FF:11782-124A9: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005031 | ||
| | |accession_numbers=CAGE;DRX008184;DRR009056;DRZ000481;DRZ001866;DRZ011831;DRZ013216 | ||
| | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0002371,CL:0000542,CL:0000219,CL:0000738,CL:0002087,CL:0002242,CL:0000255,CL:0000791,CL:0000084,CL:0000789,CL:0002419,CL:0000624,CL:0000815,CL:0000898,CL:0000792,CL:0002677 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001 | ||
|comment=Previously: CD4-positiveCD25-positiveCD45RA- naive regulatory T cells, donor1. TODO: full classification | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chrX:49121165..49121179,-!p1@FOXP3!2.37!234.21!FOXP3;;chr6:106546808..106546833,+!p3@PRDM1!1.98!119.02!PRDM1;;chr10:35484053..35484076,+!p1@CREM!1.96!215.65!CREM;;chr3:63953435..63953499,+!p1@ATXN7!1.85!70.12!ATXN7;;chr1:25256756..25256774,-!p1@RUNX3!1.82!118.73!RUNX3;;chr10:8096631..8096660,+!p1@GATA3!1.76!68.05!GATA3;;chrX:106960285..106960299,-!p1@TSC22D3!1.71!1260.62!TSC22D3;;chr3:71355163..71355209,-!p5@FOXP1!1.71!69.23!FOXP1;;chr19:54058073..54058088,+!p1@ZNF331!1.71!50.08!ZNF331;;chr19:54041669..54041697,+!p2@ZNF331!1.70!49.49!ZNF331;;chr10:35484090..35484104,+!p6@CREM!1.70!48.61!CREM;;chr6:106546834..106546850,+!p4@PRDM1!1.67!46.25!PRDM1;;chr2:231090433..231090469,+!p1@SP140!1.66!44.19!SP140;;chr7:50343634..50343717,+!p2@IKZF1!1.65!43.90!IKZF1;;chr4:109087445..109087463,-!p1@LEF1!1.62!40.66!LEF1;;chr15:60884706..60884743,-!p1@RORA!1.59!187.37!RORA;;chr6:391743..391759,+!p1@IRF4!1.59!38.30!IRF4;;chr14:75988771..75988826,+!p1@BATF!1.55!45.66!BATF;;chr19:16435625..16435682,+!p1@KLF2!1.54!1022.87!KLF2;;chrY:21906594..21906622,-!p1@KDM5D!1.54!33.29!KDM5D;;chr2:157189180..157189290,-!p1@NR4A2!1.53!166.45!NR4A2;;chr17:37934365..37934387,-!p2@IKZF3!1.49!30.05!IKZF3;;chr8:60031619..60031676,-!p1@TOX!1.48!61.87!TOX;;chr14:75988831..75988847,+!p2@BATF!1.48!28.87!BATF;;chr10:35416142..35416169,+!p3@CREM!1.43!67.46!CREM;;chr2:192015701..192015743,-!p1@STAT4!1.43!35.35!STAT4;;chr20:56195474..56195506,-!p1@ZBP1!1.40!24.16!ZBP1;;chr2:192015750..192015793,-!p2@STAT4!1.39!31.23!STAT4;;chr19:19779619..19779670,+!p1@ZNF101!1.38!63.93!ZNF101;;chr9:117150254..117150271,-!p1@AKNA!1.37!59.51!AKNA;;chr9:102584262..102584276,+!p1@NR4A3!1.37!49.20!NR4A3;;chr2:231090471..231090504,+!p2@SP140!1.35!21.21!SP140;;chr19:12902289..12902307,+!p1@JUNB!1.33!4465.64!JUNB;;chr6:106546786..106546802,+!p6@PRDM1!1.33!20.33!PRDM1;;chr4:109089901..109089930,-!p3@LEF1!1.30!18.85!LEF1;;chr19:19729477..19729542,-!p1@PBX4!1.25!35.35!PBX4;;chr17:37934204..37934241,-!p3@IKZF3!1.25!16.79!IKZF3;;chr4:109090075..109090095,-!p2@LEF1!1.25!16.79!LEF1;;chr9:3525727..3525828,-!p2@RFX3!1.24!41.83!RFX3;;chr3:71542615..71542644,-!p12@FOXP1!1.24!16.20!FOXP1;;chr7:50343895..50343936,+!p5@IKZF1!1.24!16.20!IKZF1;;chr6:12009042..12009092,+!p6@HIVEP1!1.23!20.92!HIVEP1;;chr11:128392273..128392308,-!p2@ETS1!1.22!64.81!ETS1;;chr6:91006518..91006570,-!p1@BACH2!1.21!35.06!BACH2;;chr10:8096772..8096787,+!p2@GATA3!1.21!17.97!GATA3;;chr13:41593425..41593480,-!p1@ELF1!1.20!92.21!ELF1;;chr4:109088089..109088101,-!p11@LEF1!1.20!15.02!LEF1;;chr19:36204309..36204335,+!p1@ZBTB32!1.19!14.44!ZBTB32;;chr17:38497662..38497713,+!p4@RARA!1.17!16.20!RARA;;chr20:56195525..56195556,-!p2@ZBP1!1.16!13.55!ZBP1;;chr11:128392085..128392232,-!p1@ETS1!1.14!424.82!ETS1;;chr20:50159198..50159299,-!p1@NFATC2!1.14!18.56!NFATC2;;chr14:99738138..99738163,-!p1@BCL11B!1.14!12.96!BCL11B;;chr2:97202991..97203043,+!p3@ARID5A!1.14!12.67!ARID5A;;chr6:106546731..106546755,+!p5@PRDM1!1.14!12.67!PRDM1;;chr1:45805693..45805718,+!p3@TOE1!1.13!26.81!TOE1;;chr10:35485013..35485034,+!p15@CREM!1.12!12.08!CREM;;chr2:214015343..214015366,-!p3@IKZF2!1.12!12.08!IKZF2;;chr21:36421535..36421610,-!p2@RUNX1!1.11!42.72!RUNX1;;chr9:102584241..102584261,+!p4@NR4A3!1.11!18.56!NR4A3;;chr19:45971246..45971265,+!p1@FOSB!1.10!216.24!FOSB;;chr5:133450365..133450444,+!p1@TCF7!1.09!51.85!TCF7;;chr4:109088130..109088163,-!p13@LEF1!1.09!11.20!LEF1;;chr11:128563948..128564003,+!p1@FLI1!1.08!134.63!FLI1;;chr14:75745523..75745537,+!p1@FOS!1.06!1270.34!FOS;;chrX:106960180..106960197,-!p2@TSC22D3!1.06!40.66!TSC22D3;;chr7:50344251..50344288,+!p3@IKZF1!1.06!10.61!IKZF1;;chr12:72056800..72056834,+!p1@THAP2!1.05!13.85!THAP2;;chr10:35416223..35416234,+!p12@CREM!1.05!10.31!CREM;;chr7:77428066..77428132,+!p2@PHTF2!1.04!65.40!PHTF2;;chr2:208394817..208394834,+!p3@CREB1!1.04!40.66!CREB1;;chr16:79634624..79634642,-!p1@MAF!1.04!39.48!MAF;;chr4:109088940..109089037,-!p4@LEF1!1.04!10.02!LEF1;;chr10:35416172..35416184,+!p13@CREM!1.04!10.02!CREM;;chr4:38665769..38665801,+!p2@KLF3!1.03!88.97!KLF3;;chr13:41240717..41240735,-!p2@FOXO1!1.03!66.58!FOXO1;;chr3:23986824..23986848,+!p2@NR1D2!1.02!53.91!NR1D2;;chr14:64971288..64971316,-!p2@ZBTB25!1.02!29.46!ZBTB25;;chr14:64970670..64970712,-!p3@ZBTB25!1.02!20.92!ZBTB25;;chr16:79634595..79634620,-!p2@MAF!1.02!17.38!MAF;;chr10:3824332..3824425,-!p4@KLF6!1.02!15.61!KLF6;;chr3:71542684..71542720,-!p18@FOXP1!1.02!9.43!FOXP1;;chr2:157189617..157189667,-!p4@NR4A2!1.01!9.13!NR4A2;;chr2:97202480..97202499,+!p1@ARID5A!1.00!93.98!ARID5A;;chr19:19779686..19779697,+!p3@ZNF101!0.99!10.31!ZNF101;;chr17:37934280..37934299,-!p6@IKZF3!0.99!8.84!IKZF3;;chr8:60031563..60031574,-!p7@TOX!0.99!8.84!TOX;;chr15:60884747..60884774,-!p3@RORA!0.98!21.51!RORA;;chrX:106960221..106960236,-!p3@TSC22D3!0.97!23.86!TSC22D3;;chr17:56565257..56565283,-!p2@HSF5!0.97!8.25!HSF5;;chr19:54040550..54040594,+!p20@ZNF331!0.97!8.25!ZNF331;;chr10:63809013..63809041,+!p3@ARID5B!0.95!45.66!ARID5B;;chr12:56418637..56418648,+!p9@IKZF4!0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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000084;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000542;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000624;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000789;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000893;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988 | |||
|ffid_belonging_in_development=CL:0000134,CL:0000051,CL:0000790 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 41: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|top_motifs= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD4%252bCD25%252bCD45RA-%2520memory%2520regulatory%2520T%2520cells%252c%2520donor1.CNhs13195.11782-124A9.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD4%252bCD25%252bCD45RA-%2520memory%2520regulatory%2520T%2520cells%252c%2520donor1.CNhs13195.11782-124A9.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD4%252bCD25%252bCD45RA-%2520memory%2520regulatory%2520T%2520cells%252c%2520donor1.CNhs13195.11782-124A9.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD4%252bCD25%252bCD45RA-%2520memory%2520regulatory%2520T%2520cells%252c%2520donor1.CNhs13195.11782-124A9.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD4%252bCD25%252bCD45RA-%2520memory%2520regulatory%2520T%2520cells%252c%2520donor1.CNhs13195.11782-124A9.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11782-124A9 | |||
|is_a=CL:0002677;;EFO:0002091;;FF:0000002;;FF:0000210 | |||
|is_obsolete= | |||
|library_id=CNhs13195 | |||
|library_id_phase_based=2:CNhs13195 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11782 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11782 | |||
|name=CD4+CD25+CD45RA- memory regulatory T cells, donor1 | |||
