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{{f5samples
{{f5samples
|ancestors_in_anatomy_facet=UBERON:0000061,UBERON:0000465,UBERON:0000479,UBERON:0001062,UBERON:0002384
|DRA_sample_Accession=CAGE@SAMD00006003
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000004,CL:0000012,CL:0000034,CL:0000037,CL:0000048,CL:0000051,CL:0000063,CL:0000084,CL:0000134,CL:0000144,CL:0000219,CL:0000255,CL:0000542,CL:0000548,CL:0000566,CL:0000723,CL:0000738,CL:0000827,CL:0000837,CL:0000838,CL:0000988,CL:0002031,CL:0002032,CL:0002087,CL:0002320,CL:0002371
|accession_numbers=CAGE;DRX007852;DRR008724;DRZ000149;DRZ001534;DRZ011499;DRZ012884
|ancestors_in_disease_facet=DOID:0050686,DOID:0060083,DOID:1036,DOID:1240,DOID:14566,DOID:162,DOID:2531,DOID:4
|ancestors_in_anatomy_facet=
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0002371,CL:0000542,CL:0000219,CL:0000738,CL:0002087,CL:0002242,CL:0000255,CL:0000084
|ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:14566,DOID:0060083,DOID:1240,DOID:1036
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100737,FF:0101035,FF:0103505
|comment=
|comment=
|created_by=
|created_by=
|creation_date=
|creation_date=
|data_phase=2
|datafreeze_phase=2
|def=
|def=
|expression_enrichment_score=chr5:133451294..133451310,+!p2@TCF7!2.18!149.20!TCF7;;chr9:77112244..77112262,+!p1@RORB!1.98!106.28!RORB;;chr4:109087445..109087463,-!p1@LEF1!1.97!93.00!LEF1;;chr8:60031619..60031676,-!p1@TOX!1.78!125.70!TOX;;chr12:54694653..54694672,-!p2@NFE2!1.78!59.27!NFE2;;chr4:109090075..109090095,-!p2@LEF1!1.76!56.21!LEF1;;chr1:23857698..23857733,-!p1@E2F2!1.75!98.11!E2F2;;chr6:135502501..135502546,+!p1@MYB!1.71!59.27!MYB;;chr6:135502408..135502459,+!p2@MYB!1.61!45.99!MYB;;chr2:74741569..74741620,+!p1@TLX2!1.59!37.81!TLX2;;chr10:8096772..8096787,+!p2@GATA3!1.56!41.90!GATA3;;chr5:133450365..133450444,+!p1@TCF7!1.49!131.83!TCF7;;chr2:100759010..100759035,-!p1@AFF3!1.46!27.59!AFF3;;chr2:68592406..68592424,+!p1@PLEK!1.44!26.57!PLEK;;chr4:109086281..109086319,-!p9@LEF1!1.44!26.57!LEF1;;chr14:99738138..99738163,-!p1@BCL11B!1.44!26.57!BCL11B;;chr4:109089901..109089930,-!p3@LEF1!1.42!25.55!LEF1;;chr1:23857674..23857685,-!p3@E2F2!1.39!23.50!E2F2;;chr1:158978768..158978800,+!p8@IFI16!1.35!21.46!IFI16;;chr19:19779619..19779670,+!p1@ZNF101!1.34!57.23!ZNF101;;chr7:50348268..50348366,+!p4@IKZF1!1.33!20.44!IKZF1;;chr3:18486354..18486377,-!p2@SATB1!1.30!23.50!SATB1;;chr14:75988771..75988826,+!p1@BATF!1.29!24.53!BATF;;chr1:151798546..151798590,-!p2@RORC!1.29!18.39!RORC;;chrY:21906594..21906622,-!p1@KDM5D!1.29!18.39!KDM5D;;chr4:109088940..109089037,-!p4@LEF1!1.29!18.39!LEF1;;chrX:131624056..131624069,-!p2@MBNL3!1.28!24.53!MBNL3;;chr17:42295682..42295731,-!p17@UBTF!1.26!17.37!UBTF;;chr2:214014959..214015006,-!p4@IKZF2!1.24!16.35!IKZF2;;chr21:36421535..36421610,-!p2@RUNX1!1.21!54.16!RUNX1;;chr14:23588242..23588262,-!p1@CEBPE!1.21!15.33!CEBPE;;chr3:141747459..141747475,-!p1@TFDP2!1.19!118.54!TFDP2;;chr12:54694758..54694805,-!p1@NFE2!1.19!17.37!NFE2;;chr2:100759037..100759058,-!p2@AFF3!1.18!14.31!AFF3;;chr6:135502472..135502489,+!p3@MYB!1.18!14.31!MYB;;chr3:141747441..141747452,-!p4@TFDP2!1.15!18.39!TFDP2;;chr3:27763807..27763822,-!p1@EOMES!1.15!13.29!EOMES;;chr14:23588816..23588836,-!p4@CEBPE!1.15!13.29!CEBPE;;chr14:99737850..99737852,-!p3@BCL11B!1.15!13.29!BCL11B;;chr20:42295745..42295765,+!p1@MYBL2!1.13!203.36!MYBL2;;chr4:109088814..109088831,-!p18@LEF1!1.12!12.26!LEF1;;chr6:135513595..135513617,+!p4@MYB!1.12!12.26!MYB;;chr17:7197911..7197964,-!p1@YBX2!1.12!12.26!YBX2;;chr5:176738887..176738934,-!p1@MXD3!1.11!79.71!MXD3;;chr13:41593425..41593480,-!p1@ELF1!1.11!75.62!ELF1;;chr2:100759076..100759088,-!p10@AFF3!1.09!11.24!AFF3;;chr2:242556900..242556916,-!p6@THAP4!1.09!11.24!THAP4;;chr19:19779686..19779697,+!p3@ZNF101!1.06!12.26!ZNF101;;chr17:42295777..42295816,-!p7@UBTF!1.05!12.26!UBTF;;chr1:151032922..151032951,+!p2@MLLT11!1.03!16.35!MLLT11;;chr3:71355163..71355209,-!p5@FOXP1!1.02!13.29!FOXP1;;chr2:74741642..74741658,+!p2@TLX2!1.01!9.20!TLX2;;chr4:109090054..109090073,-!p7@LEF1!1.01!9.20!LEF1;;chr5:142814241..142814278,-!p12@NR3C1!1.01!9.20!NR3C1;;chr1:8934931..8934947,-!p4@ENO1!0.98!28.61!ENO1;;chr2:192015701..192015743,-!p1@STAT4!0.96!11.24!STAT4;;chr4:109087906..109087928,-!p12@LEF1!0.96!8.18!LEF1;;chr4:109088089..109088101,-!p11@LEF1!0.96!8.18!LEF1;;chr10:8100691..8100732,+!p5@GATA3!0.96!8.18!GATA3;;chrY:2803415..2803468,+!p1@ZFY!0.96!8.18!ZFY;;chr1:92949331..92949377,-!p2@GFI1!0.96!8.18!GFI1;;chr21:36421347..36421380,-!p8@RUNX1!0.96!8.18!RUNX1;;chr7:50343634..50343717,+!p2@IKZF1!0.96!8.18!IKZF1;;chr7:50343895..50343936,+!p5@IKZF1!0.96!8.18!IKZF1;;chr9:117150254..117150271,-!p1@AKNA!0.95!22.48!AKNA;;chr3:141868293..141868355,-!p2@TFDP2!0.94!69.49!TFDP2;;chr6:91006518..91006570,-!p1@BACH2!0.92!17.37!BACH2;;chr8:37963466..37963506,+!p3@ASH2L!0.92!9.20!ASH2L;;chr8:102217679..102217719,-!p2@ZNF706!0.91!25.55!ZNF706;;chr2:214015343..214015366,-!p3@IKZF2!0.91!7.15!IKZF2;;chr2:68592394..68592405,+!p2@PLEK!0.91!7.15!PLEK;;chr4:109087885..109087899,-!p23@LEF1!0.91!7.15!LEF1;;chr4:109088863..109088887,-!p24@LEF1!0.91!7.15!LEF1;;chrX:131623982..131624011,-!p6@MBNL3!0.90!10.22!MBNL3;;chr21:36231861..36231877,-!p12@RUNX1!0.90!9.20!RUNX1;;chr6:21597283..21597312,+!p7@SOX4!0.89!9.20!SOX4;;chr11:128563948..128564003,+!p1@FLI1!0.88!83.80!FLI1;;chr6:21597765..21597779,+!p2@SOX4!0.88!56.21!SOX4;;chr1:158979686..158979745,+!p1@IFI16!0.87!220.74!IFI16;;chr19:24097675..24097699,+!p1@ZNF726!0.87!22.48!ZNF726;;chr16:54320675..54320715,-!p1@IRX3!0.87!14.31!IRX3;;chr12:53856284..53856299,+!p3@PCBP2!0.85!18.39!PCBP2;;chr10:8095593..8095625,+!p3@GATA3!0.85!7.15!GATA3;;chr13:41593493..41593506,-!p8@ELF1!0.85!6.13!ELF1;;chr16:29819558..29819572,+!p28@MAZ!0.85!6.13!MAZ;;chr16:85936412..85936431,+!p2@IRF8!0.85!6.13!IRF8;;chr17:38020392..38020477,-!p1@IKZF3!0.85!6.13!IKZF3;;chr7:50343800..50343811,+!p8@IKZF1!0.85!6.13!IKZF1;;chr21:36421147..36421193,-!p10@RUNX1!0.85!6.13!RUNX1;;chr4:109089573..109089585,-!p8@LEF1!0.85!6.13!LEF1;;chr4:109089996..109090012,-!p5@LEF1!0.85!6.13!LEF1;;chr4:109090408..109090441,-!p21@LEF1!0.85!6.13!LEF1;;chr16:29819446..29819471,+!p9@MAZ!0.84!18.39!MAZ;;chr16:54320646..54320672,-!p2@IRX3!0.84!9.20!IRX3;;chr1:8926441..8926473,-!p10@ENO1!0.84!9.20!ENO1;;chr2:192015750..192015793,-!p2@STAT4!0.84!8.18!STAT4;;chr14:55493763..55493824,-!p1@WDHD1!0.83!45.99!WDHD1;;chr19:23299814..23299844,+!p1@ZNF730!0.83!7.15!ZNF730;;chr19:24097706..24097731,+!p2@ZNF726!0.82!11.24!ZNF726;;chr19:20011775..20011800,+!p2@ZNF93!0.81!10.22!ZNF93;;chr3:141820622..141820635,-!p5@TFDP2!0.81!10.22!TFDP2;;chr6:15249128..15249177,+!p4@JARID2!0.81!10.22!JARID2;;chr19:22817119..22817145,+!p1@ZNF492!0.80!9.20!ZNF492;;chr8:81398682..81398697,+!p6@ZBTB10!0.80!7.15!ZBTB10;;chr19:22034809..22034878,-!p2@ZNF43!0.79!19.42!ZNF43;;chr19:22235279..22235301,+!p1@ZNF257!0.79!10.22!ZNF257;;chr12:54785074..54785122,-!p2@ZNF385A!0.79!8.18!ZNF385A;;chr1:8926369..8926385,-!p12@ENO1!0.79!7.15!ENO1;;chr1:151032957..151032968,+!p7@MLLT11!0.79!5.11!MLLT11;;chr1:158978830..158978851,+!p22@IFI16!0.79!5.11!IFI16;;chr5:133477905..133477956,+!p5@TCF7!0.79!5.11!TCF7;;chr8:60031563..60031574,-!p7@TOX!0.79!5.11!TOX;;chr2:100759060..100759073,-!p8@AFF3!0.79!5.11!AFF3;;chr4:109086321..109086357,-!p16@LEF1!0.79!5.11!LEF1;;chr15:60296442..60296464,+!p1@FOXB1!0.79!5.11!FOXB1;;chr16:54319010..54319041,-!p8@IRX3!0.79!5.11!IRX3;;chr16:54320322..54320343,-!p7@IRX3!0.79!5.11!IRX3;;chr16:54964899..54964914,+!p2@IRX5!0.79!5.11!IRX5;;chrY:21906623..21906637,-!p3@KDM5D!0.79!5.11!KDM5D;;chr10:8096631..8096660,+!p1@GATA3!0.78!6.13!GATA3;;chr16:54320101..54320125,-!p4@IRX3!0.77!7.15!IRX3;;chr6:21593973..21593988,+!p1@SOX4!0.76!189.06!SOX4;;chr19:1592714..1592762,-!p1@MBD3!0.76!39.86!MBD3;;chr20:42295713..42295738,+!p2@MYBL2!0.76!30.66!MYBL2;;chr7:148581360..148581425,-!p1@EZH2!0.76!25.55!EZH2;;chr8:42698194..42698239,-!p2@THAP1!0.76!23.50!THAP1;;chr16:54964740..54964789,+!p1@IRX5!0.76!7.15!IRX5;;chr16:29819403..29819442,+!p5@MAZ!0.75!41.90!MAZ;;chr11:6947720..6947812,+!p1@ZNF215!0.75!6.13!ZNF215;;chr16:8962853..8962878,-!p1@CARHSP1!0.74!293.29!CARHSP1;;chr6:20402102..20402152,+!p1@E2F3!0.74!20.44!E2F3;;chr6:31126291..31126399,+!p1@TCF19!0.73!45.99!TCF19;;chr16:29818160..29818188,+!p6@MAZ!0.73!22.48!MAZ;;chr19:11959532..11959593,+!p1@ZNF439!0.73!18.39!ZNF439;;chr7:129251614..129251630,+!p2@NRF1!0.73!11.24!NRF1;;chr1:93544791..93544807,+!p2@MTF2!0.73!7.15!MTF2;;chr22:21355865..21355886,-!p5@THAP7!0.73!5.11!THAP7;;chr22:21355896..21355920,-!p4@THAP7!0.73!5.11!THAP7;;chr1:151032860..151032918,+!p1@MLLT11!0.72!57.23!MLLT11;;chr8:128750555..128750609,+!p5@MYC!0.72!9.20!MYC;;chr11:19263160..19263176,-!p1@E2F8!0.72!5.11!E2F8;;chr19:21106081..21106115,+!p2@ZNF85!0.71!13.29!ZNF85;;chr8:128752850..128752874,+!p12@MYC!0.71!5.11!MYC;;chr5:133450458..133450469,+!p4@TCF7!0.71!4.09!TCF7;;chr5:133451347..133451358,+!p3@TCF7!0.71!4.09!TCF7;;chr5:133477868..133477885,+!p13@TCF7!0.71!4.09!TCF7;;chr5:142814316..142814335,-!p18@NR3C1!0.71!4.09!NR3C1;;chr6:135516978..135516993,+!p7@MYB!0.71!4.09!MYB;;chr7:50344251..50344288,+!p3@IKZF1!0.71!4.09!IKZF1;;chr7:50344289..50344323,+!p1@IKZF1!0.71!4.09!IKZF1;;chr7:64363682..64363692,+!p4@ZNF273!0.71!4.09!ZNF273;;chr8:60031534..60031553,-!p8@TOX!0.71!4.09!TOX;;chr13:79177703..79177729,-!p2@POU4F1!0.71!4.09!POU4F1;;chrX:147582130..147582147,+!p3@AFF2!0.71