome;1.31696819611907e-16!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;2.04914731780832e-16!GO:0008135;translation factor activity, nucleic acid binding;2.67507779378932e-16!GO:0006323;DNA packaging;2.76556272577258e-16!GO:0043412;biopolymer modification;5.42110296829756e-16!GO:0004386;helicase activity;5.59895194345108e-16!GO:0006605;protein targeting;7.0232591526625e-16!GO:0044248;cellular catabolic process;8.53278504734905e-16!GO:0050136;NADH dehydrogenase (quinone) activity;1.14714103817394e-15!GO:0003954;NADH dehydrogenase activity;1.14714103817394e-15!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.14714103817394e-15!GO:0044453;nuclear membrane part;1.56362770250338e-15!GO:0051726;regulation of cell cycle;4.03075989528356e-15!GO:0000074;regulation of progression through cell cycle;6.19024445343064e-15!GO:0006913;nucleocytoplasmic transport;1.05360314882975e-14!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);2.19902062082254e-14!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);2.28038344591914e-14!GO:0051169;nuclear transport;2.69211673251985e-14!GO:0042775;organelle ATP synthesis coupled electron transport;3.79796317123943e-14!GO:0042773;ATP synthesis coupled electron transport;3.79796317123943e-14!GO:0051186;cofactor metabolic process;3.87471224270971e-14!GO:0005643;nuclear pore;4.41857687356103e-14!GO:0003712;transcription cofactor activity;4.62418583916078e-14!GO:0042981;regulation of apoptosis;5.21662014109805e-14!GO:0050794;regulation of cellular process;5.36931697111334e-14!GO:0050657;nucleic acid transport;6.95165595539314e-14!GO:0051236;establishment of RNA localization;6.95165595539314e-14!GO:0050658;RNA transport;6.95165595539314e-14!GO:0006403;RNA localization;8.15556747743376e-14!GO:0006364;rRNA processing;8.92992233549725e-14!GO:0016607;nuclear speck;1.03452731627133e-13!GO:0043067;regulation of programmed cell death;1.0995828889706e-13!GO:0006464;protein modification process;1.21387436375762e-13!GO:0030964;NADH dehydrogenase complex (quinone);1.21675194549279e-13!GO:0045271;respiratory chain complex I;1.21675194549279e-13!GO:0005747;mitochondrial respiratory chain complex I;1.21675194549279e-13!GO:0006399;tRNA metabolic process;1.67620134153066e-13!GO:0016072;rRNA metabolic process;2.160826561037e-13!GO:0043687;post-translational protein modification;2.25679448769031e-13!GO:0000785;chromatin;2.63234202567301e-13!GO:0030163;protein catabolic process;2.82038742447606e-13!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;3.57711064580781e-13!GO:0008026;ATP-dependent helicase activity;4.36393100112135e-13!GO:0065002;intracellular protein transport across a membrane;6.50798129115133e-13!GO:0006333;chromatin assembly or disassembly;1.25920560230829e-12!GO:0006413;translational initiation;2.77309160786406e-12!GO:0003743;translation initiation factor activity;3.62358457611793e-12!GO:0051028;mRNA transport;4.85984774392133e-12!GO:0006732;coenzyme metabolic process;1.05607541526244e-11!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.06558298628232e-11!GO:0006446;regulation of translational initiation;1.16292192780905e-11!GO:0048770;pigment granule;1.24109194950495e-11!GO:0042470;melanosome;1.24109194950495e-11!GO:0046930;pore complex;1.323311517844e-11!GO:0006261;DNA-dependent DNA replication;1.70975001495842e-11!GO:0003697;single-stranded DNA binding;2.24162610147551e-11!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;2.71946272635908e-11!GO:0048193;Golgi vesicle transport;2.71946272635908e-11!GO:0016568;chromatin modification;3.01382817388997e-11!GO:0065004;protein-DNA complex assembly;3.07911841836752e-11!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;4.14429966658398e-11!GO:0051082;unfolded protein binding;4.24801587355046e-11!GO:0016779;nucleotidyltransferase activity;4.76142774375464e-11!GO:0043566;structure-specific DNA binding;5.70597487688706e-11!GO:0019222;regulation of metabolic process;6.4790132462427e-11!GO:0000775;chromosome, pericentric region;7.76908572807305e-11!GO:0005783;endoplasmic reticulum;9.02991225248283e-11!GO:0006366;transcription from RNA polymerase II promoter;1.01945725669966e-10!GO:0009055;electron carrier activity;2.66508813359085e-10!GO:0051246;regulation of protein metabolic process;2.71814205555099e-10!GO:0017038;protein import;2.95528945463651e-10!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;3.24955481079018e-10!GO:0004812;aminoacyl-tRNA ligase activity;3.24955481079018e-10!GO:0016875;ligase activity, forming carbon-oxygen bonds;3.24955481079018e-10!GO:0030532;small nuclear ribonucleoprotein complex;3.31530269484009e-10!GO:0044432;endoplasmic reticulum part;3.32160998695683e-10!GO:0008639;small protein conjugating enzyme activity;4.04325280758915e-10!GO:0043038;amino acid activation;5.79003372975643e-10!GO:0006418;tRNA aminoacylation for protein translation;5.79003372975643e-10!GO:0043039;tRNA aminoacylation;5.79003372975643e-10!GO:0004842;ubiquitin-protein ligase activity;7.33153379853625e-10!GO:0019787;small conjugating protein ligase activity;1.1132420702284e-09!GO:0009259;ribonucleotide metabolic process;1.26835986689458e-09!GO:0005819;spindle;1.63332133161481e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;2.29856397027121e-09!GO:0006163;purine nucleotide metabolic process;2.58199094042291e-09!GO:0006461;protein complex assembly;3.13815719291562e-09!GO:0009615;response to virus;4.20650146845499e-09!GO:0003713;transcription coactivator activity;4.30531777910712e-09!GO:0006164;purine nucleotide biosynthetic process;5.02192342622225e-09!GO:0031323;regulation of cellular metabolic process;5.56579589297074e-09!GO:0009260;ribonucleotide biosynthetic process;6.03166861926384e-09!GO:0016740;transferase activity;6.63357668535894e-09!GO:0016563;transcription activator activity;7.44501658989252e-09!GO:0009056;catabolic process;7.9267028647913e-09!GO:0007249;I-kappaB kinase/NF-kappaB cascade;8.47038766757394e-09!GO:0007005;mitochondrion organization and biogenesis;8.69927243566103e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;8.96488214403504e-09!GO:0008094;DNA-dependent ATPase activity;1.01751737283799e-08!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;1.0688149416135e-08!