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{{f5samples
{{f5samples
|F5samples=
|DRA_sample_Accession=CAGE@SAMD00005858
|accession_numbers=CAGE;DRX007796;DRR008668;DRZ000093;DRZ001478;DRZ011443;DRZ012828
|ancestors_in_anatomy_facet=
|ancestors_in_anatomy_facet=
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000004,CL:0000012,CL:0000063,CL:0000066,CL:0000076,CL:0000255,CL:0000548
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0000066,CL:0000076,CL:0000255
|ancestors_in_disease_facet=DOID:0050687,DOID:14566,DOID:162,DOID:1749,DOID:305,DOID:4
|ancestors_in_disease_facet=DOID:4,DOID:162,DOID:14566,DOID:0050687,DOID:305,DOID:1749
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100297,FF:0102024,FF:0101120
|comment=
|comment=
|created_by=
|created_by=
|creation_date=
|creation_date=
|data_phase=2
|datafreeze_phase=2
|def=
|def=
|expression_enrichment_score=chr11:34642612..34642646,+!p1@EHF!2.69!491.06!EHF;;chr17:7493405..7493419,-!p1@SOX15!2.43!267.58!SOX15;;chr6:1312325..1312340,+!p1@FOXQ1!2.42!421.22!FOXQ1;;chr1:201979703..201979721,+!p2@ELF3!2.15!140.16!ELF3;;chr1:209979467..209979494,-!p1@IRF6!2.01!113.70!IRF6;;chr1:201979743..201979762,+!p1@ELF3!1.99!97.77!ELF3;;chr11:34642656..34642667,+!p2@EHF!1.92!81.35!EHF;;chr6:10415484..10415508,-!p3@TFAP2A!1.90!78.17!TFAP2A;;chr10:48355030..48355090,+!p1@ZNF488!1.81!81.35!ZNF488;;chr3:189507432..189507459,+!p1@TP63!1.80!61.51!TP63;;chr8:10588010..10588030,-!p1@SOX7!1.70!49.01!SOX7;;chr11:65554528..65554546,+!p1@OVOL1!1.68!46.56!OVOL1;;chr1:6479968..6479986,-!p1@HES2!1.68!46.56!HES2;;chr8:102504651..102504683,+!p1@GRHL2!1.62!41.17!GRHL2;;chr1:209979411..209979433,-!p2@IRF6!1.54!33.57!IRF6;;chr12:54785074..54785122,-!p2@ZNF385A!1.52!49.25!ZNF385A;;chr10:8096772..8096787,+!p2@GATA3!1.52!37.98!GATA3;;chr19:45971246..45971265,+!p1@FOSB!1.51!552.57!FOSB;;chr11:31832658..31832681,-!p1@PAX6!1.51!31.12!PAX6;;chr5:2751762..2751784,-!p1@IRX2!1.51!31.12!IRX2;;chr17:7492684..7492778,-!p2@SOX15!1.44!55.13!SOX15;;chr1:935398..935465,-!p2@HES4!1.43!52.68!HES4;;chr14:38064429..38064486,-!p1@FOXA1!1.41!24.75!FOXA1;;chr3:111314186..111314204,-!p1@ZBED2!1.39!23.28!ZBED2;;chr13:73633131..73633149,+!p1@KLF5!1.38!238.91!KLF5;;chr8:102504979..102505010,+!p2@GRHL2!1.35!21.32!GRHL2;;chr3:193853927..193853944,+!p1@HES1!1.33!644.21!HES1;;chr2:176969228..176969260,+!p1@HOXD11!1.33!20.58!HOXD11;;chr11:65554563..65554576,+!p2@OVOL1!1.33!20.58!OVOL1;;chr6:10412600..10412637,-!p1@TFAP2A!1.32!32.59!TFAP2A;;chr10:8095593..8095625,+!p3@GATA3!1.30!22.30!GATA3;;chr3:12330560..12330579,+!p1@PPARG!1.30!21.56!PPARG;;chr13:36788658..36788703,-!p2@CCDC169-SOHLH2,p2@SOHLH2!1.30!19.11!SOHLH2;;chr6:10415276..10415341,-!p2@TFAP2A!1.29!22.30!TFAP2A;;chr7:35293685..35293718,-!p1@TBX20!1.25!16.91!TBX20;;chr5:134369905..134369972,-!p1@PITX1!1.24!25.24!PITX1;;chr6:10419768..10419819,-!p6@TFAP2A!1.24!16.42!TFAP2A;;chr11:31832610..31832639,-!p5@PAX6!1.24!16.42!PAX6;;chr11:120107344..120107351,+!p1@POU2F3!1.21!18.62!POU2F3;;chr19:23869970..23869991,-!p1@ZNF675!1.19!54.89!ZNF675;;chr15:83953397..83953425,-!p1@BNC1!1.19!16.66!BNC1;;chr12:19556998..19557013,+!p6@AEBP2!1.19!14.46!AEBP2;;chr12:54785054..54785072,-!p4@ZNF385A!1.17!15.44!ZNF385A;;chr2:176969179..176969226,+!p2@HOXD11!1.15!12.99!HOXD11;;chr20:55204351..55204377,+!p1@TFAP2C!1.14!16.17!TFAP2C;;chr2:45236540..45236577,-!p1@SIX2!1.14!12.74!SIX2;;chr6:1389789..1389821,+!p1@FOXF2!1.13!17.15!FOXF2;;chr20:30193083..30193098,+!p1@ID1!1.12!971.58!ID1;;chr19:58694421..58694485,+!p1@ZNF274!1.12!64.20!ZNF274;;chr22:19748231..19748317,+!p1@TBX1!1.11!12.01!TBX1;;chr7:27192185..27192209,-!p1@HOXA3!1.11!11.76!HOXA3;;chr5:137804484..137804498,+!p2@EGR1!1.10!46.56!EGR1;;chr10:8096631..8096660,+!p1@GATA3!1.09!13.72!GATA3;;chr11:19262421..19262455,-!p3@E2F8!1.09!11.27!E2F8;;chr6:10413188..10413249,-!p7@TFAP2A!1.09!11.27!TFAP2A;;chr20:50721803..50721857,-!p2@ZFP64!1.08!17.40!ZFP64;;chr11:65667846..65667868,-!p1@FOSL1!1.07!286.21!FOSL1;;chr17:46682321..46682362,-!p1@HOXB6!1.07!10.78!HOXB6;;chr12:27485762..27485776,+!p3@ARNTL2!1.06!28.18!ARNTL2;;chr20:31350184..31350200,+!p1@DNMT3B!1.06!22.05!DNMT3B;;chr6:29648890..29648944,-!p1@ZFP57!1.06!10.54!ZFP57;;chr7:27224842..27224872,-!p1@HOXA11!1.06!10.54!HOXA11;;chr2:214015343..214015366,-!p3@IKZF2!1.05!10.29!IKZF2;;chr15:96869511..96869525,+!p16@NR2F2!1.04!11.03!NR2F2;;chr8:102504690..102504704,+!p3@GRHL2!1.04!10.05!GRHL2;;chr11:65667884..65667895,-!p2@FOSL1!1.03!37.98!FOSL1;;chr12:19556960..19556982,+!p10@AEBP2!1.02!9.56!AEBP2;;chr13:28543285..28543314,-!p2@CDX2!1.02!9.56!CDX2;;chrX:2418949..2419024,-!p1@DHRSX,p1@ZBED1!1.02!9.56!ZBED1;;chr11:19263160..19263176,-!p1@E2F8!0.99!10.29!E2F8;;chr19:23433144..23433204,-!p1@ZNF724P!0.98!39.70!ZNF724P;;chr20:42543441..42543497,+!p1@TOX2!0.98!39.45!TOX2;;chr17:46687959..46688007,-!p2@HOXB7!0.97!11.76!HOXB7;;chr2:223163706..223163730,-!p1@PAX3!0.96!8.09!PAX3;;chr19:24097675..24097699,+!p1@ZNF726!0.95!27.20!ZNF726;;chr5:50679228..50679288,+!p1@ISL1!0.95!7.84!ISL1;;chr12:27485785..27485816,+!p1@ARNTL2!0.94!55.38!ARNTL2;;chr2:61108808..61108821,+!p3@REL!0.93!9.56!REL;;chr12:54348655..54348693,+!p1@HOXC12!0.93!7.60!HOXC12;;chr12:26277956..26277980,-!p1@BHLHE41!0.92!27.20!BHLHE41;;chr6:28048343..28048354,+!p1@ZNF165!0.92!7.35!ZNF165;;chr7:27196267..27196311,-!p1@HOXA7!0.91!7.11!HOXA7;;chr6:126240380..126240430,+!p2@NCOA7!0.90!18.87!NCOA7;;chr7:27135591..27135658,-!p1@HOXA1!0.90!13.72!HOXA1;;chr6:10419824..10419840,-!p9@TFAP2A!0.90!6.86!TFAP2A;;chr6:1312155..1312187,+!p2@FOXQ1!0.90!6.86!FOXQ1;;chr14:29235961..29236008,+!p1@FOXG1!0.90!6.86!FOXG1;;chr2:60780753..60780800,-!p1@BCL11A!0.89!34.55!BCL11A;;chr8:106330656..106330684,+!p1@ZFPM2!0.89!18.62!ZFPM2;;chr19:45908292..45908374,-!p1@PPP1R13L!0.88!61.26!PPP1R13L;;chr19:47523058..47523114,+!p1@NPAS1!0.88!6.62!NPAS1;;chr1:3569072..3569093,+!p1@TP73!0.88!6.62!TP73;;chr19:2867325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|fonse_cell_line=FF:0101120
|fonse_cell_line=FF:0101120
|fonse_cell_line_closure=FF:0101120
|fonse_cell_line_closure=FF:0101120
Line 35: Line 40:
|fonse_treatment_closure=
|fonse_treatment_closure=
|has_quality=
|has_quality=
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acantholytic%2520squamous%2520carcinoma%2520cell%2520line%253aHCC1806.CNhs11844.10717-109I6.hg19.nobarcode.bam
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acantholytic%2520squamous%2520carcinoma%2520cell%2520line%253aHCC1806.CNhs11844.10717-109I6.hg19.ctss.bed.gz
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acantholytic%2520squamous%2520carcinoma%2520cell%2520line%253aHCC1806.CNhs11844.10717-109I6.hg19.nobarcode.rdna.fa.gz
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acantholytic%2520squamous%2520carcinoma%2520cell%2520line%253aHCC1806.CNhs11844.10717-109I6.hg38.nobarcode.bam
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acantholytic%2520squamous%2520carcinoma%2520cell%2520line%253aHCC1806.CNhs11844.10717-109I6.hg38.nobarcode.ctss.bed.gz
|id=FF:10717-109I6
|id=FF:10717-109I6
|is_a=EFO:0002091;;FF:0000003;;FF:0000210;;FF:0102024
|is_a=EFO:0002091;;FF:0000210;;FF:0102024
|is_obsolete=
|library_id=CNhs11844
|library_id_phase_based=2:CNhs11844
|microRNAs=
|microRNAs_nn=
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10717
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10717
|name=acantholytic squamous carcinoma cell line:HCC1806
|name=acantholytic squamous carcinoma cell line:HCC1806
|namespace=FANTOM5
|namespace=FANTOM5
Line 42: Line 59:
|profile_cagescan=,,,
|profile_cagescan=,,,
|profile_hcage=CNhs11844,LSID829,release010,COMPLETED
|profile_hcage=CNhs11844,LSID829,release010,COMPLETED
|profile_rnaseq=,,,
|profile_rnaseq=
|profile_srnaseq=,,,
|profile_srnaseq=,,,
|refex=http://refex.dbcls.jp/genelist.php?lang
|repeat_enrich_byfamily=0,0,0.0866048557546315,0.0593253378002861,0,0,0,0.136382442739174,0.0951833797824107,-0.104152420684251,0.0884175886519886,0,0,0,0,0,0,0,0,0,0,0.296700472825561,0.0951833797824107,0,0.0198867011608357,0,0.0866048557546315,0,0,0,0.0752518152412058,0,0,0.300858272769424,0,0,0,0,0,0,0,0,0,0,0.173209711509263,0,-0.0983080270748077,0,0,0,0,0,0,0,0,0.0623898346417972,0,0,0,0,0,0,0.0951833797824107,0.0762173502666582,0,0,-0.00216024743068628,0,0,0,0,0,0,0,0,0.23932967792473,0,0,0,0,0.0951833797824107,0,0,0,0,0.0475916898912054,0,0.0951833797824107,0.0206735025058158,0,0,-0.116492590398256,0.0475916898912054,0,0.0374529227287467,-0.0635465610360426,0.0327639760424855,0,0,0,0,-0.00285197145529574,0.0677924939161015,0,0,0,0,0,0,0,0,0,0,0.206269694716997,0,0,0,0,0,0,0.248992802580662,0.173209711509263,0,0,-0.0703677116666648,-0.328865672909519,0,0,0.0951833797824107,0,0,0.0951833797824107
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|rna_box=109
|rna_box=109
|rna_catalog_number=
|rna_catalog_number=
Line 57: Line 77:
|rna_weight_ug=35.40051
|rna_weight_ug=35.40051
|sample_age=60
|sample_age=60
|sample_category=cell lines
|sample_cell_catalog=CRL-2335
|sample_cell_catalog=CRL-2335
|sample_cell_line=HCC1806
|sample_cell_line=HCC1806
Line 69: Line 90:
|sample_ethnicity=B
|sample_ethnicity=B
|sample_experimental_condition=
|sample_experimental_condition=
