FF:13097-140D1: Difference between revisions
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{{f5samples | {{f5samples | ||
|ancestors_in_anatomy_facet=UBERON: | |DRA_sample_Accession=CAGE@SAMD00005523 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |DRA_sample_Accession_RNASeq=sRNA-Seq@SAMD00005523 | ||
|ancestors_in_disease_facet=DOID:0050686,DOID: | |accession_numbers=CAGE;DRX008592;DRR009464;DRZ000889;DRZ002274;DRZ012239;DRZ013624 | ||
|accession_numbers_RNASeq=sRNA-Seq;DRX037287;DRR041653;DRZ007295 | |||
|ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0000310,UBERON:0002100,UBERON:0000475,UBERON:0000061,UBERON:0000465,UBERON:0001062,UBERON:0009569,UBERON:0001443,UBERON:0000915 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0000066,CL:0000255 | |||
|ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:14566,DOID:0050687,DOID:7,DOID:5093,DOID:305,DOID:299,DOID:1612 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0000350,FF:0000344,FF:0000330,FF:0100093,FF:0100297,FF:0101912,FF:0101120,FF:0100816,FF:0100167,FF:0100356,FF:0000426 | |||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
|donor=biol_rep2 | |||
|expression_enrichment_score=chr10:8096631..8096660,+!p1@GATA3!2.81!768.08!GATA3;;chr14:38064429..38064486,-!p1@FOXA1!2.62!420.39!FOXA1;;chr6:34524093..34524135,-!p1@SPDEF!2.34!215.73!SPDEF;;chr20:55204351..55204377,+!p1@TFAP2C!2.15!177.01!TFAP2C;;chr1:201979743..201979762,+!p1@ELF3!1.92!81.39!ELF3;;chr10:8096772..8096787,+!p2@GATA3!1.84!80.60!GATA3;;chr22:29196433..29196445,-!p4@XBP1!1.74!59.27!XBP1;;chr17:59477233..59477263,+!p1@TBX2!1.70!146.98!TBX2;;chr8:102504651..102504683,+!p1@GRHL2!1.70!48.99!GRHL2;;chr5:2751762..2751784,-!p1@IRX2!1.68!47.41!IRX2;;chr10:8097321..8097348,+!p4@GATA3!1.68!46.62!GATA3;;chr10:8095593..8095625,+!p3@GATA3!1.63!48.20!GATA3;;chr17:59477197..59477212,+!p2@TBX2!1.56!60.06!TBX2;;chr22:29196492..29196503,-!p3@XBP1!1.53!49.78!XBP1;;chr6:152128810..152128827,+!p2@ESR1!1.52!32.40!ESR1;;chr15:96869511..96869525,+!p16@NR2F2!1.50!33.98!NR2F2;;chr8:99956662..99956684,+!p1@OSR2!1.49!45.04!OSR2;;chr6:126070769..126070801,+!p1@HEY2!1.43!30.03!HEY2;;chr14:37131058..37131139,+!p1@PAX9!1.41!24.50!PAX9;;chr9:129376201..129376225,+!p1@LMX1B!1.41!24.50!LMX1B;;chr10:8100691..8100732,+!p5@GATA3!1.38!22.92!GATA3;;chr22:29196547..29196563,-!p2@XBP1!1.37!794.16!XBP1;;chr12:53625966..53626012,-!p2@RARG!1.34!53.73!RARG;;chr20:50159198..50159299,-!p1@NFATC2!1.28!26.08!NFATC2;;chr11:65554528..65554546,+!p1@OVOL1!1.28!18.17!OVOL1;;chr16:29818199..29818216,+!p11@MAZ!1.26!27.66!MAZ;;chr14:38064307..38064323,-!p3@FOXA1!1.26!17.38!FOXA1;;chr3:147111198..147111225,+!p4@ZIC1!1.26!17.38!ZIC1;;chr9:129376233..129376251,+!p2@LMX1B!1.26!17.38!LMX1B;;chr14:38064590..38064606,-!p2@FOXA1!1.25!16.59!FOXA1;;chr19:45579725..45579743,-!p1@ZNF296!1.24!71.91!ZNF296;;chr14:75988771..75988826,+!p1@BATF!1.23!21.34!BATF;;chr6:135502501..135502546,+!p1@MYB!1.23!18.96!MYB;;chr7:156803329..156803362,-!p1@MNX1!1.23!15.80!MNX1;;chr8:102504979..102505010,+!p2@GRHL2!1.18!14.22!GRHL2;;chr10:8097295..8097320,+!p6@GATA3!1.18!14.22!GATA3;;chr20:46130619..46130664,+!p1@NCOA3!1.17!365.07!NCOA3;;chr14:105267423..105267443,+!p2@ZBTB42!1.16!13.43!ZBTB42;;chr5:2751785..2751808,-!p2@IRX2!1.16!13.43!IRX2;;chr8:102504690..102504704,+!p3@GRHL2!1.16!13.43!GRHL2;;chr5:174151553..174151610,+!p1@MSX2!1.14!21.34!MSX2;;chr10:135122906..135122921,+!p4@ZNF511!1.13!12.64!ZNF511;;chr11:65554563..65554576,+!p2@OVOL1!1.13!12.64!OVOL1;;chr14:38064495..38064506,-!p4@FOXA1!1.13!12.64!FOXA1;;chrX:2418949..2419024,-!p1@DHRSX,p1@ZBED1!1.13!12.64!ZBED1;;chr17:59477403..59477414,+!p4@TBX2!1.13!12.64!TBX2;;chr18:3449330..3449344,+!p10@TGIF1!1.11!15.80!TGIF1;;chr3:128206762..128206781,-!p2@GATA2!1.10!71.91!GATA2;;chr20:42295745..42295765,+!p1@MYBL2!1.09!186.49!MYBL2;;chr17:61920023..61920110,-!p1@SMARCD2!1.08!155.67!SMARCD2;;chr16:29818160..29818188,+!p6@MAZ!1.08!51.36!MAZ;;chr14:38065203..38065215,-!p9@FOXA1!1.08!11.06!FOXA1;;chr1:201979703..201979721,+!p2@ELF3!1.08!11.06!ELF3;;chr1:149858461..149858479,+!p1@BOLA1!1.05!3977.89!BOLA1;;chr20:52210553..52210568,-!p7@ZNF217!1.05!10.27!ZNF217;;chr11:129245526..129245553,+!p1@BARX2!1.05!10.27!BARX2;;chr17:59477275..59477286,+!p3@TBX2!1.04!13.43!TBX2;;chr16:54964740..54964789,+!p1@IRX5!1.03!14.22!IRX5;;chr10:48355030..48355090,+!p1@ZNF488!1.03!12.64!ZNF488;;chr1:935398..935465,-!p2@HES4!1.02!19.76!HES4;;chr17:17726907..17726958,-!p2@SREBF1!1.01!58.48!SREBF1;;chr17:61919985..61920012,-!p3@SMARCD2!1.00!22.13!SMARCD2;;chr1:209979467..209979494,-!p1@IRF6!1.00!10.27!IRF6;;chr14:95236440..95236465,-!p1@GSC!0.99!8.69!GSC;;chr6:135502472..135502489,+!p3@MYB!0.99!8.69!MYB;;chr12:54332608..54332636,+!p1@HOXC13!0.99!8.69!HOXC13;;chr22:29196030..29196075,-!p5@XBP1!0.98!11.06!XBP1;;chr7:149470641..149470694,-!p1@ZNF467!0.97!38.72!ZNF467;;chr19:33793430..33793447,-!p1@CEBPA!0.97!36.35!CEBPA;;chr5:174151612..174151633,+!p2@MSX2!0.95!7.90!MSX2;;chr6:152128782..152128803,+!p5@ESR1!0.95!7.90!ESR1;;chr6:34524049..34524089,-!p2@SPDEF!0.95!7.90!SPDEF;;chr3:147111231..147111281,+!p3@ZIC1!0.95!7.90!ZIC1;;chr17:7388010..7388017,-!p5@ZBTB4!0.94!13.43!ZBTB4;;chr8:37553292..37553317,+!p1@ZNF703!0.93!186.49!ZNF703;;chr5:176738887..176738934,-!p1@MXD3!0.93!52.15!MXD3;;chr1:23857698..23857733,-!p1@E2F2!0.93!14.22!E2F2;;chr2:239148671..239148686,-!p1@HES6!0.92!27.66!HES6;;chr8:116681409..116681431,-!p2@TRPS1!0.92!20.55!TRPS1;;chr12:80084737..80084763,-!p3@PAWR!0.91!27.66!PAWR;;chr16:54964899..54964914,+!p2@IRX5!0.91!7.11!IRX5;;chr17:48045917..48045977,+!p1@DLX4!0.91!7.11!DLX4;;chr17:7197911..7197964,-!p1@YBX2!0.91!7.11!YBX2;;chr6:20402102..20402152,+!p1@E2F3!0.90!30.03!E2F3;;chr2:157199008..157199023,-!p3@NR4A2!0.90!15.01!NR4A2;;chr1:41827095..41827155,+!p1@FOXO6!0.90!9.48!FOXO6;;chr20:46130602..46130613,+!p3@NCOA3!0.89!20.55!NCOA3;;chr1:149871171..149871192,+!p4@BOLA1!0.89!15.80!BOLA1;;chr15:67418047..67418093,+!p4@SMAD3!0.89!8.69!SMAD3;;chr14:69262789..69262822,-!p2@ZFP36L1!0.87!17.38!ZFP36L1;;chr20:52210338..52210352,-!p4@ZNF217!0.87!7.90!ZNF217;;chr15:67418119..67418162,+!p5@SMAD3!0.87!7.11!SMAD3;;chr1:154975258..154975330,+!p1@ZBTB7B!0.86!24.50!ZBTB7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| |||
|fonse_cell_line=FF:0100816,FF:0101120 | |fonse_cell_line=FF:0100816,FF:0101120 | ||
|fonse_cell_line_closure=FF:0100816,FF:0101120 | |fonse_cell_line_closure=FF:0100816,FF:0101120 | ||
Line 34: | Line 43: | ||
|fonse_treatment_closure=EFO:0000369,FF:0000330,FF:0000426,FF:13097-140D1 | |fonse_treatment_closure=EFO:0000369,FF:0000330,FF:0000426,FF:13097-140D1 | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.timecourse.hCAGE/MCF7%2520breast%2520cancer%2520cell%2520line%2520response%2520to%2520EGF1%252c%252000hr00min%252c%2520biol_rep2.CNhs12475.13097-140D1.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.timecourse.hCAGE/MCF7%2520breast%2520cancer%2520cell%2520line%2520response%2520to%2520EGF1%252c%252000hr00min%252c%2520biol_rep2.CNhs12475.13097-140D1.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.timecourse.hCAGE/MCF7%2520breast%2520cancer%2520cell%2520line%2520response%2520to%2520EGF1%252c%252000hr00min%252c%2520biol_rep2.CNhs12475.13097-140D1.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.timecourse.hCAGE/MCF7%2520breast%2520cancer%2520cell%2520line%2520response%2520to%2520EGF1%252c%252000hr00min%252c%2520biol_rep2.CNhs12475.13097-140D1.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.timecourse.hCAGE/MCF7%2520breast%2520cancer%2520cell%2520line%2520response%2520to%2520EGF1%252c%252000hr00min%252c%2520biol_rep2.CNhs12475.13097-140D1.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:13097-140D1 | |id=FF:13097-140D1 | ||
|is_a=EFO:0002091;;FF: | |is_a=EFO:0002091;;FF:0000426 | ||
|name=MCF7 breast cancer cell line response to EGF1 | |is_obsolete= | ||
|library_id=CNhs12475 | |||
|library_id_phase_based=2:CNhs12475 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;13097 | |||
|microRNAs_nonnovel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer/#/human#srna;sample;SRhi10063.ACTTGA.13097 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;13097 | |||
|microRNAs_novel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer_novel/#/human#srna;sample;SRhi10063.ACTTGA.13097 | |||
