FF:11894-125E4: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005170 | ||
| | |accession_numbers=CAGE;DRX007788;DRR008660;DRZ000085;DRZ001470;DRZ011435;DRZ012820 | ||
| | |ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0001737,UBERON:0000064,UBERON:0004119,UBERON:0000062,UBERON:0000061,UBERON:0000465,UBERON:0000063,UBERON:0000477,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0000072,UBERON:0010317,UBERON:0000065,UBERON:0001004,UBERON:0001557 | ||
| | |ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0000066,CL:0000255 | ||
| | |ancestors_in_disease_facet=DOID:4,DOID:162,DOID:14566,DOID:0050687,DOID:305 | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0000625,FF:0000350,FF:0000632,FF:0104978,FF:0000639,FF:0100297,FF:0101120,FF:0011134 | ||
| | |comment= | ||
| | |created_by= | ||
| | |creation_date= | ||
| | |data_phase=2 | ||
| | |datafreeze_phase=2 | ||
| | |def= | ||
| | |expression_enrichment_score=chr1:201979743..201979762,+!p1@ELF3!1.51!31.42!ELF3;;chr2:238592039..238592054,+!p4@LRRFIP1!1.48!29.12!LRRFIP1;;chr6:10415484..10415508,-!p3@TFAP2A!1.44!26.70!TFAP2A;;chr6:10412600..10412637,-!p1@TFAP2A!1.37!37.08!TFAP2A;;chr5:134369905..134369972,-!p1@PITX1!1.35!32.76!PITX1;;chr1:201979703..201979721,+!p2@ELF3!1.34!20.90!ELF3;;chr6:10415276..10415341,-!p2@TFAP2A!1.33!24.94!TFAP2A;;chr6:126240380..126240430,+!p2@NCOA7!1.31!49.89!NCOA7;;chr6:126240442..126240459,+!p4@NCOA7!1.31!24.40!NCOA7;;chr5:134369879..134369898,-!p2@PITX1!1.31!19.55!PITX1;;chr5:170736243..170736279,+!p1@TLX3!1.18!14.16!TLX3;;chr12:52445218..52445237,+!p1@NR4A1!1.17!174.07!NR4A1;;chr6:1312325..1312340,+!p1@FOXQ1!1.17!22.25!FOXQ1;;chr7:101917447..101917479,+!p4@CUX1!1.07!10.79!CUX1;;chr1:44513995..44514031,+!p1@KLF17!1.07!10.65!KLF17;;chr20:6748325..6748352,+!p1@BMP2!1.06!15.24!BMP2;;chr6:126240356..126240379,+!p7@NCOA7!1.05!12.67!NCOA7;;chr6:126240463..126240489,+!p6@NCOA7!1.05!11.46!NCOA7;;chr12:54380036..54380091,+!p4@HOXC10!1.01!9.17!HOXC10;;chrX:131624056..131624069,-!p2@MBNL3!1.00!12.40!MBNL3;;chr18:55102598..55102623,+!p1@ONECUT2!1.00!9.03!ONECUT2;;chr22:19748231..19748317,+!p1@TBX1!0.99!8.76!TBX1;;chr12:54380404..54380433,+!p3@HOXC10!0.96!8.22!HOXC10;;chr17:46687959..46688007,-!p2@HOXB7!0.95!11.19!HOXB7;;chr12:54378923..54378966,+!p1@HOXC10!0.95!7.96!HOXC10;;chr17:46682321..46682362,-!p1@HOXB6!0.93!7.55!HOXB6;;chr3:69915385..69915438,+!p3@MITF!0.93!7.42!MITF;;chr18:55102628..55102646,+!p2@ONECUT2!0.92!7.28!ONECUT2;;chr6:10412576..10412599,-!p5@TFAP2A!0.90!6.88!TFAP2A;;chr7:101917482..101917507,+!p6@CUX1!0.89!6.74!CUX1;;chr9:100615499..100615519,+!p1@FOXE1!0.89!6.74!FOXE1;;chr6:1389789..1389821,+!p1@FOXF2!0.88!9.17!FOXF2;;chr5:321810..321877,+!p1@AHRR!0.87!21.44!AHRR;;chr7:101917407..101917443,+!p3@CUX1!0.86!6.20!CUX1;;chr17:7492684..7492778,-!p2@SOX15!0.84!13.21!SOX15;;chr17:17726907..17726958,-!p2@SREBF1!0.83!37.75!SREBF1;;chrX:131623044..131623089,-!p1@MBNL3!0.82!24.67!MBNL3;;chr10:51572408..51572454,+!p3@NCOA4!0.81!34.38!NCOA4;;chr9:102584262..102584276,+!p1@NR4A3!0.81!12.94!NR4A3;;chr11:34663913..34663945,+!p6@EHF!0.81!5.39!EHF;;chr5:170736216..170736238,+!p2@TLX3!0.80!5.26!TLX3;;chr1:151804244..151804310,-!p1@RORC!0.79!5.12!RORC;;chr1:8938709..8938720,-!p3@ENO1!0.78!267.24!ENO1;;chr17:26697276..26697303,-!p2@SEBOX,p2@VTN!0.78!4.99!SEBOX;;chr6:31126291..31126399,+!p1@TCF19!0.77!51.37!TCF19;;chr9:102584159..102584174,+!p2@NR4A3!0.76!9.03!NR4A3;;chr7:27224842..27224872,-!p1@HOXA11!0.76!4.72!HOXA11;;chr17:8027418..8027432,-!p1@HES7!0.76!4.72!HES7;;chr6:10412392..10412409,-!p4@TFAP2A!0.75!5.39!TFAP2A;;chr13:73633131..73633149,+!p1@KLF5!0.74!53.66!KLF5;;chr12:2986275..2986363,-!p1@FOXM1!0.74!49.89!FOXM1;;chr12:72056800..72056834,+!p1@THAP2!0.74!6.34!THAP2;;chr11:34664014..34664045,+!p4@EHF!0.73!4.31!EHF;;chr17:46688334..46688385,-!p1@HOXB7!0.72!6.47!HOXB7;;chrX:107018969..107019024,-!p6@TSC22D3!0.72!6.07!TSC22D3;;chr21:38071430..38071456,+!p1@SIM2!0.71!4.18!SIM2;;chr2:157189180..157189290,-!p1@NR4A2!0.70!23.33!NR4A2;;chr1:935398..935465,-!p2@HES4!0.70!9.03!HES4;;chr6:126240490..126240501,+!p11@NCOA7!0.70!4.04!NCOA7;;chr16:29818199..29818216,+!p11@MAZ!0.69!6.88!MAZ;;chr10:104155659..104155676,+!p4@NFKB2!0.69!4.99!NFKB2;;chrX:107019163..107019179,-!p7@TSC22D3!0.69!4.58!TSC22D3;;chr20:42295745..42295765,+!p1@MYBL2!0.68!70.79!MYBL2;;chr12:3068544..3068597,+!p1@TEAD4!0.68!25.75!TEAD4;;chr12:54393880..54393962,+!p1@HOXC9!0.68!3.78!HOXC9;;chr2:45236540..45236577,-!p1@SIX2!0.67!3.64!SIX2;;chr20:42295713..42295738,+!p2@MYBL2!0.66!24.27!MYBL2;;chr17:41277372..41277418,-!p1@BRCA1!0.65!14.43!BRCA1;;chr1:45805872..45805900,+!p2@TOE1!0.65!9.44!TOE1;;chr3:69915369..69915381,+!p4@MITF!0.65!3.51!MITF;;chr12:54379029..54379057,+!p2@HOXC10!0.65!3.51!HOXC10;;chr8:145669791..145669834,-!p1@TONSL!0.64!11.06!TONSL;;chr15:67418119..67418162,+!p5@SMAD3!0.64!3.78!SMAD3;;chr6:10415263..10415274,-!p8@TFAP2A!0.64!3.37!TFAP2A;;chr12:54332608..54332636,+!p1@HOXC13!0.64!3.37!HOXC13;;chr12:7079780..7079791,-!p2@PHB2!0.63!19.96!PHB2;;chr1:180199393..180199426,+!p1@LHX4!0.63!3.24!LHX4;;chr3:12330560..12330579,+!p1@PPARG!0.61!3.64!PPARG;;chr17:46806067..46806097,-!p1@HOXB13!0.61!3.10!HOXB13;;chr15:90294062..90294079,-!p2@MESP1!0.60!2.97!MESP1;;chr10:28034739..28034756,-!p1@MKX!0.60!2.97!MKX;;chr21:38071403..38071428,+!p2@SIM2!0.60!2.97!SIM2;;chr3:141087393..141087426,+!p3@ZBTB38!0.58!13.21!ZBTB38;;chr12:80084737..80084763,-!p3@PAWR!0.58!12.54!PAWR;;chr12:72056773..72056796,+!p3@THAP2!0.58!3.91!THAP2;;chrX:131622958..131622978,-!p3@MBNL3!0.58!3.78!MBNL3;;chr7:27213893..27213954,-!p1@HOXA10!0.58!2.83!HOXA10;;chr17:46687935..46687950,-!p3@HOXB7!0.58!2.83!HOXB7;;chr17:46806098..46806118,-!p3@HOXB13!0.58!2.83!HOXB13;;chr11:3400340..3400422,-!p1@ZNF195!0.57!52.99!ZNF195;;chrX:70503529..70503549,+!p2@NONO!0.57!17.66!NONO;;chr22:42229210..42229229,+!p3@SREBF2!0.57!7.42!SREBF2;;chr1:247171316..247171336,-!p3@ZNF695!0.57!4.45!ZNF695;;chr14:37131058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| ||
|ffid_belonging_in_development=UBERON:0008947,UBERON:0002532,UBERON:0006595,UBERON:0010316 | |||
| | |||
|fonse_cell_line=FF:0101120 | |fonse_cell_line=FF:0101120 | ||
|fonse_cell_line_closure=FF:0101120 | |fonse_cell_line_closure=FF:0101120 | ||
Line 66: | Line 40: | ||
|fonse_treatment=FF:0000625,FF:0000632,FF:0000639,FF:0011134,FF:11894-125E4 | |fonse_treatment=FF:0000625,FF:0000632,FF:0000639,FF:0011134,FF:11894-125E4 | ||
|fonse_treatment_closure=FF:0000625,FF:0000632,FF:0000639,FF:0011134,FF:11894-125E4 | |fonse_treatment_closure=FF:0000625,FF:0000632,FF:0000639,FF:0011134,FF:11894-125E4 | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/Hep-2%2520cells%2520treated%2520with%2520Streptococci%2520strain%2520JRS4%252c%2520biol_rep1.CNhs13478.11894-125E4.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/Hep-2%2520cells%2520treated%2520with%2520Streptococci%2520strain%2520JRS4%252c%2520biol_rep1.CNhs13478.11894-125E4.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/Hep-2%2520cells%2520treated%2520with%2520Streptococci%2520strain%2520JRS4%252c%2520biol_rep1.CNhs13478.11894-125E4.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/Hep-2%2520cells%2520treated%2520with%2520Streptococci%2520strain%2520JRS4%252c%2520biol_rep1.CNhs13478.11894-125E4.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/Hep-2%2520cells%2520treated%2520with%2520Streptococci%2520strain%2520JRS4%252c%2520biol_rep1.CNhs13478.11894-125E4.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11894-125E4 | |||
|is_a=EFO:0002091;;FF:0011134 | |||
|is_obsolete= | |||
|library_id=CNhs13478 | |||
|library_id_phase_based=2:CNhs13478 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11894 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11894 | |||
|name=Hep-2 cells treated with Streptococci strain JRS4, biol_rep1 | |||
|namespace= | |namespace= | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs13478,LSID1024,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,0.12833782787131,0,0.0702426519956615,0.0125168362087064,0,0,0,0,0,0,0,0,0,0,0,0.103688332502163,0,0.135332847609268,0,0,0,0,0,-0.0979578962680575,0,0,-0.029268257276699,0,0,0,0,0,0,0,0,0,0,0.0549313087713622,0,-0.0268622977138213,0,0,0,0,0,0,0,0,0.0307162876585279,0,0,0,0,0,-0.00455718357331138,0,-0.0420610524712429,0,0,-0.0424123184417347,0,0,0,0,0,0,0,0,0.0549313087713622,0,0,0,0,0,0,0,0,-0.0108185828645783,0,0,0,0,0,-0.0421896019330941,-0.25855095394894,0,0,0,-0.133775594511865,-0.0255394382801245,0,0,0.121130848582978,0,-0.0431040424663442,-0.0265791688266786,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.6450147999327,0.103688332502163,0,0,0.064441508159659,0.016813966868179,0,0,0,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0,-0.0431040424663442,0,0,0,0.0549313087713622,0,0,0,0,0,0,0,-0.192247566514202,0,-0.370397886249845,0.0802809214249613,0.0274656543856811,0,0.139416303651747,0,0.0549313087713622,0,0,0.147519864883055,0,0,0.103688332502163,0,-0.128119866952565,0,0.0971073132937405,0,0,0,0,-0.0186252810838506,0.0396037193033447,0,-0.062360029175293,-0.0683442610773682,0,0,0,0,0.19471505987748,0,-0.0659481750223784,0.357055596600028,-0.221611588102807,-0.539221015278156,-0.000781188009819765,0,0,0,-0.619768109936715,0.264972677015415,0,0,-0.121779