!4.09!AFF2;;chr9:77112225..77112238,+!p2@RORB!0.71!4.09!RORB;;chr1:26697243..26697258,-!p1@ZNF683!0.71!4.09!ZNF683;;chr20:52226313..52226350,-!p3@ZNF217!0.71!4.09!ZNF217;;chr15:31619140..31619152,+!p11@KLF13!0.71!4.09!KLF13;;chr17:38020481..38020506,-!p7@IKZF3!0.71!4.09!IKZF3;;chr19:23299851..23299880,+!p2@ZNF730!0.71!4.09!ZNF730;;chr2:242556880..242556899,-!p5@THAP4!0.71!4.09!THAP4;;chr3:18487057..18487105,-!p4@SATB1!0.71!4.09!SATB1;;chr4:108991916..108991933,-!p36@LEF1!0.71!4.09!LEF1;;chr4:109086403..109086421,-!p19@LEF1!0.71!4.09!LEF1;;chr4:109087872..109087881,-!p28@LEF1!0.71!4.09!LEF1;;chr4:109088772..109088783,-!p40@LEF1!0.71!4.09!LEF1;;chr4:109089290..109089320,-!p14@LEF1!0.71!4.09!LEF1;;chr7:64126535..64126559,+!p2@ZNF107!0.70!9.20!ZNF107;;chr1:8938709..8938720,-!p3@ENO1!0.69!217.67!ENO1;;chr4:4291837..4291859,-!p2@LYAR!0.69!14.31!LYAR;;chr20:42543506..42543549,+!p2@TOX2!0.69!10.22!TOX2;;chr19:58400372..58400411,-!p1@ZNF814!0.68!22.48!ZNF814;;chr8:128749984..128750033,+!p4@MYC!0.68!15.33!MYC;;chr8:28748099..28748141,+!p2@HMBOX1!0.68!13.29!HMBOX1;;chr1:59249645..59249656,-!p4@JUN!0.67!10.22!JUN;;chr2:214015111..214015179,-!p1@IKZF2!0.67!7.15!IKZF2;;chr21:36260463..36260480,-!p9@RUNX1!0.67!5.11!RUNX1;;chr6:144329500..144329526,-!p4@PLAGL1!0.66!9.20!PLAGL1;;chr19:49140572..49140594,-!p2@DBP!0.66!6.13!DBP;;chr19:12551785..12551823,-!p1@ZNF443!0.66!6.13!ZNF443;;chr6:34204921..34204939,+!p3@HMGA1!0.65!123.65!HMGA1;;chr21:36260980..36261011,-!p1@RUNX1!0.65!118.54!RUNX1;;chr12:69753448..69753577,+!p1@YEATS4!0.65!80.73!YEATS4;;chr20:32274179..32274213,-!p1@E2F1!0.65!26.57!E2F1;;chr1:249132410..249132456,+!p1@ZNF672!0.64!29.64!ZNF672;;chr11:65686952..65686975,+!p5@DRAP1!0.64!21.46!DRAP1;;chr19:20188776..20188826,+!p1@ZNF90!0.64!10.22!ZNF90;;chr6:21597514..21597578,+!p4@SOX4!0.64!6.13!SOX4;;chr8:128752771..128752843,+!p9@MYC!0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|ffid_belonging_in_development=CL:0000134,CL:0000051
|fonse_cell_line=FF:0101035
|fonse_cell_line=FF:0101035
|fonse_cell_line_closure=FF:0101035
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Line 35: Line 41:
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Line 42: Line 60:
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Line 57: Line 78:
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Line 69: Line 91:
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lumen;1.8651732018972e-89!GO:0005739;mitochondrion;3.15135298225308e-87!GO:0043170;macromolecule metabolic process;3.15944093296213e-87!GO:0006396;RNA processing;1.12750187881302e-70!GO:0006412;translation;1.45457759972998e-64!GO:0043234;protein complex;3.18413357036347e-64!GO:0005840;ribosome;4.69016620852985e-64!GO:0044429;mitochondrial part;6.24146578959673e-60!GO:0003735;structural constituent of ribosome;1.57073995930061e-56!GO:0031981;nuclear lumen;4.90754956278314e-56!GO:0005515;protein binding;9.51997816930799e-55!GO:0044249;cellular biosynthetic process;9.82576534552362e-54!GO:0009058;biosynthetic process;3.53814737580151e-53!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;4.86312962741441e-52!GO:0016071;mRNA metabolic process;1.24079282418895e-51!GO:0043283;biopolymer metabolic process;2.61933847245674e-51!GO:0031967;organelle envelope;3.99846158845442e-50!GO:0006259;DNA metabolic process;4.81366877320145e-50!GO:0009059;macromolecule biosynthetic process;6.99185484573628e-50!GO:0031975;envelope;8.82760935091173e-50!GO:0033279;ribosomal subunit;4.67641481208042e-49!GO:0031090;organelle membrane;5.13875535895002e-47!GO:0010467;gene expression;1.50581485049984e-46!GO:0008380;RNA splicing;2.43204424869558e-46!GO:0019538;protein metabolic process;1.23130568538466e-45!GO:0006397;mRNA processing;2.88363719046797e-45!GO:0022613;ribonucleoprotein complex biogenesis and assembly;2.23594744523527e-43!GO:0044267;cellular protein metabolic process;3.42959917736517e-43!GO:0044260;cellular macromolecule metabolic process;1.64120118088333e-42!GO:0043228;non-membrane-bound organelle;3.42331430101479e-36!GO:0043232;intracellular non-membrane-bound organelle;3.42331430101479e-36!GO:0005829;cytosol;4.88547344930797e-36!GO:0016043;cellular component organization and biogenesis;7.79659475442544e-36!GO:0007049;cell cycle;8.92685627937031e-36!GO:0005740;mitochondrial envelope;1.03063231996914e-35!GO:0033036;macromolecule localization;2.05560522717864e-35!GO:0015031;protein transport;1.14080964599867e-34!GO:0005681;spliceosome;1.41970372574911e-34!GO:0006996;organelle organization and biogenesis;1.6727172105409e-34!GO:0019866;organelle inner membrane;1.93898475330473e-34!GO:0005654;nucleoplasm;6.92929081898957e-34!GO:0031966;mitochondrial membrane;2.19414722183363e-33!GO:0005830;cytosolic ribosome (sensu Eukaryota);2.8414045758221e-33!GO:0065003;macromolecular complex assembly;2.50165121541136e-32!GO:0005743;mitochondrial inner membrane;5.60535819835888e-32!GO:0045184;establishment of protein localization;7.43262529023386e-32!GO:0006974;response to DNA damage stimulus;1.25931217309516e-31!GO:0008104;protein localization;1.314134519374e-31!GO:0003676;nucleic acid binding;8.19485689784233e-31!GO:0006281;DNA repair;5.18797329225349e-30!GO:0044445;cytosolic part;1.21371757907035e-29!GO:0022402;cell cycle process;4.69709406961496e-29!GO:0000278;mitotic cell cycle;5.52407365758804e-29!GO:0005694;chromosome;1.21347209052186e-28!GO:0000166;nucleotide binding;1.64977875826458e-28!GO:0031980;mitochondrial lumen;2.66781757875034e-28!GO:0005759;mitochondrial matrix;2.66781757875034e-28!GO:0022607;cellular component assembly;1.33118628875231e-27!GO:0046907;intracellular transport;2.49944890133846e-27!GO:0006119;oxidative phosphorylation;1.66451593874282e-26!GO:0006886;intracellular protein transport;8.64366399552015e-26!GO:0044427;chromosomal part;9.97079966115786e-26!GO:0015934;large ribosomal subunit;1.25898226635592e-25!GO:0044451;nucleoplasm part;2.67394787221107e-25!GO:0022403;cell cycle phase;3.3989177408936e-25!GO:0000087;M phase of mitotic cell cycle;4.688132083242e-25!GO:0044455;mitochondrial membrane part;5.29137794367624e-25!GO:0015935;small ribosomal subunit;1.3293761573111e-24!GO:0007067;mitosis;1.68844000454018e-24!GO:0005730;nucleolus;2.11838034216405e-24!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;2.1260902567615e-23!GO:0016462;pyrophosphatase activity;2.4877549613249e-23!GO:0016817;hydrolase activity, acting on acid anhydrides;2.80610743314788e-23!GO:0017111;nucleoside-triphosphatase activity;7.89099946320793e-23!GO:0022618;protein-RNA complex assembly;1.69412181778822e-22!GO:0000279;M phase;6.1648966296164e-22!GO:0006260;DNA replication;6.96408539120827e-22!GO:0051301;cell division;7.02190929788234e-22!GO:0042254;ribosome biogenesis and assembly;2.37154388450521e-21!GO:0009719;response to endogenous stimulus;3.47257558776849e-21!GO:0016887;ATPase activity;9.63427475269771e-21!GO:0042623;ATPase activity, coupled;1.40826254820633e-20!GO:0005761;mitochondrial ribosome;2.73408173392238e-20!GO:0000313;organellar ribosome;2.73408173392238e-20!GO:0051276;chromosome organization and biogenesis;3.90229326892495e-20!GO:0032553;ribonucleotide binding;3.97166222180493e-20!GO:0032555;purine ribonucleotide binding;3.97166222180493e-20!GO:0017076;purine nucleotide binding;5.86505752117796e-20!GO:0005746;mitochondrial respiratory chain;8.28143792345812e-20!GO:0005524;ATP binding;8.70296382444649e-20!GO:0016874;ligase activity;8.80430324785772e-20!GO:0044265;cellular macromolecule catabolic process;1.5719013844416e-19!GO:0032559;adenyl ribonucleotide binding;2.38554843866493e-19!GO:0051649;establishment of cellular localization;3.49518813147433e-19!GO:0016070;RNA metabolic process;4.46490667515098e-19!GO:0030554;adenyl nucleotide binding;5.57599901692487e-19!GO:0051641;cellular localization;6.03507641891282e-19!GO:0051186;cofactor metabolic process;7.0173168726726e-19!GO:0006457;protein folding;2.11028560541839e-18!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;3.07904312892116e-18!GO:0008135;translation factor activity, nucleic acid binding;5.31849639304469e-18!GO:0006512;ubiquitin cycle;5.41168432144335e-18!GO:0012505;endomembrane system;5.91166304356593e-18!GO:0050136;NADH dehydrogenase (quinone) activity;1.15551615027369e-17!GO:0003954;NADH dehydrogenase activity;1.15551615027369e-17!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.15551615027369e-17!GO:0000502;proteasome complex (sensu Eukaryota);1.38922232833751e-17!GO:0000398;nuclear mRNA splicing, via spliceosome;2.99604346376861e-17!GO:0000375;RNA splicing, via transesterification reactions;2.99604346376861e-17!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;2.99604346376861e-17!GO:0044248;cellular catabolic process;6.06128902110176e-17!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);7.68378404267805e-17!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);9.36044150413592e-17!GO:0009057;macromolecule catabolic process;9.39393312862662e-17!GO:0042775;organelle ATP synthesis coupled electron transport;4.56629475322672e-16!GO:0042773;ATP synthesis coupled electron transport;4.56629475322672e-16!GO:0043285;biopolymer catabolic process;6.06286138707082e-16!GO:0031965;nuclear membrane;1.14425556209775e-15!GO:0030964;NADH dehydrogenase complex (quinone);1.4079460728533e-15!GO:0045271;respiratory chain complex I;1.4079460728533e-15!GO:0005747;mitochondrial respiratory chain complex I;1.4079460728533e-15!GO:0006732;coenzyme metabolic process;1.79624030418665e-15!GO:0016072;rRNA metabolic process;2.05616850905392e-15!GO:0006605;protein targeting;2.29048656517984e-15!GO:0044453;nuclear membrane part;2.29048656517984e-15!GO:0006364;rRNA processing;2.46904786733348e-15!GO:0005635;nuclear envelope;5.37216258552136e-15!