|namespace= | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs13195,LSID1004,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,0.114720848213924,0,0.0210592321583407,0.160155358345493,0,0,0,0.338142339257007,0,0,0,0,0,0,0.112137584435249,0.112137584435249,0,0.28878587358757,0,0,0,0,0.442108883935998,0.0141796881671911,0,0,0.205185749478145,0,0,0,0,0,0,0,0,0,0,0,0,0.233485606747132,0.112137584435249,0,0,0,0,0,0,0,0.0763758714597665,0,0,0,0,0,-0.0839305477320758,0,0.104189423902596,0,0,0.240798712043911,0,0,0,0,0,0,0,0,0,0,1.13570668662931,0,0,0.338142339257007,0,0,0,0,0,0,0,0,0,-0.0500172966961276,-0.287381167918175,0,0,0,-0.313449753257096,0.333001255141641,0,0,0.419176356909372,0,0.344073532698292,0.0305939688276086,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0403048017048366,0.112137584435249,0,0,0.0965717504702746,0.169849795750658,0,0,0,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0.27503887830031,0.344073532698292,0,0,0.27503887830031,0,0,0,0,0,0,0,0,-0.247178875285564,0,-0.199047340451698,-0.143515142523472,0.0560687922176245,0.112137584435249,-0.315141502474322,0,0,0,0,0.525931580826295,0,0.799540853263707,0.596163582600206,0,-0.128119866952565,0,-0.0504125515893149,0,0.27503887830031,0.112137584435249,0,0,-0.0304333525980971,0,-0.118189268931885,-0.0683442610773682,0,0,0,0,-0.132721230184169,0,0.217262855463267,-0.0827201683234173,0,-0.565858152667559,0.154377126252821,0,0,0,-0.355614457549934,-0.625149609873478,0,0,0.074834800007831,0.208026201506442,0,0,-0.391044581551635,0,-0.273938119603866,-0.248868050382253,0,-0.127660894080525,0,0,0.201181785145201,0,0,0,0,0,0,0,0,-0.0574934668214365,0.159050820203095,0,0,0,-0.0739148182245154,0.0796780687793939,0,-0.0138323107379372,-0.261148571521318,-0.347769903231315,0.0358642819943762,-0.64915630234649,0,-0.302389727009913,-0.360425934604194,-0.616475650718982,-0.121156291450853,-0.147401849371139,-0.189981719549847,-0.0701559309764258,-0.205270049091201,-0.102336576414342,-0.11998956705525,0.0486743751356284,-0.105606234499199,-1.2314085082871,-0.0841076844514408,0,0,-0.0775089264793031,0.655407807974244,0,0,-0.215075836176463,-0.252016174501844,-0.67098743647571,-0.5531993676716,-0.495159425089605,-0.0333428954487831,-0.0395325284566706,-0.0153275689605968,-0.0462621616141911,-0.4215723249037,0,0,-0.072522651866548,-0.128367040866231,-0.510873228807012,0.604650989305048,-0.0583007983101719,-0.371839877375732,-0.0683442610773682,0,-0.962426185069684,-0.0980311078820484,0,-0.0128901248738142,-0.0927378139893482,0.442108883935998,0,0,0,0,-0.0500172966961276,0.688618563874313,0.797420036648609,0,-0.0981314198297495,-0.0632244178678062,0.367187026947566,0,0.161784074305582,0,0,-0.198403764142742,0,-0.293169124302928,-0.495480083802912,-0.164990696339003,0.140070929456987,-0.0584468268118252,0.376202855603488,0.0911602015133814,-0.313449753257096,-0.0320228475043796,-0.104636221884863,-0.0881268324752877,0,-0.287381167918175,0.326230616082183,-0.291676930643111,-0.114777136866303,0,0.287654279085817,0,0.139339396087204,0,0.39812318581691,0.116169480912406,1.01400372358585,-0.030117115038834,0,-0.00623696427331111,-0.788130937773974,0,-0.135723143846782,-0.0239080794114359,0,-0.150367083334639,-0.697695966512583,-0.0180621964968098,-0.138989456679195,0,-0.677942573954408,0,0,-0.226077895162789,0.102666301492619,0,0.0368815426760794,-0.0467371793646719,-0.162107157259297,0.277258230084476,0.27503887830031,0,-0.645700337992725,0,0,-0.493790479382782,-0.13898373679703,-0.344744445658323,0.139902962032655,-0.10823366771846,-0.108622809454255,0,0,0.0975111123351345,1.11656930013524,-0.211143005198519,0,0,-0.137743712163575,-0.116628112990133,0,0.112137584435249,0,-0.13919689834014,0,0.112137584435249,0,0,0.051459118000036,0,0,0.156842637206387,-0.153651545071247,0,-0.105031656877146,0,0,0,0,0,0.208736224040663,0,0,-0.334960875414881,-0.0174104828800794,-0.0108798312411716,0,0,0,0,-0.215723402553475,0.0718023162055864,0.112137584435249,0.0693190786475697,0,0,0.112137584435249,0,-0.0861409897892114,0,0,0,0.1005908925726,0.217308421246646,0.109311736051183,0,0,0,0.0611879376552171,0,0,0,0,0.230256158603243,0,0,-0.519792588951131,0,-0.115105887362621,0.193456998753469,0,0.45993338848724,0.0612047732994903,-1.30962034064846,0,0,-0.261347131789888,0,0,0.090299075441002,0,0,0,0,0,0.0560687922176245,0,0,0.838352713818745,0.38184907020045,0,0,0,0,0,0,0,0,0,0,0,0.19305627567119,-0.0922240566585104,0,0,0,0,0,0,0,-0.0241060230789031,-0.106168881246201,0.1005908925726,0,0,0,0,0,0,0,-0.196387061362932,0,0,0.201181785145201,0,0,0.104189423902596,0,0,0,0,0.119128931545786,0,0,-0.00232325389320381,0,0,0,0,0,0,0,0,0,0,0,0,0,0.472844496564758,0.0210592321583407,0,0,0,0,0,0,0,0.287632436642634,0,0.201181785145201,0,0,1.97590365908968,0,0,0,-0.104796384789156,0,0.114720848213924,0,0.112137584435249,0,0,0,0,0.137519439150155,0.137519439150155,0,0,0,0,0,0,0,0,0,0.243019708441032,0,0,0,-0.550764628905838,-0.0247755787802223,-0.0901308784340158,0.0188020497278303,0,0,-0.232628352633041,0,0,0,0,0,0,0.0247283681890972,0,0,0,0,0,0,0.0560687922176245,0,0.281232867424362,0.112137584435249,0,0,0,0,0,0,0,0.27503887830031,0.112137584435249,0,0,0,0,0,0,-0.0348580438050884,0,0,0,0,0,0,0,0.0141796881671911,0,0,0.502917039630767,0,0,0,0,0,0,-0.187385948084108,-0.283220399823148,-0.138568527238287,0,0,0,-0.054385572482455,0,0,-0.0610664296457979,0,0.0453601970163473,0,0,0,0,0,0,0,0,0,0,0,0,1.12890305272791,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.28878587358757,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.33413409090986,0,0,0,0,0,0,0,0,0.112137584435249,0.156659684790225,0,0,0,0,0,0,0.066579529297184,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.195020410031672,0,0,0,-0.100948645221795,0,0,0,0,0,0,0.112137584435249,0,0.112137584435249,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.112137584435249,0,0.304221164756753,0,0,0,0,0,0,0,0,0,0,0,0,0,0.15295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| |||
|rna_box=124 | |||
|rna_catalog_number= | |||
|rna_concentration=0.12538 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number=2 | |||
|rna_od260/230=1.71 | |||
|rna_od260/280=1.95 | |||
|rna_position=A9 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=124A9 | |||
|rna_weight_ug=1.2538 | |||
|sample_age=25 | |||
|sample_category=primary cells | |||
|sample_cell_catalog= | |||
|sample_cell_line= | |||
|sample_cell_lot= | |||
|sample_cell_type=T cell | |||
|sample_collaboration=Michael Rehli (University of Regensberg) | |||
|sample_company= | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease= | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;3.07981414210995e-231!GO:0043227;membrane-bound organelle;3.47531153828682e-199!GO:0043231;intracellular membrane-bound organelle;7.78692614394997e-199!GO:0043226;organelle;3.80307666186198e-188!GO:0043229;intracellular organelle;2.04747932432757e-187!GO:0005737;cytoplasm;1.02958776541e-136!GO:0044422;organelle part;1.61927835776317e-117!GO:0044446;intracellular organelle part;6.78037794421879e-116!GO:0005634;nucleus;4.50513201778737e-106!GO:0044237;cellular metabolic process;1.58065118839636e-101!GO:0043170;macromolecule metabolic process;1.1218785829369e-100!GO:0032991;macromolecular complex;5.65722428791953e-100!GO:0044238;primary metabolic process;6.65384315822556e-97!GO:0044444;cytoplasmic part;8.18332038879753e-94!GO:0030529;ribonucleoprotein complex;3.30688997809944e-89!GO:0003723;RNA binding;2.73342840667248e-80!GO:0044428;nuclear part;4.3147400325915e-76!GO:0043283;biopolymer metabolic process;8.79913447476997e-72!GO:0043233;organelle lumen;5.14801796424163e-65!GO:0031974;membrane-enclosed lumen;5.14801796424163e-65!GO:0010467;gene expression;3.00082580160226e-61!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.29893446160971e-57!GO:0005739;mitochondrion;1.30275759679569e-56!GO:0006396;RNA processing;1.2107101707806e-55!GO:0005515;protein binding;3.28624995009681e-53!GO:0006412;translation;1.85537311221434e-52!GO:0043234;protein complex;2.44934159927948e-49!GO:0019538;protein metabolic process;2.76504143912157e-49!GO:0005840;ribosome;4.98234936714268e-49!GO:0016071;mRNA metabolic process;1.18998147449267e-47!GO:0044267;cellular protein metabolic process;1.32643886904229e-47!GO:0031981;nuclear lumen;9.81438623858131e-47!GO:0044260;cellular macromolecule metabolic process;1.58433978792572e-46!GO:0033036;macromolecule localization;1.63129391152564e-44!GO:0003735;structural constituent of ribosome;1.60178787315381e-43!GO:0003676;nucleic acid binding;3.27376243535837e-43!GO:0015031;protein transport;6.32278644493942e-43!GO:0045184;establishment of protein localization;2.62498542334435e-41!GO:0008380;RNA splicing;3.71770825736201e-41!GO:0006397;mRNA processing;4.24484384525437e-41!GO:0008104;protein localization;5.55232593739765e-41!GO:0009059;macromolecule biosynthetic process;1.48252242191997e-40!GO:0044429;mitochondrial part;7.07940655881878e-40!GO:0033279;ribosomal subunit;1.22861790029824e-38!GO:0031090;organelle membrane;1.0278261302966e-37!GO:0031967;organelle envelope;2.70178189836171e-37!GO:0031975;envelope;5.89907524819685e-37!GO:0005829;cytosol;5.30027364216926e-35!GO:0016070;RNA metabolic process;2.29880224925393e-33!GO:0006259;DNA metabolic process;5.67512143853521e-33!GO:0009058;biosynthetic process;5.93651930083509e-32!GO:0044249;cellular biosynthetic process;6.15505475862427e-32!