851751874,-0.181349618560659,0,0,-0.391044581551635,0,-0.124035290457837,0.107864849656405,0,0.304075494589569,0,0,0,0,0,0,0,0,0,0,0,-0.0574934668214365,-0.0695529469816294,0.074989692581857,0,0.257435649697339,0,-0.340709034263641,0,0,0.0872566396011435,-0.247047680794695,-0.054329484806826,-0.257635521023069,0,-0.247458418238551,-0.190797582430299,-0.40981816598622,-0.37875733113518,-0.147401849371139,-0.189981719549847,0,-0.25855095394894,-0.468491162275021,-0.0537439140735772,-0.332456718465467,-0.0807325688623707,-0.299414291959495,-0.0968437401776236,0,0,0,-0.152241300891951,0,0,0.108269616872044,-0.245377894142116,-0.198247829202821,-0.437852854966897,0.351921792909739,0.146250607715106,-0.0120668740709895,0.00310634266111565,0,-0.17191433610294,-0.0545545862774666,0,-0.087969206950705,-0.0228515835871651,0.402367964077657,-0.0641572709342229,0,-0.113221464402478,0.155451802871065,0,-0.249734097629957,-0.175697988346934,0,-0.171678281080124,-0.321341581174073,0,0,0.085639983624599,0,0,0.415578926304885,-0.25083628507247,-0.177924252784183,0,-0.134348315866666,0.0492588943069682,0.346282968806319,0,-0.231042187052647,0.055264888086534,-0.150554287478237,-0.203471657008284,0,-0.04019160991051,-0.144992966703657,-0.0174708314559474,-0.198598741443304,-0.00351551804046298,-0.147107924463656,-0.290415040974616,-0.133775594511865,-0.190555533441409,-0.123646077109975,0.135669231473145,-0.179573461694115,-0.88354475051838,0.0348123907128697,-0.119332023725769,-0.336176367382168,0,-0.538389719975463,0,0.108314134352679,0,-0.200967595638295,-0.0229564797950529,-0.215493310632253,0.205465589262357,0,-0.426624067316346,-0.085274997291202,0,0,0,0,0.0734289806137939,0.227395411664386,-0.0641305629815337,-0.111523802293514,0,-0.532644508692317,0,0,0.014991246312694,0.109599912437363,0,-0.00137072135513553,-0.0108185828645783,-0.233460043786792,-0.0122827409327707,0,0,0.160021507345798,0,0.103688332502163,0.470396863395544,0,-0.472263459075578,-0.198395032715393,-0.169593580208354,-0.108622809454255,0,0,0.0799078837321638,0,-0.312127189716061,0,0,0.00267463101796805,0,0,0,0.0549313087713622,-0.0346949479447015,0,0,0,0,0,0,-0.0772891223539179,-0.150939660928168,-0.009757380014696,0,-0.169534264126226,0,0,0,0,0,0,0,0,0.0151839444683215,-0.056253955557224,-0.068086106905058,0,0,0,0,0.102058064285516,-0.203236562094724,0.103688332502163,0.0554676818969608,0,0,0,0,-0.0861409897892114,0,0,0,0,-0.00279914828230179,-0.010580198051158,0,0,0,-0.0531583376533572,0,0,0,0,-0.216538014840054,0,0,0.1355171359358,0,-0.140091873430192,0.065937985336214,0,0.332157163602467,-0.283839542468358,0.202937671751813,0,0,-0.0375510678414544,0,0,0.0253890885180519,0.00217530901028767,0,0,0,0,0,0,0,0.187330388394593,0.00948155154867755,0,0,0,0,0,0,0,0.147519864883055,0,0,0,-0.0905232472555477,0.131572007289923,0,0,0,0,0,0.0274656543856811,0,0.121403337369475,0.205553204650648,0,0,0,0,0,0.0549313087713622,0,0,-0.0534603288875324,0,0,0.0274656543856811,0,0,-0.0420610524712429,0,0,0,0,-0.0298976363539495,0,0,-0.0535660682450808,0,0,0,0,0,0,0,0,0,0,0,0,0,0.194462380803543,0.160597768456517,0,0,0,0,0,0,0,0.0702426519956615,0,0.0549313087713622,0,0,1.79796075304772,0,0,0,-0.104796384789156,0,0.12833782787131,0,0,0.77733679315989,0,0,0,0,0,0,0,0.0549313087713622,0,0,0,0,0,0,0,0.101225586827209,0,0,-0.356715567336318,0,-0.285473239701733,0.0528280230363161,0,0,-0.0883004236541935,0,0,0,0,0,0,-0.00387476964284595,0,0,0,0,0,0,0,0.0274656543856811,0,0,0,0,0,0,0,0,0,0,0.103688332502163,0,0,0,0,0,0,-0.00739238941940725,0,0,0,0,0,0,0,-0.0979578962680575,0,0,-0.0127229891637633,0,0,0,0,0,0,-0.0354209130399175,0.0795149678150845,-0.120608933339084,0,0,0,-0.00254140623137335,0,0,0,0,0.25100407942009,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.135332847609268,0,0,0,0,0,0,0,0,0,0,0,0,0.0274656543856811,0,0,0,0,0,0.125604098692609,0,0,0,0,0,0,0,0,0,0.0518441662510815,0,0,0,0,0,0,-0.0340113632754165,0,0,0,0.0549313087713622,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0236698642335249,0,0,0,-0.10939789715488,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.640559215824414,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0549313087713622,0,0,0,0.0551139286073158,0,0,0,0,0,0,0,0,0.0549313087713622,0,0,0,0,0.0554662572631091,0,0.0193117002721362,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.20542809231396,0,0,0,0,0.00729419811044339,0,0.172537975100876,0,0,0,0,0,0,0,0,0.103688332502163,0,0,0,0,0,0,0,0,0,0,-0.198679299517143,0,0,-0.02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| |||
|rna_box=125 | |||
|rna_catalog_number= | |||
|rna_concentration=0.86368 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number=2a | |||
|rna_od260/230=1.47 | |||
|rna_od260/280=2.03 | |||
|rna_position=E4 | |||
|rna_rin=9.5 | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=1.25E+06 | |||
|rna_weight_ug=10 | |||
|sample_age=56 | |||
|sample_category=cell lines | |||
|sample_cell_catalog= | |||
|sample_cell_line=Hep-2 | |||
|sample_cell_lot= | |||
|sample_cell_type=unclassifiable | |||
|sample_collaboration=Christine Wells (University of Queensland) | |||
|sample_company= | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=epidermoid carcinoma | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;2.26316263140678e-257!GO:0005737;cytoplasm;2.4482451449573e-210!GO:0043226;organelle;1.56555855509781e-206!GO:0043229;intracellular organelle;6.875169877845e-206!GO:0043227;membrane-bound organelle;1.71398876876492e-205!GO:0043231;intracellular membrane-bound organelle;1.88712905673226e-205!GO:0044422;organelle part;6.91894786589458e-178!GO:0044446;intracellular organelle part;8.6488865103177e-176!GO:0044444;cytoplasmic part;6.47091334445581e-156!GO:0032991;macromolecular complex;7.74820975329099e-123!GO:0030529;ribonucleoprotein complex;2.65551895654853e-103!GO:0005739;mitochondrion;1.09192354010043e-100!GO:0044237;cellular metabolic process;5.26583601910792e-93!GO:0043233;organelle lumen;1.88771978626489e-89!GO:0031974;membrane-enclosed lumen;1.88771978626489e-89!GO:0044238;primary metabolic process;2.187943200221e-89!GO:0044428;nuclear part;5.03112359694792e-88!GO:0003723;RNA binding;5.24037535797883e-83!GO:0005634;nucleus;2.94979640869661e-75!GO:0043170;macromolecule metabolic process;6.24268192202838e-75!GO:0005515;protein binding;1.30338938134168e-69!GO:0044429;mitochondrial part;2.75261394838793e-65!GO:0005840;ribosome;1.06717961106202e-62!GO:0006396;RNA processing;2.20228067414076e-62!GO:0043234;protein complex;2.20228067414076e-62!GO:0006412;translation;2.97252947028015e-61!GO:0031090;organelle membrane;3.20057361246757e-59!GO:0031967;organelle envelope;4.68887868801124e-57!GO:0031975;envelope;7.62935891436014e-57!GO:0003735;structural constituent of ribosome;2.08417494273153e-54!GO:0044249;cellular biosynthetic process;3.78967665682682e-54!GO:0009058;biosynthetic process;2.38366148268242e-53!GO:0031981;nuclear lumen;3.22888596775306e-51!GO:0016043;cellular component organization and biogenesis;9.241233286654e-49!GO:0033279;ribosomal subunit;1.15296818156088e-47!GO:0019538;protein metabolic process;2.8236607496328e-46!GO:0015031;protein transport;3.55076445891236e-45!GO:0005829;cytosol;2.86669262828377e-44!GO:0033036;macromolecule localization;4.08700892265368e-44!GO:0043228;non-membrane-bound organelle;7.67739880041735e-44!GO:0043232;intracellular non-membrane-bound organelle;7.67739880041735e-44!GO:0009059;macromolecule biosynthetic process;1.58411886400997e-43!GO:0006259;DNA metabolic process;6.41382510943728e-43!GO:0016071;mRNA metabolic process;3.43909665658559e-42!GO:0005740;mitochondrial envelope;4.19248862703148e-42!GO:0008380;RNA splicing;3.9809793616844e-41!GO:0045184;establishment of protein localization;5.51586705954304e-41!GO:0044260;cellular macromolecule metabolic process;1.85265432547349e-40!GO:0044267;cellular protein metabolic process;2.72901188328687e-40!GO:0008104;protein localization;3.28153407114497e-40!GO:0019866;organelle inner membrane;6.96628323833643e-40!GO:0031966;mitochondrial membrane;1.55277122382021e-39!GO:0006397;mRNA processing;2.12325789832569e-38!GO:0005743;mitochondrial inner membrane;8.69321641394996e-38!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.00950354330218e-37!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.98014324116768e-37!GO:0065003;macromolecular complex assembly;1.25725735224985e-36!GO:0043283;biopolymer metabolic process;1.38624873397266e-36!GO:0006996;organelle organization and biogenesis;1.21771069957147e-35!GO:0046907;intracellular transport;2.89325652338019e-35!GO:0010467;gene expression;1.18941220665692e-33!GO:0005830;cytosolic ribosome (sensu Eukaryota);4.21878930895755e-32!GO:0007049;cell cycle;4.81909526194983e-32!GO:0022607;cellular component assembly;8.42081563013055e-32!GO:0006886;intracellular protein transport;2.3893645080305e-30!GO:0005681;spliceosome;4.12653586958034e-30!GO:0005654;nucleoplasm;3.59441624435935e-29!GO:0031980;mitochondrial lumen;9.07832179002485e-29!GO:0005759;mitochondrial matrix;9.07832179002485e-29!GO:0000166;nucleotide binding;4.48153739207125e-27!GO:0044445;cytosolic part;9.73534142085659e-27!GO:0006119;oxidative phosphorylation;9.94309169234823e-27!GO:0044455;mitochondrial membrane part;1.64931313226637e-26!GO:0006974;response to DNA damage stimulus;6.56133275130162e-26!GO:0015934;large ribosomal subunit;8.40727475588845e-26!GO:0005730;nucleolus;8.49373666774244e-26!