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;5.52222829682893e-15!GO:0006399;tRNA metabolic process;1.07353161771562e-14!GO:0006325;establishment and/or maintenance of chromatin architecture;1.99538496264412e-14!GO:0006413;translational initiation;2.50518940580951e-14!GO:0051082;unfolded protein binding;2.88477378063715e-14!GO:0019941;modification-dependent protein catabolic process;3.25375209952297e-14!GO:0043632;modification-dependent macromolecule catabolic process;3.25375209952297e-14!GO:0051603;proteolysis involved in cellular protein catabolic process;3.26481399988872e-14!GO:0048770;pigment granule;3.54535317616412e-14!GO:0042470;melanosome;3.54535317616412e-14!GO:0006511;ubiquitin-dependent protein catabolic process;5.25476977134012e-14!GO:0003743;translation initiation factor activity;5.45849788316413e-14!GO:0044257;cellular protein catabolic process;5.57774023393355e-14!GO:0006323;DNA packaging;6.03775169175847e-14!GO:0051726;regulation of cell cycle;6.74927596024539e-14!GO:0000074;regulation of progression through cell cycle;7.82924728506467e-14!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;9.34343058983995e-14!GO:0016604;nuclear body;1.2143686321614e-13!GO:0009259;ribonucleotide metabolic process;1.4923427499253e-13!GO:0006163;purine nucleotide metabolic process;4.32582842418313e-13!GO:0005643;nuclear pore;4.89143696461236e-13!GO:0006261;DNA-dependent DNA replication;8.88853041370589e-13!GO:0004386;helicase activity;9.09564006094367e-13!GO:0006164;purine nucleotide biosynthetic process;1.14051303589193e-12!GO:0006446;regulation of translational initiation;1.29418866951179e-12!GO:0009260;ribonucleotide biosynthetic process;1.29418866951179e-12!GO:0008134;transcription factor binding;1.36756780510265e-12!GO:0043412;biopolymer modification;2.31997422252821e-12!GO:0044432;endoplasmic reticulum part;2.52547368508456e-12!GO:0009055;electron carrier activity;2.74713459011804e-12!GO:0000785;chromatin;4.92504730837252e-12!GO:0009150;purine ribonucleotide metabolic process;7.86754578561853e-12!GO:0065002;intracellular protein transport across a membrane;1.03744953128647e-11!GO:0043566;structure-specific DNA binding;1.1967015032367e-11!GO:0046930;pore complex;1.47170294945341e-11!GO:0008026;ATP-dependent helicase activity;1.62032911430547e-11!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.6338927940413e-11!GO:0030532;small nuclear ribonucleoprotein complex;1.89873413530875e-11!GO:0006403;RNA localization;1.89873413530875e-11!GO:0003697;single-stranded DNA binding;1.97523150349477e-11!GO:0009152;purine ribonucleotide biosynthetic process;2.09072258845698e-11!GO:0051188;cofactor biosynthetic process;2.41006489643936e-11!GO:0050657;nucleic acid transport;2.68829042665446e-11!GO:0051236;establishment of RNA localization;2.68829042665446e-11!GO:0050658;RNA transport;2.68829042665446e-11!GO:0030163;protein catabolic process;2.80716864591528e-11!GO:0016779;nucleotidyltransferase activity;3.28748055448127e-11!GO:0042175;nuclear envelope-endoplasmic reticulum network;3.76559525204626e-11!GO:0065004;protein-DNA complex assembly;4.1011958144107e-11!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;4.38737830332716e-11!GO:0019829;cation-transporting ATPase activity;4.4036058055341e-11!GO:0000775;chromosome, pericentric region;4.62048632324731e-11!GO:0006913;nucleocytoplasmic transport;1.00132739812791e-10!GO:0005789;endoplasmic reticulum membrane;1.14094088361866e-10!GO:0016568;chromatin modification;1.69832894976293e-10!GO:0051169;nuclear transport;2.24193739334481e-10!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;2.28040120421188e-10!GO:0006333;chromatin assembly or disassembly;3.78402927487789e-10!GO:0006464;protein modification process;3.96735545284018e-10!GO:0016607;nuclear speck;4.9339951636002e-10!GO:0005783;endoplasmic reticulum;8.01702404729646e-10!GO:0015986;ATP synthesis coupled proton transport;1.13602795284937e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.13602795284937e-09!GO:0009117;nucleotide metabolic process;1.46592583201963e-09!GO:0009060;aerobic respiration;1.73273861697146e-09!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.81480679660432e-09!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.95983215481963e-09!GO:0051028;mRNA transport;2.17572477881305e-09!GO:0012501;programmed cell death;2.7230109830417e-09!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;2.72847391485195e-09!GO:0004812;aminoacyl-tRNA ligase activity;2.72847391485195e-09!GO:0016875;ligase activity, forming carbon-oxygen bonds;2.72847391485195e-09!GO:0006915;apoptosis;3.01227274825159e-09!GO:0009056;catabolic process;3.32014913396343e-09!GO:0048193;Golgi vesicle transport;3.59123640963255e-09!GO:0016787;hydrolase activity;3.59123640963255e-09!GO:0005819;spindle;4.00162971036444e-09!GO:0009141;nucleoside triphosphate metabolic process;4.4669314330863e-09!GO:0009108;coenzyme biosynthetic process;4.843096071112e-09!GO:0009199;ribonucleoside triphosphate metabolic process;5.07298840388818e-09!GO:0017038;protein import;5.25080058185434e-09!GO:0006754;ATP biosynthetic process;5.57457747597349e-09!GO:0006753;nucleoside phosphate metabolic process;5.57457747597349e-09!GO:0015078;hydrogen ion transmembrane transporter activity;5.64295095749319e-09!GO:0046034;ATP metabolic process;6.88192627403347e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;6.95019904226848e-09!GO:0009142;nucleoside triphosphate biosynthetic process;6.95019904226848e-09!GO:0009201;ribonucleoside triphosphate biosynthetic process;6.95019904226848e-09!GO:0005839;proteasome core complex (sensu Eukaryota);7.37442781021849e-09!GO:0043687;post-translational protein modification;7.90788987988167e-09!GO:0045333;cellular respiration;9.18260951814669e-09!GO:0043038;amino acid activation;1.00246652628e-08!GO:0006418;tRNA aminoacylation for protein translation;1.00246652628e-08!GO:0043039;tRNA aminoacylation;1.00246652628e-08!GO:0007005;mitochondrion organization and biogenesis;1.17683615452442e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.21799977054804e-08!GO:0009144;purine nucleoside triphosphate metabolic process;1.21799977054804e-08!GO:0008639;small protein conjugating enzyme activity;1.34331244427221e-08!GO:0016740;transferase activity;1.38186536501911e-08!GO:0019787;small conjugating protein ligase activity;1.68524148060091e-08!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;1.75840448216544e-08!GO:0009145;purine nucleoside triphosphate biosynthetic process;1.75840448216544e-08!GO:0016469;proton-transporting two-sector ATPase complex;2.06889768283894e-08!GO:0005657;replication fork;2.27611047419643e-08!GO:0003899;DNA-directed RNA polymerase activity;2.4385269357463e-08!GO:0006084;acetyl-CoA metabolic process;2.75267584627006e-08!GO:0006099;tricarboxylic acid cycle;2.77760993782099e-08!GO:0046356;acetyl-CoA catabolic process;2.77760993782099e-08!GO:0008219;cell death;2.98915182392015e-08!GO:0016265;death;2.98915182392015e-08!GO:0004298;threonine endopeptidase activity;3.32422178205734e-08!GO:0004842;ubiquitin-protein ligase activity;3.68994783463717e-08!GO:0000075;cell cycle checkpoint;4.11693623530195e-08!GO:0006752;group transfer coenzyme metabolic process;4.48039738495972e-08!GO:0051325;interphase;6.73432696050727e-08!GO:0051329;interphase of mitotic cell cycle;7.27440583806186e-08!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;7.99225412493568e-08!GO:0015399;primary active transmembrane transporter activity;7.99225412493568e-08!GO:0008565;protein transporter activity;9.21776453856593e-08!GO:0005762;mitochondrial large ribosomal subunit;9.62033015756291e-08!GO:0000315;organellar large ribosomal subunit;9.62033015756291e-08!GO:0006302;double-strand break repair;1.09256152256835e-07!GO:0015077;monovalent inorganic cation transmembrane transporter activity;1.16365163960112e-07!GO:0006310;DNA recombination;1.58931351788643e-07!GO:0045259;proton-transporting ATP synthase complex;1.58940031870949e-07!GO:0008094;DNA-dependent ATPase activity;1.76287469735487e-07!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;1.83759208609733e-07!GO:0005813;centrosome;1.98741538102553e-07!GO:0000245;spliceosome assembly;2.11456631533641e-07!GO:0003712;transcription cofactor activity;2.39509059422026e-07!GO:0009109;coenzyme catabolic process;2.57251086188389e-07!GO:0005815;microtubule organizing center;3.0982717910332e-07!GO:0007051;spindle organization and biogenesis;3.20438410015111e-07!GO:0051246;regulation of protein metabolic process;3.41738013406279e-07!GO:0015630;microtubule cytoskeleton;4.83663199571182e-07!GO:0016881;acid-amino acid ligase activity;5.06759833816761e-07!GO:0016741;transferase activity, transferring one-carbon groups;5.06759833816761e-07!GO:0008033;tRNA processing;5.48695480861686e-07!GO:0008168;methyltransferase activity;6.57320933412142e-07!GO:0016491;oxidoreductase activity;6.97526799858456e-07!GO:0006334;nucleosome assembly;7.28452779838876e-07!GO:0051187;cofactor catabolic process;8.51968234342321e-07!GO:0031497;chromatin assembly;8.54810924345417e-07!GO:0006091;generation of precursor metabolites and energy;8.70916162719736e-07!GO:0009165;nucleotide biosynthetic process;9.07362426043437e-07!GO:0003690;double-stranded DNA binding;1.4024202897256e-06!GO:0006461;protein complex assembly;1.5168309466558e-06!GO:0032446;protein modification by small protein conjugation;1.52893317044733e-06!GO:0000314;organellar small ribosomal subunit;1.60002308994996e-06!GO:0005763;mitochondrial small ribosomal subunit;1.60002308994996e-06!GO:0004518;nuclease activity;1.74161585338917e-06!GO:0043492;ATPase activity, coupled to movement of substances;1.95598068109805e-06!