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.81537705096886e-31!GO:0005681;spliceosome;2.60610622122493e-31!GO:0046907;intracellular transport;6.32404798214614e-31!GO:0005830;cytosolic ribosome (sensu Eukaryota);9.12302808117149e-31!GO:0005654;nucleoplasm;1.39811678742406e-29!GO:0006886;intracellular protein transport;1.47812327002094e-29!GO:0065003;macromolecular complex assembly;1.65457113994286e-29!GO:0016043;cellular component organization and biogenesis;2.00038579168239e-28!GO:0044445;cytosolic part;5.66162384007385e-28!GO:0006512;ubiquitin cycle;2.22307306524408e-26!GO:0022607;cellular component assembly;8.06791253201877e-26!GO:0005740;mitochondrial envelope;8.29533713157373e-26!GO:0000166;nucleotide binding;2.0608688776039e-25!GO:0031966;mitochondrial membrane;5.91172373847969e-25!GO:0019866;organelle inner membrane;1.10178823029189e-24!GO:0006996;organelle organization and biogenesis;1.23784447019676e-24!GO:0044451;nucleoplasm part;9.29970049359893e-24!GO:0005743;mitochondrial inner membrane;4.05328875455486e-22!GO:0051641;cellular localization;2.52820270199399e-21!GO:0051649;establishment of cellular localization;3.66566035633613e-21!GO:0006119;oxidative phosphorylation;1.40940178673736e-20!GO:0022618;protein-RNA complex assembly;1.67431281226543e-20!GO:0043412;biopolymer modification;1.68573500106757e-20!GO:0043228;non-membrane-bound organelle;3.22723196418256e-20!GO:0043232;intracellular non-membrane-bound organelle;3.22723196418256e-20!GO:0012501;programmed cell death;3.22969677501168e-20!GO:0006915;apoptosis;3.22969677501168e-20!GO:0044265;cellular macromolecule catabolic process;6.11733331809581e-20!GO:0015935;small ribosomal subunit;6.59143413963632e-20!GO:0015934;large ribosomal subunit;1.00925978650018e-19!GO:0016874;ligase activity;1.05956596519412e-19!GO:0008219;cell death;1.65949818067088e-19!GO:0016265;death;1.65949818067088e-19!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;2.88988040164811e-19!GO:0016462;pyrophosphatase activity;3.16228567929906e-19!GO:0017111;nucleoside-triphosphatase activity;3.33802339603585e-19!GO:0016817;hydrolase activity, acting on acid anhydrides;3.67108697821491e-19!GO:0044455;mitochondrial membrane part;4.79182449815381e-19!GO:0019941;modification-dependent protein catabolic process;1.24564488806885e-18!GO:0043632;modification-dependent macromolecule catabolic process;1.24564488806885e-18!GO:0051603;proteolysis involved in cellular protein catabolic process;1.42399978360347e-18!GO:0006511;ubiquitin-dependent protein catabolic process;3.00898612908722e-18!GO:0044257;cellular protein catabolic process;3.03375813688606e-18!GO:0006464;protein modification process;4.62425146966727e-18!GO:0005730;nucleolus;6.24644845068719e-18!GO:0032553;ribonucleotide binding;6.54307582007326e-18!GO:0032555;purine ribonucleotide binding;6.54307582007326e-18!GO:0043285;biopolymer catabolic process;7.26234301022894e-18!GO:0006974;response to DNA damage stimulus;7.9813974856736e-18!GO:0008134;transcription factor binding;2.28153619956176e-17!GO:0017076;purine nucleotide binding;2.85442766102687e-17!GO:0008135;translation factor activity, nucleic acid binding;4.53846417819268e-17!GO:0031980;mitochondrial lumen;5.8103340900235e-17!GO:0005759;mitochondrial matrix;5.8103340900235e-17!GO:0051276;chromosome organization and biogenesis;6.74161310573817e-17!GO:0006605;protein targeting;7.40626585013181e-17!GO:0006325;establishment and/or maintenance of chromatin architecture;1.37743695525568e-16!GO:0043687;post-translational protein modification;1.7283141914464e-16!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);2.07124746044912e-16!GO:0009057;macromolecule catabolic process;3.76627948196356e-16!GO:0016604;nuclear body;3.79032586661315e-16!GO:0006323;DNA packaging;6.34151581823528e-16!GO:0005746;mitochondrial respiratory chain;9.59925984308248e-16!GO:0006281;DNA repair;1.0795292684832e-15!GO:0005524;ATP binding;1.1052232174702e-15!GO:0007049;cell cycle;2.28850238483621e-15!GO:0000502;proteasome complex (sensu Eukaryota);2.43134277027544e-15!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);3.0948937096777e-15!GO:0016887;ATPase activity;3.93880929765975e-15!GO:0032559;adenyl ribonucleotide binding;4.60060689828841e-15!GO:0042623;ATPase activity, coupled;4.70727059754211e-15!GO:0006913;nucleocytoplasmic transport;6.31714713306238e-15!GO:0006457;protein folding;6.71661006456835e-15!GO:0000398;nuclear mRNA splicing, via spliceosome;7.38723797831294e-15!GO:0000375;RNA splicing, via transesterification reactions;7.38723797831294e-15!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;7.38723797831294e-15!GO:0051169;nuclear transport;1.06193527541543e-14!GO:0042981;regulation of apoptosis;1.45146361616079e-14!GO:0043067;regulation of programmed cell death;2.41640049806113e-14!GO:0030554;adenyl nucleotide binding;2.57880879240259e-14!GO:0050136;NADH dehydrogenase (quinone) activity;2.87097776488365e-14!GO:0003954;NADH dehydrogenase activity;2.87097776488365e-14!GO:0008137;NADH dehydrogenase (ubiquinone) activity;2.87097776488365e-14!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;3.17345000538196e-14!GO:0030163;protein catabolic process;4.88023511513886e-14!GO:0044248;cellular catabolic process;1.24633538484542e-13!GO:0005694;chromosome;1.54037335357366e-13!GO:0016607;nuclear speck;1.88105565116121e-13!GO:0003743;translation initiation factor activity;2.73417000270624e-13!GO:0012505;endomembrane system;3.46690886420628e-13!GO:0006413;translational initiation;4.67907717935631e-13!GO:0042775;organelle ATP synthesis coupled electron transport;8.56329473846163e-13!GO:0042773;ATP synthesis coupled electron transport;8.56329473846163e-13!GO:0050794;regulation of cellular process;1.16171104973902e-12!GO:0065004;protein-DNA complex assembly;1.88340633565744e-12!GO:0030964;NADH dehydrogenase complex (quinone);2.18608593415017e-12!GO:0045271;respiratory chain complex I;2.18608593415017e-12!GO:0005747;mitochondrial respiratory chain complex I;2.18608593415017e-12!GO:0004386;helicase activity;3.9411084186192e-12!GO:0042254;ribosome biogenesis and assembly;5.29668782718271e-12!GO:0044427;chromosomal part;5.92344835925837e-12!GO:0005635;nuclear envelope;6.24639570415436e-12!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;6.88955369439403e-12!GO:0005761;mitochondrial ribosome;7.06633971656378e-12!GO:0000313;organellar ribosome;7.06633971656378e-12!GO:0008639;small protein conjugating enzyme activity;1.07151611692874e-11!GO:0031965;nuclear membrane;1.34360364803679e-11!GO:0004842;ubiquitin-protein ligase activity;1.65920908685777e-11!GO:0006333;chromatin assembly or disassembly;2.28752416300657e-11!GO:0022402;cell cycle process;2.73132389077272e-11!GO:0019222;regulation of metabolic process;2.73132389077272e-11!GO:0003712;transcription cofactor activity;3.20382970932305e-11!GO:0048770;pigment granule;4.80753619651329e-11!GO:0042470;melanosome;4.80753619651329e-11!GO:0019787;small conjugating protein ligase activity;4.95657833174301e-11!GO:0008026;ATP-dependent helicase activity;4.995265464544e-11!GO:0051082;unfolded protein binding;5.32548715306818e-11!GO:0006446;regulation of translational initiation;6.25791729332891e-11!GO:0016568;chromatin modification;6.48092623815901e-11!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;7.51760907336571e-11!GO:0009719;response to endogenous stimulus;1.24811625866409e-10!GO:0017038;protein import;1.52043991501528e-10!GO:0044453;nuclear membrane part;1.82395683320396e-10!GO:0048193;Golgi vesicle transport;4.17732414780046e-10!GO:0000785;chromatin;6.18310897531274e-10!