FF:11896-125E6: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005842 | ||
| | |accession_numbers=CAGE;DRX007790;DRR008662;DRZ000087;DRZ001472;DRZ011437;DRZ012822 | ||
| | |ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0001737,UBERON:0000064,UBERON:0004119,UBERON:0000062,UBERON:0000061,UBERON:0000465,UBERON:0000063,UBERON:0000477,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0000072,UBERON:0010317,UBERON:0000065,UBERON:0001004,UBERON:0001557 | ||
| | |ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0000066,CL:0000255 | ||
| | |ancestors_in_disease_facet=DOID:4,DOID:162,DOID:14566,DOID:0050687,DOID:305 | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0000625,FF:0000350,FF:0000632,FF:0104978,FF:0000639,FF:0100297,FF:0101120,FF:0011134 | ||
| | |comment= | ||
| | |created_by= | ||
| | |creation_date= | ||
| | |data_phase=2 | ||
| | |datafreeze_phase=2 | ||
| | |def= | ||
| | |expression_enrichment_score=chr6:10415276..10415341,-!p2@TFAP2A!1.56!43.09!TFAP2A;;chr1:201979743..201979762,+!p1@ELF3!1.52!32.32!ELF3;;chr2:238592039..238592054,+!p4@LRRFIP1!1.51!31.55!LRRFIP1;;chr6:10415484..10415508,-!p3@TFAP2A!1.44!26.55!TFAP2A;;chr5:134369905..134369972,-!p1@PITX1!1.39!35.78!PITX1;;chr6:126240380..126240430,+!p2@NCOA7!1.37!56.56!NCOA7;;chr12:52445218..52445237,+!p1@NR4A1!1.35!262.78!NR4A1;;chr6:10412600..10412637,-!p1@TFAP2A!1.35!35.01!TFAP2A;;chr5:134369879..134369898,-!p2@PITX1!1.31!19.24!PITX1;;chr6:126240442..126240459,+!p4@NCOA7!1.28!22.70!NCOA7;;chr1:201979703..201979721,+!p2@ELF3!1.20!15.01!ELF3;;chr6:1312325..1312340,+!p1@FOXQ1!1.19!23.85!FOXQ1;;chr6:126240463..126240489,+!p6@NCOA7!1.18!15.77!NCOA7;;chr12:54380036..54380091,+!p4@HOXC10!1.07!10.77!HOXC10;;chr12:54380404..54380433,+!p3@HOXC10!1.06!10.39!HOXC10;;chr22:19748231..19748317,+!p1@TBX1!1.06!10.39!TBX1;;chr5:170736243..170736279,+!p1@TLX3!1.06!10.39!TLX3;;chr17:46687959..46688007,-!p2@HOXB7!1.05!14.24!HOXB7;;chr9:100615499..100615519,+!p1@FOXE1!1.03!9.62!FOXE1;;chr1:44513995..44514031,+!p1@KLF17!1.03!9.62!KLF17;;chr18:55102598..55102623,+!p1@ONECUT2!1.01!9.23!ONECUT2;;chr18:55102628..55102646,+!p2@ONECUT2!0.98!8.46!ONECUT2;;chrX:131624056..131624069,-!p2@MBNL3!0.96!11.16!MBNL3;;chr6:126240356..126240379,+!p7@NCOA7!0.96!10.00!NCOA7;;chr7:101917447..101917479,+!p4@CUX1!0.96!8.08!CUX1;;chr7:101917482..101917507,+!p6@CUX1!0.94!7.69!CUX1;;chr12:72056800..72056834,+!p1@THAP2!0.92!10.00!THAP2;;chr17:7492684..7492778,-!p2@SOX15!0.91!15.39!SOX15;;chr10:104155659..104155676,+!p4@NFKB2!0.90!8.85!NFKB2;;chr6:10412392..10412409,-!p4@TFAP2A!0.90!8.08!TFAP2A;;chr13:73633131..73633149,+!p1@KLF5!0.88!73.87!KLF5;;chr6:10412576..10412599,-!p5@TFAP2A!0.88!6.54!TFAP2A;;chr17:17726907..17726958,-!p2@SREBF1!0.87!41.94!SREBF1;;chr3:69915385..69915438,+!p3@MITF!0.85!6.16!MITF;;chr9:102584262..102584276,+!p1@NR4A3!0.83!13.47!NR4A3;;chr6:1389789..1389821,+!p1@FOXF2!0.83!8.08!FOXF2;;chr11:34663913..34663945,+!p6@EHF!0.83!5.77!EHF;;chr5:321810..321877,+!p1@AHRR!0.82!18.85!AHRR;;chr20:6748325..6748352,+!p1@BMP2!0.81!8.08!BMP2;;chr21:38071430..38071456,+!p1@SIM2!0.81!5.39!SIM2;;chr7:101917407..101917443,+!p3@CUX1!0.81!5.39!CUX1;;chr7:27224842..27224872,-!p1@HOXA11!0.81!5.39!HOXA11;;chr12:54379029..54379057,+!p2@HOXC10!0.81!5.39!HOXC10;;chrX:70503529..70503549,+!p2@NONO!0.80!30.78!NONO;;chr1:8934931..8934947,-!p4@ENO1!0.80!18.85!ENO1;;chr12:72056773..72056796,+!p3@THAP2!0.79!6.93!THAP2;;chr9:102584159..102584174,+!p2@NR4A3!0.78!9.62!NR4A3;;chr8:55370487..55370503,+!p1@SOX17!0.78!5.00!SOX17;;chr10:28034739..28034756,-!p1@MKX!0.78!5.00!MKX;;chr12:54378923..54378966,+!p1@HOXC10!0.78!5.00!HOXC10;;chr1:151804244..151804310,-!p1@RORC!0.78!5.00!RORC;;chr17:46682321..46682362,-!p1@HOXB6!0.78!5.00!HOXB6;;chrX:131623044..131623089,-!p1@MBNL3!0.77!22.32!MBNL3;;chr16:29818199..29818216,+!p11@MAZ!0.77!8.46!MAZ;;chr1:45805872..45805900,+!p2@TOE1!0.76!12.31!TOE1;;chr1:8938709..8938720,-!p3@ENO1!0.75!247.39!ENO1;;chr20:42295745..42295765,+!p1@MYBL2!0.75!84.64!MYBL2;;chr17:8027418..8027432,-!p1@HES7!0.75!4.62!HES7;;chr12:3068544..3068597,+!p1@TEAD4!0.74!30.01!TEAD4;;chr6:31126291..31126399,+!p1@TCF19!0.73!46.17!TCF19;;chr12:7079780..7079791,-!p2@PHB2!0.72!24.62!PHB2;;chrX:107019163..107019179,-!p7@TSC22D3!0.72!5.00!TSC22D3;;chr12:54380112..54380126,+!p5@HOXC10!0.72!4.23!HOXC10;;chr2:157189180..157189290,-!p1@NR4A2!0.71!24.24!NR4A2;;chr1:935398..935465,-!p2@HES4!0.71!9.23!HES4;;chr20:42295713..42295738,+!p2@MYBL2!0.70!26.55!MYBL2;;chr10:51572408..51572454,+!p3@NCOA4!0.70!26.16!NCOA4;;chr3:12330560..12330579,+!p1@PPARG!0.69!4.62!PPARG;;chr2:45236540..45236577,-!p1@SIX2!0.69!3.85!SIX2;;chr3:128207349..128207386,-!p3@GATA2!0.69!3.85!GATA2;;chr3:69915369..69915381,+!p4@MITF!0.69!3.85!MITF;;chr9:126774018..126774055,+!p1@LHX2!0.69!3.85!LHX2;;chr17:26697276..26697303,-!p2@SEBOX,p2@VTN!0.69!3.85!SEBOX;;chr3:128206762..128206781,-!p2@GATA2!0.66!25.78!GATA2;;chr2:172967621..172967637,-!p1@DLX2!0.66!10.77!DLX2;;chr17:41277372..41277418,-!p1@BRCA1!0.65!14.24!BRCA1;;chr6:10420285..10420304,-!p18@TFAP2A!0.65!3.46!TFAP2A;;chr11:34664014..34664045,+!p4@EHF!0.65!3.46!EHF;;chr12:54379477..54379498,+!p5@HOXC5!0.65!3.46!HOXC5;;chr12:2986275..2986363,-!p1@FOXM1!0.64!39.24!FOXM1;;chr22:42229210..42229229,+!p3@SREBF2!0.64!8.85!SREBF2;;chr1:8939265..8939367,-!p5@ENO1!0.64!7.69!ENO1;;chr2:46524897..46524911,+!p2@EPAS1!0.63!10.39!EPAS1;;chr10:35484053..35484076,+!p1@CREM!0.62!8.85!CREM;;chrX:107018969..107019024,-!p6@TSC22D3!0.62!4.62!TSC22D3;;chrX:131622958..131622978,-!p3@MBNL3!0.62!4.23!MBNL3;;chr16:29818160..29818188,+!p6@MAZ!0.61!16.93!MAZ;;chr3:141087393..141087426,+!p3@ZBTB38!0.61!14.24!ZBTB38;;chr17:46687935..46687950,-!p3@HOXB7!0.61!3.08!HOXB7;;chr17:46806067..46806097,-!p1@HOXB13!0.61!3.08!HOXB13;;chr17:7493405..7493419,-!p1@SOX15!0.61!3.08!SOX15;;chrX:131623026..131623039,-!p5@MBNL3!0.61!3.08!MBNL3;;chr12:52448420..52448460,+!p5@NR4A1!0.61!3.08!NR4A1;;chr12:54332608..54332636,+!p1@HOXC13!0.61!3.08!HOXC13;;chr12:54379136..54379150,+!p4@HOXC5!0.61!3.08!HOXC5;;chr5:170736216..170736238,+!p2@TLX3!0.61!3.08!TLX3;;chr8:145669791..145669834,-!p1@TONSL!0.60!10.00!TONSL;;chr18:45457909..45457939,-!p8@SMAD2!0.60!3.85!SMAD2;;chr12:80084737..80084763,-!p3@PAWR!0.59!12.70!PAWR;;chr17:41623692..41623715,-!p1@ETV4!0.58!14.24!ETV4;;chr6:20402102..20402152,+!p1@E2F3!0.58!13.85!E2F3;;chr11:3400340..3400422,-!p1@ZNF195!0.57!53.48!ZNF195;;chr1:161736038..161736056,+!p4@ATF6!0.57!7.31!ATF6;;chr17:46688334..46688385,-!p1@HOXB7!0.57!4.23!HOXB7;;chr20:51588873..51588953,+!p1@TSHZ2!0.57!3.85!TSHZ2;;chrX:131624020..131624048,-!p9@MBNL3!0.57!3.46!MBNL3;;chr15:67418119..67418162,+!p5@SMAD3!0.57!3.08!SMAD3;;chr12:72056749..72056767,+!p6@THAP2!0.57!3.08!THAP2;;chr12:52448213..52448262,+!p6@NR4A1!0.57!2.69!NR4A1;;chr12:54393880..54393962,+!p1@HOXC9!0.57!2.69!HOXC9;;chr19:54041669..54041697,+!p2@ZNF331!0.57!2.69!ZNF331;;chr6:126240490..126240501,+!p11@NCOA7!0.57!2.69!NCOA7;;chr1:164528410..164528428,+!p1@PBX1!0.56!24.62!PBX1;;chr20:32274179..32274213,-!p1@E2F1!0.56!21.55!E2F1;;chrX:131623982..131624011,-!p6@MBNL3!0.56!4.23!MBNL3;;chr15:67418047..67418093,+!p4@SMAD3!0.55!3.46!SMAD3;;chr12:115121962..115121987,-!p1@TBX3!0.52!25.01!TBX3;;chr20:32274150..32274166,-!p2@E2F1!0.52!5.00!E2F1;;chr15:90294062..90294079,-!p2@MESP1!0.52!2.31!MESP1;;chr17:36105074..36105086,-!p2@HNF1B!0.52!2.31!HNF1B;;chr17:46806098..46806118,-!p3@HOXB13!0.52!2.31!HOXB13;;chr19:12348371..12348386,-!p5@ZNF44!0.52!2.31!ZNF44;;chr19:3574157..3574180,+!p4@HMG20B!0.52!2.31!HMG20B;;chr5:134369973..134369984,-!p3@PITX1!0.52!2.31!PITX1;;chr6:10412477..10412490,-!p10@TFAP2A!0.52!2.31!TFAP2A;;chr6:10419824..10419840,-!p9@TFAP2A!0.52!2.31!TFAP2A;;chr12:19592405..19592492,+!p2@AEBP2!0.51!25.01!AEBP2;;chr10:35415951..35415975,+!p8@CREM!0.51!3.46!CREM;;chr3:141087339..141087387,+!p2@ZBTB38!0.50!28.86!ZBTB38;;chr2:75937794..75937867,-!p2@GCFC2!0.50!5.77!GCFC2;;chr1:8938736..8938756,-!p1@ENO1!0.49!3076.05!ENO1;;chr11:47279504..47279563,+!p1@NR1H3!0.49!5.77!NR1H3;;chr8:67525443..67525459,-!p2@MYBL1!0.49!3.46!MYBL1;;chr6:43138999..43139017,+!p2@SRF!0.48!15.77!SRF;;chr17:47492252..47492265,-!p2@PHB!0.48!10.77!PHB;;chr18:47814010..47814021,-!p3@CXXC1!0.48!3.85!CXXC1;;chr2:85981222..85981259,+!p2@ATOH8!0.48!3.85!ATOH8;;chr1:8926441..8926473,-!p10@ENO1!0.48!3.46!ENO1;;chr1:23885981..23886002,-!p1@ID3!0.47!473.24!ID3;;chr5:34929677..34929789,+!p1@DNAJC21!0.47!78.10!DNAJC21;;chr1:23857698..23857733,-!p1@E2F2!0.47!4.23!E2F2;;chr2:239756739..239756755,+!p2@TWIST2!0.47!3.85!TWIST2;;chr17:17726892..17726903,-!p6@SREBF1!0.47!2.31!SREBF1;;chr17:48045917..48045977,+!p1@DLX4!0.47!1.92!DLX4;;chr17:48072574..48072597,-!p1@DLX3!0.47!1.92!DLX3;;chr2:63277948..63277974,+!p1@OTX1!0.47!1.92!OTX1;;chr3:138665937..138665968,-!p1@FOXL2!0.47!1.92!FOXL2;;chr10:104155680..104155687,+!p6@NFKB2!0.47!1.92!NFKB2;;chr12:3068634..3068656,+!p5@TEAD4!0.47!1.92!TEAD4;;chr12:51158359..51158395,+!p4@ATF1!0.47!1.92!ATF1;;chr12:54366975..54367001,+!p1@HOXC11!0.47!1.92!HOXC11;;chr12:54394416..54394467,+!p5@HOXC9!0.47!1.92!HOXC9;;chr14:37051798..37051831,-!p1@NKX2-8!0.47!1.92!NKX2-8;;chr5:134369643..134369675,-!p4@PITX1!0.47!1.92!PITX1;;chr6:10415263..10415274,-!p8@TFAP2A!0.47!1.92!TFAP2A;;chr6:126240542..126240553,+!p14@NCOA7!0.47!1.92!NCOA7;;chr6:1389989..1390019,+!p2@FOXF2!0.47!1.92!FOXF2;;chr7:27239740..27239759,-!p2@HOXA13!0.47!1.92!HOXA13;;chr7:73038839..73038862,-!p1@MLXIPL!0.47!1.92!MLXIPL;;chr9:102584278..102584285,+!p5@NR4A3!0.47!1.92!NR4A3;;chr14:55493763..55493824,-!p1@WDHD1!0.46!19.24!WDHD1;;chr10:104155480..104155534,+!p2@NFKB2!0.46!16.54!NFKB2;;chr18:45457423..45457468,-!p5@SMAD2!0.46!9.23!SMAD2;;chr1:23857325..23857416,-!p2@E2F2!0.46!2.31!E2F2;;chr6:20402070..20402082,+!p5@E2F3!0.46!2.31!E2F3;;chr16:29817789..29817838,+!p2@MAZ!0.44!33.86!MAZ;;chr2:178128149..178128198,-!p2@NFE2L2!0.44!12.70!NFE2L2;;chr1:45805813..45805859,+!p1@TOE1!0.44!10.77!TOE1;;chr12:3069037..3069119,+!p2@TEAD4!0.44!8.08!TEAD4;;chr2:239756671..239756732,+!p1@TWIST2!0.44!7.31!TWIST2;;chr8:67525473..67525518,-!p1@MYBL1!0.44!5.00!MYBL1;;chr1:249132462..249132481,+!p6@ZNF672!0.44!3.46!ZNF672;;chr1:212782094..212782109,+!p1@ATF3!0.43!66.56!ATF3;;chr6:144329384..144329405,-!p1@PLAGL1!0.43!27.70!PLAGL1;;chr19:45908292..45908374,-!p1@PPP1R13L!0.43!21.16!PPP1R13L;;chr14:62213827..62213853,+!p6@HIF1A!0.43!2.69!HIF1A;;chr9:99180662..99180690,-!p2@ZNF367!0.43!2.69!ZNF367;;chr2:74375081..74375092,-!p2@BOLA3!0.42!4.23!BOLA3;;chr3:24536253..24536328,-!p1@THRB!0.42!3.85!THRB;;chr4:87857474..87857489,+!p7@AFF1!0.42!3.46!AFF1;;chrX:70504244..70504278,+!p4@NONO!0.42!3.08!NONO;;chr16:54320101..54320125,-!p4@IRX3!0.42!2.69!IRX3;;chr16:54964740..54964789,+!p1@IRX5!0.42!2.69!IRX5;;chr16:54320617..54320643,-!p3@IRX3!0.42!2.31!IRX3;;chr7:1577111..1577132,+!p4@MAFK!0.42!1.92!MAFK;;chr12:2986206..2986258,-!p2@FOXM1!0.41!13.47!FOXM1;;chr16:1429627..1429662,-!p2@UNKL!0.41!6.16!UNKL;;chr1:8923998..8924033,-!p8@ENO1!0.41!3.46!ENO1;;chr11:3400442..3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| ||
|ffid_belonging_in_development=UBERON:0008947,UBERON:0002532,UBERON:0006595,UBERON:0010316 | |||
| | |||
|fonse_cell_line=FF:0101120 | |fonse_cell_line=FF:0101120 | ||
|fonse_cell_line_closure=FF:0101120 | |fonse_cell_line_closure=FF:0101120 | ||
Line 66: | Line 40: | ||
|fonse_treatment=FF:0000625,FF:0000632,FF:0000639,FF:0011134,FF:11896-125E6 | |fonse_treatment=FF:0000625,FF:0000632,FF:0000639,FF:0011134,FF:11896-125E6 | ||
|fonse_treatment_closure=FF:0000625,FF:0000632,FF:0000639,FF:0011134,FF:11896-125E6 | |fonse_treatment_closure=FF:0000625,FF:0000632,FF:0000639,FF:0011134,FF:11896-125E6 | ||
|top_motifs= | |has_quality= | ||
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|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/Hep-2%2520cells%2520treated%2520with%2520Streptococci%2520strain%2520JRS4%252c%2520biol_rep3.CNhs13499.11896-125E6.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/Hep-2%2520cells%2520treated%2520with%2520Streptococci%2520strain%2520JRS4%252c%2520biol_rep3.CNhs13499.11896-125E6.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/Hep-2%2520cells%2520treated%2520with%2520Streptococci%2520strain%2520JRS4%252c%2520biol_rep3.CNhs13499.11896-125E6.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/Hep-2%2520cells%2520treated%2520with%2520Streptococci%2520strain%2520JRS4%252c%2520biol_rep3.CNhs13499.11896-125E6.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11896-125E6 | |||
|is_a=EFO:0002091;;FF:0011134 | |||
|is_obsolete= | |||
|library_id=CNhs13499 | |||
|library_id_phase_based=2:CNhs13499 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11896 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11896 | |||
|name=Hep-2 cells treated with Streptococci strain JRS4, biol_rep3 | |||
|namespace= | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs13499,LSID1025,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
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| |||
|rna_box=125 | |||
|rna_catalog_number= | |||
|rna_concentration=0.72561 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number=2c | |||
|rna_od260/230=1.88 | |||
|rna_od260/280=2.03 | |||
|rna_position=E6 | |||
|rna_rin=9.6 | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=1.25E+08 | |||
|rna_weight_ug=10 | |||
|sample_age=56 | |||
|sample_category=cell lines | |||
|sample_cell_catalog= | |||
|sample_cell_line=Hep-2 | |||
|sample_cell_lot= | |||
|sample_cell_type=unclassifiable | |||
|sample_collaboration=Christine Wells (University of Queensland) | |||
|sample_company= | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=epidermoid carcinoma | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;2.41762735791166e-255!GO:0005737;cytoplasm;1.17306965284855e-207!GO:0043226;organelle;5.56670695710705e-206!GO:0043231;intracellular membrane-bound organelle;5.59867306117291e-206!GO:0043227;membrane-bound organelle;6.33135183403032e-206!GO:0043229;intracellular organelle;1.88702390121487e-205!GO:0044422;organelle part;1.32767519074683e-177!GO:0044446;intracellular organelle part;8.48487702971292e-176!GO:0044444;cytoplasmic part;8.09341634140671e-156!GO:0032991;macromolecular complex;9.31547591843565e-123!GO:0030529;ribonucleoprotein complex;2.01761617638227e-103!GO:0005739;mitochondrion;1.17336272588752e-101!GO:0044237;cellular metabolic process;5.13260051147602e-94!GO:0044238;primary metabolic process;9.11339977435743e-90!GO:0043233;organelle lumen;2.88041200854317e-88!GO:0031974;membrane-enclosed lumen;2.88041200854317e-88!GO:0044428;nuclear part;1.63784781457709e-87!GO:0003723;RNA binding;6.47961202002363e-84!GO:0043170;macromolecule metabolic process;8.94039808075238e-75!GO:0005634;nucleus;1.61947862763938e-74!GO:0005515;protein binding;7.26606550002809e-65!GO:0044429;mitochondrial part;1.02677565193833e-64!GO:0006396;RNA processing;3.86277046396479e-64!GO:0005840;ribosome;2.54636610539346e-62!GO:0043234;protein complex;5.09711285762722e-62!GO:0031090;organelle membrane;5.33004968089618e-60!GO:0006412;translation;3.07185632381703e-59!GO:0031967;organelle envelope;1.06407386631968e-56!GO:0031975;envelope;1.66013363125705e-56!GO:0003735;structural constituent of ribosome;6.58771859642026e-54!GO:0009058;biosynthetic process;7.19332869765628e-54!GO:0044249;cellular biosynthetic process;1.05124829047244e-53!GO:0031981;nuclear lumen;1.08044147618521e-50!GO:0016043;cellular component organization and biogenesis;3.42821994659645e-47!GO:0033279;ribosomal subunit;4.16056949666781e-47!GO:0019538;protein metabolic process;8.80407983146081e-46!GO:0006259;DNA metabolic process;2.22928409734959e-45!GO:0015031;protein transport;1.06094346428051e-43!GO:0016071;mRNA metabolic process;1.74901673392836e-43!GO:0005829;cytosol;2.22756469876716e-43!GO:0009059;macromolecule biosynthetic process;2.70217858868064e-43!GO:0033036;macromolecule localization;2.84528158998703e-43!GO:0043228;non-membrane-bound organelle;1.76737435168696e-41!GO:0043232;intracellular non-membrane-bound organelle;1.76737435168696e-41!GO:0005740;mitochondrial envelope;1.97880798740859e-41!GO:0008380;RNA splicing;3.26372246733063e-41!GO:0044260;cellular macromolecule metabolic process;2.12166674716442e-40!GO:0044267;cellular protein metabolic process;5.1345105542683e-40!GO:0045184;establishment of protein localization;8.04200606966743e-40!GO:0006397;mRNA processing;1.4880815084597e-39!GO:0019866;organelle inner membrane;1.58168569882474e-39!GO:0008104;protein localization;3.37449360028121e-39!GO:0031966;mitochondrial membrane;5.61073301053508e-39!GO:0022613;ribonucleoprotein complex biogenesis and assembly;2.00871341271971e-38!GO:0005743;mitochondrial inner membrane;2.44265530242724e-37!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.95205269987994e-37!GO:0043283;biopolymer metabolic process;7.50039772618199e-36!GO:0065003;macromolecular complex assembly;1.7599278745845e-35!GO:0006996;organelle organization and biogenesis;1.47486642045397e-34!GO:0046907;intracellular transport;4.04533545797188e-34!GO:0007049;cell cycle;9.59612902915762e-32!GO:0005830;cytosolic ribosome (sensu Eukaryota);2.07292216246745e-31!GO:0010467;gene expression;2.5453414508833e-31!GO:0022607;cellular component assembly;1.33775789915572e-30!GO:0005681;spliceosome;2.15025291479894e-30!GO:0005654;nucleoplasm;3.41367846680178e-29!GO:0006886;intracellular protein transport;3.64064942712074e-29!GO:0000166;nucleotide binding;7.56746814750757e-29!GO:0031980;mitochondrial lumen;7.69487040158064e-29!GO:0005759;mitochondrial matrix;7.69487040158064e-29!GO:0006974;response to DNA damage stimulus;4.90841245391028e-27!