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;2.04567556302104e-06!GO:0044452;nucleolar part;2.08181466399002e-06!GO:0003724;RNA helicase activity;2.10069405448393e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;2.5571772487192e-06!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;2.90552451773441e-06!GO:0007088;regulation of mitosis;3.14067566083939e-06!GO:0016567;protein ubiquitination;3.28691572395129e-06!GO:0006793;phosphorus metabolic process;5.19248643091383e-06!GO:0006796;phosphate metabolic process;5.19248643091383e-06!GO:0043681;protein import into mitochondrion;6.06847417718037e-06!GO:0006888;ER to Golgi vesicle-mediated transport;7.32838041074182e-06!GO:0043623;cellular protein complex assembly;7.57501848237314e-06!GO:0000151;ubiquitin ligase complex;7.82831194463358e-06!GO:0005667;transcription factor complex;8.14709316639714e-06!GO:0003684;damaged DNA binding;8.58098754611941e-06!GO:0005794;Golgi apparatus;1.10823095018093e-05!GO:0016310;phosphorylation;1.25220325098256e-05!GO:0051052;regulation of DNA metabolic process;1.448318206404e-05!GO:0016192;vesicle-mediated transport;1.49350011466034e-05!GO:0005793;ER-Golgi intermediate compartment;1.67196478710795e-05!GO:0006613;cotranslational protein targeting to membrane;1.7097208260272e-05!GO:0042981;regulation of apoptosis;2.05780111145641e-05!GO:0043021;ribonucleoprotein binding;2.08715885667721e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;2.5488190928162e-05!GO:0043067;regulation of programmed cell death;2.57622298306094e-05!GO:0003682;chromatin binding;2.62921837552281e-05!GO:0016853;isomerase activity;2.68444486527665e-05!GO:0006612;protein targeting to membrane;2.83049983941878e-05!GO:0000776;kinetochore;2.87888580354904e-05!GO:0015992;proton transport;3.44649834442229e-05!GO:0006401;RNA catabolic process;3.60014765715602e-05!GO:0007059;chromosome segregation;3.74464293580356e-05!GO:0006818;hydrogen transport;3.76659006553011e-05!GO:0006606;protein import into nucleus;3.98583636847124e-05!GO:0051170;nuclear import;4.528901228831e-05!GO:0006626;protein targeting to mitochondrion;4.80466317437905e-05!GO:0006383;transcription from RNA polymerase III promoter;4.82552190295167e-05!GO:0006352;transcription initiation;5.66567021641153e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;5.82535910023386e-05!GO:0005753;mitochondrial proton-transporting ATP synthase complex;6.41387645437851e-05!GO:0051168;nuclear export;6.5311880600375e-05!GO:0003678;DNA helicase activity;6.56766162280265e-05!GO:0000079;regulation of cyclin-dependent protein kinase activity;6.67836426201795e-05!GO:0004527;exonuclease activity;6.72900859033809e-05!GO:0065009;regulation of a molecular function;6.74311092272879e-05!GO:0016363;nuclear matrix;7.18289148311759e-05!GO:0008186;RNA-dependent ATPase activity;8.90842662221259e-05!GO:0003729;mRNA binding;8.96617057737143e-05!GO:0045454;cell redox homeostasis;9.9768933666885e-05!GO:0045786;negative regulation of progression through cell cycle;0.000117860604393599!GO:0007093;mitotic cell cycle checkpoint;0.000126756902608478!GO:0003713;transcription coactivator activity;0.000128526843018479!GO:0051540;metal cluster binding;0.000133037426658964!GO:0051536;iron-sulfur cluster binding;0.000133037426658964!GO:0007006;mitochondrial membrane organization and biogenesis;0.000145681901996972!GO:0009124;nucleoside monophosphate biosynthetic process;0.000149758293930274!GO:0009123;nucleoside monophosphate metabolic process;0.000149758293930274!GO:0006839;mitochondrial transport;0.000154486061604392!GO:0022890;inorganic cation transmembrane transporter activity;0.000171186917419472!GO:0006414;translational elongation;0.000175428062418447!GO:0051539;4 iron, 4 sulfur cluster binding;0.000183245749735697!GO:0008654;phospholipid biosynthetic process;0.000194080150791536!GO:0032508;DNA duplex unwinding;0.00019963638078327!GO:0032392;DNA geometric change;0.00019963638078327!GO:0006366;transcription from RNA polymerase II promoter;0.000199988979876316!GO:0006402;mRNA catabolic process;0.000209888709412028!GO:0006270;DNA replication initiation;0.00023158180967403!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000237071702303426!GO:0046483;heterocycle metabolic process;0.000242344514373467!GO:0005684;U2-dependent spliceosome;0.000259395564528877!GO:0004004;ATP-dependent RNA helicase activity;0.000264586947820443!GO:0005768;endosome;0.000264586947820443!GO:0016563;transcription activator activity;0.000280930682540744!GO:0006268;DNA unwinding during replication;0.000331951900017009!GO:0030880;RNA polymerase complex;0.000351443991291552!GO:0030120;vesicle coat;0.000353703211327749!GO:0030662;coated vesicle membrane;0.000353703211327749!GO:0006275;regulation of DNA replication;0.00038161647165409!GO:0004576;oligosaccharyl transferase activity;0.000401761768218198!GO:0051427;hormone receptor binding;0.000442237133712795!GO:0016251;general RNA polymerase II transcription factor activity;0.000443658678103874!GO:0009161;ribonucleoside monophosphate metabolic process;0.000467728759146292!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.000467728759146292!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000493163613086433!GO:0048475;coated membrane;0.000493470107553115!GO:0030117;membrane coat;0.000493470107553115!GO:0000228;nuclear chromosome;0.000495038917389289!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000495038917389289!GO:0019843;rRNA binding;0.000530253508323633!GO:0006007;glucose catabolic process;0.000541603303346954!GO:0019752;carboxylic acid metabolic process;0.000544814467611891!GO:0005885;Arp2/3 protein complex;0.000570336218515702!GO:0019899;enzyme binding;0.000575947555015564!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.000578575420888304!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.000578575420888304!GO:0019867;outer membrane;0.000592040715476266!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000594520707149573!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000594520707149573!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000594520707149573!GO:0006417;regulation of translation;0.00059862859868211!GO:0031968;organelle outer membrane;0.000598907668304517!GO:0043596;nuclear replication fork;0.000602406383064372!GO:0016272;prefoldin complex;0.000619153517320316!GO:0008250;oligosaccharyl transferase complex;0.000649717698274528!GO:0007052;mitotic spindle organization and biogenesis;0.000731460463013764!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000765792019426177!GO:0046474;glycerophospholipid biosynthetic process;0.000798042564328591!GO:0046489;phosphoinositide biosynthetic process;0.000821052464535686!GO:0000178;exosome (RNase complex);0.000857096748375094!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.000881705206332326!GO:0000428;DNA-directed RNA polymerase complex;0.000881705206332326!GO:0009112;nucleobase metabolic process;0.000882079919241158!GO:0035257;nuclear hormone receptor binding;0.00090069203129707!GO:0000786;nucleosome;0.00101225948025387!GO:0015631;tubulin binding;0.00102842636710401!GO:0006082;organic acid metabolic process;0.00106845295272229!GO:0016859;cis-trans isomerase activity;0.00109576176308865!GO:0051920;peroxiredoxin activity;0.00112528746638159!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00119979202472299!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.0012309247516273!GO:0032200;telomere organization and biogenesis;0.00148985758694249!GO:0000723;telomere maintenance;0.00148985758694249!GO:0050790;regulation of catalytic activity;0.00154120887652887!GO:0015980;energy derivation by oxidation of organic compounds;0.00157254945982595!GO:0009451;RNA modification;0.0015730449489946!GO:0031326;regulation of cellular biosynthetic process;0.0015954747475667!GO:0000049;tRNA binding;0.00163643685246161!GO:0006284;base-excision repair;0.00164188400143882!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00168992599093348!GO:0000070;mitotic sister chromatid segregation;0.0017000242713136!GO:0008408;3'-5' exonuclease activity;0.0017385198878635!GO:0043601;nuclear replisome;0.00181559820366707!GO:0030894;replisome;0.00181559820366707!GO:0005741;mitochondrial outer membrane;0.00186609385132042!GO:0006595;polyamine metabolic process;0.00194491199799924!GO:0005758;mitochondrial intermembrane space;0.00194583547524266!GO:0006650;glycerophospholipid metabolic process;0.00195451578179628!GO:0000725;recombinational repair;0.0020133877875337!GO:0000724;double-strand break repair via homologous recombination;0.0020133877875337!