FF:10764-110E8: Difference between revisions
From FANTOM5_SSTAR
(Created page with "{{f5samples
|id=FF:10764-110E8
|name=acute myeloid leukemia (FAB M5) cell line:NOMO-1, biol_rep1
|sample_id=10764
|rna_tube_id=110E8
|rna_box=110
|rna_position=E8
|samp...") |
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00004882 | ||
| | |accession_numbers=CAGE;DRX007811;DRR008683;DRZ000108;DRZ001493;DRZ011458;DRZ012843 | ||
| | |ancestors_in_anatomy_facet= | ||
| | |ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000255 | ||
| | |ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:14566,DOID:0060083,DOID:1240,DOID:8692 | ||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100737,FF:0101035,FF:0101883,FF:0100740 | |||
| | |comment= | ||
| | |created_by= | ||
|creation_date= | |||
|data_phase=2 | |||
| | |datafreeze_phase=2 | ||
| | |def= | ||
| | |expression_enrichment_score=chr13:72441315..72441454,-!p1@DACH1!2.36!436.07!DACH1;;chr16:85932760..85932775,+!p1@IRF8!2.21!161.40!IRF8;;chr7:27192185..27192209,-!p1@HOXA3!2.21!161.40!HOXA3;;chr11:47400078..47400106,-!p1@SPI1!2.18!149.90!SPI1;;chr6:135502501..135502546,+!p1@MYB!2.15!166.08!MYB;;chr7:96654133..96654150,-!p1@DLX5!2.12!130.73!DLX5;;chr7:50344289..50344323,+!p1@IKZF1!1.98!94.54!IKZF1;;chr7:27205136..27205164,-!p1@HOXA9!1.95!89.00!HOXA9;;chr2:68592406..68592424,+!p1@PLEK!1.95!87.72!PLEK;;chr3:189349162..189349207,+!p2@TP63!1.94!86.45!TP63;;chr6:135502408..135502459,+!p2@MYB!1.83!76.23!MYB;;chr12:54694758..54694805,-!p1@NFE2!1.74!65.15!NFE2;;chr18:55102628..55102646,+!p2@ONECUT2!1.73!52.80!ONECUT2;;chr18:55102598..55102623,+!p1@ONECUT2!1.68!46.84!ONECUT2;;chr19:33793430..33793447,-!p1@CEBPA!1.67!185.67!CEBPA;;chr7:27205106..27205134,-!p2@HOXA9!1.63!41.31!HOXA9;;chr2:100759037..100759058,-!p2@AFF3!1.58!36.62!AFF3;;chr1:92951607..92951661,-!p1@GFI1!1.53!32.79!GFI1;;chr16:54320617..54320643,-!p3@IRX3!1.52!41.31!IRX3;;chr13:72441074..72441172,-!p2@DACH1!1.51!31.51!DACH1;;chr10:31288398..31288455,-!p2@ZNF438!1.50!35.35!ZNF438;;chr16:54320646..54320672,-!p2@IRX3!1.49!45.14!IRX3;;chr7:115670804..115670825,-!p1@TFEC!1.48!28.96!TFEC;;chr5:88178983..88179012,-!p1@MEF2C!1.45!203.13!MEF2C;;chr19:13213662..13213686,-!p1@LYL1!1.44!38.75!LYL1;;chr7:27224842..27224872,-!p1@HOXA11!1.43!25.98!HOXA11;;chr18:22932080..22932170,-!p1@ZNF521!1.42!104.76!ZNF521;;chr7:27213893..27213954,-!p1@HOXA10!1.40!24.27!HOXA10;;chr12:54785074..54785122,-!p2@ZNF385A!1.36!33.22!ZNF385A;;chr11:47399996..47400014,-!p4@SPI1!1.35!21.29!SPI1;;chr7:27196217..27196246,-!p2@HOXA7!1.32!20.01!HOXA7;;chr12:54694807..54694832,-!p3@NFE2!1.31!19.59!NFE2;;chrX:2418949..2419024,-!p1@DHRSX,p1@ZBED1!1.31!19.59!ZBED1;;chr3:18486354..18486377,-!p2@SATB1!1.30!23.42!SATB1;;chr2:100759010..100759035,-!p1@AFF3!1.30!19.16!AFF3;;chr16:54319010..54319041,-!p8@IRX3!1.29!18.31!IRX3;;chr18:77155922..77155939,+!p1@NFATC1!1.28!48.55!NFATC1;;chr12:54785054..54785072,-!p4@ZNF385A!1.28!20.44!ZNF385A;;chr6:29648890..29648944,-!p1@ZFP57!1.28!17.89!ZFP57;;chr7:96654026..96654061,-!p2@DLX5!1.28!17.89!DLX5;;chr6:15246200..15246214,+!p2@JARID2!1.27!48.55!JARID2;;chr7:27224795..27224840,-!p2@HOXA11!1.27!17.46!HOXA11;;chr2:145277640..145277771,-!p1@ZEB2!1.25!220.16!ZEB2;;chr5:321810..321877,+!p1@AHRR!1.25!53.23!AHRR;;chr16:54320675..54320715,-!p1@IRX3!1.25!36.20!IRX3;;chr20:50159198..50159299,-!p1@NFATC2!1.23!23.42!NFATC2;;chr11:47400062..47400077,-!p2@SPI1!1.21!15.33!SPI1;;chr18:22932004..22932021,-!p2@ZNF521!1.18!14.05!ZNF521;;chr21:34442439..34442455,+!p1@OLIG1!1.17!13.63!OLIG1;;chr6:135502472..135502489,+!p3@MYB!1.17!13.63!MYB;;chr11:65554528..65554546,+!p1@OVOL1!1.14!12.78!OVOL1;;chr11:47399947..47399961,-!p3@SPI1!1.13!12.35!SPI1;;chr1:3569072..3569093,+!p1@TP73!1.13!12.35!TP73;;chr5:88179195..88179224,-!p3@MEF2C!1.11!19.16!MEF2C;;chr7:27205043..27205050,-!p5@HOXA9!1.11!11.92!HOXA9;;chr7:50343634..50343717,+!p2@IKZF1!1.11!11.92!IKZF1;;chr7:50344251..50344288,+!p3@IKZF1!1.11!11.92!IKZF1;;chr6:144385698..144385742,-!p2@PLAGL1!1.09!13.63!PLAGL1;;chrX:101975643..101975683,+!p1@BHLHB9!1.08!24.70!BHLHB9;;chr1:92949331..92949377,-!p2@GFI1!1.08!11.07!GFI1;;chr21:34442540..34442560,+!p2@OLIG1!1.08!11.07!OLIG1;;chr5:88179017..88179046,-!p2@MEF2C!1.06!42.16!MEF2C;;chr6:45390002..45390023,+!p6@RUNX2!1.04!17.46!RUNX2;;chr11:2292226..2292270,-!p1@ASCL2!1.03!9.79!ASCL2;;chr11:47400032..47400043,-!p5@SPI1!1.03!9.79!SPI1;;chr8:57123815..57123867,-!p1@PLAG1!1.00!37.47!PLAG1;;chr7:137620684..137620711,-!p4@CREB3L2!1.00!8.94!CREB3L2;;chr2:102091566..102091581,-!p1@RFX8!1.00!8.94!RFX8;;chr13:72440901..72440968,-!p4@DACH1!1.00!8.94!DACH1;;chr21:36421535..36421610,-!p2@RUNX1!0.98!31.09!RUNX1;;chr19:13213704..13213726,-!p3@LYL1!0.98!11.50!LYL1;;chr18:22931979..22931992,-!p3@ZNF521!0.98!8.52!ZNF521;;chr20:42295745..42295765,+!p1@MYBL2!0.96!135.84!MYBL2;;chr13:41593425..41593480,-!p1@ELF1!0.96!53.66!ELF1;;chr11:47400045..47400060,-!p6@SPI1!0.96!8.09!SPI1;;chr12:54778471..54778528,-!p1@ZNF385A!0.96!8.09!ZNF385A;;chr4:87857491..87857519,+!p10@AFF1!0.95!11.07!AFF1;;chr14:45722360..45722415,-!p1@MIS18BP1!0.94!124.35!MIS18BP1;;chr4:87857474..87857489,+!p7@AFF1!0.94!13.63!AFF1;;chr1:156470515..156470542,-!p2@MEF2D!0.92!40.03!MEF2D;;chr6:34204973..34204990,+!p4@HMGA1!0.91!99.65!HMGA1;;chr10:51572408..51572454,+!p3@NCOA4!0.91!43.44!NCOA4;;chr6:45390025..45390076,+!p2@RUNX2!0.91!17.89!RUNX2;;chr1:25291475..25291511,-!p2@RUNX3!0.89!6.81!RUNX3;;chr19:45579725..45579743,-!p1@ZNF296!0.87!30.24!ZNF296;;chr10:51572339..51572376,+!p4@NCOA4!0.87!14.90!NCOA4;;chr12:54694653..54694672,-!p2@NFE2!0.87!6.39!NFE2;;chr19:13213954..13214021,-!p4@LYL1!0.87!6.39!LYL1;;chr2:68592394..68592405,+!p2@PLEK!0.87!6.39!PLEK;;chr3:189348969..189349018,+!p4@TP63!0.87!6.39!TP63;;chr3:129158715..129158766,-!p2@MBD4!0.86!63.88!MBD4;;chr6:45390269..45390298,+!p5@RUNX2!0.86!10.65!RUNX2;;chr7:128577972..128578047,+!p1@IRF5!0.85!9.79!IRF5;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| ||
| | |ffid_belonging_in_development=CL:0000049,CL:0000134 | ||
| | |||
| | |||
|fonse_cell_line=FF:0101035 | |fonse_cell_line=FF:0101035 | ||
|fonse_cell_line_closure=FF:0101035 | |fonse_cell_line_closure=FF:0101035 | ||
Line 67: | Line 40: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M5%2529%2520cell%2520line%253aNOMO-1.CNhs13050.10764-110E8.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M5%2529%2520cell%2520line%253aNOMO-1.CNhs13050.10764-110E8.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M5%2529%2520cell%2520line%253aNOMO-1.CNhs13050.10764-110E8.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M5%2529%2520cell%2520line%253aNOMO-1.CNhs13050.10764-110E8.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M5%2529%2520cell%2520line%253aNOMO-1.CNhs13050.10764-110E8.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10764-110E8 | |||
|is_a=EFO:0002091;;FF:0000210;;FF:0101883 | |||
|is_obsolete= | |||
|library_id=CNhs13050 | |||
|library_id_phase_based=2:CNhs13050 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10764 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10764 | |||
|name=acute myeloid leukemia (FAB M5) cell line:NOMO-1 | |||
|namespace=FANTOM5 | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs13050,LSID1000,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0.154072694012943,0,0.107250831668294,0.26756886175468,0.0899984528711697,0.703350941177543,0,0,0,0,0,0,0,0,0,0,0.154072694012943,0,0,0.000749683664515305,0,0,0,0,0,0.169610965486623,0,0,0.467027260074951,0,0,0,0,0,0,0,0,0,0,0,0,0.00817297704693001,0.105850618773889,0,0,0,0,0,0,0,-0.0242150211128343,0,0,0,0,0,-0.0435168964137388,0,-0.0969923612426051,0,0,0.056729066799846,0,0,0,0,0,0,0,0,0,0,0,0,0,0.357465767743922,0,0,0,0.145474734559378,0,0,0,0,0,0,-0.197969472331424,0,0,0,0.396332082414707,-0.134161055689398,0.0770363470064715,0,0,0,-0.0980353512377064,0.295777235704791,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.11958035199162,0.26756886175468,0,0,0,-0.0224824114338975,0,0,0.154072694012943,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0.754677648772774,-0.0980353512377064,0,0,0.154072694012943,0,0,0,0,0,0,0,0,-0.247178875285564,0,0.67823984547819,0.010557551489471,0,0,0.019144827509756,0,0,0,0,0,0,0,0,0,-0.128119866952565,0,-0.0504125515893149,0,0,0,0,-0.0186252810838506,-0.305472230898407,0.154072694012943,0.220428768636532,-0.0683442610773682,0,0,0,0,-0.136456238456984,0,-0.120879483793741,0.468128895358412,-0.0675388940898638,-0.393653150932644,-0.04680465889238,0,0,0,-0.195059251147446,-0.0597635047789542,0,0,0.0120045791254663,0.226306439414017,0,0,-0.391044581551635,0,-0.469464191789565,-0.188428308485383,0,0.162296477813211,0,0,0,0,0,0,0,0,0,0,0,-0.0574934668214365,0.272995253174844,0,0,0,0,-0.326766753211189,0,-0.0233577243944706,0.