FF:10766-110F1: Difference between revisions
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{{f5samples | {{f5samples | ||
|ancestors_in_anatomy_facet= | |DRA_sample_Accession=CAGE@SAMD00004724 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |accession_numbers=CAGE;DRX007854;DRR008726;DRZ000151;DRZ001536;DRZ011501;DRZ012886 | ||
| | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000255 | |||
|ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:14566,DOID:0060083,DOID:1240,DOID:8692,DOID:8552 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100737,FF:0101035,FF:0100740 | |||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
|expression_enrichment_score | |||
|fonse_cell_line=FF:0101035 | |fonse_cell_line=FF:0101035 | ||
|fonse_cell_line_closure=FF:0101035 | |fonse_cell_line_closure=FF:0101035 | ||
Line 35: | Line 41: | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/chronic%2520myelogenous%2520leukemia%2520%2528CML%2529%2520cell%2520line%253aMEG-A2.CNhs11865.10766-110F1.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/chronic%2520myelogenous%2520leukemia%2520%2528CML%2529%2520cell%2520line%253aMEG-A2.CNhs11865.10766-110F1.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/chronic%2520myelogenous%2520leukemia%2520%2528CML%2529%2520cell%2520line%253aMEG-A2.CNhs11865.10766-110F1.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/chronic%2520myelogenous%2520leukemia%2520%2528CML%2529%2520cell%2520line%253aMEG-A2.CNhs11865.10766-110F1.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/chronic%2520myelogenous%2520leukemia%2520%2528CML%2529%2520cell%2520line%253aMEG-A2.CNhs11865.10766-110F1.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10766-110F1 | |id=FF:10766-110F1 | ||
|is_a=DOID:8552;;EFO:0002091;;FF: | |is_a=DOID:8552;;EFO:0002091;;FF:0000210;;FF:0100740 | ||
|is_obsolete= | |||
|library_id=CNhs11865 | |||
|library_id_phase_based=2:CNhs11865 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10766 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10766 | |||
|name=chronic myelogenous leukemia (CML) cell line:MEG-A2 | |name=chronic myelogenous leukemia (CML) cell line:MEG-A2 | ||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
Line 42: | Line 60: | ||
|profile_cagescan=,,, | |profile_cagescan=,,, | ||
|profile_hcage=CNhs11865,LSID830,release010,COMPLETED | |profile_hcage=CNhs11865,LSID830,release010,COMPLETED | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq=,,, | |profile_srnaseq=,,, | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,0.0153778543056604,0.124642239360321,-0.012131099988893,0.0781787692395805,0,0,0,0,0,0,0,0,0,0,0.0667773874189013,0,0,0.298206839558435,0,0,0,0,0,0.378372248853635,0,0,0.0427392946131842,0,0,0,0,0,0,0,0,0,0,0,0,0.0377496728446478,0.0667773874189013,0,0,0,0,0,0,0,-0.0242150211128343,0,0,0,0,0,-0.000367722402387305,0,0.270306418378716,0,0,0.0272986121472241,0,0,0,0,0,0,0,0,0.0667773874189013,0,0.0667773874189013,0,0,0,0,0,0,0,0.0333886937094506,0,0.0895548946028352,0,0,0,0.060247795395435,0.0333886937094506,0,0,-0.055173485407648,0.177268423163745,0,0,0.0333886937094506,0,0.0266068881226147,0.00559862131281255,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0629849002130105,0,0,0,0,-0.130111131113456,0,0,0.0667773874189013,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0.0667773874189013,0.0266068881226147,0,0,0.124642239360321,0.0667773874189013,0.0667773874189013,0.0667773874189013,0,0.175695884392047,0,0,0,-0.180401487866663,0.171978590095998,-0.349443979391687,-0.0188729031631508,0,0.124642239360321,-0.339431144713547,0,0,0,0,0.124642239360321,0,0.0667773874189013,0.0667773874189013,0,-0.0034776275922436,0,-0.0504125515893149,0,0,0,0,-0.0186252810838506,-0.305472230898407,0,-0.140869367440059,-0.0683442610773682,0,0,0,0,0.0113288290782979,0,0.00376275556658046,0.0929757160686292,-0.154834200683905,-0.404913363740859,-0.04680465889238,0,0,0,-0.339778999628162,-0.542048768271195,0,0,-0.121779851751874,0.167660631310028,0,0,-0.391044581551635,0.0667773874189013,0.0518152924592293,-0.127631414476779,0,0.0593615669661583,0,0,0,0,0.0333886937094506,0,0,0,0,0,0,0.155120087811489,-0.105614339870455,0,0,0,0,-0.361446570125242,0,0,-0.373286155956567,-0.0482577196763466,-0.0997707187576958,-0.135139172014795,0,0.064909052611408,0.099413865710589,-0.274043753265689,-0.055173485407648,-0.147401849371139,-0.189981719549847,0,0.139818994994082,0.0256363804345082,0.0954410278792693,0.060247795395435,0.0375202094942032,-1.2314085082871,0.0871444124702943,0,0,0,-0.698366399818528,0,0.0667773874189013,-0.314418830084727,-0.185592493813454,-0.176669716704657,-0.141114922585033,0.00796124115306285,-0.000748131617802628,-0.0395325284566706,-0.122283212149975,0,-0.359251205223539,0,0.124642239360321,-0.00490679419604145,-0.116657859351566,-0.286121704282792,0.824986426637867,0,-0.00764731668928786,0.47487611066474,0,-0.56869935787123,0.104943193336772,0.0667773874189013,0.0667773874189013,-0.056729188522652,0,0,0,0,0,-0.0344700268244846,-0.414849903669845,0.0675812370525023,0,0.0182785276428776,-0.0139491787263393,-0.129709459979276,0,-0.20803552258625,-0.0775285222504844,0.0385584975125097,0.249024697356229,0,0.0993807876640314,-0.0443724565892069,-0.164990696339003,0.229894606967169,0.00833056060707614,0.206330105007119,0.318572304869617,-0.134912059294404,-0.788939864790226,-0.0497038155871057,-0.0213494450563864,0,-0.816767363099479,-0.612720744202623,0,0.283534088783998,0.125019859785456,-0.125673594870794,0,0.00753950195577091,0,0.304560766282591,-0.173134971851919,0.51389800149627,0.139610924864299,0,-0.0555336694600507,-0.788130937773974,0,-0.086913560864674,-0.0642376094305031,0,0.150069715273408,-0.697695966512583,-0.178261734155139,-0.0766683369990341,0,-0.246859786647548,0,0,0.242770827860686,0.0649607608436583,0,-0.0957598482830296,-0.157673064306533,0.172946096816404,0.00867116592538704,0.124642239360321,0,-0.645700337992725,0,0,-0.0838800214692703,-0.109713177568614,-0.252484544337312,-0.0776304570947092,-0.0380505456788865,-0.108622809454255,0,0,-0.177527765965176,0.262702198217197,0.112641491682335,0,0,-0.0823046762255134,-0.116628112990133,0,0,0,0.098211956136003,0,0,0,0,0.0446877523908511,0,0,0.262270317821452,-0.230191090856127,0,0,0,0,0,0,0,0,0,0,-0.579162572371733,0.019416887778855,-0.0562400282575189,0,0,0,0,0.0847133960545724,0.0181376947137905,0,-0.00722046713731062,0,0,0.0667773874189013,0.0667773874189013,0.0895548946028352,0,0,0,0.0333886937094506,0.00904693036523734,-0.231734092974292,0,0,0,-0.0555801447932762,0,0,0,0,-0.163002443902274,0,0,-0.0685218431101201,0,-0.209796990009481,0.253571361199779,0,0.213043908547709,-0.29997810038864,-0.858090490741599,0,0,0.612685407839998,0,0.0333886937094506,0.210090374818507,0,0.0667773874189013,0,0,0,0,0,0,0,-0.214314512399756,0,0,0,0,0,0,0,0,0,0,0,-0.118126971848126,-0.0254466692396091,0,0,0,0,0,0,0,-0.0241060230789031,0.225385703949932,0.0333886937094506,0,0,0,0,0.0667773874189013,0,0,0.0283644631612888,0,0,0.175695884392047,0,0,0.270306418378716,0,0.175695884392047,0,0,-0.065016718329353,0,0,0.147864977072337,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.123319086035448,-0.298470325129417,0,0,0,0,0,0.124642239360321,0,-0.012131099988893,0,0.221374256808514,0,0,0.14881782450822,0,0,0,0.07089949960289,0,0.0153778543056604,0,0,0,0.0623211196801605,0,0,0.0623211196801605,0.0957098133896112,0,0,0,0,0,0,0,0,0,0,0,0,0,0.142137396438457,0,-0.220430128554008,0.00864200401928361,0,0,-0.199239658923591,0,0,0,0,0,0,0.0309806956516335,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0085160625081406,0.0333886937094506,0,0,0,0,0,0,0,0,0.0284162680703179,0,0,0,0,0,0,0,0.378372248853635,0,0,0.00367700358908505,0,0,0,0,0,0,-0.15662574154811,-0.0996133068096735,-0.106650254620368,0,0,0,0.0334623697135683,0,0,-0.0245505984044617,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0333886937094506,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.298206839558435,0,0,0,0,0,0,0,0,0,0,0,0,0.0333886937094506,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0667773874189013,0,0,0,0,0,0,0.116157698600767,0.0667773874189013,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0333886937094506,0,0,0,0,0.0667773874189013,0.0956774161234081,0,0,0,0.238443620249819,0,0,0,0,0,0,0,0,0.0667773874189013,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0667773874189013,0,0,0,-0.104992068342348,0,0,0,0,0,0,0,0,0,0,0,0,0,0.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| |||
|rna_box=110 | |rna_box=110 | ||
|rna_catalog_number= | |rna_catalog_number= | ||
Line 57: | Line 78: | ||
|rna_weight_ug=31.9842 | |rna_weight_ug=31.9842 | ||
|sample_age=20 | |sample_age=20 | ||
|sample_category=cell lines | |||
|sample_cell_catalog=ifo50478 | |sample_cell_catalog=ifo50478 | ||
|sample_cell_line=MEG-A2 | |sample_cell_line=MEG-A2 | ||
Line 69: | Line 91: | ||
