FF:11920-125H3: Difference between revisions
From FANTOM5_SSTAR
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00004761 | ||
| | |accession_numbers=CAGE;DRX008183;DRR009055;DRZ000480;DRZ001865;DRZ011830;DRZ013215 | ||
| | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003 | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001 | ||
|comment=Changed from previous label. TODO: full classification | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chrX:49121165..49121179,-!p1@FOXP3!2.60!397.72!FOXP3;;chr10:8096631..8096660,+!p1@GATA3!1.89!91.43!GATA3;;chr14:75988831..75988847,+!p2@BATF!1.88!74.78!BATF;;chr17:37934204..37934241,-!p3@IKZF3!1.84!68.93!IKZF3;;chr16:79634624..79634642,-!p1@MAF!1.83!248.02!MAF;;chr10:8096772..8096787,+!p2@GATA3!1.83!78.30!GATA3;;chr17:37934365..37934387,-!p2@IKZF3!1.82!65.68!IKZF3;;chr7:50343634..50343717,+!p2@IKZF1!1.81!63.86!IKZF1;;chr16:79634595..79634620,-!p2@MAF!1.78!105.22!MAF;;chr14:75988771..75988826,+!p1@BATF!1.77!75.30!BATF;;chr2:231090433..231090469,+!p1@SP140!1.65!43.18!SP140;;chr1:25256756..25256774,-!p1@RUNX3!1.53!59.83!RUNX3;;chr19:19779619..19779670,+!p1@ZNF101!1.51!86.10!ZNF101;;chr20:50159198..50159299,-!p1@NFATC2!1.47!40.71!NFATC2;;chr20:56195474..56195506,-!p1@ZBP1!1.47!28.35!ZBP1;;chr3:18486354..18486377,-!p2@SATB1!1.46!34.86!SATB1;;chrY:21906594..21906622,-!p1@KDM5D!1.44!26.79!KDM5D;;chr10:35484053..35484076,+!p1@CREM!1.42!61.65!CREM;;chr15:60884706..60884743,-!p1@RORA!1.41!122.65!RORA;;chr9:117150254..117150271,-!p1@AKNA!1.39!62.95!AKNA;;chr17:38020392..38020477,-!p1@IKZF3!1.39!23.41!IKZF3;;chr2:192015701..192015743,-!p1@STAT4!1.36!29.91!STAT4;;chr2:231090471..231090504,+!p2@SP140!1.36!21.85!SP140;;chr7:50343895..50343936,+!p5@IKZF1!1.35!21.33!IKZF1;;chr6:391743..391759,+!p1@IRF4!1.33!20.29!IRF4;;chr19:19729477..19729542,-!p1@PBX4!1.32!41.75!PBX4;;chr2:192015750..192015793,-!p2@STAT4!1.31!25.88!STAT4;;chr17:37934280..37934299,-!p6@IKZF3!1.30!18.73!IKZF3;;chr7:50344251..50344288,+!p3@IKZF1!1.29!18.47!IKZF1;;chr19:16435625..16435682,+!p1@KLF2!1.28!564.59!KLF2;;chr12:56415246..56415286,+!p2@IKZF4!1.28!18.08!IKZF4;;chr7:50348268..50348366,+!p4@IKZF1!1.28!18.08!IKZF1;;chr20:56195525..56195556,-!p2@ZBP1!1.28!18.08!ZBP1;;chr19:36204309..36204335,+!p1@ZBTB32!1.27!17.56!ZBTB32;;chr1:92951607..92951661,-!p1@GFI1!1.27!17.43!GFI1;;chr6:106546808..106546833,+!p3@PRDM1!1.26!21.46!PRDM1;;chr16:88752889..88752921,-!p1@SNAI3!1.26!20.16!SNAI3;;chr3:12330560..12330579,+!p1@PPARG!1.25!19.25!PPARG;;chr14:99738138..99738163,-!p1@BCL11B!1.24!16.52!BCL11B;;chr7:50344289..50344323,+!p1@IKZF1!1.24!16.26!IKZF1;;chr19:19779686..19779697,+!p3@ZNF101!1.22!18.21!ZNF101;;chr16:79634581..79634592,-!p4@MAF!1.22!15.74!MAF;;chr16:68119324..68119364,+!p1@NFATC3!1.20!65.03!NFATC3;;chr17:45810594..45810608,+!p1@TBX21!1.18!14.18!TBX21;;chr17:38020557..38020572,-!p4@IKZF3!1.14!12.75!IKZF3;;chr3:63953435..63953499,+!p1@ATXN7!1.13!12.36!ATXN7;;chr3:141105705..141105770,+!p4@ZBTB38!1.12!14.70!ZBTB38;;chr7:137620650..137620677,-!p3@CREB3L2!1.11!11.97!CREB3L2;;chr16:79633894..79633954,-!p3@MAF!1.10!22.37!MAF;;chr13:41593425..41593480,-!p1@ELF1!1.09!72.31!ELF1;;chr3:71355163..71355209,-!p5@FOXP1!1.08!15.22!FOXP1;;chr3:18480217..18480239,-!p3@SATB1!1.08!11.06!SATB1;;chr17:37934188..37934202,-!p8@IKZF3!1.07!10.79!IKZF3;;chr12:56415287..56415300,+!p5@IKZF4!1.07!10.66!IKZF4;;chr7:77428066..77428132,+!p2@PHTF2!1.06!68.15!PHTF2;;chr1:23857698..23857733,-!p1@E2F2!1.06!19.51!E2F2;;chr11:47236584..47236679,+!p1@DDB2!1.04!109.38!DDB2;;chr10:8095593..8095625,+!p3@GATA3!1.04!11.71!GATA3;;chr8:60031619..60031676,-!p1@TOX!1.01!20.16!TOX;;chr2:97202991..97203043,+!p3@ARID5A!1.01!9.23!ARID5A;;chr17:38020516..38020544,-!p5@IKZF3!1.00!8.97!IKZF3;;chr4:185395633..185395651,-!p2@IRF2!0.98!13.79!IRF2;;chr17:1959369..1959388,+!p2@HIC1!0.97!22.76!HIC1;;chr10:104154246..104154347,+!p3@NFKB2!0.96!50.98!NFKB2;;chr14:75988851..75988862,+!p3@BATF!0.96!8.19!BATF;;chr16:88752861..88752884,-!p2@SNAI3!0.96!8.06!SNAI3;;chr5:131826457..131826514,-!p1@IRF1!0.95!322.68!IRF1;;chr4:57522598..57522664,-!p3@HOPX!0.94!7.80!HOPX;;chr9:20621927..20621996,-!p3@MLLT3!0.92!12.49!MLLT3;;chr2:242556880..242556899,-!p5@THAP4!0.92!7.28!THAP4;;chr3:48282587..48282603,+!p1@ZNF589!0.90!32.12!ZNF589;;chr21:36421535..36421610,-!p2@RUNX1!0.90!25.88!RUNX1;;chr6:106546786..106546802,+!p6@PRDM1!0.90!7.02!PRDM1;;chr14:99737850..99737852,-!p3@BCL11B!0.90!7.02!BCL11B;;chr11:128392085..128392232,-!p1@ETS1!0.89!240.09!ETS1;;chr6:106546834..106546850,+!p4@PRDM1!0.89!6.76!PRDM1;;chr6:106547079..106547114,+!p9@PRDM1!0.88!6.63!PRDM1;;chr7:137620684..137620711,-!p4@CREB3L2!0.88!6.63!CREB3L2;;chr17:56565257..56565283,-!p2@HSF5!0.88!6.63!HSF5;;chr1:25291475..25291511,-!p2@RUNX3!0.88!6.50!RUNX3;;chr10:8097321..8097348,+!p4@GATA3!0.88!6.50!GATA3;;chr11:128563948..128564003,+!p1@FLI1!0.87!81.81!FLI1;;chr14:99738059..99738086,-!p2@BCL11B!0.87!6.37!BCL11B;;chr21:36421147..36421193,-!p10@RUNX1!0.87!6.37!RUNX1;;chr7:50343864..50343888,+!p7@IKZF1!0.87!6.37!IKZF1;;chr11:111249993..111250006,-!p1@POU2AF1!0.86!6.24!POU2AF1;;chr1:92949331..92949377,-!p2@GFI1!0.86!6.24!GFI1;;chr9:20622444..20622468,-!p2@MLLT3!0.85!20.94!MLLT3;;chr6:106546731..106546755,+!p5@PRDM1!0.85!6.11!PRDM1;;chr10:35484804..35484902,+!p2@CREM!0.84!24.19!CREM;;chr19:42636586..42636607,-!p1@POU2F2!0.84!17.30!POU2F2;;chr2:214015343..214015366,-!p3@IKZF2!0.84!5.98!IKZF2;;chr11:67007548..67007610,+!p3@KDM2A!0.83!45.65!KDM2A;;chr6:106534192..106534224,+!p1@PRDM1!0.82!16.78!PRDM1;;chr6:45390269..45390298,+!p5@RUNX2!0.82!9.62!RUNX2;;chr4:185395590..185395627,-!p3@IRF2!0.82!7.02!IRF2;;chrY:2803415..2803468,+!p1@ZFY!0.81!5.46!ZFY;;chr1:158978768..158978800,+!p8@IFI16!0.81!5.46!IFI16;;chr10:35484090..35484104,+!p6@CREM!0.81!5.46!CREM;;chr2:238600933..238600985,+!p3@LRRFIP1!0.80!31.21!LRRFIP1;;chr4:81104895..81104920,+!p2@PRDM8!0.79!7.93!PRDM8;;chr2:242556900..242556916,-!p6@THAP4!0.79!5.20!THAP4;;chr13:41240717..41240735,-!p2@FOXO1!0.78!37.72!FOXO1;;chr11:128392273..128392308,-!p2@ETS1!0.78!23.02!ETS1;;chr17:46621146..46621180,-!p10@HOXB2!0.78!5.07!HOXB2;;chr15:31619326..31619390,+!p2@KLF13!0.77!61.65!KLF13;;chr15:74833584..74833626,+!p1@ARID3B!0.77!12.10!ARID3B;;chr11:615570..615721,-!p2@IRF7!0.77!10.14!IRF7;;chr7:128577972..128578047,+!p1@IRF5!0.77!8.06!IRF5;;chr7:50344144..50344157,+!p6@IKZF1!0.77!4.94!IKZF1;;chr16:89787937..89787971,+!p1@ZNF276!0.76!13.40!ZNF276;;chr4:57522166..57522260,-!p2@HOPX!0.76!5.59!HOPX;;chr2:231084659..231084721,-!p1@SP110!0.75!119.00!SP110;;chr7:139762641..139762768,-!p1@PARP12!0.75!70.62!PARP12;;chr6:15249128..15249177,+!p4@JARID2!0.75!8.71!JARID2;;chr4:57522674..57522699,-!p5@HOPX!0.75!4.68!HOPX;;chr2:97202480..97202499,+!p1@ARID5A!0.74!50.46!ARID5A;;chr2:148778973..148779035,+!p3@MBD5!0.74!12.62!MBD5;;chr7:21467802..21467840,+!p3@SP4!0.73!9.75!SP4;;chr14:24630902..24630948,+!p2@IRF9!0.73!5.46!IRF9;;chr16:79634464..79634493,-!p5@MAF!0.73!4.42!MAF;;chr13:41240737..41240787,-!p1@FOXO1!0.72!56.71!FOXO1;;chr10:35416142..35416169,+!p3@CREM!0.72!12.23!CREM;;chr6:45390300..45390335,+!p4@RUNX2!0.72!6.89!RUNX2;;chr10:8100691..8100732,+!p5@GATA3!0.72!4.29!GATA3;;chr17:37934268..37934277,-!p10@IKZF3!0.72!4.29!IKZF3;;chr17:40440481..40440550,+!p1@STAT5A!0.71!33.56!STAT5A;;chr3:71007344..71007348,-!p6@FOXP1!0.71!18.21!FOXP1;;chr12:46123273..46123329,+!p3@ARID2!0.71!7.54!ARID2;;chr10:3824332..3824425,-!p4@KLF6!0.71!7.15!KLF6;;chr1:44679370..44679422,+!p3@DMAP1!0.71!5.72!DMAP1;;chr19:4153613..4153652,+!p1@CREB3L3!0.71!4.16!CREB3L3;;chr2:214013461..214013517,-!p6@IKZF2!0.71!4.16!IKZF2;;chr2:231090344..231090361,-!p3@SP110!0.71!4.16!SP110;;chr1:158979686..158979745,+!p1@IFI16!0.70!150.61!IFI16;;chr14:90085458..90085557,-!p1@FOXN3!0.70!47.73!FOXN3;;chr7:148982396..148982408,+!p4@ZNF783!0.70!4.03!ZNF783;;chr20:46130672..46130686,+!p2@NCOA3!0.69!19.51!NCOA3;;chr11:113930425..113930471,+!p1@ZBTB16!0.69!5.98!ZBTB16;;chr2:74741569..74741620,+!p1@TLX2!0.69!3.90!TLX2;;chr3:18480173..18480189,-!p6@SATB1!0.69!3.90!SATB1;;chr6:45389791..45389832,+!p3@RUNX2!0.68!10.53!RUNX2;;chr3:141121847..141121868,+!p5@ZBTB38!0.68!6.11!ZBTB38;;chr6:36355513..36355578,-!p2@ETV7!0.68!4.94!ETV7;;chr17:38020481..38020506,-!p7@IKZF3!0.68!3.77!IKZF3;;chrY:21906761..21906810,-!p2@KDM5D!0.68!3.77!KDM5D;;chr5:321810..321877,+!p1@AHRR!0.67!13.01!AHRR;;chr6:106534230..106534254,+!p2@PRDM1!0.67!10.14!PRDM1;;chr14:64970670..64970712,-!p3@ZBTB25!0.67!8.71!ZBTB25;;chr1:151319654..151319698,-!p2@RFX5!0.67!8.71!RFX5;;chr9:20622478..20622525,-!p1@MLLT3!0.66!32.38!MLLT3;;chr4:185395191..185395226,-!p4@IRF2!0.66!5.20!IRF2;;chr2:178128250..178128293,-!p6@NFE2L2!0.65!9.88!NFE2L2;;chr17:46621101..46621143,-!p7@HOXB2!0.65!4.94!HOXB2;;chr12:72056800..72056834,+!p1@THAP2!0.65!4.94!THAP2;;chr11:47237922..47237964,+!p4@DDB2!0.65!4