FF:10802-111A1: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005576 | ||
| | |accession_numbers=CAGE;DRX007821;DRR008693;DRZ000118;DRZ001503;DRZ011468;DRZ012853 | ||
| | |ancestors_in_anatomy_facet= | ||
| | |ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000255 | ||
| | |ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:14566,DOID:0060083,DOID:1240,DOID:8692 | ||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100737,FF:0101035,FF:0101883,FF:0100740 | |||
| | |comment= | ||
| | |created_by= | ||
|creation_date= | |||
|data_phase=2 | |||
| | |datafreeze_phase=2 | ||
| | |def= | ||
| | |expression_enrichment_score=chr12:54694758..54694805,-!p1@NFE2!2.69!590.74!NFE2;;chr6:135502501..135502546,+!p1@MYB!2.30!236.86!MYB;;chr12:54694807..54694832,-!p3@NFE2!2.23!167.77!NFE2;;chrX:48644984..48645005,+!p1@GATA1!2.19!152.27!GATA1;;chr3:128212033..128212051,-!p1@GATA2!1.98!94.46!GATA2;;chr5:3595977..3595999,+!p1@IRX1!1.97!91.64!IRX1;;chr3:128206762..128206781,-!p2@GATA2!1.87!430.01!GATA2;;chr9:20382446..20382493,-!p4@MLLT3!1.86!71.90!MLLT3;;chr5:3595934..3595957,+!p2@IRX1!1.77!57.80!IRX1;;chr21:39870339..39870443,-!p1@ERG!1.77!57.80!ERG;;chr12:54694653..54694672,-!p2@NFE2!1.76!56.39!NFE2;;chr12:54785074..54785122,-!p2@ZNF385A!1.75!83.18!ZNF385A;;chr5:3595961..3595975,+!p3@IRX1!1.69!47.94!IRX1;;chr5:88178983..88179012,-!p1@MEF2C!1.64!315.81!MEF2C;;chr9:135854091..135854159,+!p1@GFI1B!1.61!39.48!GFI1B;;chr1:61548225..61548299,+!p1@NFIA!1.59!472.31!NFIA;;chr6:135502472..135502489,+!p3@MYB!1.58!36.66!MYB;;chr17:40441354..40441410,+!p2@STAT5A!1.58!36.66!STAT5A;;chr19:12998003..12998021,-!p1@KLF1!1.58!36.66!KLF1;;chr19:13213511..13213545,-!p2@LYL1!1.52!35.25!LYL1;;chr7:50344289..50344323,+!p1@IKZF1!1.52!32.43!IKZF1;;chr12:54785054..54785072,-!p4@ZNF385A!1.51!35.25!ZNF385A;;chr12:54689532..54689551,-!p4@NFE2!1.51!31.02!NFE2;;chr1:92951607..92951661,-!p1@GFI1!1.51!31.02!GFI1;;chr10:94449703..94449718,+!p1@HHEX!1.49!112.79!HHEX;;chr19:58629742..58629787,-!p2@ZSCAN18!1.49!29.61!ZSCAN18;;chr10:94449675..94449694,+!p2@HHEX!1.40!63.44!HHEX;;chr19:9609272..9609297,-!p1@ZNF560!1.40!23.97!ZNF560;;chr1:47696918..47696935,-!p6@TAL1!1.40!23.97!TAL1;;chr1:61548069..61548102,+!p3@NFIA!1.38!54.98!NFIA;;chr4:4291837..4291859,-!p2@LYAR!1.32!63.44!LYAR;;chr20:31350184..31350200,+!p1@DNMT3B!1.32!40.89!DNMT3B;;chr20:50159198..50159299,-!p1@NFATC2!1.31!28.20!NFATC2;;chr12:54694738..54694749,-!p5@NFE2!1.29!18.33!NFE2;;chr5:88179017..88179046,-!p2@MEF2C!1.28!70.49!MEF2C;;chr1:61547894..61547968,+!p2@NFIA!1.28!52.17!NFIA;;chr6:10412392..10412409,-!p4@TFAP2A!1.26!19.74!TFAP2A;;chr21:36421535..36421610,-!p2@RUNX1!1.25!59.21!RUNX1;;chr7:137620650..137620677,-!p3@CREB3L2!1.25!16.92!CREB3L2;;chr6:135502408..135502459,+!p2@MYB!1.23!18.33!MYB;;chr11:65687362..65687436,+!p3@DRAP1!1.22!70.49!DRAP1;;chr12:54689552..54689574,-!p6@NFE2!1.22!15.51!NFE2;;chr2:242556880..242556899,-!p5@THAP4!1.22!15.51!THAP4;;chr2:242556900..242556916,-!p6@THAP4!1.