|sample_ethnicity=unknown | |sample_ethnicity=unknown | ||
|sample_experimental_condition= | |sample_experimental_condition= | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;2.72953891144559e-284!GO:0043227;membrane-bound organelle;3.36780856579285e-240!GO:0043231;intracellular membrane-bound organelle;1.73767795876189e-239!GO:0043226;organelle;2.44965966419513e-229!GO:0043229;intracellular organelle;2.91587823439628e-228!GO:0005737;cytoplasm;2.01771939721719e-178!GO:0044422;organelle part;1.79401303042191e-157!GO:0044446;intracellular organelle part;1.77780359467136e-155!GO:0044237;cellular metabolic process;3.37274050855418e-128!GO:0044444;cytoplasmic part;3.45257715028467e-127!GO:0044238;primary metabolic process;4.91223940635436e-122!GO:0005634;nucleus;5.32312129081456e-117!GO:0043170;macromolecule metabolic process;2.31697973925447e-112!GO:0032991;macromolecular complex;1.05316502891168e-110!GO:0030529;ribonucleoprotein complex;2.38462887172331e-95!GO:0044428;nuclear part;4.75753059075216e-94!GO:0043233;organelle lumen;7.63446662729945e-92!GO:0031974;membrane-enclosed lumen;7.63446662729945e-92!GO:0003723;RNA binding;7.76218792685921e-85!GO:0005739;mitochondrion;2.02392745662285e-79!GO:0043283;biopolymer metabolic process;1.42312418894515e-69!GO:0010467;gene expression;3.07603821153524e-64!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;7.38041873976639e-63!GO:0005515;protein binding;2.2444778246167e-60!GO:0006396;RNA processing;3.80859530154427e-60!GO:0006412;translation;3.59813092486869e-58!GO:0031981;nuclear lumen;6.6450674942709e-58!GO:0043234;protein complex;1.87345311841662e-55!GO:0005840;ribosome;1.09335335351004e-54!GO:0044429;mitochondrial part;6.90011819455994e-54!GO:0019538;protein metabolic process;3.58612176403587e-53!GO:0009058;biosynthetic process;1.9105489755667e-51!GO:0044249;cellular biosynthetic process;1.31272717547672e-48!GO:0031967;organelle envelope;1.49382155248562e-48!GO:0031090;organelle membrane;2.10172524056873e-48!GO:0031975;envelope;3.93319283297412e-48!GO:0044267;cellular protein metabolic process;5.36617062009921e-48!GO:0016071;mRNA metabolic process;8.93019813153756e-48!GO:0003735;structural constituent of ribosome;1.41604479052728e-47!GO:0044260;cellular macromolecule metabolic process;3.22551001850813e-47!GO:0009059;macromolecule biosynthetic process;1.09388403798144e-46!GO:0003676;nucleic acid binding;2.60746873768887e-45!GO:0033036;macromolecule localization;5.33627467861073e-45!GO:0008380;RNA splicing;1.38804720323546e-42!GO:0015031;protein transport;7.47914527858732e-42!GO:0005829;cytosol;9.08981654444044e-42!GO:0006259;DNA metabolic process;2.0672192237606e-41!GO:0006397;mRNA processing;2.0672192237606e-41!GO:0016043;cellular component organization and biogenesis;2.32129338545992e-41!GO:0033279;ribosomal subunit;2.65112152443056e-41!GO:0008104;protein localization;2.13110189230085e-40!GO:0045184;establishment of protein localization;9.60246623389116e-40!GO:0065003;macromolecular complex assembly;3.66027676041748e-38!GO:0006996;organelle organization and biogenesis;2.21183797645432e-37!GO:0005654;nucleoplasm;4.04708719200336e-37!GO:0022613;ribonucleoprotein complex biogenesis and assembly;4.5448251156783e-37!GO:0046907;intracellular transport;4.1968339452521e-34!GO:0016070;RNA metabolic process;9.32083647014892e-34!GO:0005740;mitochondrial envelope;1.11637006844305e-32!GO:0043228;non-membrane-bound organelle;1.677478291703e-32!GO:0043232;intracellular non-membrane-bound organelle;1.677478291703e-32!GO:0022607;cellular component assembly;1.74091308221447e-32!GO:0019866;organelle inner membrane;8.80629641173219e-32!GO:0005681;spliceosome;2.86644401709729e-31!GO:0000166;nucleotide binding;4.65055913568816e-31!GO:0031966;mitochondrial membrane;1.58956722762885e-30!GO:0005830;cytosolic ribosome (sensu Eukaryota);7.02079342479345e-30!GO:0044445;cytosolic part;1.92388354294274e-29!GO:0007049;cell cycle;2.30768913139833e-29!GO:0044451;nucleoplasm part;3.62141363202313e-29!GO:0005743;mitochondrial inner membrane;4.41007274069823e-29!GO:0006886;intracellular protein transport;3.13250465328533e-28!GO:0051649;establishment of cellular localization;1.43609069230302e-26!GO:0031980;mitochondrial lumen;1.5923799743061e-26!GO:0005759;mitochondrial matrix;1.5923799743061e-26!GO:0051641;cellular localization;3.83333227734534e-26!GO:0006974;response to DNA damage stimulus;3.84752893037919e-23!GO:0016874;ligase activity;1.55703895451824e-22!GO:0022402;cell cycle process;2.09657323337374e-22!GO:0006119;oxidative phosphorylation;3.52078960374958e-22!GO:0032553;ribonucleotide binding;4.0364627805211e-22!GO:0032555;purine ribonucleotide binding;4.0364627805211e-22!GO:0015935;small ribosomal subunit;4.99739857017306e-22!GO:0000278;mitotic cell cycle;7.15857980213866e-22!GO:0005694;chromosome;9.94793778178818e-22!GO:0016462;pyrophosphatase activity;2.88710979971722e-21!GO:0005730;nucleolus;2.88710979971722e-21!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;3.56059186244798e-21!GO:0006281;DNA repair;3.93467118028738e-21!GO:0017076;purine nucleotide binding;4.56642343184235e-21!GO:0016817;hydrolase activity, acting on acid anhydrides;5.26801847450849e-21!GO:0044455;mitochondrial membrane part;8.30512916427805e-21!GO:0022618;protein-RNA complex assembly;8.57435407038938e-21!GO:0051276;chromosome organization and biogenesis;1.0425371917931e-20!GO:0005524;ATP binding;1.59257373057523e-20!GO:0015934;large ribosomal subunit;2.02378317210448e-20!GO:0032559;adenyl ribonucleotide binding;2.06935626708028e-20!GO:0017111;nucleoside-triphosphatase activity;2.52705928220045e-20!GO:0030554;adenyl nucleotide binding;4.32934052503418e-19!GO:0006512;ubiquitin cycle;4.80577165069887e-19!GO:0044427;chromosomal part;6.28665403444969e-19!GO:0012505;endomembrane system;7.62408340817851e-19!GO:0006457;protein folding;1.07719048619498e-18!GO:0044265;cellular macromolecule catabolic process;3.3876959078838e-18!GO:0022403;cell cycle phase;1.03110409844497e-17!GO:0008135;translation factor activity, nucleic acid binding;3.39456757690607e-17!GO:0005746;mitochondrial respiratory chain;4.86737653068116e-17!GO:0051186;cofactor metabolic process;6.91708891045518e-17!GO:0042254;ribosome biogenesis and assembly;8.15699429322113e-17!GO:0005635;nuclear envelope;1.06210954814739e-16!GO:0006325;establishment and/or maintenance of chromatin architecture;1.08729579739299e-16!GO:0048770;pigment granule;1.5004831089501e-16!GO:0042470;melanosome;1.5004831089501e-16!GO:0000087;M phase of mitotic cell cycle;2.88541784350224e-16!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);4.0329602139086e-16!GO:0016604;nuclear body;5.06359299246256e-16!GO:0006260;DNA replication;5.59219786821042e-16!GO:0008134;transcription factor binding;5.97723868761262e-16!GO:0007067;mitosis;6.20563864159016e-16!GO:0006323;DNA packaging;6.87068709492755e-16!GO:0006511;ubiquitin-dependent protein catabolic process;6.88471205246158e-16!GO:0044248;cellular catabolic process;7.02312459394089e-16!GO:0031965;nuclear membrane;7.12690457327592e-16!GO:0005761;mitochondrial ribosome;7.64722066140852e-16!GO:0000313;organellar ribosome;7.64722066140852e-16!GO:0043285;biopolymer catabolic process;7.7468270512505e-16!GO:0051603;proteolysis involved in cellular protein catabolic process;7.88204312204178e-16!GO:0019941;modification-dependent protein catabolic process;8.03114893485927e-16!GO:0043632;modification-dependent macromolecule catabolic process;8.03114893485927e-16!GO:0009719;response to endogenous stimulus;8.03114893485927e-16!GO:0016887;ATPase activity;1.18808206816347e-15!GO:0000398;nuclear mRNA splicing, via spliceosome;1.39053539503696e-15!GO:0000375;RNA splicing, via transesterification reactions;1.39053539503696e-15!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.39053539503696e-15!GO:0051301;cell division;1.46100871317204e-15!GO:0044453;nuclear membrane part;1.71064210729638e-15!GO:0043412;biopolymer modification;1.79974941744542e-15!GO:0050136;NADH dehydrogenase (quinone) activity;1.93031410349896e-15!GO:0003954;NADH dehydrogenase activity;1.93031410349896e-15!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.93031410349896e-15!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;2.04211896342255e-15!GO:0044257;cellular protein catabolic process;2.11303369692885e-15!GO:0042623;ATPase activity, coupled;5.34440268121495e-15!GO:0009057;macromolecule catabolic process;6.21568688837954e-15!GO:0000279;M phase;2.06255272294098e-14!GO:0000502;proteasome complex (sensu Eukaryota);2.10363692754367e-14!