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.93112262780148e-08!GO:0051188;cofactor biosynthetic process;1.98392679139197e-08!GO:0005839;proteasome core complex (sensu Eukaryota);2.05094471000632e-08!GO:0009150;purine ribonucleotide metabolic process;2.05094471000632e-08!GO:0050789;regulation of biological process;2.28798373874495e-08!GO:0008565;protein transporter activity;2.42674492561589e-08!GO:0015630;microtubule cytoskeleton;2.43967981706329e-08!GO:0006793;phosphorus metabolic process;2.45478996517354e-08!GO:0006796;phosphate metabolic process;2.45478996517354e-08!GO:0005789;endoplasmic reticulum membrane;2.75233223534379e-08!GO:0009060;aerobic respiration;2.7853947128234e-08!GO:0016787;hydrolase activity;3.56018113100627e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;3.57955051075418e-08!GO:0009152;purine ribonucleotide biosynthetic process;3.97344410927529e-08!GO:0006310;DNA recombination;4.00017200887462e-08!GO:0000245;spliceosome assembly;4.13219061734634e-08!GO:0005813;centrosome;4.26864684538743e-08!GO:0016881;acid-amino acid ligase activity;4.27669068242694e-08!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;4.30093730292694e-08!GO:0007051;spindle organization and biogenesis;5.42108596675641e-08!GO:0000075;cell cycle checkpoint;5.83334294077899e-08!GO:0005794;Golgi apparatus;7.55976034038634e-08!GO:0015078;hydrogen ion transmembrane transporter activity;8.38271957611537e-08!GO:0005657;replication fork;8.77563919605502e-08!GO:0005815;microtubule organizing center;8.98422987302169e-08!GO:0045333;cellular respiration;9.5929788979986e-08!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.00460535677091e-07!GO:0006350;transcription;1.01651779621745e-07!GO:0007059;chromosome segregation;1.08413479800458e-07!GO:0006916;anti-apoptosis;1.1235581025917e-07!GO:0019829;cation-transporting ATPase activity;1.35237402307359e-07!GO:0004298;threonine endopeptidase activity;1.41301456257263e-07!GO:0043069;negative regulation of programmed cell death;1.94000627734812e-07!GO:0006334;nucleosome assembly;2.17477463124468e-07!GO:0043066;negative regulation of apoptosis;2.27397415810564e-07!GO:0006099;tricarboxylic acid cycle;2.55812704888534e-07!GO:0046356;acetyl-CoA catabolic process;2.55812704888534e-07!GO:0009108;coenzyme biosynthetic process;2.56590070511057e-07!GO:0051168;nuclear export;2.56590070511057e-07!GO:0015986;ATP synthesis coupled proton transport;2.73554825517358e-07!GO:0015985;energy coupled proton transport, down electrochemical gradient;2.73554825517358e-07!GO:0006401;RNA catabolic process;3.03049169444903e-07!GO:0031202;RNA splicing factor activity, transesterification mechanism;3.06998098703728e-07!GO:0031497;chromatin assembly;3.33689662396293e-07!GO:0051170;nuclear import;3.37837258223659e-07!GO:0016310;phosphorylation;3.73233732438114e-07!GO:0045259;proton-transporting ATP synthase complex;4.55051612774911e-07!GO:0051325;interphase;4.57065039893199e-07!GO:0006888;ER to Golgi vesicle-mediated transport;4.58321786305524e-07!GO:0032446;protein modification by small protein conjugation;4.97279896663351e-07!GO:0003899;DNA-directed RNA polymerase activity;5.83242547806081e-07!GO:0006084;acetyl-CoA metabolic process;5.84232496759793e-07!GO:0051329;interphase of mitotic cell cycle;6.04112485158821e-07!GO:0043065;positive regulation of apoptosis;7.19057034761787e-07!GO:0006606;protein import into nucleus;7.26950742176231e-07!GO:0006302;double-strand break repair;7.61125611125491e-07!GO:0016772;transferase activity, transferring phosphorus-containing groups;7.81950976187261e-07!GO:0010468;regulation of gene expression;8.09713242876723e-07!GO:0003724;RNA helicase activity;8.55750981834542e-07!GO:0016192;vesicle-mediated transport;9.20140413679178e-07!GO:0007088;regulation of mitosis;9.819442338585e-07!GO:0016567;protein ubiquitination;1.06870211750035e-06!GO:0030120;vesicle coat;1.08880047067563e-06!GO:0030662;coated vesicle membrane;1.08880047067563e-06!GO:0048523;negative regulation of cellular process;1.12055909903543e-06!GO:0043068;positive regulation of programmed cell death;1.15861703042445e-06!GO:0016363;nuclear matrix;1.41664395529684e-06!GO:0009142;nucleoside triphosphate biosynthetic process;1.62618160475035e-06!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.62618160475035e-06!GO:0051187;cofactor catabolic process;1.64024848656968e-06!GO:0009199;ribonucleoside triphosphate metabolic process;1.83762815939496e-06!GO:0019899;enzyme binding;1.90899982372138e-06!GO:0009117;nucleotide metabolic process;1.95139188743224e-06!GO:0009141;nucleoside triphosphate metabolic process;1.95382963073598e-06!GO:0048475;coated membrane;2.17734076826857e-06!GO:0030117;membrane coat;2.17734076826857e-06!GO:0006754;ATP biosynthetic process;2.29562561096331e-06!GO:0006753;nucleoside phosphate metabolic process;2.29562561096331e-06!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.32101699658679e-06!GO:0006917;induction of apoptosis;2.7052489671889e-06!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;3.26699309785069e-06!GO:0009145;purine nucleoside triphosphate biosynthetic process;3.26699309785069e-06!GO:0009205;purine ribonucleoside triphosphate metabolic process;3.53464521579397e-06!GO:0009144;purine nucleoside triphosphate metabolic process;3.53464521579397e-06!GO:0005768;endosome;3.6211899439999e-06!GO:0046034;ATP metabolic process;3.71785449372222e-06!GO:0006402;mRNA catabolic process;3.71785449372222e-06!GO:0009109;coenzyme catabolic process;3.94445397164373e-06!GO:0000776;kinetochore;4.22126547931978e-06!GO:0012502;induction of programmed cell death;4.31843626979354e-06!GO:0016469;proton-transporting two-sector ATPase complex;4.46664838088788e-06!GO:0007243;protein kinase cascade;4.8374443817398e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;5.50134665110486e-06!GO:0044452;nucleolar part;5.51538818024383e-06!GO:0006417;regulation of translation;5.71480671891662e-06!GO:0051052;regulation of DNA metabolic process;7.68972007411574e-06!GO:0005793;ER-Golgi intermediate compartment;7.74230486113436e-06!GO:0006752;group transfer coenzyme metabolic process;7.91812698682123e-06!GO:0043623;cellular protein complex assembly;9.77583739631702e-06!GO:0006613;cotranslational protein targeting to membrane;1.06092283940846e-05!GO:0005667;transcription factor complex;1.28515368707123e-05!GO:0000314;organellar small ribosomal subunit;1.3741922375965e-05!GO:0005763;mitochondrial small ribosomal subunit;1.3741922375965e-05!GO:0004527;exonuclease activity;1.38984051531249e-05!GO:0051427;hormone receptor binding;1.41805767564765e-05!GO:0016741;transferase activity, transferring one-carbon groups;1.55762177053938e-05!GO:0045786;negative