.16!DDB2;;chr4:81104865..81104886,+!p6@PRDM8!0.65!3.77!PRDM8;;chr15:60884747..60884774,-!p3@RORA!0.64!9.36!RORA;;chr1:154975110..154975149,+!p2@ZBTB7B!0.64!7.93!ZBTB7B;;chr2:214015111..214015179,-!p1@IKZF2!0.64!6.50!IKZF2;;chr17:36861735..36861755,+!p4@MLLT6!0.64!6.24!MLLT6;;chr17:46621311..46621332,-!p8@HOXB2!0.64!4.55!HOXB2;;chr21:36421347..36421380,-!p8@RUNX1!0.64!3.38!RUNX1;;chr19:52674696..52674758,-!p1@ZNF836!0.63!10.92!ZNF836;;chr20:44600199..44600219,-!p3@ZNF335!0.63!4.68!ZNF335;;chr9:117150303..117150312,-!p3@AKNA!0.63!4.29!AKNA;;chr4:57522513..57522548,-!p4@HOPX!0.63!3.25!HOPX;;chr17:41738709..41738733,-!p3@MEOX1!0.63!3.25!MEOX1;;chr19:16435705..16435726,+!p3@KLF2!0.63!3.25!KLF2;;chr16:68118689..68118733,+!p3@NFATC3!0.62!9.10!NFATC3;;chr19:45972701..45972774,+!p2@FOSB!0.62!4.55!FOSB;;chr17:41738750..41738764,-!p4@MEOX1!0.62!3.12!MEOX1;;chr10:104154415..104154434,+!p5@NFKB2!0.62!3.12!NFKB2;;chr11:128331703..128331717,-!p8@ETS1!0.62!3.12!ETS1;;chr5:176738887..176738934,-!p1@MXD3!0.61!24.58!MXD3;;chr10:104155480..104155534,+!p2@NFKB2!0.61!23.54!NFKB2;;chr6:91006518..91006570,-!p1@BACH2!0.61!7.93!BACH2;;chr3:71179699..71179744,-!p2@FOXP1!0.60!26.66!FOXP1;;chr7:64838786..64838809,+!p2@ZNF92!0.60!20.42!ZNF92;;chr6:20403916..20403965,+!p3@E2F3!0.60!15.74!E2F3;;chr3:18466787..18466839,-!p1@SATB1!0.60!15.74!SATB1;;chr7:21467674..21467727,+!p1@SP4!0.60!14.05!SP4;;chr6:36355431..36355466,-!p1@ETV7!0.60!2.99!ETV7;;chr17:37934392..37934398,-!p11@IKZF3!0.60!2.99!IKZF3;;chr11:615942..615957,-!p1@IRF7!0.59!33.04!IRF7;;chr7:99156145..99156207,+!p5@ZNF655!0.59!11.45!ZNF655;;chr9:3525727..3525828,-!p2@RFX3!0.59!8.58!RFX3;;chr11:128392309..128392350,-!p3@ETS1!0.5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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000084;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000542;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000624;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000789;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000893;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 40: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|top_motifs= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD4%252bCD25%252bCD45RA-%2520memory%2520regulatory%2520T%2520cells%2520expanded%252c%2520donor3.CNhs13812.11920-125H3.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD4%252bCD25%252bCD45RA-%2520memory%2520regulatory%2520T%2520cells%2520expanded%252c%2520donor3.CNhs13812.11920-125H3.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD4%252bCD25%252bCD45RA-%2520memory%2520regulatory%2520T%2520cells%2520expanded%252c%2520donor3.CNhs13812.11920-125H3.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD4%252bCD25%252bCD45RA-%2520memory%2520regulatory%2520T%2520cells%2520expanded%252c%2520donor3.CNhs13812.11920-125H3.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD4%252bCD25%252bCD45RA-%2520memory%2520regulatory%2520T%2520cells%2520expanded%252c%2520donor3.CNhs13812.11920-125H3.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11920-125H3 | |||
|is_a=EFO:0002091;;FF:0000002;;FF:0000210 | |||
|is_obsolete= | |||
|library_id=CNhs13812 | |||
|library_id_phase_based=2:CNhs13812 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11920 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11920 | |||
|name=CD4+CD25+CD45RA- memory regulatory T cells expanded, donor3 | |||
|namespace= | |||
|part_of= | |||
|profile_cagescan= | |||
|profile_hcage=CNhs13812,LSID1092,release014,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq= | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
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| |||
|rna_box=125 | |||
|rna_catalog_number= | |||
|rna_concentration=0.497 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number=67-68 | |||
|rna_od260/230=1.99 | |||
|rna_od260/280=1.63 | |||
|rna_position=H3 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=125H3 | |||
|rna_weight_ug=4.97 | |||
|sample_age=23 | |||
|sample_category=primary cells | |||
|sample_cell_catalog= | |||
|sample_cell_line= | |||
|sample_cell_lot= | |||
|sample_cell_type=T cell | |||
|sample_collaboration=Michael Rehli (University of Regensberg) | |||
|sample_company= | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease= | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;7.99353649157638e-226!GO:0043227;membrane-bound organelle;1.99139523316361e-194!GO:0043231;intracellular membrane-bound organelle;5.3901272908992e-194!GO:0043226;organelle;1.50248725814501e-183!GO:0043229;intracellular organelle;7.70645243252225e-183!GO:0005737;cytoplasm;1.90607061417168e-153!GO:0044422;organelle part;2.07018244470404e-130!GO:0044446;intracellular organelle part;1.24447332103037e-128!GO:0044444;cytoplasmic part;8.32504509468291e-107!GO:0032991;macromolecular complex;4.97414047861377e-103!GO:0044237;cellular metabolic process;4.78361184510961e-96!GO:0043170;macromolecule metabolic process;4.51299909135942e-94!GO:0044238;primary metabolic process;1.56930587184007e-92!GO:0005634;nucleus;1.64728444165974e-92!GO:0030529;ribonucleoprotein complex;7.45541511607628e-85!GO:0044428;nuclear part;4.72382563875279e-76!GO:0003723;RNA binding;9.28354004346985e-75!GO:0043233;organelle lumen;1.59192678563101e-66!GO:0031974;membrane-enclosed lumen;1.59192678563101e-66!GO:0005739;mitochondrion;5.4891655575571e-64!GO:0005515;protein binding;2.0707874657625e-63!GO:0043283;biopolymer metabolic process;5.15898749894501e-60!GO:0006412;translation;2.30790566354852e-55!GO:0019538;protein metabolic process;8.65033030484546e-55!GO:0043234;protein complex;2.22564218790818e-53!GO:0044267;cellular protein metabolic process;6.48680944915331e-51!GO:0044260;cellular macromolecule metabolic process;8.0222374480988e-50!GO:0005840;ribosome;6.83024440013116e-49!GO:0006396;RNA processing;1.22360893842105e-48!GO:0033036;macromolecule localization;5.3653742043165e-47!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.96070068248172e-46!GO:0010467;gene expression;4.13839670179174e-46!GO:0015031;protein transport;1.59940867335588e-45!GO:0044429;mitochondrial part;2.86339945307955e-44!GO:0045184;establishment of protein localization;4.35654244569637e-44!GO:0031981;nuclear lumen;5.72838054729303e-44!GO:0008104;protein localization;7.50052861689216e-44!GO:0003735;structural constituent of ribosome;2.08943149327194e-43!GO:0016071;mRNA metabolic process;2.81873579766251e-43!GO:0009059;macromolecule biosynthetic process;1.46466601767119e-42!GO:0031090;organelle membrane;1.64693754381506e-42!GO:0031967;organelle envelope;1.9298683363865e-42!GO:0031975;envelope;4.50051786201874e-42!GO:0033279;ribosomal subunit;2.07893941341597e-38!GO:0006259;DNA metabolic process;2.39318669530605e-38!GO:0006397;mRNA processing;4.4687818704691e-37!GO:0008380;RNA splicing;6.51380771087564e-37!GO:0044249;cellular biosynthetic process;7.27025365464901e-36!GO:0009058;biosynthetic process;8.72079009322796e-36!GO:0016043;cellular component organization and biogenesis;2.42914918255956e-35!GO:0005829;cytosol;1.82240593560152e-34!GO:0046907;intracellular transport;2.77947197266446e-34!GO:0065003;macromolecular complex assembly;3.01525420235474e-33!GO:0006886;intracellular protein transport;1.13751090604583e-32!GO:0003676;nucleic acid binding;5.07381758615446e-31!GO:0005740;mitochondrial envelope;3.35258876333406e-29!GO:0022607;cellular component assembly;4.53598293561418e-29!GO:0005654;nucleoplasm;7.86683793994262e-29!GO:0000166;nucleotide binding;1.74695444788197e-28!GO:0022613;ribonucleoprotein complex biogenesis and assembly;2.26971548877309e-28!GO:0006996;organelle organization and biogenesis;2.45530271641433e-28!GO:0005830;cytosolic ribosome (sensu Eukaryota);3.02706998317433e-28!GO:0005681;spliceosome;3.77792322824803e-28!GO:0006915;apoptosis;4.37564026507293e-28!GO:0012501;programmed cell death;4.78000985427642e-28!GO:0031966;mitochondrial membrane;6.431986745686e-28!GO:0019866;organelle inner membrane;1.05451057945372e-27!GO:0008219;cell death;8.89672634117979e-27!GO:0016265;death;8.89672634117979e-27!GO:0043228;non-membrane-bound organelle;4.27759012739587e-26!GO:0043232;intracellular non-membrane-bound organelle;4.27759012739587e-26!GO:0007049;cell cycle;1.2203224578548e-25!GO:0051641;cellular localization;3.41338869635063e-25!GO:0051649;establishment of cellular localization;3.81942781681174e-25!GO:0044445;cytosolic part;3.91160697742515e-25!GO:0005743;mitochondrial inner membrane;5.63232832278731e-25!GO:0006512;ubiquitin cycle;6.1375763173499e-23!GO:0044451;nucleoplasm part;4.57204315176514e-22!GO:0006974;response to DNA damage stimulus;4.83998383890567e-22!GO:0032553;ribonucleotide binding;6.06524873667241e-22!GO:0032555;purine ribonucleotide binding;6.06524873667241e-22!GO:0006119;oxidative phosphorylation;7.29850945157446e-22!GO:0005694;chromosome;1.07616100450577e-21!GO:0043412;biopolymer modification;2.29952437908846e-21!GO:0017076;purine nucleotide binding;3.25535108035858e-21!GO:0016070;RNA metabolic process;3.82589214549592e-21!GO:0044427;chromosomal part;3.22882959267395e-20!GO:0022402;cell cycle process;3.40947285488823e-20!GO:0015935;small ribosomal subunit;3.93031005255564e-20!GO:0005524;ATP binding;6.75508711737497e-20!GO:0044455;mitochondrial membrane part;6.80092568443586e-20!GO:0016462;pyrophosphatase activity;8.84543562461249e-20!