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);4.36738582506558e-14!GO:0006605;protein targeting;7.74554742512652e-14!GO:0006464;protein modification process;1.93579489350819e-13!GO:0003743;translation initiation factor activity;2.0234399730446e-13!GO:0042775;organelle ATP synthesis coupled electron transport;2.09982124510401e-13!GO:0042773;ATP synthesis coupled electron transport;2.09982124510401e-13!GO:0004386;helicase activity;2.23191982935362e-13!GO:0005643;nuclear pore;2.23387238965739e-13!GO:0030964;NADH dehydrogenase complex (quinone);2.35852517341111e-13!GO:0045271;respiratory chain complex I;2.35852517341111e-13!GO:0005747;mitochondrial respiratory chain complex I;2.35852517341111e-13!GO:0050657;nucleic acid transport;2.63566811282962e-13!GO:0051236;establishment of RNA localization;2.63566811282962e-13!GO:0050658;RNA transport;2.63566811282962e-13!GO:0006915;apoptosis;3.47346665162868e-13!GO:0051082;unfolded protein binding;3.63597614378509e-13!GO:0012501;programmed cell death;3.73149472242808e-13!GO:0006403;RNA localization;4.51766981280927e-13!GO:0006413;translational initiation;5.87699698519644e-13!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;8.34828701689851e-13!GO:0006399;tRNA metabolic process;9.63583911721205e-13!GO:0006732;coenzyme metabolic process;1.14201226185948e-12!GO:0016607;nuclear speck;2.1478586359868e-12!GO:0048193;Golgi vesicle transport;2.2093434297369e-12!GO:0008219;cell death;2.38711752696517e-12!GO:0016265;death;2.38711752696517e-12!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;3.03117702173479e-12!GO:0030163;protein catabolic process;3.16507883840429e-12!GO:0050794;regulation of cellular process;3.54701491010355e-12!GO:0065004;protein-DNA complex assembly;4.05146597371343e-12!GO:0016192;vesicle-mediated transport;6.19012284034671e-12!GO:0044432;endoplasmic reticulum part;1.04556291909399e-11!GO:0006364;rRNA processing;1.37751105592533e-11!GO:0043687;post-translational protein modification;1.39176163634474e-11!GO:0051188;cofactor biosynthetic process;1.44331692329119e-11!GO:0005783;endoplasmic reticulum;1.79994435294399e-11!GO:0008026;ATP-dependent helicase activity;2.25390309303618e-11!GO:0016072;rRNA metabolic process;2.58632488035193e-11!GO:0065002;intracellular protein transport across a membrane;2.7614350784097e-11!GO:0051028;mRNA transport;2.92788416704309e-11!GO:0051726;regulation of cell cycle;3.33461077661583e-11!GO:0016568;chromatin modification;3.36497919947745e-11!GO:0006913;nucleocytoplasmic transport;3.8926387956218e-11!GO:0000074;regulation of progression through cell cycle;3.94929130316565e-11!GO:0006446;regulation of translational initiation;4.19531971866323e-11!GO:0046930;pore complex;4.30503482966156e-11!GO:0000785;chromatin;4.62042470596628e-11!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;6.28871640249837e-11!GO:0051169;nuclear transport;7.70716422020519e-11!GO:0003712;transcription cofactor activity;7.87548746877013e-11!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.64937693313366e-10!GO:0004812;aminoacyl-tRNA ligase activity;1.64937693313366e-10!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.64937693313366e-10!GO:0006333;chromatin assembly or disassembly;1.8961857942039e-10!GO:0006461;protein complex assembly;2.37362673770812e-10!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;2.52340244358013e-10!GO:0016740;transferase activity;2.98009658548302e-10!GO:0019222;regulation of metabolic process;4.17074723492246e-10!GO:0043038;amino acid activation;4.17334017552793e-10!GO:0006418;tRNA aminoacylation for protein translation;4.17334017552793e-10!GO:0043039;tRNA aminoacylation;4.17334017552793e-10!GO:0005794;Golgi apparatus;5.31961843326809e-10!GO:0008565;protein transporter activity;6.97401253233371e-10!GO:0006163;purine nucleotide metabolic process;6.97401253233371e-10!GO:0006164;purine nucleotide biosynthetic process;1.13536618596269e-09!GO:0009259;ribonucleotide metabolic process;1.19502365337273e-09!GO:0016779;nucleotidyltransferase activity;1.50749556574343e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;2.21090462786303e-09!GO:0006366;transcription from RNA polymerase II promoter;2.83452695330392e-09!GO:0008639;small protein conjugating enzyme activity;4.50074062590835e-09!GO:0009260;ribonucleotide biosynthetic process;5.01346047991952e-09!GO:0042175;nuclear envelope-endoplasmic reticulum network;5.56288939831309e-09!GO:0009150;purine ribonucleotide metabolic process;5.89936127508799e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;6.02960066957161e-09!GO:0009056;catabolic process;6.60752529649782e-09!GO:0050789;regulation of biological process;6.96680672154727e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;8.32816768392001e-09!GO:0009152;purine ribonucleotide biosynthetic process;9.65178497445021e-09!GO:0030532;small nuclear ribonucleoprotein complex;1.01752936329547e-08!GO:0004842;ubiquitin-protein ligase activity;1.04047463962648e-08!GO:0005789;endoplasmic reticulum membrane;1.05263933251653e-08!GO:0003697;single-stranded DNA binding;1.08288695682131e-08!GO:0009060;aerobic respiration;1.08288695682131e-08!GO:0017038;protein import;1.52847431201592e-08!GO:0016787;hydrolase activity;1.81634709580131e-08!GO:0015986;ATP synthesis coupled proton transport;3.10376670694408e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;3.10376670694408e-08!GO:0019787;small conjugating protein ligase activity;3.61553684650749e-08!GO:0043566;structure-specific DNA binding;4.22143461351563e-08!GO:0019829;cation-transporting ATPase activity;4.48662535150034e-08!GO:0009108;coenzyme biosynthetic process;6.17266526441217e-08!GO:0006261;DNA-dependent DNA replication;8.09438823122182e-08!GO:0031323;regulation of cellular metabolic process;8.4020321365439e-08!GO:0005819;spindle;9.09439769638581e-08!GO:0006334;nucleosome assembly;1.26456036656292e-07!GO:0015078;hydrogen ion transmembrane transporter activity;1.27238991239804e-07!GO:0006793;phosphorus metabolic process;1.30037019488568e-07!GO:0006796;phosphate metabolic process;1.30037019488568e-07!GO:0009142;nucleoside triphosphate biosynthetic process;1.43884389567537e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.43884389567537e-07!GO:0005793;ER-Golgi intermediate compartment;1.44033054829867e-07!GO:0000775;chromosome, pericentric region;1.48999457773352e-07!GO:0007005;mitochondrion organization and biogenesis;1.49047167760755e-07!GO:0051246;regulation of protein metabolic process;1.55405717041897e-07!GO:0009055;electron carrier activity;1.67365407978731e-07!GO:0042981;regulation of apoptosis;1.70786000135439e-07!GO:0016881;acid-amino acid ligase activity;1.72004210501657e-07!GO:0006350;transcription;1.94765491729555e-07!GO:0009199;ribonucleoside triphosphate metabolic process;1.99442114849328e-07!GO:0009141;nucleoside triphosphate metabolic process;2.16298874906305e-07!GO:0003713;transcription coactivator activity;2.28223362524671e-07!GO:0045333;cellular respiration;2.28223362524671e-07!GO:0031497;chromatin assembly;2.28223362524671e-07!GO:0043067;regulation of programmed cell death;2.31948623167657e-07!GO:0048475;coated membrane;2.39615731147702e-07!GO:0030117;membrane coat;2.39615731147702e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.414500658308e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.414500658308e-07!GO:0000245;spliceosome assembly;2.96209749650868e-07!GO:0006754;ATP biosynthetic process;3.0697209529906e-07!GO:0006753;nucleoside phosphate metabolic process;3.0697209529906e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;3.3265738587522e-07!GO:0009144;purine nucleoside triphosphate metabolic process;3.3265738587522e-07!GO:0051329;interphase of mitotic cell cycle;3.64544096788262e-07!GO:0015630;microtubule cytoskeleton;4.29420736320564e-07!GO:0016310;phosphorylation;4.43062414520198e-07!GO:0005768;endosome;4.98925009614163e-07!GO:0003899;DNA-directed RNA polymerase activity;5.0649857759679e-07!GO:0006099;tricarboxylic acid cycle;6.27320971607427e-07!GO:0046356;acetyl-CoA catabolic process;6.27320971607427e-07!GO:0046034;ATP metabolic process;6.44154582535622e-07!GO:0045259;proton-transporting ATP synthase complex;7.01441840546545e-07!GO:0031202;RNA splicing factor activity, transesterification mechanism;8.35959632445483e-07!GO:0051325;interphase;8.68628077398764e-07!GO:0006084;acetyl-CoA metabolic process;1.10185656239517e-06!GO:0032446;protein modification by small protein conjugation;1.24637713862269e-06!GO:0016469;proton-transporting two-sector ATPase complex;1.27508883876522e-06!GO:0005813;centrosome;1.60280241508145e-06!GO:0005667;transcription factor complex;1.61925077712479e-06!GO:0006888;ER to Golgi vesicle-mediated transport;2.21017462480888e-06!GO:0005815;microtubule organizing center;2.21696650456504e-06!GO:0016567;protein ubiquitination;2.23026007516156e-06!GO:0006082;organic acid metabolic process;2.3836975585772e-06!GO:0019752;carboxylic acid metabolic process;2.39751342024435e-06!