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.59786435254268e-25!GO:0016462;pyrophosphatase activity;1.93634833820203e-25!GO:0016817;hydrolase activity, acting on acid anhydrides;2.48378557080419e-25!GO:0017111;nucleoside-triphosphatase activity;2.1986157648465e-24!GO:0000278;mitotic cell cycle;6.28091621126086e-24!GO:0022402;cell cycle process;7.49357913648008e-24!GO:0051649;establishment of cellular localization;1.14861992487743e-23!GO:0051641;cellular localization;1.35557872716854e-23!GO:0005694;chromosome;2.53014570825032e-23!GO:0015935;small ribosomal subunit;4.26523759245695e-23!GO:0044451;nucleoplasm part;5.67536327256246e-23!GO:0051186;cofactor metabolic process;1.04069416298547e-22!GO:0006281;DNA repair;8.18524647492817e-22!GO:0044427;chromosomal part;8.88489762812814e-22!GO:0006457;protein folding;1.24578698914621e-21!GO:0012505;endomembrane system;1.92653948583064e-21!GO:0005783;endoplasmic reticulum;5.26619590826892e-21!GO:0016874;ligase activity;1.32683209046414e-20!GO:0005746;mitochondrial respiratory chain;3.73212844199215e-20!GO:0022618;protein-RNA complex assembly;7.37095867719236e-20!GO:0006260;DNA replication;8.64363771112136e-20!GO:0009719;response to endogenous stimulus;1.24367480726035e-19!GO:0005761;mitochondrial ribosome;1.36758919807552e-19!GO:0000313;organellar ribosome;1.36758919807552e-19!GO:0022403;cell cycle phase;2.83960746924922e-19!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;4.99819150482578e-19!GO:0003676;nucleic acid binding;6.66146111722992e-19!GO:0042254;ribosome biogenesis and assembly;1.26289961540594e-18!GO:0017076;purine nucleotide binding;1.88512346577858e-18!GO:0032553;ribonucleotide binding;2.23222312302791e-18!GO:0032555;purine ribonucleotide binding;2.23222312302791e-18!GO:0044432;endoplasmic reticulum part;2.64722091388683e-18!GO:0006732;coenzyme metabolic process;2.97550405015029e-18!GO:0000502;proteasome complex (sensu Eukaryota);3.93457777737666e-18!GO:0050136;NADH dehydrogenase (quinone) activity;4.51593415091609e-18!GO:0003954;NADH dehydrogenase activity;4.51593415091609e-18!GO:0008137;NADH dehydrogenase (ubiquinone) activity;4.51593415091609e-18!GO:0000087;M phase of mitotic cell cycle;7.37118821581058e-18!GO:0007067;mitosis;1.41922368708975e-17!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);3.50852061791226e-17!GO:0008135;translation factor activity, nucleic acid binding;3.75125031224472e-17!GO:0044248;cellular catabolic process;3.84244618045512e-17!GO:0044265;cellular macromolecule catabolic process;9.49286239166894e-17!GO:0005524;ATP binding;2.40900803960675e-16!GO:0042775;organelle ATP synthesis coupled electron transport;2.40900803960675e-16!GO:0042773;ATP synthesis coupled electron transport;2.40900803960675e-16!GO:0016887;ATPase activity;2.56987837292905e-16!GO:0032559;adenyl ribonucleotide binding;2.8136239340573e-16!GO:0051276;chromosome organization and biogenesis;3.31512134539501e-16!GO:0030554;adenyl nucleotide binding;3.8082177325252e-16!GO:0006605;protein targeting;4.0905682099105e-16!GO:0006512;ubiquitin cycle;4.51201613177544e-16!GO:0042623;ATPase activity, coupled;4.70415192888393e-16!GO:0030964;NADH dehydrogenase complex (quinone);4.71795121817395e-16!GO:0045271;respiratory chain complex I;4.71795121817395e-16!GO:0005747;mitochondrial respiratory chain complex I;4.71795121817395e-16!GO:0005635;nuclear envelope;1.3227590348137e-15!GO:0051301;cell division;1.39221933950041e-15!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.48224820884841e-15!GO:0006399;tRNA metabolic process;1.5652303780218e-15!GO:0048770;pigment granule;1.7287504349704e-15!GO:0042470;melanosome;1.7287504349704e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.89043041686449e-15!GO:0044453;nuclear membrane part;3.26504448851662e-15!GO:0051603;proteolysis involved in cellular protein catabolic process;4.05347550387806e-15!GO:0000279;M phase;4.10391645600622e-15!GO:0051082;unfolded protein binding;4.62248330204217e-15!GO:0019941;modification-dependent protein catabolic process;6.8112523557565e-15!GO:0043632;modification-dependent macromolecule catabolic process;6.8112523557565e-15!GO:0009055;electron carrier activity;8.09506789598335e-15!GO:0000398;nuclear mRNA splicing, via spliceosome;1.01640331793458e-14!GO:0000375;RNA splicing, via transesterification reactions;1.01640331793458e-14!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.01640331793458e-14!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.05178083399429e-14!GO:0044257;cellular protein catabolic process;1.1829815175578e-14!GO:0031965;nuclear membrane;1.49030819511117e-14!GO:0006511;ubiquitin-dependent protein catabolic process;1.61790980464091e-14!GO:0042175;nuclear envelope-endoplasmic reticulum network;2.25006390463859e-14!GO:0005789;endoplasmic reticulum membrane;5.63680527930201e-14!GO:0008134;transcription factor binding;9.54949885823602e-14!GO:0009057;macromolecule catabolic process;9.61716201333386e-14!GO:0043285;biopolymer catabolic process;1.02729361651973e-13!GO:0003743;translation initiation factor activity;2.51563971124974e-13!GO:0006325;establishment and/or maintenance of chromatin architecture;4.78876241370349e-13!GO:0006364;rRNA processing;5.14266280108673e-13!GO:0005643;nuclear pore;5.70583202953931e-13!GO:0009259;ribonucleotide metabolic process;5.86482692196828e-13!GO:0006413;translational initiation;6.83534783216969e-13!GO:0012501;programmed cell death;6.83534783216969e-13!GO:0006915;apoptosis;1.01181216506206e-12!GO:0051726;regulation of cell cycle;1.0510091599855e-12!GO:0051188;cofactor biosynthetic process;1.13711674945397e-12!GO:0000074;regulation of progression through cell cycle;1.20989048523964e-12!GO:0016072;rRNA metabolic process;1.23453010772762e-12!GO:0006163;purine nucleotide metabolic process;1.55688242565074e-12!GO:0006323;DNA packaging;1.58137935512314e-12!GO:0000785;chromatin;1.59452524987637e-12!GO:0065002;intracellular protein transport across a membrane;1.73502418232539e-12!GO:0016192;vesicle-mediated transport;2.46049913563777e-12!GO:0048193;Golgi vesicle transport;2.52610663542442e-12!GO:0006913;nucleocytoplasmic transport;2.54975593114263e-12!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;4.87025902106671e-12!GO:0051169;nuclear transport;8.55151123646674e-12!GO:0009150;purine ribonucleotide metabolic process;1.83931979308372e-11!GO:0050657;nucleic acid transport;1.97173238592656e-11!GO:0051236;establishment of RNA localization;1.97173238592656e-11!GO:0050658;RNA transport;1.97173238592656e-11!GO:0030163;protein catabolic process;1.99710130337682e-11!GO:0008219;cell death;2.0921737559821e-11!GO:0016265;death;2.0921737559821e-11!GO:0004386;helicase activity;2.32324601089493e-11!GO:0006403;RNA localization;2.38596953998397e-11!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;2.4137636350901e-11!GO:0009260;ribonucleotide biosynthetic process;3.29873231717771e-11!GO:0006164;purine nucleotide biosynthetic process;3.95399565991044e-11!GO:0016604;nuclear body;4.67683219716878e-11!GO:0046930;pore complex;5.06571926449911e-11!GO:0016879;ligase activity, forming carbon-nitrogen bonds;5.35940116798298e-11!GO:0016491;oxidoreductase activity;5.81768327048419e-11!GO:0006461;protein complex assembly;6.32902366250408e-11!GO:0016070;RNA metabolic process;7.74426343196987e-11!GO:0008026;ATP-dependent helicase activity;8.17684971266209e-11!GO:0006446;regulation of translational initiation;8.80547848058978e-11!GO:0009117;nucleotide metabolic process;1.08198837889229e-10!GO:0006333;chromatin assembly or disassembly;1.12983103569482e-10!GO:0007005;mitochondrion organization and biogenesis;1.2663215907324e-10!GO:0009060;aerobic respiration;1.26792300759694e-10!GO:0009108;coenzyme biosynthetic process;1.32893710023369e-10!GO:0005794;Golgi apparatus;1.40190002858965e-10!GO:0009141;nucleoside triphosphate metabolic process;2.14815259859732e-10!GO:0065004;protein-DNA complex assembly;2.15595003683998e-10!GO:0009199;ribonucleoside triphosphate metabolic process;2.30012077328765e-10!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;2.42573814989863e-10!GO:0008565;protein transporter activity;3.22074352070631e-10!GO:0043412;biopolymer modification;4.53057494600078e-10!GO:0009152;purine ribonucleotide biosynthetic process;4.58983321580565e-10!GO:0045333;cellular respiration;5.15381249817679e-10!GO:0009205;purine ribonucleoside triphosphate metabolic process;5.69724422615294e-10!GO:0009144;purine nucleoside triphosphate metabolic process;5.69724422615294e-10!GO:0009056;catabolic process;7.20314458702396e-10!GO:0016779;nucleotidyltransferase activity;1.00275630541786e-09!GO:0015986;ATP synthesis coupled proton transport;1.07449676017401e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.07449676017401e-09!GO:0006261;DNA-dependent DNA replication;1.08255000971785e-09!GO:0006366;transcription from RNA polymerase II promoter;1.16257394630951e-09!GO:0030532;small nuclear ribonucleoprotein complex;1.16865190291576e-09!