|name=MCF7 breast cancer cell line response to EGF1 | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |profile_cagescan=,,, | ||
|profile_hcage=CNhs12475,LSID916,release011,COMPLETED | |profile_hcage=CNhs12475,LSID916,release011,COMPLETED | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq=,,, | |profile_srnaseq=,,, | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,0.25137048353106,0,0.496426772812389,0.742459559533734,0,0,0,0,0,0,0,0,0,0,0,0.252902619716208,0,0.60568166193542,0,0,0,0,0,1.08456172641691,0,0,0.919069709564138,0,0,0,0,0,0,0,0,0,0,0,0,0.607562249353455,0.252902619716208,0,0,0,0,0,0,0,0.102236288745269,0,0,0,0,0,0,0,0.923470553297723,0,0,0.31434488640435,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.361585539475162,0,0,0,0.0216039058765901,-0.211197402695869,0,0,0,0,-0.0980353512377064,0.125377257422946,0,0,0,0,0,0,0.411688513617447,0,0,0,0,0,0,0,0,0,0,-0.096373593922461,0.252902619716208,0,0,0.438847450271258,0.543634124468516,0,0,0.337000165040999,0,0,0 | |||
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| |||
|rna_box=140 | |rna_box=140 | ||
|rna_catalog_number= | |rna_catalog_number= | ||
|rna_concentration=0. | |rna_concentration=0.8 | ||
|rna_extraction_protocol=Repurified by minelute | |rna_extraction_protocol=Repurified by minelute | ||
|rna_lot_number= | |rna_lot_number= | ||
Line 55: | Line 81: | ||
|rna_tube_id=140D1 | |rna_tube_id=140D1 | ||
|rna_weight_ug=8.04 | |rna_weight_ug=8.04 | ||
|rnaseq_library_id=SRhi10063.ACTTGA | |||
|sample_age= | |sample_age= | ||
|sample_category=time courses | |||
|sample_cell_catalog= | |sample_cell_catalog= | ||
|sample_cell_line=MCF7 | |sample_cell_line=MCF7 | ||
Line 68: | Line 96: | ||
|sample_ethnicity= | |sample_ethnicity= | ||
|sample_experimental_condition=MCF7 breast cancer cell line response to Epidermal Growth Factor 1 | |sample_experimental_condition=MCF7 breast cancer cell line response to Epidermal Growth Factor 1 | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;2.30083107488843e-246!GO:0043231;intracellular membrane-bound organelle;4.90456521987727e-216!GO:0043227;membrane-bound organelle;6.69087174518561e-216!GO:0043226;organelle;2.25591281081836e-209!GO:0043229;intracellular organelle;7.5537677979384e-209!GO:0005737;cytoplasm;3.96384299334575e-169!GO:0044422;organelle part;7.15085496827804e-150!GO:0044446;intracellular organelle part;1.43461364696114e-148!GO:0044444;cytoplasmic part;4.49164526264422e-128!GO:0044237;cellular metabolic process;4.73319499840646e-96!GO:0032991;macromolecular complex;7.75227581039111e-95!GO:0005634;nucleus;2.0666041487065e-92!GO:0044238;primary metabolic process;3.87960076607563e-92!GO:0043170;macromolecule metabolic process;2.13137838604793e-83!GO:0030529;ribonucleoprotein complex;2.62635961728237e-80!GO:0005739;mitochondrion;1.85279168236981e-76!GO:0044428;nuclear part;4.88731936043528e-75!GO:0043233;organelle lumen;1.22735261781513e-72!GO:0031974;membrane-enclosed lumen;1.22735261781513e-72!GO:0003723;RNA binding;4.26251776713358e-65!GO:0005515;protein binding;4.50697601669318e-63!GO:0005840;ribosome;5.43296058274962e-53!GO:0031090;organelle membrane;9.6946479555182e-53!GO:0043283;biopolymer metabolic process;3.68184446993747e-52!GO:0044429;mitochondrial part;9.84407094638603e-49!GO:0043234;protein complex;1.74209087352423e-48!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;4.11673545915938e-48!GO:0006412;translation;5.15000700291083e-47!GO:0031981;nuclear lumen;1.5796416148688e-46!GO:0003735;structural constituent of ribosome;1.90866241972306e-46!GO:0006396;RNA processing;3.44445587363216e-46!GO:0031967;organelle envelope;4.03531449366355e-44!GO:0010467;gene expression;8.66649664653717e-44!GO:0031975;envelope;9.68350687213199e-44!GO:0015031;protein transport;2.01147502399066e-42!GO:0019538;protein metabolic process;3.66850374342949e-42!GO:0033036;macromolecule localization;1.96033051409115e-41!GO:0033279;ribosomal subunit;1.94410156538154e-40!GO:0016043;cellular component organization and biogenesis;1.08993788336055e-38!GO:0044249;cellular biosynthetic process;1.39192623929618e-38!GO:0009058;biosynthetic process;1.58232261953152e-38!GO:0006259;DNA metabolic process;1.79412120320091e-38!GO:0008104;protein localization;2.38104494372245e-38!GO:0044260;cellular macromolecule metabolic process;3.5037350878363e-38!GO:0044267;cellular protein metabolic process;6.82814395657897e-38!GO:0045184;establishment of protein localization;1.7512989752402e-37!GO:0005829;cytosol;7.56688408285584e-36!GO:0009059;macromolecule biosynthetic process;8.67243472240282e-36!GO:0016071;mRNA metabolic process;8.84020552975222e-36!GO:0065003;macromolecular complex assembly;1.57720071856697e-32!GO:0043228;non-membrane-bound organelle;3.12302980088591e-32!GO:0043232;intracellular non-membrane-bound organelle;3.12302980088591e-32!GO:0005740;mitochondrial envelope;5.07467346319385e-32!GO:0019866;organelle inner membrane;1.2415315594374e-31!GO:0006397;mRNA processing;2.36993092631933e-31!GO:0008380;RNA splicing;6.70379369649497e-31!GO:0031966;mitochondrial membrane;1.62395399880689e-30!GO:0046907;intracellular transport;1.33753157809527e-29!GO:0006996;organelle organization and biogenesis;1.34519582424671e-29!GO:0005743;mitochondrial inner membrane;1.92270092153151e-29!GO:0005654;nucleoplasm;2.52681166218832e-29!GO:0022607;cellular component assembly;3.66850335419988e-28!GO:0005830;cytosolic ribosome (sensu Eukaryota);9.94950540242579e-28!GO:0006886;intracellular protein transport;1.38980219211706e-26!GO:0007049;cell cycle;3.15001434386485e-26!GO:0003676;nucleic acid binding;1.33856117840194e-25!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.37072225326359e-25!GO:0044451;nucleoplasm part;3.6868926611542e-24!GO:0000166;nucleotide binding;2.69740884708003e-23!GO:0044445;cytosolic part;4.82193781001616e-23!GO:0006119;oxidative phosphorylation;8.48058314259542e-23!GO:0005681;spliceosome;9.7945682625991e-23!GO:0015934;large ribosomal subunit;2.81758894147213e-21!GO:0016874;ligase activity;3.4933485420404e-21!GO:0031980;mitochondrial lumen;6.74059137802359e-21!GO:0005759;mitochondrial matrix;6.74059137802359e-21!GO:0012505;endomembrane system;1.33701351782746e-20!GO:0016070;RNA metabolic process;1.91108624169832e-20!GO:0015935;small ribosomal subunit;2.91688175228073e-20!GO:0022402;cell cycle process;2.94217436082886e-20!GO:0006974;response to DNA damage stimulus;5.74391655973005e-20!GO:0044455;mitochondrial membrane part;9.57741520491307e-20!GO:0006512;ubiquitin cycle;1.50489470187884e-19!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.75690990318232e-19!GO:0051649;establishment of cellular localization;2.0667661745283e-19!GO:0016462;pyrophosphatase activity;2.38963561786261e-19!GO:0016817;hydrolase activity, acting on acid anhydrides;2.57618154732337e-19!GO:0017111;nucleoside-triphosphatase activity;1.0364940977731e-18!GO:0051641;cellular localization;1.04271632912141e-18!GO:0005694;chromosome;3.91212295386766e-18!GO:0051186;cofactor metabolic process;1.60954098841276e-17!GO:0051276;chromosome organization and biogenesis;1.63448603182088e-17!GO:0005730;nucleolus;2.03947172252678e-17!GO:0006281;DNA repair;2.97199085111296e-17!GO:0032553;ribonucleotide binding;4.47063588496869e-17!GO:0032555;purine ribonucleotide binding;4.47063588496869e-17!GO:0044265;cellular macromolecule catabolic process;6.31427519279645e-17!GO:0006325;establishment and/or maintenance of chromatin architecture;8.68125812006619e-17!GO:0000278;mitotic cell cycle;8.87299884266019e-17!GO:0044427;chromosomal part;1.02180694600933e-16!GO:0005524;ATP binding;2.04437408509327e-16!GO:0032559;adenyl ribonucleotide binding;3.4468480673486e-16!GO:0017076;purine nucleotide binding;4.51840619066035e-16!GO:0006323;DNA packaging;5.71666150356956e-16!GO:0005746;mitochondrial respiratory chain;6.17800279727803e-16!GO:0009719;response to endogenous stimulus;9.2963402683473e-16!GO:0000502;proteasome complex (sensu Eukaryota);9.49543847872244e-16!GO:0005761;mitochondrial ribosome;1.87222185748496e-15!GO:0000313;organellar ribosome;1.87222185748496e-15!GO:0006457;protein folding;2.07830490344975e-15!GO:0051603;proteolysis involved in cellular protein catabolic process;2.85846435286212e-15!GO:0043285;biopolymer catabolic process;3.269846905161e-15!GO:0008134;transcription factor binding;3.60773822308394e-15!GO:0019941;modification-dependent protein catabolic process;3.60773822308394e-15!GO:0043632;modification-dependent macromolecule catabolic process;3.60773822308394e-15!GO:0044257;cellular protein catabolic process;4.93499592610466e-15!GO:0030554;adenyl nucleotide binding;6.15392580313115e-15!GO:0006511;ubiquitin-dependent protein catabolic process;8.49877382966316e-15!GO:0044432;endoplasmic reticulum part;9.56780531897125e-15!GO:0048770;pigment granule;9.58566905025532e-15!GO:0042470;melanosome;9.58566905025532e-15!