regulation of progression through cell cycle;1.62445603695642e-05!GO:0000151;ubiquitin ligase complex;1.70307013796106e-05!GO:0005762;mitochondrial large ribosomal subunit;1.77066569956463e-05!GO:0000315;organellar large ribosomal subunit;1.77066569956463e-05!GO:0005770;late endosome;1.81427485759042e-05!GO:0048522;positive regulation of cellular process;1.88392818856883e-05!GO:0006839;mitochondrial transport;2.10355459820186e-05!GO:0005525;GTP binding;2.40585783945267e-05!GO:0003677;DNA binding;2.59963315614653e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;2.62629736387246e-05!GO:0003678;DNA helicase activity;2.62650968624579e-05!GO:0007093;mitotic cell cycle checkpoint;2.65211349797521e-05!GO:0008168;methyltransferase activity;2.70688061569813e-05!GO:0003684;damaged DNA binding;2.72499531300044e-05!GO:0048519;negative regulation of biological process;2.83350467301911e-05!GO:0032774;RNA biosynthetic process;2.88358115592203e-05!GO:0035257;nuclear hormone receptor binding;3.00092270659382e-05!GO:0003690;double-stranded DNA binding;3.4179156374288e-05!GO:0043021;ribonucleoprotein binding;3.56852940287435e-05!GO:0004518;nuclease activity;3.59776976436303e-05!GO:0016564;transcription repressor activity;3.77640699683391e-05!GO:0006351;transcription, DNA-dependent;3.80697583385163e-05!GO:0051252;regulation of RNA metabolic process;3.82770455835118e-05!GO:0003924;GTPase activity;4.87298662970106e-05!GO:0005798;Golgi-associated vesicle;4.88040627225631e-05!GO:0008033;tRNA processing;5.54694144426182e-05!GO:0008186;RNA-dependent ATPase activity;5.56357137646435e-05!GO:0009165;nucleotide biosynthetic process;5.58413468402665e-05!GO:0003682;chromatin binding;6.70242549965915e-05!GO:0003729;mRNA binding;7.58574797574343e-05!GO:0031324;negative regulation of cellular metabolic process;7.80886283849178e-05!GO:0031326;regulation of cellular biosynthetic process;7.89445454150196e-05!GO:0003714;transcription corepressor activity;8.37302946652292e-05!GO:0000786;nucleosome;0.000106167006140633!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.00011640494292388!GO:0006950;response to stress;0.000129753405256157!GO:0045449;regulation of transcription;0.000132665373806471!GO:0043681;protein import into mitochondrion;0.000134719042393203!GO:0006383;transcription from RNA polymerase III promoter;0.000135824094231808!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000136767534848213!GO:0030880;RNA polymerase complex;0.000137422269041605!GO:0006352;transcription initiation;0.000137984147110328!GO:0016251;general RNA polymerase II transcription factor activity;0.000139660060886653!GO:0065007;biological regulation;0.000140250354669735!GO:0006626;protein targeting to mitochondrion;0.00015211991231988!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000155858855763543!GO:0004004;ATP-dependent RNA helicase activity;0.000171722640129378!GO:0007006;mitochondrial membrane organization and biogenesis;0.000176127417743423!GO:0044440;endosomal part;0.000178955591069254!GO:0010008;endosome membrane;0.000178955591069254!GO:0005048;signal sequence binding;0.000216033189583225!GO:0007052;mitotic spindle organization and biogenesis;0.000219656106226104!GO:0032561;guanyl ribonucleotide binding;0.000219876628620433!GO:0019001;guanyl nucleotide binding;0.000219876628620433!GO:0005885;Arp2/3 protein complex;0.000225734353663039!GO:0030658;transport vesicle membrane;0.000266168653745725!GO:0042770;DNA damage response, signal transduction;0.000266168653745725!GO:0048471;perinuclear region of cytoplasm;0.000270540666119715!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.00027480028863166!GO:0015399;primary active transmembrane transporter activity;0.00027480028863166!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000292774855831712!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.000299348394637186!GO:0000428;DNA-directed RNA polymerase complex;0.000299348394637186!GO:0007010;cytoskeleton organization and biogenesis;0.000301269402996363!GO:0031072;heat shock protein binding;0.000320278258655377!GO:0043488;regulation of mRNA stability;0.000321918438751577!GO:0043487;regulation of RNA stability;0.000321918438751577!GO:0006414;translational elongation;0.000338660350722536!GO:0032508;DNA duplex unwinding;0.000343505543192553!GO:0032392;DNA geometric change;0.000343505543192553!GO:0005684;U2-dependent spliceosome;0.000348657146472806!GO:0008632;apoptotic program;0.000365316139640338!GO:0006612;protein targeting to membrane;0.000375759181294148!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000383037553293878!GO:0065009;regulation of a molecular function;0.00040406598858809!GO:0016853;isomerase activity;0.000419967973617208!GO:0006611;protein export from nucleus;0.000425696283845108!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000428058063970205!GO:0000228;nuclear chromosome;0.000429112283075856!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.000444113543351773!GO:0000819;sister chromatid segregation;0.000458601154757569!GO:0005741;mitochondrial outer membrane;0.000503460534980839!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000513564423777688!GO:0003725;double-stranded RNA binding;0.000541206922204925!GO:0031968;organelle outer membrane;0.000555865634741601!GO:0000070;mitotic sister chromatid segregation;0.00057856445139232!GO:0004674;protein serine/threonine kinase activity;0.000609788492558272!GO:0006268;DNA unwinding during replication;0.000633468870175177!GO:0032200;telomere organization and biogenesis;0.000633468870175177!GO:0000723;telomere maintenance;0.000633468870175177!GO:0019867;outer membrane;0.000669882047796126!GO:0000082;G1/S transition of mitotic cell cycle;0.000687762354761833!GO:0030660;Golgi-associated vesicle membrane;0.000687762354761833!GO:0009889;regulation of biosynthetic process;0.000703702149227532!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000754366648703524!GO:0006270;DNA replication initiation;0.000759222346211205!GO:0031970;organelle envelope lumen;0.000759222346211205!GO:0046483;heterocycle metabolic process;0.000766201190313558!GO:0006405;RNA export from nucleus;0.000789412688814793!GO:0016281;eukaryotic translation initiation factor 4F complex;0.000835426589096369!GO:0044431;Golgi apparatus part;0.000897283229759444!GO:0043596;nuclear replication fork;0.000908528427135665!