FF:11454-119A5: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005417 | ||
|accession_numbers=CAGE;DRX008258;DRR009130;DRZ000555;DRZ001940;DRZ011905;DRZ013290 | |||
|ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0002097,UBERON:0002199,UBERON:0002384,UBERON:0000479,UBERON:0000064,UBERON:0010314,UBERON:0000062,UBERON:0004120,UBERON:0000061,UBERON:0000465,UBERON:0004923,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0003102,UBERON:0010317,UBERON:0002067,UBERON:0002416 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0002320,CL:0002371,CL:0000255,CL:0000057,CL:0002620,CL:0002551 | |||
| | |||
|ancestors_in_anatomy_facet=UBERON: | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000057,FF:0000250,FF:0000001,FF:0000062 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr7:19157248..19157268,-!p1@TWIST1!1.78!156.85!TWIST1;;chr1:170633348..170633399,+!p2@PRRX1!1.65!58.92!PRRX1;;chr1:170632285..170632309,+!p1@PRRX1!1.64!48.24!PRRX1;;chr12:66218255..66218304,+!p3@HMGA2!1.49!77.86!HMGA2;;chr6:34204921..34204939,+!p3@HMGA1!1.48!843.20!HMGA1;;chr19:46801639..46801699,+!p1@HIF3A!1.47!28.33!HIF3A;;chr12:54410664..54410684,+!p1@HOXC4,p1@HOXC5,p1@HOXC6!1.44!26.71!HOXC5;;chr12:66218598..66218645,+!p2@HMGA2!1.40!107.00!HMGA2;;chr1:170633262..170633285,+!p3@PRRX1!1.38!26.22!PRRX1;;chr12:66218212..66218244,+!p5@HMGA2!1.35!31.08!HMGA2;;chr5:2751762..2751784,-!p1@IRX2!1.32!20.07!IRX2;;chr12:66218183..66218209,+!p4@HMGA2!1.31!36.75!HMGA2;;chr20:55204351..55204377,+!p1@TFAP2C!1.31!24.44!TFAP2C;;chr2:239756739..239756755,+!p2@TWIST2!1.30!31.89!TWIST2;;chr15:57511609..57511651,+!p2@TCF12!1.22!26.06!TCF12;;chr2:239756671..239756732,+!p1@TWIST2!1.20!46.94!TWIST2;;chr6:85474299..85474324,-!p1@TBX18!1.19!26.06!TBX18;;chr17:46675558..46675577,-!p2@HOXB6!1.13!12.63!HOXB6;;chr2:102091566..102091581,-!p1@RFX8!1.11!11.82!RFX8;;chr18:52969844..52969895,-!p27@TCF4!1.08!11.01!TCF4;;chr15:83953397..83953425,-!p1@BNC1!1.02!11.01!BNC1;;chr12:54402745..54402788,+!p1@HOXC8!1.02!9.55!HOXC8;;chr1:170632439..170632465,+!p11@PRRX1!1.01!9.23!PRRX1;;chr2:5832508..5832524,+!p1@SOX11!1.00!8.90!SOX11;;chr2:176994408..176994492,+!p1@HOXD8!0.99!8.74!HOXD8;;chr2:19558373..19558392,-!p1@OSR1!0.98!24.12!OSR1;;chr5:3595977..3595999,+!p1@IRX1!0.97!8.42!IRX1;;chr20:42543441..42543497,+!p1@TOX2!0.96!37.39!TOX2;;chr17:41622765..41622821,-!p2@ETV4!0.96!12.63!ETV4;;chr17:46682321..46682362,-!p1@HOXB6!0.95!7.93!HOXB6;;chr17:46675420..46675465,-!p3@HOXB6!0.94!8.90!HOXB6;;chr12:54447637..54447659,+!p4@HOXC4!0.94!7.77!HOXC4;;chr12:66218378..66218401,+!p6@HMGA2!0.93!11.82!HMGA2;;chr3:12329358..12329393,+!p3@PPARG!0.91!18.29!PPARG;;chr2:200322654..200322707,-!p2@SATB2!0.91!10.52!SATB2;;chr3:147127142..147127168,+!p1@ZIC1!0.91!7.12!ZIC1;;chr17:41623009..41623053,-!p4@ETV4!0.90!11.49!ETV4;;chr1:170632477..170632506,+!p6@PRRX1!0.90!6.96!PRRX1;;chr8:93074848..93074871,-!p3@RUNX1T1!0.90!6.96!RUNX1T1;;chr18:52969674..52969685,-!p24@TCF4!0.89!6.80!TCF4;;chr17:46667628..46667642,-!p2@HOXB3!0.88!6.64!HOXB3;;chr5:158526917..158526932,-!p1@EBF1!0.87!16.51!EBF1;;chr3:157823517..157823562,-!p1@SHOX2!0.87!6.96!SHOX2;;chr8:93074803..93074845,-!p1@RUNX1T1!0.87!6.47!RUNX1T1;;chr1:170632250..170632277,+!p7@PRRX1!0.87!6.47!PRRX1;;chr1:54204818..54204870,-!p@chr1:54204818..54204870,-!0.86!6.64!GLIS1;;chr2:223163706..223163730,-!p1@PAX3!0.86!6.31!PAX3;;chr12:54410639..54410659,+!p2@HOXC4,p2@HOXC5,p2@HOXC6!0.86!6.31!HOXC5;;chr5:2751785..2751808,-!p2@IRX2!0.86!6.31!IRX2;;chr3:12329397..12329433,+!p2@PPARG!0.84!14.08!PPARG;;chr12:66218573..66218596,+!p7@HMGA2!0.84!9.06!HMGA2;;chr12:66218420..66218439,+!p12@HMGA2!0.84!5.99!HMGA2;;chr12:2986206..2986258,-!p2@FOXM1!0.83!37.55!FOXM1;;chr6:85474198..85474212,-!p3@TBX18!0.81!5.50!TBX18;;chrY:21906594..21906622,-!p1@KDM5D!0.81!5.50!KDM5D;;chr5:321810..321877,+!p1@AHRR!0.80!17.97!AHRR;;chr20:42543506..42543549,+!p2@TOX2!0.79!13.11!TOX2;;chr3:141121847..141121868,+!p5@ZBTB38!0.79!8.26!ZBTB38;;chr1:170632723..170632739,+!p8@PRRX1!0.79!5.18!PRRX1;;chr11:65667846..65667868,-!p1@FOSL1!0.78!144.07!FOSL1;;chr12:66218469..66218477,+!p16@HMGA2!0.78!5.02!HMGA2;;chrY:2803415..2803468,+!p1@ZFY!0.78!5.02!ZFY;;chr11:46299199..46299233,+!p1@CREB3L1!0.77!27.84!CREB3L1;;chr5:72744594..72744609,-!p1@FOXD1!0.77!24.12!FOXD1;;chr17:41277372..41277418,-!p1@BRCA1!0.77!19.10!BRCA1;;chr16:86544113..86544145,+!p1@FOXF1!0.77!6.15!FOXF1;;chr6:85473156..85473210,-!p2@TBX18!0.77!6.15!TBX18;;chr1:170632137..170632172,+!p10@PRRX1!0.77!4.86!PRRX1;;chr10:119303078..119303169,+!p2@EMX2!0.77!4.86!EMX2;;chr3:147111231..147111281,+!p3@ZIC1!0.77!4.86!ZIC1;;chr7:14029283..14029311,-!p1@ETV1!0.76!27.68!ETV1;;chr17:46687959..46688007,-!p2@HOXB7!0.76!6.80!HOXB7;;chr16:86612320..86612394,+!p1@FOXL1!0.76!4.69!FOXL1;;chr12:54378923..54378966,+!p1@HOXC10!0.76!4.69!HOXC10;;chr17:46622114..46622138,-!p4@HOXB2!0.75!7.45!HOXB2;;chr17:41623692..41623715,-!p1@ETV4!0.74!21.37!ETV4;;chr11:65686732..65686756,+!p2@DRAP1!0.74!21.04!DRAP1;;chr11:65686802..65686818,+!p6@DRAP1!0.74!8.26!DRAP1;;chr4:174450089..174450153,-!p2@HAND2!0.74!4.53!HAND2;;chr19:42636586..42636607,-!p1@POU2F2!0.73!13.11!POU2F2;;chr12:66218443..66218461,+!p8@HMGA2!0.73!5.83!HMGA2;;chr8:49833948..49833973,-!p2@SNAI2!0.72!29.95!SNAI2;;chr7:19157043..19157088,-!p2@TWIST1!0.72!11.65!TWIST1;;chr17:46667594..46667619,-!p1@HOXB3!0.72!4.21!HOXB3;;chr17:46671108..46671147,-!p1@HOXB5!0.72!4.21!HOXB5;;chr17:46622070..46622109,-!p1@HOXB2!0.71!9.87!HOXB2;;chr17:46690839..46690884,-!p1@HOXB8!0.70!4.05!HOXB8;;chr12:66218152..66218174,+!p10@HMGA2!0.69!4.21!HMGA2;;chr17:46691732..46691766,-!p4@HOXB8!0.69!3.88!HOXB8;;chr21:47063625..47063658,+!p1@PCBP3!0.68!18.78!PCBP3;;chr17:59477233..59477263,+!p1@TBX2!0.68!13.11!TBX2;;chr17:46688334..46688385,-!p1@HOXB7!0.68!5.83!HOXB7;;chr6:45390025..45390076,+!p2@RUNX2!0.67!9.71!RUNX2;;chr11:46299539..46299620,+!p2@CREB3L1!0.67!6.64!CREB3L1;;chr17:46655704..46655718,-!p2@HOXB4!0.67!5.83!HOXB4;;chr5:3595934..3595957,+!p2@IRX1!0.67!3.72!IRX1;;chr1:170632115..170632136,+!p9@PRRX1!0.67!3.72!PRRX1;;chr4:174451370..174451387,-!p1@HAND2!0.67!3.72!HAND2;;chr12:54393880..54393962,+!p1@HOXC9!0.67!3.72!HOXC9;;chr12:96588143..96588185,+!p1@ELK3!0.66!51.15!ELK3;;chr17:46622205..46622218,-!p3@HOXB2!0.66!4.21!HOXB2;;chr5:3595961..3595975,+!p3@IRX1!0.66!3.56!IRX1;;chr2:119604456..119604501,-!p2@EN1!0.66!3.56!EN1;;chr2:119605214..119605230,-!p1@EN1!0.66!3.56!EN1;;chr6:34204672..34204692,+!p1@HMGA1!0.65!455.02!HMGA1;;chr16:86600426..86600441,+!p1@FOXC2!0.65!9.55!FOXC2;;chr9:132427972..132428056,+!p1@PRRX2!0.65!4.69!PRRX2;;chr3:21792585..21792625,-!p2@ZNF385D!0.65!3.88!ZNF385D;;chr8:49833978..49833996,-!p1@SNAI2!0.64!81.75!SNAI2;;chr12:66218836..66218888,+!p1@HMGA2!0.64!36.75!HMGA2;;chr7:42276787..42276815,-!p1@GLI3!0.64!10.20!GLI3;;chr7:27205136..27205164,-!p1@HOXA9!0.64!3.40!HOXA9;;chr12:54402790..54402805,+!p2@HOXC8!0.64!3.40!HOXC8;;chr1:119530493..119530572,-!p1@TBX15!0.64!3.40!TBX15;;chr2:102091478..102091490,-!p3@RFX8!0.64!3.40!RFX8;;chr3:157824001..157824078,-!p2@SHOX2!0.64!3.40!SHOX2;;chr17:46675469..46675481,-!p4@HOXB6!0.64!3.40!HOXB6;;chr6:31126291..31126399,+!p1@TCF19!0.63!36.26!TCF19;;chr4:4861385..4861398,+!p1@MSX1!0.63!11.17!MSX1;;chr21:36260773..36260804,-!p7@RUNX1!0.63!4.69!RUNX1;;chr1:170633058..170633084,+!p5@PRRX1!0.63!3.24!PRRX1;;chr2:102091144..102091183,-!p2@RFX8!0.63!3.24!RFX8;;chr2:175199697..175199706,+!p2@SP9!0.63!3.24!SP9;;chr16:86600870..86600921,+!p2@FOXC2!0.63!3.24!FOXC2;;chr1:8926441..8926473,-!p10@ENO1!0.62!5.18!ENO1;;chr1:47779762..47779827,-!p1@STIL,p1@TAL1!0.61!16.67!TAL1;;chr19:22817119..22817145,+!p1@ZNF492!0.61!5.67!ZNF492;;chr1:170633245..170633256,+!p14@PRRX1!0.61!3.08!PRRX1;;chr12:54379029..54379057,+!p2@HOXC10!0.61!3.08!HOXC10;;chr12:54402729..54402743,+!p3@HOXC8!0.61!3.08!HOXC8;;chr12:66358080..66358094,+!p15@HMGA2!0.61!3.08!HMGA2;;chr5:158527139..158527161,-!p5@EBF1!0.61!3.08!EBF1;;chr14:55493763..55493824,-!p1@WDHD1!0.60!26.87!WDHD1;;chr17:41622925..41622976,-!p3@ETV4!0.60!4.86!ETV4;;chr19:38720294..38720348,-!p1@DPF1!0.60!3.88!DPF1;;chr5:138609782..138609826,+!p5@MATR3!0.59!22.34!MATR3;;chr2:169312600..169312606,+!p2@CERS6!0.59!5.02!CERS6;;chr12:54447599..54447630,+!p3@HOXC4!0.59!3.72!HOXC4;;chr12:54422217..54422239,+!p3@HOXC6!0.59!2.91!HOXC6;;chr3:141121820..141121838,+!p9@ZBTB38!0.59!2.91!ZBTB38;;chr5:158527104..158527135,-!p4@EBF1!0.59!2.91!EBF1;;chr6:34204973..34204990,+!p4@HMGA1!0.58!46.30!HMGA1;;chr12:115121962..115121987,-!p1@TBX3!0.58!28.81!TBX3;;chr1:8934931..8934947,-!p4@ENO1!0.58!11.01!ENO1;;chr11:19263192..19263222,-!p2@E2F8!0.58!3.56!E