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00201466759982142!GO:0000082;G1/S transition of mitotic cell cycle;0.00202027820462931!GO:0030384;phosphoinositide metabolic process;0.00205590534148214!GO:0051252;regulation of RNA metabolic process;0.00206307588993855!GO:0000819;sister chromatid segregation;0.00206845378304233!GO:0008632;apoptotic program;0.00215312054667203!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00215757183903069!GO:0005637;nuclear inner membrane;0.00224569514615925!GO:0032259;methylation;0.00225582577792752!GO:0031124;mRNA 3'-end processing;0.00225582577792752!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00225582577792752!GO:0015002;heme-copper terminal oxidase activity;0.00225582577792752!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00225582577792752!GO:0004129;cytochrome-c oxidase activity;0.00225582577792752!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.00225808547747849!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00228494376689666!GO:0000287;magnesium ion binding;0.00228494376689666!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.00228494376689666!GO:0048500;signal recognition particle;0.00230203656945132!GO:0008312;7S RNA binding;0.00230639994386038!GO:0006118;electron transport;0.00234041972157734!GO:0000726;non-recombinational repair;0.00234206546287373!GO:0000059;protein import into nucleus, docking;0.00239678568053385!GO:0042393;histone binding;0.00249211920595281!GO:0006916;anti-apoptosis;0.00249641286700483!GO:0050662;coenzyme binding;0.00249751824136542!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.00251592423312267!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.00251592423312267!GO:0009126;purine nucleoside monophosphate metabolic process;0.00251592423312267!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.00251592423312267!GO:0000922;spindle pole;0.00253656012085002!GO:0046365;monosaccharide catabolic process;0.00254679413809844!GO:0005525;GTP binding;0.00258620055661763!GO:0047485;protein N-terminus binding;0.00270345904666811!GO:0031570;DNA integrity checkpoint;0.00273666941929558!GO:0018196;peptidyl-asparagine modification;0.00276183507294956!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00276183507294956!GO:0051053;negative regulation of DNA metabolic process;0.00289113131522337!GO:0019318;hexose metabolic process;0.00298250597668841!GO:0031072;heat shock protein binding;0.00343869455144456!GO:0005996;monosaccharide metabolic process;0.00349833158888106!GO:0006144;purine base metabolic process;0.00363267199393654!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.00369782455806394!GO:0006520;amino acid metabolic process;0.00374632205412873!GO:0006740;NADPH regeneration;0.00377523617531249!GO:0006098;pentose-phosphate shunt;0.00377523617531249!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00384564481903505!GO:0046164;alcohol catabolic process;0.00393339585772489!GO:0006405;RNA export from nucleus;0.00393529830329598!GO:0044262;cellular carbohydrate metabolic process;0.00401164485399503!GO:0006611;protein export from nucleus;0.00417500636160222!GO:0044450;microtubule organizing center part;0.00427318877106327!GO:0043414;biopolymer methylation;0.00431839782096419!GO:0044440;endosomal part;0.00437970042325782!GO:0010008;endosome membrane;0.00437970042325782!GO:0004003;ATP-dependent DNA helicase activity;0.00438196864788596!GO:0033116;ER-Golgi intermediate compartment membrane;0.0044247163128596!GO:0005669;transcription factor TFIID complex;0.00445519069913253!GO:0044431;Golgi apparatus part;0.00456818423428941!GO:0004532;exoribonuclease activity;0.00456940176794031!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00456940176794031!GO:0019320;hexose catabolic process;0.00462476880349612!GO:0000781;chromosome, telomeric region;0.00477170451495139!GO:0051320;S phase;0.00484784809621764!GO:0060090;molecular adaptor activity;0.0049499118693265!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00501093548153403!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00509628486321376!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.00526328534659043!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00532356904711509!GO:0045047;protein targeting to ER;0.00532356904711509!GO:0006506;GPI anchor biosynthetic process;0.00538486519156045!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00545255188971737!GO:0031970;organelle envelope lumen;0.00560300600920417!GO:0003711;transcription elongation regulator activity;0.00564430459160378!GO:0003746;translation elongation factor activity;0.00565859482592015!GO:0042802;identical protein binding;0.00578319490968505!GO:0050794;regulation of cellular process;0.00579902835157483!GO:0031123;RNA 3'-end processing;0.00579997416268347!GO:0009889;regulation of biosynthetic process;0.00582788977757275!GO:0009116;nucleoside metabolic process;0.00591203269662324!GO:0000792;heterochromatin;0.00603994493394748!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.00615467746184394!GO:0045039;protein import into mitochondrial inner membrane;0.00615467746184394!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.00622553798196541!GO:0031577;spindle checkpoint;0.006236225624234!GO:0042101;T cell receptor complex;0.00628597793050945!GO:0008139;nuclear localization sequence binding;0.00628597793050945!GO:0043488;regulation of mRNA stability;0.00651092455195494!GO:0043487;regulation of RNA stability;0.00651092455195494!GO:0005663;DNA replication factor C complex;0.00675866170769727!GO:0006505;GPI anchor metabolic process;0.00679952430334832!GO:0003887;DNA-directed DNA polymerase activity;0.00731752394796477!GO:0048523;negative regulation of cellular process;0.00732343954975987!GO:0006378;mRNA polyadenylation;0.00732343954975987!GO:0006006;glucose metabolic process;0.00743498471954817!GO:0044454;nuclear chromosome part;0.00754752515712257!GO:0031324;negative regulation of cellular metabolic process;0.00765043209904095!GO:0006950;response to stress;0.00780883535212716!GO:0051087;chaperone binding;0.00796487773027356!GO:0006096;glycolysis;0.00814781664125167!GO:0043022;ribosome binding;0.00814781664125167!GO:0006266;DNA ligation;0.00843113754527328!GO:0005876;spindle microtubule;0.0084508259720316!GO:0008180;signalosome;0.0084508259720316!GO:0008022;protein C-terminus binding;0.00862346687179109!GO:0016564;transcription repressor activity;0.00863924505765724!GO:0005869;dynactin complex;0.00867488485668186!GO:0016584;nucleosome positioning;0.00867488485668186!GO:0043069;negative regulation of programmed cell death;0.00868366360839407!GO:0005048;signal sequence binding;0.00880227218059638!GO:0008276;protein methyltransferase activity;0.00896234658423323!GO:0000139;Golgi membrane;0.00904863655104511!GO:0019222;regulation of metabolic process;0.00910382206850713!GO:0006779;porphyrin biosynthetic process;0.00926872938668459!GO:0033014;tetrapyrrole biosynthetic process;0.00926872938668459!GO:0008610;lipid biosynthetic process;0.0093366319658676!GO:0005832;chaperonin-containing T-complex;0.00950857328658937!GO:0000910;cytokinesis;0.00980291213505952!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00997902121097614!GO:0015036;disulfide oxidoreductase activity;0.0100179888765319!GO:0006338;chromatin remodeling;0.0102974839467452!GO:0051287;NAD binding;0.0104887497408662!GO:0046112;nucleobase biosynthetic process;0.0105618760296185!GO:0000339;RNA cap binding;0.0106307745773228!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0106307745773228!GO:0010257;NADH dehydrogenase complex assembly;0.0106307745773228!GO:0033108;mitochondrial respiratory chain complex assembly;0.0106307745773228!GO:0043066;negative regulation of apoptosis;0.0109512561533013!GO:0001772;immunological synapse;0.0109763987906321!GO:0006487;protein amino acid N-linked glycosylation;0.011015900171729!GO:0000077;DNA damage checkpoint;0.0111360730318434!GO:0008156;negative regulation of DNA replication;0.0112521872563802!GO:0048487;beta-tubulin binding;0.0112521872563802!GO:0004540;ribonuclease activity;0.0114050820430316!GO:0006891;intra-Golgi vesicle-mediated transport;0.0114764628146268!GO:0005770;late endosome;0.0117967278176394!GO:0043284;biopolymer biosynthetic process;0.0119051707228887!GO:0006400;tRNA modification;0.0119051707228887!GO:0016281;eukaryotic translation initiation factor 4F complex;0.0122195315677653!GO:0030262;apoptotic nuclear changes;0.0125708067067998!GO:0000175;3'-5'-exoribonuclease activity;0.0125813687331282!GO:0050852;T cell receptor signaling pathway;0.0129882722679951!GO:0009303;rRNA transcription;0.0130770096422619!GO:0006778;porphyrin metabolic process;0.0132945393942239!GO:0033013;tetrapyrrole metabolic process;0.0132945393942239!GO:0007050;cell cycle arrest;0.0135135395153606!GO:0016126;sterol biosynthetic process;0.0141719945559064!GO:0003924;GTPase activity;0.0142942546475211!GO:0035258;steroid hormone receptor binding;0.0145724725827667!GO:0043065;positive regulation of apoptosis;0.014790038023793!GO:0043189;H4/H2A histone acetyltransferase complex;0.0149195385479595!GO:0051789;response to protein stimulus;0.0149487310147057!GO:0006986;response to unfolded protein;0.0149487310147057!GO:0046467;membrane lipid biosynthetic process;0.0151814969341919!GO:0005769;early endosome;0.015247511451108!GO:0006730;one-carbon compound metabolic process;0.0154172961982936!GO:0000793;condensed chromosome;0.0154251126646216!GO:0008017;microtubule binding;0.0154473101932936!GO:0006289;nucleotide-excision