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;4.05182233019726e-278!GO:0043226;organelle;3.51141778416546e-222!GO:0043229;intracellular organelle;1.49156120449833e-221!GO:0043231;intracellular membrane-bound organelle;8.35008123821268e-215!GO:0043227;membrane-bound organelle;1.43044739941044e-214!GO:0005737;cytoplasm;1.42894111397631e-182!GO:0044422;organelle part;1.23288613043901e-152!GO:0044446;intracellular organelle part;2.42822678255833e-151!GO:0044444;cytoplasmic part;6.94243982673747e-117!GO:0005634;nucleus;2.01576470545861e-108!GO:0032991;macromolecular complex;1.20509841345551e-106!GO:0044237;cellular metabolic process;6.25082446848106e-102!GO:0044238;primary metabolic process;2.16592430929014e-100!GO:0043170;macromolecule metabolic process;2.25183853762885e-96!GO:0030529;ribonucleoprotein complex;1.3669739777879e-86!GO:0044428;nuclear part;9.73132158917295e-78!GO:0005515;protein binding;1.75831421678745e-74!GO:0043233;organelle lumen;3.86191749184508e-74!GO:0031974;membrane-enclosed lumen;3.86191749184508e-74!GO:0003723;RNA binding;7.78875076892218e-70!GO:0005739;mitochondrion;3.14419191815091e-66!GO:0043283;biopolymer metabolic process;3.922717787659e-60!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.88984939577295e-55!GO:0043234;protein complex;4.30465369972272e-55!GO:0010467;gene expression;1.09013453252549e-53!GO:0005840;ribosome;5.80077779772768e-53!GO:0016043;cellular component organization and biogenesis;6.96365562329139e-53!GO:0006412;translation;3.41954397009709e-52!GO:0006396;RNA processing;5.11928499069628e-49!GO:0019538;protein metabolic process;2.30481435202381e-47!GO:0043228;non-membrane-bound organelle;7.42525580174088e-47!GO:0043232;intracellular non-membrane-bound organelle;7.42525580174088e-47!GO:0003735;structural constituent of ribosome;1.17844120767065e-45!GO:0031981;nuclear lumen;1.43433329511585e-44!GO:0044429;mitochondrial part;1.6231865073837e-44!GO:0005829;cytosol;8.19475670112502e-43!GO:0031967;organelle envelope;1.06338739482703e-41!GO:0031090;organelle membrane;1.19624644611044e-41!GO:0044267;cellular protein metabolic process;1.48944453077543e-41!GO:0006996;organelle organization and biogenesis;1.48944453077543e-41!GO:0044260;cellular macromolecule metabolic process;2.33324869584615e-41!GO:0031975;envelope;2.5628608676911e-41!GO:0006259;DNA metabolic process;1.09399473453547e-40!GO:0044249;cellular biosynthetic process;4.41601847456358e-40!GO:0016071;mRNA metabolic process;2.11752627015131e-39!GO:0009058;biosynthetic process;5.08912460505833e-39!GO:0033036;macromolecule localization;6.89148421481015e-39!GO:0033279;ribosomal subunit;1.70376592052104e-38!GO:0007049;cell cycle;2.09392008977851e-38!GO:0015031;protein transport;2.69896459891409e-38!GO:0065003;macromolecular complex assembly;6.16079957799573e-38!GO:0009059;macromolecule biosynthetic process;2.53837507346962e-37!GO:0008104;protein localization;2.73904738488822e-35!GO:0008380;RNA splicing;4.49279421719155e-35!GO:0045184;establishment of protein localization;4.76719907559261e-35!GO:0003676;nucleic acid binding;4.17423907362561e-34!GO:0006397;mRNA processing;7.97360355176931e-34!GO:0046907;intracellular transport;1.03607781082851e-33!GO:0022607;cellular component assembly;3.48170321942901e-33!GO:0022613;ribonucleoprotein complex biogenesis and assembly;5.57591102958232e-31!GO:0022402;cell cycle process;2.12023868678948e-29!GO:0000278;mitotic cell cycle;1.03318525901109e-28!GO:0005830;cytosolic ribosome (sensu Eukaryota);3.4238439890021e-28!GO:0005654;nucleoplasm;5.9758029784053e-28!GO:0016070;RNA metabolic process;1.13104645414684e-27!GO:0006886;intracellular protein transport;2.60732975870113e-27!GO:0005740;mitochondrial envelope;3.59657499529673e-27!GO:0005681;spliceosome;9.61593462792587e-27!GO:0019866;organelle inner membrane;9.97773917117701e-27!GO:0031966;mitochondrial membrane;1.42803309369316e-25!GO:0000166;nucleotide binding;4.06157167404646e-25!GO:0005694;chromosome;7.5384448899666e-25!GO:0044445;cytosolic part;3.06756192370696e-24!GO:0005743;mitochondrial inner membrane;3.27665168104266e-24!GO:0006974;response to DNA damage stimulus;8.98507933079447e-24!GO:0000087;M phase of mitotic cell cycle;3.53677542868167e-23!GO:0044427;chromosomal part;4.3629582594807e-23!GO:0044451;nucleoplasm part;6.10083912273481e-23!GO:0022403;cell cycle phase;6.8441330901234e-23!GO:0007067;mitosis;7.6476886635213e-23!GO:0051649;establishment of cellular localization;1.41937649729375e-22!GO:0051641;cellular localization;2.73541838425294e-22!GO:0016462;pyrophosphatase activity;1.14132315919724e-21!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.38217437259461e-21!GO:0016817;hydrolase activity, acting on acid anhydrides;1.97012291319138e-21!GO:0031980;mitochondrial lumen;2.32568464113417e-21!GO:0005759;mitochondrial matrix;2.32568464113417e-21!GO:0044455;mitochondrial membrane part;5.14208016404968e-21!GO:0017111;nucleoside-triphosphatase activity;6.225046633527e-21!GO:0006281;DNA repair;1.1195102754868e-20!GO:0006119;oxidative phosphorylation;3.5396302319539e-20!GO:0016874;ligase activity;3.99283400694107e-20!GO:0015934;large ribosomal subunit;4.33657644739723e-20!GO:0000279;M phase;4.33657644739723e-20!GO:0051301;cell division;6.04105318847127e-20!GO:0015935;small ribosomal subunit;1.64291402274847e-19!GO:0051276;chromosome organization and biogenesis;1.98039820108498e-19!GO:0006260;DNA replication;6.25864824442045e-19!GO:0022618;protein-RNA complex assembly;1.2079894005288e-18!GO:0044265;cellular macromolecule catabolic process;1.52227081297009e-18!GO:0051603;proteolysis involved in cellular protein catabolic process;1.99176451617697e-18!GO:0008134;transcription factor binding;2.6400687625727e-18!GO:0006512;ubiquitin cycle;2.96277928610134e-18!GO:0019941;modification-dependent protein catabolic process;3.83697076243936e-18!GO:0043632;modification-dependent macromolecule catabolic process;3.83697076243936e-18!GO:0032553;ribonucleotide binding;5.78158743533947e-18!GO:0032555;purine ribonucleotide binding;5.78158743533947e-18!GO:0044257;cellular protein catabolic process;6.15569797903929e-18!GO:0006511;ubiquitin-dependent protein catabolic process;6.17566563031503e-18!GO:0017076;purine nucleotide binding;9.28270089229943e-18!GO:0009719;response to endogenous stimulus;1.12159444197607e-17!GO:0043285;biopolymer catabolic process;1.32360631623833e-17!GO:0012505;endomembrane system;4.22843919922498e-17!GO:0005746;mitochondrial respiratory chain;5.14571693299588e-17!GO:0005730;nucleolus;5.97520231585848e-17!GO:0006457;protein folding;3.58411384370089e-16!GO:0009057;macromolecule catabolic process;4.52549198913543e-16!GO:0000502;proteasome complex (sensu Eukaryota);4.5421199746013e-16!GO:0008135;translation factor activity, nucleic acid binding;5.75934353066749e-16!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;8.67532472104893e-16!GO:0048770;pigment granule;9.51813459788913e-16!GO:0042470;melanosome;9.51813459788913e-16!GO:0005524;ATP binding;1.67053105226009e-15!GO:0050794;regulation of cellular process;1.78274726358562e-15!GO:0006605;protein targeting;2.117765792047e-15!GO:0032559;adenyl ribonucleotide binding;2.30592114351851e-15!GO:0044248;cellular catabolic process;2.72436682291902e-15!GO:0005761;mitochondrial ribosome;2.73501082678431e-15!GO:0000313;organellar ribosome;2.73501082678431e-15!GO:0030163;protein catabolic process;3.72194036585925e-15!GO:0005635;nuclear envelope;4.70456008947581e-15!GO:0030554;adenyl nucleotide binding;5.05866757324191e-15!GO:0044453;nuclear membrane part;6.33338066929287e-15!GO:0006325;establishment and/or maintenance of chromatin architecture;6.64078205408026e-15!GO:0050136;NADH dehydrogenase (quinone) activity;7.09217914735864e-15!GO:0003954;NADH dehydrogenase activity;7.09217914735864e-15!GO:0008137;NADH dehydrogenase (ubiquinone) activity;7.09217914735864e-15!GO:0012501;programmed cell death;8.11811031248247e-15!GO:0006915;apoptosis;1.13825731832691e-14!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.78880478767941e-14!GO:0031965;nuclear membrane;1.78880478767941e-14!GO:0006323;DNA packaging;2.87941941143819e-14!GO:0051726;regulation of cell cycle;4.33952445414171e-14!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;5.4009435124751e-14!GO:0000074;regulation of progression through cell cycle;5.41373516502327e-14!GO:0006366;transcription from RNA polymerase II promoter;5.65659347354298e-14!GO:0000785;chromatin;8.50558829260203e-14!GO:0005783;endoplasmic reticulum;8.67664881054981e-14!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.12646720024158e-13!GO:0042254;ribosome biogenesis and assembly;1.41844985330768e-13!GO:0000398;nuclear mRNA splicing, via spliceosome;2.17338650548446e-13!GO:0000375;RNA splicing, via transesterification reactions;2.17338650548446e-13!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;2.17338650548446e-13!GO:0051186;cofactor metabolic process;2.40342579325768e-13!GO:0042775;organelle ATP synthesis coupled electron transport;2.4125138961233e-13!GO:0042773;ATP synthesis coupled electron transport;2.4125138961233e-13!GO:0043412;biopolymer modification;3.13333260988649e-13!GO:0008219;cell death;5.8096975521127e-13!GO:0016265;death;5.8096975521127e-13!GO:0030964;NADH dehydrogenase complex (quinone);8.54945928511314e-13!GO:0045271;respiratory chain complex I;8.54945928511314e-13!GO:0005747;mitochondrial respiratory chain complex I;8.54945928511314e-13!GO:0005643;nuclear pore;2.14611302549771e-12!