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.17730797263263e-09!GO:0051028;mRNA transport;1.20924675891749e-09!GO:0016787;hydrolase activity;1.25583484475176e-09!GO:0008639;small protein conjugating enzyme activity;1.65825601487047e-09!GO:0017038;protein import;1.66776541733072e-09!GO:0009142;nucleoside triphosphate biosynthetic process;2.11280921352485e-09!GO:0009201;ribonucleoside triphosphate biosynthetic process;2.11280921352485e-09!GO:0046034;ATP metabolic process;2.592513210743e-09!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;2.83860331668791e-09!GO:0004812;aminoacyl-tRNA ligase activity;2.83860331668791e-09!GO:0016875;ligase activity, forming carbon-oxygen bonds;2.83860331668791e-09!GO:0003697;single-stranded DNA binding;3.1535804214006e-09!GO:0043566;structure-specific DNA binding;4.28680453552583e-09!GO:0004842;ubiquitin-protein ligase activity;4.78654479013844e-09!GO:0019787;small conjugating protein ligase activity;4.78654479013844e-09!GO:0043038;amino acid activation;4.78654479013844e-09!GO:0006418;tRNA aminoacylation for protein translation;4.78654479013844e-09!GO:0043039;tRNA aminoacylation;4.78654479013844e-09!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;5.24214351312624e-09!GO:0009145;purine nucleoside triphosphate biosynthetic process;5.24214351312624e-09!GO:0019829;cation-transporting ATPase activity;7.37430183675604e-09!GO:0006099;tricarboxylic acid cycle;8.90900899611582e-09!GO:0046356;acetyl-CoA catabolic process;8.90900899611582e-09!GO:0016607;nuclear speck;1.11653827272078e-08!GO:0005793;ER-Golgi intermediate compartment;1.35533690322288e-08!GO:0006084;acetyl-CoA metabolic process;1.37653961179813e-08!GO:0042981;regulation of apoptosis;1.5993400588417e-08!GO:0000775;chromosome, pericentric region;1.74825838032141e-08!GO:0016881;acid-amino acid ligase activity;1.80702816369593e-08!GO:0016469;proton-transporting two-sector ATPase complex;1.83239079763088e-08!GO:0043067;regulation of programmed cell death;1.86015276285608e-08!GO:0015078;hydrogen ion transmembrane transporter activity;1.86015276285608e-08!GO:0006754;ATP biosynthetic process;1.99924430317881e-08!GO:0006753;nucleoside phosphate metabolic process;1.99924430317881e-08!GO:0006334;nucleosome assembly;2.12654388625927e-08!GO:0003712;transcription cofactor activity;3.65359078893348e-08!GO:0006464;protein modification process;4.17100247201047e-08!GO:0031497;chromatin assembly;4.26106493078004e-08!GO:0051325;interphase;4.29800002818337e-08!GO:0006752;group transfer coenzyme metabolic process;4.58062146242995e-08!GO:0005819;spindle;6.62062197520576e-08!GO:0006091;generation of precursor metabolites and energy;7.09417281591283e-08!GO:0051329;interphase of mitotic cell cycle;7.23509193261841e-08!GO:0016740;transferase activity;7.90731252795193e-08!GO:0008033;tRNA processing;1.22568290869181e-07!GO:0005657;replication fork;1.2349740549594e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.68758591460232e-07!GO:0051187;cofactor catabolic process;1.77983942148587e-07!GO:0005768;endosome;2.02179023247357e-07!GO:0005762;mitochondrial large ribosomal subunit;2.07794254022572e-07!GO:0000315;organellar large ribosomal subunit;2.07794254022572e-07!GO:0030120;vesicle coat;2.19021342093946e-07!GO:0030662;coated vesicle membrane;2.19021342093946e-07!GO:0009109;coenzyme catabolic process;2.61483436599312e-07!GO:0006888;ER to Golgi vesicle-mediated transport;2.72308722821292e-07!GO:0045259;proton-transporting ATP synthase complex;2.78556215867121e-07!GO:0008094;DNA-dependent ATPase activity;3.02148511323775e-07!GO:0005839;proteasome core complex (sensu Eukaryota);3.66186307332318e-07!GO:0006916;anti-apoptosis;4.54665803176304e-07!GO:0043623;cellular protein complex assembly;4.68803690660957e-07!GO:0043687;post-translational protein modification;4.98506708520947e-07!GO:0003899;DNA-directed RNA polymerase activity;4.99985661242968e-07!GO:0008654;phospholipid biosynthetic process;5.67379551908779e-07!GO:0043069;negative regulation of programmed cell death;5.93791159197146e-07!GO:0051246;regulation of protein metabolic process;6.34483998313917e-07!GO:0016568;chromatin modification;7.36027433603652e-07!GO:0016853;isomerase activity;7.59409766857679e-07!GO:0000245;spliceosome assembly;8.13175476694597e-07!GO:0043066;negative regulation of apoptosis;8.79233117804206e-07!GO:0048475;coated membrane;8.79233117804206e-07!GO:0030117;membrane coat;8.79233117804206e-07!GO:0032446;protein modification by small protein conjugation;1.13183356132444e-06!GO:0000075;cell cycle checkpoint;1.41320675349855e-06!GO:0015630;microtubule cytoskeleton;1.4523338387318e-06!GO:0051170;nuclear import;1.6801534640897e-06!GO:0005667;transcription factor complex;1.70649963732681e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.73748268047849e-06!GO:0016567;protein ubiquitination;1.81303648624918e-06!GO:0004298;threonine endopeptidase activity;2.09429694634526e-06!GO:0007051;spindle organization and biogenesis;2.09429694634526e-06!GO:0051427;hormone receptor binding;2.28371819419086e-06!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;2.36019228053503e-06!GO:0006082;organic acid metabolic process;2.48134156800242e-06!GO:0048523;negative regulation of cellular process;2.6042121960877e-06!GO:0019752;carboxylic acid metabolic process;2.63201423428167e-06!GO:0000314;organellar small ribosomal subunit;2.74184517347359e-06!GO:0005763;mitochondrial small ribosomal subunit;2.74184517347359e-06!GO:0003724;RNA helicase activity;2.88804898251616e-06!GO:0009165;nucleotide biosynthetic process;2.91966609978e-06!GO:0007249;I-kappaB kinase/NF-kappaB cascade;3.02925270348528e-06!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;3.32948347062053e-06!GO:0000079;regulation of cyclin-dependent protein kinase activity;4.53511229007691e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;5.31823523088155e-06!GO:0035257;nuclear hormone receptor binding;5.4596070075445e-06!GO:0006613;cotranslational protein targeting to membrane;5.81199807482615e-06!GO:0005788;endoplasmic reticulum lumen;6.22917030260274e-06!GO:0006606;protein import into nucleus;6.36009495044549e-06!GO:0000151;ubiquitin ligase complex;8.36483375503833e-06!GO:0006302;double-strand break repair;8.36483375503833e-06!GO:0006626;protein targeting to mitochondrion;8.6696955687979e-06!GO:0044452;nucleolar part;8.87420099860016e-06!GO:0006414;translational elongation;9.1810419706624e-06!GO:0005773;vacuole;9.24542094591431e-06!GO:0051168;nuclear export;1.07954138329337e-05!GO:0031324;negative regulation of cellular metabolic process;1.29897787996479e-05!GO:0003924;GTPase activity;1.47460896342887e-05!GO:0046474;glycerophospholipid biosynthetic process;1.67063688019303e-05!GO:0046483;heterocycle metabolic process;1.79762968541019e-05!GO:0005813;centrosome;1.91111798115065e-05!GO:0008168;methyltransferase activity;2.03922926488722e-05!GO:0045454;cell redox homeostasis;2.05287175703856e-05!GO:0016741;transferase activity, transferring one-carbon groups;2.2167533083792e-05!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;2.32234485475475e-05!GO:0015980;energy derivation by oxidation of organic compounds;2.34511468463864e-05!GO:0006839;mitochondrial transport;2.81535909011589e-05!GO:0003682;chromatin binding;2.84130157479909e-05!GO:0005770;late endosome;2.92343852692561e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;3.01049916875637e-05!GO:0015399;primary active transmembrane transporter activity;3.01049916875637e-05!GO:0044440;endosomal part;3.01049916875637e-05!GO:0010008;endosome membrane;3.01049916875637e-05!GO:0016859;cis-trans isomerase activity;3.64447865116399e-05!GO:0005815;microtubule organizing center;3.68522271927638e-05!GO:0000786;nucleosome;3.82535928517855e-05!GO:0043021;ribonucleoprotein binding;3.87009547768004e-05!GO:0003713;transcription coactivator activity;4.17412576776419e-05!GO:0000323;lytic vacuole;4.17412576776419e-05!GO:0005764;lysosome;4.17412576776419e-05!GO:0007088;regulation of mitosis;4.19537908414758e-05!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;4.19537908414758e-05!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;4.21698523262162e-05!GO:0050662;coenzyme binding;4.65724445446117e-05!GO:0006950;response to stress;4.69085212253682e-05!GO:0016126;sterol biosynthetic process;4.883683840858e-05!GO:0019867;outer membrane;4.99094973438637e-05!GO:0008610;lipid biosynthetic process;5.01639178049328e-05!GO:0043681;protein import into mitochondrion;5.08981331834461e-05!GO:0006793;phosphorus metabolic process;5.32937882416799e-05!GO:0006796;phosphate metabolic process;5.32937882416799e-05!GO:0051052;regulation of DNA metabolic process;5.51573781725761e-05!GO:0030867;rough endoplasmic reticulum membrane;6.04138997785694e-05!GO:0031968;organelle outer membrane;6.40312512028906e-05!GO:0003690;double-stranded DNA binding;6.67359730034829e-05!GO:0009892;negative regulation of metabolic process;6.83244004104087e-05!GO:0006612;protein targeting to membrane;7.57446634855743e-05!GO:0048519;negative regulation of biological process;7.85362780819508e-05!GO:0005753;mitochondrial proton-transporting ATP synthase complex;8.04847780531394e-05!GO:0005852;eukaryotic translation initiation factor 3 complex;8.39464802514329e-05!GO:0000776;kinetochore;8.92308585282225e-05!GO:0008186;RNA-dependent ATPase activity;9.17803113185968e-05!GO:0046489;phosphoinositide biosynthetic process;9.78521673430947e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;9.88428131424906e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;0.000108926695408082!