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;6.74217613694953e-27!GO:0016462;pyrophosphatase activity;7.81606693517582e-27!GO:0016817;hydrolase activity, acting on acid anhydrides;9.67266887438801e-27!GO:0044445;cytosolic part;2.34394673292171e-26!GO:0006119;oxidative phosphorylation;2.56237663809259e-26!GO:0044455;mitochondrial membrane part;3.54801468591173e-26!GO:0017111;nucleoside-triphosphatase activity;8.85582856744461e-26!GO:0015934;large ribosomal subunit;2.58744339767116e-25!GO:0005730;nucleolus;6.97754993670695e-25!GO:0000278;mitotic cell cycle;1.07317248416568e-23!GO:0051186;cofactor metabolic process;1.14297318145828e-23!GO:0022402;cell cycle process;2.16884079505506e-23!GO:0015935;small ribosomal subunit;5.27901256597233e-23!GO:0044451;nucleoplasm part;5.5316123504209e-23!GO:0006281;DNA repair;6.61179881481815e-23!GO:0012505;endomembrane system;8.63746832895876e-23!GO:0005694;chromosome;4.34397718701792e-22!GO:0051649;establishment of cellular localization;8.28872036033937e-22!GO:0005783;endoplasmic reticulum;1.16287877175796e-21!GO:0051641;cellular localization;1.31444287681012e-21!GO:0006457;protein folding;1.54948120245922e-21!GO:0006260;DNA replication;1.65510881231672e-21!GO:0016874;ligase activity;6.00500060253445e-21!GO:0009719;response to endogenous stimulus;6.86459498628071e-21!GO:0044427;chromosomal part;8.21991129761019e-21!GO:0005746;mitochondrial respiratory chain;4.45421311745559e-20!GO:0017076;purine nucleotide binding;9.97014325717352e-20!GO:0032553;ribonucleotide binding;1.05737395895977e-19!GO:0032555;purine ribonucleotide binding;1.05737395895977e-19!GO:0022618;protein-RNA complex assembly;1.27912332561755e-19!GO:0005761;mitochondrial ribosome;1.40195308567546e-19!GO:0000313;organellar ribosome;1.40195308567546e-19!GO:0044432;endoplasmic reticulum part;2.19338941307805e-19!GO:0042254;ribosome biogenesis and assembly;2.31751695318067e-19!GO:0006732;coenzyme metabolic process;6.25186580771688e-19!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.3745987210949e-18!GO:0022403;cell cycle phase;1.51606525271483e-18!GO:0016887;ATPase activity;4.90218294216347e-18!GO:0005524;ATP binding;6.14258682150556e-18!GO:0032559;adenyl ribonucleotide binding;7.24594717376856e-18!GO:0000087;M phase of mitotic cell cycle;7.63540706297145e-18!GO:0003676;nucleic acid binding;7.63540706297145e-18!GO:0042623;ATPase activity, coupled;8.51331431775626e-18!GO:0044248;cellular catabolic process;9.75176533933694e-18!GO:0000502;proteasome complex (sensu Eukaryota);1.01767985086462e-17!GO:0050136;NADH dehydrogenase (quinone) activity;1.06700728206539e-17!GO:0003954;NADH dehydrogenase activity;1.06700728206539e-17!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.06700728206539e-17!GO:0030554;adenyl nucleotide binding;1.1171075144967e-17!GO:0007067;mitosis;1.56009439387623e-17!GO:0044265;cellular macromolecule catabolic process;2.34478053495045e-17!GO:0008135;translation factor activity, nucleic acid binding;3.73017744234337e-17!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);7.2894523697379e-17!GO:0051276;chromosome organization and biogenesis;1.2132554570293e-16!GO:0006399;tRNA metabolic process;1.28730374657703e-16!GO:0044453;nuclear membrane part;3.60420900286389e-16!GO:0006512;ubiquitin cycle;5.01844556496936e-16!GO:0005635;nuclear envelope;6.53821807071545e-16!GO:0042775;organelle ATP synthesis coupled electron transport;6.62001084512551e-16!GO:0042773;ATP synthesis coupled electron transport;6.62001084512551e-16!GO:0030964;NADH dehydrogenase complex (quinone);1.0991711235204e-15!GO:0045271;respiratory chain complex I;1.0991711235204e-15!GO:0005747;mitochondrial respiratory chain complex I;1.0991711235204e-15!GO:0051082;unfolded protein binding;1.39735922874952e-15!GO:0051301;cell division;1.44508556115154e-15!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.73299255138971e-15!GO:0000398;nuclear mRNA splicing, via spliceosome;1.87589857752468e-15!GO:0000375;RNA splicing, via transesterification reactions;1.87589857752468e-15!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.87589857752468e-15!GO:0051603;proteolysis involved in cellular protein catabolic process;2.25013630704751e-15!GO:0006605;protein targeting;2.40687508237685e-15!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;3.35495792259363e-15!GO:0031965;nuclear membrane;3.65646118949591e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);3.98911351693496e-15!GO:0019941;modification-dependent protein catabolic process;4.17902100481331e-15!GO:0043632;modification-dependent macromolecule catabolic process;4.17902100481331e-15!GO:0005789;endoplasmic reticulum membrane;4.62338938141921e-15!GO:0000279;M phase;4.65102465531479e-15!GO:0044257;cellular protein catabolic process;5.79827587305556e-15!GO:0006511;ubiquitin-dependent protein catabolic process;1.01671023619934e-14!GO:0009057;macromolecule catabolic process;1.17776760078771e-14!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.52798915737893e-14!GO:0043285;biopolymer catabolic process;1.74858970717863e-14!GO:0048770;pigment granule;2.03780375613314e-14!GO:0042470;melanosome;2.03780375613314e-14!GO:0009055;electron carrier activity;2.09739501413317e-14!GO:0005643;nuclear pore;6.92384005356353e-14!GO:0003743;translation initiation factor activity;1.6878317411821e-13!GO:0051188;cofactor biosynthetic process;1.85567860363407e-13!GO:0008134;transcription factor binding;2.34151066155641e-13!GO:0006364;rRNA processing;2.52616180832088e-13!GO:0006325;establishment and/or maintenance of chromatin architecture;3.6790155504123e-13!GO:0048193;Golgi vesicle transport;4.4899032818131e-13!GO:0009259;ribonucleotide metabolic process;4.86774616088406e-13!GO:0016072;rRNA metabolic process;5.3252311299395e-13!GO:0006323;DNA packaging;1.20072954015226e-12!GO:0000074;regulation of progression through cell cycle;1.22887376525009e-12!GO:0065002;intracellular protein transport across a membrane;1.25373840305721e-12!GO:0051726;regulation of cell cycle;1.25373840305721e-12!GO:0006163;purine nucleotide metabolic process;1.31585264328263e-12!GO:0004386;helicase activity;1.65701794146816e-12!GO:0006413;translational initiation;1.71345630268501e-12!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;2.28747424716022e-12!GO:0050657;nucleic acid transport;2.38191169819675e-12!GO:0051236;establishment of RNA localization;2.38191169819675e-12!GO:0050658;RNA transport;2.38191169819675e-12!GO:0006403;RNA localization;2.59934681896938e-12!GO:0016491;oxidoreductase activity;4.13876303053946e-12!GO:0008026;ATP-dependent helicase activity;6.50253027795265e-12!GO:0046930;pore complex;6.77727137733113e-12!GO:0030163;protein catabolic process;7.13568572504761e-12!GO:0000785;chromatin;7.45627317943228e-12!GO:0016604;nuclear body;1.01318223578903e-11!GO:0006913;nucleocytoplasmic transport;1.1560893367509e-11!GO:0009150;purine ribonucleotide metabolic process;1.59759305351503e-11!GO:0009260;ribonucleotide biosynthetic process;2.1041287367228e-11!GO:0006333;chromatin assembly or disassembly;2.47600881732751e-11!GO:0009108;coenzyme biosynthetic process;2.57230683135795e-11!GO:0006164;purine nucleotide biosynthetic process;2.94235999850551e-11!GO:0005794;Golgi apparatus;3.48038474222422e-11!GO:0051169;nuclear transport;3.67598637186818e-11!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;4.5868371645393e-11!GO:0012501;programmed cell death;4.58910685460207e-11!GO:0009117;nucleotide metabolic process;5.26452487823033e-11!GO:0008565;protein transporter activity;6.32096447917157e-11!GO:0006915;apoptosis;6.73972440564751e-11!GO:0065004;protein-DNA complex assembly;6.86653208193259e-11!GO:0016879;ligase activity, forming carbon-nitrogen bonds;9.48353439500484e-11!GO:0016192;vesicle-mediated transport;1.10647974547269e-10!GO:0016787;hydrolase activity;1.11135148140475e-10!GO:0006261;DNA-dependent DNA replication;1.12610069691579e-10!GO:0051028;mRNA transport;1.55788848136191e-10!GO:0007005;mitochondrion organization and biogenesis;2.06148232506128e-10!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;2.07287519722878e-10!GO:0009056;catabolic process;2.43772621728844e-10!GO:0009199;ribonucleoside triphosphate metabolic process;2.50745164909932e-10!GO:0009060;aerobic respiration;2.8315623596962e-10!GO:0009141;nucleoside triphosphate metabolic process;2.8870536797415e-10!GO:0009152;purine ribonucleotide biosynthetic process;3.50741571621122e-10!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;3.55750711791747e-10!GO:0006446;regulation of translational initiation;3.91197665205847e-10!GO:0016779;nucleotidyltransferase activity;4.1781605254399e-10!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;4.42189464020843e-10!GO:0004812;aminoacyl-tRNA ligase activity;4.42189464020843e-10!GO:0016875;ligase activity, forming carbon-oxygen bonds;4.42189464020843e-10!GO:0016070;RNA metabolic process;4.84663483252347e-10!GO:0009205;purine ribonucleoside triphosphate metabolic process;6.13332907546388e-10!GO:0009144;purine nucleoside triphosphate metabolic process;6.13332907546388e-10!GO:0006461;protein complex assembly;6.47153353580859e-10!GO:0030532;small nuclear ribonucleoprotein complex;6.47443133888042e-10!GO:0043038;amino acid activation;7.3574000714219e-10!GO:0006418;tRNA aminoacylation for protein translation;7.3574000714219e-10!GO:0043039;tRNA aminoacylation;7.3574000714219e-10!GO:0008219;cell death;8.0128380809387e-10!GO:0016265;death;8.0128380809387e-10!GO:0045333;cellular respiration;9.4181695921365e-10!GO:0015986;ATP synthesis coupled proton transport;1.05921851732246e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.05921851732246e-09!GO:0043412;biopolymer modification;1.74233555076807e-09!GO:0046034;ATP metabolic process;1.78655746957993e-09!GO:0008639;small protein conjugating enzyme activity;1.9808759611445e-09!GO:0003697;single-stranded DNA binding;2.19520787561909e-09!GO:0009142;nucleoside triphosphate biosynthetic process;2.29087830281557e-09!GO:0009201;ribonucleoside triphosphate biosynthetic process;2.29087830281557e-09!GO:0016607;nuclear speck;3.2800784994871e-09!GO:0006334;nucleosome assembly;4.11130935869877e-09!GO:0043566;structure-specific DNA binding;4.34717484173571e-09!