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;9.13744856237196e-20!GO:0042981;regulation of apoptosis;1.24932560770667e-19!GO:0016817;hydrolase activity, acting on acid anhydrides;1.24932560770667e-19!GO:0022618;protein-RNA complex assembly;1.393263132987e-19!GO:0017111;nucleoside-triphosphatase activity;1.58547550555503e-19!GO:0016874;ligase activity;1.76258511921835e-19!GO:0043067;regulation of programmed cell death;2.01548457248631e-19!GO:0015934;large ribosomal subunit;2.01548457248631e-19!GO:0051276;chromosome organization and biogenesis;2.86411956952925e-19!GO:0032559;adenyl ribonucleotide binding;5.61979770382202e-19!GO:0044265;cellular macromolecule catabolic process;5.76506329798371e-19!GO:0006464;protein modification process;5.97839661153103e-19!GO:0031980;mitochondrial lumen;7.11336639256105e-19!GO:0005759;mitochondrial matrix;7.11336639256105e-19!GO:0006281;DNA repair;3.48891763203788e-18!GO:0030554;adenyl nucleotide binding;4.63677161580224e-18!GO:0043687;post-translational protein modification;1.79873454819342e-17!GO:0006605;protein targeting;1.02167457811974e-16!GO:0005746;mitochondrial respiratory chain;1.29488838639978e-16!GO:0019941;modification-dependent protein catabolic process;2.77795517834795e-16!GO:0043632;modification-dependent macromolecule catabolic process;2.77795517834795e-16!GO:0051603;proteolysis involved in cellular protein catabolic process;2.8764940765541e-16!GO:0006325;establishment and/or maintenance of chromatin architecture;3.14616111658292e-16!GO:0000502;proteasome complex (sensu Eukaryota);4.19975994131974e-16!GO:0008135;translation factor activity, nucleic acid binding;5.56745480664522e-16!GO:0000278;mitotic cell cycle;5.79216903934302e-16!GO:0012505;endomembrane system;5.89831540328709e-16!GO:0006511;ubiquitin-dependent protein catabolic process;6.45913254652703e-16!GO:0044257;cellular protein catabolic process;7.69255078576104e-16!GO:0005730;nucleolus;1.29878059351144e-15!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.43054480640698e-15!GO:0006323;DNA packaging;1.74776369861861e-15!GO:0043285;biopolymer catabolic process;1.83100514273631e-15!GO:0008134;transcription factor binding;1.98374362360028e-15!GO:0050136;NADH dehydrogenase (quinone) activity;2.59916547732077e-15!GO:0003954;NADH dehydrogenase activity;2.59916547732077e-15!GO:0008137;NADH dehydrogenase (ubiquinone) activity;2.59916547732077e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);2.68008773477791e-15!GO:0042623;ATPase activity, coupled;3.35581111950123e-15!GO:0006913;nucleocytoplasmic transport;4.11521982206338e-15!GO:0006457;protein folding;5.06740160429115e-15!GO:0016887;ATPase activity;5.23492953271318e-15!GO:0009057;macromolecule catabolic process;7.40288690819561e-15!GO:0051169;nuclear transport;8.2201485581606e-15!GO:0016604;nuclear body;1.70109541952484e-14!GO:0005635;nuclear envelope;4.92828935568237e-14!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);5.21253274320184e-14!GO:0065004;protein-DNA complex assembly;6.17451574878546e-14!GO:0048770;pigment granule;6.75543265871811e-14!GO:0042470;melanosome;6.75543265871811e-14!GO:0005761;mitochondrial ribosome;8.75624938069931e-14!GO:0000313;organellar ribosome;8.75624938069931e-14!GO:0044248;cellular catabolic process;1.29654335763205e-13!GO:0009719;response to endogenous stimulus;1.79113258804596e-13!GO:0042775;organelle ATP synthesis coupled electron transport;1.85070164005717e-13!GO:0042773;ATP synthesis coupled electron transport;1.85070164005717e-13!GO:0000398;nuclear mRNA splicing, via spliceosome;2.37587924339653e-13!GO:0000375;RNA splicing, via transesterification reactions;2.37587924339653e-13!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;2.37587924339653e-13!GO:0030964;NADH dehydrogenase complex (quinone);2.84713957205472e-13!GO:0045271;respiratory chain complex I;2.84713957205472e-13!GO:0005747;mitochondrial respiratory chain complex I;2.84713957205472e-13!GO:0051726;regulation of cell cycle;3.0180851976277e-13!GO:0006793;phosphorus metabolic process;3.0180851976277e-13!GO:0006796;phosphate metabolic process;3.0180851976277e-13!GO:0000785;chromatin;3.38824745656827e-13!GO:0006333;chromatin assembly or disassembly;3.55145291794848e-13!GO:0022403;cell cycle phase;4.42334467790933e-13!GO:0000074;regulation of progression through cell cycle;5.15023121774353e-13!GO:0000087;M phase of mitotic cell cycle;6.92007714184101e-13!GO:0003743;translation initiation factor activity;7.94044039841379e-13!GO:0031965;nuclear membrane;9.1955354504465e-13!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;9.58688482584954e-13!GO:0006413;translational initiation;1.2402602675524e-12!GO:0007067;mitosis;1.27969582316149e-12!GO:0030163;protein catabolic process;5.9137939836047e-12!GO:0051186;cofactor metabolic process;9.04272892463698e-12!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.3747304124436e-11!GO:0004386;helicase activity;2.27228336266388e-11!GO:0044453;nuclear membrane part;3.90264389144134e-11!GO:0016607;nuclear speck;4.19341040974815e-11!GO:0007249;I-kappaB kinase/NF-kappaB cascade;4.74595179557327e-11!GO:0051082;unfolded protein binding;5.06761328657252e-11!GO:0016310;phosphorylation;5.57727847674415e-11!GO:0050794;regulation of cellular process;5.74691780438867e-11!GO:0017038;protein import;5.83201441831132e-11!GO:0008639;small protein conjugating enzyme activity;6.37973477624707e-11!GO:0006260;DNA replication;7.44724237264786e-11!GO:0006446;regulation of translational initiation;7.5990750725165e-11!GO:0006334;nucleosome assembly;1.09076504449428e-10!GO:0000279;M phase;1.17848083715849e-10!GO:0004842;ubiquitin-protein ligase activity;1.40234880560488e-10!GO:0051301;cell division;1.79250290564747e-10!GO:0019787;small conjugating protein ligase activity;2.04169140336028e-10!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;2.32363569108666e-10!GO:0005794;Golgi apparatus;3.9450250987614e-10!GO:0043069;negative regulation of programmed cell death;4.13627579641711e-10!GO:0006916;anti-apoptosis;4.20625529635173e-10!GO:0031497;chromatin assembly;4.34198388966392e-10!GO:0048193;Golgi vesicle transport;4.48398635291595e-10!GO:0005783;endoplasmic reticulum;4.49954941393256e-10!GO:0042254;ribosome biogenesis and assembly;5.32864583744225e-10!GO:0007243;protein kinase cascade;5.32898768185793e-10!GO:0043066;negative regulation of apoptosis;5.51854719734989e-10!GO:0051246;regulation of protein metabolic process;6.2827297976179e-10!GO:0008026;ATP-dependent helicase activity;7.11709756879895e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;7.79633055114565e-10!GO:0044432;endoplasmic reticulum part;1.20111506966129e-09!GO:0016787;hydrolase activity;1.21387233915477e-09!GO:0016568;chromatin modification;1.64364747647697e-09!GO:0006917;induction of apoptosis;1.64364747647697e-09!GO:0003712;transcription cofactor activity;1.97648183359826e-09!GO:0019829;cation-transporting ATPase activity;2.18894753542595e-09!GO:0043065;positive regulation of apoptosis;2.33313540854931e-09!GO:0012502;induction of programmed cell death;2.35799211747525e-09!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;2.81777895652548e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;2.84064368693428e-09!GO:0005643;nuclear pore;2.97014224255845e-09!GO:0043068;positive regulation of programmed cell death;3.07983953515547e-09!GO:0006732;coenzyme metabolic process;4.19435985476072e-09!GO:0043566;structure-specific DNA binding;4.36938138438795e-09!GO:0008565;protein transporter activity;6.60904233099343e-09!GO:0009259;ribonucleotide metabolic process;8.53826789855906e-09!GO:0048523;negative regulation of cellular process;1.029188466314e-08!GO:0005839;proteasome core complex (sensu Eukaryota);1.06272794482555e-08!GO:0005768;endosome;1.12340812648194e-08!GO:0016881;acid-amino acid ligase activity;1.16444843512576e-08!GO:0016192;vesicle-mediated transport;1.23132752493365e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.2536237572265e-08!