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000120034144894216!GO:0045786;negative regulation of progression through cell cycle;0.000124033402905558!GO:0005525;GTP binding;0.000127773965171781!GO:0006383;transcription from RNA polymerase III promoter;0.000129896401464013!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000136348197945664!GO:0006310;DNA recombination;0.00014276169856272!GO:0003684;damaged DNA binding;0.000146708532051722!GO:0007059;chromosome segregation;0.000154403589715882!GO:0005791;rough endoplasmic reticulum;0.000165846477547591!GO:0051789;response to protein stimulus;0.000181334836651058!GO:0006986;response to unfolded protein;0.000181334836651058!GO:0004527;exonuclease activity;0.000183083937495368!GO:0005798;Golgi-associated vesicle;0.000183704943353081!GO:0006695;cholesterol biosynthetic process;0.000187287141614541!GO:0030880;RNA polymerase complex;0.000235611173009715!GO:0000059;protein import into nucleus, docking;0.0002388267008775!GO:0005741;mitochondrial outer membrane;0.00024042687658889!GO:0004004;ATP-dependent RNA helicase activity;0.000257036785682097!GO:0031988;membrane-bound vesicle;0.000258992536741456!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000260351096109292!GO:0006520;amino acid metabolic process;0.000272472090834847!GO:0042802;identical protein binding;0.000286932125688325!GO:0016310;phosphorylation;0.000312040407016989!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.00032150376514154!GO:0006650;glycerophospholipid metabolic process;0.00032154214072609!GO:0004518;nuclease activity;0.000322587979849408!GO:0033116;ER-Golgi intermediate compartment membrane;0.000328299170664678!GO:0019843;rRNA binding;0.000361504170373058!GO:0043284;biopolymer biosynthetic process;0.000370589898080617!GO:0048037;cofactor binding;0.000370891479721276!GO:0044431;Golgi apparatus part;0.000376094258930366!GO:0043596;nuclear replication fork;0.000376529477451394!GO:0003678;DNA helicase activity;0.000376932954211319!GO:0016023;cytoplasmic membrane-bound vesicle;0.000403153797180544!GO:0009112;nucleobase metabolic process;0.000437708570396963!GO:0051920;peroxiredoxin activity;0.00048224855721131!GO:0008361;regulation of cell size;0.000534721588914471!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000534721588914471!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.000542814632346273!GO:0003729;mRNA binding;0.000557164457500303!GO:0001558;regulation of cell growth;0.000559286881537148!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.000590253363584528!GO:0000428;DNA-directed RNA polymerase complex;0.000590253363584528!GO:0051540;metal cluster binding;0.000608553371387812!GO:0051536;iron-sulfur cluster binding;0.000608553371387812!GO:0006275;regulation of DNA replication;0.000615063009467489!GO:0006118;electron transport;0.000619015462836534!GO:0007006;mitochondrial membrane organization and biogenesis;0.000621946602250817!GO:0005048;signal sequence binding;0.000621946602250817!GO:0031252;leading edge;0.000639853697231556!GO:0016049;cell growth;0.000639853697231556!GO:0065009;regulation of a molecular function;0.000658993741444554!GO:0016564;transcription repressor activity;0.000668094573176222!GO:0005684;U2-dependent spliceosome;0.000680535517680558!GO:0016563;transcription activator activity;0.000684147554240236!GO:0009116;nucleoside metabolic process;0.000693103045804997!GO:0048471;perinuclear region of cytoplasm;0.000716357984153972!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000724724928437071!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000724724928437071!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000724724928437071!GO:0005905;coated pit;0.000760687070328002!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.000766804929272826!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.000766804929272826!GO:0005885;Arp2/3 protein complex;0.000772851415118553!GO:0046467;membrane lipid biosynthetic process;0.000775949588346925!GO:0016363;nuclear matrix;0.000852174844905316!GO:0031072;heat shock protein binding;0.000910743693297122!GO:0006506;GPI anchor biosynthetic process;0.000957851268330068!GO:0030176;integral to endoplasmic reticulum membrane;0.00099952910733408!GO:0015992;proton transport;0.00099952910733408!GO:0016044;membrane organization and biogenesis;0.00100966418196756!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.00102659448769285!GO:0006767;water-soluble vitamin metabolic process;0.0010307062610684!GO:0031982;vesicle;0.00107798100882007!GO:0006284;base-excision repair;0.00107798100882007!GO:0032508;DNA duplex unwinding;0.001082056805263!GO:0032392;DNA geometric change;0.001082056805263!GO:0043492;ATPase activity, coupled to movement of substances;0.00113864087363581!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00115664708485719!GO:0006818;hydrogen transport;0.0011824951252881!GO:0051087;chaperone binding;0.0011974984908067!GO:0030132;clathrin coat of coated pit;0.00121042992402245!GO:0051287;NAD binding;0.0012104476370601!GO:0048487;beta-tubulin binding;0.00124521360428372!GO:0008180;signalosome;0.0013040420276094!GO:0003711;transcription elongation regulator activity;0.0013040420276094!GO:0030118;clathrin coat;0.00131973220818998!GO:0032561;guanyl ribonucleotide binding;0.00133751831527314!GO:0019001;guanyl nucleotide binding;0.00133751831527314!GO:0048500;signal recognition particle;0.00133751831527314!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00134174576009424!GO:0044262;cellular carbohydrate metabolic process;0.00136878559460461!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00140489372885407!GO:0006270;DNA replication initiation;0.00140489372885407!GO:0006405;RNA export from nucleus;0.0014744041942259!GO:0000049;tRNA binding;0.00147651452517815!GO:0016628;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;0.00150366420949893!GO:0008312;7S RNA binding;0.00157298370447295!GO:0006505;GPI anchor metabolic process;0.00158533605492873!GO:0030663;COPI coated vesicle membrane;0.00162382599310024!GO:0030126;COPI vesicle coat;0.00162382599310024!GO:0048522;positive regulation of cellular process;0.0016254965520044!GO:0035258;steroid hormone receptor binding;0.00169202532795878!GO:0007052;mitotic spindle organization and biogenesis;0.0016938516857621!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00169754861570517!GO:0030384;phosphoinositide metabolic process;0.00176214596023586!GO:0016272;prefoldin complex;0.00176918831515722!GO:0006352;transcription initiation;0.00177923069086908!GO:0031410;cytoplasmic vesicle;0.00178482643725417!GO:0008632;apoptotic program;0.00183247759948485!GO:0005758;mitochondrial intermembrane space;0.00183825016847493!GO:0006733;oxidoreduction coenzyme metabolic process;0.00185821869256194!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00188771370723182!GO:0043601;nuclear replisome;0.00194583409232106!GO:0030894;replisome;0.00194583409232106!GO:0007093;mitotic cell cycle checkpoint;0.00194806677256222!GO:0016481;negative regulation of transcription;0.00197183615759748!GO:0006497;protein amino acid lipidation;0.00197183615759748!GO:0006268;DNA unwinding during replication;0.0020004544087333!GO:0006007;glucose catabolic process;0.00217156261934171!GO:0003746;translation elongation factor activity;0.00225096532392952!GO:0008408;3'-5' exonuclease activity;0.002361742441575!GO:0005876;spindle microtubule;0.0024887501292108!GO:0008320;protein transmembrane transporter activity;0.00250120693290045!GO:0006519;amino acid and derivative metabolic process;0.00260629430949907!GO:0000086;G2/M transition of mitotic cell cycle;0.0026162831165611!GO:0000082;G1/S transition of mitotic cell cycle;0.00263188869958978!GO:0005769;early endosome;0.00267019428124691!GO:0009451;RNA modification;0.00296108831337591!GO:0003714;transcription corepressor activity;0.00301621742571767!GO:0006611;protein export from nucleus;0.00303717288254164!GO:0042393;histone binding;0.00320485308184272!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00320559660124952!GO:0015002;heme-copper terminal oxidase activity;0.00320559660124952!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00320559660124952!GO:0004129;cytochrome-c oxidase activity;0.00320559660124952!GO:0042770;DNA damage response, signal transduction;0.00324639955177704!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00324639955177704!GO:0045047;protein targeting to ER;0.00324639955177704!GO:0043065;positive regulation of apoptosis;0.00324639955177704!GO:0016251;general RNA polymerase II transcription factor activity;0.00336061768419769!GO:0051252;regulation of RNA metabolic process;0.00336061768419769!GO:0000178;exosome (RNase complex);0.0034840639233008!GO:0007243;protein kinase cascade;0.00349257573322951!GO:0000139;Golgi membrane;0.00353412702988855!GO:0006144;purine base metabolic process;0.00355925972631083!