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.04951397175266e-14!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.14415604197805e-14!GO:0044248;cellular catabolic process;1.3790177542619e-14!GO:0022618;protein-RNA complex assembly;2.00954675982477e-14!GO:0005783;endoplasmic reticulum;2.38320749962608e-14!GO:0050136;NADH dehydrogenase (quinone) activity;2.75049937296731e-14!GO:0003954;NADH dehydrogenase activity;2.75049937296731e-14!GO:0008137;NADH dehydrogenase (ubiquinone) activity;2.75049937296731e-14!GO:0009057;macromolecule catabolic process;3.34705709672694e-14!GO:0006732;coenzyme metabolic process;4.51497434104381e-14!GO:0006260;DNA replication;1.00616282461307e-13!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.0185761314603e-13!GO:0043412;biopolymer modification;1.20929616373425e-13!GO:0008135;translation factor activity, nucleic acid binding;1.82587325604335e-13!GO:0006333;chromatin assembly or disassembly;1.8808400104427e-13!GO:0031965;nuclear membrane;2.54768730988415e-13!GO:0042623;ATPase activity, coupled;2.75589592906818e-13!GO:0016887;ATPase activity;2.92079468629969e-13!GO:0000087;M phase of mitotic cell cycle;3.67885436365687e-13!GO:0051301;cell division;4.61405842687792e-13!GO:0005635;nuclear envelope;4.73339234187531e-13!GO:0000398;nuclear mRNA splicing, via spliceosome;4.83403004819943e-13!GO:0000375;RNA splicing, via transesterification reactions;4.83403004819943e-13!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;4.83403004819943e-13!GO:0007067;mitosis;4.87934917039281e-13!GO:0022403;cell cycle phase;6.0275837787179e-13!GO:0006605;protein targeting;7.6974584023723e-13!GO:0042775;organelle ATP synthesis coupled electron transport;1.18073685785501e-12!GO:0042773;ATP synthesis coupled electron transport;1.18073685785501e-12!GO:0051082;unfolded protein binding;1.35070258068476e-12!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.83121264809356e-12!GO:0065004;protein-DNA complex assembly;2.49356116663658e-12!GO:0030163;protein catabolic process;2.60903639114585e-12!GO:0030964;NADH dehydrogenase complex (quinone);3.29685921267479e-12!GO:0045271;respiratory chain complex I;3.29685921267479e-12!GO:0005747;mitochondrial respiratory chain complex I;3.29685921267479e-12!GO:0042175;nuclear envelope-endoplasmic reticulum network;4.8084468150487e-12!GO:0051726;regulation of cell cycle;6.43814464769808e-12!GO:0005789;endoplasmic reticulum membrane;7.80776250971498e-12!GO:0000785;chromatin;9.45529830428954e-12!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.11778325337984e-11!GO:0006464;protein modification process;1.32205501548744e-11!GO:0042254;ribosome biogenesis and assembly;1.55919345172796e-11!GO:0000074;regulation of progression through cell cycle;1.77768786164721e-11!GO:0044453;nuclear membrane part;2.95203637946591e-11!GO:0005794;Golgi apparatus;3.16247996311807e-11!GO:0000279;M phase;3.61892142385746e-11!GO:0051188;cofactor biosynthetic process;3.66071343446146e-11!GO:0016879;ligase activity, forming carbon-nitrogen bonds;4.028014872652e-11!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;4.2130028236478e-11!GO:0006913;nucleocytoplasmic transport;4.46146440323832e-11!GO:0016604;nuclear body;9.30151900558097e-11!GO:0051169;nuclear transport;1.18592145610806e-10!GO:0006399;tRNA metabolic process;1.27204001268198e-10!GO:0048193;Golgi vesicle transport;1.43716396014906e-10!GO:0008639;small protein conjugating enzyme activity;1.99727230157273e-10!GO:0043687;post-translational protein modification;2.83965515298204e-10!GO:0019787;small conjugating protein ligase activity;3.86586816956402e-10!GO:0006334;nucleosome assembly;4.56822743196822e-10!GO:0004842;ubiquitin-protein ligase activity;5.24601710676775e-10!GO:0006366;transcription from RNA polymerase II promoter;6.950906628836e-10!GO:0031497;chromatin assembly;7.51890423353652e-10!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;8.07501975015222e-10!GO:0006163;purine nucleotide metabolic process;8.79014330528715e-10!GO:0009259;ribonucleotide metabolic process;9.4335019989585e-10!GO:0016568;chromatin modification;1.0012008051801e-09!GO:0019829;cation-transporting ATPase activity;1.0680319631672e-09!GO:0003712;transcription cofactor activity;1.13131193801071e-09!GO:0005643;nuclear pore;1.91618942934865e-09!GO:0015986;ATP synthesis coupled proton transport;2.10026528353604e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;2.10026528353604e-09!GO:0004386;helicase activity;2.34367655647974e-09!GO:0016192;vesicle-mediated transport;2.53870687244092e-09!GO:0009108;coenzyme biosynthetic process;2.72226094653117e-09!GO:0003743;translation initiation factor activity;2.87927299889759e-09!GO:0009199;ribonucleoside triphosphate metabolic process;4.14111176091317e-09!GO:0006164;purine nucleotide biosynthetic process;4.32376133600729e-09!GO:0008026;ATP-dependent helicase activity;4.32376133600729e-09!GO:0009150;purine ribonucleotide metabolic process;4.9660424219517e-09!GO:0015078;hydrogen ion transmembrane transporter activity;5.40160752619865e-09!GO:0009141;nucleoside triphosphate metabolic process;5.66302452932805e-09!GO:0009205;purine ribonucleoside triphosphate metabolic process;6.12975419259966e-09!GO:0009144;purine nucleoside triphosphate metabolic process;6.12975419259966e-09!GO:0009142;nucleoside triphosphate biosynthetic process;6.62721554344648e-09!GO:0009201;ribonucleoside triphosphate biosynthetic process;6.62721554344648e-09!GO:0009260;ribonucleotide biosynthetic process;7.57523835785083e-09!GO:0016881;acid-amino acid ligase activity;8.00079638444845e-09!GO:0006461;protein complex assembly;9.29651541968446e-09!GO:0006446;regulation of translational initiation;9.5165813730105e-09!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;9.92884877322753e-09!GO:0009145;purine nucleoside triphosphate biosynthetic process;9.92884877322753e-09!GO:0008565;protein transporter activity;1.0508788339146e-08!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.05351622910656e-08!GO:0017038;protein import;1.49839000995509e-08!GO:0012501;programmed cell death;1.50269966391752e-08!GO:0006413;translational initiation;1.65571581396042e-08!GO:0050657;nucleic acid transport;1.76927995057665e-08!GO:0051236;establishment of RNA localization;1.76927995057665e-08!GO:0050658;RNA transport;1.76927995057665e-08!GO:0046034;ATP metabolic process;2.09685467171428e-08!GO:0065002;intracellular protein transport across a membrane;2.32305896880762e-08!GO:0009152;purine ribonucleotide biosynthetic process;2.39457623258899e-08!GO:0006754;ATP biosynthetic process;2.39457623258899e-08!GO:0006753;nucleoside phosphate metabolic process;2.39457623258899e-08!GO:0006403;RNA localization;2.46362936095015e-08!GO:0006915;apoptosis;2.50917638296045e-08!GO:0032446;protein modification by small protein conjugation;2.93837424862639e-08!GO:0016779;nucleotidyltransferase activity;3.47413667581602e-08!GO:0016740;transferase activity;3.8727251501016e-08!GO:0009056;catabolic process;4.40694666708382e-08!GO:0016567;protein ubiquitination;4.43310553710001e-08!GO:0046930;pore complex;5.06057506808623e-08!GO:0006364;rRNA processing;5.32276944279757e-08!GO:0005793;ER-Golgi intermediate compartment;5.34786636323268e-08!GO:0003697;single-stranded DNA binding;5.46939107457023e-08!GO:0016072;rRNA metabolic process;7.14886637536742e-08!GO:0009060;aerobic respiration;7.59605430915852e-08!GO:0005768;endosome;8.82981507044515e-08!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.04952474832883e-07!GO:0004812;aminoacyl-tRNA ligase activity;1.04952474832883e-07!