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;5.86406390923212e-09!GO:0009145;purine nucleoside triphosphate biosynthetic process;5.86406390923212e-09!GO:0004842;ubiquitin-protein ligase activity;6.00369023304512e-09!GO:0019787;small conjugating protein ligase activity;6.00708125576978e-09!GO:0017038;protein import;7.29465851028059e-09!GO:0006091;generation of precursor metabolites and energy;7.9586090065475e-09!GO:0016740;transferase activity;1.07048893888944e-08!GO:0031497;chromatin assembly;1.13189701075444e-08!GO:0019829;cation-transporting ATPase activity;1.17595711310614e-08!GO:0015078;hydrogen ion transmembrane transporter activity;1.37222517617847e-08!GO:0006754;ATP biosynthetic process;1.37973200171575e-08!GO:0006753;nucleoside phosphate metabolic process;1.37973200171575e-08!GO:0006084;acetyl-CoA metabolic process;1.4095557693929e-08!GO:0006099;tricarboxylic acid cycle;1.44179121720365e-08!GO:0046356;acetyl-CoA catabolic process;1.44179121720365e-08!GO:0006752;group transfer coenzyme metabolic process;1.59163205373016e-08!GO:0005819;spindle;2.3418585055196e-08!GO:0008033;tRNA processing;4.80273860692327e-08!GO:0016469;proton-transporting two-sector ATPase complex;4.92067865310934e-08!GO:0006366;transcription from RNA polymerase II promoter;5.02431480286922e-08!GO:0016881;acid-amino acid ligase activity;5.33158801771266e-08!GO:0005793;ER-Golgi intermediate compartment;7.49429991859181e-08!GO:0003712;transcription cofactor activity;8.35218666107823e-08!GO:0051329;interphase of mitotic cell cycle;1.04122547487975e-07!GO:0005657;replication fork;1.13050118586441e-07!GO:0051187;cofactor catabolic process;1.25400259043878e-07!GO:0051325;interphase;1.73316120397958e-07!GO:0008094;DNA-dependent ATPase activity;1.74832946120066e-07!GO:0000775;chromosome, pericentric region;1.76150450522914e-07!GO:0045259;proton-transporting ATP synthase complex;2.12953440082738e-07!GO:0015630;microtubule cytoskeleton;2.14745727343485e-07!GO:0006464;protein modification process;2.20014819882062e-07!GO:0009109;coenzyme catabolic process;2.76709690367016e-07!GO:0005768;endosome;2.91048664650716e-07!GO:0003899;DNA-directed RNA polymerase activity;3.01418225249978e-07!GO:0005762;mitochondrial large ribosomal subunit;3.01418225249978e-07!GO:0000315;organellar large ribosomal subunit;3.01418225249978e-07!GO:0042981;regulation of apoptosis;3.14029760643967e-07!GO:0043067;regulation of programmed cell death;3.14029760643967e-07!GO:0006888;ER to Golgi vesicle-mediated transport;3.39424449677893e-07!GO:0005839;proteasome core complex (sensu Eukaryota);4.53150287805699e-07!GO:0016568;chromatin modification;4.75258692004876e-07!GO:0000075;cell cycle checkpoint;5.27190185824458e-07!GO:0000245;spliceosome assembly;5.47978702757288e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;5.72073613380849e-07!GO:0008654;phospholipid biosynthetic process;6.10964193728113e-07!GO:0043623;cellular protein complex assembly;6.32796407294889e-07!GO:0030120;vesicle coat;6.32796407294889e-07!GO:0030662;coated vesicle membrane;6.32796407294889e-07!GO:0009165;nucleotide biosynthetic process;7.24480740694436e-07!GO:0032446;protein modification by small protein conjugation;1.13586600890059e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.16119697973724e-06!GO:0000079;regulation of cyclin-dependent protein kinase activity;1.44096402078287e-06!GO:0048475;coated membrane;1.63190232554345e-06!GO:0030117;membrane coat;1.63190232554345e-06!GO:0016567;protein ubiquitination;1.63190232554345e-06!GO:0007051;spindle organization and biogenesis;1.67950948719129e-06!GO:0016853;isomerase activity;1.80767926461041e-06!GO:0003724;RNA helicase activity;1.86291178374152e-06!GO:0006916;anti-apoptosis;1.92346823887977e-06!GO:0000314;organellar small ribosomal subunit;1.92937048041217e-06!GO:0005763;mitochondrial small ribosomal subunit;1.92937048041217e-06!GO:0004298;threonine endopeptidase activity;2.28090976899104e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;2.31014550118279e-06!GO:0043687;post-translational protein modification;2.46227608443189e-06!GO:0051427;hormone receptor binding;3.23024630784015e-06!GO:0043069;negative regulation of programmed cell death;3.23924962881266e-06!GO:0006082;organic acid metabolic process;3.27920712364965e-06!GO:0019752;carboxylic acid metabolic process;3.57670848684161e-06!GO:0005813;centrosome;4.19068972482265e-06!GO:0046483;heterocycle metabolic process;4.66277912450607e-06!GO:0043066;negative regulation of apoptosis;5.14122561494767e-06!GO:0005667;transcription factor complex;5.20777202889785e-06!GO:0000151;ubiquitin ligase complex;5.31144332661057e-06!GO:0006302;double-strand break repair;5.36246462510289e-06!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;6.66922724102028e-06!GO:0015399;primary active transmembrane transporter activity;6.66922724102028e-06!GO:0006613;cotranslational protein targeting to membrane;6.80410460138935e-06!GO:0051170;nuclear import;7.04439652469943e-06!GO:0035257;nuclear hormone receptor binding;7.79337606629891e-06!GO:0005815;microtubule organizing center;7.90301808911901e-06!GO:0044452;nucleolar part;8.10299150910616e-06!GO:0051168;nuclear export;8.45448102383311e-06!GO:0008168;methyltransferase activity;8.671875907629e-06!GO:0051246;regulation of protein metabolic process;9.20908163438818e-06!GO:0006414;translational elongation;9.83887470677689e-06!GO:0046474;glycerophospholipid biosynthetic process;1.01949071215475e-05!GO:0016741;transferase activity, transferring one-carbon groups;1.03301424487146e-05!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;1.10479009670762e-05!GO:0005788;endoplasmic reticulum lumen;1.13731127023136e-05!GO:0045454;cell redox homeostasis;1.16990578328262e-05!GO:0016126;sterol biosynthetic process;1.78843558671677e-05!GO:0000786;nucleosome;1.8936372764619e-05!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;1.9132989882425e-05!GO:0015980;energy derivation by oxidation of organic compounds;2.10923104258575e-05!GO:0007249;I-kappaB kinase/NF-kappaB cascade;2.28223885732293e-05!GO:0003924;GTPase activity;2.42279472603709e-05!GO:0006606;protein import into nucleus;2.5243153118047e-05!GO:0006626;protein targeting to mitochondrion;2.58909937969494e-05!GO:0008610;lipid biosynthetic process;3.08070654525879e-05!GO:0003682;chromatin binding;3.19445534794607e-05!GO:0005773;vacuole;3.19445534794607e-05!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;3.19445534794607e-05!GO:0051052;regulation of DNA metabolic process;3.65174769310826e-05!GO:0043021;ribonucleoprotein binding;3.97813117998553e-05!GO:0006839;mitochondrial transport;4.04629148830827e-05!GO:0006310;DNA recombination;4.4567592772339e-05!GO:0048523;negative regulation of cellular process;4.5452028683036e-05!GO:0046489;phosphoinositide biosynthetic process;4.91975773738539e-05!GO:0008186;RNA-dependent ATPase activity;4.97944495220243e-05!GO:0007088;regulation of mitosis;5.21265236301665e-05!GO:0043681;protein import into mitochondrion;5.43145004450969e-05!GO:0050662;coenzyme binding;5.80653246704266e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;6.13742666390704e-05!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;6.13867529897244e-05!GO:0006695;cholesterol biosynthetic process;6.43268489913689e-05!GO:0031324;negative regulation of cellular metabolic process;6.60364587060697e-05!GO:0003690;double-stranded DNA binding;6.8870155802561e-05!GO:0003713;transcription coactivator activity;7.05943530326845e-05!GO:0030867;rough endoplasmic reticulum membrane;7.30831047360922e-05!GO:0044440;endosomal part;7.67452349137791e-05!GO:0010008;endosome membrane;7.67452349137791e-05!GO:0005753;mitochondrial proton-transporting ATP synthase complex;7.83501150031437e-05!GO:0000776;kinetochore;8.66478910997528e-05!GO:0005852;eukaryotic translation initiation factor 3 complex;8.84269986973885e-05!GO:0019867;outer membrane;8.84415030567534e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000110788225198034!GO:0031968;organelle outer membrane;0.000112917246131136!GO:0005770;late endosome;0.000116189561826935!GO:0000323;lytic vacuole;0.000121337895266229!GO:0005764;lysosome;0.000121337895266229!GO:0004004;ATP-dependent RNA helicase activity;0.00013815255853128!GO:0016859;cis-trans isomerase activity;0.000154083690952999!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.00016097143274943!GO:0000059;protein import into nucleus, docking;0.00017123642596968!GO:0043284;biopolymer biosynthetic process;0.000175143536241015!GO:0004518;nuclease activity;0.000178599398839496!GO:0003678;DNA helicase activity;0.000179641201294634!