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0035769014820357!GO:0006401;RNA catabolic process;0.00366428448375099!GO:0015631;tubulin binding;0.00368947943460444!GO:0022890;inorganic cation transmembrane transporter activity;0.00374951540234858!GO:0000096;sulfur amino acid metabolic process;0.00382004537233644!GO:0019899;enzyme binding;0.00384119424626665!GO:0022884;macromolecule transmembrane transporter activity;0.00401303310898065!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.00401303310898065!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00403610912080012!GO:0043068;positive regulation of programmed cell death;0.00409843752097141!GO:0005637;nuclear inner membrane;0.00425991361829765!GO:0006595;polyamine metabolic process;0.00427284522496951!GO:0030137;COPI-coated vesicle;0.00431315374262901!GO:0000228;nuclear chromosome;0.00431315374262901!GO:0004532;exoribonuclease activity;0.00441482610409029!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00441482610409029!GO:0006417;regulation of translation;0.00441482610409029!GO:0008637;apoptotic mitochondrial changes;0.00468202251647715!GO:0030658;transport vesicle membrane;0.00469834714665799!GO:0000287;magnesium ion binding;0.00484791100198396!GO:0016408;C-acyltransferase activity;0.0050026925509753!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00536749879511757!GO:0003725;double-stranded RNA binding;0.00541096950697281!GO:0040008;regulation of growth;0.00544425967867289!GO:0008022;protein C-terminus binding;0.00562321978886213!GO:0031902;late endosome membrane;0.00607351733489576!GO:0050790;regulation of catalytic activity;0.00646723399169042!GO:0045045;secretory pathway;0.00671924380182092!GO:0016125;sterol metabolic process;0.00680183142129034!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00694900760519357!GO:0006509;membrane protein ectodomain proteolysis;0.00725155886603473!GO:0033619;membrane protein proteolysis;0.00725155886603473!GO:0005774;vacuolar membrane;0.00731237213332878!GO:0006402;mRNA catabolic process;0.0073210932642561!GO:0042158;lipoprotein biosynthetic process;0.0073210932642561!GO:0043154;negative regulation of caspase activity;0.00735068199511854!GO:0030125;clathrin vesicle coat;0.00735068199511854!GO:0030665;clathrin coated vesicle membrane;0.00735068199511854!GO:0046982;protein heterodimerization activity;0.00740046801927911!GO:0006400;tRNA modification;0.00741322793360758!GO:0004549;tRNA-specific ribonuclease activity;0.00755436255760955!GO:0008629;induction of apoptosis by intracellular signals;0.00787719279860629!GO:0044255;cellular lipid metabolic process;0.00787719279860629!GO:0004526;ribonuclease P activity;0.00796659743295551!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.00800788452315779!GO:0006778;porphyrin metabolic process;0.00808647229019243!GO:0033013;tetrapyrrole metabolic process;0.00808647229019243!GO:0006807;nitrogen compound metabolic process;0.0081438256088174!GO:0009124;nucleoside monophosphate biosynthetic process;0.00817157548091978!GO:0009123;nucleoside monophosphate metabolic process;0.00817157548091978!GO:0031970;organelle envelope lumen;0.00824900118820394!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00826263918306168!GO:0043022;ribosome binding;0.0083634799766504!GO:0046966;thyroid hormone receptor binding;0.00844464302336772!GO:0004003;ATP-dependent DNA helicase activity;0.00845612217181874!GO:0051539;4 iron, 4 sulfur cluster binding;0.00846215130081045!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.00861270399348106!GO:0008250;oligosaccharyl transferase complex;0.00861270399348106!GO:0045792;negative regulation of cell size;0.00893031009030153!GO:0005832;chaperonin-containing T-complex;0.00909179108355912!GO:0030660;Golgi-associated vesicle membrane;0.00926337678777384!GO:0006891;intra-Golgi vesicle-mediated transport;0.00991932658481202!GO:0031326;regulation of cellular biosynthetic process;0.00993415163584!GO:0031570;DNA integrity checkpoint;0.00999743039733969!GO:0016616;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;0.0102653095941759!GO:0004576;oligosaccharyl transferase activity;0.0102653095941759!GO:0030308;negative regulation of cell growth;0.0105171964725414!GO:0008139;nuclear localization sequence binding;0.0105269752267109!GO:0030659;cytoplasmic vesicle membrane;0.0105269752267109!GO:0016407;acetyltransferase activity;0.0106082984641144!GO:0032259;methylation;0.0108081206664607!GO:0009119;ribonucleoside metabolic process;0.0109816400042093!GO:0043414;biopolymer methylation;0.0109832816305736!GO:0007034;vacuolar transport;0.0109899487764268!GO:0007010;cytoskeleton organization and biogenesis;0.0110031478631648!GO:0031124;mRNA 3'-end processing;0.0117622873034393!GO:0006979;response to oxidative stress;0.0117688221118187!GO:0000725;recombinational repair;0.0118156607442605!GO:0000724;double-strand break repair via homologous recombination;0.0118156607442605!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0120308689471054!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0120704440693519!GO:0006289;nucleotide-excision repair;0.0121743221123085!GO:0044438;microbody part;0.0122724944912083!GO:0044439;peroxisomal part;0.0122724944912083!GO:0030521;androgen receptor signaling pathway;0.0126821455287127!GO:0009889;regulation of biosynthetic process;0.0127005981868319!GO:0007050;cell cycle arrest;0.0127005981868319!GO:0005744;mitochondrial inner membrane presequence translocase complex;0.0127310998394009!GO:0000339;RNA cap binding;0.0128045257769627!GO:0000922;spindle pole;0.0128535859817641!GO:0030119;AP-type membrane coat adaptor complex;0.0128693669819989!GO:0005869;dynactin complex;0.0129046960048419!GO:0051338;regulation of transferase activity;0.0130655951134791!GO:0006066;alcohol metabolic process;0.013079402362218!GO:0012506;vesicle membrane;0.01325234029816!GO:0007021;tubulin folding;0.0136643211082458!GO:0016614;oxidoreductase activity, acting on CH-OH group of donors;0.0138341614522906!GO:0004540;ribonuclease activity;0.0141094413878257!GO:0000175;3'-5'-exoribonuclease activity;0.0141160775876324!GO:0006740;NADPH regeneration;0.0143013402056104!GO:0006098;pentose-phosphate shunt;0.0143013402056104!GO:0005862;muscle thin filament tropomyosin;0.0145095663674379!GO:0006096;glycolysis;0.0147755141004064!GO:0043488;regulation of mRNA stability;0.0147755141004064!GO:0043487;regulation of RNA stability;0.0147755141004064!GO:0006338;chromatin remodeling;0.0148665062739203!GO:0000070;mitotic sister chromatid segregation;0.0150370165430365!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0151270361911224!GO:0045039;protein import into mitochondrial inner membrane;0.0151270361911224!GO:0016788;hydrolase activity, acting on ester bonds;0.0151670752900622!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.015200317185709!GO:0004523;ribonuclease H activity;0.0152428723361052!GO:0043433;negative regulation of transcription factor activity;0.0162115558275289!GO:0043624;cellular protein complex disassembly;0.0162224714369467!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0164846199374464!GO:0030131;clathrin adaptor complex;0.0165813096429464!GO:0009308;amine metabolic process;0.0167164548889871!GO:0006779;porphyrin biosynthetic process;0.0167164548889871!GO:0033014;tetrapyrrole biosynthetic process;0.0167164548889871!GO:0044437;vacuolar part;0.0167164548889871!GO:0009303;rRNA transcription;0.0168561416957332!GO:0005874;microtubule;0.016932164790505!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0169741518421403!GO:0005669;transcription factor TFIID complex;0.0169741518421403!GO:0043549;regulation of kinase activity;0.0171495760109918!GO:0008234;cysteine-type peptidase activity;0.01716496994949!GO:0046983;protein dimerization activity;0.0174280864539148!GO:0044433;cytoplasmic vesicle part;0.0174443316064936!GO:0030133;transport vesicle;0.0174530940102462!GO:0000030;mannosyltransferase activity;0.017694920637091!GO:0003702;RNA polymerase II transcription factor activity;0.017694920637091!GO:0005663;DNA replication factor C complex;0.017694920637091!GO:0031903;microbody membrane;0.0182368576974477!GO:0005778;peroxisomal membrane;0.0182368576974477!GO:0006769;nicotinamide metabolic process;0.018249386751276!GO:0009161;ribonucleoside monophosphate metabolic process;0.018249386751276!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.018249386751276!GO:0050178;phenylpyruvate tautomerase activity;0.0186477135627051!GO:0004659;prenyltransferase activity;0.0187196712730243!GO:0000819;sister chromatid segregation;0.0188881702248459!GO:0044454;nuclear chromosome part;0.0188886745311976!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0188886745311976!GO:0010257;NADH dehydrogenase complex assembly;0.0188886745311976!GO:0033108;mitochondrial respiratory chain complex assembly;0.0188886745311976!GO:0050681;androgen receptor binding;0.0188886745311976!GO:0008538;proteasome activator activity;0.0209287513676458!GO:0005765;lysosomal membrane;0.0209755905052971!GO:0006378;mRNA polyadenylation;0.0209995116488157!GO:0009003;signal peptidase activity;0.0209995116488157!GO:0032984;macromolecular complex disassembly;0.0210323169786162!GO:0048144;fibroblast proliferation;0.0210323169786162!GO:0048145;regulation of fibroblast proliferation;0.0210323169786162!GO:0008652;amino acid biosynthetic process;0.0212225981072141!GO:0048146;positive regulation of fibroblast proliferation;0.0212691093356409!