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.000908528427135665!GO:0048500;signal recognition particle;0.000915494887881139!GO:0000059;protein import into nucleus, docking;0.000999791470604865!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00101467999885762!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00101467999885762!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00101467999885762!GO:0009892;negative regulation of metabolic process;0.00107117650296367!GO:0005758;mitochondrial intermembrane space;0.00107814196789608!GO:0000725;recombinational repair;0.00108647813416049!GO:0000724;double-strand break repair via homologous recombination;0.00108647813416049!GO:0004532;exoribonuclease activity;0.00108647813416049!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00108647813416049!GO:0005876;spindle microtubule;0.00116503603684422!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00116503603684422!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00116503603684422!GO:0008139;nuclear localization sequence binding;0.00122816314802861!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00131455091227702!GO:0000922;spindle pole;0.00132975783280564!GO:0004003;ATP-dependent DNA helicase activity;0.00133681110955621!GO:0006891;intra-Golgi vesicle-mediated transport;0.00139424481178877!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.00146538688838152!GO:0048518;positive regulation of biological process;0.00152628269599703!GO:0006818;hydrogen transport;0.00157828346371434!GO:0016859;cis-trans isomerase activity;0.00167451385429859!GO:0005637;nuclear inner membrane;0.00169389352780124!GO:0008408;3'-5' exonuclease activity;0.00170401705410314!GO:0035258;steroid hormone receptor binding;0.00174217374877265!GO:0009967;positive regulation of signal transduction;0.00174407802090663!GO:0015992;proton transport;0.00177663996631136!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00178567501024876!GO:0016481;negative regulation of transcription;0.00180783127909391!GO:0000049;tRNA binding;0.00181132351251074!GO:0003711;transcription elongation regulator activity;0.00186769604580276!GO:0031124;mRNA 3'-end processing;0.00190783633752253!GO:0005769;early endosome;0.00191018188821694!GO:0045454;cell redox homeostasis;0.00191319970436626!GO:0009451;RNA modification;0.00198344526662829!GO:0008312;7S RNA binding;0.00198385249552821!GO:0006091;generation of precursor metabolites and energy;0.00203588026415486!GO:0006520;amino acid metabolic process;0.00206400746312612!GO:0007017;microtubule-based process;0.00211678415060045!GO:0006355;regulation of transcription, DNA-dependent;0.00216966912856591!GO:0047485;protein N-terminus binding;0.00224828504403511!GO:0006338;chromatin remodeling;0.00231685275971014!GO:0051920;peroxiredoxin activity;0.00231685275971014!GO:0022890;inorganic cation transmembrane transporter activity;0.00238591120856304!GO:0016491;oxidoreductase activity;0.00238718315101084!GO:0006289;nucleotide-excision repair;0.00246504873326481!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00247821062980229!GO:0030521;androgen receptor signaling pathway;0.00251367451630663!GO:0006595;polyamine metabolic process;0.0025992739453474!GO:0033673;negative regulation of kinase activity;0.00268258390322995!GO:0006469;negative regulation of protein kinase activity;0.00268258390322995!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0027404019430065!GO:0045047;protein targeting to ER;0.0027404019430065!GO:0000793;condensed chromosome;0.00279780426105402!GO:0046822;regulation of nucleocytoplasmic transport;0.00284143273229273!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00285178204090395!GO:0045941;positive regulation of transcription;0.00295448797697068!GO:0003702;RNA polymerase II transcription factor activity;0.00298250738498515!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0030379229127637!GO:0009124;nucleoside monophosphate biosynthetic process;0.0030379229127637!GO:0009123;nucleoside monophosphate metabolic process;0.0030379229127637!GO:0051348;negative regulation of transferase activity;0.00304663890590939!GO:0000781;chromosome, telomeric region;0.00315816073810772!GO:0043492;ATPase activity, coupled to movement of substances;0.00318367106134758!GO:0030518;steroid hormone receptor signaling pathway;0.00330662332510311!GO:0051539;4 iron, 4 sulfur cluster binding;0.00334036257336206!GO:0016791;phosphoric monoester hydrolase activity;0.00334068618996457!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00334068618996457!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00334068618996457!GO:0000323;lytic vacuole;0.00334277248183527!GO:0005764;lysosome;0.00334277248183527!GO:0009112;nucleobase metabolic process;0.00336807045564444!GO:0016126;sterol biosynthetic process;0.00344446053697109!GO:0006284;base-excision repair;0.00346043829799274!GO:0051223;regulation of protein transport;0.0035363208641366!GO:0042393;histone binding;0.00357212502132781!GO:0008234;cysteine-type peptidase activity;0.00364139740831103!GO:0006275;regulation of DNA replication;0.00370250391382484!GO:0030134;ER to Golgi transport vesicle;0.00371900254681025!GO:0030867;rough endoplasmic reticulum membrane;0.00383410989836421!GO:0016584;nucleosome positioning;0.00387461854801161!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00395191662597768!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00395191662597768!GO:0015002;heme-copper terminal oxidase activity;0.00395191662597768!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00395191662597768!GO:0004129;cytochrome-c oxidase activity;0.00395191662597768!GO:0032259;methylation;0.00397309779706062!GO:0000178;exosome (RNase complex);0.00407769938713356!GO:0048468;cell development;0.00408331922375167!GO:0030127;COPII vesicle coat;0.00415098489842435!GO:0012507;ER to Golgi transport vesicle membrane;0.00415098489842435!GO:0043601;nuclear replisome;0.00427840390713836!GO:0030894;replisome;0.00427840390713836!GO:0019752;carboxylic acid metabolic process;0.00435810864075347!GO:0006144;purine base metabolic process;0.00439766864849514!GO:0008654;phospholipid biosynthetic process;0.00449090060955873!GO:0000339;RNA cap binding;0.00453406109086344!GO:0005773;vacuole;0.00454683514523495!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.0046644775878293!GO:0051092;activation of NF-kappaB transcription factor;0.00522017268177653!