22!15.51!THAP4;;chr7:137620684..137620711,-!p4@CREB3L2!1.22!15.51!CREB3L2;;chr10:98591801..98591841,+!p3@LCOR!1.21!21.15!LCOR;;chr19:58400344..58400364,-!p2@ZNF814!1.19!21.15!ZNF814;;chr19:58545454..58545498,+!p1@ZSCAN1!1.18!14.10!ZSCAN1;;chr17:38020392..38020477,-!p1@IKZF3!1.18!14.10!IKZF3;;chr6:28321909..28321965,-!p3@ZNF323!1.18!14.10!ZNF323;;chr3:128207349..128207386,-!p3@GATA2!1.18!14.10!GATA2;;chr3:63953435..63953499,+!p1@ATXN7!1.18!14.10!ATXN7;;chrX:48645010..48645015,+!p3@GATA1!1.18!14.10!GATA1;;chrX:48644976..48644983,+!p2@GATA1!1.18!14.10!GATA1;;chr19:42636586..42636607,-!p1@POU2F2!1.17!38.07!POU2F2;;chr11:47399947..47399961,-!p3@SPI1!1.14!12.69!SPI1;;chr6:10412576..10412599,-!p5@TFAP2A!1.14!12.69!TFAP2A;;chr19:58400372..58400411,-!p1@ZNF814!1.11!62.03!ZNF814;;chr17:40440481..40440550,+!p1@STAT5A!1.09!81.77!STAT5A;;chr1:92949331..92949377,-!p2@GFI1!1.09!11.28!GFI1;;chr7:50344251..50344288,+!p3@IKZF1!1.09!11.28!IKZF1;;chr6:10412600..10412637,-!p1@TFAP2A!1.08!18.33!TFAP2A;;chr6:21597600..21597664,+!p3@SOX4!1.08!18.33!SOX4;;chr15:57511609..57511651,+!p2@TCF12!1.07!18.33!TCF12;;chr19:11071685..11071798,+!p1@SMARCA4!1.06!297.48!SMARCA4;;chr3:18466787..18466839,-!p1@SATB1!1.06!47.94!SATB1;;chr19:33793430..33793447,-!p1@CEBPA!1.06!45.12!CEBPA;;chr10:94449649..94449664,+!p3@HHEX!1.06!15.51!HHEX;;chr16:88519669..88519726,+!p1@ZFPM1!1.04!90.23!ZFPM1;;chr19:57183114..57183145,-!p1@ZNF835!1.04!11.28!ZNF835;;chr19:13213555..13213568,-!p5@LYL1!1.04!9.87!LYL1;;chr5:88180342..88180365,-!p10@MEF2C!1.04!9.87!MEF2C;;chr9:124976328..124976372,-!p2@LHX6!1.04!9.87!LHX6;;chr11:47399996..47400014,-!p4@SPI1!1.04!9.87!SPI1;;chr11:47400078..47400106,-!p1@SPI1!1.04!9.87!SPI1;;chr12:54691711..54691725,-!p7@NFE2!1.04!9.87!NFE2;;chr13:79177703..79177729,-!p2@POU4F1!1.04!9.87!POU4F1;;chr2:60781201..60781258,-!p3@BCL11A!1.04!9.87!BCL11A;;chr2:145277640..145277771,-!p1@ZEB2!1.02!128.30!ZEB2;;chr19:22817119..22817145,+!p1@ZNF492!1.01!15.51!ZNF492;;chr12:11802753..11802834,+!p2@ETV6!1.00!45.12!ETV6;;chr22:42666593..42666623,-!p@chr22:42666593..42666623,-!1.00!21.15!TCF20;;chr19:47615426..47615439,-!p5@ZC3H4!0.99!21.15!ZC3H4;;chr5:88179195..88179224,-!p3@MEF2C!0.99!14.10!MEF2C;;chr6:126240463..126240489,+!p6@NCOA7!0.99!9.87!NCOA7;;chr19:36909484..36909525,-!p2@ZFP82!0.98!16.92!ZFP82;;chr19:13213465..13213478,-!p7@LYL1!0.98!8.46!LYL1;;chr19:22605136..22605154,-!p1@ZNF98!0.98!8.46!ZNF98;;chr7:50343634..50343717,+!p2@IKZF1!0.98!8.46!IKZF1;;chr7:63505799..63505904,+!p1@ZNF727!0.98!8.46!ZNF727;;chr1:47691303..47691319,-!p5@TAL1!0.98!8.46!TAL1;;chr1:47695003..47695042,-!p2@TAL1!0.98!8.46!TAL1;;chr19:37096139..37096170,-!p2@ZNF529!0.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| ||
| | |ffid_belonging_in_development=CL:0000049,CL:0000134 | ||
| | |||
| | |||
|fonse_cell_line=FF:0101035 | |fonse_cell_line=FF:0101035 | ||
|fonse_cell_line_closure=FF:0101035 | |fonse_cell_line_closure=FF:0101035 | ||