2F8;;chr8:128748308..128748324,+!p2@MYC!0.57!93.40!MYC;;chr1:170632959..170632987,+!p4@PRRX1!0.57!3.08!PRRX1;;chr1:170632762..170632786,+!p13@PRRX1!0.57!2.75!PRRX1;;chr17:46675539..46675551,-!p7@HOXB6!0.57!2.75!HOXB6;;chr2:102091590..102091601,-!p5@RFX8!0.57!2.75!RFX8;;chr3:147111198..147111225,+!p4@ZIC1!0.57!2.75!ZIC1;;chr3:21792631..21792665,-!p3@ZNF385D!0.57!2.75!ZNF385D;;chr12:3068544..3068597,+!p1@TEAD4!0.56!19.59!TEAD4;;chr3:37217736..37217753,-!p2@LRRFIP2!0.56!13.44!LRRFIP2;;chr14:61116183..61116208,-!p1@SIX1!0.56!11.98!SIX1;;chr3:12329320..12329338,+!p4@PPARG!0.56!2.91!PPARG;;chr2:96012353..96012378,+!p4@KCNIP3!0.56!2.59!KCNIP3;;chr4:299227..299272,-!p1@ZNF732!0.56!2.59!ZNF732;;chr12:54447686..54447704,+!p5@HOXC4!0.56!2.59!HOXC4;;chr17:46671504..46671541,-!p2@HOXB5!0.56!2.59!HOXB5;;chr17:46675586..46675600,-!p6@HOXB6!0.56!2.59!HOXB6;;chr7:44143925..44143970,+!p1@AEBP1!0.55!71.71!AEBP1;;chr5:176738887..176738934,-!p1@MXD3!0.55!21.21!MXD3;;chr11:113930291..113930339,+!p2@ZBTB16!0.54!4.53!ZBTB16;;chr1:170632647..170632659,+!p17@PRRX1!0.54!2.43!PRRX1;;chr17:41622731..41622764,-!p5@ETV4!0.54!2.43!ETV4;;chrX:136648643..136648711,+!p2@ZIC3!0.54!2.43!ZIC3;;chr12:2986275..2986363,-!p1@FOXM1!0.53!30.76!FOXM1;;chr7:42276822..42276895,-!p2@GLI3!0.53!8.58!GLI3;;chr17:41622834..41622883,-!p6@ETV4!0.53!3.08!ETV4;;chr16:54320675..54320715,-!p1@IRX3!0.52!5.83!IRX3;;chr4:206390..206444,+!p1@ZNF876P!0.52!4.69!ZNF876P;;chr20:42295745..42295765,+!p1@MYBL2!0.51!47.43!MYBL2;;chr20:39946361..39946379,-!p2@ZHX3!0.51!8.26!ZHX3;;chr4:26322267..26322334,+!p3@RBPJ!0.51!6.47!RBPJ;;chr2:185463247..185463263,+!p1@ZNF804A!0.51!4.53!ZNF804A;;chr12:66218003..66218018,+!p9@HMGA2!0.51!2.91!HMGA2;;chr12:54380404..54380433,+!p3@HOXC10!0.51!2.27!HOXC10;;chr12:54394309..54394336,+!p2@HOXC9!0.51!2.27!HOXC9;;chr2:96012397..96012417,+!p3@KCNIP3!0.51!2.27!KCNIP3;;chr3:147127177..147127194,+!p2@ZIC1!0.51!2.27!ZIC1;;chr19:57352087..57352102,-!p1@PEG3,p1@ZIM2!0.51!2.27!PEG3;;chr1:170632310..170632321,+!p15@PRRX1!0.51!2.27!PRRX1;;chr7:27205106..27205134,-!p2@HOXA9!0.51!2.27!HOXA9;;chr8:25902876..25902936,-!p1@EBF2!0.51!2.27!EBF2;;chr12:77459306..77459365,-!p1@E2F7!0.50!35.61!E2F7;;chr20:42295713..42295738,+!p2@MYBL2!0.50!16.5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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000057;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000222;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0002551;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0002620;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002067;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002097;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002416 | |||
|ffid_belonging_in_development=CL:0000134 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 41: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|top_motifs= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520Dermal%252c%2520donor5.CNhs12055.11454-119A5.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520Dermal%252c%2520donor5.CNhs12055.11454-119A5.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520Dermal%252c%2520donor5.CNhs12055.11454-119A5.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520Dermal%252c%2520donor5.CNhs12055.11454-119A5.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520Dermal%252c%2520donor5.CNhs12055.11454-119A5.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11454-119A5 | |||
|is_a=EFO:0002091;;FF:0000062 | |||
|is_obsolete= | |||
|library_id=CNhs12055 | |||
|library_id_phase_based=2:CNhs12055 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11454 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11454 | |||
|name=Fibroblast - Dermal, donor5 | |||
|namespace=FANTOM5 | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs12055,LSID838,release011,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,-0.160318030086386,0,-0.212203493447947,0.147701427826032,0,0,0,0,0,0,0,0,0,0,0,0.0651586387455666,0,0.338647428462356,0,0.147369494509197,0,0,0,0.196781092750337,0,0,0.124569528610739,0,0,0,0,0,0,0,0,0,0,0.171907396292758,0,0.0561531765461276,0.0169365635065124,0,0,0,0,0,0,0,-0.0242150211128343,0,0,0,0.329013375992186,0,0,0,-0.0969923612426051,0,0,0.119479628522012,0,0,0,0,0,0,0,0,0.0651586387455666,0,0,0,0,0,0,0,0,0,0.0934816315200053,0,0,0,0,0,-0.0115518997947441,0.0325793193727833,0,0,-0.0139750729964334,-0.125243704549489,0,0.0651586387455666,0.0325793193727833,0,-0.0980353512377064,0.00251374643944275,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.149611625482931,0,0,0,-0.121778579634628,-0.496710178663459,0,0,0,0,0,0 | |||
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| |||
|rna_box=119 | |||
|rna_catalog_number=SC2305 | |||
|rna_concentration=0.551 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-TRIzol-isopropanol-v1.0 | |||
|rna_lot_number=4823 | |||
|rna_od260/230= | |||
|rna_od260/280= | |||
|rna_position=A5 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=119A5 | |||
|rna_weight_ug=10 | |||
|sample_age=fetal | |||
|sample_category=primary cells | |||
|sample_cell_catalog=N/A | |||
|sample_cell_line= | |||
|sample_cell_lot=N/A | |||
|sample_cell_type=fibroblast | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=Sciencell/3H | |||
|sample_description= | |||
|sample_dev_stage=fetus | |||
|sample_disease= | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=unknown | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.35407416312134e-280!GO:0043226;organelle;1.89004915872599e-231!GO:0043229;intracellular organelle;5.14884737662412e-231!GO:0043231;intracellular membrane-bound organelle;8.03815878165384e-226!GO:0043227;membrane-bound organelle;8.97323305994604e-226!GO:0005737;cytoplasm;2.65812438903088e-183!GO:0044422;organelle part;1.2988440854288e-170!GO:0044446;intracellular organelle part;6.72104046921088e-169!GO:0044444;cytoplasmic part;1.37338959477881e-126!GO:0032991;macromolecular complex;6.06555754489118e-118!GO:0044237;cellular metabolic process;2.08563120341486e-110!GO:0044238;primary metabolic process;3.23191442565974e-110!GO:0005634;nucleus;4.72892924801351e-109!GO:0030529;ribonucleoprotein complex;1.09624739124492e-104!GO:0043170;macromolecule metabolic process;1.42451436794119e-102!GO:0044428;nuclear part;4.04381141217529e-91!GO:0043233;organelle lumen;2.02785239615913e-87!GO:0031974;membrane-enclosed lumen;2.02785239615913e-87!GO:0003723;RNA binding;3.97832009525168e-82!GO:0005739;mitochondrion;3.59681221915189e-74!GO:0005515;protein binding;7.20205194679376e-72!GO:0043283;biopolymer metabolic process;2.01162609286463e-62!GO:0005840;ribosome;2.01162609286463e-62!GO:0006396;RNA processing;1.62543715646856e-60!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;5.84657759091331e-60!GO:0043234;protein complex;2.55995625226252e-58!GO:0006412;translation;3.11112325833816e-57!GO:0010467;gene expression;1.76349742116009e-56!GO:0003735;structural constituent of ribosome;8.14111612500156e-55!GO:0016043;cellular component organization and biogenesis;3.08366007643126e-54!GO:0031981;nuclear lumen;3.20086663451752e-53!GO:0044429;mitochondrial part;7.99701442212462e-51!GO:0019538;protein metabolic process;1.24988690869823e-50!GO:0031090;organelle membrane;1.84928025469311e-49!GO:0043228;non-membrane-bound organelle;4.50094367318587e-48!GO:0043232;intracellular non-membrane-bound organelle;4.50094367318587e-48!GO:0009058;biosynthetic process;3.52996622501108e-47!GO:0031967;organelle envelope;6.8369860861824e-47!GO:0033279;ribosomal subunit;9.9898255514805e-47!GO:0031975;envelope;1.86233938743091e-46!GO:0044249;cellular biosynthetic process;3.29589547941229e-45!GO:0044260;cellular macromolecule metabolic process;4.89472605583588e-45!GO:0016071;mRNA metabolic process;5.8198558592846e-45!GO:0044267;cellular protein metabolic process;1.05648050190594e-44!GO:0006259;DNA metabolic process;3.40993006357203e-43!GO:0006996;organelle organization and biogenesis;1.06878192995863e-42!GO:0009059;macromolecule biosynthetic process;3.28478741831591e-42!GO:0008380;RNA splicing;1.11344094964339e-41!GO:0015031;protein transport;3.22357244486717e-41!GO:0033036;macromolecule localization;7.29263980219987e-41!GO:0005829;cytosol;3.58835782067856e-40!GO:0003676;nucleic acid binding;7.76321466584506e-39!GO:0006397;mRNA processing;9.3257405762461e-39!GO:0022613;ribonucleoprotein complex biogenesis and assembly;2.69715732582346e-38!GO:0065003;macromolecular complex assembly;1.97015674384105e-37!GO:0045184;establishment of protein localization;3.72719243333985e-37!GO:0008104;protein