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.50528197500074e-08!GO:0050657;nucleic acid transport;1.54748650727079e-08!GO:0051236;establishment of RNA localization;1.54748650727079e-08!GO:0050658;RNA transport;1.54748650727079e-08!GO:0006403;RNA localization;1.84425720269309e-08!GO:0051170;nuclear import;2.15460827341921e-08!GO:0015078;hydrogen ion transmembrane transporter activity;2.23508654096572e-08!GO:0065002;intracellular protein transport across a membrane;2.40863042948328e-08!GO:0006399;tRNA metabolic process;2.48878749121291e-08!GO:0003697;single-stranded DNA binding;2.64012129431907e-08!GO:0006164;purine nucleotide biosynthetic process;2.7591211844363e-08!GO:0006163;purine nucleotide metabolic process;2.85009440051757e-08!GO:0009260;ribonucleotide biosynthetic process;3.01662528955247e-08!GO:0009055;electron carrier activity;3.18885460393139e-08!GO:0042175;nuclear envelope-endoplasmic reticulum network;3.88383170635393e-08!GO:0006606;protein import into nucleus;4.1805504685975e-08!GO:0005789;endoplasmic reticulum membrane;4.30501640858846e-08!GO:0065009;regulation of a molecular function;4.56584960218803e-08!GO:0016740;transferase activity;4.58338659446041e-08!GO:0016772;transferase activity, transferring phosphorus-containing groups;4.93391904449674e-08!GO:0009152;purine ribonucleotide biosynthetic process;5.58862833810737e-08!GO:0009150;purine ribonucleotide metabolic process;6.10992833368337e-08!GO:0046930;pore complex;6.2378574552105e-08!GO:0030532;small nuclear ribonucleoprotein complex;6.73701803673125e-08!GO:0048519;negative regulation of biological process;6.81278912591562e-08!GO:0004298;threonine endopeptidase activity;7.11399895366341e-08!GO:0015986;ATP synthesis coupled proton transport;7.11399895366341e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;7.11399895366341e-08!GO:0051188;cofactor biosynthetic process;1.17405321176156e-07!GO:0016779;nucleotidyltransferase activity;1.59277849896788e-07!GO:0048522;positive regulation of cellular process;1.88149385667546e-07!GO:0006366;transcription from RNA polymerase II promoter;2.02020945020331e-07!GO:0000786;nucleosome;2.12378093371727e-07!GO:0019899;enzyme binding;2.85086193329565e-07!GO:0051028;mRNA transport;4.75678976063657e-07!GO:0048475;coated membrane;5.03387053028692e-07!GO:0030117;membrane coat;5.03387053028692e-07!GO:0009060;aerobic respiration;5.73182881077825e-07!GO:0008632;apoptotic program;5.85307912877052e-07!GO:0006754;ATP biosynthetic process;6.29691669494757e-07!GO:0006753;nucleoside phosphate metabolic process;6.29691669494757e-07!GO:0007005;mitochondrion organization and biogenesis;6.33198211278089e-07!GO:0032446;protein modification by small protein conjugation;6.65270451027053e-07!GO:0005773;vacuole;6.65270451027053e-07!GO:0009142;nucleoside triphosphate biosynthetic process;6.74836134443548e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;6.74836134443548e-07!GO:0050789;regulation of biological process;7.04265985152338e-07!GO:0016469;proton-transporting two-sector ATPase complex;7.50267743841494e-07!GO:0030120;vesicle coat;7.66086598946579e-07!GO:0030662;coated vesicle membrane;7.66086598946579e-07!GO:0009056;catabolic process;8.06840793313399e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;9.79363632755126e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;9.79363632755126e-07!GO:0006461;protein complex assembly;1.0515425489391e-06!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.15404549764876e-06!GO:0004812;aminoacyl-tRNA ligase activity;1.15404549764876e-06!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.15404549764876e-06!GO:0016567;protein ubiquitination;1.36802066475431e-06!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;1.43542645175132e-06!GO:0015399;primary active transmembrane transporter activity;1.43542645175132e-06!GO:0009199;ribonucleoside triphosphate metabolic process;1.46121455560475e-06!GO:0016072;rRNA metabolic process;1.54568488708656e-06!GO:0000323;lytic vacuole;1.55330135631104e-06!GO:0005764;lysosome;1.55330135631104e-06!GO:0009141;nucleoside triphosphate metabolic process;1.55925996009911e-06!GO:0006364;rRNA processing;1.67607449837539e-06!GO:0000245;spliceosome assembly;1.72807850277956e-06!GO:0019222;regulation of metabolic process;1.99489911076606e-06!GO:0043038;amino acid activation;2.05425364707837e-06!GO:0006418;tRNA aminoacylation for protein translation;2.05425364707837e-06!GO:0043039;tRNA aminoacylation;2.05425364707837e-06!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.06920088362669e-06!GO:0009144;purine nucleoside triphosphate metabolic process;2.06920088362669e-06!GO:0045786;negative regulation of progression through cell cycle;2.09567676936312e-06!GO:0006888;ER to Golgi vesicle-mediated transport;2.1094795487789e-06!GO:0046034;ATP metabolic process;2.23717372565087e-06!GO:0007242;intracellular signaling cascade;2.31425877580563e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;2.60785266226032e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;2.65237151635793e-06!GO:0003713;transcription coactivator activity;2.72516039093529e-06!GO:0045259;proton-transporting ATP synthase complex;2.80488997945636e-06!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;3.08086518103975e-06!GO:0004674;protein serine/threonine kinase activity;3.20597326673101e-06!GO:0031324;negative regulation of cellular metabolic process;3.84192730783875e-06!GO:0005793;ER-Golgi intermediate compartment;4.55543086360142e-06!GO:0045333;cellular respiration;5.21241657618415e-06!GO:0016563;transcription activator activity;5.88671493413977e-06!GO:0016564;transcription repressor activity;6.27493747154787e-06!GO:0006261;DNA-dependent DNA replication;6.83586148396922e-06!GO:0009108;coenzyme biosynthetic process;7.43880601670037e-06!GO:0005813;centrosome;7.74100247116067e-06!GO:0006613;cotranslational protein targeting to membrane;1.06567252603096e-05!GO:0005815;microtubule organizing center;1.12771045565867e-05!GO:0006310;DNA recombination;1.21066935235428e-05!GO:0003724;RNA helicase activity;1.21657361681786e-05!GO:0006417;regulation of translation;1.3361778611257e-05!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.34515713398003e-05!GO:0000151;ubiquitin ligase complex;1.45542070907339e-05!GO:0005762;mitochondrial large ribosomal subunit;1.48950811002798e-05!GO:0000315;organellar large ribosomal subunit;1.48950811002798e-05!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.70161014564534e-05!GO:0051168;nuclear export;1.85941829293717e-05!GO:0006099;tricarboxylic acid cycle;2.10615981314997e-05!GO:0046356;acetyl-CoA catabolic process;2.10615981314997e-05!GO:0006401;RNA catabolic process;2.11856945002254e-05!GO:0000775;chromosome, pericentric region;2.59341269873359e-05!GO:0006752;group transfer coenzyme metabolic process;2.65449855838642e-05!GO:0043492;ATPase activity, coupled to movement of substances;2.7728908604144e-05!GO:0042110;T cell activation;3.03972003722229e-05!GO:0009892;negative regulation of metabolic process;3.24675917880874e-05!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;3.28709021865343e-05!GO:0048518;positive regulation of biological process;3.33867509520862e-05!GO:0005819;spindle;3.4116155169543e-05!GO:0015630;microtubule cytoskeleton;3.55817865846903e-05!GO:0006084;acetyl-CoA metabolic process;4.53076982860154e-05!GO:0005770;late endosome;4.70386867976064e-05!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;4.70761868695281e-05!GO:0048468;cell development;6.21117315362098e-05!GO:0006612;protein targeting to membrane;6.51307489224128e-05!GO:0006402;mRNA catabolic process;7.29659844477501e-05!GO:0031323;regulation of cellular metabolic process;7.5502811921739e-05!GO:0003690;double-stranded DNA binding;7.61991931563789e-05!GO:0005798;Golgi-associated vesicle;8.35331098042143e-05!GO:0000075;cell cycle checkpoint;8.53872287338357e-05!GO:0050790;regulation of catalytic activity;8.57240995536643e-05!GO:0005525;GTP binding;8.57240995536643e-05!GO:0009615;response to virus;8.57661468077399e-05!GO:0044440;endosomal part;9.59533790705677e-05!GO:0010008;endosome membrane;9.59533790705677e-05!GO:0043623;cellular protein complex assembly;0.000109840219013968!GO:0044431;Golgi apparatus part;0.000115640754354864!GO:0009117;nucleotide metabolic process;0.000121599207257281!GO:0005657;replication fork;0.00012179192566241!GO:0009967;positive regulation of signal transduction;0.00012542047028026!GO:0015992;proton transport;0.000125846321847942!GO:0051325;interphase;0.000132526099356085!GO:0030384;phosphoinositide metabolic process;0.000132526099356085!GO:0006818;hydrogen transport;0.000143712761558909!GO:0031326;regulation of cellular biosynthetic process;0.000144269439742471!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000146920364087489!GO:0008654;phospholipid biosynthetic process;0.000148119256081905!GO:0005885;Arp2/3 protein complex;0.000158797046082952!GO:0051187;cofactor catabolic process;0.000163739751276708!GO:0009109;coenzyme catabolic process;0.00016680334415769!