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0214922315553238!GO:0030508;thiol-disulfide exchange intermediate activity;0.0217593136677476!GO:0042168;heme metabolic process;0.02178110379162!GO:0050794;regulation of cellular process;0.021816791606871!GO:0046519;sphingoid metabolic process;0.021951714397994!GO:0005853;eukaryotic translation elongation factor 1 complex;0.0221644075418637!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.0224811838177244!GO:0000726;non-recombinational repair;0.0232025831141084!GO:0006730;one-carbon compound metabolic process;0.0232025831141084!GO:0018196;peptidyl-asparagine modification;0.0232025831141084!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0232025831141084!GO:0006643;membrane lipid metabolic process;0.0232228858479079!GO:0003923;GPI-anchor transamidase activity;0.0237718595518838!GO:0016255;attachment of GPI anchor to protein;0.0237718595518838!GO:0042765;GPI-anchor transamidase complex;0.0237718595518838!GO:0006354;RNA elongation;0.0237950861407556!GO:0001836;release of cytochrome c from mitochondria;0.0239606507990439!GO:0009967;positive regulation of signal transduction;0.0240842259436704!GO:0007040;lysosome organization and biogenesis;0.0245739360018833!GO:0005996;monosaccharide metabolic process;0.0246323262213185!GO:0006360;transcription from RNA polymerase I promoter;0.0250175747484242!GO:0008092;cytoskeletal protein binding;0.0251022139272627!GO:0045859;regulation of protein kinase activity;0.0259094429202658!GO:0006213;pyrimidine nucleoside metabolic process;0.0262448943115028!GO:0019318;hexose metabolic process;0.0263825976476063!GO:0051059;NF-kappaB binding;0.0264712652496004!GO:0031406;carboxylic acid binding;0.0265177543559656!GO:0006672;ceramide metabolic process;0.0266651171493259!GO:0022406;membrane docking;0.0268469288304028!GO:0048278;vesicle docking;0.0268469288304028!GO:0051053;negative regulation of DNA metabolic process;0.0271751287384251!GO:0031529;ruffle organization and biogenesis;0.0275662043575508!GO:0006541;glutamine metabolic process;0.0280349179253254!GO:0004860;protein kinase inhibitor activity;0.0280368419663439!GO:0043189;H4/H2A histone acetyltransferase complex;0.0280483742191086!GO:0006006;glucose metabolic process;0.0280483742191086!GO:0042364;water-soluble vitamin biosynthetic process;0.0282649723838497!GO:0006749;glutathione metabolic process;0.0284313059779422!GO:0046822;regulation of nucleocytoplasmic transport;0.0284625412199423!GO:0008017;microtubule binding;0.0288608510269545!GO:0043241;protein complex disassembly;0.0293531949081863!GO:0005732;small nucleolar ribonucleoprotein complex;0.0293834515307729!GO:0006376;mRNA splice site selection;0.029521146531016!GO:0000389;nuclear mRNA 3'-splice site recognition;0.029521146531016!GO:0016197;endosome transport;0.0295454054128842!GO:0004448;isocitrate dehydrogenase activity;0.0300196376357277!GO:0030134;ER to Golgi transport vesicle;0.0300196376357277!GO:0019362;pyridine nucleotide metabolic process;0.0304682063429635!GO:0016791;phosphoric monoester hydrolase activity;0.0304730468433926!GO:0048518;positive regulation of biological process;0.0308710149304895!GO:0006644;phospholipid metabolic process;0.031310769632481!GO:0017166;vinculin binding;0.0313930331586679!GO:0005658;alpha DNA polymerase:primase complex;0.0315269406951185!GO:0006220;pyrimidine nucleotide metabolic process;0.0317833518195815!GO:0016790;thiolester hydrolase activity;0.0319414756212609!GO:0003857;3-hydroxyacyl-CoA dehydrogenase activity;0.0320917765826153!GO:0015036;disulfide oxidoreductase activity;0.0321278073687259!GO:0004861;cyclin-dependent protein kinase inhibitor activity;0.0325200598044252!GO:0007017;microtubule-based process;0.0328160276459167!GO:0046365;monosaccharide catabolic process;0.0328313698860954!GO:0046128;purine ribonucleoside metabolic process;0.0331388920622453!GO:0042278;purine nucleoside metabolic process;0.0331388920622453!GO:0042769;DNA damage response, detection of DNA damage;0.0331871023300796!GO:0005777;peroxisome;0.0332752137444226!GO:0042579;microbody;0.0332752137444226!GO:0008299;isoprenoid biosynthetic process;0.0332823224704993!GO:0007041;lysosomal transport;0.0339641822718904!GO:0000792;heterochromatin;0.0342504249040994!GO:0000152;nuclear ubiquitin ligase complex;0.0344871179557922!GO:0006629;lipid metabolic process;0.0349575982871909!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0350683055276171!GO:0008203;cholesterol metabolic process;0.0351811754691802!GO:0008536;Ran GTPase binding;0.0352127911825127!GO:0019783;small conjugating protein-specific protease activity;0.0352993127070202!GO:0030677;ribonuclease P complex;0.0353321689279068!GO:0050811;GABA receptor binding;0.0355644335954301!GO:0030127;COPII vesicle coat;0.0357134144547071!GO:0012507;ER to Golgi transport vesicle membrane;0.0357134144547071!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0357134144547071!GO:0009081;branched chain family amino acid metabolic process;0.0362049474986679!GO:0006739;NADP metabolic process;0.0362053594586975!GO:0031371;ubiquitin conjugating enzyme complex;0.0362962884351461!GO:0005784;translocon complex;0.0365290834541163!GO:0031123;RNA 3'-end processing;0.0365290834541163!GO:0006904;vesicle docking during exocytosis;0.0366217237964675!GO:0051716;cellular response to stimulus;0.0367177461621364!GO:0019206;nucleoside kinase activity;0.0369683726142528!GO:0030032;lamellipodium biogenesis;0.037134822345895!GO:0007033;vacuole organization and biogenesis;0.0372852267001913!GO:0045926;negative regulation of growth;0.0375451645654476!GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;0.0375451645654476!GO:0006596;polyamine biosynthetic process;0.0378169302376247!GO:0035267;NuA4 histone acetyltransferase complex;0.0380155880124181!GO:0045893;positive regulation of transcription, DNA-dependent;0.0383254831409102!GO:0000077;DNA damage checkpoint;0.0383254831409102!GO:0045936;negative regulation of phosphate metabolic process;0.0389478873345234!GO:0006917;induction of apoptosis;0.0394820636179529!GO:0030911;TPR domain binding;0.039733632772943!GO:0031227;intrinsic to endoplasmic reticulum membrane;0.0405928902596528!GO:0004843;ubiquitin-specific protease activity;0.0408062225638738!GO:0022411;cellular component disassembly;0.0413621799419519!GO:0003985;acetyl-CoA C-acetyltransferase activity;0.0413860085185469!GO:0046112;nucleobase biosynthetic process;0.0417318183450492!GO:0031577;spindle checkpoint;0.0422492323916077!GO:0016453;C-acetyltransferase activity;0.042364619683824!GO:0007346;regulation of progression through mitotic cell cycle;0.0425150281430794!GO:0030433;ER-associated protein catabolic process;0.0425150281430794!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0425150281430794!GO:0004748;ribonucleoside-diphosphate reductase activity;0.0438649350435231!GO:0016728;oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor;0.0438649350435231!GO:0030100;regulation of endocytosis;0.0443551349519524!GO:0008415;acyltransferase activity;0.0445999341717418!GO:0006783;heme biosynthetic process;0.0446023333133287!GO:0045892;negative regulation of transcription, DNA-dependent;0.044637856221639!GO:0046164;alcohol catabolic process;0.0447262703863249!GO:0001726;ruffle;0.0450506872492892!GO:0030503;regulation of cell redox homeostasis;0.0450668310496258!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0453499695313547!GO:0012502;induction of programmed cell death;0.0454457155096877!GO:0006897;endocytosis;0.0465720438214154!GO:0010324;membrane invagination;0.0465720438214154!GO:0016417;S-acyltransferase activity;0.0468666717266247!GO:0030036;actin cytoskeleton organization and biogenesis;0.0469513719363985!GO:0008426;protein kinase C inhibitor activity;0.0473755368308654!GO:0003988;acetyl-CoA C-acyltransferase activity;0.0476683588820414!GO:0005971;ribonucleoside-diphosphate reductase complex;0.0477972501278958!GO:0030518;steroid hormone receptor signaling pathway;0.0484494569907502!GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors;0.0484797877085477!GO:0001522;pseudouridine synthesis;0.0485371124368722!GO:0016860;intramolecular oxidoreductase activity;0.0487971608754885!GO:0008287;protein serine/threonine phosphatase complex;0.0491824615806516!GO:0005754;mitochondrial proton-transporting ATP synthase, catalytic core;0.0491824615806516!GO:0000275;mitochondrial proton-transporting ATP synthase complex, catalytic core F(1);0.0491824615806516!GO:0045267;proton-transporting ATP synthase, catalytic core;0.0491824615806516!GO:0008601;protein phosphatase type 2A regulator activity;0.0493685172647824!GO:0048468;cell development;0.0496445866699911 | |||
|sample_id=11894 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue= | |||