localization;5.25286786475512e-37!GO:0046907;intracellular transport;6.54955434367018e-36!GO:0007049;cell cycle;2.65231600190781e-34!GO:0005830;cytosolic ribosome (sensu Eukaryota);2.07874572147938e-33!GO:0022607;cellular component assembly;2.08449876832763e-33!GO:0005654;nucleoplasm;4.01855977124717e-32!GO:0005740;mitochondrial envelope;2.78411057821525e-31!GO:0006886;intracellular protein transport;1.35326906203897e-29!GO:0005681;spliceosome;2.09475968541892e-29!GO:0031966;mitochondrial membrane;3.16993134703673e-29!GO:0019866;organelle inner membrane;1.44191857240046e-28!GO:0000166;nucleotide binding;1.48254600483394e-28!GO:0022402;cell cycle process;4.03473162351486e-27!GO:0016070;RNA metabolic process;6.98572884332305e-27!GO:0000278;mitotic cell cycle;1.28578703325385e-26!GO:0005743;mitochondrial inner membrane;2.34147084949761e-26!GO:0006974;response to DNA damage stimulus;3.68726971830259e-26!GO:0044451;nucleoplasm part;9.12243977331454e-26!GO:0044445;cytosolic part;1.1055809041535e-25!GO:0005694;chromosome;1.25449900390317e-25!GO:0015934;large ribosomal subunit;5.10433847926717e-24!GO:0031980;mitochondrial lumen;7.34562259405975e-24!GO:0005759;mitochondrial matrix;7.34562259405975e-24!GO:0015935;small ribosomal subunit;7.38927423700312e-24!GO:0044427;chromosomal part;4.01648094969703e-23!GO:0016462;pyrophosphatase activity;1.01778911066125e-22!GO:0006119;oxidative phosphorylation;1.39858072622381e-22!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.39858072622381e-22!GO:0051649;establishment of cellular localization;1.43041088152987e-22!GO:0022403;cell cycle phase;1.73831662851221e-22!GO:0051641;cellular localization;1.81761342784581e-22!GO:0016817;hydrolase activity, acting on acid anhydrides;2.25301638953946e-22!GO:0006281;DNA repair;3.91767696059711e-22!GO:0017111;nucleoside-triphosphatase activity;3.99874359424109e-22!GO:0005730;nucleolus;6.00933848097525e-22!GO:0000087;M phase of mitotic cell cycle;8.1536303177592e-22!GO:0007067;mitosis;2.30918897761363e-21!GO:0044455;mitochondrial membrane part;2.47250506014488e-21!GO:0012505;endomembrane system;8.50702707034764e-21!GO:0006457;protein folding;9.12651588056918e-21!GO:0022618;protein-RNA complex assembly;4.18427723440522e-20!GO:0051301;cell division;5.42622272637222e-20!GO:0016874;ligase activity;7.1904675071623e-20!GO:0017076;purine nucleotide binding;1.4043238827408e-19!GO:0032553;ribonucleotide binding;1.4043238827408e-19!GO:0032555;purine ribonucleotide binding;1.4043238827408e-19!GO:0000279;M phase;2.86644395469095e-19!GO:0051276;chromosome organization and biogenesis;2.99961855652257e-19!GO:0009719;response to endogenous stimulus;6.75777091512537e-19!GO:0042254;ribosome biogenesis and assembly;9.59236293734859e-19!GO:0006260;DNA replication;4.07305806533146e-18!GO:0005761;mitochondrial ribosome;9.08667536253669e-18!GO:0000313;organellar ribosome;9.08667536253669e-18!GO:0005746;mitochondrial respiratory chain;1.0433515077272e-17!GO:0005524;ATP binding;1.0433515077272e-17!GO:0006512;ubiquitin cycle;1.36824162188882e-17!GO:0048770;pigment granule;1.58445964032371e-17!GO:0042470;melanosome;1.58445964032371e-17!GO:0008135;translation factor activity, nucleic acid binding;1.86189811110181e-17!GO:0032559;adenyl ribonucleotide binding;2.57853348426008e-17!GO:0030554;adenyl nucleotide binding;4.08711198389417e-17!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);5.62957879573144e-17!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;6.09140755609177e-17!GO:0044265;cellular macromolecule catabolic process;7.33137062921497e-17!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.85590057857937e-16!GO:0005635;nuclear envelope;2.38918699493744e-16!GO:0051186;cofactor metabolic process;2.51785818624738e-16!GO:0051603;proteolysis involved in cellular protein catabolic process;3.81593688270026e-16!GO:0043285;biopolymer catabolic process;4.0218073073237e-16!GO:0006511;ubiquitin-dependent protein catabolic process;4.95811015161853e-16!GO:0050136;NADH dehydrogenase (quinone) activity;5.0572549134163e-16!GO:0003954;NADH dehydrogenase activity;5.0572549134163e-16!GO:0008137;NADH dehydrogenase (ubiquinone) activity;5.0572549134163e-16!GO:0019941;modification-dependent protein catabolic process;5.59781722401209e-16!GO:0043632;modification-dependent macromolecule catabolic process;5.59781722401209e-16!GO:0000398;nuclear mRNA splicing, via spliceosome;8.47547365702202e-16!GO:0000375;RNA splicing, via transesterification reactions;8.47547365702202e-16!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;8.47547365702202e-16!GO:0044257;cellular protein catabolic process;1.03377422123881e-15!GO:0000502;proteasome complex (sensu Eukaryota);1.45836079611907e-15!GO:0031965;nuclear membrane;2.44200257727641e-15!GO:0005783;endoplasmic reticulum;2.49167822362169e-15!GO:0044453;nuclear membrane part;4.30251791458841e-15!GO:0009057;macromolecule catabolic process;4.68914062656277e-15!GO:0006605;protein targeting;5.70346664065515e-15!GO:0006325;establishment and/or maintenance of chromatin architecture;1.03646216195491e-14!GO:0044432;endoplasmic reticulum part;2.31284553782618e-14!GO:0042775;organelle ATP synthesis coupled electron transport;2.46190407261866e-14!GO:0042773;ATP synthesis coupled electron transport;2.46190407261866e-14!GO:0030964;NADH dehydrogenase complex (quinone);2.92218755014656e-14!GO:0045271;respiratory chain complex I;2.92218755014656e-14!GO:0005747;mitochondrial respiratory chain complex I;2.92218755014656e-14!GO:0051082;unfolded protein binding;3.73613262193837e-14!GO:0006323;DNA packaging;4.31332092956208e-14!GO:0008134;transcription factor binding;4.32887371938115e-14!GO:0030163;protein catabolic process;6.3379734174757e-14!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;7.9720959815454e-14!GO:0003743;translation initiation factor activity;8.43593796325595e-14!GO:0006399;tRNA metabolic process;8.68468526635184e-14!GO:0048193;Golgi vesicle transport;1.37992479771142e-13!GO:0044248;cellular catabolic process;1.41567142817933e-13!GO:0043412;biopolymer modification;2.96436528631282e-13!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;2.99173496326223e-13!GO:0016887;ATPase activity;6.90085298864923e-13!GO:0042623;ATPase activity, coupled;7.90116412017648e-13!GO:0006413;translational initiation;9.13284861239631e-13!GO:0006732;coenzyme metabolic process;1.24367647735074e-12!GO:0005794;Golgi apparatus;1.41026374489288e-12!GO:0016604;nuclear body;1.44179370566643e-12!GO:0005643;nuclear pore;1.50958380755982e-12!GO:0006364;rRNA processing;1.61775809671627e-12!GO:0000074;regulation of progression through cell cycle;2.8707522644932e-12!GO:0051726;regulation of cell cycle;3.02800999714176e-12!GO:0065004;protein-DNA complex assembly;4.19383570603573e-12!GO:0000785;chromatin;5.68293993706681e-12!GO:0016072;rRNA metabolic process;6.09694417267081e-12!GO:0004386;helicase activity;8.5686037150818e-12!GO:0005793;ER-Golgi intermediate compartment;1.02029232845226e-11!GO:0006464;protein modification process;1.69568059294638e-11!GO:0009055;electron carrier activity;1.76089015438941e-11!GO:0006333;chromatin assembly or disassembly;2.17776893857924e-11!GO:0006913;nucleocytoplasmic transport;2.28259048170164e-11!GO:0065002;intracellular protein transport across a membrane;2.38209929644614e-11!GO:0009259;ribonucleotide metabolic process;4.32788391013606e-11!GO:0015630;microtubule cytoskeleton;4.32943596311719e-11!GO:0050657;nucleic acid transport;5.2721975698349e-11!GO:0051236;establishment of RNA localization;5.2721975698349e-11!GO:0050658;RNA transport;5.2721975698349e-11!GO:0051169;nuclear transport;5.91836705459217e-11!GO:0006403;RNA localization;6.06403857741915e-11!GO:0006446;regulation of translational initiation;6.48836549795073e-11!GO:0046930;pore complex;8.82440288300608e-11!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.0681031908324e-10!GO:0004812;aminoacyl-tRNA ligase activity;1.0681031908324e-10!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.0681031908324e-10!GO:0006163;purine nucleotide metabolic process;1.21355647512607e-10!