repair;0.0154473101932936!GO:0022411;cellular component disassembly;0.0154505220025263!GO:0031988;membrane-bound vesicle;0.0157378340415352!GO:0032561;guanyl ribonucleotide binding;0.0158295594896051!GO:0019001;guanyl nucleotide binding;0.0158295594896051!GO:0007004;telomere maintenance via telomerase;0.0158295594896051!GO:0008538;proteasome activator activity;0.0159128683233629!GO:0051338;regulation of transferase activity;0.0159762455081842!GO:0033673;negative regulation of kinase activity;0.0159994417503188!GO:0006469;negative regulation of protein kinase activity;0.0159994417503188!GO:0006497;protein amino acid lipidation;0.0162953786323389!GO:0051348;negative regulation of transferase activity;0.0165122092749653!GO:0005798;Golgi-associated vesicle;0.0165356519750231!GO:0009892;negative regulation of metabolic process;0.0165455085924393!GO:0005732;small nucleolar ribonucleoprotein complex;0.0167184445659205!GO:0006066;alcohol metabolic process;0.0171006586172181!GO:0006519;amino acid and derivative metabolic process;0.0180300455749236!GO:0009081;branched chain family amino acid metabolic process;0.0183171278694977!GO:0005788;endoplasmic reticulum lumen;0.0186215130074217!GO:0035267;NuA4 histone acetyltransferase complex;0.0188183587026908!GO:0043068;positive regulation of programmed cell death;0.0188183587026908!GO:0004722;protein serine/threonine phosphatase activity;0.0188183587026908!GO:0006672;ceramide metabolic process;0.018848794265046!GO:0004448;isocitrate dehydrogenase activity;0.018848794265046!GO:0048519;negative regulation of biological process;0.0189652142690734!GO:0006303;double-strand break repair via nonhomologous end joining;0.0193175684621229!GO:0032404;mismatch repair complex binding;0.0196389805805562!GO:0048471;perinuclear region of cytoplasm;0.0197409423944043!GO:0007094;mitotic cell cycle spindle assembly checkpoint;0.0197409423944043!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0197409423944043!GO:0003714;transcription corepressor activity;0.0197409423944043!GO:0006376;mRNA splice site selection;0.0197572945028261!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0197572945028261!GO:0006695;cholesterol biosynthetic process;0.0199361913492023!GO:0031252;leading edge;0.0200116076222964!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0204419564430884!GO:0009396;folic acid and derivative biosynthetic process;0.0205918838231763!GO:0019900;kinase binding;0.0208349987585003!GO:0051235;maintenance of localization;0.0210056658269881!GO:0005652;nuclear lamina;0.0212107935689679!GO:0006767;water-soluble vitamin metabolic process;0.0220993212899365!GO:0019901;protein kinase binding;0.0220993212899365!GO:0006607;NLS-bearing substrate import into nucleus;0.0221945791934887!GO:0043549;regulation of kinase activity;0.0223542792987523!GO:0005070;SH3/SH2 adaptor activity;0.0226120214919463!GO:0000152;nuclear ubiquitin ligase complex;0.022750306836497!GO:0004523;ribonuclease H activity;0.0228499071357925!GO:0051881;regulation of mitochondrial membrane potential;0.0229814353774582!GO:0006301;postreplication repair;0.0229994394099415!GO:0044438;microbody part;0.0245395876903218!GO:0044439;peroxisomal part;0.0245395876903218!GO:0019206;nucleoside kinase activity;0.0246798851548028!GO:0033170;DNA-protein loading ATPase activity;0.0250603096920159!GO:0003689;DNA clamp loader activity;0.0250603096920159!GO:0032039;integrator complex;0.0253145473824063!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0256428948757001!GO:0030521;androgen receptor signaling pathway;0.0256428948757001!GO:0007040;lysosome organization and biogenesis;0.0256479470180382!GO:0008234;cysteine-type peptidase activity;0.0256642629888932!GO:0031982;vesicle;0.0256642629888932!GO:0045859;regulation of protein kinase activity;0.0273633321529667!GO:0006278;RNA-dependent DNA replication;0.027378450073625!GO:0005851;eukaryotic translation initiation factor 2B complex;0.0282076793734867!GO:0044275;cellular carbohydrate catabolic process;0.0282808756057307!GO:0022406;membrane docking;0.0285187609081054!GO:0048278;vesicle docking;0.0285187609081054!GO:0043631;RNA polyadenylation;0.0287148277966416!GO:0016023;cytoplasmic membrane-bound vesicle;0.0295486776089759!GO:0046982;protein heterodimerization activity;0.0297584122382905!GO:0004674;protein serine/threonine kinase activity;0.0297584122382905!GO:0008637;apoptotic mitochondrial changes;0.0297584122382905!GO:0006596;polyamine biosynthetic process;0.0301535013256687!GO:0030867;rough endoplasmic reticulum membrane;0.0303387398535632!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.030512346930024!GO:0006733;oxidoreduction coenzyme metabolic process;0.0311786528408099!GO:0008213;protein amino acid alkylation;0.031452858229676!GO:0006479;protein amino acid methylation;0.031452858229676!GO:0000123;histone acetyltransferase complex;0.0316436625180931!GO:0003725;double-stranded RNA binding;0.0319582399535626!GO:0030663;COPI coated vesicle membrane;0.0319813654831691!GO:0030126;COPI vesicle coat;0.0319813654831691!GO:0007021;tubulin folding;0.0328149004394977!GO:0005658;alpha DNA polymerase:primase complex;0.0328149004394977!GO:0001522;pseudouridine synthesis;0.0328149004394977!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0328149004394977!GO:0030176;integral to endoplasmic reticulum membrane;0.0329332389021482!GO:0004519;endonuclease activity;0.0330175606934298!GO:0030508;thiol-disulfide exchange intermediate activity;0.033715451666393!GO:0033261;regulation of progression through S phase;0.0340485903892696!GO:0006904;vesicle docking during exocytosis;0.03445859673476!GO:0048037;cofactor binding;0.0349385539881685!GO:0006783;heme biosynthetic process;0.0351428812421029!GO:0031903;microbody membrane;0.0353678271064291!GO:0005778;peroxisomal membrane;0.0353678271064291!GO:0000096;sulfur amino acid metabolic process;0.0353678271064291!GO:0006635;fatty acid beta-oxidation;0.0353678271064291!GO:0007033;vacuole organization and biogenesis;0.0353938256561576!GO:0031647;regulation of protein stability;0.0356195851311693!GO:0042158;lipoprotein biosynthetic process;0.0360087679928964!GO:0042769;DNA damage response, detection of DNA damage;0.0366691842467934!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0367063058555861!GO:0007346;regulation of progression through mitotic cell cycle;0.037551429997324!GO:0000080;G1 phase of mitotic cell cycle;0.0378308521553779!GO:0005521;lamin binding;0.0393114177899282!GO:0032405;MutLalpha complex binding;0.0395668931877179!GO:0005784;translocon complex;0.0399486528835497!GO:0001824;blastocyst development;0.0400119677007529!GO:0046128;purine ribonucleoside metabolic process;0.0400119677007529!GO:0042278;purine nucleoside metabolic process;0.0400119677007529!GO:0009262;deoxyribonucleotide metabolic process;0.0400119677007529!GO:0008144;drug binding;0.0400847354334193!GO:0005777;peroxisome;0.0401623543065073!GO:0042579;microbody;0.0401623543065073!GO:0030677;ribonuclease P complex;0.0404254886427391!GO:0017134;fibroblast growth factor binding;0.0405473635194605!GO:0046519;sphingoid metabolic process;0.0405836345736677!GO:0005773;vacuole;0.0412995985223623!GO:0005092;GDP-dissociation inhibitor activity;0.0418057100129932!GO:0016569;covalent chromatin modification;0.0419519805182718!GO:0019238;cyclohydrolase activity;0.0419519805182718!GO:0030261;chromosome condensation;0.0421587833730704!GO:0009083;branched chain family amino acid catabolic process;0.0421950997253039!GO:0000118;histone deacetylase complex;0.0422126985125398!GO:0007017;microtubule-based process;0.0423014466612124!GO:0008625;induction of apoptosis via death domain receptors;0.042722381955653!GO:0050178;phenylpyruvate tautomerase activity;0.0429068734302039!GO:0051452;cellular pH reduction;0.0429068734302039!GO:0051453;regulation of cellular pH;0.0429068734302039!GO:0045851;pH reduction;0.0429068734302039!GO:0008287;protein serine/threonine phosphatase complex;0.042980839831623!GO:0051297;centrosome organization and biogenesis;0.0432829019563621!GO:0031023;microtubule organizing center organization and biogenesis;0.0432829019563621!GO:0042608;T cell receptor binding;0.0435145552413447!GO:0030658;transport vesicle membrane;0.0438921350594145!GO:0008537;proteasome activator complex;0.0448676335040178!GO:0000084;S phase of mitotic cell cycle;0.0455630653964692!GO:0030174;regulation of DNA replication initiation;0.045576160662499!GO:0008652;amino acid biosynthetic process;0.0456547332767781!GO:0042168;heme metabolic process;0.0459594501604209!GO:0040029;regulation of gene expression, epigenetic;0.0459594501604209!GO:0017069;snRNA binding;0.0461106394468805!GO:0008320;protein transmembrane transporter activity;0.0462506815215774!GO:0006917;induction of apoptosis;0.0465883080727132!GO:0030137;COPI-coated vesicle;0.0472045471197568!GO:0003893;epsilon DNA polymerase activity;0.0476237386497621!GO:0016407;acetyltransferase activity;0.047959303477004!GO:0022884;macromolecule transmembrane transporter activity;0.0486724712839852!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0486724712839852!GO:0005686;snRNP U2;0.0491279927662523!GO:0005689;U12-dependent spliceosome;0.0494639379306061!GO:0008143;poly(A) binding;0.0499154164265611!GO:0008097;5S rRNA binding;0.0499368552495282!GO:0046426;negative regulation of JAK-STAT cascade;0.0499694138291617!GO:0000387;spliceosomal snRNP biogenesis;0.0499777429617761