058621735871595,-0.188695347881088,0.000577543243212685,0.277328070673286,0,0.540334768025711,-0.055167749514823,-0.141185702731371,0.453164019023021,-0.147401849371139,-0.189981719549847,0,-0.197969472331424,0.339193700926898,-0.0268632232538178,-0.0447342991558848,0,-0.873942740543183,-0.207123742058467,0,0,0,-0.497574925482749,0,0.132669325806499,0.325197401472579,0.213491668359449,-0.233521703975009,-0.0415913907141175,-0.071920513000262,0.240208644386896,-0.0395325284566706,-0.303363758883652,0,-0.173853499840703,0,0,0.00561784202737936,-0.0420118584407915,-0.0650533361188597,0.417374887649489,0,0.116006388042832,0.199224600677312,0.0770363470064715,-0.178223725364137,0.0673047946101417,0,0,-0.0833395807454172,0,0,0.259701637041822,0,0,0.185815472274551,-0.385419449017223,-0.0787828675426019,0,0.0578392482732615,0,0.0448050696229781,0,-0.159762373446997,0.0653981001438749,-0.0305052906066119,0.158036446198411,0,0.0403860448041813,-0.145812805266284,-0.119967111412475,-0.268322111378795,0.696230821960949,-0.00961316278726843,-0.440811789995645,-0.0136154871513652,-0.634867170777283,0,-0.0881268324752877,-0.0560893317760225,0.464610359981739,0.353702929206644,0,-0.241438754254007,0,-0.145747874971709,0,0.0912064884538555,0,0.442558576026653,-0.182967983729318,0.984787815716619,0.540475524233789,0,-0.293740614410227,-0.634058243761031,0,0.278464690509849,-0.0297074906600721,0.154072694012943,0.117201778420041,-0.697695966512583,0.703663590961792,-0.138989456679195,0,-0.522511296634976,0,0,-0.158868483180849,-0.0814033437514458,0.154072694012943,0.173199621410656,0.145474734559378,0.15046160757748,0.0381016205780089,0,0,-0.491627643979782,0.0366556492854007,0,-0.248462296074109,-0.0636048451378017,-0.465710629945691,-0.0992536474738128,0.051057785502664,0.439087940535648,0,0,-0.177527765965176,0.154072694012943,0.162713796400682,0,0.154072694012943,-0.249881296598824,-0.116628112990133,0,0.0770363470064715,0,0.0801588412831505,0,0,0,0,0,0,0,0.0177960282575429,-0.0872644684617676,0.154072694012943,-0.133072382505756,0,0.154072694012943,0,0,0,-0.129406115216345,0,0,-0.749606343784052,-0.0843466858172987,-0.12301741567642,0,0,0,0,-0.215723402553475,0.154229205649198,0,0.30004518533053,0,0,0,0,-0.0861409897892114,0,0,0.13378443087734,0.13378443087734,0.299735310690258,-0.0541936880498955,0,0,0,0.591554471409582,0,0,0,0,0.171704495525222,0,0,0,0,0.149208701468851,-0.0815818795468414,0,0.290213114631475,-0.0390786037105975,-1.15554764663552,0,0,-0.261347131789888,0,0,-0.249892104739266,0.0717024710472766,0,0,0,0,0,0,0,0,-0.214314512399756,0,0,0,0,0,0,0,0,0,0,0,-0.377100174987797,-0.0922240566585104,0,0,0,0,0,0,0,-0.0241060230789031,0.0562912031124461,0,0,0,0,0,0,0,0,-0.317353245650299,0,0,0,0,0,-0.0969923612426051,0,0.154072694012943,0,0,0.974793990526925,0,0,0.322621717660299,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.123319086035448,0.0899984528711697,0,0,0,0,0,0.26756886175468,0,-0.00726443645141006,0,0.431907891828162,0,0,-0.113884373708977,0,0,0,0.495187465064656,0,0.107250831668294,0.154072694012943,0,0,0,0,0,0.13378443087734,0.0770363470064715,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.367566831774333,0.0477742042093235,0,-0.0303555874280463,0,0,-0.232628352633041,0,0,0,0,0,0,-0.031340424028527,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0354449759557715,0,0,0.26756886175468,0,0,0,0,0,0,-0.0348580438050884,0,0,0,0,0,0,0,0.169610965486623,0,0,0.183391722040389,0,0,0,0,0,0,-0.210940493650238,-0.283220399823148,-0.125456368497393,0,0,0,0.161568373431626,0,0,-0.0482120461578062,0,-0.0667773874189013,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.154072694012943,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.000749683664515305,0,0,0,0,0,0,0,0,0,0,0,0,0.0770363470064715,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.178732883871961,0,0,0,0,0,0,0.290743808794052,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.470830595413191,0,0,0,-0.213086229657044,0,0,0,0,0,0,0,0,0.26756886175468,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.145420196731435,0,0,0,0,0,0,0,0,0,0,0,0,0,0.105850618773889,0,-0.0843766322300271,0,0,0,0,0,0,0,0,0,0,0,0.154072694012943,0,0,0,0.55084906368183,0.0494798073381004,0,0,0,0,0.309828657083003,0,0,0,0,0,0,0,0.0913043860701075,0,0,0,0,0,0,0,0,0,0,0,0,0,0.297238455393324,0,0,-0.107207700839143,0,0,0,0,0,0,0,0,0,0,0,0,0.09275251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| |||
|rna_box=110 | |||
|rna_catalog_number= | |||
|rna_concentration=1.8929 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=2.11 | |||
|rna_od260/280=2.09 | |||
|rna_position=E8 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=1.10E+10 | |||
|rna_weight_ug=85.1805 | |||
|sample_age=unknown | |||
|sample_category=cell lines | |||
|sample_cell_catalog=ifo50474 | |||
|sample_cell_line=NOMO-1 | |||
|sample_cell_lot= | |||
|sample_cell_type=myeloid progenitor cell | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=JAPAN HEALTH SCIENCES FOUNDATION - Health Science Research Resources Bank | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=acute myeloid leukemia (FAB M5) | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=unknown | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;3.24899169804867e-239!GO:0043227;membrane-bound organelle;6.89924221440866e-205!GO:0043231;intracellular membrane-bound organelle;1.34987679493459e-204!GO:0043226;organelle;1.54361994667191e-194!GO:0043229;intracellular organelle;6.81157581592105e-194!GO:0005737;cytoplasm;2.36907785837301e-165!GO:0044422;organelle part;9.79590883562567e-142!GO:0044446;intracellular organelle part;8.62366357207484e-140!GO:0044444;cytoplasmic part;4.1532504883578e-117!GO:0032991;macromolecular complex;5.08313387402054e-103!GO:0044237;cellular metabolic process;4.78910815238374e-100!GO:0044238;primary metabolic process;3.29964741459396e-96!GO:0005634;nucleus;2.52429046180308e-93!GO:0043170;macromolecule metabolic process;2.16063114885915e-89!GO:0030529;ribonucleoprotein complex;3.86728148065135e-86!GO:0044428;nuclear part;1.51903060681342e-84!GO:0003723;RNA binding;1.35485102772151e-78!GO:0043233;organelle lumen;8.63023774082442e-78!GO:0031974;membrane-enclosed lumen;8.63023774082442e-78!GO:0005739;mitochondrion;2.60056165429057e-68!GO:0005515;protein binding;1.29867378763208e-63!GO:0006412;translation;1.43557220427892e-54!GO:0043283;biopolymer metabolic process;1.59409476042553e-53!GO:0006396;RNA processing;4.6077504530908e-53!GO:0043234;protein complex;4.6728126919078e-52!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;4.04444987940733e-49!GO:0005840;ribosome;1.22276193972591e-48!GO:0031981;nuclear lumen;4.02540039824312e-48!GO:0044429;mitochondrial part;2.65267207788351e-46!GO:0006259;DNA metabolic process;5.01401899652915e-46!GO:0019538;protein metabolic process;1.48665208229453e-45!GO:0010467;gene expression;4.03605601627257e-45!GO:0031967;organelle envelope;1.82663265308253e-44!GO:0016071;mRNA metabolic process;1.89458366350805e-44!GO:0031975;envelope;4.44431832700491e-44!GO:0009058;biosynthetic process;7.46362243975373e-44!GO:0031090;organelle membrane;1.43317192485872e-42!GO:0044249;cellular biosynthetic process;1.94166757778665e-42!GO:0003735;structural constituent of ribosome;1.94166757778665e-42!GO:0016043;cellular component organization and biogenesis;4.31239031544293e-42!GO:0033036;macromolecule localization;9.9509632922649e-42!GO:0044260;cellular macromolecule metabolic process;5.09865860003877e-41!GO:0044267;cellular protein metabolic process;5.46553838333249e-41!GO:0009059;macromolecule biosynthetic process;8.83109108533762e-41!GO:0008380;RNA splicing;1.06681898507761e-38!GO:0015031;protein transport;1.21263291982595e-38!GO:0006397;mRNA processing;5.20317397741844e-38!GO:0033279;ribosomal subunit;1.13825965942026e-37!GO:0045184;establishment of protein localization;2.7331117711433e-37!GO:0008104;protein localization;7.00067919964189e-37!GO:0006996;organelle organization and biogenesis;9.41255676951942e-36!GO:0005829;cytosol;4.69795955908851e-35!GO:0065003;macromolecular complex assembly;2.07427004310167e-34!GO:0007049;cell cycle;3.57383072486198e-33!GO:0046907;intracellular transport;2.28923693194104e-32!GO:0005654;nucleoplasm;5.32457177757785e-32!GO:0022613;ribonucleoprotein complex biogenesis and assembly;6.22044569196537e-32!GO:0043228;non-membrane-bound organelle;1.14029173962957e-31!GO:0043232;intracellular non-membrane-bound organelle;1.14029173962957e-31!GO:0003676;nucleic acid binding;5.44354549662511e-31!GO:0000166;nucleotide binding;1.46119535701786e-30!GO:0022607;cellular component assembly;8.41836158338632e-30!GO:0005740;mitochondrial envelope;3.47288379476552e-28!GO:0019866;organelle inner