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.00019043014810264!GO:0004527;exonuclease activity;0.000190761373297149!GO:0044431;Golgi apparatus part;0.00019354167952892!GO:0006383;transcription from RNA polymerase III promoter;0.000197612929235096!GO:0048037;cofactor binding;0.000216629889556945!GO:0006118;electron transport;0.000224851979843139!GO:0045786;negative regulation of progression through cell cycle;0.000230471026545092!GO:0006612;protein targeting to membrane;0.000235025369514189!GO:0042802;identical protein binding;0.000247337884254801!GO:0006793;phosphorus metabolic process;0.00024756588233848!GO:0006796;phosphate metabolic process;0.00024756588233848!GO:0003684;damaged DNA binding;0.00024756588233848!GO:0043492;ATPase activity, coupled to movement of substances;0.000269017904869617!GO:0005798;Golgi-associated vesicle;0.00028654253965414!GO:0009112;nucleobase metabolic process;0.000315632739700927!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000322209882777002!GO:0005525;GTP binding;0.000325444256653192!GO:0009892;negative regulation of metabolic process;0.000326893959282165!GO:0019843;rRNA binding;0.000332507334856629!GO:0006650;glycerophospholipid metabolic process;0.000333894571803265!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000334269068518708!GO:0007059;chromosome segregation;0.000341603276944427!GO:0043596;nuclear replication fork;0.000362524048328287!GO:0033116;ER-Golgi intermediate compartment membrane;0.000366169905156422!GO:0006950;response to stress;0.000379108332524843!GO:0005048;signal sequence binding;0.000379108332524843!GO:0030880;RNA polymerase complex;0.000379889500360179!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000382856459582092!GO:0031072;heat shock protein binding;0.000390586781558057!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000423261248433789!GO:0003729;mRNA binding;0.000423723493767133!GO:0005791;rough endoplasmic reticulum;0.000430566493445618!GO:0015992;proton transport;0.000442336081655391!GO:0005741;mitochondrial outer membrane;0.000456702080094236!GO:0046467;membrane lipid biosynthetic process;0.00047392227900556!GO:0051540;metal cluster binding;0.000475725018594499!GO:0051536;iron-sulfur cluster binding;0.000475725018594499!GO:0051920;peroxiredoxin activity;0.000486880192991691!GO:0006275;regulation of DNA replication;0.000512946698646121!GO:0006818;hydrogen transport;0.000512946698646121!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.0005284340464312!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.000555527905282662!GO:0051789;response to protein stimulus;0.000555527905282662!GO:0006986;response to unfolded protein;0.000555527905282662!GO:0005684;U2-dependent spliceosome;0.000566847713482056!GO:0006520;amino acid metabolic process;0.000573459893570497!GO:0006506;GPI anchor biosynthetic process;0.000591200183295307!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.000612698303229636!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.000612698303229636!GO:0016563;transcription activator activity;0.000631142957865107!GO:0006270;DNA replication initiation;0.000634645610761405!GO:0016310;phosphorylation;0.000663172198963369!GO:0000049;tRNA binding;0.000665056543964397!GO:0044262;cellular carbohydrate metabolic process;0.000684276220720753!GO:0008361;regulation of cell size;0.000701913507934463!GO:0016363;nuclear matrix;0.000704814056575658!GO:0007006;mitochondrial membrane organization and biogenesis;0.000714415684315602!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00073035537223611!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00073035537223611!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00073035537223611!GO:0009116;nucleoside metabolic process;0.000741938809088729!GO:0032508;DNA duplex unwinding;0.000742436629772124!GO:0032392;DNA geometric change;0.000742436629772124!GO:0006767;water-soluble vitamin metabolic process;0.000749941174559253!GO:0048519;negative regulation of biological process;0.00077271620769533!GO:0005885;Arp2/3 protein complex;0.000786570216119281!GO:0048471;perinuclear region of cytoplasm;0.000805322941537772!GO:0016049;cell growth;0.000806970129427513!GO:0065009;regulation of a molecular function;0.000862803515100318!GO:0030176;integral to endoplasmic reticulum membrane;0.000881152273682835!GO:0016564;transcription repressor activity;0.000894204278399495!GO:0001558;regulation of cell growth;0.000902808602592941!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.000910337828852078!GO:0000428;DNA-directed RNA polymerase complex;0.000910337828852078!GO:0006505;GPI anchor metabolic process;0.000984462420291516!GO:0051287;NAD binding;0.00101487803647518!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.00102270437296158!GO:0006733;oxidoreduction coenzyme metabolic process;0.00102926139553261!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00115158180523696!GO:0007052;mitotic spindle organization and biogenesis;0.00117730502092843!GO:0031988;membrane-bound vesicle;0.00122118928380858!GO:0007093;mitotic cell cycle checkpoint;0.00132131921421297!GO:0000139;Golgi membrane;0.00137946419588468!GO:0048500;signal recognition particle;0.00138889150959177!GO:0003711;transcription elongation regulator activity;0.00139239595914301!GO:0008312;7S RNA binding;0.00142765935062756!GO:0006284;base-excision repair;0.00143660381572443!GO:0006007;glucose catabolic process;0.00146141061944554!GO:0051087;chaperone binding;0.00147684651524559!GO:0016023;cytoplasmic membrane-bound vesicle;0.00150924294215417!GO:0031252;leading edge;0.00151790421069562!GO:0008408;3'-5' exonuclease activity;0.0015444921424205!GO:0016272;prefoldin complex;0.00154968259145471!GO:0035258;steroid hormone receptor binding;0.00154968259145471!GO:0006405;RNA export from nucleus;0.00155489077064342!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00157275348678983!GO:0030132;clathrin coat of coated pit;0.00159728505701442!GO:0006268;DNA unwinding during replication;0.00160089273636349!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00162397287413669!GO:0030384;phosphoinositide metabolic process;0.00172778613238971!GO:0009451;RNA modification;0.001791869909472!GO:0008180;signalosome;0.00184711269900564!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.00190026505463387!GO:0005876;spindle microtubule;0.00190026505463387!GO:0030663;COPI coated vesicle membrane;0.0019147546371581!GO:0030126;COPI vesicle coat;0.0019147546371581!GO:0006611;protein export from nucleus;0.00207741634689264!GO:0005769;early endosome;0.00211058500215461!GO:0016628;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;0.00211355970945806!GO:0043601;nuclear replisome;0.00211355970945806!GO:0030894;replisome;0.00211355970945806!GO:0000086;G2/M transition of mitotic cell cycle;0.00215840252344594!GO:0042393;histone binding;0.00228244667410553!GO:0006891;intra-Golgi vesicle-mediated transport;0.00234879360669713!GO:0006497;protein amino acid lipidation;0.00237348994852801!GO:0032561;guanyl ribonucleotide binding;0.00239758440654847!GO:0019001;guanyl nucleotide binding;0.00239758440654847!GO:0016125;sterol metabolic process;0.00240991350476117!GO:0048487;beta-tubulin binding;0.00243903419434381!GO:0042770;DNA damage response, signal transduction;0.00246299389287243!GO:0003746;translation elongation factor activity;0.00247703828901906!GO:0006352;transcription initiation;0.00249163233293128!GO:0006595;polyamine metabolic process;0.00255116323091105!GO:0000082;G1/S transition of mitotic cell cycle;0.00270203836812253!GO:0006144;purine base metabolic process;0.00279440472569154!GO:0006401;RNA catabolic process;0.00285056787413531!GO:0030118;clathrin coat;0.00291697121846852!GO:0008632;apoptotic program;0.00292521230794559!GO:0006066;alcohol metabolic process;0.00297977386522801!GO:0000096;sulfur amino acid metabolic process;0.00301243275378936!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00301243275378936!GO:0015002;heme-copper terminal oxidase activity;0.00301243275378936!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00301243275378936!GO:0004129;cytochrome-c oxidase activity;0.00301243275378936!GO:0022890;inorganic cation transmembrane transporter activity;0.00302888610258017!GO:0044255;cellular lipid metabolic process;0.00305290412638849!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00316488930572934!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00320560093893322!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00333279707885416!GO:0045047;protein targeting to ER;0.00333279707885416!GO:0004532;exoribonuclease activity;0.00341699461992177!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00341699461992177!GO:0006519;amino acid and derivative metabolic process;0.00349228779106856!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00362454436285055!GO:0000178;exosome (RNase complex);0.00363823279027596!GO:0005905;coated pit;0.00368042224884465!GO:0005637;nuclear inner membrane;0.00377671340536489!GO:0008320;protein transmembrane transporter activity;0.00403173429964002!