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00527657954059682!GO:0006082;organic acid metabolic process;0.00529598981724678!GO:0031123;RNA 3'-end processing;0.00534731715030852!GO:0003887;DNA-directed DNA polymerase activity;0.00537958753122167!GO:0008022;protein C-terminus binding;0.00539827159598518!GO:0015631;tubulin binding;0.00552240254458752!GO:0031570;DNA integrity checkpoint;0.00552374824302531!GO:0042802;identical protein binding;0.00552374824302531!GO:0016197;endosome transport;0.00568858197306491!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00580641504453039!GO:0009116;nucleoside metabolic process;0.005835034418723!GO:0031252;leading edge;0.00591358453956089!GO:0051053;negative regulation of DNA metabolic process;0.00595416786075678!GO:0046966;thyroid hormone receptor binding;0.00600992242743494!GO:0030384;phosphoinositide metabolic process;0.00605395061388812!GO:0022411;cellular component disassembly;0.00606068483216634!GO:0000152;nuclear ubiquitin ligase complex;0.00629319932971199!GO:0051789;response to protein stimulus;0.00629774698862857!GO:0006986;response to unfolded protein;0.00629774698862857!GO:0000175;3'-5'-exoribonuclease activity;0.00636428285241742!GO:0008629;induction of apoptosis by intracellular signals;0.00639586452003908!GO:0005669;transcription factor TFIID complex;0.00661119528324962!GO:0030118;clathrin coat;0.00672889478636936!GO:0006007;glucose catabolic process;0.00674040645450447!GO:0006695;cholesterol biosynthetic process;0.00675670387604886!GO:0051087;chaperone binding;0.00697502073772472!GO:0009161;ribonucleoside monophosphate metabolic process;0.00700750977854496!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.00700750977854496!GO:0043022;ribosome binding;0.00709473452367244!GO:0044450;microtubule organizing center part;0.00709473452367244!GO:0006376;mRNA splice site selection;0.00719015572123318!GO:0000389;nuclear mRNA 3'-splice site recognition;0.00719015572123318!GO:0018193;peptidyl-amino acid modification;0.00760258067593352!GO:0045893;positive regulation of transcription, DNA-dependent;0.00760258067593352!GO:0030133;transport vesicle;0.00764610762638741!GO:0030036;actin cytoskeleton organization and biogenesis;0.00773173633148044!GO:0022415;viral reproductive process;0.00790221401166314!GO:0000209;protein polyubiquitination;0.00797963413403358!GO:0005663;DNA replication factor C complex;0.0082678752511054!GO:0044454;nuclear chromosome part;0.00833113704597048!GO:0007242;intracellular signaling cascade;0.00841260695659288!GO:0003746;translation elongation factor activity;0.00872587835943069!GO:0016272;prefoldin complex;0.00882281442559895!GO:0000139;Golgi membrane;0.00909946979019984!GO:0005832;chaperonin-containing T-complex;0.00922269123885196!GO:0051540;metal cluster binding;0.00939019617654382!GO:0051536;iron-sulfur cluster binding;0.00939019617654382!GO:0051098;regulation of binding;0.00956403764243309!GO:0008624;induction of apoptosis by extracellular signals;0.00964984422570051!GO:0030663;COPI coated vesicle membrane;0.00967985255119101!GO:0030126;COPI vesicle coat;0.00967985255119101!GO:0008637;apoptotic mitochondrial changes;0.00978970811648208!GO:0008047;enzyme activator activity;0.00999020729209664!GO:0043414;biopolymer methylation;0.0103731115250815!GO:0009303;rRNA transcription;0.0104617350803933!GO:0008276;protein methyltransferase activity;0.0104617350803933!GO:0051656;establishment of organelle localization;0.0109953836319103!GO:0042613;MHC class II protein complex;0.0110265700196345!GO:0007004;telomere maintenance via telomerase;0.0112300244953229!GO:0032984;macromolecular complex disassembly;0.0114803883326231!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0118408872302858!GO:0006400;tRNA modification;0.0120612688779591!GO:0031902;late endosome membrane;0.01209578426596!GO:0006650;glycerophospholipid metabolic process;0.0121846454262946!GO:0005788;endoplasmic reticulum lumen;0.0122312756136321!GO:0009893;positive regulation of metabolic process;0.0123192134360244!GO:0000726;non-recombinational repair;0.0123192134360244!GO:0031577;spindle checkpoint;0.0126565896503876!GO:0006378;mRNA polyadenylation;0.012730040075937!GO:0000910;cytokinesis;0.0127380743546603!GO:0007264;small GTPase mediated signal transduction;0.0127931677057816!GO:0015980;energy derivation by oxidation of organic compounds;0.0132670396517844!GO:0001824;blastocyst development;0.0134718668388202!GO:0005874;microtubule;0.0134718668388202!GO:0051090;regulation of transcription factor activity;0.0135372369258662!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0135379144133489!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0135500451941283!GO:0007050;cell cycle arrest;0.0139919722898653!GO:0046112;nucleobase biosynthetic process;0.0139919722898653!GO:0019843;rRNA binding;0.014345434646846!GO:0031625;ubiquitin protein ligase binding;0.0143598215227044!GO:0000288;mRNA catabolic process, deadenylation-dependent decay;0.014378810953518!GO:0004721;phosphoprotein phosphatase activity;0.0143953726929906!GO:0016788;hydrolase activity, acting on ester bonds;0.0144210242346764!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.0145861250328779!GO:0043624;cellular protein complex disassembly;0.014975157124528!GO:0030137;COPI-coated vesicle;0.0150976041093631!GO:0051101;regulation of DNA binding;0.0154460503135135!GO:0050662;coenzyme binding;0.0154700809786335!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0157965453635336!GO:0046489;phosphoinositide biosynthetic process;0.0158346293491253!GO:0004576;oligosaccharyl transferase activity;0.0158346293491253!GO:0033367;protein localization in mast cell secretory granule;0.0158346293491253!GO:0033365;protein localization in organelle;0.0158346293491253!GO:0033371;T cell secretory granule organization and biogenesis;0.0158346293491253!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.0158346293491253!GO:0033375;protease localization in T cell secretory granule;0.0158346293491253!GO:0042629;mast cell granule;0.0158346293491253!GO:0033377;maintenance of protein localization in T cell secretory granule;0.0158346293491253!GO:0033364;mast cell secretory granule organization and biogenesis;0.0158346293491253!GO:0033380;granzyme B localization in T cell secretory granule;0.0158346293491253!GO:0033379;maintenance of protease localization in T cell secretory granule;0.0158346293491253!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.0158346293491253!GO:0033368;protease localization in mast cell secretory granule;0.0158346293491253!GO:0033366;protein localization in secretory granule;0.0158346293491253!