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.16704945489047e-09!GO:0051186;cofactor metabolic process;1.20971286201987e-09!GO:0031323;regulation of cellular metabolic process;1.38977057762902e-09!GO:0019829;cation-transporting ATPase activity;1.43122610005604e-09!GO:0051726;regulation of cell cycle;1.85124658681128e-09!GO:0006793;phosphorus metabolic process;1.8534798670867e-09!GO:0006796;phosphate metabolic process;1.8534798670867e-09!GO:0000074;regulation of progression through cell cycle;3.28804337428739e-09!GO:0006403;RNA localization;3.34870097938734e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;3.54678993559079e-09!GO:0050657;nucleic acid transport;3.56966113449167e-09!GO:0051236;establishment of RNA localization;3.56966113449167e-09!GO:0050658;RNA transport;3.56966113449167e-09!GO:0005643;nuclear pore;4.26685969739608e-09!GO:0016881;acid-amino acid ligase activity;6.01211312946801e-09!GO:0006334;nucleosome assembly;6.31663326834961e-09!GO:0007249;I-kappaB kinase/NF-kappaB cascade;6.70833761323833e-09!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;9.9305886041011e-09!GO:0006350;transcription;1.02575733257748e-08!GO:0031497;chromatin assembly;1.1149084216078e-08!GO:0016072;rRNA metabolic process;1.19619640118754e-08!GO:0006364;rRNA processing;1.52769159230556e-08!GO:0030532;small nuclear ribonucleoprotein complex;1.5303171165958e-08!GO:0005794;Golgi apparatus;2.24088581035883e-08!GO:0015078;hydrogen ion transmembrane transporter activity;2.42017866818724e-08!GO:0005768;endosome;2.679169612758e-08!GO:0043566;structure-specific DNA binding;2.74682479986745e-08!GO:0016787;hydrolase activity;2.94741801485268e-08!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;3.05705955669496e-08!GO:0008270;zinc ion binding;3.1149226215237e-08!GO:0006366;transcription from RNA polymerase II promoter;3.13388042620143e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;3.27896960410617e-08!GO:0007243;protein kinase cascade;3.42308012347172e-08!GO:0050789;regulation of biological process;3.76090931687348e-08!GO:0032446;protein modification by small protein conjugation;3.85448487165207e-08!GO:0016310;phosphorylation;3.87976243516546e-08!GO:0009259;ribonucleotide metabolic process;4.02734805818421e-08!GO:0005839;proteasome core complex (sensu Eukaryota);5.91197458229002e-08!GO:0008565;protein transporter activity;7.56123629014913e-08!GO:0003713;transcription coactivator activity;7.64846692430194e-08!GO:0006399;tRNA metabolic process;8.73429628236297e-08!GO:0010468;regulation of gene expression;9.17226406305575e-08!GO:0009260;ribonucleotide biosynthetic process;9.69934902112408e-08!GO:0016567;protein ubiquitination;9.93910137618452e-08!GO:0006916;anti-apoptosis;9.9715681399351e-08!GO:0006164;purine nucleotide biosynthetic process;1.03843624201752e-07!GO:0065002;intracellular protein transport across a membrane;1.0936615363232e-07!GO:0043069;negative regulation of programmed cell death;1.30269531404177e-07!GO:0051028;mRNA transport;1.34803853397734e-07!GO:0051170;nuclear import;1.35782660230594e-07!GO:0006732;coenzyme metabolic process;1.46888041854774e-07!GO:0016564;transcription repressor activity;1.48355173030468e-07!GO:0003697;single-stranded DNA binding;1.7933725475861e-07!GO:0006163;purine nucleotide metabolic process;1.81188855540222e-07!GO:0046930;pore complex;1.87293378145145e-07!GO:0004298;threonine endopeptidase activity;1.90055066772287e-07!GO:0043066;negative regulation of apoptosis;1.92078497932752e-07!GO:0009152;purine ribonucleotide biosynthetic process;2.25464436079101e-07!GO:0009056;catabolic process;2.32365682036483e-07!GO:0048523;negative regulation of cellular process;2.39184462486413e-07!GO:0006917;induction of apoptosis;2.3998451676395e-07!GO:0015986;ATP synthesis coupled proton transport;2.40063663829985e-07!GO:0015985;energy coupled proton transport, down electrochemical gradient;2.40063663829985e-07!GO:0006606;protein import into nucleus;2.42191099459189e-07!GO:0031324;negative regulation of cellular metabolic process;2.42191099459189e-07!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.08703570064329e-07!GO:0012502;induction of programmed cell death;3.86524179118424e-07!GO:0009150;purine ribonucleotide metabolic process;4.08808731387709e-07!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;4.20409119562931e-07!GO:0051246;regulation of protein metabolic process;4.74051412875769e-07!GO:0043065;positive regulation of apoptosis;4.80899852287194e-07!GO:0000151;ubiquitin ligase complex;7.69364493289691e-07!GO:0043068;positive regulation of programmed cell death;7.85247188993615e-07!GO:0009055;electron carrier activity;8.13680698159238e-07!GO:0016740;transferase activity;8.42732640888925e-07!GO:0009060;aerobic respiration;8.59499155825721e-07!GO:0000278;mitotic cell cycle;9.28792759117734e-07!GO:0016563;transcription activator activity;9.68381131990777e-07!GO:0016779;nucleotidyltransferase activity;9.68381131990777e-07!GO:0044432;endoplasmic reticulum part;1.06397770707715e-06!GO:0000245;spliceosome assembly;1.09638563904414e-06!GO:0032774;RNA biosynthetic process;1.15716478936452e-06!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;1.32509880486016e-06!GO:0015399;primary active transmembrane transporter activity;1.32509880486016e-06!GO:0006754;ATP biosynthetic process;1.41538239031281e-06!GO:0006753;nucleoside phosphate metabolic process;1.41538239031281e-06!GO:0006351;transcription, DNA-dependent;1.43634963479432e-06!GO:0009142;nucleoside triphosphate biosynthetic process;1.47705757278267e-06!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.47705757278267e-06!GO:0016192;vesicle-mediated transport;1.52153794077512e-06!GO:0016469;proton-transporting two-sector ATPase complex;1.55950406321117e-06!GO:0005783;endoplasmic reticulum;1.68092031977953e-06!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.76409900864875e-06!GO:0051168;nuclear export;2.04459928637604e-06!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.18842925868197e-06!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.18842925868197e-06!GO:0065009;regulation of a molecular function;2.3221363622651e-06!GO:0006260;DNA replication;2.43129527654602e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;2.51234977117965e-06!GO:0003724;RNA helicase activity;2.53461983345799e-06!GO:0051188;cofactor biosynthetic process;2.54332295020587e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;3.11503696766395e-06!GO:0006888;ER to Golgi vesicle-mediated transport;3.26964524199432e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;3.83951605693682e-06!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;4.09968184072709e-06!GO:0042175;nuclear envelope-endoplasmic reticulum network;4.1664371723848e-06!GO:0048519;negative regulation of biological process;4.23267626627593e-06!GO:0009892;negative regulation of metabolic process;4.4833990432299e-06!GO:0045259;proton-transporting ATP synthase complex;4.4833990432299e-06!GO:0005789;endoplasmic reticulum membrane;4.5310806874345e-06!GO:0009199;ribonucleoside triphosphate metabolic process;4.652596700579e-06!GO:0045786;negative regulation of progression through cell cycle;4.6993103702886e-06!GO:0007005;mitochondrion organization and biogenesis;4.90259327154699e-06!GO:0045333;cellular respiration;4.91546670138783e-06!GO:0019899;enzyme binding;4.95167965335375e-06!GO:0045449;regulation of transcription;5.30844115529321e-06!GO:0009141;nucleoside triphosphate metabolic process;5.30844115529321e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;6.59959086839333e-06!GO:0009205;purine ribonucleoside triphosphate metabolic process;6.70252619173188e-06!GO:0009144;purine nucleoside triphosphate metabolic process;6.70252619173188e-06!GO:0046034;ATP metabolic process;7.50229374314503e-06!GO:0046914;transition metal ion binding;8.01972133463447e-06!GO:0006613;cotranslational protein targeting to membrane;1.35251662261004e-05!GO:0016481;negative regulation of transcription;1.55312449617682e-05!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.64863670244549e-05!GO:0004812;aminoacyl-tRNA ligase activity;1.64863670244549e-05!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.64863670244549e-05!GO:0000786;nucleosome;1.93651112916261e-05!GO:0006401;RNA catabolic process;2.10619336733357e-05!GO:0030120;vesicle coat;2.79352767480659e-05!GO:0030662;coated vesicle membrane;2.79352767480659e-05!GO:0043492;ATPase activity, coupled to movement of substances;2.98892250651078e-05!