membrane;3.83443655685834e-28!GO:0005681;spliceosome;1.1246156271954e-27!GO:0006886;intracellular protein transport;1.54889222061047e-27!GO:0005830;cytosolic ribosome (sensu Eukaryota);4.47356830981517e-27!GO:0005694;chromosome;1.27067304605914e-26!GO:0031966;mitochondrial membrane;1.83816159317853e-26!GO:0006974;response to DNA damage stimulus;1.97306193169179e-26!GO:0044451;nucleoplasm part;9.45373018173874e-26!GO:0005743;mitochondrial inner membrane;1.78623247214276e-25!GO:0022402;cell cycle process;4.53804354010945e-25!GO:0051649;establishment of cellular localization;8.65973013789867e-25!GO:0051641;cellular localization;4.0863990160547e-24!GO:0051276;chromosome organization and biogenesis;5.81650916422616e-24!GO:0044445;cytosolic part;8.69866085904905e-24!GO:0044427;chromosomal part;1.44397712433743e-23!GO:0006281;DNA repair;7.75056019748937e-23!GO:0031980;mitochondrial lumen;4.22561919872143e-22!GO:0005759;mitochondrial matrix;4.22561919872143e-22!GO:0000278;mitotic cell cycle;3.32407292843454e-21!GO:0006119;oxidative phosphorylation;4.12878532909406e-21!GO:0032553;ribonucleotide binding;4.58081854097627e-21!GO:0032555;purine ribonucleotide binding;4.58081854097627e-21!GO:0017076;purine nucleotide binding;7.41431990851895e-21!GO:0016070;RNA metabolic process;1.19457338720059e-20!GO:0015934;large ribosomal subunit;1.849612799327e-20!GO:0005524;ATP binding;2.54479672331067e-20!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;3.66720076960302e-20!GO:0032559;adenyl ribonucleotide binding;4.38441564403682e-20!GO:0016817;hydrolase activity, acting on acid anhydrides;4.38441564403682e-20!GO:0016462;pyrophosphatase activity;4.86801521739469e-20!GO:0030554;adenyl nucleotide binding;1.26780889331867e-19!GO:0044455;mitochondrial membrane part;1.54162155970152e-19!GO:0017111;nucleoside-triphosphatase activity;1.97380276472092e-19!GO:0006260;DNA replication;2.99378581617839e-19!GO:0022618;protein-RNA complex assembly;3.81387449166675e-19!GO:0006325;establishment and/or maintenance of chromatin architecture;4.84793060567857e-19!GO:0044265;cellular macromolecule catabolic process;7.32399037848945e-19!GO:0022403;cell cycle phase;1.40207175606788e-18!GO:0015935;small ribosomal subunit;2.56709038951023e-18!GO:0016874;ligase activity;3.1858537470667e-18!GO:0006323;DNA packaging;3.42037514663687e-18!GO:0009719;response to endogenous stimulus;3.03372354568597e-17!GO:0008135;translation factor activity, nucleic acid binding;4.18281497824899e-17!GO:0005635;nuclear envelope;6.91410908205956e-17!GO:0044248;cellular catabolic process;8.10163267147651e-17!GO:0006457;protein folding;1.35162121149909e-16!GO:0048770;pigment granule;1.5218975349591e-16!GO:0042470;melanosome;1.5218975349591e-16!GO:0005730;nucleolus;2.03692973356031e-16!GO:0000087;M phase of mitotic cell cycle;2.33023867463253e-16!GO:0012505;endomembrane system;2.56197213616264e-16!GO:0007067;mitosis;3.83310669003719e-16!GO:0005746;mitochondrial respiratory chain;5.91270093065422e-16!GO:0000279;M phase;1.04105387837078e-15!GO:0016887;ATPase activity;1.5823458517558e-15!GO:0006512;ubiquitin cycle;1.75630294256736e-15!GO:0043285;biopolymer catabolic process;2.84459597209831e-15!GO:0051301;cell division;3.1687284083566e-15!GO:0051186;cofactor metabolic process;3.42621418554533e-15!GO:0006915;apoptosis;5.02213683951016e-15!GO:0000502;proteasome complex (sensu Eukaryota);5.5640754027887e-15!GO:0012501;programmed cell death;5.77271426485426e-15!GO:0031965;nuclear membrane;5.84660823349924e-15!GO:0006605;protein targeting;7.85577166429736e-15!GO:0009057;macromolecule catabolic process;8.13126973774618e-15!GO:0006511;ubiquitin-dependent protein catabolic process;1.09198076022562e-14!GO:0019941;modification-dependent protein catabolic process;1.11461967853573e-14!GO:0043632;modification-dependent macromolecule catabolic process;1.11461967853573e-14!GO:0051603;proteolysis involved in cellular protein catabolic process;1.12249867757102e-14!GO:0008134;transcription factor binding;1.50783922176426e-14!GO:0043412;biopolymer modification;1.64003370046777e-14!GO:0042623;ATPase activity, coupled;1.72399392396882e-14!GO:0016604;nuclear body;1.97138501710666e-14!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;2.01338118321633e-14!GO:0000398;nuclear mRNA splicing, via spliceosome;2.3799493675693e-14!GO:0000375;RNA splicing, via transesterification reactions;2.3799493675693e-14!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;2.3799493675693e-14!GO:0044257;cellular protein catabolic process;2.98713905046552e-14!GO:0006913;nucleocytoplasmic transport;3.20589632096181e-14!GO:0044453;nuclear membrane part;3.21479214071709e-14!GO:0050136;NADH dehydrogenase (quinone) activity;3.65780274557668e-14!GO:0003954;NADH dehydrogenase activity;3.65780274557668e-14!GO:0008137;NADH dehydrogenase (ubiquinone) activity;3.65780274557668e-14!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);3.92218849287195e-14!GO:0005761;mitochondrial ribosome;5.87297887482515e-14!GO:0000313;organellar ribosome;5.87297887482515e-14!GO:0051169;nuclear transport;6.28752468599233e-14!GO:0016568;chromatin modification;7.6888312386193e-14!GO:0008219;cell death;1.00479236596182e-13!GO:0016265;death;1.00479236596182e-13!GO:0042254;ribosome biogenesis and assembly;1.19353047039851e-13!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);2.05994995441252e-13!GO:0050657;nucleic acid transport;2.34347998976259e-13!GO:0051236;establishment of RNA localization;2.34347998976259e-13!GO:0050658;RNA transport;2.34347998976259e-13!GO:0006403;RNA localization;2.72135844563787e-13!GO:0051082;unfolded protein binding;3.7939286969292e-13!GO:0051726;regulation of cell cycle;4.90915286018211e-13!GO:0000074;regulation of progression through cell cycle;7.51849769169031e-13!GO:0006732;coenzyme metabolic process;1.43737305066971e-12!GO:0006446;regulation of translational initiation;1.43737305066971e-12!GO:0006333;chromatin assembly or disassembly;2.30321541418392e-12!GO:0042775;organelle ATP synthesis coupled electron transport;2.45136569862861e-12!GO:0042773;ATP synthesis coupled electron transport;2.45136569862861e-12!GO:0004386;helicase activity;2.61527936818296e-12!GO:0006464;protein modification process;2.98246393164068e-12!GO:0006413;translational initiation;3.01245077770705e-12!GO:0030964;NADH dehydrogenase complex (quinone);3.01245077770705e-12!GO:0045271;respiratory chain complex I;3.01245077770705e-12!GO:0005747;mitochondrial respiratory chain complex I;3.01245077770705e-12!GO:0003743;translation initiation factor activity;3.22865657143908e-12!GO:0000785;chromatin;3.3682477451235e-12!GO:0005643;nuclear pore;7.53865295413824e-12!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;9.84308991463982e-12!GO:0044432;endoplasmic reticulum part;1.03136034512842e-11!GO:0016192;vesicle-mediated transport;1.3630102684692e-11!GO:0051028;mRNA transport;1.53488885749553e-11!GO:0043687;post-translational protein modification;1.82639889730089e-11!GO:0016607;nuclear speck;1.99821105947834e-11!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;2.26293824667847e-11!GO:0030163;protein catabolic process;4.50184427212538e-11!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;4.72803972009479e-11!GO:0006261;DNA-dependent DNA replication;4.72803972009479e-11!GO:0048193;Golgi vesicle transport;6.03987352364825e-11!GO:0006399;tRNA metabolic process;1.55036599459e-10!GO:0005783;endoplasmic reticulum;1.89869415208235e-10!GO:0065002;intracellular protein transport across a membrane;2.11202527364259e-10!GO:0008026;ATP-dependent helicase activity;2.19830015440624e-10!GO:0065004;protein-DNA complex assembly;3.50547408557578e-10!GO:0016787;hydrolase activity;4.50660667474536e-10!GO:0017038;protein import;5.03677956674247e-10!GO:0006163;purine nucleotide metabolic process;7.19213328823179e-10!GO:0009259;ribonucleotide metabolic process;8.21146443462164e-10!GO:0006164;purine nucleotide biosynthetic process;1.19964763358413e-09!GO:0006461;protein complex assembly;1.24924367503551e-09!GO:0009056;catabolic process;1.5463164254173e-09!GO:0046930;pore complex;1.57502580434011e-09!GO:0043566;structure-specific DNA binding;1.62890067270036e-09!GO:0006364;rRNA processing;1.83548373152943e-09!GO:0000775;chromosome, pericentric region;1.93251032954083e-09!