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.04952474832883e-07!GO:0009117;nucleotide metabolic process;1.05471918757493e-07!GO:0007005;mitochondrion organization and biogenesis;1.1230132340019e-07!GO:0005667;transcription factor complex;1.14746631268045e-07!GO:0008219;cell death;1.51145319704177e-07!GO:0016265;death;1.51145319704177e-07!GO:0016469;proton-transporting two-sector ATPase complex;1.51930995294304e-07!GO:0006261;DNA-dependent DNA replication;2.19177913210253e-07!GO:0016607;nuclear speck;2.20222203372364e-07!GO:0009055;electron carrier activity;2.62819370452892e-07!GO:0043038;amino acid activation;2.96816345017988e-07!GO:0006418;tRNA aminoacylation for protein translation;2.96816345017988e-07!GO:0043039;tRNA aminoacylation;2.96816345017988e-07!GO:0030532;small nuclear ribonucleoprotein complex;3.08681430713298e-07!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;3.37944877061579e-07!GO:0006752;group transfer coenzyme metabolic process;3.44769802546406e-07!GO:0015077;monovalent inorganic cation transmembrane transporter activity;4.14033324280045e-07!GO:0016787;hydrolase activity;5.89511274166159e-07!GO:0016772;transferase activity, transferring phosphorus-containing groups;8.04498783999601e-07!GO:0045259;proton-transporting ATP synthase complex;1.04402262628656e-06!GO:0045333;cellular respiration;1.16856735638816e-06!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.20771287414268e-06!GO:0044431;Golgi apparatus part;1.25736328157229e-06!GO:0051028;mRNA transport;1.2694059050881e-06!GO:0016023;cytoplasmic membrane-bound vesicle;1.46548490266029e-06!GO:0043623;cellular protein complex assembly;1.76691142952461e-06!GO:0031988;membrane-bound vesicle;1.8337916431611e-06!GO:0043566;structure-specific DNA binding;2.17812203392283e-06!GO:0000245;spliceosome assembly;2.59764972674535e-06!GO:0042802;identical protein binding;3.56379344966778e-06!GO:0015630;microtubule cytoskeleton;3.60293782088733e-06!GO:0050794;regulation of cellular process;3.93379473514844e-06!GO:0000151;ubiquitin ligase complex;4.32525222035904e-06!GO:0005839;proteasome core complex (sensu Eukaryota);4.94868599428013e-06!GO:0000786;nucleosome;5.26931851281663e-06!GO:0005762;mitochondrial large ribosomal subunit;5.60854889823932e-06!GO:0000315;organellar large ribosomal subunit;5.60854889823932e-06!GO:0006099;tricarboxylic acid cycle;5.646119479238e-06!GO:0046356;acetyl-CoA catabolic process;5.646119479238e-06!GO:0006793;phosphorus metabolic process;6.8809693301759e-06!GO:0006796;phosphate metabolic process;6.8809693301759e-06!GO:0005819;spindle;8.00847313235935e-06!GO:0051427;hormone receptor binding;9.26260873252144e-06!GO:0016563;transcription activator activity;1.01638250900706e-05!GO:0016564;transcription repressor activity;1.04698372732099e-05!GO:0006084;acetyl-CoA metabolic process;1.15633326479591e-05!GO:0051170;nuclear import;1.16558347832987e-05!GO:0048475;coated membrane;1.2805204695554e-05!GO:0030117;membrane coat;1.2805204695554e-05!GO:0008654;phospholipid biosynthetic process;1.41451140160967e-05!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.57814285778576e-05!GO:0031982;vesicle;1.82987061838503e-05!GO:0004298;threonine endopeptidase activity;1.83623772648319e-05!GO:0031410;cytoplasmic vesicle;2.11114665220033e-05!GO:0030120;vesicle coat;2.11114665220033e-05!GO:0030662;coated vesicle membrane;2.11114665220033e-05!GO:0035257;nuclear hormone receptor binding;2.21318525453165e-05!GO:0000314;organellar small ribosomal subunit;2.3088066486786e-05!GO:0005763;mitochondrial small ribosomal subunit;2.3088066486786e-05!GO:0006606;protein import into nucleus;2.32543897255277e-05!GO:0003724;RNA helicase activity;2.65996073352064e-05!GO:0015992;proton transport;3.03952567095261e-05!GO:0051329;interphase of mitotic cell cycle;3.03952567095261e-05!GO:0003713;transcription coactivator activity;3.04521131651686e-05!GO:0031324;negative regulation of cellular metabolic process;3.33229360176667e-05!GO:0005773;vacuole;3.33517986026362e-05!GO:0051168;nuclear export;3.33882458524579e-05!GO:0006414;translational elongation;3.56182131660016e-05!GO:0006818;hydrogen transport;3.74598257204806e-05!GO:0051187;cofactor catabolic process;4.10030559184286e-05!GO:0016310;phosphorylation;4.62086698594801e-05!GO:0009165;nucleotide biosynthetic process;4.64331662168507e-05!GO:0045786;negative regulation of progression through cell cycle;5.16776528624396e-05!GO:0009109;coenzyme catabolic process;5.16776528624396e-05!GO:0019222;regulation of metabolic process;5.71236107879313e-05!GO:0006888;ER to Golgi vesicle-mediated transport;5.75531321496688e-05!GO:0044440;endosomal part;6.02838368290748e-05!GO:0010008;endosome membrane;6.02838368290748e-05!GO:0005657;replication fork;6.23125898158838e-05!GO:0008094;DNA-dependent ATPase activity;6.52943526728537e-05!GO:0003899;DNA-directed RNA polymerase activity;7.90888501456727e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;8.01005702177256e-05!GO:0005798;Golgi-associated vesicle;8.47474706447431e-05!GO:0051325;interphase;8.54781792699315e-05!GO:0043067;regulation of programmed cell death;8.68725290305069e-05!GO:0006357;regulation of transcription from RNA polymerase II promoter;9.26986011131226e-05!GO:0005813;centrosome;0.000100326973698501!GO:0007051;spindle organization and biogenesis;0.000106393801841194!GO:0042981;regulation of apoptosis;0.00010776264889138!GO:0000139;Golgi membrane;0.000109070480569105!GO:0016741;transferase activity, transferring one-carbon groups;0.000128051312585218!GO:0000775;chromosome, pericentric region;0.000141943121433453!GO:0008168;methyltransferase activity;0.000145492878272733!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000146916293216175!GO:0015399;primary active transmembrane transporter activity;0.000146916293216175!GO:0005770;late endosome;0.000149435844715894!GO:0048471;perinuclear region of cytoplasm;0.00015520452854741!GO:0008033;tRNA processing;0.000156237329571304!GO:0051246;regulation of protein metabolic process;0.000158998861052509!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00016434610078439!GO:0003714;transcription corepressor activity;0.000166778209842143!GO:0005815;microtubule organizing center;0.000192675961953173!GO:0009892;negative regulation of metabolic process;0.00019731029715245!GO:0000323;lytic vacuole;0.000205844203213767!GO:0005764;lysosome;0.000205844203213767!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000216372320226311!GO:0005769;early endosome;0.000221858554499572!GO:0000075;cell cycle checkpoint;0.000224174434972733!GO:0008186;RNA-dependent ATPase activity;0.000275002718681216!GO:0003684;damaged DNA binding;0.000282307808304273!GO:0046474;glycerophospholipid biosynthetic process;0.000291402405224637!GO:0003924;GTPase activity;0.000296446293370694!GO:0006401;RNA catabolic process;0.000300340515858669!GO:0003682;chromatin binding;0.000302381140538711!GO:0006613;cotranslational protein targeting to membrane;0.000316877892971478!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000316877892971478!GO:0006916;anti-apoptosis;0.000343527942378548!GO:0043069;negative regulation of programmed cell death;0.000348390108150644!GO:0048523;negative regulation of cellular process;0.000352792591741893!GO:0016491;oxidoreductase activity;0.000385853965037066!GO:0006091;generation of precursor metabolites and energy;0.000388517625732079!GO:0030867;rough endoplasmic reticulum membrane;0.000392069891769872!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000409308126799609!GO:0006402;mRNA catabolic process;0.000452443408343701!GO:0006839;mitochondrial transport;0.000452443408343701!GO:0043681;protein import into mitochondrion;0.00049371831958932!GO:0031252;leading edge;0.000500576242594094!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000521340039039913!GO:0046489;phosphoinositide biosynthetic process;0.000629063152158352!GO:0043284;biopolymer biosynthetic process;0.000647214718516936!GO:0033116;ER-Golgi intermediate compartment membrane;0.000701637431151234!GO:0016853;isomerase activity;0.000727947078799902!GO:0004004;ATP-dependent RNA helicase activity;0.000727947078799902!GO:0043066;negative regulation of apoptosis;0.000762001883632664!GO:0005048;signal sequence binding;0.000762001883632664!GO:0003729;mRNA binding;0.000766346952101605!