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;2.26198336578726e-12!GO:0016887;ATPase activity;2.52102035366788e-12!GO:0015630;microtubule cytoskeleton;2.71441386095409e-12!GO:0006913;nucleocytoplasmic transport;4.73568027521367e-12!GO:0048193;Golgi vesicle transport;5.55365352639963e-12!GO:0051082;unfolded protein binding;5.55365352639963e-12!GO:0006333;chromatin assembly or disassembly;6.5899237933612e-12!GO:0065004;protein-DNA complex assembly;6.69707979361086e-12!GO:0044432;endoplasmic reticulum part;8.6667634353756e-12!GO:0003743;translation initiation factor activity;9.02777121800204e-12!GO:0016604;nuclear body;1.06752762344363e-11!GO:0009055;electron carrier activity;1.21450103343542e-11!GO:0051169;nuclear transport;1.39436059466677e-11!GO:0006413;translational initiation;1.89479966142449e-11!GO:0048523;negative regulation of cellular process;3.04904204202e-11!GO:0042623;ATPase activity, coupled;3.16193097212597e-11!GO:0006464;protein modification process;3.27663318713308e-11!GO:0043687;post-translational protein modification;3.35354762918203e-11!GO:0003712;transcription cofactor activity;3.40748992283291e-11!GO:0008639;small protein conjugating enzyme activity;5.48246125972737e-11!GO:0006461;protein complex assembly;6.41128000828599e-11!GO:0006399;tRNA metabolic process;6.51099399087181e-11!GO:0004386;helicase activity;9.07813676742424e-11!GO:0005819;spindle;9.23108126094338e-11!GO:0004842;ubiquitin-protein ligase activity;1.06490796970699e-10!GO:0006446;regulation of translational initiation;1.4051283349308e-10!GO:0050657;nucleic acid transport;1.49151581580676e-10!GO:0051236;establishment of RNA localization;1.49151581580676e-10!GO:0050658;RNA transport;1.49151581580676e-10!GO:0005794;Golgi apparatus;1.49151581580676e-10!GO:0006403;RNA localization;1.6294731115571e-10!GO:0016879;ligase activity, forming carbon-nitrogen bonds;2.04176739999128e-10!GO:0006732;coenzyme metabolic process;2.22428832735408e-10!GO:0019787;small conjugating protein ligase activity;2.59834599342434e-10!GO:0006334;nucleosome assembly;2.68984149438616e-10!GO:0050789;regulation of biological process;5.05356758953047e-10!GO:0006261;DNA-dependent DNA replication;7.79380962938053e-10!GO:0031497;chromatin assembly;1.19725558207107e-09!GO:0042981;regulation of apoptosis;1.21499032549834e-09!GO:0048519;negative regulation of biological process;1.22398627325997e-09!GO:0046930;pore complex;1.25085298928487e-09!GO:0043067;regulation of programmed cell death;1.31610647575629e-09!GO:0065002;intracellular protein transport across a membrane;3.46346818425711e-09!GO:0016881;acid-amino acid ligase activity;4.24689088616097e-09!GO:0000775;chromosome, pericentric region;4.24689088616097e-09!GO:0016607;nuclear speck;4.39245109794414e-09!GO:0019222;regulation of metabolic process;4.55593338288588e-09!GO:0008026;ATP-dependent helicase activity;5.67132527913933e-09!GO:0042175;nuclear envelope-endoplasmic reticulum network;5.90354929219034e-09!GO:0006364;rRNA processing;9.36098831323334e-09!GO:0009056;catabolic process;9.91247153692745e-09!GO:0007005;mitochondrion organization and biogenesis;9.96790085817096e-09!GO:0008565;protein transporter activity;1.02002290103888e-08!GO:0017038;protein import;1.02080851473012e-08!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.08295770321467e-08!GO:0005789;endoplasmic reticulum membrane;1.22393990147182e-08!GO:0043566;structure-specific DNA binding;1.30435037695177e-08!GO:0043069;negative regulation of programmed cell death;1.30435037695177e-08!GO:0051028;mRNA transport;1.51291916102976e-08!GO:0016192;vesicle-mediated transport;1.60237725963504e-08!GO:0016072;rRNA metabolic process;2.11272291572373e-08!GO:0030532;small nuclear ribonucleoprotein complex;2.84836331531649e-08!GO:0043066;negative regulation of apoptosis;2.87651681863889e-08!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;4.27953551393198e-08!GO:0004812;aminoacyl-tRNA ligase activity;4.27953551393198e-08!GO:0016875;ligase activity, forming carbon-oxygen bonds;4.27953551393198e-08!GO:0006916;anti-apoptosis;4.61367561591881e-08!GO:0032446;protein modification by small protein conjugation;4.78315668452485e-08!GO:0005813;centrosome;5.67553257776694e-08!GO:0007051;spindle organization and biogenesis;8.1353877053632e-08!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;8.35338838863034e-08!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;9.00074741187536e-08!GO:0016567;protein ubiquitination;9.92656341959871e-08!GO:0043038;amino acid activation;1.06456787762375e-07!GO:0006418;tRNA aminoacylation for protein translation;1.06456787762375e-07!GO:0043039;tRNA aminoacylation;1.06456787762375e-07!GO:0051246;regulation of protein metabolic process;1.2951386561328e-07!GO:0016779;nucleotidyltransferase activity;1.44774977402664e-07!GO:0005815;microtubule organizing center;1.44774977402664e-07!GO:0016568;chromatin modification;1.5423643774652e-07!GO:0006357;regulation of transcription from RNA polymerase II promoter;1.61612179848349e-07!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;1.66165818790981e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.8020786002636e-07!GO:0003697;single-stranded DNA binding;1.82958313377489e-07!GO:0051188;cofactor biosynthetic process;1.84014189818833e-07!GO:0009060;aerobic respiration;1.93817742196837e-07!GO:0005667;transcription factor complex;2.84173467399247e-07!GO:0005793;ER-Golgi intermediate compartment;3.20067092927353e-07!GO:0005839;proteasome core complex (sensu Eukaryota);3.71863498487001e-07!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;4.04858016142404e-07!GO:0003924;GTPase activity;4.2968065298842e-07!GO:0007249;I-kappaB kinase/NF-kappaB cascade;5.12866052264053e-07!GO:0043623;cellular protein complex assembly;5.9008494871872e-07!GO:0051329;interphase of mitotic cell cycle;6.05613587306128e-07!GO:0030120;vesicle coat;7.24369045615192e-07!GO:0030662;coated vesicle membrane;7.24369045615192e-07!GO:0048475;coated membrane;7.93746994862335e-07!GO:0030117;membrane coat;7.93746994862335e-07!GO:0016740;transferase activity;9.33560317734019e-07!GO:0000245;spliceosome assembly;9.53325625098366e-07!GO:0031323;regulation of cellular metabolic process;1.03506039944414e-06!GO:0007010;cytoskeleton organization and biogenesis;1.36843644986471e-06!GO:0045333;cellular respiration;1.48082576484053e-06!GO:0051170;nuclear import;1.53541088109937e-06!GO:0016564;transcription repressor activity;1.56828940309479e-06!GO:0004298;threonine endopeptidase activity;1.56828940309479e-06!GO:0005657;replication fork;1.61649348702746e-06!GO:0009259;ribonucleotide metabolic process;1.61680112087399e-06!GO:0006350;transcription;1.81238406005564e-06!GO:0015986;ATP synthesis coupled proton transport;1.83908555526297e-06!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.83908555526297e-06!GO:0051325;interphase;1.96666521539617e-06!GO:0006163;purine nucleotide metabolic process;2.08352982136196e-06!GO:0016787;hydrolase activity;2.20508518938266e-06!GO:0006888;ER to Golgi vesicle-mediated transport;2.26321343389103e-06!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.32164404368075e-06!GO:0031324;negative regulation of cellular metabolic process;2.42099644549443e-06!GO:0006099;tricarboxylic acid cycle;4.0906695830323e-06!GO:0046356;acetyl-CoA catabolic process;4.0906695830323e-06!GO:0006606;protein import into nucleus;4.37985093723205e-06!GO:0065007;biological regulation;4.48415892854422e-06!GO:0042802;identical protein binding;4.54166101957826e-06!GO:0019829;cation-transporting ATPase activity;4.83402740540381e-06!GO:0000151;ubiquitin ligase complex;5.83145061680004e-06!GO:0009150;purine ribonucleotide metabolic process;5.93528206645613e-06!GO:0016563;transcription activator activity;5.95905947705067e-06!GO:0006084;acetyl-CoA metabolic process;6.97622128010419e-06!GO:0045259;proton-transporting ATP synthase complex;7.03664170161558e-06!GO:0009108;coenzyme biosynthetic process;7.65178297928078e-06!GO:0006164;purine nucleotide biosynthetic process;7.67865455675599e-06!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;7.96927042739493e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;7.96927042739493e-06!GO:0005768;endosome;8.12548150450311e-06!GO:0009260;ribonucleotide biosynthetic process;8.1814623784459e-06!GO:0007017;microtubule-based process;8.34898435395282e-06!GO:0045786;negative regulation of progression through cell cycle;8.46663183350365e-06!GO:0000786;nucleosome;8.58078755337017e-06!GO:0016491;oxidoreductase activity;9.11093853405975e-06!GO:0005762;mitochondrial large ribosomal subunit;1.0166859778583e-05!GO:0000315;organellar large ribosomal subunit;1.0166859778583e-05!GO:0007059;chromosome segregation;1.11892504689172e-05!GO:0015078;hydrogen ion transmembrane transporter activity;1.14848495926038e-05!GO:0009109;coenzyme catabolic process;1.22695768492894e-05!GO:0008094;DNA-dependent ATPase activity;1.26719650752346e-05!GO:0048522;positive regulation of cellular process;1.3130793684042e-05!GO:0005874;microtubule;1.41308512055625e-05!GO:0003713;transcription coactivator activity;1.4532071027203e-05!GO:0009141;nucleoside triphosphate metabolic process;1.62357670849048e-05!GO:0006793;phosphorus metabolic process;1.75485312650839e-05!GO:0006796;phosphate metabolic process;1.75485312650839e-05!GO:0046034;ATP metabolic process;1.80940670027102e-05!GO:0007088;regulation of mitosis;1.99933458382436e-05!GO:0005525;GTP binding;2.1218114278505e-05!GO:0009152;purine ribonucleotide biosynthetic process;2.1218114278505e-05!GO:0009199;ribonucleoside triphosphate metabolic process;2.1218114278505e-05!GO:0003714;transcription corepressor activity;2.38041223627309e-05!GO:0051187;cofactor catabolic process;2.38041223627309e-05!GO:0006754;ATP biosynthetic process;2.42041222314207e-05!GO:0006753;nucleoside phosphate metabolic process;2.42041222314207e-05!GO:0007243;protein kinase cascade;2.52637780142166e-05!GO:0009892;negative regulation of metabolic process;2.57556647775504e-05!GO:0003690;double-stranded DNA binding;2.63786349589323e-05!GO:0000776;kinetochore;2.67476983461497e-05!GO:0010468;regulation of gene expression;2.67476983461497e-05!