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000170669538441065!GO:0065007;biological regulation;0.000184659091554052!GO:0051329;interphase of mitotic cell cycle;0.000193223043082859!GO:0003899;DNA-directed RNA polymerase activity;0.000215814632917368!GO:0008186;RNA-dependent ATPase activity;0.000221211599067295!GO:0007088;regulation of mitosis;0.000239482782266761!GO:0005667;transcription factor complex;0.000282520785156774!GO:0006650;glycerophospholipid metabolic process;0.000299271603539472!GO:0051427;hormone receptor binding;0.000300128666720627!GO:0016363;nuclear matrix;0.00030155975595874!GO:0003924;GTPase activity;0.000318298927393513!GO:0006352;transcription initiation;0.000342248317497569!GO:0000314;organellar small ribosomal subunit;0.000353899631774986!GO:0005763;mitochondrial small ribosomal subunit;0.000353899631774986!GO:0008234;cysteine-type peptidase activity;0.00037935088191711!GO:0003729;mRNA binding;0.000409147122526055!GO:0008094;DNA-dependent ATPase activity;0.000418508740863613!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000419298684975516!GO:0008637;apoptotic mitochondrial changes;0.000429036684620906!GO:0043021;ribonucleoprotein binding;0.000460375954736331!GO:0045454;cell redox homeostasis;0.000482533932547099!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000549617731374699!GO:0035257;nuclear hormone receptor binding;0.000598842180981707!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000601114920170877!GO:0005741;mitochondrial outer membrane;0.000607639130846619!GO:0060090;molecular adaptor activity;0.000616301653512495!GO:0004004;ATP-dependent RNA helicase activity;0.00066118237678536!GO:0016481;negative regulation of transcription;0.00066118237678536!GO:0003684;damaged DNA binding;0.000663574547719012!GO:0005637;nuclear inner membrane;0.000666348422424362!GO:0046489;phosphoinositide biosynthetic process;0.000669639635724091!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00067393308643315!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000691626622992621!GO:0042802;identical protein binding;0.000693671661572898!GO:0030658;transport vesicle membrane;0.000723621074606361!GO:0030118;clathrin coat;0.000747660690310344!GO:0000287;magnesium ion binding;0.000749447658557489!GO:0032561;guanyl ribonucleotide binding;0.000795435984722857!GO:0019001;guanyl nucleotide binding;0.000795435984722857!GO:0019867;outer membrane;0.000837699800318564!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.000860077554672878!GO:0006891;intra-Golgi vesicle-mediated transport;0.000898316583484383!GO:0051251;positive regulation of lymphocyte activation;0.000946188979152926!GO:0007006;mitochondrial membrane organization and biogenesis;0.000967692609300043!GO:0006302;double-strand break repair;0.000973407430747729!GO:0051252;regulation of RNA metabolic process;0.000981000422285117!GO:0006414;translational elongation;0.000987692409056591!GO:0006350;transcription;0.000988665478699069!GO:0003678;DNA helicase activity;0.00107661731265793!GO:0031968;organelle outer membrane;0.00109483036160026!GO:0009889;regulation of biosynthetic process;0.00114337075432553!GO:0019843;rRNA binding;0.00115875018051359!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00118557239649909!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00118557239649909!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00118557239649909!GO:0008624;induction of apoptosis by extracellular signals;0.00125226480831037!GO:0046649;lymphocyte activation;0.00125809485618119!GO:0043681;protein import into mitochondrion;0.00127497338011132!GO:0006611;protein export from nucleus;0.00130305690722825!GO:0016853;isomerase activity;0.00134177274943854!GO:0005769;early endosome;0.00144352415377138!GO:0030660;Golgi-associated vesicle membrane;0.00155398279271468!GO:0051090;regulation of transcription factor activity;0.0016707583985409!GO:0046474;glycerophospholipid biosynthetic process;0.00171564096566667!GO:0003714;transcription corepressor activity;0.00172691033031909!GO:0051249;regulation of lymphocyte activation;0.00173072881588151!GO:0051092;activation of NF-kappaB transcription factor;0.00181658524554426!GO:0050865;regulation of cell activation;0.00181658524554426!GO:0006289;nucleotide-excision repair;0.00182556292807379!GO:0006383;transcription from RNA polymerase III promoter;0.00191485298111651!GO:0015631;tubulin binding;0.00192760787004896!GO:0019955;cytokine binding;0.00192760787004896!GO:0031982;vesicle;0.00196637479949243!GO:0019210;kinase inhibitor activity;0.00197698970797081!GO:0000139;Golgi membrane;0.00200291425026115!GO:0004518;nuclease activity;0.00206181916440451!GO:0001836;release of cytochrome c from mitochondria;0.00208081053249082!GO:0048500;signal recognition particle;0.00212142670563266!GO:0005774;vacuolar membrane;0.00213457034455272!GO:0016301;kinase activity;0.00220937796766389!GO:0022890;inorganic cation transmembrane transporter activity;0.00225259931904767!GO:0004860;protein kinase inhibitor activity;0.00240168726923772!GO:0051052;regulation of DNA metabolic process;0.00243265339550155!GO:0010468;regulation of gene expression;0.00252959860274879!GO:0032259;methylation;0.00257183984628765!GO:0016311;dephosphorylation;0.00271133697034316!GO:0051223;regulation of protein transport;0.00280640751486933!GO:0001772;immunological synapse;0.00282891833976443!GO:0043414;biopolymer methylation;0.00282891833976443!GO:0000776;kinetochore;0.00286506072875496!GO:0016251;general RNA polymerase II transcription factor activity;0.00289609476801779!GO:0016791;phosphoric monoester hydrolase activity;0.00293134092957391!GO:0050863;regulation of T cell activation;0.00303472272178261!GO:0031072;heat shock protein binding;0.00306412117958103!GO:0004177;aminopeptidase activity;0.00338708114125662!GO:0007051;spindle organization and biogenesis;0.00343519678871639!GO:0046822;regulation of nucleocytoplasmic transport;0.00356300365896296!GO:0051920;peroxiredoxin activity;0.0035811376772101!GO:0048471;perinuclear region of cytoplasm;0.00368561889337395!GO:0008033;tRNA processing;0.00372733063640375!GO:0005765;lysosomal membrane;0.00372988670346487!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00388081438094365!GO:0005684;U2-dependent spliceosome;0.00399015036286877!GO:0007259;JAK-STAT cascade;0.00399015036286877!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0040350340660953!GO:0045047;protein targeting to ER;0.0040350340660953!GO:0051087;chaperone binding;0.00408711802720257!GO:0007093;mitotic cell cycle checkpoint;0.0040989139332615!GO:0043488;regulation of mRNA stability;0.00413403098214381!GO:0043487;regulation of RNA stability;0.00413403098214381!GO:0008312;7S RNA binding;0.00422585189091589!GO:0019901;protein kinase binding;0.00425933499167943!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.00426041658608387!GO:0050870;positive regulation of T cell activation;0.00438384994730396!GO:0051789;response to protein stimulus;0.00439857218349848!GO:0006986;response to unfolded protein;0.00439857218349848!GO:0006839;mitochondrial transport;0.00457902123418931!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00464277624304634!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00464277624304634!GO:0005070;SH3/SH2 adaptor activity;0.00475305708238326!GO:0007264;small GTPase mediated signal transduction;0.00490872807077398!GO:0000082;G1/S transition of mitotic cell cycle;0.00500357830863481!GO:0006338;chromatin remodeling;0.00506657075063079!GO:0016197;endosome transport;0.00507457607215893!GO:0044437;vacuolar part;0.00515572066042916!GO:0004527;exonuclease activity;0.00515572066042916!GO:0008022;protein C-terminus binding;0.00530276362923239!GO:0016741;transferase activity, transferring one-carbon groups;0.00531737947209564!GO:0045321;leukocyte activation;0.00534991210883721!GO:0005048;signal sequence binding;0.0053517676382101!GO:0022415;viral reproductive process;0.00535681711567646!GO:0031902;late endosome membrane;0.00538105070313387!GO:0009165;nucleotide biosynthetic process;0.00539047330352296!GO:0047485;protein N-terminus binding;0.00539047330352296!GO:0019900;kinase binding;0.00539047330352296!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.00539890899507929!GO:0008168;methyltransferase activity;0.00558310317005058!GO:0031410;cytoplasmic vesicle;0.00562122153425771!GO:0046966;thyroid hormone receptor binding;0.00582773541961236!GO:0031988;membrane-bound vesicle;0.00587910184973912!GO:0007050;cell cycle arrest;0.00590690342262854!GO:0008270;zinc ion binding;0.00594639215561849!