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.0158346293491253!GO:0033374;protein localization in T cell secretory granule;0.0158346293491253!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0159407918823015!GO:0008250;oligosaccharyl transferase complex;0.0159407918823015!GO:0031325;positive regulation of cellular metabolic process;0.0163023135603409!GO:0045045;secretory pathway;0.0163643854422472!GO:0000077;DNA damage checkpoint;0.0165459140139329!GO:0043241;protein complex disassembly;0.0170127416587281!GO:0033116;ER-Golgi intermediate compartment membrane;0.0170619456412538!GO:0006278;RNA-dependent DNA replication;0.0178033287388483!GO:0042113;B cell activation;0.0178176903467188!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.0192200086999396!GO:0000118;histone deacetylase complex;0.0192258797207641!GO:0008538;proteasome activator activity;0.019263885727834!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0199846194874558!GO:0019904;protein domain specific binding;0.0201374511467896!GO:0008180;signalosome;0.0202355706402153!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0206350920085289!GO:0004540;ribonuclease activity;0.0206765986449415!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.0212180083006396!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.0212180083006396!GO:0009126;purine nucleoside monophosphate metabolic process;0.0212180083006396!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.0212180083006396!GO:0000287;magnesium ion binding;0.0215690270273115!GO:0005791;rough endoplasmic reticulum;0.0219934866000721!GO:0044438;microbody part;0.0219936508007294!GO:0044439;peroxisomal part;0.0219936508007294!GO:0000792;heterochromatin;0.0224065893284933!GO:0032940;secretion by cell;0.0224613514520546!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0225264478111731!GO:0043621;protein self-association;0.0228081268598022!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0229034909985857!GO:0000018;regulation of DNA recombination;0.0232021600125019!GO:0008156;negative regulation of DNA replication;0.0233309709069998!GO:0046649;lymphocyte activation;0.0234025203772316!GO:0000738;DNA catabolic process, exonucleolytic;0.0234690866192628!GO:0006096;glycolysis;0.0234690866192628!GO:0000119;mediator complex;0.0235731825739798!GO:0019783;small conjugating protein-specific protease activity;0.0235796010405854!GO:0007265;Ras protein signal transduction;0.0238734913543987!GO:0050681;androgen receptor binding;0.0248655166613217!GO:0016311;dephosphorylation;0.0250249618805888!GO:0006519;amino acid and derivative metabolic process;0.0257660103041944!GO:0006596;polyamine biosynthetic process;0.0259023421154834!GO:0016407;acetyltransferase activity;0.026105312196715!GO:0032404;mismatch repair complex binding;0.026350825737812!GO:0005732;small nucleolar ribonucleoprotein complex;0.0264267848064189!GO:0050790;regulation of catalytic activity;0.0264267848064189!GO:0008287;protein serine/threonine phosphatase complex;0.0269706885263707!GO:0004536;deoxyribonuclease activity;0.0269706885263707!GO:0030029;actin filament-based process;0.0269706885263707!GO:0004843;ubiquitin-specific protease activity;0.0270420521270247!GO:0032039;integrator complex;0.027135925230881!GO:0030125;clathrin vesicle coat;0.0271627080289866!GO:0030665;clathrin coated vesicle membrane;0.0271627080289866!GO:0048487;beta-tubulin binding;0.0271627080289866!GO:0005096;GTPase activator activity;0.0271885084122467!GO:0046365;monosaccharide catabolic process;0.0279645305079841!GO:0030433;ER-associated protein catabolic process;0.0281802997477384!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0281802997477384!GO:0004177;aminopeptidase activity;0.0281887597182533!GO:0045892;negative regulation of transcription, DNA-dependent;0.0285121087547771!GO:0006406;mRNA export from nucleus;0.028560279559151!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0288602372891904!GO:0000096;sulfur amino acid metabolic process;0.0288677684241764!GO:0008270;zinc ion binding;0.028932041524537!GO:0007094;mitotic cell cycle spindle assembly checkpoint;0.0290034028774304!GO:0008097;5S rRNA binding;0.0290455673383938!GO:0033170;DNA-protein loading ATPase activity;0.0291516638336214!GO:0003689;DNA clamp loader activity;0.0291516638336214!GO:0051235;maintenance of localization;0.0297045005156508!GO:0004448;isocitrate dehydrogenase activity;0.0297045005156508!GO:0004748;ribonucleoside-diphosphate reductase activity;0.0297045005156508!GO:0016728;oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor;0.0297045005156508!GO:0006308;DNA catabolic process;0.0298868302866541!GO:0030695;GTPase regulator activity;0.0301262352974249!GO:0043284;biopolymer biosynthetic process;0.0301262352974249!GO:0046474;glycerophospholipid biosynthetic process;0.030170246074299!GO:0030140;trans-Golgi network transport vesicle;0.030170246074299!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0305455022966295!GO:0045039;protein import into mitochondrial inner membrane;0.0305455022966295!GO:0030522;intracellular receptor-mediated signaling pathway;0.0306983092765499!GO:0031371;ubiquitin conjugating enzyme complex;0.0309491153478328!GO:0046426;negative regulation of JAK-STAT cascade;0.0310446391043425!GO:0008320;protein transmembrane transporter activity;0.0313147304252641!GO:0005744;mitochondrial inner membrane presequence translocase complex;0.0315245528852999!GO:0031903;microbody membrane;0.0320380785157146!GO:0005778;peroxisomal membrane;0.0320380785157146!GO:0001891;phagocytic cup;0.0321322858453548!GO:0022884;macromolecule transmembrane transporter activity;0.0321643926521754!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0321643926521754!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0323108093445208!GO:0006730;one-carbon compound metabolic process;0.0323108093445208!GO:0035267;NuA4 histone acetyltransferase complex;0.0326108093712619!GO:0042532;negative regulation of tyrosine phosphorylation of STAT protein;0.0331984045646688!GO:0042518;negative regulation of tyrosine phosphorylation of Stat3 protein;0.0331984045646688!GO:0050732;negative regulation of peptidyl-tyrosine phosphorylation;0.0331984045646688!GO:0030262;apoptotic nuclear changes;0.0337284896104571!GO:0005092;GDP-dissociation inhibitor activity;0.034273921864148!GO:0032405;MutLalpha complex binding;0.0343023994746993!GO:0030508;thiol-disulfide exchange intermediate activity;0.0359476450984053!GO:0006354;RNA elongation;0.0363730753697752!GO:0016301;kinase activity;0.0366869430027685!GO:0008017;microtubule binding;0.0366869430027685!GO:0008537;proteasome activator complex;0.0370340503472128!GO:0051640;organelle localization;0.0371468426796301!GO:0016605;PML body;0.0374350029718109!GO:0031647;regulation of protein stability;0.0377005797237854!GO:0004722;protein serine/threonine phosphatase activity;0.0383146473899618!GO:0018196;peptidyl-asparagine modification;0.0383146473899618!