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;2.42716399014199e-09!GO:0004812;aminoacyl-tRNA ligase activity;2.42716399014199e-09!GO:0016875;ligase activity, forming carbon-oxygen bonds;2.42716399014199e-09!GO:0042981;regulation of apoptosis;2.63390534504458e-09!GO:0009055;electron carrier activity;3.66761970339034e-09!GO:0009260;ribonucleotide biosynthetic process;3.93366890374011e-09!GO:0009150;purine ribonucleotide metabolic process;4.06554278574247e-09!GO:0016072;rRNA metabolic process;4.44384256690565e-09!GO:0043067;regulation of programmed cell death;4.61607764706807e-09!GO:0051246;regulation of protein metabolic process;4.93731521066738e-09!GO:0042175;nuclear envelope-endoplasmic reticulum network;5.14891362042542e-09!GO:0051188;cofactor biosynthetic process;5.20782859996113e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;5.23984841316344e-09!GO:0043038;amino acid activation;5.34690634999267e-09!GO:0006418;tRNA aminoacylation for protein translation;5.34690634999267e-09!GO:0043039;tRNA aminoacylation;5.34690634999267e-09!GO:0009152;purine ribonucleotide biosynthetic process;6.55789318025193e-09!GO:0005773;vacuole;8.93594155585385e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;9.0553703991181e-09!GO:0005789;endoplasmic reticulum membrane;9.83567378639218e-09!GO:0003697;single-stranded DNA binding;1.00502185293965e-08!GO:0005794;Golgi apparatus;1.22236946870171e-08!GO:0003712;transcription cofactor activity;1.24153999079682e-08!GO:0006793;phosphorus metabolic process;1.25992762451467e-08!GO:0006796;phosphate metabolic process;1.25992762451467e-08!GO:0009060;aerobic respiration;1.26643326023531e-08!GO:0008639;small protein conjugating enzyme activity;1.55542191974161e-08!GO:0008565;protein transporter activity;1.76838850646431e-08!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;2.43685046854114e-08!GO:0000323;lytic vacuole;2.54122402962453e-08!GO:0005764;lysosome;2.54122402962453e-08!GO:0031497;chromatin assembly;2.85943352464673e-08!GO:0030532;small nuclear ribonucleoprotein complex;2.97071021824083e-08!GO:0006334;nucleosome assembly;2.98559121938756e-08!GO:0004842;ubiquitin-protein ligase activity;3.10306054672204e-08!GO:0015986;ATP synthesis coupled proton transport;4.05093249609255e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;4.05093249609255e-08!GO:0016879;ligase activity, forming carbon-nitrogen bonds;5.42764293849759e-08!GO:0005813;centrosome;6.18324314317283e-08!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;6.3990752250812e-08!GO:0045333;cellular respiration;9.63965525333914e-08!GO:0016779;nucleotidyltransferase activity;9.84499001312078e-08!GO:0016740;transferase activity;1.10175039790236e-07!GO:0019829;cation-transporting ATPase activity;1.16780550760569e-07!GO:0005768;endosome;1.24177598135266e-07!GO:0005815;microtubule organizing center;1.33337100901658e-07!GO:0005839;proteasome core complex (sensu Eukaryota);1.40229362936131e-07!GO:0019787;small conjugating protein ligase activity;1.53741911650879e-07!GO:0015078;hydrogen ion transmembrane transporter activity;1.58853038695838e-07!GO:0006366;transcription from RNA polymerase II promoter;2.04987199977515e-07!GO:0032446;protein modification by small protein conjugation;2.40473346630872e-07!GO:0009142;nucleoside triphosphate biosynthetic process;2.41124607613721e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;2.41124607613721e-07!GO:0006916;anti-apoptosis;2.48855120961056e-07!GO:0005819;spindle;2.73535851378593e-07!GO:0009199;ribonucleoside triphosphate metabolic process;2.76030918509157e-07!GO:0009141;nucleoside triphosphate metabolic process;2.99844763950764e-07!GO:0030120;vesicle coat;3.42810850358144e-07!GO:0030662;coated vesicle membrane;3.42810850358144e-07!GO:0006099;tricarboxylic acid cycle;3.42810850358144e-07!GO:0046356;acetyl-CoA catabolic process;3.42810850358144e-07!GO:0016567;protein ubiquitination;3.46191494293792e-07!GO:0051170;nuclear import;3.46740335723428e-07!GO:0006754;ATP biosynthetic process;3.63143678316054e-07!GO:0006753;nucleoside phosphate metabolic process;3.63143678316054e-07!GO:0009108;coenzyme biosynthetic process;3.73274631252399e-07!GO:0015630;microtubule cytoskeleton;3.7688037113148e-07!GO:0008094;DNA-dependent ATPase activity;3.77702663724589e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;3.77822790993178e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;3.77822790993178e-07!GO:0043069;negative regulation of programmed cell death;3.77822790993178e-07!GO:0005793;ER-Golgi intermediate compartment;3.77822790993178e-07!GO:0048475;coated membrane;4.20463955334699e-07!GO:0030117;membrane coat;4.20463955334699e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;4.25555310679146e-07!GO:0009144;purine nucleoside triphosphate metabolic process;4.25555310679146e-07!GO:0005657;replication fork;4.38042697310286e-07!GO:0043066;negative regulation of apoptosis;4.42871549195609e-07!GO:0006084;acetyl-CoA metabolic process;5.73875644484422e-07!GO:0016310;phosphorylation;5.91135075640744e-07!GO:0046034;ATP metabolic process;6.15621876080983e-07!GO:0031202;RNA splicing factor activity, transesterification mechanism;6.23877436807763e-07!GO:0006606;protein import into nucleus;6.93830153116038e-07!GO:0004298;threonine endopeptidase activity;8.95117221661497e-07!GO:0000245;spliceosome assembly;1.17581712947465e-06!GO:0016469;proton-transporting two-sector ATPase complex;1.19279708078737e-06!GO:0051168;nuclear export;1.41791339337119e-06!GO:0009117;nucleotide metabolic process;1.47778825389774e-06!GO:0045259;proton-transporting ATP synthase complex;1.80935030465788e-06!GO:0050794;regulation of cellular process;1.87716250812472e-06!GO:0009109;coenzyme catabolic process;1.91071118451291e-06!GO:0003713;transcription coactivator activity;2.0845034709684e-06!GO:0000075;cell cycle checkpoint;2.28765538374257e-06!GO:0007005;mitochondrion organization and biogenesis;2.42850010267074e-06!GO:0051329;interphase of mitotic cell cycle;2.48907799027105e-06!GO:0006752;group transfer coenzyme metabolic process;2.73448841142964e-06!GO:0016881;acid-amino acid ligase activity;2.98230480428484e-06!GO:0016563;transcription activator activity;3.27054737338693e-06!GO:0006401;RNA catabolic process;3.27054737338693e-06!GO:0045786;negative regulation of progression through cell cycle;3.75868162152663e-06!GO:0048523;negative regulation of cellular process;3.94846660392891e-06!GO:0006950;response to stress;4.19143263174138e-06!GO:0006888;ER to Golgi vesicle-mediated transport;4.36720923049072e-06!GO:0006310;DNA recombination;5.26036017968192e-06!GO:0005762;mitochondrial large ribosomal subunit;5.40117603495308e-06!GO:0000315;organellar large ribosomal subunit;5.40117603495308e-06!GO:0006302;double-strand break repair;5.41913829050928e-06!GO:0051325;interphase;5.45064857825925e-06!GO:0051187;cofactor catabolic process;5.509758039388e-06!GO:0005667;transcription factor complex;6.66052810375958e-06!GO:0016491;oxidoreductase activity;6.81682044831038e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;7.24500471178835e-06!GO:0043623;cellular protein complex assembly;9.68643509039852e-06!GO:0003690;double-stranded DNA binding;9.8530878923652e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;1.50343321146505e-05!GO:0003724;RNA helicase activity;1.50641571429489e-05!GO:0005798;Golgi-associated vesicle;1.53441473260428e-05!GO:0007051;spindle organization and biogenesis;1.58357255320871e-05!GO:0005770;late endosome;2.12161913369021e-05!GO:0019222;regulation of metabolic process;2.60135821210411e-05!GO:0016363;nuclear matrix;2.76311698781318e-05!GO:0006613;cotranslational protein targeting to membrane;3.26924800216195e-05!GO:0051427;hormone receptor binding;4.56912917473555e-05!GO:0003684;damaged DNA binding;4.80128512158335e-05!GO:0003682;chromatin binding;5.54521081691611e-05!GO:0003729;mRNA binding;5.7817776024077e-05!GO:0031982;vesicle;5.85715007835582e-05!GO:0032508;DNA duplex unwinding;6.16324543612878e-05!GO:0032392;DNA geometric change;6.16324543612878e-05!GO:0000151;ubiquitin ligase complex;6.26726547683826e-05!GO:0008654;phospholipid biosynthetic process;6.28662418345809e-05!GO:0031988;membrane-bound vesicle;6.34425853848385e-05!GO:0042802;identical protein binding;6.50860887155908e-05!GO:0000776;kinetochore;6.90529624082982e-05!GO:0007059;chromosome segregation;7.21756253868222e-05!GO:0006091;generation of precursor metabolites and energy;7.25792648963829e-05!GO:0006268;DNA unwinding during replication;7.9058590924205e-05!GO:0048519;negative regulation of biological process;8.31143343385066e-05!GO:0035257;nuclear hormone receptor binding;9.28460941077498e-05!GO:0006414;translational elongation;9.37523432574495e-05!GO:0006417;regulation of translation;0.0001008014813961!