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.00606541552887125!GO:0043281;regulation of caspase activity;0.00622121230952743!GO:0006607;NLS-bearing substrate import into nucleus;0.00625467920023213!GO:0030518;steroid hormone receptor signaling pathway;0.00634389453482667!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00635270993279092!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00640693904814958!GO:0031252;leading edge;0.00642912591890689!GO:0018193;peptidyl-amino acid modification;0.00648134942264931!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00648134942264931!GO:0051059;NF-kappaB binding;0.00662674320583786!GO:0051336;regulation of hydrolase activity;0.00672943992659411!GO:0016788;hydrolase activity, acting on ester bonds;0.00680083792759877!GO:0003682;chromatin binding;0.00693142427861078!GO:0016584;nucleosome positioning;0.00709052320026075!GO:0007059;chromosome segregation;0.00736133452045163!GO:0030125;clathrin vesicle coat;0.00757954747164438!GO:0030665;clathrin coated vesicle membrane;0.00757954747164438!GO:0000209;protein polyubiquitination;0.00764754507133479!GO:0046467;membrane lipid biosynthetic process;0.00779145428921691!GO:0003746;translation elongation factor activity;0.00788445717358058!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00796318626903965!GO:0015002;heme-copper terminal oxidase activity;0.00796318626903965!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00796318626903965!GO:0004129;cytochrome-c oxidase activity;0.00796318626903965!GO:0008139;nuclear localization sequence binding;0.00822296928331425!GO:0003711;transcription elongation regulator activity;0.00822430741793835!GO:0016605;PML body;0.00842336997300896!GO:0048487;beta-tubulin binding;0.0085338207654398!GO:0030119;AP-type membrane coat adaptor complex;0.00853736568925851!GO:0051098;regulation of binding;0.00853736568925851!GO:0008047;enzyme activator activity;0.00853736568925851!GO:0045936;negative regulation of phosphate metabolic process;0.008751613305148!GO:0006626;protein targeting to mitochondrion;0.00890501811224504!GO:0030880;RNA polymerase complex;0.00901121083535014!GO:0000049;tRNA binding;0.00939377635640874!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0094294929249442!GO:0031124;mRNA 3'-end processing;0.00961397397389651!GO:0032508;DNA duplex unwinding;0.00974264609750332!GO:0032392;DNA geometric change;0.00974264609750332!GO:0006505;GPI anchor metabolic process;0.0100587967675513!GO:0030176;integral to endoplasmic reticulum membrane;0.0104680798422629!GO:0006506;GPI anchor biosynthetic process;0.0106833930948039!GO:0006405;RNA export from nucleus;0.0107414400135535!GO:0004721;phosphoprotein phosphatase activity;0.0107943414295288!GO:0030131;clathrin adaptor complex;0.0108041247545853!GO:0022411;cellular component disassembly;0.010903810843451!GO:0006595;polyamine metabolic process;0.0111383665673976!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0112186240579576!GO:0006497;protein amino acid lipidation;0.011243154420263!GO:0006284;base-excision repair;0.0115688644634139!GO:0051881;regulation of mitochondrial membrane potential;0.0117811885689613!GO:0006007;glucose catabolic process;0.0117811885689613!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0118184718551993!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.011940336077949!GO:0007265;Ras protein signal transduction;0.0121012373586714!GO:0032200;telomere organization and biogenesis;0.0121986859323193!GO:0000723;telomere maintenance;0.0121986859323193!GO:0032940;secretion by cell;0.0122724657547763!GO:0046983;protein dimerization activity;0.0124181756999976!GO:0043621;protein self-association;0.0125916253678677!GO:0006091;generation of precursor metabolites and energy;0.0128438895131448!GO:0045892;negative regulation of transcription, DNA-dependent;0.0129662794981202!GO:0016272;prefoldin complex;0.0131633411354717!GO:0030663;COPI coated vesicle membrane;0.0132014037889605!GO:0030126;COPI vesicle coat;0.0132014037889605!GO:0016023;cytoplasmic membrane-bound vesicle;0.013349349558032!GO:0019904;protein domain specific binding;0.0138985547672395!GO:0042393;histone binding;0.0140711624708338!GO:0045076;regulation of interleukin-2 biosynthetic process;0.0141195840251724!GO:0030137;COPI-coated vesicle;0.0146837601278859!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0147265555120955!GO:0051539;4 iron, 4 sulfur cluster binding;0.0150468746042532!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.0150849049973091!GO:0033116;ER-Golgi intermediate compartment membrane;0.0150849049973091!GO:0006013;mannose metabolic process;0.0151570825159288!GO:0051235;maintenance of localization;0.015462036148096!GO:0030132;clathrin coat of coated pit;0.0156434681240987!GO:0030521;androgen receptor signaling pathway;0.0158007531143946!GO:0030522;intracellular receptor-mediated signaling pathway;0.016064001920509!GO:0040029;regulation of gene expression, epigenetic;0.0161091477118108!GO:0016859;cis-trans isomerase activity;0.0163592744094989!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.0164486447669414!GO:0000428;DNA-directed RNA polymerase complex;0.0164486447669414!GO:0019318;hexose metabolic process;0.0165081144347722!GO:0005996;monosaccharide metabolic process;0.0165448959166098!GO:0006268;DNA unwinding during replication;0.016675401121341!GO:0051540;metal cluster binding;0.016675401121341!GO:0051536;iron-sulfur cluster binding;0.016675401121341!GO:0002440;production of molecular mediator of immune response;0.016675401121341!GO:0030867;rough endoplasmic reticulum membrane;0.016675401121341!GO:0030127;COPII vesicle coat;0.0167579149746944!GO:0012507;ER to Golgi transport vesicle membrane;0.0167579149746944!GO:0050811;GABA receptor binding;0.0167643586297729!GO:0006468;protein amino acid phosphorylation;0.0167997553351425!GO:0004003;ATP-dependent DNA helicase activity;0.0170036469974086!GO:0015923;mannosidase activity;0.0174595973279461!GO:0042770;DNA damage response, signal transduction;0.0175155461156977!GO:0044452;nucleolar part;0.0179347944850549!GO:0046426;negative regulation of JAK-STAT cascade;0.0182067167513057!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0183306757497035!GO:0010257;NADH dehydrogenase complex assembly;0.0183306757497035!GO:0033108;mitochondrial respiratory chain complex assembly;0.0183306757497035!GO:0043596;nuclear replication fork;0.0184810005752696!GO:0043433;negative regulation of transcription factor activity;0.0186102026429158!GO:0006950;response to stress;0.0186939906426974!GO:0006672;ceramide metabolic process;0.0186939906426974!GO:0016569;covalent chromatin modification;0.0187587889313854!GO:0030134;ER to Golgi transport vesicle;0.0187587889313854!GO:0042101;T cell receptor complex;0.0188842275663639!GO:0008629;induction of apoptosis by intracellular signals;0.0190800812829028!GO:0004722;protein serine/threonine phosphatase activity;0.0192350027873597!GO:0042532;negative regulation of tyrosine phosphorylation of STAT protein;0.0192895646649706!GO:0042518;negative regulation of tyrosine phosphorylation of Stat3 protein;0.0192895646649706!GO:0050732;negative regulation of peptidyl-tyrosine phosphorylation;0.0192895646649706!GO:0042326;negative regulation of phosphorylation;0.0193073714927753!GO:0003677;DNA binding;0.0195245350172033!GO:0006778;porphyrin metabolic process;0.0196697923611706!GO:0033013;tetrapyrrole metabolic process;0.0196697923611706!GO:0000228;nuclear chromosome;0.0196697923611706!GO:0046519;sphingoid metabolic process;0.0196902836293186!GO:0003725;double-stranded RNA binding;0.0201895931293993!GO:0045086;positive regulation of interleukin-2 biosynthetic process;0.0203902886912327!GO:0048002;antigen processing and presentation of peptide antigen;0.0206861649602614!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0207790816905782!GO:0005869;dynactin complex;0.0210363312926871!GO:0046979;TAP2 binding;0.0210689603295195!GO:0046977;TAP binding;0.0210689603295195!GO:0046978;TAP1 binding;0.0210689603295195!GO:0008017;microtubule binding;0.0210712590094038!GO:0000059;protein import into nucleus, docking;0.0211384407853594!GO:0005788;endoplasmic reticulum lumen;0.0212980288636433!GO:0019783;small conjugating protein-specific protease activity;0.0213060466132787!GO:0045045;secretory pathway;0.0213418321134165!GO:0030133;transport vesicle;0.0214873173882454!GO:0006458;'de novo' protein folding;0.021491310831921!GO:0051084;'de novo' posttranslational protein folding;0.021491310831921!GO:0006376;mRNA splice site selection;0.0215866454347671!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0215866454347671!GO:0005095;GTPase inhibitor activity;0.0217169830925952!GO:0004428;inositol or phosphatidylinositol kinase activity;0.021772460683274!GO:0031625;ubiquitin protein ligase binding;0.0219753948347215!GO:0007040;lysosome organization and biogenesis;0.0219810224807435!GO:0006470;protein amino acid dephosphorylation;0.0220313013280199!GO:0004576;oligosaccharyl transferase activity;0.022487985787402!GO:0032774;RNA biosynthetic process;0.0226844866545242!GO:0004532;exoribonuclease activity;0.0227048704197558!