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0383146473899618!GO:0051338;regulation of transferase activity;0.0383642624635585!GO:0005652;nuclear lamina;0.0386852151502244!GO:0004221;ubiquitin thiolesterase activity;0.0393298091158923!GO:0050851;antigen receptor-mediated signaling pathway;0.0393427143827839!GO:0042026;protein refolding;0.0401460613109438!GO:0005680;anaphase-promoting complex;0.0402925670416542!GO:0051297;centrosome organization and biogenesis;0.0405796950320109!GO:0031023;microtubule organizing center organization and biogenesis;0.0405796950320109!GO:0009081;branched chain family amino acid metabolic process;0.0407552978359656!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0407552978359656!GO:0001832;blastocyst growth;0.0407552978359656!GO:0050178;phenylpyruvate tautomerase activity;0.040830722821673!GO:0045815;positive regulation of gene expression, epigenetic;0.0413317694821335!GO:0005689;U12-dependent spliceosome;0.0413497854004686!GO:0043549;regulation of kinase activity;0.0413707504458702!GO:0006301;postreplication repair;0.0418936271346143!GO:0015036;disulfide oxidoreductase activity;0.0428229020627442!GO:0030176;integral to endoplasmic reticulum membrane;0.0429432644779458!GO:0046128;purine ribonucleoside metabolic process;0.043127003059082!GO:0042278;purine nucleoside metabolic process;0.043127003059082!GO:0019320;hexose catabolic process;0.0431981814108705!GO:0043130;ubiquitin binding;0.0431981814108705!GO:0032182;small conjugating protein binding;0.0431981814108705!GO:0008630;DNA damage response, signal transduction resulting in induction of apoptosis;0.0438441167177541!GO:0016790;thiolester hydrolase activity;0.0439683674517469!GO:0051881;regulation of mitochondrial membrane potential;0.0443620239615474!GO:0005869;dynactin complex;0.0445048400555758!GO:0004659;prenyltransferase activity;0.0446693553968028!GO:0006767;water-soluble vitamin metabolic process;0.0447033570070371!GO:0042054;histone methyltransferase activity;0.0448290318470107!GO:0007098;centrosome cycle;0.0448986026681786!GO:0006984;ER-nuclear signaling pathway;0.0451332915321562!GO:0046164;alcohol catabolic process;0.0456005194832156!GO:0006778;porphyrin metabolic process;0.0456005194832156!GO:0033013;tetrapyrrole metabolic process;0.0456005194832156!GO:0006607;NLS-bearing substrate import into nucleus;0.045611247659525!GO:0030119;AP-type membrane coat adaptor complex;0.0459117570440595!GO:0043189;H4/H2A histone acetyltransferase complex;0.046287339442631!GO:0031988;membrane-bound vesicle;0.0465349627820063!GO:0000123;histone acetyltransferase complex;0.0473112272284436!GO:0030261;chromosome condensation;0.047982934100661!GO:0000930;gamma-tubulin complex;0.0480911112951122!GO:0000086;G2/M transition of mitotic cell cycle;0.0482727573904138!GO:0030130;clathrin coat of trans-Golgi network vesicle;0.0482727573904138!GO:0012510;trans-Golgi network transport vesicle membrane;0.0482727573904138!GO:0043631;RNA polyadenylation;0.0487051544181587!GO:0005784;translocon complex;0.0488465639134826!GO:0004428;inositol or phosphatidylinositol kinase activity;0.0490789940290652!GO:0004402;histone acetyltransferase activity;0.0493381612353295!GO:0004468;lysine N-acetyltransferase activity;0.0493381612353295!GO:0008213;protein amino acid alkylation;0.0495274974818889!GO:0006479;protein amino acid methylation;0.0495274974818889 | |||
|sample_id=10823 | |||
|sample_note= | |||
|sample_sex=female | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=POU2F1..3:2.37041826617;POU5F1:2.19357996837;HOXA9_MEIS1:1.9820005443;DMAP1_NCOR{1,2}_SMARC:1.93753310364;NFKB1_REL_RELA:1.88454308597;PAX6:1.83815824765;E2F1..5:1.66746562237;NFY{A,B,C}:1.61773653537;PDX1:1.61324370331;MYB:1.60991349116;IRF7:1.57365992701;ELF1,2,4:1.5678364964;IRF1,2:1.51029513615;ELK1,4_GABP{A,B1}:1.50927736904;AIRE:1.49872807127;NKX6-1,2:1.40257422802;PITX1..3:1.34016609735;TOPORS:1.27979895404;SPI1:1.09819733832;YY1:1.09624363262;VSX1,2:1.09189264097;HIF1A:1.00233337086;RUNX1..3:0.958333536542;FOXA2:0.938267184563;CDX1,2,4:0.932634597613;NRF1:0.917827322361;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.874782217273;PAX3,7:0.867746317015;PAX8:0.834739262651;ZBTB16:0.747432493176;SPIB:0.743488815208;ZNF143:0.740075913508;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.731695537187;POU1F1:0.679921587167;RBPJ:0.675027664415;AHR_ARNT_ARNT2:0.645625869143;ETS1,2:0.643138666976;OCT4_SOX2{dimer}:0.616760528987;MYOD1:0.564347942058;EVI1:0.517866932713;FOXP3:0.51314630871;BREu{core}:0.483195567593;HNF4A_NR2F1,2:0.481010213497;LMO2:0.45816833409;POU3F1..4:0.451495795201;SNAI1..3:0.445885606129;NR5A1,2:0.441842885738;GFI1:0.425449336341;FOXP1:0.420256678772;SPZ1:0.416396655147;NKX2-2,8:0.413254415911;ZNF384:0.398427782303;ZEB1:0.393141169649;CUX2:0.367008262589;ESRRA:0.34488416334;RORA:0.341468289947;PBX1:0.327464552073;HNF1A:0.318475029335;ARID5B:0.299849604422;FOXN1:0.283588409682;CDC5L:0.219548502348;HSF1,2:0.217125661908;NANOG{mouse}:0.212561126276;GATA6:0.185705424925;STAT1,3:0.181699498951;RFX2..5_RFXANK_RFXAP:0.181529364036;ALX4:0.175426672194;FOX{F1,F2,J1}:0.172798725348;SOX{8,9,10}:0.156916122192;ATF5_CREB3:0.11407071491;TGIF1:0.0970735125656;ESR1:0.0885747640974;CRX:0.0790686360018;IKZF2:0.078620757849;PRRX1,2:0.0757602491704;LHX3,4:0.0731297292607;TFDP1:0.0592301017446;RXRA_VDR{dimer}:0.0524905420829;PAX2:0.0243553982515;NKX3-2:-0.00946612243698;HES1:-0.0103882197375;TP53:-0.0248525305369;CREB1:-0.0915954864285;PRDM1:-0.112168379044;bHLH_family:-0.141380649767;NKX2-3_NKX2-5:-0.145715604126;FOXQ1:-0.146672303626;EBF1:-0.152619767882;SOX5:-0.171044940095;NR1H4:-0.171457310599;PAX4:-0.202124160018;NFE2:-0.229810458963;ATF4:-0.230366473365;DBP:-0.237831449627;TLX2:-0.241852673121;MEF2{A,B,C,D}:-0.249252057959;LEF1_TCF7_TCF7L1,2:-0.278211047761;BPTF:-0.296763365785;HAND1,2:-0.304390242869;SRF:-0.334628178397