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;3.13784067773489e-05!GO:0043038;amino acid activation;3.19742982839503e-05!GO:0006418;tRNA aminoacylation for protein translation;3.19742982839503e-05!GO:0043039;tRNA aminoacylation;3.19742982839503e-05!GO:0005813;centrosome;3.26348998028599e-05!GO:0016363;nuclear matrix;3.40251175111881e-05!GO:0065007;biological regulation;3.60924096359313e-05!GO:0003677;DNA binding;3.61830004524583e-05!GO:0048475;coated membrane;3.95226674563206e-05!GO:0030117;membrane coat;3.95226674563206e-05!GO:0005793;ER-Golgi intermediate compartment;4.05268326710581e-05!GO:0009108;coenzyme biosynthetic process;4.09951736910522e-05!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;4.19449038304428e-05!GO:0008186;RNA-dependent ATPase activity;4.41896528778702e-05!GO:0006355;regulation of transcription, DNA-dependent;4.50121771911258e-05!GO:0004674;protein serine/threonine kinase activity;4.59039136971915e-05!GO:0006099;tricarboxylic acid cycle;6.16092098548706e-05!GO:0046356;acetyl-CoA catabolic process;6.16092098548706e-05!GO:0022403;cell cycle phase;6.26989983785702e-05!GO:0006612;protein targeting to membrane;6.27842227661053e-05!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;6.45140381685785e-05!GO:0006402;mRNA catabolic process;6.96802212825743e-05!GO:0005852;eukaryotic translation initiation factor 3 complex;6.97072855671421e-05!GO:0007242;intracellular signaling cascade;7.01304323972318e-05!GO:0006417;regulation of translation;7.2763711217314e-05!GO:0008234;cysteine-type peptidase activity;7.47023503755369e-05!GO:0006310;DNA recombination;7.57944156850621e-05!GO:0006461;protein complex assembly;7.59717213906347e-05!GO:0006752;group transfer coenzyme metabolic process;8.08252290159514e-05!GO:0005770;late endosome;9.14047489277497e-05!GO:0005815;microtubule organizing center;9.59630405507609e-05!GO:0044431;Golgi apparatus part;0.00010095343424623!GO:0005762;mitochondrial large ribosomal subunit;0.000103601919951162!GO:0000315;organellar large ribosomal subunit;0.000103601919951162!GO:0006084;acetyl-CoA metabolic process;0.000104562216623719!GO:0051301;cell division;0.000116107280833106!GO:0005773;vacuole;0.000116107280833106!GO:0005525;GTP binding;0.000126569974455576!GO:0004004;ATP-dependent RNA helicase activity;0.000138437408678888!GO:0060090;molecular adaptor activity;0.000151442179913246!GO:0044440;endosomal part;0.000162640139055058!GO:0010008;endosome membrane;0.000162640139055058!GO:0000087;M phase of mitotic cell cycle;0.000168104451852511!GO:0003714;transcription corepressor activity;0.000172232732361164!GO:0008654;phospholipid biosynthetic process;0.000208623876226226!GO:0007067;mitosis;0.000220316087749468!GO:0005885;Arp2/3 protein complex;0.000225038172510525!GO:0043021;ribonucleoprotein binding;0.000236380953461154!GO:0003690;double-stranded DNA binding;0.000274474044120482!GO:0031326;regulation of cellular biosynthetic process;0.000274932202904156!GO:0030384;phosphoinositide metabolic process;0.000290975432429398!GO:0006261;DNA-dependent DNA replication;0.000296127463988309!GO:0051427;hormone receptor binding;0.000337053224028067!GO:0003729;mRNA binding;0.000338855070476085!GO:0009109;coenzyme catabolic process;0.000355511028531463!GO:0019843;rRNA binding;0.000360989462692875!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000362315395178446!GO:0005769;early endosome;0.000367995240040393!GO:0048522;positive regulation of cellular process;0.000374358711138756!GO:0006352;transcription initiation;0.0003760698693754!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000381431628584803!GO:0008632;apoptotic program;0.00039076535599519!GO:0005667;transcription factor complex;0.000392117284819286!GO:0042110;T cell activation;0.000412860615980901!GO:0006891;intra-Golgi vesicle-mediated transport;0.000419479326198203!GO:0000323;lytic vacuole;0.000419479326198203!GO:0005764;lysosome;0.000419479326198203!GO:0009615;response to virus;0.000419852722303841!GO:0008168;methyltransferase activity;0.000420311212878539!GO:0016251;general RNA polymerase II transcription factor activity;0.000424766511647102!GO:0016741;transferase activity, transferring one-carbon groups;0.000460466406006455!GO:0043623;cellular protein complex assembly;0.000463534912075963!GO:0051187;cofactor catabolic process;0.000479154176950556!GO:0015992;proton transport;0.000484980551291801!GO:0006818;hydrogen transport;0.000515353131597401!GO:0003899;DNA-directed RNA polymerase activity;0.000516074477895881!GO:0003924;GTPase activity;0.000581261070862149!GO:0009117;nucleotide metabolic process;0.000587234247340538!GO:0035257;nuclear hormone receptor binding;0.000637440593214135!GO:0006414;translational elongation;0.000651394692219937!GO:0006611;protein export from nucleus;0.000680839951573686!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000691927575820764!GO:0046489;phosphoinositide biosynthetic process;0.000706575013726121!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000755609300221166!GO:0045892;negative regulation of transcription, DNA-dependent;0.000846088046879905!GO:0006650;glycerophospholipid metabolic process;0.000847319671463883!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00086039296905874!GO:0015630;microtubule cytoskeleton;0.00112155640590788!GO:0000314;organellar small ribosomal subunit;0.0012296118908582!GO:0005763;mitochondrial small ribosomal subunit;0.0012296118908582!GO:0032561;guanyl ribonucleotide binding;0.00136122645591325!GO:0019001;guanyl nucleotide binding;0.00136122645591325!GO:0006383;transcription from RNA polymerase III promoter;0.00137353305913346!GO:0051252;regulation of RNA metabolic process;0.00138672468827422!GO:0015631;tubulin binding;0.00144199601587358!GO:0009889;regulation of biosynthetic process;0.00161465870514057!GO:0008033;tRNA processing;0.00161947913823924!GO:0000139;Golgi membrane;0.00163764325497745!GO:0043681;protein import into mitochondrion;0.00170158388871177!GO:0000279;M phase;0.00172175412573015!GO:0005798;Golgi-associated vesicle;0.001734035957192!GO:0031072;heat shock protein binding;0.00174241575127436!GO:0051090;regulation of transcription factor activity;0.00174270418326315!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00174270418326315!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00174270418326315!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00174270418326315!GO:0022890;inorganic cation transmembrane transporter activity;0.00175030330649306!GO:0046474;glycerophospholipid biosynthetic process;0.0017708805302992!GO:0051087;chaperone binding;0.0017905810193466!GO:0048471;perinuclear region of cytoplasm;0.0018103311836767!GO:0051251;positive regulation of lymphocyte activation;0.00186720400433907!GO:0006302;double-strand break repair;0.00199701566644969!GO:0050790;regulation of catalytic activity;0.00208918362737372!GO:0051789;response to protein stimulus;0.00246035748546072!GO:0006986;response to unfolded protein;0.00246035748546072!GO:0003678;DNA helicase activity;0.00257858454892445!GO:0005741;mitochondrial outer membrane;0.00259848106498649!GO:0004518;nuclease activity;0.00272408987999023!GO:0005684;U2-dependent spliceosome;0.00274765130974426!GO:0019783;small conjugating protein-specific protease activity;0.00278797595061563!GO:0005637;nuclear inner membrane;0.00279263410719807!GO:0005070;SH3/SH2 adaptor activity;0.00292201412981348!GO:0006607;NLS-bearing substrate import into nucleus;0.00295153836267092!GO:0048500;signal recognition particle;0.00297924147987818!GO:0003746;translation elongation factor activity;0.00299215858044224!GO:0006289;nucleotide-excision repair;0.00309771337875502!GO:0019867;outer membrane;0.00312875738712689!GO:0004527;exonuclease activity;0.00312875738712689!GO:0016197;endosome transport;0.0031297591347302!GO:0004843;ubiquitin-specific protease activity;0.00337577805611562!GO:0008047;enzyme activator activity;0.00337577805611562!GO:0008022;protein C-terminus binding;0.00351887530413672!GO:0005657;replication fork;0.0036104045549011!GO:0006405;RNA export from nucleus;0.00389905705661874!GO:0048487;beta-tubulin binding;0.00408509070328725!GO:0044452;nucleolar part;0.00411896511655188!GO:0008312;7S RNA binding;0.00418601985338613!GO:0031968;organelle outer membrane;0.00440006705702996!