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000786828393372755!GO:0043492;ATPase activity, coupled to movement of substances;0.000798817035840298!GO:0051789;response to protein stimulus;0.000847941820253067!GO:0006986;response to unfolded protein;0.000847941820253067!GO:0005788;endoplasmic reticulum lumen;0.000858047852245463!GO:0003746;translation elongation factor activity;0.000880838030274013!GO:0051087;chaperone binding;0.00092307504455897!GO:0046983;protein dimerization activity;0.000926514950537892!GO:0016363;nuclear matrix;0.000926514950537892!GO:0032508;DNA duplex unwinding;0.000950254400118729!GO:0032392;DNA geometric change;0.000950254400118729!GO:0051920;peroxiredoxin activity;0.000967838168725873!GO:0022890;inorganic cation transmembrane transporter activity;0.000976040274664388!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000979100551201262!GO:0004518;nuclease activity;0.000980021818218162!GO:0005684;U2-dependent spliceosome;0.000982404166125908!GO:0016481;negative regulation of transcription;0.00101509931358941!GO:0006284;base-excision repair;0.00101953571736306!GO:0016126;sterol biosynthetic process;0.00104615001401524!GO:0030176;integral to endoplasmic reticulum membrane;0.00105047027432202!GO:0005525;GTP binding;0.00105170320281655!GO:0005885;Arp2/3 protein complex;0.00107297199252735!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00108489101748428!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.0011632164968838!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.0011632164968838!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.0011632164968838!GO:0043021;ribonucleoprotein binding;0.00124242691659067!GO:0015980;energy derivation by oxidation of organic compounds;0.00124605969246108!GO:0006650;glycerophospholipid metabolic process;0.00136481522981325!GO:0006383;transcription from RNA polymerase III promoter;0.0013733386687046!GO:0003678;DNA helicase activity;0.00147609121134086!GO:0051252;regulation of RNA metabolic process;0.00154162382801221!GO:0006268;DNA unwinding during replication;0.00155213935844849!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0015759955477238!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0015759955477238!GO:0019899;enzyme binding;0.00159842071382622!GO:0046483;heterocycle metabolic process;0.00161946589011376!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00164348898841466!GO:0050789;regulation of biological process;0.00178124487787574!GO:0007264;small GTPase mediated signal transduction;0.00188136437132132!GO:0046467;membrane lipid biosynthetic process;0.00188820952497319!GO:0048487;beta-tubulin binding;0.00188820952497319!GO:0006405;RNA export from nucleus;0.00197045990098773!GO:0006350;transcription;0.00197328386567321!GO:0006695;cholesterol biosynthetic process;0.0019940245562977!GO:0006270;DNA replication initiation;0.00211118020362455!GO:0044262;cellular carbohydrate metabolic process;0.00214568144708076!GO:0031323;regulation of cellular metabolic process;0.00215217939603947!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00231831078108732!GO:0015002;heme-copper terminal oxidase activity;0.00231831078108732!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00231831078108732!GO:0004129;cytochrome-c oxidase activity;0.00231831078108732!GO:0035258;steroid hormone receptor binding;0.00233253276214993!GO:0001558;regulation of cell growth;0.0023782183401506!GO:0005905;coated pit;0.00246418528207306!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00252931858525119!GO:0030384;phosphoinositide metabolic process;0.00254575461607982!GO:0006506;GPI anchor biosynthetic process;0.00269315308383857!GO:0006672;ceramide metabolic process;0.0027356455833156!GO:0006302;double-strand break repair;0.00277895954555632!GO:0005774;vacuolar membrane;0.00278882447482877!GO:0000059;protein import into nucleus, docking;0.00289107307040421!GO:0003711;transcription elongation regulator activity;0.00295603194666928!GO:0048519;negative regulation of biological process;0.00295996183540932!GO:0046519;sphingoid metabolic process;0.00307057825713447!GO:0006733;oxidoreduction coenzyme metabolic process;0.00314029213725922!GO:0045454;cell redox homeostasis;0.00314029213725922!GO:0043488;regulation of mRNA stability;0.00316186009761119!GO:0043487;regulation of RNA stability;0.00316186009761119!GO:0004576;oligosaccharyl transferase activity;0.00329080022894317!GO:0008287;protein serine/threonine phosphatase complex;0.00329080022894317!GO:0008250;oligosaccharyl transferase complex;0.00332469655200112!GO:0030880;RNA polymerase complex;0.00349574336749593!GO:0007006;mitochondrial membrane organization and biogenesis;0.0037653204694782!GO:0031968;organelle outer membrane;0.00381779714729128!GO:0005637;nuclear inner membrane;0.00382667292115965!GO:0006730;one-carbon compound metabolic process;0.0039046637847305!GO:0006352;transcription initiation;0.00404459396137105!GO:0006611;protein export from nucleus;0.0040897113176644!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00411303421991762!GO:0006612;protein targeting to membrane;0.00431558261406638!GO:0006505;GPI anchor metabolic process;0.0045152471153357!GO:0019867;outer membrane;0.00453727783369047!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00466866566193846!GO:0065009;regulation of a molecular function;0.00502915485534946!GO:0004527;exonuclease activity;0.00502915485534946!GO:0008610;lipid biosynthetic process;0.00504155888819764!GO:0030137;COPI-coated vesicle;0.0052760889160682!GO:0000123;histone acetyltransferase complex;0.0053458539383928!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00559701420436231!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.00614322574732453!GO:0043414;biopolymer methylation;0.0063292117149954!GO:0031124;mRNA 3'-end processing;0.00643765563060585!GO:0003887;DNA-directed DNA polymerase activity;0.00648462372918516!GO:0005741;mitochondrial outer membrane;0.00655077051417976!GO:0044437;vacuolar part;0.00661589252622119!GO:0008022;protein C-terminus binding;0.00669985017231399!GO:0000030;mannosyltransferase activity;0.00675090369464099!GO:0008361;regulation of cell size;0.00678412644808192!GO:0006767;water-soluble vitamin metabolic process;0.00680711685829681!GO:0006082;organic acid metabolic process;0.00689948206785121!GO:0006626;protein targeting to mitochondrion;0.00689948206785121!GO:0032561;guanyl ribonucleotide binding;0.00689948206785121!GO:0019001;guanyl nucleotide binding;0.00689948206785121!GO:0006891;intra-Golgi vesicle-mediated transport;0.00719030656236588!GO:0007088;regulation of mitosis;0.00719030656236588!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00727112057596134!GO:0000428;DNA-directed RNA polymerase complex;0.00727112057596134!GO:0006769;nicotinamide metabolic process;0.00727112057596134!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.00730182534595895!GO:0044452;nucleolar part;0.00730896964283785!GO:0031072;heat shock protein binding;0.00752911173315598!GO:0030663;COPI coated vesicle membrane;0.00752911173315598!GO:0030126;COPI vesicle coat;0.00752911173315598!GO:0043189;H4/H2A histone acetyltransferase complex;0.00755327241493545!GO:0043596;nuclear replication fork;0.00759912890754595!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00793482113033463!GO:0030133;transport vesicle;0.00815577898739252!GO:0019752;carboxylic acid metabolic process;0.0082680233889758!GO:0006740;NADPH regeneration;0.00828633776580158!GO:0006098;pentose-phosphate shunt;0.00828633776580158!GO:0005853;eukaryotic translation elongation factor 1 complex;0.00829835402058356!GO:0032259;methylation;0.0084106039811877!GO:0005869;dynactin complex;0.00847067929113159!GO:0016049;cell growth;0.00863369885987649!GO:0030118;clathrin coat;0.00875772911811729!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00879900026829195!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.00879900026829195!GO:0008139;nuclear localization sequence binding;0.0088972084313541!GO:0006595;polyamine metabolic process;0.00902544248719947!GO:0008276;protein methyltransferase activity;0.00907569153590329!GO:0016859;cis-trans isomerase activity;0.00946214133481752!GO:0016272;prefoldin complex;0.00951860793616066!GO:0019318;hexose metabolic process;0.00977804044742072!