|top_motifs=ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.96146599585;HES1:1.84384225587;FOXQ1:1.66176322348;E2F1..5:1.55200980964;ESRRA:1.53499155208;NR5A1,2:1.47317969871;FOXM1:1.33248571484;PPARG:1.28903526227;ELK1,4_GABP{A,B1}:1.14985498036;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.12141516455;YY1:0.966405704251;bHLH_family:0.90525608562;HIF1A:0.793611477784;NR6A1:0.731328064981;ZNF143:0.723984212349;NRF1:0.694462422964;NKX3-1:0.687817888892;HOX{A6,A7,B6,B7}:0.671680050668;PAX1,9:0.608212437306;NFY{A,B,C}:0.607625683924;ARID5B:0.605722042048;MYB:0.603798841982;HNF4A_NR2F1,2:0.603641451959;FOXD3:0.572239791365;EP300:0.570254141163;NKX3-2:0.566087567053;NFE2L1:0.517319889938;ZEB1:0.503380773948;FOXN1:0.501251400928;IKZF1:0.486099672952;SNAI1..3:0.480565199065;PAX8:0.442555167171;PAX5:0.419781480783;TEAD1:0.413124261386;TBX4,5:0.394545179742;ZBTB16:0.379855476449;IKZF2:0.348487852382;IRF7:0.334383380947;UFEwm:0.330735540867;GCM1,2:0.310746586525;CREB1:0.303561164357;MYOD1:0.288542164763;GFI1:0.287366834182;HOXA9_MEIS1:0.283194995053;POU3F1..4:0.27722421711;TP53:0.271931984563;POU1F1:0.254818363261;ZNF148:0.231439204032;PAX2:0.229016203645;GTF2A1,2:0.168445938065;FOX{F1,F2,J1}:0.161411556105;ALX4:0.141166932364;HOX{A5,B5}:0.135624093949;ATF5_CREB3:0.129572368824;RXR{A,B,G}:0.129156400885;HLF:0.117531451332;VSX1,2:0.102023649756;MYBL2:0.0878024435129;OCT4_SOX2{dimer}:0.082264312568;BACH2:0.0732428150258;HAND1,2:0.0652451279799;NFE2:0.0566242632324;NFE2L2:0.0515076757951;CDC5L:0.046026053031;RFX2..5_RFXANK_RFXAP:0.043710975854;LHX3,4:0.043459084862;TFDP1:0.0238898604659;PITX1..3:0.0144212979736;HSF1,2:0.000151200844005;TEF:-0.0125635194609;RORA:-0.0147838680369;GFI1B:-0.0166888647734;EN1,2:-0.022678903936;FOS_FOS{B,L1}_JUN{B,D}:-0.0353905763576;GLI1..3:-0.0429768651324;TBP:-0.0472501338611;HNF1A:-0.0515870385566;CDX1,2,4:-0.0559988469277;ZNF423:-0.0720903139421;LEF1_TCF7_TCF7L1,2:-0.0738189120308;ZNF384:-0.08064408537;MEF2{A,B,C,D}:-0.0816029923765;MTF1:-0.0937159680725;ONECUT1,2:-0.0946682462415;CUX2:-0.102133402107;ATF6:-0.103820695261;FOXP3:-0.105594818453;ESR1:-0.11252573196;SOX{8,9,10}:-0.113077041903;PRRX1,2:-0.122054486967;PAX4:-0.1701605415;NR1H4:-0.173833645188;ELF1,2,4:-0.175235391623;ZBTB6:-0.180563314551;SREBF1,2:-0.189970770244;HOX{A4,D4}:-0.19267373803;ALX1:-0.196152007748;STAT2,4,6:-0.196764024916;LMO2:-0.202857028532;NR3C1:-0.203928290053;NANOG:-0.206636546773;PDX1:-0.216783533633;PAX3,7:-0.221433109988;NFKB1_REL_RELA:-0.234176629356;BREu{core}:-0.241592240157;NKX2-2,8:-0.242129465505;CEBPA,B_DDIT3:-0.251954391005;GZF1:-0.252029271381;FOXL1:-0.252485312778;NKX6-1,2:-0.263143030021;TLX1..3_NFIC{dimer}:-0.268584696106;ATF4:-0.282537035876;FOSL2:-0.305401793647;PBX1:-0.311066535075;STAT5{A,B}:-0.31891577695;AHR_ARNT_ARNT2:-0.323460805926;MAFB:-0.332962477559;AIRE:-0.340016456215;JUN:-0.351017291324;IRF1,2:-0.366689393621;EBF1:-0.38429523301;KLF4:-0.386394764688;NKX2-1,4:-0.426565931132;RBPJ:-0.427912498759;HBP1_HMGB_SSRP1_UBTF:-0.434032933059;PAX6:-0.436829339293;HIC1:-0.443988275727;DBP:-0.44806147477;NFIL3:-0.457597120791;SPIB:-0.457616931664;TFCP2:-0.485137409159;HMGA1,2:-0.49035219223;FOX{I1,J2}:-0.49374604123;ADNP_IRX_SIX_ZHX:-0.495389824302;GTF2I:-0.49780035724;RFX1:-0.498099188569;GATA6:-0.522199475337;BPTF:-0.523671672949;ZFP161:-0.535013572383;FOXP1:-0.539884784904;POU2F1..3:-0.542534988271;EVI1:-0.551248337649;T:-0.557882473877;SRF:-0.558543733757;CRX:-0.564656077691;SPI1:-0.617237395864;RXRA_VDR{dimer}:-0.648424230498;TFAP2B:-0.671565266861;SP1:-0.68487934896;SOX5:-0.694825350379;TFAP2{A,C}:-0.698445384393;AR:-0.700779746523;RUNX1..3:-0.704022237358;SOX17:-0.704244634538;FOXA2:-0.711704665724;TOPORS:-0.722917982193;NFATC1..3:-0.746021275997;TFAP4:-0.760813703872;ETS1,2:-0.768828172319;MED-1{core}:-0.76937811795;EGR1..3:-0.820048342089;NKX2-3_NKX2-5:-0.822164366439;XCPE1{core}:-0.82301509056;GATA4:-0.834813646418;REST:-0.851408937131;FOX{D1,D2}:-0.853476936002;DMAP1_NCOR{1,2}_SMARC:-0.888532277693;NHLH1,2:-0.892075983351;ZNF238:-0.92512313282;TAL1_TCF{3,4,12}:-0.930767038934;ATF2:-0.949615790923;POU6F1:-0.949922169675;SOX2:-0.95261668456;ZIC1..3:-0.964360236676;FOXO1,3,4:-0.973024181432;XBP1:-0.989318111656;POU5F1:-1.01350395746;MAZ:-1.03403136927;RREB1:-1.06610930211;MYFfamily:-1.10068880745;MTE{core}:-1.13926383654;PRDM1:-1.19161956402;MZF1:-1.26449697154;NFIX:-1.27399556276;PATZ1:-1.29202580971;SMAD1..7,9:-1.30411342839;TGIF1:-1.317275746;STAT1,3:-1.33149751431;TLX2:-1.39654741363;NANOG{mouse}:-1.48372951898;HMX1:-1.49442868737;SPZ1:-1.92865538494 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11894-125E4;search_select_hide=table117:FF:11894-125E4 | |||
}} | }} |
Latest revision as of 18:27, 4 June 2020
Name: | Hep-2 cells treated with Streptococci strain JRS4, biol_rep1 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13478 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13478
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13478
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0599 |
10 | 10 | 0.0498 |
100 | 100 | 0.0156 |
101 | 101 | 0.155 |
102 | 102 | 0.74 |
103 | 103 | 0.795 |
104 | 104 | 0.923 |
105 | 105 | 0.36 |
106 | 106 | 0.126 |
107 | 107 | 0.23 |
108 | 108 | 0.728 |
109 | 109 | 6.53345e-4 |
11 | 11 | 0.588 |
110 | 110 | 0.189 |
111 | 111 | 0.765 |
112 | 112 | 0.659 |
113 | 113 | 0.00327 |
114 | 114 | 0.416 |
115 | 115 | 0.804 |
116 | 116 | 0.138 |
117 | 117 | 0.0803 |
118 | 118 | 0.0654 |
119 | 119 | 0.307 |
12 | 12 | 0.832 |
120 | 120 | 0.0608 |
121 | 121 | 0.397 |
122 | 122 | 0.187 |
123 | 123 | 0.287 |
124 | 124 | 0.605 |
125 | 125 | 0.727 |
126 | 126 | 0.53 |
127 | 127 | 0.2 |
128 | 128 | 0.00125 |
129 | 129 | 0.548 |
13 | 13 | 5.28612e-5 |
130 | 130 | 0.821 |
131 | 131 | 0.433 |
132 | 132 | 0.605 |
133 | 133 | 0.233 |
134 | 134 | 0.902 |
135 | 135 | 0.0423 |
136 | 136 | 0.00834 |
137 | 137 | 0.317 |
138 | 138 | 0.512 |
139 | 139 | 0.144 |
14 | 14 | 0.654 |
140 | 140 | 0.506 |
141 | 141 | 0.279 |
142 | 142 | 0.853 |
143 | 143 | 0.346 |
144 | 144 | 0.39 |
145 | 145 | 0.369 |
146 | 146 | 0.742 |
147 | 147 | 0.567 |
148 | 148 | 0.331 |
149 | 149 | 0.4 |
15 | 15 | 0.584 |
150 | 150 | 0.683 |
151 | 151 | 0.665 |
152 | 152 | 0.993 |
153 | 153 | 0.704 |
154 | 154 | 0.411 |
155 | 155 | 0.351 |
156 | 156 | 0.0874 |
157 | 157 | 0.119 |
158 | 158 | 0.19 |
159 | 159 | 0.216 |
16 | 16 | 0.484 |
160 | 160 | 0.255 |
161 | 161 | 0.568 |
162 | 162 | 0.623 |
163 | 163 | 0.295 |
164 | 164 | 0.0122 |
165 | 165 | 0.619 |
166 | 166 | 0.0667 |
167 | 167 | 0.208 |
168 | 168 | 0.434 |
169 | 169 | 0.108 |
17 | 17 | 0.707 |
18 | 18 | 0.267 |
19 | 19 | 0.933 |
2 | 2 | 0.522 |
20 | 20 | 0.0562 |
21 | 21 | 0.123 |
22 | 22 | 0.855 |
23 | 23 | 0.00942 |
24 | 24 | 0.513 |
25 | 25 | 0.273 |
26 | 26 | 0.592 |
27 | 27 | 0.687 |
28 | 28 | 0.888 |
29 | 29 | 0.00484 |
3 | 3 | 0.965 |
30 | 30 | 0.291 |
31 | 31 | 0.639 |
32 | 32 | 0.31 |
33 | 33 | 0.132 |
34 | 34 | 0.235 |
35 | 35 | 0.954 |
36 | 36 | 0.0533 |
37 | 37 | 0.168 |
38 | 38 | 0.772 |
39 | 39 | 0.919 |
4 | 4 | 0.235 |
40 | 40 | 0.00381 |
41 | 41 | 0.161 |
42 | 42 | 0.802 |
43 | 43 | 0.688 |
44 | 44 | 0.0348 |
45 | 45 | 0.241 |
46 | 46 | 0.985 |
47 | 47 | 0.262 |
48 | 48 | 0.292 |
49 | 49 | 0.348 |
5 | 5 | 0.304 |
50 | 50 | 0.829 |
51 | 51 | 0.741 |
52 | 52 | 0.378 |
53 | 53 | 0.161 |
54 | 54 | 0.701 |
55 | 55 | 0.0387 |
56 | 56 | 0.907 |
57 | 57 | 0.431 |
58 | 58 | 0.99 |
59 | 59 | 0.788 |
6 | 6 | 0.581 |
60 | 60 | 0.671 |
61 | 61 | 0.0303 |
62 | 62 | 0.623 |
63 | 63 | 0.417 |
64 | 64 | 0.504 |
65 | 65 | 0.606 |
66 | 66 | 0.783 |
67 | 67 | 0.548 |
68 | 68 | 0.541 |
69 | 69 | 0.903 |
7 | 7 | 0.0174 |
70 | 70 | 0.642 |
71 | 71 | 0.0147 |
72 | 72 | 0.995 |
73 | 73 | 0.232 |
74 | 74 | 0.134 |
75 | 75 | 0.0615 |
76 | 76 | 0.126 |
77 | 77 | 0.361 |
78 | 78 | 0.0983 |
79 | 79 | 0.903 |
8 | 8 | 0.0566 |
80 | 80 | 0.0608 |
81 | 81 | 0.259 |
82 | 82 | 0.366 |
83 | 83 | 0.38 |
84 | 84 | 0.718 |
85 | 85 | 0.0314 |
86 | 86 | 0.977 |
87 | 87 | 0.0025 |
88 | 88 | 0.826 |
89 | 89 | 0.744 |
9 | 9 | 0.586 |
90 | 90 | 0.0349 |
91 | 91 | 0.0134 |
92 | 92 | 0.3 |
93 | 93 | 0.353 |
94 | 94 | 0.548 |
95 | 95 | 0.00316 |
96 | 96 | 0.535 |
97 | 97 | 0.785 |
98 | 98 | 0.733 |
99 | 99 | 0.398 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13478
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0011134 human Hep-2 cells treated with Streptococci strain JRS4 sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000066 (epithelial cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
162 (cancer)
14566 (disease of cellular proliferation)
0050687 (cell type cancer)
305 (carcinoma)
UBERON: Anatomy
0000468 (multi-cellular organism)
0001737 (larynx)
0000064 (organ part)
0004119 (endoderm-derived structure)
0000062 (organ)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000063 (organ segment)
0000477 (anatomical cluster)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0000072 (segment of respiratory tract)
0010317 (germ layer / neural crest derived structure)
0000065 (respiratory tract)
0001004 (respiratory system)
0001557 (upper respiratory tract)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0000625 (experimental infection sample)
0000350 (experimentally modified sample)
0000632 (group A streptococci treatment sample)
0104978 (HEp-2 cell sample)
0000639 (Streptococcus strain JRS4 treatment sample)
0100297 (carcinoma cell line sample)
0101120 (epithelial cell line sample)
0011134 (human Hep-2 cells treated with Streptococci strain JRS4 sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
UBERON:0008947 (respiratory primordium)
UBERON:0002532 (epiblast (generic))
UBERON:0006595 (presumptive endoderm)
UBERON:0010316 (germ layer / neural crest)