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00426355606525299!GO:0005758;mitochondrial intermembrane space;0.00428493491739622!GO:0030137;COPI-coated vesicle;0.00438364199351035!GO:0016616;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;0.00449386525408729!GO:0000287;magnesium ion binding;0.00451621206375994!GO:0051252;regulation of RNA metabolic process;0.00451621206375994!GO:0031982;vesicle;0.00462794662237636!GO:0016614;oxidoreductase activity, acting on CH-OH group of donors;0.00487175973012163!GO:0048522;positive regulation of cellular process;0.00498004517603786!GO:0006778;porphyrin metabolic process;0.00515635353110351!GO:0033013;tetrapyrrole metabolic process;0.00515635353110351!GO:0016408;C-acyltransferase activity;0.00526345863071501!GO:0051539;4 iron, 4 sulfur cluster binding;0.00535425785482251!GO:0016044;membrane organization and biogenesis;0.00538679718130272!GO:0008022;protein C-terminus binding;0.00558111540818369!GO:0016481;negative regulation of transcription;0.00572716990894128!GO:0003725;double-stranded RNA binding;0.0057962141562157!GO:0006979;response to oxidative stress;0.00586671614334121!GO:0031410;cytoplasmic vesicle;0.00642393597373612!GO:0009124;nucleoside monophosphate biosynthetic process;0.00656135514133036!GO:0009123;nucleoside monophosphate metabolic process;0.00656135514133036!GO:0006509;membrane protein ectodomain proteolysis;0.00657370256717816!GO:0033619;membrane protein proteolysis;0.00657370256717816!GO:0003714;transcription corepressor activity;0.00673436703906798!GO:0000922;spindle pole;0.00697578439620283!GO:0004003;ATP-dependent DNA helicase activity;0.00709806233269587!GO:0022884;macromolecule transmembrane transporter activity;0.00709872860139332!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.00709872860139332!GO:0050790;regulation of catalytic activity;0.00726648026988223!GO:0004549;tRNA-specific ribonuclease activity;0.00751122546014826!GO:0006400;tRNA modification;0.00754868881501552!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.00757269397857792!GO:0030658;transport vesicle membrane;0.00760966703780681!GO:0008139;nuclear localization sequence binding;0.00761437422824574!GO:0006402;mRNA catabolic process;0.00774580326629229!GO:0030119;AP-type membrane coat adaptor complex;0.00778018591291523!GO:0008637;apoptotic mitochondrial changes;0.00794335888903078!GO:0031570;DNA integrity checkpoint;0.00809212555867212!GO:0043022;ribosome binding;0.00809743828670112!GO:0042158;lipoprotein biosynthetic process;0.00810696243007063!GO:0000725;recombinational repair;0.00825295827747581!GO:0000724;double-strand break repair via homologous recombination;0.00825295827747581!GO:0006730;one-carbon compound metabolic process;0.00826305304857978!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.00871334036643399!GO:0004526;ribonuclease P activity;0.00872773180548164!GO:0005832;chaperonin-containing T-complex;0.00872773180548164!GO:0043154;negative regulation of caspase activity;0.00875234824363521!GO:0040008;regulation of growth;0.00891343240458684!GO:0006338;chromatin remodeling;0.00918651712190272!GO:0009119;ribonucleoside metabolic process;0.00920744186971465!GO:0032259;methylation;0.00930401424577557!GO:0009303;rRNA transcription;0.00943139953892885!GO:0006807;nitrogen compound metabolic process;0.00978193793135607!GO:0008234;cysteine-type peptidase activity;0.0102307726419677!GO:0043414;biopolymer methylation;0.0103043141069947!GO:0004540;ribonuclease activity;0.0103043141069947!GO:0000339;RNA cap binding;0.0104542962460207!GO:0045792;negative regulation of cell size;0.0104700304833398!GO:0030131;clathrin adaptor complex;0.0105500049835157!GO:0051338;regulation of transferase activity;0.0107791819910181!GO:0006096;glycolysis;0.0112031614013396!GO:0030308;negative regulation of cell growth;0.0112063416867359!GO:0031124;mRNA 3'-end processing;0.0112249428650936!GO:0016251;general RNA polymerase II transcription factor activity;0.0112650137380374!GO:0008629;induction of apoptosis by intracellular signals;0.0114941004577889!GO:0007243;protein kinase cascade;0.0116417370016135!GO:0000175;3'-5'-exoribonuclease activity;0.0120892295358448!GO:0005874;microtubule;0.012131588137415!GO:0016407;acetyltransferase activity;0.0124856536031156!GO:0006289;nucleotide-excision repair;0.0130584344472068!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0131838616926346!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0132458115590384!GO:0008299;isoprenoid biosynthetic process;0.0134964411196457!GO:0030660;Golgi-associated vesicle membrane;0.0137638563226629!GO:0046966;thyroid hormone receptor binding;0.0137822385442012!GO:0031970;organelle envelope lumen;0.0139962540508139!GO:0000228;nuclear chromosome;0.0140843073373512!GO:0005862;muscle thin filament tropomyosin;0.014106525230619!GO:0006779;porphyrin biosynthetic process;0.0142376543663022!GO:0033014;tetrapyrrole biosynthetic process;0.0142376543663022!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0145573943357558!GO:0009161;ribonucleoside monophosphate metabolic process;0.0145573943357558!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.0145573943357558!GO:0030659;cytoplasmic vesicle membrane;0.0149395792632498!GO:0043549;regulation of kinase activity;0.0151759444445532!GO:0008652;amino acid biosynthetic process;0.0151759444445532!GO:0006740;NADPH regeneration;0.0151759444445532!GO:0006098;pentose-phosphate shunt;0.0151759444445532!GO:0004523;ribonuclease H activity;0.0153354037000004!GO:0030125;clathrin vesicle coat;0.0154290888574582!GO:0030665;clathrin coated vesicle membrane;0.0154290888574582!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0154628264360238!GO:0043189;H4/H2A histone acetyltransferase complex;0.015490643544828!GO:0006769;nicotinamide metabolic process;0.015558183512548!GO:0051053;negative regulation of DNA metabolic process;0.0155984546555504!GO:0043624;cellular protein complex disassembly;0.0156705464407304!GO:0044438;microbody part;0.0159553212029051!GO:0044439;peroxisomal part;0.0159553212029051!GO:0009308;amine metabolic process;0.0159553212029051!GO:0005996;monosaccharide metabolic process;0.0160572381220646!GO:0008203;cholesterol metabolic process;0.0161991135484975!GO:0005663;DNA replication factor C complex;0.0162076152839127!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0167635230860509!GO:0050178;phenylpyruvate tautomerase activity;0.0168291497400419!GO:0030521;androgen receptor signaling pathway;0.0168882956819288!GO:0006629;lipid metabolic process;0.0171814330294076!GO:0042168;heme metabolic process;0.0173345345630204!GO:0031902;late endosome membrane;0.0173345345630204!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0175105467502988!GO:0045039;protein import into mitochondrial inner membrane;0.0175105467502988!GO:0009003;signal peptidase activity;0.0175486717098434!GO:0006541;glutamine metabolic process;0.0176111515844112!GO:0008538;proteasome activator activity;0.0185477968865382!GO:0007034;vacuolar transport;0.0186180329269578!GO:0007021;tubulin folding;0.0186379210220642!GO:0006360;transcription from RNA polymerase I promoter;0.0186995950057772!GO:0006354;RNA elongation;0.0187026855219079!GO:0048146;positive regulation of fibroblast proliferation;0.0189406944035969!GO:0015631;tubulin binding;0.0190511052503813!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0190511052503813!GO:0019318;hexose metabolic process;0.0193192570078161!GO:0048144;fibroblast proliferation;0.0193585806609499!GO:0048145;regulation of fibroblast proliferation;0.0193585806609499!GO:0046365;monosaccharide catabolic process;0.0193587263197722!GO:0045045;secretory pathway;0.0193587263197722!GO:0006378;mRNA polyadenylation;0.019423365283024!GO:0000070;mitotic sister chromatid segregation;0.0196328002513344!GO:0043433;negative regulation of transcription factor activity;0.0197698384673733!GO:0000726;non-recombinational repair;0.0198798261334167!GO:0050681;androgen receptor binding;0.0201451285902426!GO:0007017;microtubule-based process;0.0203027872720482!GO:0005869;dynactin complex;0.0206343834332081!GO:0000030;mannosyltransferase activity;0.0208170826734697!GO:0016788;hydrolase activity, acting on ester bonds;0.0209190563769933!GO:0006006;glucose metabolic process;0.0213681829798639!GO:0000819;sister chromatid segregation;0.021403481645481!GO:0007010;cytoskeleton organization and biogenesis;0.0215967003234293!GO:0035267;NuA4 histone acetyltransferase complex;0.0217103083192159!GO:0032200;telomere organization and biogenesis;0.0217344154572732!GO:0000723;telomere maintenance;0.0217344154572732!GO:0030133;transport vesicle;0.0217811471436209!GO:0000152;nuclear ubiquitin ligase complex;0.0219863445407633!GO:0003923;GPI-anchor transamidase activity;0.0220517286617937!GO:0016255;attachment of GPI anchor to protein;0.0220517286617937!GO:0042765;GPI-anchor transamidase complex;0.0220517286617937!GO:0051059;NF-kappaB binding;0.0220886046582304!GO:0004860;protein kinase inhibitor activity;0.0220992131206699!GO:0043488;regulation of mRNA stability;0.0220992131206699!GO:0043487;regulation of RNA stability;0.0220992131206699!GO:0045859;regulation of protein kinase activity;0.0225872245916846!GO:0019899;enzyme binding;0.0227673648504201!GO:0005853;eukaryotic translation elongation factor 1 complex;0.0228941298381951!GO:0030508;thiol-disulfide exchange intermediate activity;0.0229212357658528!GO:0022406;membrane docking;0.0233090028147338!GO:0048278;vesicle docking;0.0233090028147338!GO:0031903;microbody membrane;0.0233090028147338!GO:0005778;peroxisomal membrane;0.0233090028147338!GO:0006376;mRNA splice site selection;0.0233090028147338!