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00989060715307927!GO:0000209;protein polyubiquitination;0.0104972499263854!GO:0005669;transcription factor TFIID complex;0.0107670690912922!GO:0005996;monosaccharide metabolic process;0.0110316647726635!GO:0008632;apoptotic program;0.0112325608122259!GO:0016628;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;0.0117266472495917!GO:0006338;chromatin remodeling;0.0117629693702331!GO:0000049;tRNA binding;0.0120371234402835!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.01204793076895!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.012370841427812!GO:0008601;protein phosphatase type 2A regulator activity;0.0124109342254334!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0124932165266561!GO:0016044;membrane organization and biogenesis;0.0125167703206566!GO:0003690;double-stranded DNA binding;0.0125912324640271!GO:0007040;lysosome organization and biogenesis;0.012707206724323!GO:0004532;exoribonuclease activity;0.0128619487010594!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0128619487010594!GO:0004674;protein serine/threonine kinase activity;0.0130761174348359!GO:0006289;nucleotide-excision repair;0.0133538376582174!GO:0030659;cytoplasmic vesicle membrane;0.0133919516000805!GO:0010468;regulation of gene expression;0.0134195619095486!GO:0040029;regulation of gene expression, epigenetic;0.0136948743504659!GO:0042770;DNA damage response, signal transduction;0.0137501255234259!GO:0005874;microtubule;0.0137763382031398!GO:0019843;rRNA binding;0.0139036897372219!GO:0016301;kinase activity;0.0142834025790111!GO:0005791;rough endoplasmic reticulum;0.0142834025790111!GO:0000082;G1/S transition of mitotic cell cycle;0.0144173884794137!GO:0004003;ATP-dependent DNA helicase activity;0.0149885027092639!GO:0004722;protein serine/threonine phosphatase activity;0.0149902723707429!GO:0008637;apoptotic mitochondrial changes;0.0150590707546144!GO:0046966;thyroid hormone receptor binding;0.0150590707546144!GO:0047485;protein N-terminus binding;0.0150735481897332!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.015081988332418!GO:0018196;peptidyl-asparagine modification;0.0154735947468404!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0154735947468404!GO:0007052;mitotic spindle organization and biogenesis;0.0155979683061188!GO:0007265;Ras protein signal transduction;0.0158153112917976!GO:0005832;chaperonin-containing T-complex;0.0160944562144947!GO:0040008;regulation of growth;0.0162876330209281!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.0163413332136639!GO:0019362;pyridine nucleotide metabolic process;0.0166608199224571!GO:0030658;transport vesicle membrane;0.0169268678625695!GO:0015631;tubulin binding;0.0170805552322438!GO:0007021;tubulin folding;0.0171173961383005!GO:0031123;RNA 3'-end processing;0.0171311288687291!GO:0006778;porphyrin metabolic process;0.017171616260246!GO:0033013;tetrapyrrole metabolic process;0.017171616260246!GO:0045792;negative regulation of cell size;0.0173125783337544!GO:0031902;late endosome membrane;0.0176103886259981!GO:0000086;G2/M transition of mitotic cell cycle;0.017825134211209!GO:0007050;cell cycle arrest;0.0178287774945977!GO:0035267;NuA4 histone acetyltransferase complex;0.0184002739091556!GO:0050662;coenzyme binding;0.0188900769860248!GO:0044433;cytoplasmic vesicle part;0.0189874393681753!GO:0006509;membrane protein ectodomain proteolysis;0.0194956663286125!GO:0033619;membrane protein proteolysis;0.0194956663286125!GO:0005765;lysosomal membrane;0.019561475988882!GO:0009112;nucleobase metabolic process;0.0196237039496628!GO:0016251;general RNA polymerase II transcription factor activity;0.0199369107116304!GO:0009303;rRNA transcription;0.0201864538483319!GO:0030132;clathrin coat of coated pit;0.0205849383321259!GO:0007033;vacuole organization and biogenesis;0.0211430624935072!GO:0030518;steroid hormone receptor signaling pathway;0.02164139134284!GO:0030308;negative regulation of cell growth;0.0217907029077189!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0219843415476324!GO:0006497;protein amino acid lipidation;0.0222659621858861!GO:0030119;AP-type membrane coat adaptor complex;0.0224293973152167!GO:0016791;phosphoric monoester hydrolase activity;0.0228700502900921!GO:0030131;clathrin adaptor complex;0.0229585636981602!GO:0045941;positive regulation of transcription;0.0229585636981602!GO:0006378;mRNA polyadenylation;0.0229585636981602!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0230218909836292!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0230506322995503!GO:0000792;heterochromatin;0.0234962482400969!GO:0008538;proteasome activator activity;0.0236274805839417!GO:0000096;sulfur amino acid metabolic process;0.0236732305717831!GO:0000776;kinetochore;0.0237094508909532!GO:0006354;RNA elongation;0.0240813149337417!GO:0032774;RNA biosynthetic process;0.0248346327644662!GO:0008286;insulin receptor signaling pathway;0.0248696490237931!GO:0042987;amyloid precursor protein catabolic process;0.0249472531178716!GO:0051052;regulation of DNA metabolic process;0.0249548748651529!GO:0004860;protein kinase inhibitor activity;0.0256045332110519!GO:0030145;manganese ion binding;0.0259305907686486!GO:0050178;phenylpyruvate tautomerase activity;0.0259399789294712!GO:0006779;porphyrin biosynthetic process;0.0259399789294712!GO:0033014;tetrapyrrole biosynthetic process;0.0259399789294712!GO:0006351;transcription, DNA-dependent;0.0259725310254304!GO:0012506;vesicle membrane;0.026711318766299!GO:0001836;release of cytochrome c from mitochondria;0.0268032033558458!GO:0006144;purine base metabolic process;0.0271475596103466!GO:0030660;Golgi-associated vesicle membrane;0.027546025637862!GO:0006310;DNA recombination;0.0276919701711175!GO:0000163;protein phosphatase type 1 activity;0.0283651669939908!GO:0006066;alcohol metabolic process;0.0290687804572439!GO:0043022;ribosome binding;0.0291179448935842!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0294255329271683!GO:0009304;tRNA transcription;0.0296297307851191!GO:0046822;regulation of nucleocytoplasmic transport;0.0300485874867343!GO:0030521;androgen receptor signaling pathway;0.0302173251758666!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0302665231579522!GO:0005876;spindle microtubule;0.0306232919782615!GO:0006643;membrane lipid metabolic process;0.0307590862767238!GO:0007059;chromosome segregation;0.0312422085450974!GO:0000152;nuclear ubiquitin ligase complex;0.0312711685695091!GO:0048500;signal recognition particle;0.0313462839538442!GO:0051287;NAD binding;0.0321281922531533!GO:0017166;vinculin binding;0.0323993250092579!GO:0031227;intrinsic to endoplasmic reticulum membrane;0.0324343490493454!GO:0006275;regulation of DNA replication;0.0324356780394239!GO:0031371;ubiquitin conjugating enzyme complex;0.0325177314460041!GO:0005784;translocon complex;0.0325245069454023!GO:0043491;protein kinase B signaling cascade;0.0328127932437668!GO:0000287;magnesium ion binding;0.0328529948012102!GO:0016584;nucleosome positioning;0.0335655860828282!GO:0045926;negative regulation of growth;0.0335655860828282!GO:0006376;mRNA splice site selection;0.0335655860828282!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0335655860828282!GO:0046426;negative regulation of JAK-STAT cascade;0.0343675107575274!GO:0043601;nuclear replisome;0.0346175860231651!GO:0030894;replisome;0.0346175860231651!GO:0045045;secretory pathway;0.0353604919603509!GO:0031570;DNA integrity checkpoint;0.0354656452078465!GO:0008180;signalosome;0.0355957992413454!GO:0006516;glycoprotein catabolic process;0.0357552057268374!GO:0000118;histone deacetylase complex;0.0357788380706675!GO:0005680;anaphase-promoting complex;0.0359666800949574!GO:0009116;nucleoside metabolic process;0.0360181248953571!GO:0048037;cofactor binding;0.037350193980985!GO:0016311;dephosphorylation;0.0374740960377049!GO:0009451;RNA modification;0.0375689180209188!GO:0008312;7S RNA binding;0.0380827002820344!GO:0030911;TPR domain binding;0.0385670012153773!GO:0006220;pyrimidine nucleotide metabolic process;0.038617985829625!GO:0007346;regulation of progression through mitotic cell cycle;0.0389773962112864!GO:0045892;negative regulation of transcription, DNA-dependent;0.0389773962112864!GO:0007093;mitotic cell cycle checkpoint;0.0391704043570099!GO:0005777;peroxisome;0.0392226498519266!GO:0042579;microbody;0.0392226498519266!