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.74323583692975e-10!GO:0008026;ATP-dependent helicase activity;2.10500467897354e-10!GO:0043038;amino acid activation;3.02925097498706e-10!GO:0006418;tRNA aminoacylation for protein translation;3.02925097498706e-10!GO:0043039;tRNA aminoacylation;3.02925097498706e-10!GO:0043687;post-translational protein modification;4.52878714391662e-10!GO:0006461;protein complex assembly;4.96868639679435e-10!GO:0005789;endoplasmic reticulum membrane;5.60325965654907e-10!GO:0000775;chromosome, pericentric region;5.7538315523587e-10!GO:0009150;purine ribonucleotide metabolic process;5.77806994817268e-10!GO:0016607;nuclear speck;7.68855714855883e-10!GO:0016192;vesicle-mediated transport;8.27290189755808e-10!GO:0006334;nucleosome assembly;8.85150457182279e-10!GO:0009260;ribonucleotide biosynthetic process;9.4446911296784e-10!GO:0006164;purine nucleotide biosynthetic process;1.01836611492295e-09!GO:0008565;protein transporter activity;1.23863378744023e-09!GO:0008639;small protein conjugating enzyme activity;1.3920558657422e-09!GO:0030532;small nuclear ribonucleoprotein complex;1.44497375077166e-09!GO:0005819;spindle;1.73152347094305e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.75948035272178e-09!GO:0050794;regulation of cellular process;1.76068444308118e-09!GO:0003697;single-stranded DNA binding;1.87344655538731e-09!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;2.39647898731056e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;3.21603755267201e-09!GO:0009060;aerobic respiration;3.26429611533786e-09!GO:0004842;ubiquitin-protein ligase activity;3.33995308133601e-09!GO:0051028;mRNA transport;3.46246842734685e-09!GO:0031497;chromatin assembly;3.80151037946743e-09!GO:0009152;purine ribonucleotide biosynthetic process;4.84179819747756e-09!GO:0003712;transcription cofactor activity;5.27631900548634e-09!GO:0016779;nucleotidyltransferase activity;5.3909664984817e-09!GO:0043566;structure-specific DNA binding;5.50321790025202e-09!GO:0006261;DNA-dependent DNA replication;5.50321790025202e-09!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;5.74001735840817e-09!GO:0009199;ribonucleoside triphosphate metabolic process;6.80285773956539e-09!GO:0009141;nucleoside triphosphate metabolic process;8.44885329297002e-09!GO:0045333;cellular respiration;8.4738077878533e-09!GO:0019787;small conjugating protein ligase activity;9.32130387607259e-09!GO:0006888;ER to Golgi vesicle-mediated transport;1.16358703741863e-08!GO:0005813;centrosome;1.23067746938465e-08!GO:0017038;protein import;1.32734406946636e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.52165833762355e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.6206847185986e-08!GO:0009144;purine nucleoside triphosphate metabolic process;1.6206847185986e-08!GO:0016740;transferase activity;1.96381892149115e-08!GO:0051188;cofactor biosynthetic process;2.4711946261428e-08!GO:0006366;transcription from RNA polymerase II promoter;2.96545357856939e-08!GO:0016881;acid-amino acid ligase activity;4.22555526274218e-08!GO:0005815;microtubule organizing center;4.31397783480947e-08!GO:0006099;tricarboxylic acid cycle;4.58678062303348e-08!GO:0046356;acetyl-CoA catabolic process;4.58678062303348e-08!GO:0007005;mitochondrion organization and biogenesis;6.03125772255283e-08!GO:0009117;nucleotide metabolic process;7.38966579162844e-08!GO:0005667;transcription factor complex;7.39204855577462e-08!GO:0012501;programmed cell death;9.77128215836142e-08!GO:0015986;ATP synthesis coupled proton transport;9.94655694866008e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;9.94655694866008e-08!GO:0009142;nucleoside triphosphate biosynthetic process;9.9869766063421e-08!GO:0009201;ribonucleoside triphosphate biosynthetic process;9.9869766063421e-08!GO:0030120;vesicle coat;1.01816316569629e-07!GO:0030662;coated vesicle membrane;1.01816316569629e-07!GO:0046034;ATP metabolic process;1.15886666939002e-07!GO:0003899;DNA-directed RNA polymerase activity;1.15906479491167e-07!GO:0006084;acetyl-CoA metabolic process;1.18096097652988e-07!GO:0051329;interphase of mitotic cell cycle;1.29140382226033e-07!GO:0009109;coenzyme catabolic process;1.29140382226033e-07!GO:0009056;catabolic process;1.33887941167804e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.34049454713921e-07!GO:0016568;chromatin modification;1.37447917746733e-07!GO:0006915;apoptosis;1.60463489381579e-07!GO:0051187;cofactor catabolic process;2.03198246717012e-07!GO:0019829;cation-transporting ATPase activity;2.17331168309349e-07!GO:0005657;replication fork;2.24502981871796e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.38018008260741e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.38018008260741e-07!GO:0007051;spindle organization and biogenesis;2.94350991252033e-07!GO:0048475;coated membrane;3.09348759093934e-07!GO:0030117;membrane coat;3.09348759093934e-07!GO:0051325;interphase;3.54727233890531e-07!GO:0008094;DNA-dependent ATPase activity;3.90878284414228e-07!GO:0000245;spliceosome assembly;4.31380183460202e-07!GO:0019222;regulation of metabolic process;4.52889117249343e-07!GO:0015078;hydrogen ion transmembrane transporter activity;7.14706347271119e-07!GO:0032446;protein modification by small protein conjugation;7.72992446243832e-07!GO:0048523;negative regulation of cellular process;8.21864714660278e-07!GO:0016469;proton-transporting two-sector ATPase complex;9.22795005483116e-07!GO:0005762;mitochondrial large ribosomal subunit;9.36964551494744e-07!GO:0000315;organellar large ribosomal subunit;9.36964551494744e-07!GO:0003924;GTPase activity;9.6782653823222e-07!GO:0051246;regulation of protein metabolic process;1.05165905496161e-06!GO:0000075;cell cycle checkpoint;1.10522197498046e-06!GO:0008219;cell death;1.2145774998467e-06!GO:0016265;death;1.2145774998467e-06!GO:0016567;protein ubiquitination;1.29140647519787e-06!GO:0009108;coenzyme biosynthetic process;1.46901516494303e-06!GO:0005788;endoplasmic reticulum lumen;1.49282468242155e-06!GO:0006754;ATP biosynthetic process;1.59205925721896e-06!GO:0006753;nucleoside phosphate metabolic process;1.59205925721896e-06!GO:0045259;proton-transporting ATP synthase complex;1.70570653246525e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;2.36937727431794e-06!GO:0043623;cellular protein complex assembly;2.50503373965994e-06!GO:0016491;oxidoreductase activity;2.64151772437087e-06!GO:0000151;ubiquitin ligase complex;2.76151803906615e-06!GO:0044431;Golgi apparatus part;3.10112972912117e-06!GO:0006752;group transfer coenzyme metabolic process;3.55865417116529e-06!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;5.02557950036222e-06!GO:0051170;nuclear import;5.47172451431236e-06!GO:0050789;regulation of biological process;5.59701625002555e-06!GO:0005768;endosome;5.92295765411552e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;6.31840228599109e-06!GO:0019843;rRNA binding;6.62587208435631e-06!GO:0016853;isomerase activity;7.74577355406199e-06!GO:0016859;cis-trans isomerase activity;8.12706684244061e-06!GO:0005839;proteasome core complex (sensu Eukaryota);8.14106214760729e-06!GO:0000314;organellar small ribosomal subunit;8.73144749532752e-06!GO:0005763;mitochondrial small ribosomal subunit;8.73144749532752e-06!GO:0006613;cotranslational protein targeting to membrane;9.19242431106545e-06!GO:0006793;phosphorus metabolic process;9.52937285681589e-06!GO:0006796;phosphate metabolic process;9.52937285681589e-06!GO:0006091;generation of precursor metabolites and energy;9.52937285681589e-06!GO:0008654;phospholipid biosynthetic process;9.66935933651553e-06!GO:0007010;cytoskeleton organization and biogenesis;1.03423335451178e-05!GO:0006606;protein import into nucleus;1.14373607065614e-05!GO:0016126;sterol biosynthetic process;1.4947506439287e-05!GO:0000786;nucleosome;1.58711459626636e-05!GO:0051427;hormone receptor binding;1.59267558560969e-05!GO:0003724;RNA helicase activity;1.68220234232757e-05!GO:0005798;Golgi-associated vesicle;1.68355795544792e-05!GO:0006302;double-strand break repair;1.94986854321012e-05!GO:0048519;negative regulation of biological process;2.16022484976874e-05!GO:0016787;hydrolase activity;2.26550441137035e-05!GO:0007059;chromosome segregation;2.5151194835771e-05!GO:0000776;kinetochore;2.65160637311104e-05!GO:0003684;damaged DNA binding;2.7770583889765e-05!GO:0031252;leading edge;3.25253743606395e-05!GO:0016563;transcription activator activity;3.31327200641569e-05!GO:0045454;cell redox homeostasis;3.31327200641569e-05!GO:0044440;endosomal part;3.5764568449709e-05!GO:0010008;endosome membrane;3.5764568449709e-05!GO:0035257;nuclear hormone receptor binding;3.5764568449709e-05!GO:0015980;energy derivation by oxidation of organic compounds;3.72705923077157e-05!GO:0008033;tRNA processing;3.77339328281177e-05!GO:0031324;negative regulation of cellular metabolic process;3.77339328281177e-05!GO:0006310;DNA recombination;3.83203352425952e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;3.88620761403465e-05!GO:0043021;ribonucleoprotein binding;3.91178260385e-05!GO:0004298;threonine endopeptidase activity;4.23595667472576e-05!GO:0045786;negative regulation of progression through cell cycle;4.2594950768323e-05!GO:0044452;nucleolar part;5.26803781397388e-05!GO:0006916;anti-apoptosis;5.2821162862622e-05!GO:0016741;transferase activity, transferring one-carbon groups;5.3542546701551e-05!GO:0008168;methyltransferase activity;5.51830656530953e-05!GO:0016363;nuclear matrix;5.56582847879756e-05!GO:0005525;GTP binding;5.56582847879756e-05!GO:0000139;Golgi membrane;5.57542293444766e-05!GO:0031323;regulation of cellular metabolic process;6.0796029195444e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;6.51033990966194e-05!GO:0003713;transcription coactivator activity;6.87886566078395e-05!GO:0030867;rough endoplasmic reticulum membrane;7.05259245377022e-05!