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.00011732431785731!GO:0003899;DNA-directed RNA polymerase activity;0.000118221231337908!GO:0003678;DNA helicase activity;0.000120953886803588!GO:0043021;ribonucleoprotein binding;0.000127923246750272!GO:0006402;mRNA catabolic process;0.000132636591742839!GO:0000786;nucleosome;0.000132804924047346!GO:0016023;cytoplasmic membrane-bound vesicle;0.000133041954827046!GO:0031324;negative regulation of cellular metabolic process;0.000150798221532096!GO:0019752;carboxylic acid metabolic process;0.00016044126009058!GO:0003746;translation elongation factor activity;0.000163198944641008!GO:0006082;organic acid metabolic process;0.000164864682679389!GO:0016853;isomerase activity;0.00016909134216099!GO:0006405;RNA export from nucleus;0.000181740843806285!GO:0016741;transferase activity, transferring one-carbon groups;0.000184108568344494!GO:0031410;cytoplasmic vesicle;0.000185368639014083!GO:0005885;Arp2/3 protein complex;0.000188095433656724!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000216854121824925!GO:0051052;regulation of DNA metabolic process;0.000221030086893748!GO:0008168;methyltransferase activity;0.000237943679624181!GO:0009165;nucleotide biosynthetic process;0.000238006994167743!GO:0005788;endoplasmic reticulum lumen;0.000238137749466991!GO:0065009;regulation of a molecular function;0.000264603435854973!GO:0004518;nuclease activity;0.00026627376430159!GO:0006270;DNA replication initiation;0.000277886046142564!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000294217941403306!GO:0030658;transport vesicle membrane;0.000315968265386093!GO:0007243;protein kinase cascade;0.000326410231285373!GO:0019899;enzyme binding;0.000326410231285373!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000351213574936308!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.000360951256370305!GO:0043681;protein import into mitochondrion;0.000367077653284385!GO:0008186;RNA-dependent ATPase activity;0.000408414953198036!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.000408653705143636!GO:0050789;regulation of biological process;0.000426995143955674!GO:0031326;regulation of cellular biosynthetic process;0.00044762637020676!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000459332030565179!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.000469705437131819!GO:0000314;organellar small ribosomal subunit;0.000474612474387842!GO:0005763;mitochondrial small ribosomal subunit;0.000474612474387842!GO:0044440;endosomal part;0.000493997075179459!GO:0010008;endosome membrane;0.000493997075179459!GO:0007088;regulation of mitosis;0.000496634162264869!GO:0031323;regulation of cellular metabolic process;0.000555041494886666!GO:0015980;energy derivation by oxidation of organic compounds;0.000635202463851125!GO:0006818;hydrogen transport;0.000643992071632266!GO:0006612;protein targeting to membrane;0.000689629381545991!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000692015563540326!GO:0044431;Golgi apparatus part;0.000761381773211774!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00077515970178488!GO:0005769;early endosome;0.000777253494203071!GO:0015992;proton transport;0.000782112407146346!GO:0045454;cell redox homeostasis;0.00083509721062905!GO:0046483;heterocycle metabolic process;0.000845324154965022!GO:0016564;transcription repressor activity;0.000880972962657369!GO:0005637;nuclear inner membrane;0.000894783514520543!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000912973314392624!GO:0004527;exonuclease activity;0.000914304802367201!GO:0005525;GTP binding;0.000933288826384306!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000941486140929359!GO:0015399;primary active transmembrane transporter activity;0.000941486140929359!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000975471284630842!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000975471284630842!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000975471284630842!GO:0030660;Golgi-associated vesicle membrane;0.00102679996590033!GO:0016197;endosome transport;0.00108734493062538!GO:0004004;ATP-dependent RNA helicase activity;0.0011738814697071!GO:0005684;U2-dependent spliceosome;0.00118963181402039!GO:0006338;chromatin remodeling;0.00121735331706027!GO:0006839;mitochondrial transport;0.00123156365414368!GO:0000049;tRNA binding;0.00126916739598781!GO:0008610;lipid biosynthetic process;0.00126916739598781!GO:0000228;nuclear chromosome;0.00130277981256476!GO:0051920;peroxiredoxin activity;0.00130946297696231!GO:0006520;amino acid metabolic process;0.00133087774346624!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00141708561084097!GO:0007093;mitotic cell cycle checkpoint;0.00155823281845335!GO:0050662;coenzyme binding;0.00157568207321859!GO:0016251;general RNA polymerase II transcription factor activity;0.00160847665849954!GO:0031072;heat shock protein binding;0.00160847665849954!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.00160853997832746!GO:0044262;cellular carbohydrate metabolic process;0.00169660276242592!GO:0000082;G1/S transition of mitotic cell cycle;0.00183351000345555!GO:0032940;secretion by cell;0.00183351000345555!GO:0006626;protein targeting to mitochondrion;0.00205138865289949!GO:0051252;regulation of RNA metabolic process;0.00216339984805459!GO:0005876;spindle microtubule;0.00220523909083124!GO:0006352;transcription initiation;0.00221252588033782!GO:0003924;GTPase activity;0.00224158484058122!GO:0009892;negative regulation of metabolic process;0.00229725869154967!GO:0005774;vacuolar membrane;0.00230521046537074!GO:0006284;base-excision repair;0.00236194236990837!GO:0008033;tRNA processing;0.00238382269017082!GO:0005048;signal sequence binding;0.00241530504168384!GO:0009889;regulation of biosynthetic process;0.00243357893113352!GO:0046983;protein dimerization activity;0.00243357893113352!GO:0007052;mitotic spindle organization and biogenesis;0.00255057522577206!GO:0022890;inorganic cation transmembrane transporter activity;0.00272667005191196!GO:0030137;COPI-coated vesicle;0.00284368507882345!GO:0000922;spindle pole;0.00298147603793707!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00315390310113708!GO:0044452;nucleolar part;0.00326794437876335!GO:0003711;transcription elongation regulator activity;0.00333216039461112!GO:0047485;protein N-terminus binding;0.00333784101094228!GO:0030880;RNA polymerase complex;0.00334067897155552!GO:0030118;clathrin coat;0.00338966163463204!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00346086632744435!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00346086632744435!GO:0015631;tubulin binding;0.003531533391422!GO:0051287;NAD binding;0.00353492952202693!GO:0006383;transcription from RNA polymerase III promoter;0.00356419412065851!GO:0033116;ER-Golgi intermediate compartment membrane;0.0035884300723398!GO:0007050;cell cycle arrest;0.00363011532556678!GO:0019867;outer membrane;0.00365486668782798!GO:0030663;COPI coated vesicle membrane;0.00366841733704458!GO:0030126;COPI vesicle coat;0.00366841733704458!GO:0045045;secretory pathway;0.00367511408128238!GO:0043596;nuclear replication fork;0.0037549106669771!GO:0030384;phosphoinositide metabolic process;0.00381558214868332!GO:0042393;histone binding;0.00395050056118459!GO:0004674;protein serine/threonine kinase activity;0.00398792958686597!GO:0043492;ATPase activity, coupled to movement of substances;0.00418065036500644!GO:0031968;organelle outer membrane;0.00425196210368603!GO:0000059;protein import into nucleus, docking;0.00425713508470441!GO:0000725;recombinational repair;0.00434704088675114!GO:0000724;double-strand break repair via homologous recombination;0.00434704088675114!GO:0031570;DNA integrity checkpoint;0.00438867827213295!GO:0042770;DNA damage response, signal transduction;0.00450700115608274!GO:0032200;telomere organization and biogenesis;0.0045097826158733!GO:0000723;telomere maintenance;0.0045097826158733!GO:0043065;positive regulation of apoptosis;0.00458207761013989!GO:0048522;positive regulation of cellular process;0.00465613627308056!GO:0003725;double-stranded RNA binding;0.00466069177932842!GO:0031252;leading edge;0.00471601611356177!GO:0008632;apoptotic program;0.00481101454395919!GO:0043284;biopolymer biosynthetic process;0.00504465125143364!GO:0006595;polyamine metabolic process;0.00508077225444071!GO:0048500;signal recognition particle;0.00512502659238806!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00512688330761215!GO:0016481;negative regulation of transcription;0.00520377657019481!GO:0006650;glycerophospholipid metabolic process;0.00532746798394165!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00538656998045731!GO:0044437;vacuolar part;0.00548897664781727!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00582218305444228!GO:0016584;nucleosome positioning;0.00585391183871198!GO:0044454;nuclear chromosome part;0.00586307698111853!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00590323703445875!GO:0033367;protein localization in mast cell secretory granule;0.00590323703445875!GO:0033365;protein localization in organelle;0.00590323703445875!GO:0033371;T cell secretory granule organization and biogenesis;0.00590323703445875!