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0398049656199017!GO:0046982;protein heterodimerization activity;0.0401492879167644!GO:0000159;protein phosphatase type 2A complex;0.0404022658500936!GO:0006739;NADP metabolic process;0.0404022658500936!GO:0006644;phospholipid metabolic process;0.0418861374153599!GO:0031628;opioid receptor binding;0.0418861374153599!GO:0031852;mu-type opioid receptor binding;0.0418861374153599!GO:0007017;microtubule-based process;0.0418861374153599!GO:0004549;tRNA-specific ribonuclease activity;0.0424520797153901!GO:0004448;isocitrate dehydrogenase activity;0.0431627948636145!GO:0000781;chromosome, telomeric region;0.0441209805909824!GO:0032039;integrator complex;0.0445953829475041!GO:0050681;androgen receptor binding;0.0446554100166196!GO:0005665;DNA-directed RNA polymerase II, core complex;0.044758519892667!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.044758519892667!GO:0000178;exosome (RNase complex);0.0454533034093821!GO:0006368;RNA elongation from RNA polymerase II promoter;0.045828290944213!GO:0000228;nuclear chromosome;0.0460280256402674!GO:0030149;sphingolipid catabolic process;0.0460280256402674!GO:0000175;3'-5'-exoribonuclease activity;0.0465008450061998!GO:0006520;amino acid metabolic process;0.0467694012779581!GO:0030027;lamellipodium;0.0468641228856413!GO:0030125;clathrin vesicle coat;0.0468940233455026!GO:0030665;clathrin coated vesicle membrane;0.0468940233455026!GO:0042158;lipoprotein biosynthetic process;0.0489437659232078!GO:0042054;histone methyltransferase activity;0.0493562292303451!GO:0042791;5S class rRNA transcription;0.049824386327652!GO:0000127;transcription factor TFIIIC complex;0.049824386327652!GO:0042797;tRNA transcription from RNA polymerase III promoter;0.049824386327652 | |||
|sample_id=13097 | |sample_id=13097 | ||
|sample_note= | |sample_note= | ||
Line 74: | Line 103: | ||
|sample_strain= | |sample_strain= | ||
|sample_tissue=breast | |sample_tissue=breast | ||
|time=00hr00min | |||
|timecourse=MCF7_response_to_EGF,MCF7_response_to_HRG | |||
|top_motifs=PBX1:2.21119871913;NFY{A,B,C}:2.15443189165;MYOD1:1.89656857437;SNAI1..3:1.8668948026;ZEB1:1.83614992585;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.60138800563;POU2F1..3:1.59957254667;SP1:1.40006046345;ARID5B:1.32889924038;FOX{F1,F2,J1}:1.27384771982;XCPE1{core}:1.20493655574;ELK1,4_GABP{A,B1}:1.19623254422;ONECUT1,2:1.18398091035;GFI1:1.14060348306;LMO2:1.07820157896;bHLH_family:1.05452075556;ESRRA:1.01499302402;NRF1:0.979012047786;STAT1,3:0.970942244004;LHX3,4:0.897823704534;VSX1,2:0.866079530803;SOX{8,9,10}:0.835259954056;IKZF1:0.720437321949;YY1:0.720353393957;E2F1..5:0.705723151678;TFDP1:0.659531563914;FOXQ1:0.658197538792;MYB:0.648500828487;HOXA9_MEIS1:0.630245475641;EGR1..3:0.625874444155;PPARG:0.615594505249;TFAP2{A,C}:0.563499461354;PAX5:0.524787010128;PAX1,9:0.518941276107;NANOG:0.510040877755;FOXL1:0.498960056429;FOX{I1,J2}:0.498162913168;ESR1:0.483885978072;MED-1{core}:0.43616101318;NFE2L1:0.429822121991;BREu{core}:0.390375342173;TP53:0.385376647701;POU1F1:0.325370218857;OCT4_SOX2{dimer}:0.291320173463;FOXN1:0.28659471442;ZNF143:0.254753309968;TBP:0.24735022282;GTF2A1,2:0.239754042808;LEF1_TCF7_TCF7L1,2:0.23464993802;PITX1..3:0.220364580169;TEAD1:0.219479985073;ZNF423:0.213813824334;ZNF148:0.203926427389;CDX1,2,4:0.198303912911;TFAP2B:0.179176686873;SREBF1,2:0.172156855993;STAT5{A,B}:0.165595214091;REST:0.160155675572;NR5A1,2:0.156207279617;TOPORS:0.140272120719;RFX1:0.13970020328;AR:0.130472349165;RORA:0.122449127967;RBPJ:0.115206000882;TFCP2:0.113629509164;RXRA_VDR{dimer}:0.0940997918299;HIF1A:0.0888104202808;HAND1,2:0.0777008097367;HNF1A:0.0730294085441;HES1:0.0727338978496;HOX{A4,D4}:0.0275478361255;NKX6-1,2:0.0173935092896;FOS_FOS{B,L1}_JUN{B,D}:0.0157684550697;HOX{A6,A7,B6,B7}:0.0108471032422;FOXA2:0.00868241106041;RFX2..5_RFXANK_RFXAP:-0.00726507859967;FOX{D1,D2}:-0.0172734585338;HNF4A_NR2F1,2:-0.0175355488837;EBF1:-0.042410483615;ZBTB6:-0.0443143747614;HIC1:-0.0751706071416;ATF5_CREB3:-0.09342938975;PAX2:-0.122256724378;HMX1:-0.132726276012;NFE2:-0.141316694257;RREB1:-0.160364009054;MTF1:-0.167206573858;HOX{A5,B5}:-0.169988722248;UFEwm:-0.172177233641;ATF2:-0.178497260024;TBX4,5:-0.185342605446;ALX1:-0.200874495778;TLX2:-0.201384491006;EN1,2:-0.217213769503;BACH2:-0.247642074814;ZNF384:-0.254716792522;FOSL2:-0.259834886209;TLX1..3_NFIC{dimer}:-0.26562624012;GATA6:-0.267698012525;ZFP161:-0.279638458113;HSF1,2:-0.312845692888;ATF6:-0.333927589325;CREB1:-0.342626921702;ELF1,2,4:-0.364240227208;SOX5:-0.365691699351;ADNP_IRX_SIX_ZHX:-0.372954353044;POU3F1..4:-0.376877260154;NFE2L2:-0.376918978073;ZIC1..3:-0.409805848326;CDC5L:-0.416286790201;GTF2I:-0.433633883745;JUN:-0.441918454035;TFAP4:-0.442201481456;MAZ:-0.450692436014;FOXM1:-0.451644631219;CUX2:-0.465564907641;IKZF2:-0.468809520907;DBP:-0.470211766512;MEF2{A,B,C,D}:-0.471018207812;GZF1:-0.48278700671;NFIL3:-0.505464650548;SPIB:-0.537079080169;NFKB1_REL_RELA:-0.538815800129;NKX2-2,8:-0.557205295106;EP300:-0.572745245273;NKX2-3_NKX2-5:-0.604781484561;FOXD3:-0.605127807865;SOX2:-0.607252381672;TAL1_TCF{3,4,12}:-0.624167252146;NR6A1:-0.626296931488;ALX4:-0.631292994951;MAFB:-0.633521939093;NR1H4:-0.644396314868;PAX6:-0.654698421383;ATF4:-0.658869035893;RUNX1..3:-0.665672387823;NANOG{mouse}:-0.690375162858;HLF:-0.70858867639;FOXP1:-0.713285975442;CRX:-0.735434892128;PRRX1,2:-0.740878221543;PATZ1:-0.751189810099;SPI1:-0.765531891201;IRF7:-0.770588096034;ETS1,2:-0.832097375455;AHR_ARNT_ARNT2:-0.841887947004;MYFfamily:-0.851701633574;SRF:-0.866200878824;POU6F1:-0.888950350313;NKX3-2:-0.892174842609;EVI1:-0.905579190179;SOX17:-0.951308672182;POU5F1:-0.954826807634;NHLH1,2:-0.956487815391;CEBPA,B_DDIT3:-0.966490321542;GFI1B:-0.9852346573;IRF1,2:-1.00668549988;MTE{core}:-1.00752640415;TGIF1:-1.01366577883;ZBTB16:-1.04019216397;XBP1:-1.04670307416;MZF1:-1.0811913966;NFIX:-1.08997731908;STAT2,4,6:-1.0970011131;PAX8:-1.10342986125;FOXO1,3,4:-1.11862422947;GLI1..3:-1.16050196587;ZNF238:-1.16172956593;DMAP1_NCOR{1,2}_SMARC:-1.19211608843;BPTF:-1.20223736743;NR3C1:-1.20491450975;PAX3,7:-1.23991658797;KLF4:-1.28746268047;MYBL2:-1.31685456794;PAX4:-1.32101503169;NFATC1..3:-1.33465541845;PDX1:-1.37685365748;RXR{A,B,G}:-1.43383422327;AIRE:-1.45334082309;NKX3-1:-1.50975095081;HBP1_HMGB_SSRP1_UBTF:-1.51948453037;T:-1.54888089048;TEF:-1.57306934114;GATA4:-1.60084881889;SMAD1..7,9:-1.60172697006;GCM1,2:-1.63723633645;SPZ1:-1.67261638085;FOXP3:-1.70780683896;PRDM1:-1.88682540727;RXR{A,B,G}_{NR1H2,PPAR}dimers:-1.90616239609;NKX2-1,4:-1.99404470512;HMGA1,2:-2.25937327929 | |top_motifs=PBX1:2.21119871913;NFY{A,B,C}:2.15443189165;MYOD1:1.89656857437;SNAI1..3:1.8668948026;ZEB1:1.83614992585;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.60138800563;POU2F1..3:1.59957254667;SP1:1.40006046345;ARID5B:1.32889924038;FOX{F1,F2,J1}:1.27384771982;XCPE1{core}:1.20493655574;ELK1,4_GABP{A,B1}:1.19623254422;ONECUT1,2:1.18398091035;GFI1:1.14060348306;LMO2:1.07820157896;bHLH_family:1.05452075556;ESRRA:1.01499302402;NRF1:0.979012047786;STAT1,3:0.970942244004;LHX3,4:0.897823704534;VSX1,2:0.866079530803;SOX{8,9,10}:0.835259954056;IKZF1:0.720437321949;YY1:0.720353393957;E2F1..5:0.705723151678;TFDP1:0.659531563914;FOXQ1:0.658197538792;MYB:0.648500828487;HOXA9_MEIS1:0.630245475641;EGR1..3:0.625874444155;PPARG:0.615594505249;TFAP2{A,C}:0.563499461354;PAX5:0.524787010128;PAX1,9:0.518941276107;NANOG:0.510040877755;FOXL1:0.498960056429;FOX{I1,J2}:0.498162913168;ESR1:0.483885978072;MED-1{core}:0.43616101318;NFE2L1:0.429822121991;BREu{core}:0.390375342173;TP53:0.385376647701;POU1F1:0.325370218857;OCT4_SOX2{dimer}:0.291320173463;FOXN1:0.28659471442;ZNF143:0.254753309968;TBP:0.24735022282;GTF2A1,2:0.239754042808;LEF1_TCF7_TCF7L1,2:0.23464993802;PITX1..3:0.220364580169;TEAD1:0.219479985073;ZNF423:0.213813824334;ZNF148:0.203926427389;CDX1,2,4:0.198303912911;TFAP2B:0.179176686873;SREBF1,2:0.172156855993;STAT5{A,B}:0.165595214091;REST:0.160155675572;NR5A1,2:0.156207279617;TOPORS:0.140272120719