Line 66: | Line 40: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|top_motifs= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M7%2529%2520cell%2520line%253aMKPL-1.CNhs11888.10802-111A1.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M7%2529%2520cell%2520line%253aMKPL-1.CNhs11888.10802-111A1.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M7%2529%2520cell%2520line%253aMKPL-1.CNhs11888.10802-111A1.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M7%2529%2520cell%2520line%253aMKPL-1.CNhs11888.10802-111A1.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M7%2529%2520cell%2520line%253aMKPL-1.CNhs11888.10802-111A1.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10802-111A1 | |||
|is_a=EFO:0002091;;FF:0000210;;FF:0101883 | |||
|is_obsolete= | |||
|library_id=CNhs11888 | |||
|library_id_phase_based=2:CNhs11888 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10802 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10802 | |||
|name=acute myeloid leukemia (FAB M7) cell line:MKPL-1 | |||
|namespace=FANTOM5 | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs11888,LSID830,release010,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,-0.160318030086386,0,0.0376392541138844,0.12866347959035,0,0,0,0,0,0,0,0,0,0,0,0,0,0.228670614090344,0,0,0,0,0,-0.0979578962680575,0,0,-0.132956589778862,0,0,0,0,0,0,0,0,0,0,0,0,0.176530529357734,0,0,0,0,0,0,0,0,-0.0242150211128343,0,0,0,0,0,0,0,-0.0969923612426051,0,0,0.284649997225675,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0228185830636283,0,0,0,-0.0584468268118252,-0.0202005904764827,0,0,0,0,-0.0980353512377064,-0.138477200800895,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.096373593922461,0,0,0,0,0.100379531783948,0,0,0,0,0,0 | |||
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| |||
|rna_box=111 | |||
|rna_catalog_number= | |||
|rna_concentration=1.13606 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=2.14 | |||
|rna_od260/280=2.09 | |||
|rna_position=A1 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=111A1 | |||
|rna_weight_ug=53.39482 | |||
|sample_age=66 | |||
|sample_category=cell lines | |||
|sample_cell_catalog=jcrb1325 | |||
|sample_cell_line=MKPL-1 | |||
|sample_cell_lot= | |||
|sample_cell_type=myeloid progenitor cell | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=JAPAN HEALTH SCIENCES FOUNDATION - Health Science Research Resources Bank | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=acute myeloid leukemia (FAB M7) | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=J | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;2.67204962726468e-265!GO:0043227;membrane-bound organelle;2.37198099302204e-231!GO:0043231;intracellular membrane-bound organelle;9.0287110751164e-231!GO:0043226;organelle;2.35284165786152e-221!GO:0043229;intracellular organelle;2.05347605986616e-220!GO:0005737;cytoplasm;5.7777788725678e-147!GO:0044422;organelle part;2.38665062680203e-139!GO:0044446;intracellular organelle