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.00590323703445875!GO:0033375;protease localization in T cell secretory granule;0.00590323703445875!GO:0042629;mast cell granule;0.00590323703445875!GO:0033377;maintenance of protein localization in T cell secretory granule;0.00590323703445875!GO:0033364;mast cell secretory granule organization and biogenesis;0.00590323703445875!GO:0033380;granzyme B localization in T cell secretory granule;0.00590323703445875!GO:0033379;maintenance of protease localization in T cell secretory granule;0.00590323703445875!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.00590323703445875!GO:0033368;protease localization in mast cell secretory granule;0.00590323703445875!GO:0033366;protein localization in secretory granule;0.00590323703445875!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.00590323703445875!GO:0033374;protein localization in T cell secretory granule;0.00590323703445875!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00592823786434592!GO:0000428;DNA-directed RNA polymerase complex;0.00592823786434592!GO:0004003;ATP-dependent DNA helicase activity;0.0059603810198783!GO:0016859;cis-trans isomerase activity;0.00596639459516465!GO:0043068;positive regulation of programmed cell death;0.00602321835101697!GO:0006289;nucleotide-excision repair;0.00638579589280636!GO:0031124;mRNA 3'-end processing;0.00655844637300737!GO:0006406;mRNA export from nucleus;0.0066554803050353!GO:0031902;late endosome membrane;0.00677236060338263!GO:0007034;vacuolar transport;0.0067952589156812!GO:0048471;perinuclear region of cytoplasm;0.00681773367979043!GO:0005765;lysosomal membrane;0.00683869373114355!GO:0000910;cytokinesis;0.00692164304084795!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.00692370536609329!GO:0000792;heterochromatin;0.00695811090662808!GO:0004261;cathepsin G activity;0.00710511418010552!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00710798011836129!GO:0005741;mitochondrial outer membrane;0.00715615440521503!GO:0008139;nuclear localization sequence binding;0.00715959268529881!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.00722482879138604!GO:0046489;phosphoinositide biosynthetic process;0.00723589725053674!GO:0046822;regulation of nucleocytoplasmic transport;0.00724378206308624!GO:0000139;Golgi membrane;0.00739555473209456!GO:0007006;mitochondrial membrane organization and biogenesis;0.00743293501889172!GO:0007041;lysosomal transport;0.00749974663764737!GO:0016311;dephosphorylation;0.00756369747465075!GO:0046474;glycerophospholipid biosynthetic process;0.00756369747465075!GO:0043414;biopolymer methylation;0.00775353162044794!GO:0016126;sterol biosynthetic process;0.00797195131134218!GO:0006979;response to oxidative stress;0.00828477808250529!GO:0030176;integral to endoplasmic reticulum membrane;0.00845305202590433!GO:0046966;thyroid hormone receptor binding;0.00855136156158444!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00864986273555525!GO:0032561;guanyl ribonucleotide binding;0.00887102898466598!GO:0019001;guanyl nucleotide binding;0.00887102898466598!GO:0006611;protein export from nucleus;0.00887482411275284!GO:0030133;transport vesicle;0.00890385219644276!GO:0030134;ER to Golgi transport vesicle;0.0089050340944272!GO:0046467;membrane lipid biosynthetic process;0.00902379412751921!GO:0008312;7S RNA binding;0.00922047648223621!GO:0006376;mRNA splice site selection;0.00924102765202042!GO:0000389;nuclear mRNA 3'-splice site recognition;0.00924102765202042!GO:0005663;DNA replication factor C complex;0.0092685613775107!GO:0006891;intra-Golgi vesicle-mediated transport;0.00934618239331099!GO:0051539;4 iron, 4 sulfur cluster binding;0.0093681044771353!GO:0048037;cofactor binding;0.00948856756059847!GO:0051053;negative regulation of DNA metabolic process;0.00951710509863997!GO:0050790;regulation of catalytic activity;0.00959578622762433!GO:0016044;membrane organization and biogenesis;0.00962729318657609!GO:0005996;monosaccharide metabolic process;0.00978853724274876!GO:0009967;positive regulation of signal transduction;0.00980759102220445!GO:0006917;induction of apoptosis;0.00989260836751648!GO:0009112;nucleobase metabolic process;0.0100385931373414!GO:0009116;nucleoside metabolic process;0.0100756385008915!GO:0003887;DNA-directed DNA polymerase activity;0.0101013068016193!GO:0010468;regulation of gene expression;0.0102148424863056!GO:0030867;rough endoplasmic reticulum membrane;0.0103715490198155!GO:0016788;hydrolase activity, acting on ester bonds;0.0109167238312671!GO:0030127;COPII vesicle coat;0.0110743538745504!GO:0012507;ER to Golgi transport vesicle membrane;0.0110743538745504!GO:0005905;coated pit;0.0110999135223887!GO:0016791;phosphoric monoester hydrolase activity;0.0114667879588873!GO:0006350;transcription;0.0115365384576618!GO:0032259;methylation;0.0115516270008981!GO:0000118;histone deacetylase complex;0.0115516270008981!GO:0051540;metal cluster binding;0.0115516270008981!GO:0051536;iron-sulfur cluster binding;0.0115516270008981!GO:0035267;NuA4 histone acetyltransferase complex;0.0115806553624518!GO:0000793;condensed chromosome;0.0117785752923267!GO:0019318;hexose metabolic process;0.0118889474086378!GO:0003702;RNA polymerase II transcription factor activity;0.0120450481283693!GO:0016569;covalent chromatin modification;0.0122048079873308!GO:0008276;protein methyltransferase activity;0.0123610329954558!GO:0012502;induction of programmed cell death;0.0127858562912886!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0128511537368106!GO:0000339;RNA cap binding;0.0129029569092994!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0130618120128094!GO:0045047;protein targeting to ER;0.0130618120128094!GO:0016272;prefoldin complex;0.0130618120128094!GO:0043601;nuclear replisome;0.0132298740207911!GO:0030894;replisome;0.0132298740207911!GO:0051098;regulation of binding;0.0143403296740598!GO:0030125;clathrin vesicle coat;0.0144317649562519!GO:0030665;clathrin coated vesicle membrane;0.0144317649562519!GO:0000726;non-recombinational repair;0.0145144776222558!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0145147221528167!GO:0043488;regulation of mRNA stability;0.0146052316368245!GO:0043487;regulation of RNA stability;0.0146052316368245!GO:0007040;lysosome organization and biogenesis;0.0156979340536482!GO:0043022;ribosome binding;0.0158285562489717!GO:0016407;acetyltransferase activity;0.0158518535141283!GO:0035258;steroid hormone receptor binding;0.0158518535141283!GO:0051789;response to protein stimulus;0.0159081126907413!GO:0006986;response to unfolded protein;0.0159081126907413!GO:0006519;amino acid and derivative metabolic process;0.0159541931739636!GO:0005758;mitochondrial intermembrane space;0.0159711162413464!GO:0019206;nucleoside kinase activity;0.0161580015845532!GO:0005832;chaperonin-containing T-complex;0.0162160351812918!GO:0006497;protein amino acid lipidation;0.0164002554847189!GO:0051087;chaperone binding;0.0164784453114835!GO:0030119;AP-type membrane coat adaptor complex;0.0165006127951946!GO:0003857;3-hydroxyacyl-CoA dehydrogenase activity;0.0165230207409677!GO:0000077;DNA damage checkpoint;0.0167969216721171!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0168613563815761!GO:0000209;protein polyubiquitination;0.0171555366855648!GO:0008047;enzyme activator activity;0.0173600907258666!GO:0000123;histone acetyltransferase complex;0.0173921977261459!GO:0004540;ribonuclease activity;0.0174126557215333!GO:0019783;small conjugating protein-specific protease activity;0.0174846712237625!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.0175811903460593!GO:0006007;glucose catabolic process;0.0177849283872161!GO:0003714;transcription corepressor activity;0.0178176551341905!GO:0017166;vinculin binding;0.0180489160073295!GO:0031123;RNA 3'-end processing;0.0180631561266335!GO:0005669;transcription factor TFIID complex;0.0183310285705147!GO:0018193;peptidyl-amino acid modification;0.0183416694199146!GO:0006607;NLS-bearing substrate import into nucleus;0.0184087538228912!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0186762861549611!GO:0008234;cysteine-type peptidase activity;0.0186895506428403!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0187153764291572!GO:0043189;H4/H2A histone acetyltransferase complex;0.0187971385768871!GO:0006354;RNA elongation;0.0188572291948026!GO:0006516;glycoprotein catabolic process;0.0189426091460562!GO:0009124;nucleoside monophosphate biosynthetic process;0.0192969678201542!GO:0009123;nucleoside monophosphate metabolic process;0.0192969678201542!GO:0006275;regulation of DNA replication;0.0193083967830255!GO:0004576;oligosaccharyl transferase activity;0.0193771817264618!GO:0001726;ruffle;0.0196133713256715!GO:0008144;drug binding;0.0196558355303813!GO:0008333;endosome to lysosome transport;0.0197279980351078!GO:0007259;JAK-STAT cascade;0.0197279980351078!GO:0000781;chromosome, telomeric region;0.0197390021316325!