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.67760630301905e-05!GO:0000075;cell cycle checkpoint;2.73112485962428e-05!GO:0009205;purine ribonucleoside triphosphate metabolic process;3.03247731665008e-05!GO:0009144;purine nucleoside triphosphate metabolic process;3.03247731665008e-05!GO:0003682;chromatin binding;3.65508131680659e-05!GO:0051427;hormone receptor binding;3.68968493156091e-05!GO:0009142;nucleoside triphosphate biosynthetic process;3.76455578825376e-05!GO:0009201;ribonucleoside triphosphate biosynthetic process;3.76455578825376e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;3.79385702874784e-05!GO:0003724;RNA helicase activity;3.92213378142375e-05!GO:0000226;microtubule cytoskeleton organization and biogenesis;3.94710995186996e-05!GO:0006613;cotranslational protein targeting to membrane;4.06380765664731e-05!GO:0051168;nuclear export;4.36851148513469e-05!GO:0016469;proton-transporting two-sector ATPase complex;4.80833936600805e-05!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;5.47831012511948e-05!GO:0009145;purine nucleoside triphosphate biosynthetic process;5.47831012511948e-05!GO:0051052;regulation of DNA metabolic process;5.66925395839114e-05!GO:0016481;negative regulation of transcription;5.91612229750089e-05!GO:0032774;RNA biosynthetic process;6.52414814343888e-05!GO:0043021;ribonucleoprotein binding;7.18305718348739e-05!GO:0009117;nucleotide metabolic process;7.37210462152817e-05!GO:0006302;double-strand break repair;7.43583579390783e-05!GO:0035257;nuclear hormone receptor binding;7.90257470510286e-05!GO:0015631;tubulin binding;8.34402116363679e-05!GO:0006351;transcription, DNA-dependent;8.37851426118401e-05!GO:0006752;group transfer coenzyme metabolic process;8.49380882506136e-05!GO:0045893;positive regulation of transcription, DNA-dependent;9.39976886389711e-05!GO:0000314;organellar small ribosomal subunit;9.39976886389711e-05!GO:0005763;mitochondrial small ribosomal subunit;9.39976886389711e-05!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;9.71115487209034e-05!GO:0016853;isomerase activity;9.8803726671968e-05!GO:0003899;DNA-directed RNA polymerase activity;0.000114142531936676!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000144491795657887!GO:0045941;positive regulation of transcription;0.000165393820931623!GO:0016363;nuclear matrix;0.0001685608551459!GO:0016310;phosphorylation;0.000175108344325071!GO:0003702;RNA polymerase II transcription factor activity;0.000178422361211755!GO:0006414;translational elongation;0.000180501616609721!GO:0006091;generation of precursor metabolites and energy;0.000183615749287507!GO:0048471;perinuclear region of cytoplasm;0.00018742816620753!GO:0008033;tRNA processing;0.000203213934904887!GO:0044431;Golgi apparatus part;0.000206334387599971!GO:0005788;endoplasmic reticulum lumen;0.000232271121141705!GO:0003729;mRNA binding;0.000275246003599772!GO:0003684;damaged DNA binding;0.000278955306368266!GO:0007052;mitotic spindle organization and biogenesis;0.000289241323685518!GO:0032561;guanyl ribonucleotide binding;0.000303022325636764!GO:0019001;guanyl nucleotide binding;0.000303022325636764!GO:0005048;signal sequence binding;0.000320032655754575!GO:0006275;regulation of DNA replication;0.000358130079211386!GO:0031252;leading edge;0.000367059755343765!GO:0005798;Golgi-associated vesicle;0.000368087686965342!GO:0007264;small GTPase mediated signal transduction;0.00037672918008358!GO:0005770;late endosome;0.000403986496856101!GO:0044440;endosomal part;0.000404490855077092!GO:0010008;endosome membrane;0.000404490855077092!GO:0051252;regulation of RNA metabolic process;0.000410105733481752!GO:0006612;protein targeting to membrane;0.000435383568448826!GO:0048468;cell development;0.000436971378829655!GO:0000922;spindle pole;0.000450881428098684!GO:0046483;heterocycle metabolic process;0.000485433859097507!GO:0009967;positive regulation of signal transduction;0.00052860955108809!GO:0008654;phospholipid biosynthetic process;0.00054075194433386!GO:0015077;monovalent inorganic cation transmembrane transporter activity;0.000553196160011505!GO:0006402;mRNA catabolic process;0.00057242403891032!GO:0043681;protein import into mitochondrion;0.000600040354727681!GO:0006950;response to stress;0.000639798445221143!GO:0006839;mitochondrial transport;0.000713695853394327!GO:0008186;RNA-dependent ATPase activity;0.000743398033384063!GO:0045449;regulation of transcription;0.000743398033384063!GO:0050662;coenzyme binding;0.000766107797372418!GO:0045454;cell redox homeostasis;0.00078010991478269!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000802996574814532!GO:0019867;outer membrane;0.000867287696732072!GO:0031988;membrane-bound vesicle;0.000880461822294391!GO:0030036;actin cytoskeleton organization and biogenesis;0.000881333936047025!GO:0005876;spindle microtubule;0.000895052705061713!GO:0008250;oligosaccharyl transferase complex;0.000948362439477725!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000959801067272974!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000961412423904057!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000961831975292614!GO:0016023;cytoplasmic membrane-bound vesicle;0.000991381426552137!GO:0031968;organelle outer membrane;0.00104018389756422!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00106384570347078!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00106384570347078!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00106384570347078!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00109094265940626!GO:0032508;DNA duplex unwinding;0.00109094265940626!GO:0032392;DNA geometric change;0.00109094265940626!GO:0004576;oligosaccharyl transferase activity;0.00109164244344927!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00112652834043753!GO:0065009;regulation of a molecular function;0.0011571871626475!GO:0051920;peroxiredoxin activity;0.00125479310368846!GO:0006401;RNA catabolic process;0.00125868097537978!GO:0005637;nuclear inner membrane;0.00126107685874302!GO:0016859;cis-trans isomerase activity;0.00127511104358689!GO:0006626;protein targeting to mitochondrion;0.00127511104358689!GO:0005885;Arp2/3 protein complex;0.0012920890296781!GO:0005769;early endosome;0.00131930160504422!GO:0007093;mitotic cell cycle checkpoint;0.0013630961048519!GO:0003677;DNA binding;0.00138100573688769!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00138542046368574!GO:0000059;protein import into nucleus, docking;0.00139256517791422!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00148487991160217!GO:0030119;AP-type membrane coat adaptor complex;0.00149971687344687!GO:0030867;rough endoplasmic reticulum membrane;0.00164871956044649!GO:0030132;clathrin coat of coated pit;0.00168709274300531!GO:0003746;translation elongation factor activity;0.00175018903073255!GO:0001726;ruffle;0.00179285093967595!GO:0043488;regulation of mRNA stability;0.00186521775065006!GO:0043487;regulation of RNA stability;0.00186521775065006!GO:0009112;nucleobase metabolic process;0.0018659697871985!GO:0004004;ATP-dependent RNA helicase activity;0.00187514135733345!GO:0000082;G1/S transition of mitotic cell cycle;0.00190010508278803!GO:0016741;transferase activity, transferring one-carbon groups;0.00193715835761845!GO:0000139;Golgi membrane;0.0020490765404156!GO:0003678;DNA helicase activity;0.0020681900015119!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00206964247896659!GO:0008361;regulation of cell size;0.00207638626200046!GO:0031982;vesicle;0.00219279216355775!GO:0006891;intra-Golgi vesicle-mediated transport;0.00224079467892527!GO:0030118;clathrin coat;0.00233499633699964!GO:0008139;nuclear localization sequence binding;0.00238561406453848!GO:0005684;U2-dependent spliceosome;0.00243801313069221!GO:0006268;DNA unwinding during replication;0.00247415662584701!GO:0007006;mitochondrial membrane organization and biogenesis;0.00260218463372294!GO:0006289;nucleotide-excision repair;0.00264175311447784!GO:0019843;rRNA binding;0.00271559564106533!GO:0005773;vacuole;0.00273788980595579!GO:0005741;mitochondrial outer membrane;0.00274342035442674!GO:0006284;base-excision repair;0.00277227927613615!GO:0004674;protein serine/threonine kinase activity;0.00279281832776975!GO:0016049;cell growth;0.00279356609575585!GO:0006405;RNA export from nucleus;0.00279988944938499!GO:0006310;DNA recombination;0.00282667630852785!GO:0048518;positive regulation of biological process;0.00293441877596796!GO:0015980;energy derivation by oxidation of organic compounds;0.00307428632048354!GO:0008168;methyltransferase activity;0.00308755979570854!GO:0031410;cytoplasmic vesicle;0.00315425641861512!GO:0030131;clathrin adaptor complex;0.00327974455776693!GO:0000819;sister chromatid segregation;0.00330875128193879!GO:0030031;cell projection biogenesis;0.00336973660277912!GO:0018196;peptidyl-asparagine modification;0.00340842709214666!