part;1.43733162709443e-137!GO:0005634;nucleus;3.0188669654303e-125!GO:0044237;cellular metabolic process;3.12230901508443e-123!GO:0044238;primary metabolic process;5.09527473476927e-117!GO:0043170;macromolecule metabolic process;1.56094959361281e-113!GO:0032991;macromolecular complex;1.25069503663942e-103!GO:0044444;cytoplasmic part;3.28530861264001e-101!GO:0044428;nuclear part;2.8069991561138e-90!GO:0030529;ribonucleoprotein complex;1.71151317039415e-87!GO:0043233;organelle lumen;4.49870885583376e-85!GO:0031974;membrane-enclosed lumen;4.49870885583376e-85!GO:0003723;RNA binding;9.34975058811211e-83!GO:0043283;biopolymer metabolic process;1.9155935128355e-74!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;6.87046886813558e-70!GO:0010467;gene expression;1.37426891559309e-68!GO:0005739;mitochondrion;3.43850520706049e-63!GO:0006396;RNA processing;1.56565775151074e-57!GO:0031981;nuclear lumen;6.69273183413002e-56!GO:0003676;nucleic acid binding;4.63481259488015e-52!GO:0043234;protein complex;2.17430608933533e-51!GO:0005515;protein binding;4.31675060762008e-50!GO:0006412;translation;2.88971087386304e-48!GO:0019538;protein metabolic process;1.03027468073825e-47!GO:0016071;mRNA metabolic process;1.15927514054475e-46!GO:0005840;ribosome;5.96398306783429e-46!GO:0044267;cellular protein metabolic process;7.62957882849747e-44!GO:0044260;cellular macromolecule metabolic process;1.66071718051166e-43!GO:0006259;DNA metabolic process;1.81215074947875e-43!GO:0044429;mitochondrial part;9.94689943317479e-43!GO:0008380;RNA splicing;1.25781683410388e-41!GO:0016043;cellular component organization and biogenesis;1.4029889954294e-41!GO:0003735;structural constituent of ribosome;6.55296566452877e-40!GO:0016070;RNA metabolic process;6.99678360923841e-40!GO:0006397;mRNA processing;1.48394231547931e-39!GO:0033036;macromolecule localization;1.55895677883283e-39!GO:0031090;organelle membrane;1.28473112973404e-38!GO:0031967;organelle envelope;4.56706007361141e-38!GO:0009059;macromolecule biosynthetic process;4.76041723190888e-38!GO:0031975;envelope;9.48707214841095e-38!GO:0009058;biosynthetic process;6.31582090556352e-37!GO:0015031;protein transport;8.28912742645947e-36!GO:0044249;cellular biosynthetic process;9.05694290801684e-36!GO:0006996;organelle organization and biogenesis;1.13506304539261e-35!GO:0022613;ribonucleoprotein complex biogenesis and assembly;3.48183505794974e-35!GO:0033279;ribosomal subunit;9.38176441716288e-35!GO:0005654;nucleoplasm;1.12233406352684e-34!GO:0008104;protein localization;3.54003362781144e-34!GO:0045184;establishment of protein localization;4.91092615081562e-34!GO:0065003;macromolecular complex assembly;6.1657317736614e-34!GO:0005829;cytosol;1.40950562026987e-33!GO:0000166;nucleotide binding;4.07000848800987e-32!GO:0005681;spliceosome;1.75983721497346e-30!GO:0043228;non-membrane-bound organelle;2.37402118359182e-30!GO:0043232;intracellular non-membrane-bound organelle;2.37402118359182e-30!GO:0022607;cellular component