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00475809590877248!GO:0045047;protein targeting to ER;0.00475809590877248!GO:0000287;magnesium ion binding;0.00490749366474846!GO:0046822;regulation of nucleocytoplasmic transport;0.00505911052504831!GO:0051052;regulation of DNA metabolic process;0.00512199674599665!GO:0009967;positive regulation of signal transduction;0.00521601438492047!GO:0046649;lymphocyte activation;0.00536267242254115!GO:0051539;4 iron, 4 sulfur cluster binding;0.00537324382314356!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.00545423497266496!GO:0016272;prefoldin complex;0.00552141919153736!GO:0003711;transcription elongation regulator activity;0.00563306168160852!GO:0006338;chromatin remodeling;0.00573604053594288!GO:0004221;ubiquitin thiolesterase activity;0.00575395134574777!GO:0016790;thiolester hydrolase activity;0.00578272718495809!GO:0042802;identical protein binding;0.00580315309619791!GO:0003684;damaged DNA binding;0.00585467202359806!GO:0007006;mitochondrial membrane organization and biogenesis;0.00597481190964748!GO:0043488;regulation of mRNA stability;0.00604083403181536!GO:0043487;regulation of RNA stability;0.00604083403181536!GO:0050863;regulation of T cell activation;0.00615256070273722!GO:0051249;regulation of lymphocyte activation;0.0062651273848583!GO:0050865;regulation of cell activation;0.00631648224401935!GO:0007050;cell cycle arrest;0.00631777321978587!GO:0005774;vacuolar membrane;0.0063295648196426!GO:0046966;thyroid hormone receptor binding;0.00644929898487603!GO:0050811;GABA receptor binding;0.00647268260221442!GO:0030658;transport vesicle membrane;0.00648622449724051!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00648622449724051!GO:0015002;heme-copper terminal oxidase activity;0.00648622449724051!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00648622449724051!GO:0004129;cytochrome-c oxidase activity;0.00648622449724051!GO:0046467;membrane lipid biosynthetic process;0.0066633179904027!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0068143213313026!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0068143213313026!GO:0016584;nucleosome positioning;0.00701694939635744!GO:0032259;methylation;0.0071819073836534!GO:0005669;transcription factor TFIID complex;0.00733678560751907!GO:0000209;protein polyubiquitination;0.00759901058018374!GO:0048518;positive regulation of biological process;0.00762801589978699!GO:0043414;biopolymer methylation;0.00774878824928614!GO:0051059;NF-kappaB binding;0.00780518593919307!GO:0007264;small GTPase mediated signal transduction;0.00810396743054683!GO:0031625;ubiquitin protein ligase binding;0.00812431563942834!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0081821738267682!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00827206059056685!GO:0001667;ameboidal cell migration;0.00838030799076528!GO:0032027;myosin light chain binding;0.00838030799076528!GO:0050870;positive regulation of T cell activation;0.00846604869443293!GO:0004532;exoribonuclease activity;0.00867614176915383!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00867614176915383!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0087060207699937!GO:0008624;induction of apoptosis by extracellular signals;0.00879001937467627!GO:0031902;late endosome membrane;0.00887704619429036!GO:0043621;protein self-association;0.00919266229259074!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00923597512078869!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00923779640805609!GO:0022415;viral reproductive process;0.00961320289409033!GO:0006839;mitochondrial transport;0.00961436323701956!GO:0030518;steroid hormone receptor signaling pathway;0.00961436323701956!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00962817581497561!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.0096510327263379!GO:0043433;negative regulation of transcription factor activity;0.00966564774836826!GO:0006626;protein targeting to mitochondrion;0.010140870124829!GO:0006914;autophagy;0.0103906286889889!GO:0005869;dynactin complex;0.0104695837340751!GO:0006497;protein amino acid lipidation;0.0105776366103078!GO:0030118;clathrin coat;0.0107964725243187!GO:0016859;cis-trans isomerase activity;0.0107964725243187!GO:0051092;activation of NF-kappaB transcription factor;0.0108126471479144!GO:0051329;interphase of mitotic cell cycle;0.0114693425136941!GO:0050852;T cell receptor signaling pathway;0.0115135540393628!GO:0019901;protein kinase binding;0.0117052398260475!GO:0006506;GPI anchor biosynthetic process;0.0117155246377939!GO:0008408;3'-5' exonuclease activity;0.0118850973942593!GO:0005765;lysosomal membrane;0.0118850973942593!GO:0006376;mRNA splice site selection;0.0121682930796186!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0121682930796186!GO:0007265;Ras protein signal transduction;0.0125626437527473!GO:0000049;tRNA binding;0.0126313553140335!GO:0044437;vacuolar part;0.0127202319498133!GO:0030521;androgen receptor signaling pathway;0.0128857962175967!GO:0016853;isomerase activity;0.0132303206192269!GO:0048468;cell development;0.0133013073898862!GO:0051920;peroxiredoxin activity;0.0133340574697051!GO:0051540;metal cluster binding;0.0135284458328482!GO:0051536;iron-sulfur cluster binding;0.0135284458328482!GO:0033116;ER-Golgi intermediate compartment membrane;0.0137755047834778!GO:0008017;microtubule binding;0.0140605847211713!GO:0006505;GPI anchor metabolic process;0.0141613645428128!GO:0030660;Golgi-associated vesicle membrane;0.0142730755431638!GO:0008094;DNA-dependent ATPase activity;0.0143748158023914!GO:0031124;mRNA 3'-end processing;0.0147026379760373!GO:0051325;interphase;0.0147362730179786!GO:0005048;signal sequence binding;0.0147906465767761!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0152797359040865!GO:0008139;nuclear localization sequence binding;0.0154101783749272!GO:0004576;oligosaccharyl transferase activity;0.0154910935037537!GO:0009165;nucleotide biosynthetic process;0.0155465478942095!GO:0051223;regulation of protein transport;0.0155465478942095!GO:0047485;protein N-terminus binding;0.0158614291993184!GO:0007034;vacuolar transport;0.0159031523863192!GO:0015980;energy derivation by oxidation of organic compounds;0.0159328410030701!GO:0000776;kinetochore;0.0161356820765636!GO:0051098;regulation of binding;0.0169261651581648!GO:0000738;DNA catabolic process, exonucleolytic;0.0169261651581648!GO:0016311;dephosphorylation;0.0170532764246837!GO:0043022;ribosome binding;0.0172153794569968!GO:0042101;T cell receptor complex;0.0175629291552734!GO:0003725;double-stranded RNA binding;0.0177211791284556!GO:0009116;nucleoside metabolic process;0.0178165973919024!GO:0008276;protein methyltransferase activity;0.0178350368529707!GO:0008250;oligosaccharyl transferase complex;0.0178813815433703!GO:0000082;G1/S transition of mitotic cell cycle;0.0184379499314129!GO:0045454;cell redox homeostasis;0.0184379499314129!GO:0016788;hydrolase activity, acting on ester bonds;0.0191660520608312!GO:0045603;positive regulation of endothelial cell differentiation;0.0193281528149932!GO:0032981;mitochondrial respiratory chain complex I assembly;0.019488656282223!GO:0010257;NADH dehydrogenase complex assembly;0.019488656282223!GO:0033108;mitochondrial respiratory chain complex assembly;0.019488656282223!GO:0051235;maintenance of localization;0.0198189600264273!GO:0008637;apoptotic mitochondrial changes;0.0198447076814584!GO:0006284;base-excision repair;0.0200535985567311!GO:0019955;cytokine binding;0.0203540691415089!GO:0006672;ceramide metabolic process;0.0210976171244666!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0215891672008673!GO:0030833;regulation of actin filament polymerization;0.0217322173111568!GO:0019900;kinase binding;0.0224725569733729!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.0229803669566631!GO:0030522;intracellular receptor-mediated signaling pathway;0.0232630751476961!GO:0000178;exosome (RNase complex);0.0232989445642648!GO:0016791;phosphoric monoester hydrolase activity;0.0235931925150587!GO:0005819;spindle;0.0236299207365406!GO:0006595;polyamine metabolic process;0.0241179492341701!GO:0003682;chromatin binding;0.0241179492341701!GO:0051336;regulation of hydrolase activity;0.0241390323912739!GO:0005521;lamin binding;0.0241390323912739!GO:0008287;protein serine/threonine phosphatase complex;0.0241390323912739!