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0227048704197558!GO:0008213;protein amino acid alkylation;0.0230067956112165!GO:0006479;protein amino acid methylation;0.0230067956112165!GO:0046483;heterocycle metabolic process;0.0231457281774084!GO:0006779;porphyrin biosynthetic process;0.0236973167763837!GO:0033014;tetrapyrrole biosynthetic process;0.0236973167763837!GO:0031123;RNA 3'-end processing;0.0236973167763837!GO:0030258;lipid modification;0.0240675473463814!GO:0000339;RNA cap binding;0.0244557579196456!GO:0005031;tumor necrosis factor receptor activity;0.0245867435174676!GO:0005669;transcription factor TFIID complex;0.0248260622111966!GO:0016763;transferase activity, transferring pentosyl groups;0.0248351852217274!GO:0004843;ubiquitin-specific protease activity;0.0248422415648421!GO:0019976;interleukin-2 binding;0.0250082678376226!GO:0004911;interleukin-2 receptor activity;0.0250082678376226!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.025024609966211!GO:0006919;caspase activation;0.0252677070381538!GO:0004197;cysteine-type endopeptidase activity;0.0253390788372475!GO:0006351;transcription, DNA-dependent;0.0254063787349221!GO:0043022;ribosome binding;0.0254630455456168!GO:0044438;microbody part;0.0256265599131439!GO:0044439;peroxisomal part;0.0256265599131439!GO:0000738;DNA catabolic process, exonucleolytic;0.0258595245689168!GO:0008287;protein serine/threonine phosphatase complex;0.025962954438999!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0262760122372855!GO:0051338;regulation of transferase activity;0.0272028155560413!GO:0007034;vacuolar transport;0.0272290815429611!GO:0042094;interleukin-2 biosynthetic process;0.0272457650534216!GO:0000288;mRNA catabolic process, deadenylation-dependent decay;0.0272457650534216!GO:0000792;heterochromatin;0.0272638606865252!GO:0008408;3'-5' exonuclease activity;0.0272687463977405!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0275180939544097!GO:0042289;MHC class II protein binding;0.0277315099320707!GO:0016570;histone modification;0.0287422714902173!GO:0030217;T cell differentiation;0.0290394888682819!GO:0033673;negative regulation of kinase activity;0.0290733858191822!GO:0006469;negative regulation of protein kinase activity;0.0290733858191822!GO:0007052;mitotic spindle organization and biogenesis;0.0293891943284363!GO:0000781;chromosome, telomeric region;0.029430713502906!GO:0051219;phosphoprotein binding;0.0295966850994826!GO:0008250;oligosaccharyl transferase complex;0.0298510326511391!GO:0046588;negative regulation of calcium-dependent cell-cell adhesion;0.0298510326511391!GO:0046586;regulation of calcium-dependent cell-cell adhesion;0.0298510326511391!GO:0042158;lipoprotein biosynthetic process;0.0307390525849366!GO:0006914;autophagy;0.0310269522736459!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.0310538792607632!GO:0001784;phosphotyrosine binding;0.0310740909930644!GO:0009124;nucleoside monophosphate biosynthetic process;0.0310740909930644!GO:0009123;nucleoside monophosphate metabolic process;0.0310740909930644!GO:0030833;regulation of actin filament polymerization;0.0311775825892012!GO:0004907;interleukin receptor activity;0.0312155591970054!GO:0003988;acetyl-CoA C-acyltransferase activity;0.0312155591970054!GO:0009112;nucleobase metabolic process;0.0315972567372426!GO:0008320;protein transmembrane transporter activity;0.0323089137380339!GO:0045309;protein phosphorylated amino acid binding;0.0323374160717313!GO:0008276;protein methyltransferase activity;0.0329658015595734!GO:0044262;cellular carbohydrate metabolic process;0.0330111802744924!GO:0045603;positive regulation of endothelial cell differentiation;0.0331875333279609!GO:0030695;GTPase regulator activity;0.0332251224627505!GO:0042608;T cell receptor binding;0.0333021974679142!GO:0048524;positive regulation of viral reproduction;0.0337776471670914!GO:0035258;steroid hormone receptor binding;0.0337776471670914!GO:0016790;thiolester hydrolase activity;0.0341952032719885!GO:0005832;chaperonin-containing T-complex;0.0348727983408574!GO:0019220;regulation of phosphate metabolic process;0.0349202973066929!GO:0051174;regulation of phosphorus metabolic process;0.0349202973066929!GO:0042168;heme metabolic process;0.034957416900595!GO:0008538;proteasome activator activity;0.0352036624462969!GO:0005791;rough endoplasmic reticulum;0.0352492190924686!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0353663827665156!GO:0006378;mRNA polyadenylation;0.0354747517433828!GO:0046982;protein heterodimerization activity;0.0355129322761526!GO:0030433;ER-associated protein catabolic process;0.0355129322761526!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0355129322761526!GO:0051348;negative regulation of transferase activity;0.0357795380181918!GO:0031903;microbody membrane;0.0357795380181918!GO:0005778;peroxisomal membrane;0.0357795380181918!GO:0031647;regulation of protein stability;0.0357795380181918!GO:0051452;cellular pH reduction;0.0357795380181918!GO:0051453;regulation of cellular pH;0.0357795380181918!GO:0045851;pH reduction;0.0357795380181918!GO:0046365;monosaccharide catabolic process;0.0360572434845497!GO:0043284;biopolymer biosynthetic process;0.0362783097432917!GO:0006643;membrane lipid metabolic process;0.0362783097432917!GO:0016860;intramolecular oxidoreductase activity;0.0365923620255098!GO:0019079;viral genome replication;0.0365978034029779!GO:0045449;regulation of transcription;0.0368151249091446!GO:0043549;regulation of kinase activity;0.0372573946438581!GO:0030140;trans-Golgi network transport vesicle;0.0373361218779978!GO:0004221;ubiquitin thiolesterase activity;0.0373800628752728!GO:0005521;lamin binding;0.0377871668021825!GO:0006144;purine base metabolic process;0.0380726739695575!GO:0022406;membrane docking;0.0381308058451757!GO:0048278;vesicle docking;0.0381308058451757!GO:0006487;protein amino acid N-linked glycosylation;0.0385105398997708!GO:0005784;translocon complex;0.0385767940519898!GO:0005092;GDP-dissociation inhibitor activity;0.0387114277721943!GO:0009966;regulation of signal transduction;0.038852375278864!GO:0044454;nuclear chromosome part;0.039007352476391!GO:0002483;antigen processing and presentation of endogenous peptide antigen;0.0393277687041249!GO:0019885;antigen processing and presentation of endogenous peptide antigen via MHC class I;0.0393277687041249!GO:0000152;nuclear ubiquitin ligase complex;0.0396114096058389!GO:0003950;NAD+ ADP-ribosyltransferase activity;0.0396605840130283!GO:0022884;macromolecule transmembrane transporter activity;0.0396605840130283!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0396605840130283!GO:0017134;fibroblast growth factor binding;0.0397545311035588!GO:0007033;vacuole organization and biogenesis;0.0403759839605269!GO:0006904;vesicle docking during exocytosis;0.0403763989581383!GO:0006275;regulation of DNA replication;0.0410089994984038!GO:0016491;oxidoreductase activity;0.0410089994984038!GO:0002820;negative regulation of adaptive immune response;0.0410089994984038!GO:0002823;negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0410089994984038!GO:0015980;energy derivation by oxidation of organic compounds;0.0410290462987672!GO:0051091;positive regulation of transcription factor activity;0.0410730529663545!GO:0006783;heme biosynthetic process;0.0413352119121559!GO:0050852;T cell receptor signaling pathway;0.0415497983342649!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0418457202466469!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0427224873543434!GO:0043280;positive regulation of caspase activity;0.0434039280315019!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0439754819076196!GO:0008180;signalosome;0.0440772892380982!GO:0005035;death receptor activity;0.0442623305546731!GO:0046914;transition metal ion binding;0.0446679714713272!GO:0005876;spindle microtubule;0.044808080011372!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0453506198180696!GO:0030130;clathrin coat of trans-Golgi network vesicle;0.0453506198180696!GO:0012510;trans-Golgi network transport vesicle membrane;0.0453506198180696!GO:0000118;histone deacetylase complex;0.0454507827593885!GO:0002521;leukocyte differentiation;0.0454878133057199!GO:0006730;one-carbon compound metabolic process;0.0460031232118387!GO:0045185;maintenance of protein localization;0.0464379104522279!GO:0006518;peptide metabolic process;0.0470753508875032!GO:0046164;alcohol catabolic process;0.0473290492070371!GO:0051287;NAD binding;0.0476312368432841!GO:0045069;regulation of viral genome replication;0.0483588711807418!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0484787556522651!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0487110574989651!GO:0051051;negative regulation of transport;0.049128329735904!GO:0045941;positive regulation of transcription;0.0491778927752697 | |||