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00340842709214666!GO:0006355;regulation of transcription, DNA-dependent;0.00357954708054882!GO:0004527;exonuclease activity;0.00357992113234631!GO:0019899;enzyme binding;0.00359204932000575!GO:0044452;nucleolar part;0.00363753220776149!GO:0000070;mitotic sister chromatid segregation;0.0036675863957589!GO:0048500;signal recognition particle;0.00375694761478174!GO:0030663;COPI coated vesicle membrane;0.00391076258417021!GO:0030126;COPI vesicle coat;0.00391076258417021!GO:0033116;ER-Golgi intermediate compartment membrane;0.00393857698050651!GO:0031072;heat shock protein binding;0.00409277681913157!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00413957409601703!GO:0015002;heme-copper terminal oxidase activity;0.00413957409601703!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00413957409601703!GO:0004129;cytochrome-c oxidase activity;0.00413957409601703!GO:0008234;cysteine-type peptidase activity;0.00422310103744181!GO:0009116;nucleoside metabolic process;0.0042852290864861!GO:0051789;response to protein stimulus;0.00433839180071887!GO:0006986;response to unfolded protein;0.00433839180071887!GO:0001558;regulation of cell growth;0.00448039690639911!GO:0005905;coated pit;0.00450937955612726!GO:0006611;protein export from nucleus;0.00454192011463361!GO:0000792;heterochromatin;0.00461356727344531!GO:0030658;transport vesicle membrane;0.00464554382111173!GO:0048487;beta-tubulin binding;0.00471518699873238!GO:0008637;apoptotic mitochondrial changes;0.00480637075665079!GO:0008092;cytoskeletal protein binding;0.0048554755546317!GO:0004518;nuclease activity;0.00486103410975328!GO:0006352;transcription initiation;0.00523194246505489!GO:0051540;metal cluster binding;0.00536897006066325!GO:0051536;iron-sulfur cluster binding;0.00536897006066325!GO:0016584;nucleosome positioning;0.00536897006066325!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00538542347340728!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.00562462540212652!GO:0006607;NLS-bearing substrate import into nucleus;0.00589915311221659!GO:0006979;response to oxidative stress;0.00598554748706266!GO:0030880;RNA polymerase complex;0.00602375192556884!GO:0000323;lytic vacuole;0.00602375192556884!GO:0005764;lysosome;0.00602375192556884!GO:0006417;regulation of translation;0.00626047086396!GO:0000049;tRNA binding;0.00626081283828991!GO:0006520;amino acid metabolic process;0.00636618848494012!GO:0045892;negative regulation of transcription, DNA-dependent;0.00638586073978705!GO:0006383;transcription from RNA polymerase III promoter;0.00639309251653562!GO:0003711;transcription elongation regulator activity;0.00640916102034817!GO:0030029;actin filament-based process;0.00655004417643779!GO:0008017;microtubule binding;0.00674571579073737!GO:0016628;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;0.00688096491087561!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00697096593877202!GO:0031970;organelle envelope lumen;0.00699285158743896!GO:0051101;regulation of DNA binding;0.00710408638754258!GO:0005758;mitochondrial intermembrane space;0.00716141708677626!GO:0046983;protein dimerization activity;0.00730656879563829!GO:0005791;rough endoplasmic reticulum;0.0074663407589375!GO:0031124;mRNA 3'-end processing;0.00770834195518746!GO:0008312;7S RNA binding;0.0079280351226519!GO:0031529;ruffle organization and biogenesis;0.00799121207902167!GO:0030137;COPI-coated vesicle;0.00801291245343732!GO:0030133;transport vesicle;0.00808034520586314!GO:0042770;DNA damage response, signal transduction;0.0083273461600414!GO:0043596;nuclear replication fork;0.0083273461600414!GO:0035258;steroid hormone receptor binding;0.00847314522613189!GO:0048037;cofactor binding;0.00854576764098782!GO:0016044;membrane organization and biogenesis;0.00864868632130989!GO:0006270;DNA replication initiation;0.00868189990716506!GO:0000096;sulfur amino acid metabolic process;0.00870437901109125!GO:0043624;cellular protein complex disassembly;0.0088744804237355!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00890208408960025!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00890208408960025!GO:0043022;ribosome binding;0.0090087044429297!GO:0019752;carboxylic acid metabolic process;0.00935779145162283!GO:0030127;COPII vesicle coat;0.0094965361909915!GO:0012507;ER to Golgi transport vesicle membrane;0.0094965361909915!GO:0000725;recombinational repair;0.0094965361909915!GO:0000724;double-strand break repair via homologous recombination;0.0094965361909915!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.00963487438643656!GO:0007346;regulation of progression through mitotic cell cycle;0.00984822453069502!GO:0030660;Golgi-associated vesicle membrane;0.00987843881196204!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0099040141555495!GO:0030134;ER to Golgi transport vesicle;0.00992307747722295!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00992307747722295!GO:0043284;biopolymer biosynthetic process;0.0099320203803147!GO:0051656;establishment of organelle localization;0.0102621771129909!GO:0051287;NAD binding;0.0103143127342291!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0103143127342291!GO:0045047;protein targeting to ER;0.0103143127342291!GO:0005832;chaperonin-containing T-complex;0.0103680987033609!GO:0006082;organic acid metabolic process;0.0104094608938472!GO:0051087;chaperone binding;0.010609179352287!GO:0030176;integral to endoplasmic reticulum membrane;0.0106105877991752!GO:0016272;prefoldin complex;0.0106307197667644!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.0106307197667644!GO:0015399;primary active transmembrane transporter activity;0.0106307197667644!GO:0046966;thyroid hormone receptor binding;0.0110527421670487!GO:0008632;apoptotic program;0.0112814949016893!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.0113362974724315!GO:0000428;DNA-directed RNA polymerase complex;0.0113362974724315!GO:0000086;G2/M transition of mitotic cell cycle;0.0113736856011365!GO:0005853;eukaryotic translation elongation factor 1 complex;0.0114052852652527!GO:0005663;DNA replication factor C complex;0.0115823286714169!GO:0016251;general RNA polymerase II transcription factor activity;0.0118040679114306!GO:0019904;protein domain specific binding;0.0122024125306504!GO:0031577;spindle checkpoint;0.0122790363880139!GO:0043065;positive regulation of apoptosis;0.0123089789634454!GO:0051338;regulation of transferase activity;0.0123725989151029!GO:0009893;positive regulation of metabolic process;0.0124753178792716!GO:0000910;cytokinesis;0.0126151452139635!GO:0008601;protein phosphatase type 2A regulator activity;0.0126994806334467!GO:0006118;electron transport;0.013235896918003!GO:0033673;negative regulation of kinase activity;0.0135980847483866!GO:0006469;negative regulation of protein kinase activity;0.0135980847483866!GO:0032984;macromolecular complex disassembly;0.0136409709484221!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0138332927667415!GO:0005856;cytoskeleton;0.0146348549393837!GO:0043068;positive regulation of programmed cell death;0.0148348726611299!GO:0006144;purine base metabolic process;0.0148755373761405!GO:0042393;histone binding;0.0150409954366955!GO:0051539;4 iron, 4 sulfur cluster binding;0.0153593850768213!GO:0031625;ubiquitin protein ligase binding;0.0156966505630404!GO:0030032;lamellipodium biogenesis;0.0158303895058316!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0159271814437409!GO:0006376;mRNA splice site selection;0.0159671836304254!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0159671836304254!GO:0043414;biopolymer methylation;0.0162167531060435!GO:0019783;small conjugating protein-specific protease activity;0.0164287596795335!GO:0008022;protein C-terminus binding;0.0166934392170437!GO:0006338;chromatin remodeling;0.0167802574955898!GO:0008283;cell proliferation;0.0168254794648894!GO:0016408;C-acyltransferase activity;0.017030199708643!GO:0043189;H4/H2A histone acetyltransferase complex;0.0170872562082701!GO:0051348;negative regulation of transferase activity;0.0171221581491429!GO:0000228;nuclear chromosome;0.0172297386345379!GO:0046982;protein heterodimerization activity;0.0172778165865795!GO:0046467;membrane lipid biosynthetic process;0.0177450438461154!GO:0051053;negative regulation of DNA metabolic process;0.0177745916794261!GO:0043130;ubiquitin binding;0.0178238659126737!GO:0032182;small conjugating protein binding;0.0178238659126737!GO:0043601;nuclear replisome;0.0182820809334859!GO:0030894;replisome;0.0182820809334859!GO:0004029;aldehyde dehydrogenase (NAD) activity;0.0185425219683617!GO:0009081;branched chain family amino acid metabolic process;0.0186201472482323!GO:0050790;regulation of catalytic activity;0.0187329131412361!GO:0031123;RNA 3'-end processing;0.0194370591842568!GO:0006595;polyamine metabolic process;0.0195585056634502!GO:0006378;mRNA polyadenylation;0.0197997811508835!GO:0045334;clathrin-coated endocytic vesicle;0.020229078494321!