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0257085072471307!GO:0031123;RNA 3'-end processing;0.0258539125123088!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.0262217958049193!GO:0031252;leading edge;0.0263868912705869!GO:0040029;regulation of gene expression, epigenetic;0.0266509966310292!GO:0006091;generation of precursor metabolites and energy;0.0270588170044981!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0273320303648154!GO:0031647;regulation of protein stability;0.0281108481007072!GO:0042158;lipoprotein biosynthetic process;0.0281108498976953!GO:0000075;cell cycle checkpoint;0.0281969328913595!GO:0016301;kinase activity;0.0281970608078871!GO:0015923;mannosidase activity;0.0285750766520603!GO:0031982;vesicle;0.0287281065834304!GO:0030880;RNA polymerase complex;0.0288303399205403!GO:0019210;kinase inhibitor activity;0.02909787683848!GO:0005095;GTPase inhibitor activity;0.0292122190334463!GO:0030137;COPI-coated vesicle;0.0292226060699155!GO:0008097;5S rRNA binding;0.0299844836677744!GO:0033549;MAP kinase phosphatase activity;0.0308276138440452!GO:0017017;MAP kinase tyrosine/serine/threonine phosphatase activity;0.0308276138440452!GO:0008320;protein transmembrane transporter activity;0.0310252099900243!GO:0032508;DNA duplex unwinding;0.0314521359021667!GO:0032392;DNA geometric change;0.0314521359021667!GO:0030125;clathrin vesicle coat;0.0314521359021667!GO:0030665;clathrin coated vesicle membrane;0.0314521359021667!GO:0000090;mitotic anaphase;0.0325203320867831!GO:0051322;anaphase;0.0325203320867831!GO:0016605;PML body;0.0331302012917859!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0334211092241878!GO:0007021;tubulin folding;0.033514645485275!GO:0044438;microbody part;0.033789934925025!GO:0044439;peroxisomal part;0.033789934925025!GO:0030695;GTPase regulator activity;0.0338539095405368!GO:0004197;cysteine-type endopeptidase activity;0.0338937059627013!GO:0004003;ATP-dependent DNA helicase activity;0.0340616785367447!GO:0005832;chaperonin-containing T-complex;0.0346940114791961!GO:0004722;protein serine/threonine phosphatase activity;0.0349012187352469!GO:0008180;signalosome;0.0361116535121998!GO:0042608;T cell receptor binding;0.0361849184203866!GO:0019976;interleukin-2 binding;0.0367383097567915!GO:0004911;interleukin-2 receptor activity;0.0367383097567915!GO:0032200;telomere organization and biogenesis;0.0369543867207131!GO:0000723;telomere maintenance;0.0369543867207131!GO:0006144;purine base metabolic process;0.0370428368934896!GO:0000119;mediator complex;0.0375250517949122!GO:0000303;response to superoxide;0.0377512441159342!GO:0004721;phosphoprotein phosphatase activity;0.0377512441159342!GO:0017091;AU-rich element binding;0.0380476105672191!GO:0050779;RNA destabilization;0.0380476105672191!GO:0000289;poly(A) tail shortening;0.0380476105672191!GO:0030663;COPI coated vesicle membrane;0.0380984192508!GO:0030126;COPI vesicle coat;0.0380984192508!GO:0019904;protein domain specific binding;0.0380984192508!GO:0004659;prenyltransferase activity;0.0381343945099893!GO:0002820;negative regulation of adaptive immune response;0.0384531659617027!GO:0002823;negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0384531659617027!GO:0043281;regulation of caspase activity;0.0387099468981162!GO:0001772;immunological synapse;0.0388303713221474!GO:0004860;protein kinase inhibitor activity;0.0389339081528608!GO:0046426;negative regulation of JAK-STAT cascade;0.0390008182081954!GO:0031988;membrane-bound vesicle;0.0390457714237156!GO:0000175;3'-5'-exoribonuclease activity;0.0390797874631197!GO:0000096;sulfur amino acid metabolic process;0.0391890551719996!GO:0006354;RNA elongation;0.039290905185331!GO:0022411;cellular component disassembly;0.039290905185331!GO:0000288;mRNA catabolic process, deadenylation-dependent decay;0.0394404668245314!GO:0008538;proteasome activator activity;0.040115482685651!GO:0045321;leukocyte activation;0.0401266100561078!GO:0022884;macromolecule transmembrane transporter activity;0.0401698696963377!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0401698696963377!GO:0046519;sphingoid metabolic process;0.0405141984320138!GO:0006007;glucose catabolic process;0.0410803525733664!GO:0022406;membrane docking;0.0412912463082688!GO:0048278;vesicle docking;0.0412912463082688!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0416842997987901!GO:0032940;secretion by cell;0.0423002185892145!GO:0018196;peptidyl-asparagine modification;0.0423002185892145!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0423002185892145!GO:0051287;NAD binding;0.0423079778021491!GO:0007004;telomere maintenance via telomerase;0.042811107378171!GO:0008138;protein tyrosine/serine/threonine phosphatase activity;0.0429723531739051!GO:0006904;vesicle docking during exocytosis;0.0431785477931978!GO:0033367;protein localization in mast cell secretory granule;0.0431785477931978!GO:0033365;protein localization in organelle;0.0431785477931978!GO:0033371;T cell secretory granule organization and biogenesis;0.0431785477931978!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.0431785477931978!GO:0033375;protease localization in T cell secretory granule;0.0431785477931978!GO:0042629;mast cell granule;0.0431785477931978!GO:0033377;maintenance of protein localization in T cell secretory granule;0.0431785477931978!GO:0033364;mast cell secretory granule organization and biogenesis;0.0431785477931978!GO:0033380;granzyme B localization in T cell secretory granule;0.0431785477931978!GO:0033379;maintenance of protease localization in T cell secretory granule;0.0431785477931978!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.0431785477931978!GO:0033368;protease localization in mast cell secretory granule;0.0431785477931978!GO:0033366;protein localization in secretory granule;0.0431785477931978!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.0431785477931978!GO:0033374;protein localization in T cell secretory granule;0.0431785477931978!GO:0030867;rough endoplasmic reticulum membrane;0.0431785477931978!GO:0006470;protein amino acid dephosphorylation;0.0433072900579134!GO:0016585;chromatin remodeling complex;0.043793364322192!GO:0009112;nucleobase metabolic process;0.0441254791445456!GO:0046979;TAP2 binding;0.0443180613020467!GO:0046977;TAP binding;0.0443180613020467!GO:0046978;TAP1 binding;0.0443180613020467!GO:0030258;lipid modification;0.0452389579905712!GO:0031901;early endosome membrane;0.0454125427349839!GO:0000152;nuclear ubiquitin ligase complex;0.0455863898573717!GO:0004177;aminopeptidase activity;0.0458441750841615!GO:0030127;COPII vesicle coat;0.0460059987751436!GO:0012507;ER to Golgi transport vesicle membrane;0.0460059987751436!GO:0006919;caspase activation;0.046248036151425!GO:0031903;microbody membrane;0.0472093257121118!GO:0005778;peroxisomal membrane;0.0472093257121118!GO:0030041;actin filament polymerization;0.0476693572785446!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.0477374984003263!GO:0000428;DNA-directed RNA polymerase complex;0.0477374984003263!GO:0042393;histone binding;0.0484729937358576!GO:0035258;steroid hormone receptor binding;0.0493434251123289!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0494346750933566!GO:0046588;negative regulation of calcium-dependent cell-cell adhesion;0.0495612148464385!GO:0046586;regulation of calcium-dependent cell-cell adhesion;0.0495612148464385!GO:0005096;GTPase activator activity;0.049668850261121 | |||