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;2.5241965024298e-06!GO:0010468;regulation of gene expression;2.65376838695686e-06!GO:0016563;transcription activator activity;3.22186822890844e-06!GO:0005762;mitochondrial large ribosomal subunit;3.78289902753511e-06!GO:0000315;organellar large ribosomal subunit;3.78289902753511e-06!GO:0006752;group transfer coenzyme metabolic process;3.90869973720229e-06!GO:0005839;proteasome core complex (sensu Eukaryota);4.05460544564745e-06!GO:0030120;vesicle coat;4.07437587277915e-06!GO:0030662;coated vesicle membrane;4.07437587277915e-06!GO:0000151;ubiquitin ligase complex;5.10164118208524e-06!GO:0048523;negative regulation of cellular process;5.55727441741451e-06!GO:0008654;phospholipid biosynthetic process;5.85122926264563e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;6.1203649012657e-06!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;6.63500579523974e-06!GO:0008094;DNA-dependent ATPase activity;7.05327354235651e-06!GO:0003724;RNA helicase activity;7.84459106162826e-06!GO:0000075;cell cycle checkpoint;8.25733608503496e-06!GO:0005657;replication fork;8.5195491109676e-06!GO:0051168;nuclear export;8.73072942187476e-06!GO:0009109;coenzyme catabolic process;9.12243531053054e-06!GO:0044452;nucleolar part;9.26575413639235e-06!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;9.49001480339072e-06!GO:0043069;negative regulation of programmed cell death;9.58431558815493e-06!GO:0006302;double-strand break repair;9.6617926585713e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;1.00937902710397e-05!GO:0043066;negative regulation of apoptosis;1.13577555816405e-05!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.1407766061138e-05!GO:0032774;RNA biosynthetic process;1.26845159843827e-05!GO:0008610;lipid biosynthetic process;1.41325888018239e-05!GO:0006613;cotranslational protein targeting to membrane;1.46021370090424e-05!GO:0051170;nuclear import;1.61653060138924e-05!GO:0006401;RNA catabolic process;1.61801000389675e-05!GO:0065007;biological regulation;1.63207384056272e-05!GO:0004298;threonine endopeptidase activity;1.6547966847771e-05!GO:0016363;nuclear matrix;1.67584797943918e-05!GO:0006351;transcription, DNA-dependent;1.70370079154505e-05!GO:0008270;zinc ion binding;1.87580026372858e-05!GO:0003677;DNA binding;1.91067939631592e-05!GO:0051187;cofactor catabolic process;1.91374946195786e-05!GO:0009117;nucleotide metabolic process;2.83072177490798e-05!GO:0006606;protein import into nucleus;2.88847196193217e-05!GO:0003729;mRNA binding;2.93431635548578e-05!GO:0005770;late endosome;3.04451230752997e-05!GO:0006402;mRNA catabolic process;3.47243533344979e-05!GO:0006310;DNA recombination;3.50481447210837e-05!GO:0007249;I-kappaB kinase/NF-kappaB cascade;3.51793027964833e-05!GO:0006916;anti-apoptosis;3.63539210931018e-05!GO:0051427;hormone receptor binding;3.86121044825076e-05!GO:0006352;transcription initiation;3.90149016955817e-05!GO:0031988;membrane-bound vesicle;4.62948477185594e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;5.200147998142e-05!GO:0016853;isomerase activity;5.90085402905573e-05!GO:0007051;spindle organization and biogenesis;6.15724676356185e-05!GO:0043623;cellular protein complex assembly;6.15724676356185e-05!GO:0000314;organellar small ribosomal subunit;7.13379200363561e-05!GO:0005763;mitochondrial small ribosomal subunit;7.13379200363561e-05!GO:0031982;vesicle;7.32951828998534e-05!GO:0003690;double-stranded DNA binding;7.38851199414019e-05!GO:0048519;negative regulation of biological process;7.38851199414019e-05!GO:0035257;nuclear hormone receptor binding;7.4160298500139e-05!GO:0044431;Golgi apparatus part;7.92381624558446e-05!GO:0004527;exonuclease activity;8.51470503584176e-05!GO:0046914;transition metal ion binding;8.87915257426944e-05!GO:0016491;oxidoreductase activity;9.40173445711866e-05!GO:0043021;ribonucleoprotein binding;0.000100652188852645!GO:0046483;heterocycle metabolic process;0.000129331577831156!GO:0005773;vacuole;0.000136212134812945!GO:0016023;cytoplasmic membrane-bound vesicle;0.000144577297993407!GO:0019899;enzyme binding;0.000146596212264519!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000151707412884272!GO:0045786;negative regulation of progression through cell cycle;0.000159019986936555!GO:0003678;DNA helicase activity;0.000165879947219858!GO:0016741;transferase activity, transferring one-carbon groups;0.000171261491051599!GO:0006779;porphyrin biosynthetic process;0.000171261491051599!GO:0033014;tetrapyrrole biosynthetic process;0.000171261491051599!GO:0031968;organelle outer membrane;0.000171789025181569!GO:0008168;methyltransferase activity;0.000177567410140127!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000186208266151326!GO:0030880;RNA polymerase complex;0.000192691937997975!GO:0006612;protein targeting to membrane;0.000198315863200089!GO:0005798;Golgi-associated vesicle;0.00020215562036648!GO:0000776;kinetochore;0.000205770665198989!GO:0043681;protein import into mitochondrion;0.00020900183048843!GO:0019867;outer membrane;0.000214948335836445!GO:0006839;mitochondrial transport;0.00021526033112969!GO:0008033;tRNA processing;0.000216575854861025!GO:0005741;mitochondrial outer membrane;0.00022636632231111!GO:0016859;cis-trans isomerase activity;0.000230905862577096!GO:0005525;GTP binding;0.000240381445744128!GO:0045449;regulation of transcription;0.00024388727394018!GO:0006383;transcription from RNA polymerase III promoter;0.000247502279807989!GO:0006338;chromatin remodeling;0.000259942736705873!GO:0044440;endosomal part;0.000259942736705873!GO:0010008;endosome membrane;0.000259942736705873!GO:0003684;damaged DNA binding;0.000261892586406325!GO:0003682;chromatin binding;0.000278856651958018!GO:0006091;generation of precursor metabolites and energy;0.000280048987899472!GO:0045045;secretory pathway;0.000292025294600693!GO:0031410;cytoplasmic vesicle;0.000297556301110783!GO:0005788;endoplasmic reticulum lumen;0.000310164050803202!GO:0006950;response to stress;0.000310164050803202!GO:0000323;lytic vacuole;0.000312649089960955!GO:0005764;lysosome;0.000312649089960955!GO:0019843;rRNA binding;0.000317608491546396!GO:0007059;chromosome segregation;0.000337317182847873!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000345339378157448!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000355678917889877!GO:0006405;RNA export from nucleus;0.00036100857176176!GO:0004518;nuclease activity;0.000362532493964038!GO:0005885;Arp2/3 protein complex;0.00036694042213051!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.00036694042213051!GO:0015399;primary active transmembrane transporter activity;0.00036694042213051!GO:0006520;amino acid metabolic process;0.000391406141339233!GO:0000059;protein import into nucleus, docking;0.000398315679361392!GO:0006626;protein targeting to mitochondrion;0.000398564100670001!GO:0006778;porphyrin metabolic process;0.000411308101062388!GO:0033013;tetrapyrrole metabolic process;0.000411308101062388!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00041978464282455!GO:0000428;DNA-directed RNA polymerase complex;0.00041978464282455!GO:0008186;RNA-dependent ATPase activity;0.00041978464282455!GO:0003924;GTPase activity;0.000447492202758977!GO:0006414;translational elongation;0.000462787815959696!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000481388857686137!GO:0022890;inorganic cation transmembrane transporter activity;0.000491886674927842!GO:0032508;DNA duplex unwinding;0.000497581489599212!GO:0032392;DNA geometric change;0.000497581489599212!GO:0006783;heme biosynthetic process;0.000508950354215404!GO:0044255;cellular lipid metabolic process;0.000511893142902095!GO:0016281;eukaryotic translation initiation factor 4F complex;0.000511893142902095!GO:0031072;heat shock protein binding;0.000511893142902095!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000511893142902095!GO:0006650;glycerophospholipid metabolic process;0.000550960820934446!GO:0065009;regulation of a molecular function;0.000552376181166772!GO:0007243;protein kinase cascade;0.000554497409950439!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.000591039589263473!GO:0030118;clathrin coat;0.000592762727969095!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000607721623849821!GO:0000786;nucleosome;0.000617488018839112!GO:0007006;mitochondrial membrane organization and biogenesis;0.000667979351934509!GO:0046474;glycerophospholipid biosynthetic process;0.000670252243833148!GO:0045454;cell redox homeostasis;0.000756199905368846!GO:0048471;perinuclear region of cytoplasm;0.000758264719831292!GO:0007088;regulation of mitosis;0.000783407161291304!GO:0005769;early endosome;0.000825196352547941!GO:0006268;DNA unwinding during replication;0.000832145346228327!GO:0000049;tRNA binding;0.000833373538340834!GO:0005637;nuclear inner membrane;0.000877588488033075!GO:0015992;proton transport;0.000882875881419482!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000940899541771537!GO:0007093;mitotic cell cycle checkpoint;0.000946361582721!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000961515348370582!