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0197909378150455!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0199370420108605!GO:0005975;carbohydrate metabolic process;0.0200893912559093!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0200893912559093!GO:0015002;heme-copper terminal oxidase activity;0.0200893912559093!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0200893912559093!GO:0004129;cytochrome-c oxidase activity;0.0200893912559093!GO:0048487;beta-tubulin binding;0.0201951289669219!GO:0000287;magnesium ion binding;0.0202366964049402!GO:0040029;regulation of gene expression, epigenetic;0.0205167628034643!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0212009286676011!GO:0010257;NADH dehydrogenase complex assembly;0.0212009286676011!GO:0033108;mitochondrial respiratory chain complex assembly;0.0212009286676011!GO:0008022;protein C-terminus binding;0.0218342379925733!GO:0000096;sulfur amino acid metabolic process;0.0223241742239155!GO:0006892;post-Golgi vesicle-mediated transport;0.0225119156606675!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0226472463714294!GO:0005869;dynactin complex;0.0230988248370478!GO:0004843;ubiquitin-specific protease activity;0.0230988248370478!GO:0004177;aminopeptidase activity;0.0231017026122144!GO:0030521;androgen receptor signaling pathway;0.0231017026122144!GO:0004448;isocitrate dehydrogenase activity;0.0231017026122144!GO:0007033;vacuole organization and biogenesis;0.0232708048881826!GO:0030131;clathrin adaptor complex;0.0233205581899292!GO:0006779;porphyrin biosynthetic process;0.0235162972129043!GO:0033014;tetrapyrrole biosynthetic process;0.0235162972129043!GO:0000178;exosome (RNase complex);0.0237453829872457!GO:0030132;clathrin coat of coated pit;0.0240202829703439!GO:0006144;purine base metabolic process;0.0245231297285187!GO:0016408;C-acyltransferase activity;0.0247652322638754!GO:0006730;one-carbon compound metabolic process;0.0251353882776411!GO:0031970;organelle envelope lumen;0.0251606169987812!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0252680353282997!GO:0006118;electron transport;0.0256792761310806!GO:0006733;oxidoreduction coenzyme metabolic process;0.0262052860690855!GO:0004185;serine carboxypeptidase activity;0.0262052860690855!GO:0031647;regulation of protein stability;0.0279649992027619!GO:0005853;eukaryotic translation elongation factor 1 complex;0.0280103668226091!GO:0000819;sister chromatid segregation;0.0281401991074164!GO:0009119;ribonucleoside metabolic process;0.0282746857073152!GO:0016790;thiolester hydrolase activity;0.028652107494225!GO:0000070;mitotic sister chromatid segregation;0.0286881627280008!GO:0007242;intracellular signaling cascade;0.0287323608928119!GO:0005874;microtubule;0.0290368831566267!GO:0008250;oligosaccharyl transferase complex;0.0291400032298419!GO:0045947;negative regulation of translational initiation;0.029197338088388!GO:0033170;DNA-protein loading ATPase activity;0.030295520297083!GO:0003689;DNA clamp loader activity;0.030295520297083!GO:0046870;cadmium ion binding;0.0303539580132682!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0303539580132682!GO:0042158;lipoprotein biosynthetic process;0.0304957701012195!GO:0004221;ubiquitin thiolesterase activity;0.030520099851359!GO:0030374;ligand-dependent nuclear receptor transcription coactivator activity;0.0307355864859047!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.031025617210827!GO:0016570;histone modification;0.0311058268233675!GO:0005777;peroxisome;0.0311200033011773!GO:0042579;microbody;0.0311200033011773!GO:0004722;protein serine/threonine phosphatase activity;0.0311200033011773!GO:0006778;porphyrin metabolic process;0.0313598443625577!GO:0033013;tetrapyrrole metabolic process;0.0313598443625577!GO:0030130;clathrin coat of trans-Golgi network vesicle;0.0313598443625577!GO:0012510;trans-Golgi network transport vesicle membrane;0.0313598443625577!GO:0008408;3'-5' exonuclease activity;0.031415937200379!GO:0006740;NADPH regeneration;0.0316002034772995!GO:0006098;pentose-phosphate shunt;0.0316002034772995!GO:0051092;activation of NF-kappaB transcription factor;0.0316559686860087!GO:0007017;microtubule-based process;0.0325423829626273!GO:0006378;mRNA polyadenylation;0.0325510430646404!GO:0051223;regulation of protein transport;0.032906450102747!GO:0006695;cholesterol biosynthetic process;0.0329394607045504!GO:0044438;microbody part;0.0334363881795878!GO:0044439;peroxisomal part;0.0334363881795878!GO:0005784;translocon complex;0.0345027838960879!GO:0046426;negative regulation of JAK-STAT cascade;0.0345052345106407!GO:0019377;glycolipid catabolic process;0.034594537515002!GO:0006596;polyamine biosynthetic process;0.0347491638824855!GO:0006509;membrane protein ectodomain proteolysis;0.0347491638824855!GO:0033619;membrane protein proteolysis;0.0347491638824855!GO:0008180;signalosome;0.0350370544946774!GO:0006506;GPI anchor biosynthetic process;0.0352852045275938!GO:0019843;rRNA binding;0.0352852045275938!GO:0016279;protein-lysine N-methyltransferase activity;0.035717635450281!GO:0018024;histone-lysine N-methyltransferase activity;0.035717635450281!GO:0016278;lysine N-methyltransferase activity;0.035717635450281!GO:0046128;purine ribonucleoside metabolic process;0.035717635450281!GO:0042278;purine nucleoside metabolic process;0.035717635450281!GO:0009161;ribonucleoside monophosphate metabolic process;0.035792612024304!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.035792612024304!GO:0044450;microtubule organizing center part;0.037676211083424!GO:0030518;steroid hormone receptor signaling pathway;0.0377043367644182!GO:0048518;positive regulation of biological process;0.0378593448158838!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0378974185272218!GO:0045792;negative regulation of cell size;0.0379326535892867!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.0380046289990674!GO:0009615;response to virus;0.038071726679415!GO:0008017;microtubule binding;0.0385340144184213!GO:0006672;ceramide metabolic process;0.0392823432088904!GO:0017134;fibroblast growth factor binding;0.0393388901498524!GO:0008287;protein serine/threonine phosphatase complex;0.0393388901498524!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0393388901498524!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0395580176603076!GO:0006807;nitrogen compound metabolic process;0.0395580176603076!GO:0009066;aspartate family amino acid metabolic process;0.0407072224473314!GO:0004096;catalase activity;0.040830722821673!GO:0006769;nicotinamide metabolic process;0.0412750654529516!GO:0030224;monocyte differentiation;0.0415462276125859!GO:0004563;beta-N-acetylhexosaminidase activity;0.0415521671782767!GO:0004523;ribonuclease H activity;0.0418594464340529!GO:0008156;negative regulation of DNA replication;0.0426032319918651!GO:0000152;nuclear ubiquitin ligase complex;0.0427012363147414!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0428172094243958!GO:0007021;tubulin folding;0.0429050829701173!GO:0006213;pyrimidine nucleoside metabolic process;0.0433864177413505!GO:0005652;nuclear lamina;0.043680080401817!GO:0006505;GPI anchor metabolic process;0.043680080401817!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.0439223630263057!GO:0001832;blastocyst growth;0.0445792131185857!GO:0009308;amine metabolic process;0.0452067343735808!GO:0030911;TPR domain binding;0.0452067343735808!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.0452067343735808!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.0452067343735808!GO:0009126;purine nucleoside monophosphate metabolic process;0.0452067343735808!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.0452067343735808!GO:0006767;water-soluble vitamin metabolic process;0.0453615765195899!GO:0046554;malate dehydrogenase (NADP+) activity;0.0455109242518253!GO:0031903;microbody membrane;0.0463594730495308!GO:0005778;peroxisomal membrane;0.0463594730495308!GO:0030308;negative regulation of cell growth;0.0463905944534078!GO:0046365;monosaccharide catabolic process;0.046641896203014!GO:0030508;thiol-disulfide exchange intermediate activity;0.0470837668299907!GO:0007010;cytoskeleton organization and biogenesis;0.0473069015887417!GO:0051452;cellular pH reduction;0.048388714847147!GO:0051453;regulation of cellular pH;0.048388714847147!GO:0045851;pH reduction;0.048388714847147!GO:0003893;epsilon DNA polymerase activity;0.0489263028824314!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0489263028824314 | |||
|sample_id=10764 | |||