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;7.66322301042174e-05!GO:0051168;nuclear export;8.13612373061249e-05!GO:0016310;phosphorylation;8.14095381381912e-05!GO:0006383;transcription from RNA polymerase III promoter;8.38509911290584e-05!GO:0031968;organelle outer membrane;9.20638531976618e-05!GO:0005769;early endosome;9.28018465449086e-05!GO:0051052;regulation of DNA metabolic process;0.000103039415933549!GO:0009165;nucleotide biosynthetic process;0.00010312613856726!GO:0016564;transcription repressor activity;0.000107663321647393!GO:0019867;outer membrane;0.000109082158688463!GO:0006350;transcription;0.000135421737803838!GO:0006626;protein targeting to mitochondrion;0.000136537087812334!GO:0000059;protein import into nucleus, docking;0.000159767124018087!GO:0043681;protein import into mitochondrion;0.000177140869472385!GO:0043069;negative regulation of programmed cell death;0.000188198178522287!GO:0003682;chromatin binding;0.000194971329038413!GO:0031988;membrane-bound vesicle;0.000197515298819305!GO:0003714;transcription corepressor activity;0.000198895516030745!GO:0004527;exonuclease activity;0.000200829363498295!GO:0003690;double-stranded DNA binding;0.000209304355251745!GO:0005048;signal sequence binding;0.000211004791016129!GO:0005874;microtubule;0.000220953813323271!GO:0019899;enzyme binding;0.000225929928859684!GO:0043066;negative regulation of apoptosis;0.000230848080103938!GO:0030880;RNA polymerase complex;0.000235141803811136!GO:0005791;rough endoplasmic reticulum;0.000251410771150839!GO:0042981;regulation of apoptosis;0.000253535210435981!GO:0006695;cholesterol biosynthetic process;0.000261836070694249!GO:0009892;negative regulation of metabolic process;0.000262042831630653!GO:0003678;DNA helicase activity;0.000264319493623694!GO:0016023;cytoplasmic membrane-bound vesicle;0.000269136451105596!GO:0007093;mitotic cell cycle checkpoint;0.000278283703393771!GO:0005905;coated pit;0.000278477104631706!GO:0046474;glycerophospholipid biosynthetic process;0.000285505276337407!GO:0007088;regulation of mitosis;0.00029445686768002!GO:0043067;regulation of programmed cell death;0.000294983311160091!GO:0051789;response to protein stimulus;0.000303168184240268!GO:0006986;response to unfolded protein;0.000303168184240268!GO:0007052;mitotic spindle organization and biogenesis;0.000356953488771569!GO:0004576;oligosaccharyl transferase activity;0.000377797460167211!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000382549534702718!GO:0032561;guanyl ribonucleotide binding;0.000384890962891174!GO:0019001;guanyl nucleotide binding;0.000384890962891174!GO:0006612;protein targeting to membrane;0.00039215525806381!GO:0003729;mRNA binding;0.000397557900676244!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000414358376775196!GO:0008250;oligosaccharyl transferase complex;0.000417725743005508!GO:0051252;regulation of RNA metabolic process;0.000430622174261756!GO:0031982;vesicle;0.00043089066201494!GO:0005741;mitochondrial outer membrane;0.000434256234225995!GO:0007006;mitochondrial membrane organization and biogenesis;0.000434256234225995!GO:0030036;actin cytoskeleton organization and biogenesis;0.000438489253027021!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000443527797171429!GO:0005885;Arp2/3 protein complex;0.000463609618988605!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.0004738268904509!GO:0006839;mitochondrial transport;0.000473930714445654!GO:0030133;transport vesicle;0.000475624555220332!GO:0005770;late endosome;0.000505811663777467!GO:0033116;ER-Golgi intermediate compartment membrane;0.000509347250884132!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000556965122446467!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.000559490919487875!GO:0000428;DNA-directed RNA polymerase complex;0.000559490919487875!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000567802868259944!GO:0031410;cytoplasmic vesicle;0.000656955702852004!GO:0030663;COPI coated vesicle membrane;0.000675668560179801!GO:0030126;COPI vesicle coat;0.000675668560179801!GO:0006414;translational elongation;0.00068097344997677!GO:0015631;tubulin binding;0.000689155643049583!GO:0016481;negative regulation of transcription;0.000691927528823074!GO:0005684;U2-dependent spliceosome;0.000710447272819403!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000715066719503497!GO:0008186;RNA-dependent ATPase activity;0.000746590497888464!GO:0006402;mRNA catabolic process;0.000815904585365572!GO:0008610;lipid biosynthetic process;0.000886098416935213!GO:0010468;regulation of gene expression;0.000889304058764278!GO:0035258;steroid hormone receptor binding;0.000937560796090645!GO:0007017;microtubule-based process;0.000946149799012978!GO:0031072;heat shock protein binding;0.00095300664897829!GO:0000922;spindle pole;0.00095300664897829!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000970263830275889!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000977634218009519!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000977634218009519!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000977634218009519!GO:0051920;peroxiredoxin activity;0.000983913184123368!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.000994499454537282!GO:0000049;tRNA binding;0.00100843752323115!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00101171699300301!GO:0042802;identical protein binding;0.00117547967891001!GO:0005876;spindle microtubule;0.00119699745734864!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00120187765424649!GO:0051540;metal cluster binding;0.00120955316248407!GO:0051536;iron-sulfur cluster binding;0.00120955316248407!GO:0018196;peptidyl-asparagine modification;0.00126105112605832!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00126105112605832!GO:0046467;membrane lipid biosynthetic process;0.00127457005850306!GO:0030137;COPI-coated vesicle;0.00145630452194036!GO:0048500;signal recognition particle;0.00148594073120727!GO:0032508;DNA duplex unwinding;0.00149000787589275!GO:0032392;DNA geometric change;0.00149000787589275!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00152146431607025!GO:0006352;transcription initiation;0.00159797161481629!GO:0000082;G1/S transition of mitotic cell cycle;0.00161329270098552!GO:0006289;nucleotide-excision repair;0.00161740631273082!GO:0000228;nuclear chromosome;0.00164210670592847!GO:0043596;nuclear replication fork;0.00168565189390425!GO:0030029;actin filament-based process;0.00174604747756508!GO:0004004;ATP-dependent RNA helicase activity;0.00202219608538321!GO:0004518;nuclease activity;0.00203190444481992!GO:0000910;cytokinesis;0.0020706779809552!GO:0008312;7S RNA binding;0.0021011008027502!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.00210574223950245!GO:0006401;RNA catabolic process;0.0021629137245264!GO:0008139;nuclear localization sequence binding;0.00221529296351745!GO:0006275;regulation of DNA replication;0.00234108071084485!GO:0030658;transport vesicle membrane;0.00234141892626185!GO:0009112;nucleobase metabolic process;0.0024036454014181!GO:0006268;DNA unwinding during replication;0.00253025886846616!GO:0051287;NAD binding;0.0025834857357094!GO:0043284;biopolymer biosynthetic process;0.00258979798912384!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.00269699780033056!GO:0051087;chaperone binding;0.00275135747051165!GO:0003677;DNA binding;0.0029133607044196!GO:0031570;DNA integrity checkpoint;0.00307114049290738!GO:0008180;signalosome;0.00308369371838559!GO:0009116;nucleoside metabolic process;0.00310408923364965!GO:0031124;mRNA 3'-end processing;0.00312470476227872!GO:0005637;nuclear inner membrane;0.00315733956719819!GO:0030132;clathrin coat of coated pit;0.00319154722362126!GO:0031901;early endosome membrane;0.00320553713466305!GO:0043488;regulation of mRNA stability;0.00322585598645211!GO:0043487;regulation of RNA stability;0.00322585598645211!