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0202407049014814!GO:0030521;androgen receptor signaling pathway;0.0206648941857096!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0208487739319071!GO:0051098;regulation of binding;0.0209841387263925!GO:0032259;methylation;0.0210176225623638!GO:0016197;endosome transport;0.021109180050387!GO:0016126;sterol biosynthetic process;0.0211225857177921!GO:0031326;regulation of cellular biosynthetic process;0.0211773915159845!GO:0005875;microtubule associated complex;0.0219497889530127!GO:0009451;RNA modification;0.0219871974745971!GO:0031406;carboxylic acid binding;0.0221700938588672!GO:0000152;nuclear ubiquitin ligase complex;0.0222380005689321!GO:0009303;rRNA transcription;0.0222428892559946!GO:0004843;ubiquitin-specific protease activity;0.0230099372772733!GO:0043549;regulation of kinase activity;0.0234323962313942!GO:0046474;glycerophospholipid biosynthetic process;0.0238680475947417!GO:0000123;histone acetyltransferase complex;0.0238878332558111!GO:0009165;nucleotide biosynthetic process;0.0240184748024098!GO:0008408;3'-5' exonuclease activity;0.0241407334671625!GO:0043241;protein complex disassembly;0.0243207660673409!GO:0017166;vinculin binding;0.0248300044710886!GO:0000178;exosome (RNase complex);0.0251018488098687!GO:0006354;RNA elongation;0.0256075595431369!GO:0015992;proton transport;0.0257786151074343!GO:0006818;hydrogen transport;0.0260531140296698!GO:0001836;release of cytochrome c from mitochondria;0.0262718363619476!GO:0030125;clathrin vesicle coat;0.0263402286017918!GO:0030665;clathrin coated vesicle membrane;0.0263402286017918!GO:0000209;protein polyubiquitination;0.0263402286017918!GO:0031570;DNA integrity checkpoint;0.0265192663438338!GO:0004300;enoyl-CoA hydratase activity;0.0265874510051252!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.026601548962757!GO:0016616;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;0.026601548962757!GO:0007265;Ras protein signal transduction;0.0266195654853052!GO:0045792;negative regulation of cell size;0.027258480036764!GO:0040008;regulation of growth;0.0274127127405134!GO:0005669;transcription factor TFIID complex;0.0282934186445619!GO:0006733;oxidoreduction coenzyme metabolic process;0.02873910861424!GO:0008536;Ran GTPase binding;0.0288339643036668!GO:0030865;cortical cytoskeleton organization and biogenesis;0.0291067681971702!GO:0030308;negative regulation of cell growth;0.0298284696424417!GO:0047115;trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity;0.0298284696424417!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0298284696424417!GO:0006519;amino acid and derivative metabolic process;0.0298599107135153!GO:0005938;cell cortex;0.0299978968017997!GO:0016790;thiolester hydrolase activity;0.0304008393655229!GO:0006672;ceramide metabolic process;0.0305460998537343!GO:0009119;ribonucleoside metabolic process;0.0308162625283528!GO:0035267;NuA4 histone acetyltransferase complex;0.0314841118527559!GO:0030911;TPR domain binding;0.0320576661653934!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0320782721763024!GO:0010257;NADH dehydrogenase complex assembly;0.0320782721763024!GO:0033108;mitochondrial respiratory chain complex assembly;0.0320782721763024!GO:0045045;secretory pathway;0.0321527115239722!GO:0016791;phosphoric monoester hydrolase activity;0.0325646977499469!GO:0008610;lipid biosynthetic process;0.0327925401248653!GO:0000118;histone deacetylase complex;0.032856961381347!GO:0000339;RNA cap binding;0.032947109623077!GO:0004221;ubiquitin thiolesterase activity;0.0332199157077699!GO:0046489;phosphoinositide biosynthetic process;0.0333279515194854!GO:0030128;clathrin coat of endocytic vesicle;0.0334099534632885!GO:0030669;clathrin-coated endocytic vesicle membrane;0.0334099534632885!GO:0030122;AP-2 adaptor complex;0.0334099534632885!GO:0008156;negative regulation of DNA replication;0.034273460724448!GO:0009411;response to UV;0.0344282293251278!GO:0031371;ubiquitin conjugating enzyme complex;0.0349158166654659!GO:0043154;negative regulation of caspase activity;0.0350717309899634!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0353008030987846!GO:0032507;maintenance of cellular protein localization;0.0353620422261179!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0354666196375926!GO:0006650;glycerophospholipid metabolic process;0.0357136501599883!GO:0005092;GDP-dissociation inhibitor activity;0.0359594407776055!GO:0044262;cellular carbohydrate metabolic process;0.0360174646755495!GO:0006740;NADPH regeneration;0.0362881694837641!GO:0006098;pentose-phosphate shunt;0.0362881694837641!GO:0033170;DNA-protein loading ATPase activity;0.0366184214910265!GO:0003689;DNA clamp loader activity;0.0366184214910265!GO:0046519;sphingoid metabolic process;0.0367280328525414!GO:0031325;positive regulation of cellular metabolic process;0.0369300870753688!GO:0008180;signalosome;0.0370537832182521!GO:0007021;tubulin folding;0.0374390136622235!GO:0022890;inorganic cation transmembrane transporter activity;0.0374988039647541!GO:0007050;cell cycle arrest;0.03795814370734!GO:0045859;regulation of protein kinase activity;0.03795814370734!GO:0005083;small GTPase regulator activity;0.0380661981792727!GO:0016311;dephosphorylation;0.0380925387722424!GO:0005784;translocon complex;0.0380925387722424!GO:0007242;intracellular signaling cascade;0.0385320607181735!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0386251837060525!GO:0043492;ATPase activity, coupled to movement of substances;0.0390345561765586!GO:0007094;mitotic cell cycle spindle assembly checkpoint;0.0390345561765586!GO:0046588;negative regulation of calcium-dependent cell-cell adhesion;0.0390345561765586!GO:0046586;regulation of calcium-dependent cell-cell adhesion;0.0390345561765586!GO:0008652;amino acid biosynthetic process;0.0390345561765586!GO:0032200;telomere organization and biogenesis;0.0390345561765586!GO:0000723;telomere maintenance;0.0390345561765586!GO:0008538;proteasome activator activity;0.0393931939641531!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0396482840716443!GO:0006779;porphyrin biosynthetic process;0.0396482840716443!GO:0033014;tetrapyrrole biosynthetic process;0.0396482840716443!GO:0004003;ATP-dependent DNA helicase activity;0.0396718315983042!GO:0046112;nucleobase biosynthetic process;0.0401656987271681!GO:0006400;tRNA modification;0.0404854874311095!GO:0046822;regulation of nucleocytoplasmic transport;0.0406229894159397!GO:0022411;cellular component disassembly;0.041216095664248!GO:0005652;nuclear lamina;0.0418086291942775!GO:0009889;regulation of biosynthetic process;0.0418368017199308!GO:0030518;steroid hormone receptor signaling pathway;0.0418770776217629!GO:0004239;methionyl aminopeptidase activity;0.0419595956110321!GO:0048146;positive regulation of fibroblast proliferation;0.0421602883588834!GO:0008426;protein kinase C inhibitor activity;0.0424124142091091!GO:0031396;regulation of protein ubiquitination;0.0426647918084938!GO:0050178;phenylpyruvate tautomerase activity;0.0431381101064359!GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;0.0433122571742229!GO:0006695;cholesterol biosynthetic process;0.0433122571742229!GO:0006778;porphyrin metabolic process;0.0433122571742229!GO:0033013;tetrapyrrole metabolic process;0.0433122571742229!GO:0000793;condensed chromosome;0.0439577263142777!GO:0045944;positive regulation of transcription from RNA polymerase II promoter;0.0445869955906591!GO:0006984;ER-nuclear signaling pathway;0.0453357779634835!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0453562142687649!GO:0006767;water-soluble vitamin metabolic process;0.0458952219640231!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0461060474298095!GO:0006213;pyrimidine nucleoside metabolic process;0.0463991072100986!GO:0016614;oxidoreductase activity, acting on CH-OH group of donors;0.0469122141639148!GO:0007034;vacuolar transport;0.0470629216934662!GO:0006007;glucose catabolic process;0.0478496824921376!GO:0000288;mRNA catabolic process, deadenylation-dependent decay;0.048168181972074!GO:0006541;glutamine metabolic process;0.0481929292702256!GO:0051289;protein homotetramerization;0.0482960493538347!GO:0001832;blastocyst growth;0.0483782257529139!GO:0000159;protein phosphatase type 2A complex;0.0483890824801898!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.0483890824801898!GO:0003725;double-stranded RNA binding;0.048619353294122!GO:0030100;regulation of endocytosis;0.0486338665285193!GO:0005881;cytoplasmic microtubule;0.0486338665285193!GO:0050000;chromosome localization;0.0490392331775142!GO:0051303;establishment of chromosome localization;0.0490392331775142!GO:0030496;midbody;0.049479992492626
|sample_id=10717
|sample_id=10717
|sample_note=
|sample_note=
Line 76: Line 98:
|sample_tissue=breast
|sample_tissue=breast