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0233090028147338!GO:0008250;oligosaccharyl transferase complex;0.0233829435966951!GO:0019362;pyridine nucleotide metabolic process;0.0233829435966951!GO:0006220;pyrimidine nucleotide metabolic process;0.0234290502340038!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0234806812462219!GO:0010257;NADH dehydrogenase complex assembly;0.0234806812462219!GO:0033108;mitochondrial respiratory chain complex assembly;0.0234806812462219!GO:0043065;positive regulation of apoptosis;0.0237351313289461!GO:0042364;water-soluble vitamin biosynthetic process;0.0238165686492871!GO:0004576;oligosaccharyl transferase activity;0.0241851099901108!GO:0007040;lysosome organization and biogenesis;0.0244240829780411!GO:0016197;endosome transport;0.0249784284888135!GO:0030134;ER to Golgi transport vesicle;0.0250483425434208!GO:0005744;mitochondrial inner membrane presequence translocase complex;0.0252863061797479!GO:0046164;alcohol catabolic process;0.0254594053379447!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0254594053379447!GO:0032984;macromolecular complex disassembly;0.0254594053379447!GO:0006643;membrane lipid metabolic process;0.0257362200639189!GO:0006596;polyamine biosynthetic process;0.0258728052650925!GO:0006213;pyrimidine nucleoside metabolic process;0.0261077210533859!GO:0006417;regulation of translation;0.0264083631401055!GO:0046112;nucleobase biosynthetic process;0.0266671852661022!GO:0046519;sphingoid metabolic process;0.0268028684405794!GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;0.0268623031135093!GO:0005777;peroxisome;0.0270702033155553!GO:0042579;microbody;0.0270702033155553!GO:0005774;vacuolar membrane;0.0272943158231994!GO:0005732;small nucleolar ribonucleoprotein complex;0.0272943158231994!GO:0012506;vesicle membrane;0.0274431044378795!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0274840397978996!GO:0046982;protein heterodimerization activity;0.0274913071934981!GO:0046128;purine ribonucleoside metabolic process;0.0277389161508917!GO:0042278;purine nucleoside metabolic process;0.0277389161508917!GO:0046983;protein dimerization activity;0.0277723007439678!GO:0043068;positive regulation of programmed cell death;0.0280567714717859!GO:0031123;RNA 3'-end processing;0.0292058366859671!GO:0044433;cytoplasmic vesicle part;0.0295085099745582!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.0296260044947654!GO:0031529;ruffle organization and biogenesis;0.0297918930060473!GO:0019320;hexose catabolic process;0.0300081981655789!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0305009800532715!GO:0000781;chromosome, telomeric region;0.0306979235265938!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0318892182823056!GO:0006518;peptide metabolic process;0.0318892182823056!GO:0009081;branched chain family amino acid metabolic process;0.0318892182823056!GO:0006904;vesicle docking during exocytosis;0.0318892182823056!GO:0042769;DNA damage response, detection of DNA damage;0.0326134828877452!GO:0009225;nucleotide-sugar metabolic process;0.0326428943940268!GO:0031406;carboxylic acid binding;0.0327175894990369!GO:0005658;alpha DNA polymerase:primase complex;0.0328084192298037!GO:0000077;DNA damage checkpoint;0.032839553209006!GO:0044454;nuclear chromosome part;0.0332021917223423!GO:0017166;vinculin binding;0.0334063570677072!GO:0003857;3-hydroxyacyl-CoA dehydrogenase activity;0.0336290288169123!GO:0030127;COPII vesicle coat;0.0339038746180922!GO:0012507;ER to Golgi transport vesicle membrane;0.0339038746180922!GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors;0.0339038746180922!GO:0005669;transcription factor TFIID complex;0.0339038746180922!GO:0051716;cellular response to stimulus;0.0339889020022212!GO:0016790;thiolester hydrolase activity;0.0341592616231972!GO:0000123;histone acetyltransferase complex;0.0352854914871001!GO:0043241;protein complex disassembly;0.0353856792383158!GO:0004448;isocitrate dehydrogenase activity;0.035533389105525!GO:0006308;DNA catabolic process;0.0356478091889882!GO:0008156;negative regulation of DNA replication;0.0359500894272008!GO:0006739;NADP metabolic process;0.036206775554956!GO:0016453;C-acetyltransferase activity;0.0362624646464479!GO:0015036;disulfide oxidoreductase activity;0.0362990117596671!GO:0001836;release of cytochrome c from mitochondria;0.0364586320151375!GO:0022411;cellular component disassembly;0.0364586320151375!GO:0030503;regulation of cell redox homeostasis;0.0367418260947067!GO:0006672;ceramide metabolic process;0.0370369610076852!GO:0019206;nucleoside kinase activity;0.0371582914663849!GO:0016835;carbon-oxygen lyase activity;0.0373636606117117!GO:0006749;glutathione metabolic process;0.037449553869141!GO:0005784;translocon complex;0.0380296526841009!GO:0016417;S-acyltransferase activity;0.0382942607274617!GO:0004659;prenyltransferase activity;0.0386669316885223!GO:0031371;ubiquitin conjugating enzyme complex;0.0387473272882953!GO:0007346;regulation of progression through mitotic cell cycle;0.0388642990967108!GO:0007050;cell cycle arrest;0.0390278576713492!GO:0007033;vacuole organization and biogenesis;0.039137022684296!GO:0031326;regulation of cellular biosynthetic process;0.0392246155462005!GO:0008601;protein phosphatase type 2A regulator activity;0.0396368193207122!GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;0.0396537699470137!GO:0019783;small conjugating protein-specific protease activity;0.0399714985706549!GO:0003985;acetyl-CoA C-acetyltransferase activity;0.0401372922797266!GO:0050811;GABA receptor binding;0.0421656359195328!GO:0030677;ribonuclease P complex;0.0421656359195328!GO:0031577;spindle checkpoint;0.0426047144434634!GO:0006644;phospholipid metabolic process;0.0426775076468186!GO:0031227;intrinsic to endoplasmic reticulum membrane;0.0427971018577753!GO:0009889;regulation of biosynthetic process;0.044091559737467!GO:0030433;ER-associated protein catabolic process;0.044464400400943!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.044464400400943!GO:0017056;structural constituent of nuclear pore;0.0445058247546225!GO:0005971;ribonucleoside-diphosphate reductase complex;0.0446167851500677!GO:0006783;heme biosynthetic process;0.0448252079350923!GO:0030911;TPR domain binding;0.0448252079350923!GO:0008173;RNA methyltransferase activity;0.0448353661075774!GO:0003756;protein disulfide isomerase activity;0.0448906425271948!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0448906425271948!GO:0009066;aspartate family amino acid metabolic process;0.0449007540839555!GO:0040029;regulation of gene expression, epigenetic;0.0451241337070811!GO:0007041;lysosomal transport;0.0454395932782645!GO:0030032;lamellipodium biogenesis;0.0464607847998592!GO:0000097;sulfur amino acid biosynthetic process;0.0466722430400461!GO:0007004;telomere maintenance via telomerase;0.0466937728321718!GO:0004861;cyclin-dependent protein kinase inhibitor activity;0.0467527360553508!GO:0005754;mitochondrial proton-transporting ATP synthase, catalytic core;0.0467527360553508!GO:0000275;mitochondrial proton-transporting ATP synthase complex, catalytic core F(1);0.0467527360553508!GO:0045267;proton-transporting ATP synthase, catalytic core;0.0467527360553508!GO:0008536;Ran GTPase binding;0.0481085203698301!GO:0030027;lamellipodium;0.0481725843163851!GO:0050750;low-density lipoprotein receptor binding;0.0481837951976848!GO:0005975;carbohydrate metabolic process;0.0484195846503266!GO:0003702;RNA polymerase II transcription factor activity;0.0487011227683552!GO:0004177;aminopeptidase activity;0.0487679762094339!GO:0044437;vacuolar part;0.0491219946154894 | |||
|sample_id=11896 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue= | |||