|sample_note= | |||
|sample_sex=female | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=RXR{A,B,G}_{NR1H2,PPAR}dimers:1.88410613977;MYB:1.8024348309;E2F1..5:1.50662764671;FOXA2:1.37659039163;MTF1:1.32768983287;POU5F1:1.31348507274;HOX{A6,A7,B6,B7}:1.26094247399;NANOG:1.2151302696;POU2F1..3:1.14858106798;YY1:0.952615884926;NFY{A,B,C}:0.931512065545;BREu{core}:0.832220757348;SPIB:0.829873434172;TOPORS:0.761874632397;SPI1:0.742520648454;FOXP1:0.720436852554;OCT4_SOX2{dimer}:0.717655386318;PITX1..3:0.636551990338;DMAP1_NCOR{1,2}_SMARC:0.630889218223;ELK1,4_GABP{A,B1}:0.614593796292;ETS1,2:0.556008898383;CRX:0.53922716774;ELF1,2,4:0.537423027995;IKZF2:0.518356580762;TFDP1:0.507628327996;HAND1,2:0.480661566526;CUX2:0.455717122646;NFIL3:0.451719673798;NKX3-1:0.432449488276;EN1,2:0.422324446744;VSX1,2:0.407720848006;FOXN1:0.394887305052;POU1F1:0.336802856311;GATA6:0.331911879785;SREBF1,2:0.289043537015;NKX2-3_NKX2-5:0.283880566199;PRRX1,2:0.274414975881;PAX3,7:0.253869626846;CEBPA,B_DDIT3:0.252994027499;FOXP3:0.241265098361;ZNF143:0.236980609822;MYOD1:0.195849742402;NR5A1,2:0.193038181551;DBP:0.19164071582;RUNX1..3:0.191260248455;HLF:0.139402134252;HNF4A_NR2F1,2:0.136641464994;RXRA_VDR{dimer}:0.133385388347;FOXQ1:0.132512886126;PAX2:0.0910226778088;HOX{A4,D4}:0.0840197023242;NRF1:0.0621820849005;NKX2-1,4:0.061160903784;CREB1:0.0592565777416;CDX1,2,4:0.0337514586589;AHR_ARNT_ARNT2:0.017928884621;GFI1:0.015414205315;TBP:-0.0277668878305;TLX2:-0.0396683067568;ZBTB16:-0.051121728477;RORA:-0.0517577272538;TGIF1:-0.115159376232;HOX{A5,B5}:-0.120912407735;POU3F1..4:-0.125112588206;PPARG:-0.140868286304;NKX2-2,8:-0.142248715556;ATF4:-0.148826338249;PBX1:-0.152246625091;AIRE:-0.159797357147;EP300:-0.163870548624;NR6A1:-0.16513433013;SOX17:-0.169045275773;POU6F1:-0.17647991341;PRDM1:-0.177989121139;STAT1,3:-0.186143611236;ESRRA:-0.201866605173;SP1:-0.202178092159;PAX6:-0.205076706925;AR:-0.210459911915;PAX4:-0.222824058947;IRF1,2:-0.229238401135;ZNF423:-0.247131997547;SOX{8,9,10}:-0.249047178027;NFE2:-0.254625136129;HMGA1,2:-0.255624751778;ALX1:-0.26345092961;REST:-0.266734034682;ATF5_CREB3:-0.277571139459;HBP1_HMGB_SSRP1_UBTF:-0.278878640752;TEF:-0.283747124908;HNF1A:-0.294764064336;HOXA9_MEIS1:-0.299275919346;NFKB1_REL_RELA:-0.309894505811;XCPE1{core}:-0.323366569002;IRF7:-0.330368209452;MTE{core}:-0.333970856793;ZNF148:-0.362753721308;bHLH_family:-0.371294772115;MYFfamily:-0.383496367227;SNAI1..3:-0.389586271643;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.397771021078;NANOG{mouse}:-0.398551042732;ZEB1:-0.399401089074;FOS_FOS{B,L1}_JUN{B,D}:-0.414845043797;NKX3-2:-0.420823622471;PAX8:-0.423002062468;NHLH1,2:-0.448176634863;RFX2..5_RFXANK_RFXAP:-0.448564558022;ESR1:-0.460442774449;KLF4:-0.469224125693;GCM1,2:-0.48545754911;MZF1:-0.493330140135;LMO2:-0.507882917549;GATA4:-0.521252187033;MED-1{core}:-0.523878056957;TP53:-0.54735973237;FOXO1,3,4:-0.587577155798;MEF2{A,B,C,D}:-0.594224536986;FOSL2:-0.59483507782;BACH2:-0.599084422973;PDX1:-0.605810290407;FOX{F1,F2,J1}:-0.627431350808;PAX5:-0.630195291911;ARID5B:-0.637793736987;GFI1B:-0.643587927633;SOX5:-0.648875905372;RXR{A,B,G}:-0.655156856848;HSF1,2:-0.678591494507;MYBL2:-0.679124952438;HIC1:-0.683258769117;NFIX:-0.704325000144;XBP1:-0.706912645613;T:-0.714343260014;ZNF238:-0.719625754853;ZFP161:-0.722487919006;GTF2A1,2:-0.741666321613;HIF1A:-0.743465423929;STAT5{A,B}:-0.745920039277;GZF1:-0.755580747454;PAX1,9:-0.761898408988;EGR1..3:-0.764036906321;NFE2L2:-0.801646271507;ATF2:-0.803502110968;CDC5L:-0.809331963102;NKX6-1,2:-0.819468277743;ONECUT1,2:-0.827393307896;UFEwm:-0.830308909577;HES1:-0.830330250588;TFAP4:-0.842950100989;TFAP2{A,C}:-0.854851322455;RBPJ:-0.85488501153;ADNP_IRX_SIX_ZHX:-0.873039434727;MAFB:-0.875294732471;GTF2I:-0.888762691652;LEF1_TCF7_TCF7L1,2:-0.900207251025;NFE2L1:-0.911101444801;TFAP2B:-0.915757255406;ZNF384:-0.920099401146;FOXL1:-0.921648634383;BPTF:-0.930556369511;NR1H4:-0.944279266894;HMX1:-0.952791396134;SRF:-0.974045564037;RFX1:-1.02267964836;ZIC1..3:-1.02473799043;SMAD1..7,9:-1.02917880472;LHX3,4:-1.05166199408;TAL1_TCF{3,4,12}:-1.10292297993;EBF1:-1.12567613803;RREB1:-1.13282688099;EVI1:-1.14975124764;IKZF1:-1.15889813681;PATZ1:-1.18359768448;FOX{I1,J2}:-1.18903488846;STAT2,4,6:-1.19076553679;TFCP2:-1.19233849854;FOXD3:-1.20196433549;TLX1..3_NFIC{dimer}:-1.21262617753;SOX2:-1.21639302551;FOXM1:-1.27199353689;TEAD1:-1.29194953288;SPZ1:-1.29961538598;FOX{D1,D2}:-1.30209583367;JUN:-1.30430826595;NFATC1..3:-1.33454378043;MAZ:-1.37100109737;GLI1..3:-1.37132327652;ATF6:-1.45665287296;ALX4:-1.52435450717;TBX4,5:-1.5424170329;ZBTB6:-1.69612298263;NR3C1:-2.03273776278 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10764-110E8;search_select_hide=table117:FF:10764-110E8 | |||
}} | }} |
Latest revision as of 15:03, 3 June 2020
Name: | acute myeloid leukemia (FAB M5) cell line:NOMO-1 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13050 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13050
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13050
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.272 |
10 | 10 | 0.0191 |
100 | 100 | 0.327 |
101 | 101 | 0.287 |
102 | 102 | 0.377 |
103 | 103 | 0.874 |
104 | 104 | 0.777 |
105 | 105 | 0.574 |
106 | 106 | 0.924 |
107 | 107 | 0.277 |
108 | 108 | 0.539 |
109 | 109 | 0.0701 |
11 | 11 | 0.331 |
110 | 110 | 0.754 |
111 | 111 | 0.35 |
112 | 112 | 0.163 |
113 | 113 | 0.684 |
114 | 114 | 0.954 |
115 | 115 | 0.164 |
116 | 116 | 0.879 |
117 | 117 | 0.101 |
118 | 118 | 0.222 |
119 | 119 | 0.762 |
12 | 12 | 0.489 |
120 | 120 | 0.559 |
121 | 121 | 0.852 |
122 | 122 | 0.369 |
123 | 123 | 0.0156 |
124 | 124 | 0.512 |
125 | 125 | 0.765 |
126 | 126 | 0.672 |
127 | 127 | 0.117 |
128 | 128 | 0.691 |
129 | 129 | 0.531 |
13 | 13 | 6.98667e-4 |
130 | 130 | 0.927 |
131 | 131 | 0.0304 |
132 | 132 | 0.559 |
133 | 133 | 0.673 |
134 | 134 | 0.467 |
135 | 135 | 0.668 |
136 | 136 | 0.128 |
137 | 137 | 0.264 |
138 | 138 | 0.413 |
139 | 139 | 0.633 |
14 | 14 | 0.772 |
140 | 140 | 0.41 |
141 | 141 | 0.401 |
142 | 142 | 0.922 |
143 | 143 | 0.864 |
144 | 144 | 0.808 |
145 | 145 | 0.356 |
146 | 146 | 0.623 |
147 | 147 | 0.363 |
148 | 148 | 0.558 |
149 | 149 | 0.304 |
15 | 15 | 0.707 |
150 | 150 | 0.784 |
151 | 151 | 0.905 |
152 | 152 | 0.439 |
153 | 153 | 0.901 |
154 | 154 | 0.482 |
155 | 155 | 0.0587 |
156 | 156 | 0.933 |
157 | 157 | 0.243 |
158 | 158 | 0.628 |
159 | 159 | 0.884 |
16 | 16 | 0.458 |
160 | 160 | 0.591 |
161 | 161 | 0.121 |
162 | 162 | 0.907 |
163 | 163 | 0.532 |
164 | 164 | 0.587 |
165 | 165 | 0.399 |
166 | 166 | 0.266 |
167 | 167 | 0.123 |
168 | 168 | 0.424 |
169 | 169 | 0.257 |
17 | 17 | 0.817 |
18 | 18 | 0.619 |
19 | 19 | 0.975 |
2 | 2 | 0.0981 |
20 | 20 | 0.243 |
21 | 21 | 0.161 |
22 | 22 | 0.482 |
23 | 23 | 0.0194 |
24 | 24 | 0.355 |
25 | 25 | 0.207 |
26 | 26 | 0.364 |
27 | 27 | 1 |
28 | 28 | 0.796 |
29 | 29 | 0.503 |
3 | 3 | 0.21 |
30 | 30 | 0.0398 |
31 | 31 | 0.0991 |
32 | 32 | 0.0472 |
33 | 33 | 0.491 |
34 | 34 | 0.766 |
35 | 35 | 0.803 |
36 | 36 | 0.102 |
37 | 37 | 0.702 |
38 | 38 | 0.386 |
39 | 39 | 0.341 |
4 | 4 | 0.0363 |
40 | 40 | 0.0597 |
41 | 41 | 0.879 |
42 | 42 | 0.682 |
43 | 43 | 0.724 |
44 | 44 | 0.906 |
45 | 45 | 0.234 |
46 | 46 | 0.912 |
47 | 47 | 0.295 |
48 | 48 | 0.385 |
49 | 49 | 0.347 |
5 | 5 | 0.438 |
50 | 50 | 0.781 |
51 | 51 | 0.775 |
52 | 52 | 0.59 |
53 | 53 | 0.235 |
54 | 54 | 0.48 |
55 | 55 | 0.867 |
56 | 56 | 0.642 |
57 | 57 | 0.419 |
58 | 58 | 0.0575 |
59 | 59 | 0.505 |
6 | 6 | 0.982 |
60 | 60 | 0.639 |
61 | 61 | 0.122 |
62 | 62 | 0.198 |
63 | 63 | 0.387 |
64 | 64 | 0.804 |
65 | 65 | 0.291 |
66 | 66 | 0.00398 |
67 | 67 | 0.822 |
68 | 68 | 0.605 |
69 | 69 | 0.863 |
7 | 7 | 0.0688 |
70 | 70 | 0.473 |
71 | 71 | 0.051 |
72 | 72 | 0.227 |
73 | 73 | 0.463 |
74 | 74 | 0.892 |
75 | 75 | 0.0811 |
76 | 76 | 0.278 |
77 | 77 | 0.0579 |
78 | 78 | 0.0591 |
79 | 79 | 0.18 |
8 | 8 | 0.579 |
80 | 80 | 0.608 |
81 | 81 | 0.489 |
82 | 82 | 0.132 |
83 | 83 | 0.234 |
84 | 84 | 0.513 |
85 | 85 | 0.149 |
86 | 86 | 0.665 |
87 | 87 | 0.0286 |
88 | 88 | 0.425 |
89 | 89 | 0.122 |
9 | 9 | 0.773 |
90 | 90 | 0.384 |
91 | 91 | 0.316 |
92 | 92 | 0.34 |
93 | 93 | 0.89 |
94 | 94 | 0.661 |
95 | 95 | 0.0581 |
96 | 96 | 0.91 |
97 | 97 | 0.57 |
98 | 98 | 0.363 |
99 | 99 | 0.0288 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13050
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0101883 acute myeloid leukemia cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
1240 (leukemia)
8692 (myeloid leukemia)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100737 (leukemia cell line sample)
0101035 (hematopoietic cell line sample)
0101883 (acute myeloid leukemia cell line sample)
0100740 (myeloid leukemia cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)