|sample_id=11782 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=PAX3,7:3.4766607184;FOX{F1,F2,J1}:2.83312758391;RUNX1..3:2.61305154757;CREB1:2.55399074845;FOX{D1,D2}:2.54837058105;ATF5_CREB3:2.53867265692;TLX2:2.41683647031;ELF1,2,4:2.41084125305;BPTF:2.29972049305;CDX1,2,4:2.25309914224;ATF4:2.22124040993;DMAP1_NCOR{1,2}_SMARC:2.15744557659;RORA:1.93810804791;PDX1:1.85899916877;HMX1:1.81104852476;FOXO1,3,4:1.79074888729;ETS1,2:1.72978690634;ZBTB16:1.72528973738;PAX4:1.72302139531;FOX{I1,J2}:1.57105747101;PAX2:1.3606690767;SPI1:1.3058164635;FOXN1:1.2682476841;JUN:1.26415772106;RFX2..5_RFXANK_RFXAP:1.13885318223;ELK1,4_GABP{A,B1}:1.07452195083;FOXP1:1.05442202169;PBX1:1.04953425923;IRF1,2:1.0096873943;HIF1A:0.982716444212;ATF6:0.981218145905;SPIB:0.899990366683;ATF2:0.876486688912;TGIF1:0.841838319346;GATA6:0.829192345314;IKZF2:0.791669807097;NKX3-1:0.751839279005;POU1F1:0.747786974266;NANOG{mouse}:0.744122814607;T:0.730374157595;NKX2-2,8:0.626121969112;NKX6-1,2:0.62423928482;NFIL3:0.620101856787;PAX6:0.618978331769;BREu{core}:0.607075080682;MYOD1:0.589639628429;CUX2:0.561916567327;SOX2:0.546110425644;PITX1..3:0.543810688369;ZEB1:0.536084358141;STAT1,3:0.513426608743;LEF1_TCF7_TCF7L1,2:0.49952646964;NKX2-1,4:0.488090962347;SNAI1..3:0.466599646363;ALX1:0.45310599679;YY1:0.427690056289;NFKB1_REL_RELA:0.4254039672;FOXQ1:0.391945494028;IRF7:0.353335052376;NFATC1..3:0.333815967437;RFX1:0.296636860759;MAFB:0.265005890858;POU2F1..3:0.216949632188;SPZ1:0.181407421422;SREBF1,2:0.146327076982;EP300:0.140582578959;HES1:0.109576310725;HAND1,2:0.0908933579866;AIRE:0.0827329394155;MYB:0.069845221483;AHR_ARNT_ARNT2:0.0597133726338;LMO2:0.0467484255918;HOX{A6,A7,B6,B7}:0.0448031233903;NFIX:0.0435720571543;CRX:-0.0103745762603;SOX5:-0.0962277898652;EVI1:-0.102927360605;NR5A1,2:-0.11515019797;OCT4_SOX2{dimer}:-0.122793950387;E2F1..5:-0.135939130637;TAL1_TCF{3,4,12}:-0.162136209081;STAT2,4,6:-0.17903635788;NFE2L1:-0.188896667803;NANOG:-0.192619887305;NFY{A,B,C}:-0.202255289425;ZNF384:-0.21675812219;NRF1:-0.228394104133;STAT5{A,B}:-0.274287084741;FOXA2:-0.277171433575;HOXA9_MEIS1:-0.296379409572;DBP:-0.300048954945;TBX4,5:-0.339862226124;GFI1:-0.347167566971;CEBPA,B_DDIT3:-0.358523096925;FOS_FOS{B,L1}_JUN{B,D}:-0.374890083937;HBP1_HMGB_SSRP1_UBTF:-0.379133527451;VSX1,2:-0.382588263971;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.384080621511;HLF:-0.391843490759;NHLH1,2:-0.403036044478;FOSL2:-0.409616273902;AR:-0.440034727424;HNF4A_NR2F1,2:-0.459738683815;TOPORS:-0.464725125556;BACH2:-0.473300812221;NFE2:-0.511051805924;PRRX1,2:-0.512435970738;HNF1A:-0.537168047504;FOXM1:-0.549560923581;ZNF143:-0.603488346553;HMGA1,2:-0.604568689456;MYFfamily:-0.605886705069;ONECUT1,2:-0.610838344875;ALX4:-0.612260601383;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.616150889801;FOXP3:-0.645734922461;SRF:-0.652805953168;GFI1B:-0.656846574952;SMAD1..7,9:-0.665966504129;POU3F1..4:-0.671851760017;bHLH_family:-0.759764350565;ARID5B:-0.764697973541;ZNF423:-0.79311856669;SOX{8,9,10}:-0.803980425512;PAX8:-0.811675803136;ZNF148:-0.817424551422;EGR1..3:-0.833191477348;ADNP_IRX_SIX_ZHX:-0.85561993714;MED-1{core}:-0.857527141396;GLI1..3:-0.866237849048;NFE2L2:-0.867291601358;HOX{A5,B5}:-0.892223531081;MEF2{A,B,C,D}:-0.928725965694;FOXD3:-0.943523320232;MTF1:-0.952524030075;NR6A1:-0.98109113547;RBPJ:-1.01890748731;FOXL1:-1.02097580479;MYBL2:-1.05260781923;LHX3,4:-1.06353942058;PAX5:-1.0757613098;REST:-1.07680291102;NKX2-3_NKX2-5:-1.07758843614;RREB1:-1.08462790703;GCM1,2:-1.08494006202;UFEwm:-1.09520582442;CDC5L:-1.10978097088;ZFP161:-1.11748849389;TFDP1:-1.15708587949;ESRRA:-1.18683288925;PPARG:-1.21905435471;SOX17:-1.24467650874;ZBTB6:-1.28198540282;TFCP2:-1.31154274981;POU6F1:-1.32112674543;ZNF238:-1.32548706464;TBP:-1.33709084897;MZF1:-1.36202616758;TP53:-1.36309264895;RXRA_VDR{dimer}:-1.36422444023;NR1H4:-1.37364659082;MTE{core}:-1.38263974712;GATA4:-1.38335050762;TFAP4:-1.41157364265;TEF:-1.41540403597;POU5F1:-1.41592364616;PATZ1:-1.46326102822;PRDM1:-1.47098402914;HOX{A4,D4}:-1.48862882139;ZIC1..3:-1.48894447331;TFAP2{A,C}:-1.532819822;MAZ:-1.57510789743;XCPE1{core}:-1.58101125452;TEAD1:-1.60217794259;GTF2I:-1.65069774242;NR3C1:-1.65658307069;HIC1:-1.67347441925;ESR1:-1.70758892982;TFAP2B:-1.72074626613;SP1:-1.7368497134;TLX1..3_NFIC{dimer}:-1.74249591328;XBP1:-1.74916318064;HSF1,2:-1.79140077315;EN1,2:-1.82007266684;GTF2A1,2:-1.97536682258;KLF4:-2.09451443182;RXR{A,B,G}:-2.14810505466;GZF1:-2.15148576487;NKX3-2:-2.22292656785;EBF1:-2.27012512425;PAX1,9:-2.36430398117;IKZF1:-2.79333258511 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11782-124A9;search_select_hide=table117:FF:11782-124A9 | |||
}} | }} |
Latest revision as of 18:19, 4 June 2020
Name: | CD4+CD25+CD45RA- memory regulatory T cells, donor1 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13195 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13195
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13195
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.305 |
10 | 10 | 0.00816 |
100 | 100 | 0.502 |
101 | 101 | 0.215 |
102 | 102 | 0.732 |
103 | 103 | 0.689 |
104 | 104 | 0.924 |
105 | 105 | 0.252 |
106 | 106 | 0.38 |
107 | 107 | 0.0201 |
108 | 108 | 0.923 |
109 | 109 | 0.114 |
11 | 11 | 0.174 |
110 | 110 | 0.811 |
111 | 111 | 0.531 |
112 | 112 | 0.598 |
113 | 113 | 0.345 |
114 | 114 | 0.288 |
115 | 115 | 0.39 |
116 | 116 | 0.402 |
117 | 117 | 0.00386 |
118 | 118 | 0.315 |
119 | 119 | 0.853 |
12 | 12 | 0.754 |
120 | 120 | 0.922 |
121 | 121 | 0.655 |
122 | 122 | 0.57 |
123 | 123 | 2.3267e-4 |
124 | 124 | 0.319 |
125 | 125 | 0.676 |
126 | 126 | 0.527 |
127 | 127 | 0.821 |
128 | 128 | 0.966 |
129 | 129 | 0.909 |
13 | 13 | 0.367 |
130 | 130 | 0.23 |
131 | 131 | 0.973 |
132 | 132 | 0.287 |
133 | 133 | 0.984 |
134 | 134 | 0.925 |
135 | 135 | 0.981 |
136 | 136 | 0.884 |
137 | 137 | 0.0498 |
138 | 138 | 0.33 |
139 | 139 | 0.0833 |
14 | 14 | 0.503 |
140 | 140 | 0.0501 |
141 | 141 | 0.504 |
142 | 142 | 0.236 |
143 | 143 | 0.00179 |
144 | 144 | 0.995 |
145 | 145 | 0.683 |
146 | 146 | 0.8 |
147 | 147 | 0.0412 |
148 | 148 | 0.0971 |
149 | 149 | 0.558 |
15 | 15 | 0.11 |
150 | 150 | 0.753 |
151 | 151 | 0.528 |
152 | 152 | 0.543 |
153 | 153 | 0.631 |
154 | 154 | 0.464 |
155 | 155 | 0.0175 |
156 | 156 | 0.552 |
157 | 157 | 0.181 |
158 | 158 | 0.0275 |
159 | 159 | 0.242 |
16 | 16 | 0.723 |
160 | 160 | 0.523 |
161 | 161 | 0.805 |
162 | 162 | 0.0688 |
163 | 163 | 0.553 |
164 | 164 | 0.0462 |
165 | 165 | 0.573 |
166 | 166 | 0.355 |
167 | 167 | 0.101 |
168 | 168 | 0.914 |
169 | 169 | 0.751 |
17 | 17 | 0.893 |
18 | 18 | 0.846 |
19 | 19 | 0.231 |
2 | 2 | 0.465 |
20 | 20 | 0.372 |
21 | 21 | 0.676 |
22 | 22 | 0.536 |
23 | 23 | 0.605 |
24 | 24 | 0.674 |
25 | 25 | 0.0775 |
26 | 26 | 0.299 |
27 | 27 | 0.649 |
28 | 28 | 0.578 |
29 | 29 | 0.00613 |
3 | 3 | 0.177 |
30 | 30 | 0.0906 |
31 | 31 | 0.869 |
32 | 32 | 0.146 |
33 | 33 | 0.168 |
34 | 34 | 0.344 |
35 | 35 | 0.217 |
36 | 36 | 0.0212 |
37 | 37 | 0.171 |
38 | 38 | 0.97 |
39 | 39 | 0.329 |
4 | 4 | 0.843 |
40 | 40 | 0.425 |
41 | 41 | 0.148 |
42 | 42 | 0.115 |
43 | 43 | 0.378 |
44 | 44 | 0.719 |
45 | 45 | 0.283 |
46 | 46 | 0.312 |
47 | 47 | 0.133 |
48 | 48 | 0.26 |
49 | 49 | 0.123 |
5 | 5 | 0.386 |
50 | 50 | 0.415 |
51 | 51 | 0.724 |
52 | 52 | 0.474 |
53 | 53 | 0.469 |
54 | 54 | 0.931 |
55 | 55 | 0.936 |
56 | 56 | 0.911 |
57 | 57 | 0.481 |
58 | 58 | 0.104 |
59 | 59 | 0.894 |
6 | 6 | 0.993 |
60 | 60 | 0.441 |
61 | 61 | 0.122 |
62 | 62 | 0.122 |
63 | 63 | 0.895 |
64 | 64 | 0.442 |
65 | 65 | 0.885 |
66 | 66 | 0.702 |
67 | 67 | 0.997 |
68 | 68 | 0.888 |
69 | 69 | 0.862 |
7 | 7 | 0.293 |
70 | 70 | 0.0598 |
71 | 71 | 0.0272 |
72 | 72 | 0.0522 |
73 | 73 | 0.48 |
74 | 74 | 0.891 |
75 | 75 | 0.0144 |
76 | 76 | 0.0912 |
77 | 77 | 0.0426 |
78 | 78 | 0.12 |
79 | 79 | 0.576 |
8 | 8 | 0.866 |
80 | 80 | 0.0579 |
81 | 81 | 0.342 |
82 | 82 | 0.0892 |
83 | 83 | 0.826 |
84 | 84 | 0.383 |
85 | 85 | 0.986 |
86 | 86 | 0.154 |
87 | 87 | 0.876 |
88 | 88 | 0.918 |
89 | 89 | 0.121 |
9 | 9 | 0.815 |
90 | 90 | 0.0163 |
91 | 91 | 0.633 |
92 | 92 | 0.365 |
93 | 93 | 0.995 |
94 | 94 | 0.176 |
95 | 95 | 0.0296 |
96 | 96 | 0.277 |
97 | 97 | 0.306 |
98 | 98 | 0.11 |
99 | 99 | 2.53403e-4 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13195
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
CL:0002677 naive regulatory T cell
EFO:0002091 biological replicate
FF:0000002 in vivo cell sample
FF:0000210 human sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0002371 (somatic cell)
0000542 (lymphocyte)
0000219 (motile cell)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0002242 (nucleate cell)
0000255 (eukaryotic cell)
0000791 (mature alpha-beta T cell)
0000084 (T cell)
0000789 (alpha-beta T cell)
0002419 (mature T cell)
0000624 (CD4-positive, alpha-beta T cell)
0000815 (regulatory T cell)
0000898 (naive T cell)
0000792 (CD4-positive, CD25-positive, alpha-beta regulatory T cell)
0002677 (naive regulatory T cell)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000051 (common lymphoid progenitor)
CL:0000790 (immature alpha-beta T cell)