;RFX1:0.13970020328;AR:0.130472349165;RORA:0.122449127967;RBPJ:0.115206000882;TFCP2:0.113629509164;RXRA_VDR{dimer}:0.0940997918299;HIF1A:0.0888104202808;HAND1,2:0.0777008097367;HNF1A:0.0730294085441;HES1:0.0727338978496;HOX{A4,D4}:0.0275478361255;NKX6-1,2:0.0173935092896;FOS_FOS{B,L1}_JUN{B,D}:0.0157684550697;HOX{A6,A7,B6,B7}:0.0108471032422;FOXA2:0.00868241106041;RFX2..5_RFXANK_RFXAP:-0.00726507859967;FOX{D1,D2}:-0.0172734585338;HNF4A_NR2F1,2:-0.0175355488837;EBF1:-0.042410483615;ZBTB6:-0.0443143747614;HIC1:-0.0751706071416;ATF5_CREB3:-0.09342938975;PAX2:-0.122256724378;HMX1:-0.132726276012;NFE2:-0.141316694257;RREB1:-0.160364009054;MTF1:-0.167206573858;HOX{A5,B5}:-0.169988722248;UFEwm:-0.172177233641;ATF2:-0.178497260024;TBX4,5:-0.185342605446;ALX1:-0.200874495778;TLX2:-0.201384491006;EN1,2:-0.217213769503;BACH2:-0.247642074814;ZNF384:-0.254716792522;FOSL2:-0.259834886209;TLX1..3_NFIC{dimer}:-0.26562624012;GATA6:-0.267698012525;ZFP161:-0.279638458113;HSF1,2:-0.312845692888;ATF6:-0.333927589325;CREB1:-0.342626921702;ELF1,2,4:-0.364240227208;SOX5:-0.365691699351;ADNP_IRX_SIX_ZHX:-0.372954353044;POU3F1..4:-0.376877260154;NFE2L2:-0.376918978073;ZIC1..3:-0.409805848326;CDC5L:-0.416286790201;GTF2I:-0.433633883745;JUN:-0.441918454035;TFAP4:-0.442201481456;MAZ:-0.450692436014;FOXM1:-0.451644631219;CUX2:-0.465564907641;IKZF2:-0.468809520907;DBP:-0.470211766512;MEF2{A,B,C,D}:-0.471018207812;GZF1:-0.48278700671;NFIL3:-0.505464650548;SPIB:-0.537079080169;NFKB1_REL_RELA:-0.538815800129;NKX2-2,8:-0.557205295106;EP300:-0.572745245273;NKX2-3_NKX2-5:-0.604781484561;FOXD3:-0.605127807865;SOX2:-0.607252381672;TAL1_TCF{3,4,12}:-0.624167252146;NR6A1:-0.626296931488;ALX4:-0.631292994951;MAFB:-0.633521939093;NR1H4:-0.644396314868;PAX6:-0.654698421383;ATF4:-0.658869035893;RUNX1..3:-0.665672387823;NANOG{mouse}:-0.690375162858;HLF:-0.70858867639;FOXP1:-0.713285975442;CRX:-0.735434892128;PRRX1,2:-0.740878221543;PATZ1:-0.751189810099;SPI1:-0.765531891201;IRF7:-0.770588096034;ETS1,2:-0.832097375455;AHR_ARNT_ARNT2:-0.841887947004;MYFfamily:-0.851701633574;SRF:-0.866200878824;POU6F1:-0.888950350313;NKX3-2:-0.892174842609;EVI1:-0.905579190179;SOX17:-0.951308672182;POU5F1:-0.954826807634;NHLH1,2:-0.956487815391;CEBPA,B_DDIT3:-0.966490321542;GFI1B:-0.9852346573;IRF1,2:-1.00668549988;MTE{core}:-1.00752640415;TGIF1:-1.01366577883;ZBTB16:-1.04019216397;XBP1:-1.04670307416;MZF1:-1.0811913966;NFIX:-1.08997731908;STAT2,4,6:-1.0970011131;PAX8:-1.10342986125;FOXO1,3,4:-1.11862422947;GLI1..3:-1.16050196587;ZNF238:-1.16172956593;DMAP1_NCOR{1,2}_SMARC:-1.19211608843;BPTF:-1.20223736743;NR3C1:-1.20491450975;PAX3,7:-1.23991658797;KLF4:-1.28746268047;MYBL2:-1.31685456794;PAX4:-1.32101503169;NFATC1..3:-1.33465541845;PDX1:-1.37685365748;RXR{A,B,G}:-1.43383422327;AIRE:-1.45334082309;NKX3-1:-1.50975095081;HBP1_HMGB_SSRP1_UBTF:-1.51948453037;T:-1.54888089048;TEF:-1.57306934114;GATA4:-1.60084881889;SMAD1..7,9:-1.60172697006;GCM1,2:-1.63723633645;SPZ1:-1.67261638085;FOXP3:-1.70780683896;PRDM1:-1.88682540727;RXR{A,B,G}_{NR1H2,PPAR}dimers:-1.90616239609;NKX2-1,4:-1.99404470512;HMGA1,2:-2.25937327929 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:13097-140D1;search_select_hide=table117:FF:13097-140D1 | |||
}} | }} |
Latest revision as of 18:51, 4 June 2020
Name: | MCF7 breast cancer cell line response to EGF1 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs12475 |
Sample type: | time courses |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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RNA-Seq Accession numbers | ||||||||||||||||||||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12475
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12475
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.172 |
10 | 10 | 0.619 |
100 | 100 | 0.571 |
101 | 101 | 0.139 |
102 | 102 | 0.334 |
103 | 103 | 0.165 |
104 | 104 | 0.872 |
105 | 105 | 0.154 |
106 | 106 | 0.0264 |
107 | 107 | 0.0823 |
108 | 108 | 0.665 |
109 | 109 | 0.092 |
11 | 11 | 0.505 |
110 | 110 | 0.976 |
111 | 111 | 0.0279 |
112 | 112 | 0.24 |
113 | 113 | 0.0848 |
114 | 114 | 0.0131 |
115 | 115 | 0.246 |
116 | 116 | 0.547 |
117 | 117 | 0.387 |
118 | 118 | 0.319 |
119 | 119 | 0.313 |
12 | 12 | 0.788 |
120 | 120 | 0.864 |
121 | 121 | 0.805 |
122 | 122 | 0.453 |
123 | 123 | 0.101 |
124 | 124 | 0.12 |
125 | 125 | 0.291 |
126 | 126 | 0.779 |
127 | 127 | 0.802 |
128 | 128 | 0.0696 |
129 | 129 | 0.505 |
13 | 13 | 0.572 |
130 | 130 | 0.00194 |
131 | 131 | 0.21 |
132 | 132 | 0.814 |
133 | 133 | 0.0092 |
134 | 134 | 0.154 |
135 | 135 | 0.299 |
136 | 136 | 0.00155 |
137 | 137 | 0.0975 |
138 | 138 | 0.133 |
139 | 139 | 0.0596 |
14 | 14 | 1 |
140 | 140 | 0.299 |
141 | 141 | 0.789 |
142 | 142 | 0.267 |
143 | 143 | 0.0359 |
144 | 144 | 0.345 |
145 | 145 | 0.273 |
146 | 146 | 0.488 |
147 | 147 | 0.746 |
148 | 148 | 4.61885e-4 |
149 | 149 | 0.215 |
15 | 15 | 0.404 |
150 | 150 | 0.978 |
151 | 151 | 0.157 |
152 | 152 | 0.778 |
153 | 153 | 0.0883 |
154 | 154 | 0.394 |
155 | 155 | 0.0492 |
156 | 156 | 0.768 |
157 | 157 | 0.423 |
158 | 158 | 0.268 |
159 | 159 | 0.655 |
16 | 16 | 0.491 |
160 | 160 | 0.441 |
161 | 161 | 0.639 |
162 | 162 | 0.893 |
163 | 163 | 0.667 |
164 | 164 | 0.449 |
165 | 165 | 0.37 |
166 | 166 | 0.157 |
167 | 167 | 0.891 |
168 | 168 | 0.235 |
169 | 169 | 0.967 |
17 | 17 | 0.829 |
18 | 18 | 0.0868 |
19 | 19 | 0.236 |
2 | 2 | 0.44 |
20 | 20 | 0.28 |
21 | 21 | 0.248 |
22 | 22 | 0.637 |
23 | 23 | 0.00184 |
24 | 24 | 0.946 |
25 | 25 | 0.937 |
26 | 26 | 0.317 |
27 | 27 | 0.571 |
28 | 28 | 0.845 |
29 | 29 | 0.842 |
3 | 3 | 0.112 |
30 | 30 | 0.436 |
31 | 31 | 0.471 |
32 | 32 | 0.152 |
33 | 33 | 0.523 |
34 | 34 | 0.242 |
35 | 35 | 0.103 |
36 | 36 | 0.281 |
37 | 37 | 0.16 |
38 | 38 | 0.994 |
39 | 39 | 0.516 |
4 | 4 | 0.621 |
40 | 40 | 0.243 |
41 | 41 | 0.174 |
42 | 42 | 0.194 |
43 | 43 | 0.104 |
44 | 44 | 0.266 |
45 | 45 | 0.903 |
46 | 46 | 0.139 |
47 | 47 | 0.883 |
48 | 48 | 0.977 |
49 | 49 | 0.146 |
5 | 5 | 0.126 |
50 | 50 | 0.479 |
51 | 51 | 0.539 |
52 | 52 | 0.313 |
53 | 53 | 0.132 |
54 | 54 | 0.377 |
55 | 55 | 0.439 |
56 | 56 | 0.41 |
57 | 57 | 0.347 |
58 | 58 | 0.297 |
59 | 59 | 0.317 |
6 | 6 | 0.531 |
60 | 60 | 0.0373 |
61 | 61 | 0.721 |
62 | 62 | 0.068 |
63 | 63 | 0.239 |
64 | 64 | 0.784 |
65 | 65 | 0.268 |
66 | 66 | 0.0307 |
67 | 67 | 0.514 |
68 | 68 | 0.961 |
69 | 69 | 0.639 |
7 | 7 | 0.655 |
70 | 70 | 0.0424 |
71 | 71 | 0.361 |
72 | 72 | 0.578 |
73 | 73 | 0.791 |
74 | 74 | 0.0659 |
75 | 75 | 0.99 |
76 | 76 | 0.979 |
77 | 77 | 0.411 |
78 | 78 | 0.944 |
79 | 79 | 0.263 |
8 | 8 | 0.415 |
80 | 80 | 0.0469 |
81 | 81 | 0.134 |
82 | 82 | 0.286 |
83 | 83 | 0.367 |
84 | 84 | 0.818 |
85 | 85 | 0.0701 |
86 | 86 | 0.464 |
87 | 87 | 0.00296 |
88 | 88 | 0.667 |
89 | 89 | 0.0853 |
9 | 9 | 0.151 |
90 | 90 | 7.07333e-5 |
91 | 91 | 0.0964 |
92 | 92 | 0.0211 |
93 | 93 | 0.188 |
94 | 94 | 0.121 |
95 | 95 | 0.02 |
96 | 96 | 0.0849 |
97 | 97 | 0.964 |
98 | 98 | 0.28 |
99 | 99 | 0.937 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs12475
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000426 human MCF7 breast cancer cell line 0min after EGF1 treatment sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000066 (epithelial cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
14566 (disease of cellular proliferation)
0050687 (cell type cancer)
7 (disease of anatomical entity)
5093 (thoracic cancer)
305 (carcinoma)
299 (adenocarcinoma)
1612 (breast cancer)
UBERON: Anatomy
0000468 (multi-cellular organism)
0000310 (breast)
0002100 (trunk)
0000475 (organism subdivision)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0001062 (anatomical entity)
0009569 (subdivision of trunk)
0001443 (chest)
0000915 (thoracic segment of trunk)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0000350 (experimentally modified sample)
0000344 (0 minute sample)
0000330 (EGF1 treatment sample)
0100093 (MCF-7 cell sample)
0100297 (carcinoma cell line sample)
0101912 (breast adenocarcinoma cell line sample)
0101120 (epithelial cell line sample)
0100816 (breast cell line sample)
0100167 (adenocarcinoma cell line sample)
0100356 (breast cancer cell line sample)
0000426 (human MCF7 breast cancer cell line 0min after EGF1 treatment sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
NA