|top_motifs=POU2F1..3:2.3157263219;VSX1,2:2.18099139764;ZEB1:1.63178903257;SNAI1..3:1.60392101409;POU1F1:1.57071519622;PITX1..3:1.55457296843;SP1:1.5113459458;E2F1..5:1.50679214151;NKX2-3_NKX2-5:1.41719004353;NFY{A,B,C}:1.40970113135;ADNP_IRX_SIX_ZHX:1.11073285013;TBX4,5:1.09723897721;CDC5L:1.08835308753;RBPJ:1.02583062838;FOXQ1:1.01183595704;TP53:0.949209893547;GFI1:0.896607425703;PAX8:0.846994181065;XCPE1{core}:0.845811233442;ZBTB16:0.835950950788;bHLH_family:0.767236235547;TFDP1:0.742952961847;TEAD1:0.686175008588;TEF:0.654314563926;STAT5{A,B}:0.61531656111;ZNF143:0.538993144175;ONECUT1,2:0.532614983636;FOXP1:0.514173627718;POU5F1:0.465718479713;FOX{I1,J2}:0.464386845544;TBP:0.425067334167;NKX2-1,4:0.416865715442;IKZF2:0.408776390504;TOPORS:0.386053617564;NR5A1,2:0.38249867588;OCT4_SOX2{dimer}:0.36499361327;HOX{A6,A7,B6,B7}:0.343415732441;NFIX:0.338317611457;NKX3-2:0.33562345421;FOXD3:0.333460688719;NANOG:0.306811148074;ARID5B:0.294108399338;SOX17:0.254824471035;CDX1,2,4:0.252380896571;MYOD1:0.24619245446;MYB:0.24035477462;HBP1_HMGB_SSRP1_UBTF:0.231832567888;ZNF148:0.229552650091;ZNF384:0.22844543566;PBX1:0.200621741488;AIRE:0.181132547148;HSF1,2:0.179415318037;SOX{8,9,10}:0.164804279797;LMO2:0.16413988076;FOS_FOS{B,L1}_JUN{B,D}:0.148734244801;NKX3-1:0.12868490536;PDX1:0.114868142651;NFE2L2:0.0990673353575;NFE2:0.0923311148452;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.0916430921526;FOXL1:0.0828418630958;FOXM1:0.0771900003564;PAX4:0.0533842985885;NRF1:0.030857577063;ATF4:0.025348394737;NR6A1:0.0190784778994;ELK1,4_GABP{A,B1}:0.0147896100016;EP300:0.0104560668577;FOSL2:0.00794731875238;BACH2:-0.00669451330118;MED-1{core}:-0.0265832082174;NFKB1_REL_RELA:-0.033443223296;TLX1..3_NFIC{dimer}:-0.0353455405933;UFEwm:-0.0434230310909;RFX1:-0.070902713484;IRF1,2:-0.0717763411758;IRF7:-0.0831605336315;HIC1:-0.0883001922602;KLF4:-0.0907584856138;ZIC1..3:-0.09561793513;POU6F1:-0.0966039017148;HNF4A_NR2F1,2:-0.112109624305;EGR1..3:-0.155953853824;GFI1B:-0.163546845051;BREu{core}:-0.165129000776;HOX{A5,B5}:-0.166401967364;HOXA9_MEIS1:-0.18860658614;FOXO1,3,4:-0.209240743207;DMAP1_NCOR{1,2}_SMARC:-0.210116036667;STAT1,3:-0.213114812701;NKX6-1,2:-0.222919583079;NFIL3:-0.226448297874;POU3F1..4:-0.230665378495;PAX3,7:-0.237796996337;HIF1A:-0.240285187927;CEBPA,B_DDIT3:-0.241458811901;TFAP2B:-0.246361885001;FOXN1:-0.247010037889;IKZF1:-0.250995084713;HNF1A:-0.278576960125;PRRX1,2:-0.283711704162;ESRRA:-0.285737064706;T:-0.288951370371;JUN:-0.293202240884;HES1:-0.293673884432;FOX{F1,F2,J1}:-0.294925445595;PAX1,9:-0.312774078825;HLF:-0.313216309289;ZFP161:-0.324389613975;TFAP2{A,C}:-0.340472938257;ALX1:-0.354073748165;LEF1_TCF7_TCF7L1,2:-0.357115783981;HOX{A4,D4}:-0.394315203209;MTE{core}:-0.398195122081;GLI1..3:-0.403733594906;HAND1,2:-0.428592077654;MAZ:-0.428857699187;PATZ1:-0.430510064861;CREB1:-0.430928688145;LHX3,4:-0.443308904394;ATF2:-0.443504867438;MYBL2:-0.449200228626;CUX2:-0.452458528306;CRX:-0.463354654283;PAX2:-0.465221972986;ZNF423:-0.46526402743;MEF2{A,B,C,D}:-0.472261603677;DBP:-0.487076817569;EVI1:-0.491229957983;ATF5_CREB3:-0.503144699274;GATA4:-0.518177492302;GATA6:-0.52496458555;RFX2..5_RFXANK_RFXAP:-0.525153272871;PRDM1:-0.534053636301;AHR_ARNT_ARNT2:-0.549783102626;AR:-0.565507312928;PPARG:-0.571617593143;YY1:-0.584606736502;BPTF:-0.589675087303;GCM1,2:-0.592992667425;SOX2:-0.59795917666;PAX6:-0.598871925063;PAX5:-0.599535837322;EN1,2:-0.602488472144;SPIB:-0.607832778554;REST:-0.613361698639;ALX4:-0.623232558382;ETS1,2:-0.623414368013;EBF1:-0.635451040838;GTF2I:-0.653045817818;RUNX1..3:-0.654442364802;ZBTB6:-0.658532075163;NKX2-2,8:-0.663668173901;ATF6:-0.670729633476;ESR1:-0.676317797337;FOX{D1,D2}:-0.679604267898;FOXP3:-0.681083273578;SPI1:-0.682330439741;FOXA2:-0.743262787597;SRF:-0.757657540295;ELF1,2,4:-0.764141895774;MTF1:-0.774856888069;RREB1:-0.781380195076;TFCP2:-0.791720886372;GZF1:-0.811365471419;MYFfamily:-0.831281049069;ZNF238:-0.892405010678;STAT2,4,6:-0.896418211095;SMAD1..7,9:-0.907390397424;NFE2L1:-0.912055648697;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.931897090191;HMGA1,2:-0.938568333191;XBP1:-0.952733498178;GTF2A1,2:-0.96646435258;RXR{A,B,G}:-0.98207379988;TAL1_TCF{3,4,12}:-0.988430618668;NHLH1,2:-1.03462946412;TGIF1:-1.03856622266;SREBF1,2:-1.04204673605;SOX5:-1.08009019996;NR1H4:-1.08646547417;NR3C1:-1.0996458871;NANOG{mouse}:-1.12620362442;HMX1:-1.23485054142;RORA:-1.23824793361;NFATC1..3:-1.2610264232;TLX2:-1.38939012227;SPZ1:-1.45448746321;MZF1:-1.45848529175;MAFB:-1.60273765769;TFAP4:-1.65938533637;RXRA_VDR{dimer}:-1.67077989623
|top_motifs=POU2F1..3:2.3157263219;VSX1,2:2.18099139764;ZEB1:1.63178903257;SNAI1..3:1.60392101409;POU1F1:1.57071519622;PITX1..3:1.55457296843;SP1:1.5113459458;E2F1..5:1.50679214151;NKX2-3_NKX2-5:1.41719004353;NFY{A,B,C}:1.40970113135;ADNP_IRX_SIX_ZHX:1.11073285013;TBX4,5:1.09723897721;CDC5L:1.08835308753;RBPJ:1.02583062838;FOXQ1:1.01183595704;TP53:0.949209893547;GFI1:0.896607425703;PAX8:0.846994181065;XCPE1{core}:0.845811233442;ZBTB16:0.835950950788;bHLH_family:0.767236235547;TFDP1:0.742952961847;TEAD1:0.686175008588;TEF:0.654314563926;STAT5{A,B}:0.61531656111;ZNF143:0.538993144175;ONECUT1,2:0.532614983636;FOXP1:0.514173627718;POU5F1:0.465718479713;FOX{I1,J2}:0.464386845544;TBP:0.425067334167;NKX2-1,4:0.416865715442;IKZF2:0.408776390504;TOPORS:0.386053617564;NR5A1,2:0.38249867588;OCT4_SOX2{dimer}:0.36499361327;HOX{A6,A7,B6,B7}:0.343415732441;NFIX:0.338317611457;NKX3-2:0.33562345421;FOXD3:0.333460688719;NANOG:0.306811148074;ARID5B:0.294108399338;SOX17:0.254824471035;CDX1,2,4:0.252380896571;MYOD1:0.24619245446;MYB:0.24035477462;HBP1_HMGB_SSRP1_UBTF:0.231832567888;ZNF148:0.229552650091;ZNF384:0.22844543566;PBX1:0.200621741488;AIRE:0.181132547148;HSF1,2:0.179415318037;SOX{8,9,10}:0.164804279797;LMO2:0.16413988076;FOS_FOS{B,L1}_JUN{B,D}:0.148734244801;NKX3-1:0.12868490536;PDX1:0.114868142651;NFE2L2:0.0990673353575;NFE2:0.0923311148452;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.0916430921526;FOXL1:0.0828418630958;FOXM1:0.0771900003564;PAX4:0.0533842985885;NRF1:0.030857577063;ATF4:0.025348394737;NR6A1:0.0190784778994;ELK1,4_GABP{A,B1}:0.0147896100016;EP300:0.0104560668577;FOSL2:0.00794731875238;BACH2:-0.00669451330118;MED-1{core}:-0.0265832082174;NFKB1_REL_RELA:-0.033443223296;TLX1..3_NFIC{dimer}:-0.0353455405933;UFEwm:-0.0434230310909;RFX1:-0.070902713484;IRF1,2:-0.0717763411758;IRF7:-0.0831605336315;HIC1:-0.0883001922602;KLF4:-0.0907584856138;ZIC1..3:-0.09561793513;POU6F1:-0.0966039017148;HNF4A_NR2F1,2:-0.112109624305;EGR1..3:-0.155953853824;GFI1B:-0.163546845051;BREu{core}:-0.165129000776;HOX{A5,B5}:-0.166401967364;HOXA9_MEIS1:-0.18860658614;FOXO1,3,4:-0.209240743207;DMAP1_NCOR{1,2}_SMARC:-0.210116036667;STAT1,3:-0.213114812701;NKX6-1,2:-0.222919583079;NFIL3:-0.226448297874;POU3F1..4:-0.230665378495;PAX3,7:-0.237796996337;HIF1A:-0.240285187927;CEBPA,B_DDIT3:-0.241458811901;TFAP2B:-0.246361885001;FOXN1:-0.247010037889;IKZF1:-0.250995084713;HNF1A:-0.278576960125;PRRX1,2:-0.283711704162;ESRRA:-0.285737064706;T:-0.288951370371;JUN:-0.293202240884;HES1:-0.293673884432;FOX{F1,F2,J1}:-0.294925445595;PAX1,9:-0.312774078825;HLF:-0.313216309289;ZFP161:-0.324389613975;TFAP2{A,C}:-0.340472938257;ALX1:-0.354073748165;LEF1_TCF7_TCF7L1,2:-0.357115783981;HOX{A4,D4}:-0.394315203209;MTE{core}:-0.398195122081;GLI1..3:-0.403733594906;HAND1,2:-0.428592077654;MAZ:-0.428857699187;PATZ1:-0.430510064861;CREB1:-0.430928688145;LHX3,4:-0.443308904394;ATF2:-0.443504867438;MYBL2:-0.449200228626;CUX2:-0.452458528306;CRX:-0.463354654283;PAX2:-0.465221972986;ZNF423:-0.46526402743;MEF2{A,B,C,D}:-0.472261603677;DBP:-0.487076817569;EVI1:-0.491229957983;ATF5_CREB3:-0.503144699274;GATA4:-0.518177492302;GATA6:-0.52496458555;RFX2..5_RFXANK_RFXAP:-0.525153272871;PRDM1:-0.534053636301;AHR_ARNT_ARNT2:-0.549783102626;AR:-0.565507312928;PPARG:-0.571617593143;YY1:-0.584606736502;BPTF:-0.589675087303;GCM1,2:-0.592992667425;SOX2:-0.59795917666;PAX6:-0.598871925063;PAX5:-0.599535837322;EN1,2:-0.602488472144;SPIB:-0.607832778554;REST:-0.613361698639;ALX4:-0.623232558382;ETS1,2:-0.623414368013;EBF1:-0.635451040838;GTF2I:-0.653045817818;RUNX1..3:-0.654442364802;ZBTB6:-0.658532075163;NKX2-2,8:-0.663668173901;ATF6:-0.670729633476;ESR1:-0.676317797337;FOX{D1,D2}:-0.679604267898;FOXP3:-0.681083273578;SPI1:-0.682330439741;FOXA2:-0.743262787597;SRF:-0.757657540295;ELF1,2,4:-0.764141895774;MTF1:-0.774856888069;RREB1:-0.781380195076;TFCP2:-0.791720886372;GZF1:-0.811365471419;MYFfamily:-0.831281049069;ZNF238:-0.892405010678;STAT2,4,6:-0.896418211095;SMAD1..7,9:-0.907390397424;NFE2L1:-0.912055648697;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.931897090191;HMGA1,2:-0.938568333191;XBP1:-0.952733498178;GTF2A1,2:-0.96646435258;RXR{A,B,G}:-0.98207379988;TAL1_TCF{3,4,12}:-0.988430618668;NHLH1,2:-1.03462946412;TGIF1:-1.03856622266;SREBF1,2:-1.04204673605;SOX5:-1.08009019996;NR1H4:-1.08646547417;NR3C1:-1.0996458871;NANOG{mouse}:-1.12620362442;HMX1:-1.23485054142;RORA:-1.23824793361;NFATC1..3:-1.2610264232;TLX2:-1.38939012227;SPZ1:-1.45448746321;MZF1:-1.45848529175;MAFB:-1.60273765769;TFAP4:-1.65938533637;RXRA_VDR{dimer}:-1.67077989623
|xref=
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10717-109I6;search_select_hide=table117:FF:10717-109I6
}}
}}