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00343748346079177!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00343748346079177!GO:0030521;androgen receptor signaling pathway;0.0035537105349997!GO:0006891;intra-Golgi vesicle-mediated transport;0.00371742446657005!GO:0030134;ER to Golgi transport vesicle;0.0037363400166454!GO:0004674;protein serine/threonine kinase activity;0.00374407767844583!GO:0046489;phosphoinositide biosynthetic process;0.00374669061074828!GO:0006595;polyamine metabolic process;0.00375595563620931!GO:0008652;amino acid biosynthetic process;0.00380752074258072!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00382484555770924!GO:0045047;protein targeting to ER;0.00382484555770924!GO:0051539;4 iron, 4 sulfur cluster binding;0.00388491739127254!GO:0016272;prefoldin complex;0.00394909677600401!GO:0050662;coenzyme binding;0.00406579327149024!GO:0006520;amino acid metabolic process;0.00407467126033842!GO:0006284;base-excision repair;0.00407467126033842!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00409286068966931!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00413046524125138!GO:0019752;carboxylic acid metabolic process;0.00415939304394084!GO:0006405;RNA export from nucleus;0.00437511326184063!GO:0006082;organic acid metabolic process;0.00439256731808079!GO:0006220;pyrimidine nucleotide metabolic process;0.0044362826939701!GO:0046483;heterocycle metabolic process;0.00466698579647561!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.00467200173383522!GO:0032774;RNA biosynthetic process;0.00483960438369533!GO:0030127;COPII vesicle coat;0.00487177125681987!GO:0012507;ER to Golgi transport vesicle membrane;0.00487177125681987!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00495451336145657!GO:0006611;protein export from nucleus;0.00497375918498002!GO:0003711;transcription elongation regulator activity;0.005014353061442!GO:0017166;vinculin binding;0.00519476503071322!GO:0048471;perinuclear region of cytoplasm;0.00528174872992038!GO:0008092;cytoskeletal protein binding;0.00539505637075085!GO:0008361;regulation of cell size;0.00540845505194691!GO:0001726;ruffle;0.00545589378472371!GO:0006144;purine base metabolic process;0.00552302018387508!GO:0030118;clathrin coat;0.0057920314995453!GO:0032984;macromolecular complex disassembly;0.00595391463992872!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.005997716986616!GO:0042770;DNA damage response, signal transduction;0.005997716986616!GO:0030041;actin filament polymerization;0.00616152839768859!GO:0006351;transcription, DNA-dependent;0.0061808720237227!GO:0004003;ATP-dependent DNA helicase activity;0.0062137763324741!GO:0016049;cell growth;0.00653313565277299!GO:0000792;heterochromatin;0.00661258933169258!GO:0043601;nuclear replisome;0.00662033658023606!GO:0030894;replisome;0.00662033658023606!GO:0030660;Golgi-associated vesicle membrane;0.00662033658023606!GO:0000178;exosome (RNase complex);0.00668645392232806!GO:0003746;translation elongation factor activity;0.00670055769304007!GO:0065007;biological regulation;0.00674351310482646!GO:0007346;regulation of progression through mitotic cell cycle;0.0068087627876889!GO:0000725;recombinational repair;0.00728001342811583!GO:0000724;double-strand break repair via homologous recombination;0.00728001342811583!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.00730787632575734!GO:0005096;GTPase activator activity;0.0073803932167962!GO:0009303;rRNA transcription;0.00770361760538683!GO:0016251;general RNA polymerase II transcription factor activity;0.00794415610209233!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.00813516145576565!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.00836965415855017!GO:0005832;chaperonin-containing T-complex;0.00838033261238833!GO:0005100;Rho GTPase activator activity;0.00838033261238833!GO:0005758;mitochondrial intermembrane space;0.00841643243572194!GO:0007050;cell cycle arrest;0.00841643243572194!GO:0043022;ribosome binding;0.00848245571450724!GO:0043624;cellular protein complex disassembly;0.00873872005693743!GO:0048487;beta-tubulin binding;0.00875249614607337!GO:0000339;RNA cap binding;0.00894845465910763!GO:0000096;sulfur amino acid metabolic process;0.00942279220556315!GO:0043241;protein complex disassembly;0.00946719048325722!GO:0030027;lamellipodium;0.00955640240907002!GO:0008047;enzyme activator activity;0.00968037293983247!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00988413248187299!GO:0019206;nucleoside kinase activity;0.0100380685807909!GO:0006270;DNA replication initiation;0.0102669617521392!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0103245666707258!GO:0016044;membrane organization and biogenesis;0.0105160432847898!GO:0032200;telomere organization and biogenesis;0.0106949338937618!GO:0000723;telomere maintenance;0.0106949338937618!GO:0000070;mitotic sister chromatid segregation;0.0109315213861824!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.0109331479930921!GO:0015399;primary active transmembrane transporter activity;0.0109331479930921!GO:0000077;DNA damage checkpoint;0.0109847469851739!GO:0031970;organelle envelope lumen;0.0109978961637162!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0110200467972176!GO:0015002;heme-copper terminal oxidase activity;0.0110200467972176!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0110200467972176!GO:0004129;cytochrome-c oxidase activity;0.0110200467972176!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0111387631958311!GO:0000819;sister chromatid segregation;0.0111963082218351!GO:0016408;C-acyltransferase activity;0.0112331409839635!GO:0008408;3'-5' exonuclease activity;0.011367341560507!GO:0008022;protein C-terminus binding;0.0114853592665263!GO:0030176;integral to endoplasmic reticulum membrane;0.0115056388686148!GO:0065009;regulation of a molecular function;0.0116016944713763!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0122778243796309!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0122779814268721!GO:0015992;proton transport;0.0122910148773199!GO:0000287;magnesium ion binding;0.0125088669006879!GO:0004532;exoribonuclease activity;0.0125310272827171!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0125310272827171!GO:0006740;NADPH regeneration;0.012546800807464!GO:0006098;pentose-phosphate shunt;0.012546800807464!GO:0031123;RNA 3'-end processing;0.012620720835976!GO:0006950;response to stress;0.012620720835976!GO:0006818;hydrogen transport;0.0127048954148435!GO:0050681;androgen receptor binding;0.0127286048466433!GO:0048037;cofactor binding;0.0129090730919306!GO:0045941;positive regulation of transcription;0.0130909208546622!GO:0009451;RNA modification;0.013358085771454!GO:0044454;nuclear chromosome part;0.0135837573152696!GO:0045449;regulation of transcription;0.0138886712472091!GO:0007021;tubulin folding;0.0139180201307752!GO:0016407;acetyltransferase activity;0.0139180201307752!GO:0005869;dynactin complex;0.0143882976052562!GO:0006378;mRNA polyadenylation;0.0149223751855878!GO:0006541;glutamine metabolic process;0.0152532604077019!GO:0044262;cellular carbohydrate metabolic process;0.0154173189856886!GO:0000209;protein polyubiquitination;0.0155035836044231!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0156348958373336!GO:0006007;glucose catabolic process;0.0158021037465185!GO:0030145;manganese ion binding;0.0158702205650569!GO:0048522;positive regulation of cellular process;0.0160324785690848!