|sample_id=10416
|sample_id=10416
|sample_note=
|sample_note=
Line 76: Line 99:
|sample_tissue=blood
|sample_tissue=blood
|top_motifs=E2F1..5:2.18656627694;NR5A1,2:2.05440719568;MYB:1.91786819862;IKZF2:1.63702527573;ARID5B:1.43342916442;POU3F1..4:1.40568950014;AIRE:1.39721679203;YY1:1.3926356171;DMAP1_NCOR{1,2}_SMARC:1.37024124685;T:1.2475298909;POU6F1:1.19605429116;PAX6:1.108809533;HOXA9_MEIS1:1.10668285571;NFY{A,B,C}:1.1063863711;ELF1,2,4:1.08301414533;POU2F1..3:1.07519852031;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.04365575483;GATA6:1.04194235123;RUNX1..3:1.0206255079;CDX1,2,4:1.00064056931;SPZ1:0.964373234292;ZBTB16:0.910309451829;GFI1:0.885624218328;PBX1:0.870717813437;ZNF143:0.83932535285;RORA:0.774736693632;SNAI1..3:0.759536757479;NRF1:0.720343663789;SPI1:0.663553746771;HES1:0.660016224213;TLX2:0.648055281235;BREu{core}:0.647131986928;TFDP1:0.588051567877;FOXA2:0.564684921103;FOXP3:0.551173125945;STAT5{A,B}:0.523475151704;LMO2:0.499531684781;ESRRA:0.485803227728;SPIB:0.483104154886;ETS1,2:0.480498799223;ELK1,4_GABP{A,B1}:0.479526012782;TEF:0.442607225238;MYOD1:0.414864744763;SOX{8,9,10}:0.410525150371;ZNF148:0.400884465443;ONECUT1,2:0.393748581701;CDC5L:0.360231253434;PITX1..3:0.341147386046;RBPJ:0.33438749151;UFEwm:0.309411865147;NANOG:0.280726796911;NKX6-1,2:0.273455050846;bHLH_family:0.231505232085;ZEB1:0.212169031222;EVI1:0.162774590865;POU1F1:0.15294120578;NKX3-1:0.151724674599;FOXD3:0.150084621608;HAND1,2:0.130837698016;PAX8:0.112377881167;FOXP1:0.111475667478;BPTF:0.103309442862;RFX2..5_RFXANK_RFXAP:0.0804964736763;TGIF1:0.0752688041258;NFE2L1:0.0732660539716;NANOG{mouse}:0.0588092432905;ALX1:0.0572066932118;HOX{A6,A7,B6,B7}:-0.032297544846;NKX2-2,8:-0.0479295963529;PDX1:-0.0753106366731;FOXM1:-0.0758664601767;IRF1,2:-0.0908234178193;CUX2:-0.091015213607;NKX2-1,4:-0.0957446431547;HNF4A_NR2F1,2:-0.121062930993;IRF7:-0.121063387702;KLF4:-0.12234595867;FOX{F1,F2,J1}:-0.126724399567;VSX1,2:-0.153310960424;HSF1,2:-0.17895238759;PAX4:-0.185771730497;LHX3,4:-0.195403363324;AR:-0.198221618408;RXRA_VDR{dimer}:-0.208105641487;OCT4_SOX2{dimer}:-0.227367081886;EN1,2:-0.254980357812;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.258733932935;HOX{A4,D4}:-0.288395528577;FOX{I1,J2}:-0.307220390676;HNF1A:-0.309303315257;LEF1_TCF7_TCF7L1,2:-0.309754936998;NFKB1_REL_RELA:-0.315951928744;ATF5_CREB3:-0.325239700403;HOX{A5,B5}:-0.32634695662;NR3C1:-0.363120276398;GZF1:-0.365915535975;TAL1_TCF{3,4,12}:-0.373790741703;SOX17:-0.374523742791;SOX5:-0.385358121549;NFIL3:-0.446367414505;RFX1:-0.453428180841;FOXO1,3,4:-0.465394658905;MYFfamily:-0.477760146537;PAX5:-0.479123472022;MEF2{A,B,C,D}:-0.48379998039;PRRX1,2:-0.486154022691;PAX2:-0.486285296261;PPARG:-0.491909576351;CRX:-0.496330401125;GFI1B:-0.519208963331;HBP1_HMGB_SSRP1_UBTF:-0.532539397364;ZNF423:-0.536112553461;CEBPA,B_DDIT3:-0.555801043885;GATA4:-0.586615240695;NKX2-3_NKX2-5:-0.588828158625;NFE2L2:-0.626259385206;ZIC1..3:-0.626376462794;ZNF384:-0.632549697256;PAX3,7:-0.635727894912;NFE2:-0.645436029192;NR1H4:-0.664505266105;SOX2:-0.676307474469;DBP:-0.690655013049;MYBL2:-0.707153692411;NR6A1:-0.712981782286;ZBTB6:-0.719062929714;FOS_FOS{B,L1}_JUN{B,D}:-0.724618897329;SMAD1..7,9:-0.72604773704;HMX1:-0.75056246749;PAX1,9:-0.758914730259;TFAP4:-0.76473448344;NFIX:-0.768956498855;ZNF238:-0.771951692503;POU5F1:-0.784672392001;REST:-0.785102829238;STAT1,3:-0.809538946549;HLF:-0.823521140812;FOXN1:-0.83571771984;BACH2:-0.83938648594;TBP:-0.843638777033;NHLH1,2:-0.869362090275;FOSL2:-0.870363942483;CREB1:-0.877003662766;FOXQ1:-0.881854333622;EBF1:-0.883954558964;GTF2A1,2:-0.940476114734;RXR{A,B,G}:-0.966814504907;GCM1,2:-0.971239031375;MTF1:-0.980084800607;STAT2,4,6:-0.999787513861;NKX3-2:-1.00664103826;JUN:-1.01757400107;AHR_ARNT_ARNT2:-1.05457521726;MED-1{core}:-1.0608999852;PRDM1:-1.06654814473;ATF4:-1.07169848517;ALX4:-1.08938188915;RREB1:-1.09781870164;TOPORS:-1.0997369855;SREBF1,2:-1.12485537268;TP53:-1.12588396843;NFATC1..3:-1.15208772956;ATF6:-1.18598515883;IKZF1:-1.18811335413;TBX4,5:-1.19216302613;SRF:-1.21000503094;HIF1A:-1.23064606546;ESR1:-1.23774402903;FOXL1:-1.25891612764;MZF1:-1.28311567617;MTE{core}:-1.33696863584;ZFP161:-1.39485914215;GTF2I:-1.42980073787;TEAD1:-1.47873305437;ADNP_IRX_SIX_ZHX:-1.4818855424;HMGA1,2:-1.57195577734;EP300:-1.58209677858;XBP1:-1.65866128396;HIC1:-1.71821530907;FOX{D1,D2}:-1.74135401747;GLI1..3:-1.75150060856;TFAP2B:-1.79120171203;TLX1..3_NFIC{dimer}:-1.7967534544;MAZ:-1.81115452799;ATF2:-1.86762551307;PATZ1:-1.98150667199;TFCP2:-2.15345661856;MAFB:-2.1600979744;EGR1..3:-2.2940773233;XCPE1{core}:-2.39954428826;TFAP2{A,C}:-2.4948043587;SP1:-2.51744175804
|top_motifs=E2F1..5:2.18656627694;NR5A1,2:2.05440719568;MYB:1.91786819862;IKZF2:1.63702527573;ARID5B:1.43342916442;POU3F1..4:1.40568950014;AIRE:1.39721679203;YY1:1.3926356171;DMAP1_NCOR{1,2}_SMARC:1.37024124685;T:1.2475298909;POU6F1:1.19605429116;PAX6:1.108809533;HOXA9_MEIS1:1.10668285571;NFY{A,B,C}:1.1063863711;ELF1,2,4:1.08301414533;POU2F1..3:1.07519852031;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.04365575483;GATA6:1.04194235123;RUNX1..3:1.0206255079;CDX1,2,4:1.00064056931;SPZ1:0.964373234292;ZBTB16:0.910309451829;GFI1:0.885624218328;PBX1:0.870717813437;ZNF143:0.83932535285;RORA:0.774736693632;SNAI1..3:0.759536757479;NRF1:0.720343663789;SPI1:0.663553746771;HES1:0.660016224213;TLX2:0.648055281235;BREu{core}:0.647131986928;TFDP1:0.588051567877;FOXA2:0.564684921103;FOXP3:0.551173125945;STAT5{A,B}:0.523475151704;LMO2:0.499531684781;ESRRA:0.485803227728;SPIB:0.483104154886;ETS1,2:0.480498799223;ELK1,4_GABP{A,B1}:0.479526012782;TEF:0.442607225238;MYOD1:0.414864744763;SOX{8,9,10}:0.410525150371;ZNF148:0.400884465443;ONECUT1,2:0.393748581701;CDC5L:0.360231253434;PITX1..3:0.341147386046;RBPJ:0.33438749151;UFEwm:0.309411865147;NANOG:0.280726796911;NKX6-1,2:0.273455050846;bHLH_family:0.231505232085;ZEB1:0.212169031222;EVI1:0.162774590865;POU1F1:0.15294120578;NKX3-1:0.151724674599;FOXD3:0.150084621608;HAND1,2:0.130837698016;PAX8:0.112377881167;FOXP1:0.111475667478;BPTF:0.103309442862;RFX2..5_RFXANK_RFXAP:0.0804964736763;TGIF1:0.0752688041258;NFE2L1:0.0732660539716;NANOG{mouse}:0.0588092432905;ALX1:0.0572066932118;HOX{A6,A7,B6,B7}:-0.032297544846;NKX2-2,8:-0.0479295963529;PDX1:-0.0753106366731;FOXM1:-0.0758664601767;IRF1,2:-0.0908234178193;CUX2:-0.091015213607;NKX2-1,4:-0.0957446431547;HNF4A_NR2F1,2:-0.121062930993;IRF7:-0.121063387702;KLF4:-0.12234595867;FOX{F1,F2,J1}:-0.126724399567;VSX1,2:-0.153310960424;HSF1,2:-0.17895238759;PAX4:-0.185771730497;LHX3,4:-0.195403363324;AR:-0.198221618408;RXRA_VDR{dimer}:-0.208105641487;OCT4_SOX2{dimer}:-0.227367081886;EN1,2:-0.254980357812;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.258733932935;HOX{A4,D4}:-0.288395528577;FOX{I1,J2}:-0.307220390676;HNF1A:-0.309303315257;LEF1_TCF7_TCF7L1,2:-0.309754936998;NFKB1_REL_RELA:-0.315951928744;ATF5_CREB3:-0.325239700403;HOX{A5,B5}:-0.32634695662;NR3C1:-0.363120276398;GZF1:-0.365915535975;TAL1_TCF{3,4,12}:-0.373790741703;SOX17:-0.374523742791;SOX5:-0.385358121549;NFIL3:-0.446367414505;RFX1:-0.453428180841;FOXO1,3,4:-0.465394658905;MYFfamily:-0.477760146537;PAX5:-0.479123472022;MEF2{A,B,C,D}:-0.48379998039;PRRX1,2:-0.486154022691;PAX2:-0.486285296261;PPARG:-0.491909576351;CRX:-0.496330401125;GFI1B:-0.519208963331;HBP1_HMGB_SSRP1_UBTF:-0.532539397364;ZNF423:-0.536112553461;CEBPA,B_DDIT3:-0.555801043885;GATA4:-0.586615240695;NKX2-3_NKX2-5:-0.588828158625;NFE2L2:-0.626259385206;ZIC1..3:-0.626376462794;ZNF384:-0.632549697256;PAX3,7:-0.635727894912;NFE2:-0.645436029192;NR1H4:-0.664505266105;SOX2:-0.676307474469;DBP:-0.690655013049;MYBL2:-0.707153692411;NR6A1:-0.712981782286;ZBTB6:-0.719062929714;FOS_FOS{B,L1}_JUN{B,D}:-0.724618897329;SMAD1..7,9:-0.72604773704;HMX1:-0.75056246749;PAX1,9:-0.758914730259;TFAP4:-0.76473448344;NFIX:-0.768956498855;ZNF238:-0.771951692503;POU5F1:-0.784672392001;REST:-0.785102829238;STAT1,3:-0.809538946549;HLF:-0.823521140812;FOXN1:-0.83571771984;BACH2:-0.83938648594;TBP:-0.843638777033;NHLH1,2:-0.869362090275;FOSL2:-0.870363942483;CREB1:-0.877003662766;FOXQ1:-0.881854333622;EBF1:-0.883954558964;GTF2A1,2:-0.940476114734;RXR{A,B,G}:-0.966814504907;GCM1,2:-0.971239031375;MTF1:-0.980084800607;STAT2,4,6:-0.999787513861;NKX3-2:-1.00664103826;JUN:-1.01757400107;AHR_ARNT_ARNT2:-1.05457521726;MED-1{core}:-1.0608999852;PRDM1:-1.06654814473;ATF4:-1.07169848517;ALX4:-1.08938188915;RREB1:-1.09781870164;TOPORS:-1.0997369855;SREBF1,2:-1.12485537268;TP53:-1.12588396843;NFATC1..3:-1.15208772956;ATF6:-1.18598515883;IKZF1:-1.18811335413;TBX4,5:-1.19216302613;SRF:-1.21000503094;HIF1A:-1.23064606546;ESR1:-1.23774402903;FOXL1:-1.25891612764;MZF1:-1.28311567617;MTE{core}:-1.33696863584;ZFP161:-1.39485914215;GTF2I:-1.42980073787;TEAD1:-1.47873305437;ADNP_IRX_SIX_ZHX:-1.4818855424;HMGA1,2:-1.57195577734;EP300:-1.58209677858;XBP1:-1.65866128396;HIC1:-1.71821530907;FOX{D1,D2}:-1.74135401747;GLI1..3:-1.75150060856;TFAP2B:-1.79120171203;TLX1..3_NFIC{dimer}:-1.7967534544;MAZ:-1.81115452799;ATF2:-1.86762551307;PATZ1:-1.98150667199;TFCP2:-2.15345661856;MAFB:-2.1600979744;EGR1..3:-2.2940773233;XCPE1{core}:-2.39954428826;TFAP2{A,C}:-2.4948043587;SP1:-2.51744175804
|xref=
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10416-106C2;search_select_hide=table117:FF:10416-106C2
}}
}}