Latest revision as of 15:01, 3 June 2020

Name:acantholytic squamous carcinoma cell line:HCC1806
Species:Human (Homo sapiens)
Library ID:CNhs11844
Sample type:cell lines
Genomic View: UCSC
RefEX:Specific genes
CAGEd-oPOSSUM:link
ZENBU report :link
Additional information
Sample information
strainNA
tissuebreast
dev stageNA
sexfemale
age60
cell typeunclassifiable
cell lineHCC1806
companyATCC
collaborationFANTOM5 OSC CORE (contact: Al Forrest)
External link for information[{{{sample_info_link}}} {{{sample_info_link}}}]
RNA information
lot numberNA
catalog numberNA
sample typetotal RNA
extraction protocol (Details)OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0

CAGE Accession numbers
MethodSample accession id
CAGE  SAMD00005858
Library accession numbers

Library idMethodExp. accession idRun accession id
CNhs11844 CAGE DRX007796 DRR008668
Accession ID Hg19

Library idBAMCTSS
CNhs11844 DRZ000093 DRZ001478
Accession ID Hg38

Library idBAMCTSS
CNhs11844 DRZ011443 DRZ012828
Download raw sequence, BAM & CTSS
Hg19
FastaBAMCTSS
downloaddownloaddonwload
Hg38
BAMCTSS
downloaddonwload


Relative expression to median (log10)

Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.



Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data

Coexpression clusterscore
C0-CD14-Eosinophils-Neutrophils-Basophils-CD34-immature-Peripheral0
C1-testis-epididymis-embryonic-medulla-pituitary-trachea-caudate0
C10-occipital-temporal-parietal-brain-duodenum-Neurons-Neural0
C100-rhabdomyosarcoma-gastric-pineal-Wilms-cervical-mesodermal-endometrial0
C101-small-cerebellum-maxillary-colon-parietal-epididymis-merkel0
C102-neuroblastoma-testicular-pituitary-carcinosarcoma-rectum-acantholytic-iPS0
C103-CD4-CD8-Natural-Peripheral-Whole-Neutrophils-Basophils0
C104-Mast-Basophils-immature-CD14-CD34-eye-Natural0
C105-heart-skeletal-occipital-hippocampus-acute-Sebocyte-penis0.224
C106-Hep2-epitheloid-placenta-cervical-rectal-anaplastic-glassy0
C107-Neutrophils-CD14-Eosinophils-Monocytederived-Whole-Peripheral-blood0
C108-breast-hepatoblastoma-MCF7-parotid-salivary-submaxillary-prostate0
C109-Reticulocytes-non-acute-Hodgkin-Burkitt-retinoblastoma-lymphoma0.608
C11-cerebellum-medulla-pons-parietal-occipital-middle-medial0
C110-leukemia-chronic-Eosinophils-acute-Whole-CD34-Lymphatic0
C111-medulla-lung-trachea-testis-caudate-epididymis-throat0
C112-gastric-pancreas-temporal-duodenum-small-extraskeletal-adrenal0
C113-thyroid-throat-lung-lymph-small-colon-trachea0
C114-teratocarcinoma-medulloblastoma-carcinosarcoma-iPS-anaplastic-acute-neuroblastoma0
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C98-CD8-Natural-Basophils-blood-CD4-Peripheral-Whole0
C99-hairy-mycosis-submaxillary-salivary-cord-kidney-parotid0



Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data



TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample

JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs11844

Jaspar motifP-value
MA0002.20.00169
MA0003.10.378
MA0004.10.454
MA0006.10.58
MA0007.10.941
MA0009.10.374
MA0014.10.0455
MA0017.10.243
MA0018.20.368
MA0019.10.347
MA0024.17.38702e-8
MA0025.10.436
MA0027.10.607
MA0028.10.41
MA0029.10.664
MA0030.10.869
MA0031.10.785
MA0035.20.508
MA0038.17.97382e-5
MA0039.21.64592e-4
MA0040.10.149
MA0041.10.235
MA0042.10.323
MA0043.10.435
MA0046.10.36
MA0047.20.82
MA0048.10.0409
MA0050.10.131
MA0051.10.0288
MA0052.10.0138
MA0055.11.76462e-4
MA0057.10.417
MA0058.10.702
MA0059.10.763
MA0060.12.75196e-22
MA0061.10.208
MA0062.20.67
MA0065.20.819
MA0066.10.354
MA0067.10.864
MA0068.10.695
MA0069.10.776
MA0070.10.58
MA0071.10.591
MA0072.10.772
MA0073.10.807
MA0074.10.291
MA0076.10.827
MA0077.10.0815
MA0078.10.757
MA0079.20.844
MA0080.21.52078e-6
MA0081.10.00926
MA0083.10.43
MA0084.10.091
MA0087.10.292
MA0088.10.23
MA0090.10.177
MA0091.14.66345e-4
MA0092.10.316
MA0093.10.427
MA0099.20.297
MA0100.10.652
MA0101.10.77
MA0102.20.242
MA0103.17.25164e-6
MA0104.20.297
MA0105.10.0596
MA0106.10.031
MA0107.10.397
MA0108.20.0743
MA0111.10.863
MA0112.20.111
MA0113.10.113
MA0114.10.964
MA0115.10.874
MA0116.10.0383
MA0117.10.272
MA0119.10.838
MA0122.10.789
MA0124.10.744
MA0125.10.146
MA0131.10.237
MA0135.10.279
MA0136.11.52813e-4
MA0137.20.148
MA0138.20.0797
MA0139.10.86
MA0140.10.613
MA0141.10.249
MA0142.10.0179
MA0143.10.874
MA0144.10.305
MA0145.10.431
MA0146.10.218
MA0147.10.146
MA0148.10.532
MA0149.10.04
MA0150.10.696
MA0152.10.311
MA0153.10.643
MA0154.10.015
MA0155.10.31
MA0156.10.11
MA0157.10.447
MA0159.10.818
MA0160.10.443
MA0162.10.927
MA0163.10.15
MA0164.10.732
MA0258.10.0778
MA0259.10.139



FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs11844

Novel motifP-value
10.729
100.589
1000.276
1010.392
1020.638
1030.338
1040.844
1050.541
1060.813
1070.695
1080.509
1090.341
110.195
1100.647
1110.734
1120.232
1130.149
1140.0937
1150.985
1160.528
1170.501
1180.572
1190.677
120.372
1200.757
1210.969
1220.439
1230.998
1240.0685
1250.961
1260.423
1270.989
1280.358
1290.719
130.0175
1300.157
1310.0485
1320.426
1330.00139
1340.00794
1350.03
1360.0203
1370.167
1380.594
1390.00416
140.475
1400.0823
1410.026
1420.826
1430.0405
1440.206
1450.64
1460.932
1470.992
1480.0426
1490.0505
150.431
1500.389
1510.464
1520.498
1530.643
1540.818
1550.451
1560.867
1570.506
1580.297
1590.269
160.995
1600.21
1610.673
1620.309
1630.597
1640.676
1650.541
1660.434
1670.402
1680.81
1690.747
170.471
180.204
190.0377
20.52
200.0929
210.867
220.372
230.0254
240.505
250.642
260.874
270.688
280.754
290.354
30.95
300.816
310.439
320.0144
330.121
340.143
350.00605
360.226
370.476
380.854
390.57
40.745
400.0402
410.181
420.825
430.149
440.864
450.872
460.162
470.498
480.938
490.141
50.164
500.25
510.756
520.857
530.593
540.439
550.341
560.994
570.623
580.252
590.114
60.942
600.423
610.869
620.0355
630.766
640.973
650.227
665.02115e-4
670.917
680.0913
690.938
70.87
700.0407
710.691
720.339
730.701
740.0659
750.349
760.866
770.491
780.271
790.266
80.798
800.0535
810.208
820.00698
830.332
840.634
850.00615
860.0949
870.0302
880.954
890.118
90.0213
900.309
910.0208
920.0419
930.572
940.129
950.148
960.0399
970.785
980.319
990.944



de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br> library id: CNhs11844


FANTOM5 (FF) ontology

Direct parent terms


Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data

CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000066 (epithelial cell)
0000076 (squamous epithelial cell)
0000255 (eukaryotic cell)

DOID: Disease
4 (disease)
162 (cancer)
14566 (disease of cellular proliferation)
0050687 (cell type cancer)
305 (carcinoma)
1749 (squamous cell carcinoma)

FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100297 (carcinoma cell line sample)
0102024 (squamous cell carcinoma cell line sample)
0101120 (epithelial cell line sample)

Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
NA

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