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0162935690052574!GO:0016584;nucleosome positioning;0.0166560747953852!GO:0031625;ubiquitin protein ligase binding;0.0170742942702749!GO:0005862;muscle thin filament tropomyosin;0.0172948239834382!GO:0006650;glycerophospholipid metabolic process;0.0172948239834382!GO:0030496;midbody;0.0172948239834382!GO:0042393;histone binding;0.0172948239834382!GO:0051128;regulation of cellular component organization and biogenesis;0.0172948239834382!GO:0043189;H4/H2A histone acetyltransferase complex;0.0174903211734851!GO:0000084;S phase of mitotic cell cycle;0.0177057679530054!GO:0001558;regulation of cell growth;0.0177703283807772!GO:0004177;aminopeptidase activity;0.0183489867557348!GO:0035267;NuA4 histone acetyltransferase complex;0.0185841879153254!GO:0009124;nucleoside monophosphate biosynthetic process;0.0185864677250863!GO:0009123;nucleoside monophosphate metabolic process;0.0185864677250863!GO:0030518;steroid hormone receptor signaling pathway;0.0189527315138334!GO:0016125;sterol metabolic process;0.0189722793024125!GO:0006338;chromatin remodeling;0.01921886612952!GO:0000152;nuclear ubiquitin ligase complex;0.0195791299994354!GO:0030833;regulation of actin filament polymerization;0.0200377043454399!GO:0006509;membrane protein ectodomain proteolysis;0.0206212801823664!GO:0033619;membrane protein proteolysis;0.0206212801823664!GO:0006778;porphyrin metabolic process;0.0207698398293571!GO:0033013;tetrapyrrole metabolic process;0.0207698398293571!GO:0008299;isoprenoid biosynthetic process;0.0207698398293571!GO:0046112;nucleobase biosynthetic process;0.0219487499104097!GO:0046128;purine ribonucleoside metabolic process;0.0219487499104097!GO:0042278;purine nucleoside metabolic process;0.0219487499104097!GO:0022411;cellular component disassembly;0.0221185281005115!GO:0000781;chromosome, telomeric region;0.0224605602395177!GO:0005669;transcription factor TFIID complex;0.0226059555503193!GO:0006376;mRNA splice site selection;0.0226395649374694!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0226395649374694!GO:0030508;thiol-disulfide exchange intermediate activity;0.0228111545317458!GO:0008154;actin polymerization and/or depolymerization;0.0228422161128798!GO:0005663;DNA replication factor C complex;0.0229349647106933!GO:0051053;negative regulation of DNA metabolic process;0.0231925882058922!GO:0004523;ribonuclease H activity;0.0233526841861288!GO:0006497;protein amino acid lipidation;0.0233933689267389!GO:0005773;vacuole;0.0238839368627281!GO:0045893;positive regulation of transcription, DNA-dependent;0.0245636885577071!GO:0030125;clathrin vesicle coat;0.0249031245289804!GO:0030665;clathrin coated vesicle membrane;0.0249031245289804!GO:0030032;lamellipodium biogenesis;0.0250291118027564!GO:0030119;AP-type membrane coat adaptor complex;0.0253529723999183!GO:0006607;NLS-bearing substrate import into nucleus;0.0261102459279864!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0261714397608805!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0264676022114482!GO:0010257;NADH dehydrogenase complex assembly;0.0264676022114482!GO:0033108;mitochondrial respiratory chain complex assembly;0.0264676022114482!GO:0000793;condensed chromosome;0.0267298013238294!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0267298013238294!GO:0030865;cortical cytoskeleton organization and biogenesis;0.0267298013238294!GO:0006779;porphyrin biosynthetic process;0.0270677047327224!GO:0033014;tetrapyrrole biosynthetic process;0.0270677047327224!GO:0000123;histone acetyltransferase complex;0.0271479678820756!GO:0022890;inorganic cation transmembrane transporter activity;0.0273606369884843!GO:0045892;negative regulation of transcription, DNA-dependent;0.0274129838001335!GO:0006506;GPI anchor biosynthetic process;0.0277668003103553!GO:0048146;positive regulation of fibroblast proliferation;0.0277963674744587!GO:0008017;microtubule binding;0.0280477372525182!GO:0009262;deoxyribonucleotide metabolic process;0.0280922227966954!GO:0031529;ruffle organization and biogenesis;0.0280922227966954!GO:0006118;electron transport;0.0281423231765943!GO:0016197;endosome transport;0.0281423231765943!GO:0000726;non-recombinational repair;0.0282827441857931!GO:0007004;telomere maintenance via telomerase;0.0282827441857931!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0284258438540299!GO:0004448;isocitrate dehydrogenase activity;0.0284258438540299!GO:0033673;negative regulation of kinase activity;0.0284258438540299!GO:0006469;negative regulation of protein kinase activity;0.0284258438540299!GO:0016581;NuRD complex;0.0284258438540299!GO:0008632;apoptotic program;0.0288122919564664!GO:0008287;protein serine/threonine phosphatase complex;0.0298000875138418!GO:0031371;ubiquitin conjugating enzyme complex;0.0299382692486318!GO:0000118;histone deacetylase complex;0.030501829370734!GO:0045045;secretory pathway;0.0309905868443676!GO:0051098;regulation of binding;0.031181146237083!GO:0006979;response to oxidative stress;0.0316179703215814!GO:0048144;fibroblast proliferation;0.0321709610156488!GO:0048145;regulation of fibroblast proliferation;0.0321709610156488!GO:0051320;S phase;0.0324175105087244!GO:0006400;tRNA modification;0.0325649288577677!GO:0003756;protein disulfide isomerase activity;0.0325649288577677!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0325649288577677!GO:0051348;negative regulation of transferase activity;0.0327608685448015!GO:0030911;TPR domain binding;0.0332874446723763!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0333061505843128!GO:0045039;protein import into mitochondrial inner membrane;0.0333061505843128!GO:0006505;GPI anchor metabolic process;0.0333197242551808!GO:0019783;small conjugating protein-specific protease activity;0.0334594167876222!GO:0003887;DNA-directed DNA polymerase activity;0.0334594167876222!GO:0005875;microtubule associated complex;0.0344088119086352!GO:0006892;post-Golgi vesicle-mediated transport;0.0352055832618887!GO:0006739;NADP metabolic process;0.0362218942271177!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.0362386913873745!GO:0005784;translocon complex;0.0362709908074911!GO:0006221;pyrimidine nucleotide biosynthetic process;0.0363048436745871!GO:0004843;ubiquitin-specific protease activity;0.0367912100670318!GO:0008243;plasminogen activator activity;0.036800399983146!GO:0008276;protein methyltransferase activity;0.0369600210920458!GO:0009161;ribonucleoside monophosphate metabolic process;0.0370461849132195!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.0370461849132195!GO:0030659;cytoplasmic vesicle membrane;0.0371682093645319!GO:0006984;ER-nuclear signaling pathway;0.0377937093521161!GO:0004722;protein serine/threonine phosphatase activity;0.0387898443347334!GO:0008234;cysteine-type peptidase activity;0.0388406997483526!GO:0009119;ribonucleoside metabolic process;0.0397797099564432!GO:0005881;cytoplasmic microtubule;0.0399755365493744!GO:0006360;transcription from RNA polymerase I promoter;0.0405787543606853!GO:0008097;5S rRNA binding;0.0411818861923051!GO:0016417;S-acyltransferase activity;0.0415504490756248!GO:0050178;phenylpyruvate tautomerase activity;0.0420409938569489!GO:0030131;clathrin adaptor complex;0.0424259895870872!GO:0005680;anaphase-promoting complex;0.0427411082081832!GO:0017134;fibroblast growth factor binding;0.0440868995795338!GO:0005099;Ras GTPase activator activity;0.0444471428709796!GO:0006266;DNA ligation;0.0449797899776197!GO:0009225;nucleotide-sugar metabolic process;0.0455013235048314!GO:0030503;regulation of cell redox homeostasis;0.0457284745464446!GO:0000097;sulfur amino acid biosynthetic process;0.0457284745464446!GO:0031577;spindle checkpoint;0.0461493849665546!GO:0008143;poly(A) binding;0.046283650997443!GO:0000175;3'-5'-exoribonuclease activity;0.0465859272419373!GO:0030433;ER-associated protein catabolic process;0.046759714942841!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.046759714942841!GO:0004239;methionyl aminopeptidase activity;0.0473631162624911!GO:0030384;phosphoinositide metabolic process;0.0477851559898159!GO:0007243;protein kinase cascade;0.0479984591500232!GO:0008629;induction of apoptosis by intracellular signals;0.0481631603446406!GO:0043130;ubiquitin binding;0.0482969442123251!GO:0032182;small conjugating protein binding;0.0482969442123251!GO:0003985;acetyl-CoA C-acetyltransferase activity;0.0486253262028147!GO:0042026;protein refolding;0.0491452303455414!GO:0006733;oxidoreduction coenzyme metabolic process;0.0492928633092326!GO:0016311;dephosphorylation;0.0494015290744369!GO:0042168;heme metabolic process;0.0495217854578043 | |||
|sample_id=11454 | |||
|sample_note= | |||
|sample_sex=unknown | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=skin | |||