|sample_id=11920 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=ZBTB16:2.648765926;CDX1,2,4:2.43853293192;ELF1,2,4:2.19550301786;PAX3,7:1.94248506727;NKX6-1,2:1.87360274927;RUNX1..3:1.8668992977;RORA:1.77381426686;FOXP1:1.76486935923;TLX2:1.76001749268;PITX1..3:1.71641916125;PAX4:1.60877059883;IKZF2:1.4236032448;ETS1,2:1.38723592196;IRF1,2:1.38216549507;FOX{F1,F2,J1}:1.27493328159;POU2F1..3:1.23609723979;BPTF:1.20747822078;AIRE:1.19315739663;NKX3-1:1.16480235588;SPI1:1.15838181867;PDX1:1.12860971994;DMAP1_NCOR{1,2}_SMARC:0.984220096909;GATA6:0.897978620632;POU1F1:0.880024491481;TOPORS:0.87676103384;HMX1:0.779149168996;STAT2,4,6:0.775366749153;ELK1,4_GABP{A,B1}:0.770697482229;CRX:0.769424678164;FOX{D1,D2}:0.742713378514;CREB1:0.738516342072;FOXO1,3,4:0.694629936223;ZNF384:0.654811273283;SPIB:0.651477830993;E2F1..5:0.644102492201;BREu{core}:0.624644998771;STAT1,3:0.616290180613;PBX1:0.581931166652;NFKB1_REL_RELA:0.580992581495;ATF5_CREB3:0.559113142704;IRF7:0.556841952171;NANOG{mouse}:0.524080269105;ZEB1:0.467995490084;STAT5{A,B}:0.457479792058;YY1:0.452218438625;LMO2:0.428363878389;RFX2..5_RFXANK_RFXAP:0.397440228241;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.39237032999;TGIF1:0.371833678702;MYOD1:0.357123156099;SNAI1..3:0.346963422676;FOX{I1,J2}:0.344220334715;NFY{A,B,C}:0.307470196858;FOXQ1:0.279566130344;PAX2:0.272014946276;NKX2-2,8:0.261474625523;PAX8:0.244844402539;OCT4_SOX2{dimer}:0.235636775495;HES1:0.23523370363;SOX5:0.215827026302;HOX{A6,A7,B6,B7}:0.209401763301;SPZ1:0.19042046223;FOXN1:0.187154419596;MYB:0.15732880082;SMAD1..7,9:0.150275524975;ATF4:0.143284982152;EVI1:0.136188738616;SREBF1,2:0.118141773417;JUN:0.106373877949;DBP:0.104879166463;FOXD3:0.0916832600276;FOXM1:0.0889919139023;NR5A1,2:0.033123400876;NRF1:0.0324878142278;GFI1:0.0128787982164;ONECUT1,2:0.000815693506059;FOXP3:-0.0362972611425;LEF1_TCF7_TCF7L1,2:-0.0939124768552;CUX2:-0.129082403439;TAL1_TCF{3,4,12}:-0.131903266739;EP300:-0.167365949159;HNF4A_NR2F1,2:-0.173000420228;NFATC1..3:-0.175695411424;TP53:-0.202318676941;ZNF143:-0.230540159146;ZNF148:-0.23216906041;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.266789525666;FOXA2:-0.267089305478;NFE2L1:-0.26867257018;NFIL3:-0.319093059145;T:-0.337453740744;ATF2:-0.339743879967;GLI1..3:-0.343207040714;POU3F1..4:-0.3503907225;HAND1,2:-0.358166838359;RXRA_VDR{dimer}:-0.363573732366;NFE2:-0.370908909409;AR:-0.385883251585;SRF:-0.400649480194;HIF1A:-0.411395800364;PRRX1,2:-0.437369354923;TFDP1:-0.445382747361;AHR_ARNT_ARNT2:-0.452289085225;ALX1:-0.461633004511;MYFfamily:-0.46818895818;CEBPA,B_DDIT3:-0.471515942193;FOS_FOS{B,L1}_JUN{B,D}:-0.472868076373;CDC5L:-0.479363717113;SOX2:-0.48562774746;ZNF423:-0.490162679999;RREB1:-0.491792713738;NR6A1:-0.498320575438;BACH2:-0.499546418841;NKX2-1,4:-0.511951337643;NFIX:-0.52491923328;HNF1A:-0.541212523253;NR3C1:-0.544782893153;ATF6:-0.549581043881;NHLH1,2:-0.555908257834;GCM1,2:-0.559040898596;UFEwm:-0.572674812495;HOXA9_MEIS1:-0.609984685907;TFCP2:-0.639862037714;ARID5B:-0.64219850746;ALX4:-0.65942103458;RFX1:-0.674178052266;PAX6:-0.678832809635;NFE2L2:-0.67960140261;MAFB:-0.683076574229;MYBL2:-0.684598058444;SOX{8,9,10}:-0.701066268743;PPARG:-0.720270377108;NR1H4:-0.733819201797;HMGA1,2:-0.737274672236;TFAP4:-0.738126273018;FOSL2:-0.743233957798;TEF:-0.75238550141;REST:-0.779502831006;VSX1,2:-0.803327701243;NKX2-3_NKX2-5:-0.829945320589;XCPE1{core}:-0.851471219631;MED-1{core}:-0.864817260454;HLF:-0.890582171057;ESR1:-0.90883974077;POU5F1:-0.957636048004;ZNF238:-1.00825196921;PRDM1:-1.01086881679;GATA4:-1.02108215373;GFI1B:-1.02511432545;EGR1..3:-1.03390774319;ADNP_IRX_SIX_ZHX:-1.05336282573;ZFP161:-1.08084068978;PAX5:-1.08110126425;MEF2{A,B,C,D}:-1.11988918007;HSF1,2:-1.12237864685;HBP1_HMGB_SSRP1_UBTF:-1.12269037959;ZBTB6:-1.12309707355;bHLH_family:-1.12828150076;MAZ:-1.15504332125;NANOG:-1.17178345675;FOXL1:-1.20788651478;KLF4:-1.22398533547;ESRRA:-1.24521673477;HOX{A5,B5}:-1.25862925061;MTE{core}:-1.27335929668;TFAP2B:-1.2757274588;LHX3,4:-1.29267175389;POU6F1:-1.30935427604;TBP:-1.32497790738;EBF1:-1.32749303074;MTF1:-1.33165117635;MZF1:-1.35090717206;HIC1:-1.3634149322;TFAP2{A,C}:-1.47021493966;GTF2I:-1.47045701904;TBX4,5:-1.47544429602;PATZ1:-1.53082832665;GZF1:-1.53329738673;GTF2A1,2:-1.5358806787;ZIC1..3:-1.54844358784;SP1:-1.58070796266;RBPJ:-1.58654893974;SOX17:-1.63246011052;TEAD1:-1.70193893587;PAX1,9:-1.71094063727;HOX{A4,D4}:-1.72587347229;EN1,2:-1.7489594098;TLX1..3_NFIC{dimer}:-1.80279802964;NKX3-2:-1.82462217381;RXR{A,B,G}:-1.87169601266;IKZF1:-2.09815495534;XBP1:-2.56516085388 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11920-125H3;search_select_hide=table117:FF:11920-125H3 | |||
}} | }} |
Latest revision as of 18:29, 4 June 2020
Name: | CD4+CD25+CD45RA- memory regulatory T cells expanded, donor3 |
---|---|
Species: | Human (Homo sapiens) |
Library ID: | CNhs13812 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13812
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13812
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0883 |
10 | 10 | 0.00689 |
100 | 100 | 0.441 |
101 | 101 | 0.0573 |
102 | 102 | 0.434 |
103 | 103 | 0.49 |
104 | 104 | 0.707 |
105 | 105 | 0.334 |
106 | 106 | 0.332 |
107 | 107 | 0.664 |
108 | 108 | 0.72 |
109 | 109 | 0.0452 |
11 | 11 | 0.0284 |
110 | 110 | 0.353 |
111 | 111 | 0.133 |
112 | 112 | 0.181 |
113 | 113 | 0.312 |
114 | 114 | 0.23 |
115 | 115 | 0.584 |
116 | 116 | 0.449 |
117 | 117 | 0.00208 |
118 | 118 | 0.401 |
119 | 119 | 0.44 |
12 | 12 | 0.585 |
120 | 120 | 0.43 |
121 | 121 | 0.389 |
122 | 122 | 0.699 |
123 | 123 | 2.24352e-7 |
124 | 124 | 0.234 |
125 | 125 | 0.908 |
126 | 126 | 0.459 |
127 | 127 | 0.734 |
128 | 128 | 0.597 |
129 | 129 | 0.63 |
13 | 13 | 0.322 |
130 | 130 | 0.509 |
131 | 131 | 0.759 |
132 | 132 | 0.881 |
133 | 133 | 0.175 |
134 | 134 | 0.729 |
135 | 135 | 0.71 |
136 | 136 | 0.662 |
137 | 137 | 0.0437 |
138 | 138 | 0.21 |
139 | 139 | 0.153 |
14 | 14 | 0.276 |
140 | 140 | 0.127 |
141 | 141 | 0.367 |
142 | 142 | 0.811 |
143 | 143 | 0.0118 |
144 | 144 | 0.391 |
145 | 145 | 0.172 |
146 | 146 | 0.706 |
147 | 147 | 0.0974 |
148 | 148 | 0.0421 |
149 | 149 | 0.909 |
15 | 15 | 0.204 |
150 | 150 | 0.458 |
151 | 151 | 0.556 |
152 | 152 | 0.606 |
153 | 153 | 0.939 |
154 | 154 | 0.418 |
155 | 155 | 0.0446 |
156 | 156 | 0.508 |
157 | 157 | 0.113 |
158 | 158 | 0.226 |
159 | 159 | 0.671 |
16 | 16 | 0.609 |
160 | 160 | 0.429 |
161 | 161 | 0.165 |
162 | 162 | 0.381 |
163 | 163 | 0.54 |
164 | 164 | 0.0848 |
165 | 165 | 0.233 |
166 | 166 | 0.857 |
167 | 167 | 0.239 |
168 | 168 | 0.989 |
169 | 169 | 0.12 |
17 | 17 | 0.715 |
18 | 18 | 0.718 |
19 | 19 | 0.689 |
2 | 2 | 0.796 |
20 | 20 | 0.48 |
21 | 21 | 0.222 |
22 | 22 | 0.821 |
23 | 23 | 0.941 |
24 | 24 | 0.973 |
25 | 25 | 0.149 |
26 | 26 | 0.0357 |
27 | 27 | 0.368 |
28 | 28 | 0.519 |
29 | 29 | 0.0186 |
3 | 3 | 0.0289 |
30 | 30 | 0.0678 |
31 | 31 | 0.908 |
32 | 32 | 0.507 |
33 | 33 | 0.546 |
34 | 34 | 0.926 |
35 | 35 | 0.322 |
36 | 36 | 0.0163 |
37 | 37 | 0.156 |
38 | 38 | 0.598 |
39 | 39 | 0.622 |
4 | 4 | 0.844 |
40 | 40 | 0.199 |
41 | 41 | 0.675 |
42 | 42 | 0.0796 |
43 | 43 | 0.317 |
44 | 44 | 0.363 |
45 | 45 | 0.434 |
46 | 46 | 0.125 |
47 | 47 | 0.0123 |
48 | 48 | 0.0616 |
49 | 49 | 0.0937 |
5 | 5 | 0.828 |
50 | 50 | 0.774 |
51 | 51 | 0.644 |
52 | 52 | 0.51 |
53 | 53 | 0.143 |
54 | 54 | 0.751 |
55 | 55 | 0.756 |
56 | 56 | 0.461 |
57 | 57 | 0.21 |
58 | 58 | 0.119 |
59 | 59 | 0.489 |
6 | 6 | 0.338 |
60 | 60 | 0.379 |
61 | 61 | 0.135 |
62 | 62 | 0.0631 |
63 | 63 | 0.439 |
64 | 64 | 0.161 |
65 | 65 | 0.694 |
66 | 66 | 0.611 |
67 | 67 | 0.97 |
68 | 68 | 0.864 |
69 | 69 | 0.906 |
7 | 7 | 0.3 |
70 | 70 | 0.0455 |
71 | 71 | 0.024 |
72 | 72 | 0.057 |
73 | 73 | 0.39 |
74 | 74 | 0.489 |
75 | 75 | 0.0238 |
76 | 76 | 0.188 |
77 | 77 | 0.747 |
78 | 78 | 0.0527 |
79 | 79 | 0.793 |
8 | 8 | 0.501 |
80 | 80 | 0.295 |
81 | 81 | 0.321 |
82 | 82 | 0.0529 |
83 | 83 | 0.695 |
84 | 84 | 0.0457 |
85 | 85 | 0.984 |
86 | 86 | 0.122 |
87 | 87 | 0.54 |
88 | 88 | 0.844 |
89 | 89 | 0.376 |
9 | 9 | 0.96 |
90 | 90 | 0.0202 |
91 | 91 | 0.477 |
92 | 92 | 0.303 |
93 | 93 | 0.501 |
94 | 94 | 0.133 |
95 | 95 | 0.018 |
96 | 96 | 0.0798 |
97 | 97 | 0.224 |
98 | 98 | 0.119 |
99 | 99 | 0.059 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13812
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000002 in vivo cell sample
FF:0000210 human sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
NA