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000961515348370582!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000961515348370582!GO:0051052;regulation of DNA metabolic process;0.00097208658956831!GO:0006818;hydrogen transport;0.00104310715427519!GO:0051252;regulation of RNA metabolic process;0.00107712468684317!GO:0006417;regulation of translation;0.00111299150944329!GO:0000139;Golgi membrane;0.00114763539478318!GO:0046467;membrane lipid biosynthetic process;0.00114763539478318!GO:0009165;nucleotide biosynthetic process;0.00115178501442053!GO:0004004;ATP-dependent RNA helicase activity;0.00118710165678972!GO:0031324;negative regulation of cellular metabolic process;0.00119087396981996!GO:0051920;peroxiredoxin activity;0.00123334651762022!GO:0042168;heme metabolic process;0.00132344428093078!GO:0016251;general RNA polymerase II transcription factor activity;0.00143676357193943!GO:0008047;enzyme activator activity;0.00148242055400195!GO:0030521;androgen receptor signaling pathway;0.00148745344300403!GO:0000922;spindle pole;0.00149799353175059!GO:0016197;endosome transport;0.00150378195322542!GO:0005684;U2-dependent spliceosome;0.0015324467166543!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00155680598178689!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00155680598178689!GO:0000082;G1/S transition of mitotic cell cycle;0.00156909062336115!GO:0032561;guanyl ribonucleotide binding;0.00158600300448404!GO:0019001;guanyl nucleotide binding;0.00158600300448404!GO:0006633;fatty acid biosynthetic process;0.00167180598993019!GO:0003714;transcription corepressor activity;0.00167180598993019!GO:0008234;cysteine-type peptidase activity;0.00168247375244309!GO:0032940;secretion by cell;0.00170456591644604!GO:0030384;phosphoinositide metabolic process;0.00171339069422558!GO:0006355;regulation of transcription, DNA-dependent;0.00173778360268829!GO:0008632;apoptotic program;0.00177300502706653!GO:0043492;ATPase activity, coupled to movement of substances;0.00183343785464259!GO:0005048;signal sequence binding;0.00192941611741518!GO:0015631;tubulin binding;0.00194356595090756!GO:0048500;signal recognition particle;0.00197881002926675!GO:0047485;protein N-terminus binding;0.00207804582789489!GO:0000096;sulfur amino acid metabolic process;0.0023582420016767!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00235828225970668!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0023710357425428!GO:0007052;mitotic spindle organization and biogenesis;0.00242410086529118!GO:0030867;rough endoplasmic reticulum membrane;0.00251627122717493!GO:0046394;carboxylic acid biosynthetic process;0.00256059756246061!GO:0016053;organic acid biosynthetic process;0.00256059756246061!GO:0042393;histone binding;0.0026114541036869!GO:0006284;base-excision repair;0.00264765628946311!GO:0006643;membrane lipid metabolic process;0.00267528022335804!GO:0043488;regulation of mRNA stability;0.00281849079549328!GO:0043487;regulation of RNA stability;0.00281849079549328!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.0028267566282056!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00289244714756764!GO:0005669;transcription factor TFIID complex;0.00295103801047829!GO:0003711;transcription elongation regulator activity;0.00305239058908145!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00307526635389914!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00318682306268578!GO:0016564;transcription repressor activity;0.00332370762212486!GO:0009081;branched chain family amino acid metabolic process;0.00344907252037941!GO:0030658;transport vesicle membrane;0.0034705937385977!GO:0007264;small GTPase mediated signal transduction;0.00350335957875661!GO:0006979;response to oxidative stress;0.00355450866180377!GO:0006519;amino acid and derivative metabolic process;0.00356219995618085!GO:0006891;intra-Golgi vesicle-mediated transport;0.00357947264466786!GO:0015980;energy derivation by oxidation of organic compounds;0.00370742654731944!GO:0030218;erythrocyte differentiation;0.00383586026428619!GO:0016126;sterol biosynthetic process;0.00397140147415855!GO:0006595;polyamine metabolic process;0.0040755502370686!GO:0004576;oligosaccharyl transferase activity;0.00409791635320938!GO:0046489;phosphoinositide biosynthetic process;0.00428842417557719!GO:0032984;macromolecular complex disassembly;0.00441803249919078!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00450398496310195!GO:0030119;AP-type membrane coat adaptor complex;0.00453440472335386!GO:0008276;protein methyltransferase activity;0.00453440472335386!GO:0050790;regulation of catalytic activity;0.00454850702690938!GO:0031252;leading edge;0.00461355134117281!GO:0008312;7S RNA binding;0.00463220229235323!GO:0009892;negative regulation of metabolic process;0.00470672834348584!GO:0006730;one-carbon compound metabolic process;0.00472397141444289!GO:0051287;NAD binding;0.00476016036541747!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00479498495625412!GO:0016584;nucleosome positioning;0.00486121876418499!GO:0042802;identical protein binding;0.00489729104252276!GO:0005791;rough endoplasmic reticulum;0.00495687984754995!GO:0016481;negative regulation of transcription;0.00517278397281753!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00517697288918701!GO:0045047;protein targeting to ER;0.00517697288918701!GO:0006270;DNA replication initiation;0.00522258294549401!GO:0031124;mRNA 3'-end processing;0.00528312174710794!GO:0032259;methylation;0.00536039145530854!GO:0015036;disulfide oxidoreductase activity;0.00539763659648456!GO:0006289;nucleotide-excision repair;0.00546470883963101!GO:0018193;peptidyl-amino acid modification;0.00555757303611738!GO:0043414;biopolymer methylation;0.00561128700494071!GO:0005876;spindle microtubule;0.00575588455959994!GO:0051087;chaperone binding;0.00591006673184141!GO:0008250;oligosaccharyl transferase complex;0.0059126565588368!GO:0006144;purine base metabolic process;0.0059751634388455!GO:0006644;phospholipid metabolic process;0.00597613041120185!GO:0043241;protein complex disassembly;0.00609458460569272!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00632074299680057!GO:0016746;transferase activity, transferring acyl groups;0.00632518812069464!GO:0016747;transferase activity, transferring groups other than amino-acyl groups;0.00638122122769337!GO:0030131;clathrin adaptor complex;0.00639951032347341!GO:0030518;steroid hormone receptor signaling pathway;0.00641961403475242!GO:0031326;regulation of cellular biosynthetic process;0.00672786741319903!GO:0046456;icosanoid biosynthetic process;0.00692128473380879!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00692128473380879!GO:0006695;cholesterol biosynthetic process;0.00706544543734589!GO:0008415;acyltransferase activity;0.007211959162325!GO:0000178;exosome (RNase complex);0.00740964682672313!GO:0019372;lipoxygenase pathway;0.00796265450476831!GO:0008139;nuclear localization sequence binding;0.00810606256603628!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00811856332877032!GO:0035258;steroid hormone receptor binding;0.00822481091025361!GO:0016408;C-acyltransferase activity;0.00833330813379261!GO:0048487;beta-tubulin binding;0.00839162013345345!GO:0051789;response to protein stimulus;0.00839162013345345!GO:0006986;response to unfolded protein;0.00839162013345345!GO:0006611;protein export from nucleus;0.00867786786770733!GO:0016272;prefoldin complex;0.00873514720498487!GO:0006631;fatty acid metabolic process;0.00879587512511169!GO:0009112;nucleobase metabolic process;0.00881019421640112!GO:0008408;3'-5' exonuclease activity;0.0088701275631538!GO:0030660;Golgi-associated vesicle membrane;0.00895155142315686!GO:0032200;telomere organization and biogenesis;0.00895689733943582!GO:0000723;telomere maintenance;0.00895689733943582!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00929917198852051!GO:0003746;translation elongation factor activity;0.00941910553138528!GO:0043596;nuclear replication fork;0.00951578041817843!GO:0005096;GTPase activator activity;0.0095229908814547!GO:0030134;ER to Golgi transport vesicle;0.00952946300263152!GO:0000725;recombinational repair;0.00957633659805734!GO:0000724;double-strand break repair via homologous recombination;0.00957633659805734!GO:0030663;COPI coated vesicle membrane;0.00963762184923635!GO:0030126;COPI vesicle coat;0.00963762184923635!GO:0043624;cellular protein complex disassembly;0.00980005787151033!GO:0022415;viral reproductive process;0.00981341370610557!GO:0030176;integral to endoplasmic reticulum membrane;0.00981716036116535!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00981716036116535!GO:0015002;heme-copper terminal oxidase activity;0.00981716036116535!