|top_motifs=TFDP1:1.67595613984;PAX8:1.52957468842;NKX3-1:1.52211650036;GFI1:1.26125689755;E2F1..5:1.26037034626;NR3C1:0.989433927156;NFY{A,B,C}:0.969734912176;POU1F1:0.956314739142;NKX2-2,8:0.948645997771;TOPORS:0.863409971478;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.848443719654;MYB:0.842195534786;ZNF238:0.835710371665;PDX1:0.792172630582;ALX4:0.76707529735;HOXA9_MEIS1:0.757452863353;PAX3,7:0.737948671584;EN1,2:0.724934472606;GFI1B:0.723154958952;ZNF143:0.681420339247;GZF1:0.657519405889;SOX17:0.642109026414;NRF1:0.584521376513;T:0.582326872584;YY1:0.550275450567;HBP1_HMGB_SSRP1_UBTF:0.548274392951;ELK1,4_GABP{A,B1}:0.543008316039;HES1:0.54232371422;PBX1:0.535380569614;ONECUT1,2:0.531789176807;POU2F1..3:0.530729642103;SPZ1:0.529887274459;HOX{A5,B5}:0.522148767923;UFEwm:0.470432393341;FOXD3:0.463618101567;ZIC1..3:0.43686748303;RXR{A,B,G}:0.400019746213;AHR_ARNT_ARNT2:0.394111890587;NANOG{mouse}:0.380080127144;PRRX1,2:0.378771519768;XBP1:0.366522793361;XCPE1{core}:0.344591610622;MZF1:0.344167918721;PITX1..3:0.338527826877;PAX4:0.336451427635;TEAD1:0.318567368327;KLF4:0.310115052244;BACH2:0.303968751187;BREu{core}:0.301794605291;TAL1_TCF{3,4,12}:0.276322199195;PAX1,9:0.276176376378;TFAP2{A,C}:0.271191552636;NFIX:0.233687351837;AIRE:0.222694578108;NKX6-1,2:0.219129674771;LEF1_TCF7_TCF7L1,2:0.208184252049;NKX2-3_NKX2-5:0.208121100242;FOS_FOS{B,L1}_JUN{B,D}:0.200447486997;PAX5:0.189610877809;AR:0.185959021643;NR1H4:0.180111745285;FOXP1:0.178146598319;PRDM1:0.17058378757;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.168108355693;NR5A1,2:0.152657720689;TLX1..3_NFIC{dimer}:0.148121690691;TFAP4:0.146625939149;TBX4,5:0.136871269402;NKX3-2:0.130806531005;bHLH_family:0.129930846605;CREB1:0.122647677122;CEBPA,B_DDIT3:0.102670741473;MYBL2:0.099601770375;NKX2-1,4:0.0961489363831;ZBTB16:0.085591269858;CDC5L:0.081903253721;TP53:0.0791332718203;HOX{A4,D4}:0.0645289564368;GCM1,2:0.0490320575131;STAT5{A,B}:0.0457150051;HIC1:0.0435328629813;EVI1:0.0405867977815;NFE2L2:0.0399095867708;POU3F1..4:0.0397545477187;FOXL1:0.0352278166727;LHX3,4:0.0350950037743;ALX1:0.0222128317813;TEF:0.019528061077;SOX{8,9,10}:0.0172752246972;GATA4:0.00859048165708;NFE2L1:0.00620360277469;HLF:0.00332701553886;SRF:-0.00510209697104;TFAP2B:-0.00562373423941;CRX:-0.0156575287286;CDX1,2,4:-0.019110834766;GTF2I:-0.0287078963057;ELF1,2,4:-0.0311271575403;NANOG:-0.0387152231652;ESR1:-0.0420796113886;FOSL2:-0.0539508392749;STAT1,3:-0.0704702340037;HNF1A:-0.0806488397988;HIF1A:-0.0825895524006;RXRA_VDR{dimer}:-0.0842456339039;TGIF1:-0.08647389092;NFATC1..3:-0.0987524864028;HNF4A_NR2F1,2:-0.104671315492;ATF6:-0.105376596928;IKZF1:-0.12286943148;IKZF2:-0.123748885736;ZFP161:-0.126566878463;FOXQ1:-0.147191870694;NFE2:-0.149162096347;VSX1,2:-0.153807953071;GTF2A1,2:-0.158682318123;SOX5:-0.162086279596;NR6A1:-0.164430655922;FOX{I1,J2}:-0.179739096432;HSF1,2:-0.189661807421;ZBTB6:-0.207081238588;DBP:-0.210074169771;MTF1:-0.238923961135;PATZ1:-0.239542948555;HOX{A6,A7,B6,B7}:-0.240247046289;RFX1:-0.254022300936;TBP:-0.254181724434;FOXA2:-0.255126144534;RFX2..5_RFXANK_RFXAP:-0.272206668643;POU5F1:-0.293227319276;RUNX1..3:-0.295836290275;MEF2{A,B,C,D}:-0.310581609822;TFCP2:-0.313933518883;ATF4:-0.317982215651;OCT4_SOX2{dimer}:-0.318115532225;SP1:-0.324046624919;NFKB1_REL_RELA:-0.329899606223;MED-1{core}:-0.337579896277;ARID5B:-0.340710911285;ESRRA:-0.344124435043;HAND1,2:-0.345014386414;SPI1:-0.348146370654;GATA6:-0.349214122623;ZNF384:-0.353315181513;DMAP1_NCOR{1,2}_SMARC:-0.366101072889;FOXM1:-0.384346910752;REST:-0.384917352692;ATF5_CREB3:-0.398347145734;EGR1..3:-0.403973340842;MTE{core}:-0.408874346677;NHLH1,2:-0.44698601003;MYFfamily:-0.471724613346;POU6F1:-0.479805279043;STAT2,4,6:-0.481144585739;MAZ:-0.483317563784;SOX2:-0.490892871926;JUN:-0.4928227733;ATF2:-0.499233146332;RREB1:-0.506068393302;ADNP_IRX_SIX_ZHX:-0.506346912117;SPIB:-0.508138238748;GLI1..3:-0.510132762711;CUX2:-0.51346621633;PPARG:-0.519033138202;PAX2:-0.523060186011;ETS1,2:-0.52525855483;ZNF423:-0.562761491839;EBF1:-0.563749639814;ZNF148:-0.587840840186;BPTF:-0.607276626056;MAFB:-0.608721423021;FOXO1,3,4:-0.647267734395;FOX{F1,F2,J1}:-0.694506320343;HMGA1,2:-0.695818156789;SMAD1..7,9:-0.704743582173;EP300:-0.713722242241;RBPJ:-0.757716736918;SNAI1..3:-0.758394277942;HMX1:-0.764299589795;FOXN1:-0.772269338774;IRF7:-0.776045695487;PAX6:-0.820834342268;IRF1,2:-0.858162864979;MYOD1:-0.874294329367;NFIL3:-0.890267151939;FOXP3:-0.894624653839;ZEB1:-0.9061851099;LMO2:-0.952043320263;RORA:-0.978261796982;SREBF1,2:-1.04213168879;FOX{D1,D2}:-1.12688877085;TLX2:-1.48108567146 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11454-119A5;search_select_hide=table117:FF:11454-119A5 | |||
}} | }} |
Latest revision as of 18:02, 4 June 2020
Name: | Fibroblast - Dermal, donor5 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs12055 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12055
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12055
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.716 |
10 | 10 | 0.178 |
100 | 100 | 0.573 |
101 | 101 | 0.608 |
102 | 102 | 0.445 |
103 | 103 | 0.0276 |
104 | 104 | 0.792 |
105 | 105 | 0.575 |
106 | 106 | 0.00355 |
107 | 107 | 0.194 |
108 | 108 | 0.225 |
109 | 109 | 0.888 |
11 | 11 | 0.973 |
110 | 110 | 0.421 |
111 | 111 | 0.948 |
112 | 112 | 0.0535 |
113 | 113 | 0.0106 |
114 | 114 | 0.228 |
115 | 115 | 0.866 |
116 | 116 | 0.389 |
117 | 117 | 0.8 |
118 | 118 | 0.683 |
119 | 119 | 0.0973 |
12 | 12 | 0.512 |
120 | 120 | 0.178 |
121 | 121 | 0.655 |
122 | 122 | 0.119 |
123 | 123 | 0.402 |
124 | 124 | 0.156 |
125 | 125 | 0.654 |
126 | 126 | 0.841 |
127 | 127 | 0.605 |
128 | 128 | 0.0322 |
129 | 129 | 0.0943 |
13 | 13 | 0.937 |
130 | 130 | 0.00733 |
131 | 131 | 0.53 |
132 | 132 | 0.865 |
133 | 133 | 0.989 |
134 | 134 | 0.517 |
135 | 135 | 0.0492 |
136 | 136 | 0.237 |
137 | 137 | 0.0455 |
138 | 138 | 0.0972 |
139 | 139 | 3.41692e-5 |
14 | 14 | 0.0827 |
140 | 140 | 0.8 |
141 | 141 | 0.791 |
142 | 142 | 0.541 |
143 | 143 | 0.59 |
144 | 144 | 0.519 |
145 | 145 | 0.425 |
146 | 146 | 0.707 |
147 | 147 | 0.457 |
148 | 148 | 0.412 |
149 | 149 | 0.236 |
15 | 15 | 0.264 |
150 | 150 | 0.79 |
151 | 151 | 0.207 |
152 | 152 | 0.13 |
153 | 153 | 0.47 |
154 | 154 | 0.457 |
155 | 155 | 0.0536 |
156 | 156 | 0.547 |
157 | 157 | 0.0976 |
158 | 158 | 0.0288 |
159 | 159 | 0.0319 |
16 | 16 | 0.635 |
160 | 160 | 0.479 |
161 | 161 | 0.879 |
162 | 162 | 0.677 |
163 | 163 | 0.563 |
164 | 164 | 0.773 |
165 | 165 | 0.138 |
166 | 166 | 0.958 |
167 | 167 | 0.643 |
168 | 168 | 0.48 |
169 | 169 | 0.0911 |
17 | 17 | 0.404 |
18 | 18 | 0.686 |
19 | 19 | 0.777 |
2 | 2 | 0.51 |
20 | 20 | 0.196 |
21 | 21 | 0.137 |
22 | 22 | 0.268 |
23 | 23 | 0.036 |
24 | 24 | 0.656 |
25 | 25 | 0.775 |
26 | 26 | 0.328 |
27 | 27 | 0.521 |
28 | 28 | 0.334 |
29 | 29 | 0.916 |
3 | 3 | 0.722 |
30 | 30 | 0.403 |
31 | 31 | 0.451 |
32 | 32 | 0.816 |
33 | 33 | 0.478 |
34 | 34 | 0.327 |
35 | 35 | 0.477 |
36 | 36 | 0.664 |
37 | 37 | 0.545 |
38 | 38 | 0.345 |
39 | 39 | 0.725 |
4 | 4 | 0.11 |
40 | 40 | 0.48 |
41 | 41 | 0.256 |
42 | 42 | 0.865 |
43 | 43 | 0.22 |
44 | 44 | 0.628 |
45 | 45 | 0.045 |
46 | 46 | 0.486 |
47 | 47 | 0.954 |
48 | 48 | 0.618 |
49 | 49 | 0.263 |
5 | 5 | 0.122 |
50 | 50 | 0.571 |
51 | 51 | 0.61 |
52 | 52 | 0.186 |
53 | 53 | 0.341 |
54 | 54 | 0.608 |
55 | 55 | 0.737 |
56 | 56 | 0.764 |
57 | 57 | 0.778 |
58 | 58 | 0.131 |
59 | 59 | 0.378 |
6 | 6 | 0.697 |
60 | 60 | 0.0331 |
61 | 61 | 0.989 |
62 | 62 | 0.243 |
63 | 63 | 0.975 |
64 | 64 | 0.708 |
65 | 65 | 0.155 |
66 | 66 | 0.0758 |
67 | 67 | 0.791 |
68 | 68 | 0.707 |
69 | 69 | 0.663 |
7 | 7 | 0.424 |
70 | 70 | 0.00671 |
71 | 71 | 0.983 |
72 | 72 | 0.176 |
73 | 73 | 0.501 |
74 | 74 | 0.225 |
75 | 75 | 0.473 |
76 | 76 | 0.955 |
77 | 77 | 0.777 |
78 | 78 | 0.71 |
79 | 79 | 0.696 |
8 | 8 | 0.81 |
80 | 80 | 0.0634 |
81 | 81 | 0.375 |
82 | 82 | 0.0081 |
83 | 83 | 0.213 |
84 | 84 | 0.967 |
85 | 85 | 0.013 |
86 | 86 | 0.464 |
87 | 87 | 0.129 |
88 | 88 | 0.322 |
89 | 89 | 0.169 |
9 | 9 | 0.692 |
90 | 90 | 0.627 |
91 | 91 | 0.46 |
92 | 92 | 0.252 |
93 | 93 | 0.724 |
94 | 94 | 0.951 |
95 | 95 | 0.242 |
96 | 96 | 0.303 |
97 | 97 | 0.88 |
98 | 98 | 0.225 |
99 | 99 | 0.0632 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs12055
FANTOM5 (FF) ontology
Direct parent terms
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0002320 (connective tissue cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
0000057 (fibroblast)
0002620 (skin fibroblast)
0002551 (fibroblast of dermis)
UBERON: Anatomy
0000468 (multi-cellular organism)
0002097 (skin of body)
0002199 (integument)
0002384 (connective tissue)
0000479 (tissue)
0000064 (organ part)
0010314 (structure with developmental contribution from neural crest)
0000062 (organ)
0004120 (mesoderm-derived structure)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0004923 (organ component layer)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0003102 (surface structure)
0010317 (germ layer / neural crest derived structure)
0002067 (dermis)
0002416 (integumental system)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000057 (fibroblast sample)
0000250 (human fibroblast of skin sample)
0000001 (sample)
0000062 (human dermal fibroblast sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)