|top_motifs=ESRRA:1.86248839871;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.7390907079;PPARG:1.63215805797;HES1:1.58500911002;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.5752529006;E2F1..5:1.56929398055;FOXM1:1.39421945517;NR5A1,2:1.28255545967;ELK1,4_GABP{A,B1}:1.18770515853;FOXQ1:1.13261384624;YY1:0.997614625131;bHLH_family:0.831316974252;FOXN1:0.754792402688;NRF1:0.740816926278;NR6A1:0.731997661223;PAX8:0.707827628405;NKX3-1:0.699796016955;MYB:0.666081308914;HOX{A6,A7,B6,B7}:0.652718517127;HIF1A:0.648179948692;NFY{A,B,C}:0.646232658876;PAX1,9:0.64410205857;PAX5:0.644101714842;HNF4A_NR2F1,2:0.639023635174;ARID5B:0.616084063431;HOXA9_MEIS1:0.602672584121;ZNF143:0.566445022769;CREB1:0.55764098358;POU1F1:0.554564454952;GCM1,2:0.523959422643;EP300:0.505362351454;NKX3-2:0.496400031793;SNAI1..3:0.469385710638;ZEB1:0.459405404609;LEF1_TCF7_TCF7L1,2:0.391784572962;IRF7:0.349794326131;TBX4,5:0.339978860671;IKZF1:0.33748103118;ALX1:0.322842375428;GFI1:0.319898193415;FOX{F1,F2,J1}:0.309981194126;FOXD3:0.307423083018;TEAD1:0.304008515469;UFEwm:0.274361973746;ZNF148:0.271024938889;PDX1:0.26669207568;MYOD1:0.265700889472;TP53:0.244284799276;PAX2:0.197703552853;ATF5_CREB3:0.18831326365;HLF:0.159038433675;NFE2L1:0.147581294606;ZBTB16:0.142496515685;VSX1,2:0.118762020676;HSF1,2:0.118435829074;GFI1B:0.111427148587;HOX{A5,B5}:0.106065640727;PAX3,7:0.105032802875;STAT5{A,B}:0.0906725838824;BACH2:0.0800196761053;NANOG:0.0622206517278;ONECUT1,2:0.0579448438128;LHX3,4:0.0560130523313;ATF6:0.0534931896222;NFE2:0.0496793575842;PAX4:0.041252383219;CUX2:0.0405113384999;RORA:0.0299556835015;OCT4_SOX2{dimer}:0.0207230402247;NR3C1:0.012279031095;ZNF423:0.000144463227079;TFDP1:-0.00254373317081;CDX1,2,4:-0.014366090772;PRRX1,2:-0.0172398188364;PITX1..3:-0.0302242377374;FOS_FOS{B,L1}_JUN{B,D}:-0.0388208617707;MYBL2:-0.0390773840808;PBX1:-0.0501136517204;ALX4:-0.0515958467604;CDC5L:-0.0562854499129;HAND1,2:-0.059875092564;HNF1A:-0.0636352481454;NFE2L2:-0.0650710439108;RXR{A,B,G}:-0.0699595740251;AHR_ARNT_ARNT2:-0.0809970546272;GTF2A1,2:-0.0818407751011;BREu{core}:-0.0880193787657;MEF2{A,B,C,D}:-0.0960019869584;HOX{A4,D4}:-0.097530679401;TBP:-0.128870249928;MAFB:-0.13421604669;ESR1:-0.137865781791;TLX1..3_NFIC{dimer}:-0.143441387458;TEF:-0.144120193483;MTF1:-0.16749102535;IKZF2:-0.180574678624;ATF4:-0.181908141354;RFX2..5_RFXANK_RFXAP:-0.199825358749;SOX{8,9,10}:-0.215058671001;NFIL3:-0.232674887838;ZBTB6:-0.244307935822;GLI1..3:-0.256826042682;LMO2:-0.257990414999;NFKB1_REL_RELA:-0.259789206718;FOXA2:-0.267238588621;FOSL2:-0.269503720913;ELF1,2,4:-0.274787949646;NKX2-2,8:-0.278810234454;NKX6-1,2:-0.284601477753;GZF1:-0.304735363647;PAX6:-0.306407427952;FOX{I1,J2}:-0.308304577953;POU3F1..4:-0.312571261033;CEBPA,B_DDIT3:-0.324760000012;T:-0.341790694616;JUN:-0.348621625835;RXRA_VDR{dimer}:-0.349147883795;NR1H4:-0.352660466046;KLF4:-0.354288787917;TFCP2:-0.361384440193;RFX1:-0.365820996854;STAT2,4,6:-0.371890423009;GATA6:-0.381746056397;EN1,2:-0.386136630658;SREBF1,2:-0.402756652526;DBP:-0.468124699849;CRX:-0.469680846239;SOX17:-0.477425436985;FOXP3:-0.480293023094;IRF1,2:-0.497234541142;BPTF:-0.51854499828;EVI1:-0.524643733645;SPIB:-0.532988890978;REST:-0.537992442169;ZFP161:-0.538681650538;EBF1:-0.549173252988;HIC1:-0.553840003838;GTF2I:-0.592896027457;POU6F1:-0.598633978513;TFAP2{A,C}:-0.600091991239;ZNF384:-0.602674728103;SPI1:-0.607914945987;POU2F1..3:-0.618322410853;RBPJ:-0.623423343977;NKX2-1,4:-0.628351551876;SOX5:-0.629245244715;AIRE:-0.636389888401;SRF:-0.644525280826;RUNX1..3:-0.714574963597;AR:-0.733633911191;TFAP4:-0.749329310444;FOXL1:-0.766126064617;FOXP1:-0.766505046527;ETS1,2:-0.778404935305;ADNP_IRX_SIX_ZHX:-0.788683521583;TFAP2B:-0.800013143371;TAL1_TCF{3,4,12}:-0.817946110633;HBP1_HMGB_SSRP1_UBTF:-0.827578125879;NHLH1,2:-0.830999368108;SP1:-0.838981653975;ZIC1..3:-0.839492205281;NFATC1..3:-0.857323076363;ATF2:-0.873550525048;MED-1{core}:-0.876171177111;HMGA1,2:-0.895567831727;GATA4:-0.901231281242;POU5F1:-0.952923916914;FOX{D1,D2}:-0.998328630513;SOX2:-1.0048757321;DMAP1_NCOR{1,2}_SMARC:-1.01193891764;RREB1:-1.03186458498;MYFfamily:-1.03526332826;TGIF1:-1.07054829679;MAZ:-1.0757838636;ZNF238:-1.12023944195;XCPE1{core}:-1.12617481611;EGR1..3:-1.14081430107;FOXO1,3,4:-1.14224191136;SMAD1..7,9:-1.15090251932;MTE{core}:-1.16996079383;XBP1:-1.170358838;NKX2-3_NKX2-5:-1.18711068592;TOPORS:-1.19851168107;PRDM1:-1.20146455297;STAT1,3:-1.34962664711;HMX1:-1.35552506957;MZF1:-1.36819348115;TLX2:-1.39672016351;NFIX:-1.40924611381;PATZ1:-1.42485524419;NANOG{mouse}:-1.45782202847;SPZ1:-1.83550848291 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11896-125E6;search_select_hide=table117:FF:11896-125E6 | |||
}} | }} |
Latest revision as of 18:27, 4 June 2020
Name: | Hep-2 cells treated with Streptococci strain JRS4, biol_rep3 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13499 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13499
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13499
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0294 |
10 | 10 | 0.0469 |
100 | 100 | 0.0409 |
101 | 101 | 0.276 |
102 | 102 | 0.911 |
103 | 103 | 0.493 |
104 | 104 | 0.851 |
105 | 105 | 0.174 |
106 | 106 | 0.0967 |
107 | 107 | 0.184 |
108 | 108 | 0.783 |
109 | 109 | 0.00111 |
11 | 11 | 0.468 |
110 | 110 | 0.228 |
111 | 111 | 0.272 |
112 | 112 | 0.779 |
113 | 113 | 0.00478 |
114 | 114 | 0.187 |
115 | 115 | 0.524 |
116 | 116 | 0.218 |
117 | 117 | 0.11 |
118 | 118 | 0.0822 |
119 | 119 | 0.255 |
12 | 12 | 0.477 |
120 | 120 | 0.0145 |
121 | 121 | 0.352 |
122 | 122 | 0.152 |
123 | 123 | 0.063 |
124 | 124 | 0.771 |
125 | 125 | 0.505 |
126 | 126 | 0.564 |
127 | 127 | 0.101 |
128 | 128 | 0.00115 |
129 | 129 | 0.693 |
13 | 13 | 2.64397e-4 |
130 | 130 | 0.765 |
131 | 131 | 0.175 |
132 | 132 | 0.95 |
133 | 133 | 0.119 |
134 | 134 | 0.878 |
135 | 135 | 0.316 |
136 | 136 | 0.00925 |
137 | 137 | 0.292 |
138 | 138 | 0.605 |
139 | 139 | 0.263 |
14 | 14 | 0.34 |
140 | 140 | 0.596 |
141 | 141 | 0.0561 |
142 | 142 | 0.868 |
143 | 143 | 0.615 |
144 | 144 | 0.571 |
145 | 145 | 0.24 |
146 | 146 | 0.996 |
147 | 147 | 0.579 |
148 | 148 | 0.392 |
149 | 149 | 0.678 |
15 | 15 | 0.255 |
150 | 150 | 0.466 |
151 | 151 | 0.863 |
152 | 152 | 0.662 |
153 | 153 | 0.517 |
154 | 154 | 0.285 |
155 | 155 | 0.183 |
156 | 156 | 0.0145 |
157 | 157 | 0.116 |
158 | 158 | 0.356 |
159 | 159 | 0.277 |
16 | 16 | 0.503 |
160 | 160 | 0.337 |
161 | 161 | 0.228 |
162 | 162 | 0.886 |
163 | 163 | 0.32 |
164 | 164 | 0.0205 |
165 | 165 | 0.9 |
166 | 166 | 0.0181 |
167 | 167 | 0.111 |
168 | 168 | 0.704 |
169 | 169 | 0.143 |
17 | 17 | 0.789 |
18 | 18 | 0.54 |
19 | 19 | 0.794 |
2 | 2 | 0.612 |
20 | 20 | 0.0942 |
21 | 21 | 0.13 |
22 | 22 | 0.928 |
23 | 23 | 0.0142 |
24 | 24 | 0.233 |
25 | 25 | 0.219 |
26 | 26 | 0.41 |
27 | 27 | 0.87 |
28 | 28 | 0.912 |
29 | 29 | 0.0066 |
3 | 3 | 0.879 |
30 | 30 | 0.394 |
31 | 31 | 0.696 |
32 | 32 | 0.187 |
33 | 33 | 0.141 |
34 | 34 | 0.267 |
35 | 35 | 0.789 |
36 | 36 | 0.0479 |
37 | 37 | 0.223 |
38 | 38 | 0.571 |
39 | 39 | 0.833 |
4 | 4 | 0.239 |
40 | 40 | 0.00591 |
41 | 41 | 0.346 |
42 | 42 | 0.765 |
43 | 43 | 0.896 |
44 | 44 | 0.0348 |
45 | 45 | 0.301 |
46 | 46 | 0.908 |
47 | 47 | 0.158 |
48 | 48 | 0.388 |
49 | 49 | 0.499 |
5 | 5 | 0.584 |
50 | 50 | 0.932 |
51 | 51 | 0.869 |
52 | 52 | 0.342 |
53 | 53 | 0.217 |
54 | 54 | 0.607 |
55 | 55 | 0.0609 |
56 | 56 | 0.788 |
57 | 57 | 0.286 |
58 | 58 | 0.703 |
59 | 59 | 0.82 |
6 | 6 | 0.877 |
60 | 60 | 0.879 |
61 | 61 | 0.0294 |
62 | 62 | 0.59 |
63 | 63 | 0.42 |
64 | 64 | 0.692 |
65 | 65 | 0.761 |
66 | 66 | 0.843 |
67 | 67 | 0.734 |
68 | 68 | 0.597 |
69 | 69 | 0.885 |
7 | 7 | 0.0194 |
70 | 70 | 0.851 |
71 | 71 | 0.00993 |
72 | 72 | 0.841 |
73 | 73 | 0.352 |
74 | 74 | 0.249 |
75 | 75 | 0.0986 |
76 | 76 | 0.175 |
77 | 77 | 0.294 |
78 | 78 | 0.1 |
79 | 79 | 0.937 |
8 | 8 | 0.0313 |
80 | 80 | 0.0559 |
81 | 81 | 0.522 |
82 | 82 | 0.301 |
83 | 83 | 0.439 |
84 | 84 | 0.352 |
85 | 85 | 0.0874 |
86 | 86 | 0.921 |
87 | 87 | 0.0068 |
88 | 88 | 0.989 |
89 | 89 | 0.513 |
9 | 9 | 0.72 |
90 | 90 | 0.0278 |
91 | 91 | 0.0082 |
92 | 92 | 0.37 |
93 | 93 | 0.207 |
94 | 94 | 0.805 |
95 | 95 | 0.011 |
96 | 96 | 0.593 |
97 | 97 | 0.888 |
98 | 98 | 0.712 |
99 | 99 | 0.705 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13499
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0011134 human Hep-2 cells treated with Streptococci strain JRS4 sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000066 (epithelial cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
162 (cancer)
14566 (disease of cellular proliferation)
0050687 (cell type cancer)
305 (carcinoma)
UBERON: Anatomy
0000468 (multi-cellular organism)
0001737 (larynx)
0000064 (organ part)
0004119 (endoderm-derived structure)
0000062 (organ)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000063 (organ segment)
0000477 (anatomical cluster)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0000072 (segment of respiratory tract)
0010317 (germ layer / neural crest derived structure)
0000065 (respiratory tract)
0001004 (respiratory system)
0001557 (upper respiratory tract)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0000625 (experimental infection sample)
0000350 (experimentally modified sample)
0000632 (group A streptococci treatment sample)
0104978 (HEp-2 cell sample)
0000639 (Streptococcus strain JRS4 treatment sample)
0100297 (carcinoma cell line sample)
0101120 (epithelial cell line sample)
0011134 (human Hep-2 cells treated with Streptococci strain JRS4 sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
UBERON:0008947 (respiratory primordium)
UBERON:0002532 (epiblast (generic))
UBERON:0006595 (presumptive endoderm)
UBERON:0010316 (germ layer / neural crest)