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00981716036116535!GO:0004129;cytochrome-c oxidase activity;0.00981716036116535!GO:0051540;metal cluster binding;0.00995782748485087!GO:0051536;iron-sulfur cluster binding;0.00995782748485087!GO:0043284;biopolymer biosynthetic process;0.00998913179783614!GO:0022411;cellular component disassembly;0.0102239088257338!GO:0004674;protein serine/threonine kinase activity;0.0113808831026513!GO:0043022;ribosome binding;0.0114703784460279!GO:0005758;mitochondrial intermembrane space;0.0117120292076964!GO:0006807;nitrogen compound metabolic process;0.0119940692252762!GO:0005832;chaperonin-containing T-complex;0.0120930420575439!GO:0006376;mRNA splice site selection;0.0122007577298123!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0122007577298123!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0122007577298123!GO:0009967;positive regulation of signal transduction;0.0122007577298123!GO:0033116;ER-Golgi intermediate compartment membrane;0.0129634499910849!GO:0019079;viral genome replication;0.0135669648644508!GO:0000118;histone deacetylase complex;0.0135669648644508!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0137548662394556!GO:0006892;post-Golgi vesicle-mediated transport;0.0139181539940649!GO:0030127;COPII vesicle coat;0.0140372858840943!GO:0012507;ER to Golgi transport vesicle membrane;0.0140372858840943!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0142786379282927!GO:0031570;DNA integrity checkpoint;0.0142941306401078!GO:0007021;tubulin folding;0.0143254827205422!GO:0005874;microtubule;0.0143561300606493!GO:0042158;lipoprotein biosynthetic process;0.0143686674372391!GO:0009308;amine metabolic process;0.0144379097413399!GO:0030137;COPI-coated vesicle;0.0148377124676072!GO:0006406;mRNA export from nucleus;0.0149627512642829!GO:0016407;acetyltransferase activity;0.0150997072070695!GO:0044438;microbody part;0.0151015253065287!GO:0044439;peroxisomal part;0.0151015253065287!GO:0018196;peptidyl-asparagine modification;0.015523306270593!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.015523306270593!GO:0031123;RNA 3'-end processing;0.0156437656996358!GO:0009889;regulation of biosynthetic process;0.0157091061135227!GO:0004177;aminopeptidase activity;0.0159410339599533!GO:0045947;negative regulation of translational initiation;0.0160087681606281!GO:0004003;ATP-dependent DNA helicase activity;0.0160087681606281!GO:0007050;cell cycle arrest;0.0160467085415908!GO:0050662;coenzyme binding;0.0162702720443118!GO:0006672;ceramide metabolic process;0.0165123999239458!GO:0006378;mRNA polyadenylation;0.0167130027168574!GO:0000792;heterochromatin;0.0167890132605259!GO:0000339;RNA cap binding;0.0169536844126939!GO:0008637;apoptotic mitochondrial changes;0.0170022347527625!GO:0043189;H4/H2A histone acetyltransferase complex;0.0174614956089229!GO:0032039;integrator complex;0.0175740605523838!GO:0048037;cofactor binding;0.0176862546584786!GO:0009083;branched chain family amino acid catabolic process;0.0177911116258149!GO:0000819;sister chromatid segregation;0.0178634712984709!GO:0006629;lipid metabolic process;0.0179618621019196!GO:0016790;thiolester hydrolase activity;0.0183964219610005!GO:0030695;GTPase regulator activity;0.0186221962967875!GO:0044262;cellular carbohydrate metabolic process;0.0186221962967875!GO:0006607;NLS-bearing substrate import into nucleus;0.0186221962967875!GO:0000287;magnesium ion binding;0.0187367463824062!GO:0005774;vacuolar membrane;0.0188635666252039!GO:0046966;thyroid hormone receptor binding;0.0192912652755764!GO:0030522;intracellular receptor-mediated signaling pathway;0.0195391645257629!GO:0007040;lysosome organization and biogenesis;0.0198744669924333!GO:0030508;thiol-disulfide exchange intermediate activity;0.0199029442439509!GO:0009451;RNA modification;0.0200523428522395!GO:0035267;NuA4 histone acetyltransferase complex;0.0202664330035174!GO:0046519;sphingoid metabolic process;0.0209077340375596!GO:0016585;chromatin remodeling complex;0.0209316242723888!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0214856057637348!GO:0031903;microbody membrane;0.0214856057637348!GO:0005778;peroxisomal membrane;0.0214856057637348!GO:0004532;exoribonuclease activity;0.021503568859103!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.021503568859103!GO:0006497;protein amino acid lipidation;0.0216491947361483!GO:0003725;double-stranded RNA binding;0.0217509046321669!GO:0006275;regulation of DNA replication;0.0218580828769476!GO:0030132;clathrin coat of coated pit;0.0221909896106052!GO:0031902;late endosome membrane;0.0222684885056565!GO:0040029;regulation of gene expression, epigenetic;0.0223238190577953!GO:0051539;4 iron, 4 sulfur cluster binding;0.0224071290631943!GO:0000726;non-recombinational repair;0.022684182582165!GO:0000070;mitotic sister chromatid segregation;0.0226860581878318!GO:0009066;aspartate family amino acid metabolic process;0.0227189843513536!GO:0045815;positive regulation of gene expression, epigenetic;0.0229565401933029!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0231353098592705!GO:0007010;cytoskeleton organization and biogenesis;0.0233047406584202!GO:0003857;3-hydroxyacyl-CoA dehydrogenase activity;0.0233047406584202!GO:0031625;ubiquitin protein ligase binding;0.0239112177825654!GO:0031970;organelle envelope lumen;0.0239963746746406!GO:0006220;pyrimidine nucleotide metabolic process;0.0240269778542107!GO:0019783;small conjugating protein-specific protease activity;0.0244455046833884!GO:0022406;membrane docking;0.0244455046833884!GO:0048278;vesicle docking;0.0244455046833884!GO:0008097;5S rRNA binding;0.0246269219816035!GO:0009067;aspartate family amino acid biosynthetic process;0.0247339699716264!GO:0000097;sulfur amino acid biosynthetic process;0.0249293285002028!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0251708863827321!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0251887619568666!GO:0051053;negative regulation of DNA metabolic process;0.0253233477902896!GO:0007265;Ras protein signal transduction;0.0253233477902896!GO:0000123;histone acetyltransferase complex;0.0253233477902896!GO:0030133;transport vesicle;0.0255084615672667!GO:0001726;ruffle;0.0256808051609433!GO:0007017;microtubule-based process;0.0259682943211413!GO:0032787;monocarboxylic acid metabolic process;0.0259751433411221!GO:0008287;protein serine/threonine phosphatase complex;0.0261977427155825!GO:0007242;intracellular signaling cascade;0.0262031923871788!GO:0016605;PML body;0.0265001421452117!GO:0008144;drug binding;0.0265031462298194!GO:0043601;nuclear replisome;0.0267685162214124!GO:0030894;replisome;0.0267685162214124!GO:0006506;GPI anchor biosynthetic process;0.0269937131767415!GO:0008017;microtubule binding;0.0270622556416635!GO:0004843;ubiquitin-specific protease activity;0.0270622556416635!GO:0000228;nuclear chromosome;0.0271027480071816!GO:0009303;rRNA transcription;0.0272947323809325!GO:0000910;cytokinesis;0.0276046779886293!GO:0050178;phenylpyruvate tautomerase activity;0.0278391291965953!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0285005232135493!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0289441957229029!GO:0030496;midbody;0.0294379191267758!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.0305643185589877!GO:0043065;positive regulation of apoptosis;0.0309540400908846!GO:0006917;induction of apoptosis;0.0310940915711739!GO:0008213;protein amino acid alkylation;0.0310940915711739!GO:0006479;protein amino acid methylation;0.0310940915711739!GO:0006509;membrane protein ectodomain proteolysis;0.0325678224260657!GO:0033619;membrane protein proteolysis;0.0325678224260657!GO:0016835;carbon-oxygen lyase activity;0.0326777329036172!GO:0006596;polyamine biosynthetic process;0.0327292580165431!GO:0009124;nucleoside monophosphate biosynthetic process;0.0327292580165431!GO:0009123;nucleoside monophosphate metabolic process;0.0327292580165431!GO:0005869;dynactin complex;0.0327581989243273!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0327581989243273!GO:0006555;methionine metabolic process;0.0330207348429772!GO:0044450;microtubule organizing center part;0.0330227168695337!GO:0012506;vesicle membrane;0.0334153172151923!GO:0004300;enoyl-CoA hydratase activity;0.0334762616575584!GO:0030036;actin cytoskeleton organization and biogenesis;0.0334995273931411!GO:0006118;electron transport;0.0334995273931411!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0337449178391335!GO:0005765;lysosomal membrane;0.0337453490707526!GO:0006733;oxidoreduction coenzyme metabolic process;0.0337894865040054!GO:0042809;vitamin D receptor binding;0.0339436724921478!GO:0046128;purine ribonucleoside metabolic process;0.0339576355889153!GO:0042278;purine nucleoside metabolic process;0.0339576355889153!GO:0043068;positive regulation of programmed cell death;0.0340229692166101!GO:0031577;spindle checkpoint;0.0340972619115977!GO:0050681;androgen receptor binding;0.0345283604658863!GO:0031371;ubiquitin conjugating enzyme complex;0.0351414385252977!