;EP300:-0.390234042756;ALX1:-0.391391531104;GATA4:-0.413959866104;HOX{A5,B5}:-0.418150119657;ADNP_IRX_SIX_ZHX:-0.43834722201;HBP1_HMGB_SSRP1_UBTF:-0.442831407362;HOX{A4,D4}:-0.446136280294;NFATC1..3:-0.469194168639;FOS_FOS{B,L1}_JUN{B,D}:-0.47580072585;RXR{A,B,G}:-0.487865268285;TEF:-0.493257045261;AR:-0.505828926121;GFI1B:-0.511146385668;SOX17:-0.519680026523;NR6A1:-0.550791796542;SOX2:-0.560507912013;KLF4:-0.584431356653;FOSL2:-0.58658511533;NKX2-1,4:-0.592512316824;ONECUT1,2:-0.603083014679;BACH2:-0.606519400499;HMGA1,2:-0.618924271622;ZFP161:-0.639488788223;UFEwm:-0.640450560739;EN1,2:-0.64289009084;STAT2,4,6:-0.657564393;IKZF1:-0.682032376795;RREB1:-0.685940158176;CEBPA,B_DDIT3:-0.688195997655;NFIL3:-0.699361114087;GLI1..3:-0.734260517816;MZF1:-0.739685154939;TFAP4:-0.74098921276;SMAD1..7,9:-0.754455638358;MYBL2:-0.766991593172;STAT5{A,B}:-0.782479505782;GCM1,2:-0.784829374914;HOX{A6,A7,B6,B7}:-0.803687033526;NKX3-1:-0.818993250626;PPARG:-0.82056527378;PAX1,9:-0.826713516328;SREBF1,2:-0.836657185559;ATF2:-0.843870436334;HLF:-0.846440132248;NHLH1,2:-0.861330245316;TAL1_TCF{3,4,12}:-0.914148726196;ZNF148:-0.923810945583;MYFfamily:-0.924009766946;FOXD3:-0.928959043952;ZNF423:-0.957188083363;MTF1:-0.963145026819;EGR1..3:-0.977760003256;ZIC1..3:-0.992846577728;RFX1:-1.01291870628;XCPE1{core}:-1.03851626774;FOXO1,3,4:-1.0471811307;MTE{core}:-1.06487027425;TBP:-1.08372042353;HIC1:-1.08986749596;JUN:-1.1058763335;T:-1.12366012248;REST:-1.13330000012;NFIX:-1.14587520621;PAX5:-1.15753204538;GTF2I:-1.18459570894;NFE2L2:-1.21223264823;XBP1:-1.23331964364;NFE2L1:-1.24787716658;MAFB:-1.27537639605;MED-1{core}:-1.2857994497;FOXM1:-1.2922012403;NANOG:-1.30990483605;TFAP2{A,C}:-1.32150589921;PATZ1:-1.34822630122;TFCP2:-1.35779454385;ATF6:-1.37025780055;GTF2A1,2:-1.38000243687;HMX1:-1.388945926;GZF1:-1.43654812128;TBX4,5:-1.46044857331;MAZ:-1.47340187805;ZNF238:-1.47592322241;TLX1..3_NFIC{dimer}:-1.48167347747;ZBTB6:-1.63966328517;POU6F1:-1.67507898292;TEAD1:-1.68001545219;NR3C1:-1.68460187491;FOX{D1,D2}:-1.72871992526;SP1:-1.81297752058;TFAP2B:-1.90774420056;FOX{I1,J2}:-2.13253849766;FOXL1:-2.4673002322 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10823-111C4;search_select_hide=table117:FF:10823-111C4 | |||
}} | }} |
Latest revision as of 15:07, 3 June 2020
Name: | B lymphoblastoid cell line: GM12878 ENCODE, biol_rep3 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs12333 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12333
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12333
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.00798 |
10 | 10 | 0.026 |
100 | 100 | 0.387 |
101 | 101 | 0.222 |
102 | 102 | 0.542 |
103 | 103 | 0.164 |
104 | 104 | 0.556 |
105 | 105 | 0.639 |
106 | 106 | 0.899 |
107 | 107 | 0.56 |
108 | 108 | 0.943 |
109 | 109 | 0.0728 |
11 | 11 | 0.252 |
110 | 110 | 0.154 |
111 | 111 | 0.0613 |
112 | 112 | 0.157 |
113 | 113 | 0.579 |
114 | 114 | 0.48 |
115 | 115 | 0.428 |
116 | 116 | 0.495 |
117 | 117 | 0.0215 |
118 | 118 | 0.129 |
119 | 119 | 0.228 |
12 | 12 | 0.983 |
120 | 120 | 0.374 |
121 | 121 | 0.964 |
122 | 122 | 0.594 |
123 | 123 | 3.87578e-5 |
124 | 124 | 0.0505 |
125 | 125 | 0.443 |
126 | 126 | 0.287 |
127 | 127 | 0.301 |
128 | 128 | 0.662 |
129 | 129 | 0.681 |
13 | 13 | 0.0845 |
130 | 130 | 0.62 |
131 | 131 | 0.424 |
132 | 132 | 0.672 |
133 | 133 | 0.659 |
134 | 134 | 0.666 |
135 | 135 | 0.995 |
136 | 136 | 0.102 |
137 | 137 | 0.741 |
138 | 138 | 0.924 |
139 | 139 | 0.406 |
14 | 14 | 0.774 |
140 | 140 | 0.291 |
141 | 141 | 0.0513 |
142 | 142 | 0.763 |
143 | 143 | 0.495 |
144 | 144 | 0.661 |
145 | 145 | 0.0604 |
146 | 146 | 0.758 |
147 | 147 | 0.25 |
148 | 148 | 0.0662 |
149 | 149 | 0.371 |
15 | 15 | 0.0611 |
150 | 150 | 0.985 |
151 | 151 | 0.682 |
152 | 152 | 0.0703 |
153 | 153 | 0.852 |
154 | 154 | 0.993 |
155 | 155 | 0.116 |
156 | 156 | 0.777 |
157 | 157 | 0.124 |
158 | 158 | 0.854 |
159 | 159 | 0.129 |
16 | 16 | 0.9 |
160 | 160 | 0.194 |
161 | 161 | 0.0311 |
162 | 162 | 0.951 |
163 | 163 | 0.743 |
164 | 164 | 0.128 |
165 | 165 | 0.646 |
166 | 166 | 0.289 |
167 | 167 | 0.32 |
168 | 168 | 0.277 |
169 | 169 | 0.659 |
17 | 17 | 0.868 |
18 | 18 | 0.802 |
19 | 19 | 0.584 |
2 | 2 | 0.621 |
20 | 20 | 0.299 |
21 | 21 | 0.177 |
22 | 22 | 0.992 |
23 | 23 | 0.294 |
24 | 24 | 0.192 |
25 | 25 | 0.093 |
26 | 26 | 0.0622 |
27 | 27 | 0.519 |
28 | 28 | 0.375 |
29 | 29 | 0.0279 |
3 | 3 | 0.0553 |
30 | 30 | 0.106 |
31 | 31 | 0.765 |
32 | 32 | 0.425 |
33 | 33 | 0.293 |
34 | 34 | 0.604 |
35 | 35 | 0.161 |
36 | 36 | 0.0353 |
37 | 37 | 0.366 |
38 | 38 | 0.39 |
39 | 39 | 0.439 |
4 | 4 | 0.788 |
40 | 40 | 0.434 |
41 | 41 | 0.759 |
42 | 42 | 0.0758 |
43 | 43 | 0.452 |
44 | 44 | 0.177 |
45 | 45 | 0.38 |
46 | 46 | 0.239 |
47 | 47 | 0.0382 |
48 | 48 | 0.062 |
49 | 49 | 0.316 |
5 | 5 | 0.681 |
50 | 50 | 0.879 |
51 | 51 | 0.755 |
52 | 52 | 0.252 |
53 | 53 | 0.34 |
54 | 54 | 0.658 |
55 | 55 | 0.456 |
56 | 56 | 0.773 |
57 | 57 | 0.213 |
58 | 58 | 0.0771 |
59 | 59 | 0.32 |
6 | 6 | 0.872 |
60 | 60 | 0.855 |
61 | 61 | 0.136 |
62 | 62 | 0.0874 |
63 | 63 | 0.727 |
64 | 64 | 0.214 |
65 | 65 | 0.982 |
66 | 66 | 0.389 |
67 | 67 | 0.8 |
68 | 68 | 0.0539 |
69 | 69 | 0.501 |
7 | 7 | 0.114 |
70 | 70 | 0.454 |
71 | 71 | 0.0165 |
72 | 72 | 0.302 |
73 | 73 | 0.866 |
74 | 74 | 0.826 |
75 | 75 | 0.00987 |
76 | 76 | 0.507 |
77 | 77 | 0.562 |
78 | 78 | 0.0159 |
79 | 79 | 0.855 |
8 | 8 | 0.722 |
80 | 80 | 0.104 |
81 | 81 | 0.454 |
82 | 82 | 0.719 |
83 | 83 | 0.402 |
84 | 84 | 0.218 |
85 | 85 | 0.243 |
86 | 86 | 0.348 |
87 | 87 | 0.126 |
88 | 88 | 0.692 |
89 | 89 | 0.957 |
9 | 9 | 0.914 |
90 | 90 | 0.329 |
91 | 91 | 0.552 |
92 | 92 | 0.722 |
93 | 93 | 0.268 |
94 | 94 | 0.783 |
95 | 95 | 0.0207 |
96 | 96 | 0.807 |
97 | 97 | 0.148 |
98 | 98 | 0.509 |
99 | 99 | 0.289 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs12333
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0102062 B-lymphoblastoid cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0002371 (somatic cell)
0000542 (lymphocyte)
0000219 (motile cell)
0000945 (lymphocyte of B lineage)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0002242 (nucleate cell)
0000255 (eukaryotic cell)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0101035 (hematopoietic cell line sample)
0100773 (lymphoblastoid cell line sample)
0101522 (B-lymphocyte cell line sample)
0102062 (B-lymphoblastoid cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000051 (common lymphoid progenitor)