Latest revision as of 14:00, 3 June 2020

Name:chronic lymphocytic leukemia (T-CLL) cell line:SKW-3
Species:Human (Homo sapiens)
Library ID:CNhs11714
Sample type:cell lines
Genomic View: UCSC
RefEX:Specific genes
CAGEd-oPOSSUM:link
ZENBU report :link
Additional information
Sample information
strainNA
tissueblood
dev stage27 year old adult
sexmale
age27
cell typet cell
cell lineSKW-3
companyRIKEN Bioresource centre
collaborationYukio Nakamura (RIKEN BRC)
External link for information[{{{sample_info_link}}} {{{sample_info_link}}}]
RNA information
lot numberNA
catalog numberNA
sample typetotal RNA
extraction protocol (Details)OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0

CAGE Accession numbers
MethodSample accession id
CAGE  SAMD00006003
Library accession numbers

Library idMethodExp. accession idRun accession id
CNhs11714 CAGE DRX007852 DRR008724
Accession ID Hg19

Library idBAMCTSS
CNhs11714 DRZ000149 DRZ001534
Accession ID Hg38

Library idBAMCTSS
CNhs11714 DRZ011499 DRZ012884
Download raw sequence, BAM & CTSS
Hg19
FastaBAMCTSS
downloaddownloaddonwload
Hg38
BAMCTSS
downloaddonwload


Relative expression to median (log10)

Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.



Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data

Coexpression clusterscore
C0-CD14-Eosinophils-Neutrophils-Basophils-CD34-immature-Peripheral0
C1-testis-epididymis-embryonic-medulla-pituitary-trachea-caudate0
C10-occipital-temporal-parietal-brain-duodenum-Neurons-Neural0
C100-rhabdomyosarcoma-gastric-pineal-Wilms-cervical-mesodermal-endometrial0
C101-small-cerebellum-maxillary-colon-parietal-epididymis-merkel0
C102-neuroblastoma-testicular-pituitary-carcinosarcoma-rectum-acantholytic-iPS0
C103-CD4-CD8-Natural-Peripheral-Whole-Neutrophils-Basophils0
C104-Mast-Basophils-immature-CD14-CD34-eye-Natural0
C105-heart-skeletal-occipital-hippocampus-acute-Sebocyte-penis0.066
C106-Hep2-epitheloid-placenta-cervical-rectal-anaplastic-glassy0
C107-Neutrophils-CD14-Eosinophils-Monocytederived-Whole-Peripheral-blood0
C108-breast-hepatoblastoma-MCF7-parotid-salivary-submaxillary-prostate0
C109-Reticulocytes-non-acute-Hodgkin-Burkitt-retinoblastoma-lymphoma0.658
C11-cerebellum-medulla-pons-parietal-occipital-middle-medial0
C110-leukemia-chronic-Eosinophils-acute-Whole-CD34-Lymphatic0
C111-medulla-lung-trachea-testis-caudate-epididymis-throat0
C112-gastric-pancreas-temporal-duodenum-small-extraskeletal-adrenal0
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C96-non-acute-tonsil-spleen-Burkitt-lymphoma-appendix0
C97-small-smallcell-gastrointestinal-argyrophil-putamen-duodenum-brain0
C98-CD8-Natural-Basophils-blood-CD4-Peripheral-Whole0
C99-hairy-mycosis-submaxillary-salivary-cord-kidney-parotid0



Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data



TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample

JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs11714

Jaspar motifP-value
MA0002.29.59318e-4
MA0003.10.982
MA0004.10.395
MA0006.10.493
MA0007.10.667
MA0009.10.9
MA0014.10.691
MA0017.10.114
MA0018.29.84657e-4
MA0019.10.192
MA0024.12.82884e-7
MA0025.10.32
MA0027.10.399
MA0028.10.00979
MA0029.10.687
MA0030.10.0071
MA0031.10.138
MA0035.25.0818e-4
MA0038.10.783
MA0039.20.312
MA0040.10.142
MA0041.10.113
MA0042.10.265
MA0043.10.00187
MA0046.10.0342
MA0047.20.595
MA0048.10.956
MA0050.10.756
MA0051.10.756
MA0052.10.0285
MA0055.10.509
MA0057.10.747
MA0058.10.506
MA0059.10.00354
MA0060.17.88823e-4
MA0061.10.564
MA0062.22.9811e-5
MA0065.20.00788
MA0066.10.132
MA0067.10.04
MA0068.10.432
MA0069.10.472
MA0070.10.868
MA0071.10.188
MA0072.10.28
MA0073.10.766
MA0074.10.901
MA0076.10.00146
MA0077.10.541
MA0078.10.759
MA0079.20.177
MA0080.27.95428e-4
MA0081.10.133
MA0083.17.1531e-5
MA0084.10.969
MA0087.10.285
MA0088.10.00757
MA0090.14.06942e-4
MA0091.10.342
MA0092.10.375
MA0093.10.485
MA0099.22.37246e-6
MA0100.10.0181
MA0101.10.167
MA0102.20.0191
MA0103.10.0196
MA0104.20.00228
MA0105.10.00313
MA0106.10.352
MA0107.10.0457
MA0108.21.55921e-8
MA0111.10.188
MA0112.20.0523
MA0113.10.902
MA0114.10.124
MA0115.10.18
MA0116.15.63041e-5
MA0117.10.686
MA0119.10.445
MA0122.10.879
MA0124.10.369
MA0125.10.364
MA0131.10.403
MA0135.10.0883
MA0136.18.9519e-5
MA0137.20.0217
MA0138.20.702
MA0139.10.172
MA0140.14.67122e-4
MA0141.10.0637
MA0142.10.623
MA0143.10.375
MA0144.10.187
MA0145.10.574
MA0146.10.73
MA0147.13.32843e-4
MA0148.10.357
MA0149.10.0351
MA0150.10.499
MA0152.10.278
MA0153.10.0422
MA0154.10.0294
MA0155.10.948
MA0156.16.38343e-5
MA0157.10.95
MA0159.10.0973
MA0160.10.381
MA0162.10.454
MA0163.12.19565e-14
MA0164.10.864
MA0258.10.0439
MA0259.10.0504



FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs11714

Novel motifP-value
10.0365
100.0182
1000.25
1010.499
1020.467
1030.056
1040.442
1050.946
1060.844
1070.853
1080.837
1090.0164
110.0369
1100.222
1110.108
1120.515
1130.803
1140.0892
1150.196
1160.231
1170.0281
1180.982
1190.318
120.597
1200.246
1210.458
1220.769
1230.0215
1240.0779
1250.00422
1260.618
1270.363
1280.756
1290.226
130.126
1300.235
1310.654
1320.813
1330.203
1340.483
1350.885
1360.547
1370.942
1380.429
1390.308
140.874
1400.181
1410.101
1420.219
1433.53499e-5
1440.934
1450.317
1460.432
1470.503
1480.281
1490.497
150.0885
1500.558
1510.964
1520.0506
1530.882
1540.754
1550.109
1560.874
1570.237
1580.969
1590.205
160.36
1600.0747
1610.0901
1620.979
1630.397
1640.208
1650.431
1660.957
1670.0501
1680.821
1690.84
170.74
180.551
190.964
20.95
200.79
210.107
220.81
230.378
240.305
250.17
260.0222
270.248
280.861
290.00763
30.211
300.326
310.835
320.35
330.485
340.587
350.0857
360.0204
370.4
380.499
390.735
40.226
400.228
410.444
420.18
430.249
440.0807
450.508
460.0672
470.00606
480.071
490.0597
50.322
500.759
510.732
520.193
530.676
540.688
550.912
560.653
570.332
580.266
590.499
60.446
600.973
610.393
620.108
630.344
640.116
650.631
660.0252
670.715
680.534
690.37
70.223
700.218
710.00993
720.934
730.691
740.284
750.0196
760.389
770.77
780.243
790.478
80.104
800.33
810.196
820.372
830.646
840.958
850.743
860.487
870.271
880.689
890.232
90.954
900.135
910.983
920.714
930.107
940.172
950.124
960.0839
970.36
980.224
990.561



de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br> library id: CNhs11714


FANTOM5 (FF) ontology

Direct parent terms


Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data

CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0002371 (somatic cell)
0000542 (lymphocyte)
0000219 (motile cell)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0002242 (nucleate cell)
0000255 (eukaryotic cell)
0000084 (T cell)

DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
1240 (leukemia)
1036 (chronic leukemia)

FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100737 (leukemia cell line sample)
0101035 (hematopoietic cell line sample)
0103505 (T-cell chronic lymphocytic leukemia cell sample)

Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000051 (common lymphoid progenitor)

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