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.0351414385252977!GO:0006904;vesicle docking during exocytosis;0.0351820044480972!GO:0004428;inositol or phosphatidylinositol kinase activity;0.0351820044480972!GO:0005095;GTPase inhibitor activity;0.0352451111189871!GO:0012502;induction of programmed cell death;0.0352585267782757!GO:0000077;DNA damage checkpoint;0.035663392652416!GO:0004239;methionyl aminopeptidase activity;0.0359020246348678!GO:0048146;positive regulation of fibroblast proliferation;0.0359020246348678!GO:0006740;NADPH regeneration;0.0359731119614752!GO:0006098;pentose-phosphate shunt;0.0359731119614752!GO:0030125;clathrin vesicle coat;0.0361989945139995!GO:0030665;clathrin coated vesicle membrane;0.0361989945139995!GO:0007033;vacuole organization and biogenesis;0.0363182346598982!GO:0005652;nuclear lamina;0.0364217715310699!GO:0048144;fibroblast proliferation;0.0364217715310699!GO:0048145;regulation of fibroblast proliferation;0.0364217715310699!GO:0032287;myelin maintenance in the peripheral nervous system;0.0364217715310699!GO:0032838;cell projection cytoplasm;0.0364217715310699!GO:0033081;regulation of T cell differentiation in the thymus;0.0364217715310699!GO:0043217;myelin maintenance;0.0364217715310699!GO:0060087;relaxation of vascular smooth muscle;0.0364217715310699!GO:0032839;dendrite cytoplasm;0.0364217715310699!GO:0005784;translocon complex;0.0364809580479865!GO:0044437;vacuolar part;0.036792295671386!GO:0003887;DNA-directed DNA polymerase activity;0.0372058870812418!GO:0000152;nuclear ubiquitin ligase complex;0.0374086973134313!GO:0006360;transcription from RNA polymerase I promoter;0.0386751717835987!GO:0051338;regulation of transferase activity;0.0387568019270986!GO:0006505;GPI anchor metabolic process;0.0389064786860725!GO:0048522;positive regulation of cellular process;0.0389064786860725!GO:0003702;RNA polymerase II transcription factor activity;0.0391039507221237!GO:0030911;TPR domain binding;0.0393718494079327!GO:0004221;ubiquitin thiolesterase activity;0.0402525822492239!GO:0051235;maintenance of localization;0.0402817326403591!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0407601069914035!GO:0001784;phosphotyrosine binding;0.041632729270472!GO:0008180;signalosome;0.0416425590687305!GO:0000303;response to superoxide;0.0416425590687305!GO:0005521;lamin binding;0.0429613153332381!GO:0008652;amino acid biosynthetic process;0.0429613153332381!GO:0006007;glucose catabolic process;0.0430617189765999!GO:0016180;snRNA processing;0.0430983061441581!GO:0016073;snRNA metabolic process;0.0430983061441581!GO:0046588;negative regulation of calcium-dependent cell-cell adhesion;0.0435816193630272!GO:0046586;regulation of calcium-dependent cell-cell adhesion;0.0435816193630272!GO:0000209;protein polyubiquitination;0.0436326760883254!GO:0019206;nucleoside kinase activity;0.0441954690281555!GO:0006516;glycoprotein catabolic process;0.0444464166593689!GO:0007259;JAK-STAT cascade;0.0444464166593689!GO:0003756;protein disulfide isomerase activity;0.0445625516695435!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0445625516695435!GO:0006458;'de novo' protein folding;0.0446043851910519!GO:0051084;'de novo' posttranslational protein folding;0.0446043851910519!GO:0019377;glycolipid catabolic process;0.0446372405761536!GO:0017134;fibroblast growth factor binding;0.0447310554958498!GO:0016125;sterol metabolic process;0.0451057596008646!GO:0006301;postreplication repair;0.0452421572170915!GO:0042054;histone methyltransferase activity;0.0455826840144227!GO:0004523;ribonuclease H activity;0.0456235000749359!GO:0001516;prostaglandin biosynthetic process;0.0456865303454886!GO:0046457;prostanoid biosynthetic process;0.0456865303454886!GO:0030659;cytoplasmic vesicle membrane;0.0456865303454886!GO:0043549;regulation of kinase activity;0.0464775139652341!GO:0000781;chromosome, telomeric region;0.0466243651902451!GO:0005083;small GTPase regulator activity;0.0471394924383533!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0471488466546985!GO:0045039;protein import into mitochondrial inner membrane;0.0471488466546985!GO:0030041;actin filament polymerization;0.0490900671742249!GO:0060090;molecular adaptor activity;0.0495399375358433!GO:0046983;protein dimerization activity;0.0497627078257935 | |||
|sample_id=10766 | |sample_id=10766 | ||
|sample_note= | |sample_note= | ||
Line 76: | Line 99: | ||
|sample_tissue=blood | |sample_tissue=blood | ||
|top_motifs=GATA6:4.17008204007;RXR{A,B,G}_{NR1H2,PPAR}dimers:2.11985678087;MYB:1.8229187037;STAT5{A,B}:1.3485278103;ALX1:1.23365072813;IKZF2:1.1833228366;E2F1..5:1.1404376186;NR5A1,2:1.09104721728;BREu{core}:1.08418574388;ELF1,2,4:1.00925362292;NR6A1:1.00417466035;PAX6:0.965771252341;CRX:0.950687652493;bHLH_family:0.901762542753;PITX1..3:0.893101520166;YY1:0.890751223367;HOXA9_MEIS1:0.83146512954;PPARG:0.825172925548;POU3F1..4:0.81591769758;RORA:0.799328233738;ZNF143:0.778639436352;ZNF148:0.746208288411;EN1,2:0.740655917451;FOX{I1,J2}:0.739629718269;ELK1,4_GABP{A,B1}:0.735761971361;STAT1,3:0.733781937881;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.713435361619;CUX2:0.657750030999;POU2F1..3:0.654127298104;TLX2:0.642480551395;SPIB:0.639925784554;PAX8:0.599874306156;ZBTB16:0.596779010562;TOPORS:0.569358070754;PBX1:0.551987996454;SPI1:0.531111245927;RUNX1..3:0.464159473392;OCT4_SOX2{dimer}:0.420091969446;ETS1,2:0.4022903416;RBPJ:0.391642665344;PRRX1,2:0.371766385087;POU1F1:0.37039609928;NFY{A,B,C}:0.360961355022;NANOG{mouse}:0.358382841743;HES1:0.352842432834;HAND1,2:0.347030275771;SOX{8,9,10}:0.340002609232;HOX{A6,A7,B6,B7}:0.329783663568;FOXP1:0.295420471598;POU6F1:0.259346112191;TFDP1:0.232455966168;ONECUT1,2:0.22772545984;EVI1:0.226181447259;DMAP1_NCOR{1,2}_SMARC:0.215036304484;AR:0.205314575373;PAX4:0.188755375865;NKX2-3_NKX2-5:0.124551303494;NRF1:0.112993994541;HBP1_HMGB_SSRP1_UBTF:0.108790339798;FOXP3:0.0978834142508;NKX2-1,4:0.0808062399783;NANOG:0.0687734739105;PAX3,7:0.0662871089819;SMAD1..7,9:0.0660631330437;TEF:0.0528653115693;ADNP_IRX_SIX_ZHX:0.0129342631123;HNF4A_NR2F1,2:-0.0158433775217;GCM1,2:-0.015903064967;HOX{A5,B5}:-0.0282114708134;FOXN1:-0.0416884716618;T:-0.0565625622892;NKX3-1:-0.0744377138446;AIRE:-0.0758475051455;ZFP161:-0.085724248341;SOX17:-0.0935918374209;SNAI1..3:-0.0973873094046;REST:-0.104307817642;NKX2-2,8:-0.115206731583;AHR_ARNT_ARNT2:-0.122736552986;NHLH1,2:-0.130942090443;MTF1:-0.135615197408;ARID5B:-0.169820906053;CDX1,2,4:-0.177802093314;POU5F1:-0.180066676891;NFKB1_REL_RELA:-0.186413328532;FOXQ1:-0.204231007463;PAX2:-0.205454792895;NFIX:-0.207905991706;RXR{A,B,G}:-0.219495244138;GZF1:-0.239170469863;LHX3,4:-0.246863084892;BPTF:-0.248524044166;MYOD1:-0.252345833791;ZEB1:-0.263817019503;HNF1A:-0.271616090151;TGIF1:-0.290244273285;ATF5_CREB3:-0.295353606129;XBP1:-0.298356667212;RXRA_VDR{dimer}:-0.302067776835;FOXM1:-0.310132540408;ZNF423:-0.317482966966;FOX{F1,F2,J1}:-0.318337424439;NFE2:-0.326260354293;NKX6-1,2:-0.327455176944;DBP:-0.332808310058;KLF4:-0.336795561653;ZNF384:-0.355158142999;SREBF1,2:-0.376041298048;HIF1A:-0.415300799414;NR1H4:-0.42343840308;VSX1,2:-0.441926067205;TFAP4:-0.450362456071;RFX2..5_RFXANK_RFXAP:-0.456441592357;HSF1,2:-0.45678667255;TFAP2{A,C}:-0.470876930399;CREB1:-0.475812134975;HOX{A4,D4}:-0.495341119867;FOXD3:-0.507589551409;NFIL3:-0.507899477935;IRF1,2:-0.507901719326;SOX5:-0.514852161168;STAT2,4,6:-0.533487534411;ZBTB6:-0.565673517939;PDX1:-0.570848202687;BACH2:-0.572843184925;TFAP2B:-0.580989844182;EGR1..3:-0.58396181601;NFE2L1:-0.618460815642;FOS_FOS{B,L1}_JUN{B,D}:-0.619888877399;MED-1{core}:-0.630764014512;MYBL2:-0.644423150302;MEF2{A,B,C,D}:-0.651759458001;ATF4:-0.657344269118;FOXA2:-0.662185042001;ESR1:-0.669375225616;MYFfamily:-0.671418825629;MTE{core}:-0.685203081295;UFEwm:-0.685331875697;IRF7:-0.690108087302;GTF2I:-0.697175159655;CDC5L:-0.6983559116;SRF:-0.710974336342;HIC1:-0.723207187603;GFI1:-0.729478386922;NKX3-2:-0.73238514344;LEF1_TCF7_TCF7L1,2:-0.74154383171;TBX4,5:-0.766875889781;EBF1:-0.76713577769;HLF:-0.781457753325;NFE2L2:-0.806907397277;XCPE1{core}:-0.812020817978;CEBPA,B_DDIT3:-0.814769726589;FOSL2:-0.825951912995;HMGA1,2:-0.826435039764;GLI1..3:-0.831632090337;ESRRA:-0.841217237677;RREB1:-0.844191963421;RFX1:-0.856098007956;HMX1:-0.86217214087;IKZF1:-0.87132436389;PAX1,9:-0.874832039592;MZF1:-0.895483548983;EP300:-0.900581541622;FOXO1,3,4:-0.916407580159;FOX{D1,D2}:-0.938278065473;ZNF238:-0.938500782657;GTF2A1,2:-0.938747252679;LMO2:-0.948288473254;PAX5:-0.95742837798;PATZ1:-0.963507220345;NFATC1..3:-0.968313341115;TBP:-0.970656639069;GATA4:-0.982267465051;ATF2:-1.02183051599;TP53:-1.02184345469;TLX1..3_NFIC{dimer}:-1.07771658239;SOX2:-1.09356756968;ATF6:-1.10776394353;TEAD1:-1.12277580345;ZIC1..3:-1.12868566854;PRDM1:-1.14709999165;GFI1B:-1.17131141218;FOXL1:-1.17319088905;SP1:-1.2230279638;TAL1_TCF{3,4,12}:-1.23673648197;SPZ1:-1.25087629097;MAZ:-1.2794761358;ALX4:-1.28019059225;MAFB:-1.36626832486;NR3C1:-1.37562528425;TFCP2:-1.59034965965;JUN:-1.67375157407 | |top_motifs=GATA6:4.17008204007;RXR{A,B,G}_{NR1H2,PPAR}dimers:2.11985678087;MYB:1.8229187037;STAT5{A,B}:1.3485278103;ALX1:1.23365072813;IKZF2:1.1833228366;E2F1..5:1.1404376186;NR5A1,2:1.09104721728;BREu{core}:1.08418574388;ELF1,2,4:1.00925362292;NR6A1:1.00417466035;PAX6:0.965771252341;CRX:0.950687652493;bHLH_family:0.901762542753;PITX1..3:0.893101520166;YY1:0.890751223367;HOXA9_MEIS1:0.83146512954;PPARG:0.825172925548;POU3F1..4:0.81591769758;RORA:0.799328233738;ZNF143:0.778639436352;ZNF148:0.746208288411;EN1,2:0.740655917451;FOX{I1,J2}:0.739629718269;ELK1,4_GABP{A,B1}:0.735761971361;STAT1,3:0.733781937881;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.713435361619;CUX2:0.657750030999;POU2F1..3:0.654127298104;TLX2:0.642480551395;SPIB:0.639925784554;PAX8:0.599874306156;ZBTB16:0.596779010562;TOPORS:0.569358070754;PBX1:0.551987996454;SPI1:0.531111245927;RUNX1..3:0.464159473392;OCT4_SOX2{dimer}:0.420091969446;ETS1,2:0.4022903416;RBPJ:0.391642665344;PRRX1,2:0.371766385087;POU1F1:0.37039609928;NFY{A,B,C}:0.360961355022;NANOG{mouse}:0.358382841743;HES1:0.352842432834;HAND1,2:0.347030275771;SOX{8,9,10}:0.340002609232;HOX{A6,A7,B6,B7}:0.329783663568;FOXP1:0.295420471598;POU6F1:0.259346112191;TFDP1:0.232455966168;ONECUT1,2:0.22772545984;EVI1:0.226181447259;DMAP1_NCOR{1,2}_SMARC:0.215036304484;AR:0.205314575373;PAX4:0.188755375865;NKX2-3_NKX2-5:0.124551303494;NRF1:0.112993994541;HBP1_HMGB_SSRP1_UBTF:0.108790339798;FOXP3:0.0978834142508;NKX2-1,4:0.0808062399783;NANOG:0.0687734739105;PAX3,7:0.0662871089819;SMAD1..7,9:0.0660631330437;TEF:0.0528653115693;ADNP_IRX_SIX_ZHX:0.0129342631123;HNF4A_NR2F1,2:-0.0158433775217;GCM1,2:-0.015903064967;HOX{A5,B5}:-0.0282114708134;FOXN1:-0.0416884716618;T:-0.0565625622892;NKX3-1:-0.0744377138446;AIRE:-0.0758475051455;ZFP161:-0.085724248341;SOX17:-0.0935918374209;SNAI1..3:-0.0973873094046;REST:-0.104307817642;NKX2-2,8:-0.115206731583;AHR_ARNT_ARNT2:-0.122736552986;NHLH1,2:-0.130942090443;MTF1:-0.135615197408;ARID5B:-0.169820906053;CDX1,2,4:-0.177802093314;POU5F1:-0.180066676891;NFKB1_REL_RELA:-0.186413328532;FOXQ1:-0.204231007463;PAX2:-0.205454792895;NFIX:-0.207905991706;RXR{A,B,G}:-0.219495244138;GZF1:-0.239170469863;LHX3,4:-0.246863084892;BPTF:-0.248524044166;MYOD1:-0.252345833791;ZEB1:-0.263817019503;HNF1A:-0.271616090151;TGIF1:-0.290244273285;ATF5_CREB3:-0.295353606129;XBP1:-0.298356667212;RXRA_VDR{dimer}:-0.302067776835;FOXM1:-0.310132540408;ZNF423:-0.317482966966;FOX{F1,F2,J1}:-0.318337424439;NFE2:-0.326260354293;NKX6-1,2:-0.327455176944;DBP:-0.332808310058;KLF4:-0.336795561653;ZNF384:-0.355158142999;SREBF1,2:-0.376041298048;HIF1A:-0.415300799414;NR1H4:-0.42343840308;VSX1,2:-0.441926067205;TFAP4:-0.450362456071;RFX2..5_RFXANK_RFXAP:-0.456441592357;HSF1,2:-0.45678667255;TFAP2{A,C}:-0.470876930399;CREB1:-0.475812134975;HOX{A4,D4}:-0.495341119867;FOXD3:-0.507589551409;NFIL3:-0.507899477935;IRF1,2:-0.507901719326;SOX5:-0.514852161168;STAT2,4,6:-0.533487534411;ZBTB6:-0.565673517939;PDX1:-0.570848202687;BACH2:-0.572843184925;TFAP2B:-0.580989844182;EGR1..3:-0.58396181601;NFE2L1:-0.618460815642;FOS_FOS{B,L1}_JUN{B,D}:-0.619888877399;MED-1{core}:-0.630764014512;MYBL2:-0.644423150302;MEF2{A,B,C,D}:-0.651759458001;ATF4:-0.657344269118;FOXA2:-0.662185042001;ESR1:-0.669375225616;MYFfamily:-0.671418825629;MTE{core}:-0.685203081295;UFEwm:-0.685331875697;IRF7:-0.690108087302;GTF2I:-0.697175159655;CDC5L:-0.6983559116;SRF:-0.710974336342;HIC1:-0.723207187603;GFI1:-0.729478386922;NKX3-2:-0.73238514344;LEF1_TCF7_TCF7L1,2:-0.74154383171;TBX4,5:-0.766875889781;EBF1:-0.76713577769;HLF:-0.781457753325;NFE2L2:-0.806907397277;XCPE1{core}:-0.812020817978;CEBPA,B_DDIT3:-0.814769726589;FOSL2:-0.825951912995;HMGA1,2:-0.826435039764;GLI1..3:-0.831632090337;ESRRA:-0.841217237677;RREB1:-0.844191963421;RFX1:-0.856098007956;HMX1:-0.86217214087;IKZF1:-0.87132436389;PAX1,9:-0.874832039592;MZF1:-0.895483548983;EP300:-0.900581541622;FOXO1,3,4:-0.916407580159;FOX{D1,D2}:-0.938278065473;ZNF238:-0.938500782657;GTF2A1,2:-0.938747252679;LMO2:-0.948288473254;PAX5:-0.95742837798;PATZ1:-0.963507220345;NFATC1..3:-0.968313341115;TBP:-0.970656639069;GATA4:-0.982267465051;ATF2:-1.02183051599;TP53:-1.02184345469;TLX1..3_NFIC{dimer}:-1.07771658239;SOX2:-1.09356756968;ATF6:-1.10776394353;TEAD1:-1.12277580345;ZIC1..3:-1.12868566854;PRDM1:-1.14709999165;GFI1B:-1.17131141218;FOXL1:-1.17319088905;SP1:-1.2230279638;TAL1_TCF{3,4,12}:-1.23673648197;SPZ1:-1.25087629097;MAZ:-1.2794761358;ALX4:-1.28019059225;MAFB:-1.36626832486;NR3C1:-1.37562528425;TFCP2:-1.59034965965;JUN:-1.67375157407 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10766-110F1;search_select_hide=table117:FF:10766-110F1 | |||
}} | }} |
Latest revision as of 15:03, 3 June 2020
Name: | chronic myelogenous leukemia (CML) cell line:MEG-A2 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11865 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11865
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11865
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0686 |
10 | 10 | 0.0158 |
100 | 100 | 0.66 |
101 | 101 | 0.668 |
102 | 102 | 0.374 |
103 | 103 | 0.184 |
104 | 104 | 0.673 |
105 | 105 | 0.575 |
106 | 106 | 0.976 |
107 | 107 | 0.828 |
108 | 108 | 0.581 |
109 | 109 | 0.0125 |
11 | 11 | 0.0487 |
110 | 110 | 0.396 |
111 | 111 | 0.0318 |
112 | 112 | 0.399 |
113 | 113 | 0.581 |
114 | 114 | 0.134 |
115 | 115 | 0.135 |
116 | 116 | 0.103 |
117 | 117 | 0.0442 |
118 | 118 | 0.132 |
119 | 119 | 0.355 |
12 | 12 | 0.774 |
120 | 120 | 0.59 |
121 | 121 | 0.7 |
122 | 122 | 0.937 |
123 | 123 | 0.00784 |
124 | 124 | 0.576 |
125 | 125 | 0.0738 |
126 | 126 | 0.544 |
127 | 127 | 0.0865 |
128 | 128 | 0.887 |
129 | 129 | 0.721 |
13 | 13 | 0.00524 |
130 | 130 | 0.565 |
131 | 131 | 0.38 |
132 | 132 | 0.659 |
133 | 133 | 0.0449 |
134 | 134 | 0.67 |
135 | 135 | 0.396 |
136 | 136 | 0.0588 |
137 | 137 | 0.939 |
138 | 138 | 0.951 |
139 | 139 | 0.6 |
14 | 14 | 0.741 |
140 | 140 | 0.505 |
141 | 141 | 0.293 |
142 | 142 | 0.434 |
143 | 143 | 0.142 |
144 | 144 | 0.692 |
145 | 145 | 0.731 |
146 | 146 | 0.801 |
147 | 147 | 0.0513 |
148 | 148 | 0.956 |
149 | 149 | 0.167 |
15 | 15 | 0.235 |
150 | 150 | 0.812 |
151 | 151 | 0.816 |
152 | 152 | 0.677 |
153 | 153 | 0.842 |
154 | 154 | 0.816 |
155 | 155 | 0.0715 |
156 | 156 | 0.819 |
157 | 157 | 0.442 |
158 | 158 | 0.601 |
159 | 159 | 0.0968 |
16 | 16 | 0.957 |
160 | 160 | 0.432 |
161 | 161 | 0.287 |
162 | 162 | 0.873 |
163 | 163 | 0.284 |
164 | 164 | 0.0938 |
165 | 165 | 0.438 |
166 | 166 | 0.163 |
167 | 167 | 0.456 |
168 | 168 | 0.861 |
169 | 169 | 0.548 |
17 | 17 | 0.97 |
18 | 18 | 0.203 |
19 | 19 | 0.923 |
2 | 2 | 0.515 |
20 | 20 | 0.222 |
21 | 21 | 0.343 |
22 | 22 | 0.656 |
23 | 23 | 0.017 |
24 | 24 | 0.37 |
25 | 25 | 0.322 |
26 | 26 | 0.0938 |
27 | 27 | 0.948 |
28 | 28 | 0.738 |
29 | 29 | 0.0185 |
3 | 3 | 0.174 |
30 | 30 | 0.00941 |
31 | 31 | 0.368 |
32 | 32 | 0.0143 |
33 | 33 | 0.408 |
34 | 34 | 0.758 |
35 | 35 | 0.663 |
36 | 36 | 0.0335 |
37 | 37 | 0.271 |
38 | 38 | 0.364 |
39 | 39 | 0.42 |
4 | 4 | 0.294 |
40 | 40 | 0.315 |
41 | 41 | 0.345 |
42 | 42 | 0.396 |
43 | 43 | 0.62 |
44 | 44 | 0.791 |
45 | 45 | 0.686 |
46 | 46 | 0.321 |
47 | 47 | 0.0539 |
48 | 48 | 0.13 |
49 | 49 | 0.263 |
5 | 5 | 0.919 |
50 | 50 | 0.662 |
51 | 51 | 0.532 |
52 | 52 | 0.764 |
53 | 53 | 0.267 |
54 | 54 | 0.549 |
55 | 55 | 0.198 |
56 | 56 | 0.868 |
57 | 57 | 0.207 |
58 | 58 | 0.159 |
59 | 59 | 0.639 |
6 | 6 | 0.409 |
60 | 60 | 0.558 |
61 | 61 | 0.151 |
62 | 62 | 0.309 |
63 | 63 | 0.614 |
64 | 64 | 0.234 |
65 | 65 | 0.807 |
66 | 66 | 0.0264 |
67 | 67 | 0.992 |
68 | 68 | 0.123 |
69 | 69 | 0.824 |
7 | 7 | 0.0494 |
70 | 70 | 0.984 |
71 | 71 | 0.168 |
72 | 72 | 0.433 |
73 | 73 | 0.398 |
74 | 74 | 0.322 |
75 | 75 | 0.0118 |
76 | 76 | 0.161 |
77 | 77 | 0.376 |
78 | 78 | 0.00288 |
79 | 79 | 0.00635 |
8 | 8 | 0.134 |
80 | 80 | 0.49 |
81 | 81 | 0.553 |
82 | 82 | 0.33 |
83 | 83 | 0.576 |
84 | 84 | 0.591 |
85 | 85 | 0.0353 |
86 | 86 | 0.913 |
87 | 87 | 0.0219 |
88 | 88 | 0.198 |
89 | 89 | 0.687 |
9 | 9 | 0.93 |
90 | 90 | 0.0905 |
91 | 91 | 0.753 |
92 | 92 | 0.62 |
93 | 93 | 0.834 |
94 | 94 | 0.7 |
95 | 95 | 0.00407 |
96 | 96 | 0.635 |
97 | 97 | 0.448 |
98 | 98 | 0.0465 |
99 | 99 | 0.469 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11865
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
DOID:8552 chronic myeloid leukemia
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0100740 myeloid leukemia cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
1240 (leukemia)
8692 (myeloid leukemia)
8552 (chronic myeloid leukemia)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100737 (leukemia cell line sample)
0101035 (hematopoietic cell line sample)
0100740 (myeloid leukemia cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)