assembly;1.53722273623536e-29!GO:0046907;intracellular transport;1.26947194287894e-28!GO:0007049;cell cycle;5.74976952613762e-27!GO:0044451;nucleoplasm part;1.00288563611817e-26!GO:0005740;mitochondrial envelope;2.31625209418034e-25!GO:0005830;cytosolic ribosome (sensu Eukaryota);3.12981038715877e-25!GO:0006886;intracellular protein transport;3.45266609752802e-25!GO:0019866;organelle inner membrane;7.08300957016047e-25!GO:0051276;chromosome organization and biogenesis;2.80831823949631e-24!GO:0044445;cytosolic part;4.85477102937185e-24!GO:0031966;mitochondrial membrane;2.28561506672656e-23!GO:0016462;pyrophosphatase activity;2.88036075214039e-23!GO:0005730;nucleolus;3.1575994883131e-23!GO:0005743;mitochondrial inner membrane;3.81336476451919e-23!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;4.61586374750398e-23!GO:0017111;nucleoside-triphosphatase activity;5.09166423915275e-23!GO:0016817;hydrolase activity, acting on acid anhydrides;7.04068367624267e-23!GO:0051649;establishment of cellular localization;7.3970806974656e-23!GO:0006974;response to DNA damage stimulus;8.13057425383459e-23!GO:0005524;ATP binding;1.24900156070612e-22!GO:0051641;cellular localization;1.9994159764197e-22!GO:0032559;adenyl ribonucleotide binding;4.35234977089835e-22!GO:0032553;ribonucleotide binding;5.50847165447413e-22!GO:0032555;purine ribonucleotide binding;5.50847165447413e-22!GO:0022402;cell cycle process;1.3793011769488e-21!GO:0031980;mitochondrial lumen;2.24437581996605e-21!GO:0005759;mitochondrial matrix;2.24437581996605e-21!GO:0017076;purine nucleotide binding;4.13344547084572e-21!GO:0030554;adenyl nucleotide binding;8.03191944403074e-21!GO:0006281;DNA repair;1.0890142699061e-20!GO:0005694;chromosome;1.31267756681985e-20!GO:0006325;establishment and/or maintenance of chromatin architecture;4.34876874509302e-20!GO:0000278;mitotic cell cycle;1.07537101398689e-19!GO:0016887;ATPase activity;1.32380620168365e-19!GO:0006119;oxidative phosphorylation;1.37940658344167e-19!GO:0022618;protein-RNA complex assembly;2.51787399410484e-19!GO:0006323;DNA packaging;2.66014744900332e-19!GO:0006457;protein folding;4.51101191989805e-19!GO:0042623;ATPase activity, coupled;4.80896424756927e-19!GO:0044427;chromosomal part;7.95801345309019e-19!GO:0044455;mitochondrial membrane part;1.78287327565589e-18!GO:0016874;ligase activity;4.48383822994054e-18!GO:0015934;large ribosomal subunit;4.60477127555442e-18!GO:0016604;nuclear body;4.60477127555442e-18!GO:0044265;cellular macromolecule catabolic process;5.09298144063917e-18!GO:0015935;small ribosomal subunit;1.0989159843083e-17!GO:0006512;ubiquitin cycle;7.62998796529295e-17!GO:0043285;biopolymer catabolic process;9.63462204329089e-17!GO:0022403;cell cycle phase;1.05937015085693e-16!GO:0008134;transcription factor binding;2.27106967659866e-16!GO:0012505;endomembrane system;5.42507929195716e-16!GO:0042254;ribosome biogenesis and assembly;5.54577624348058e-16!GO:0009057;macromolecule catabolic process;9.0310237472845e-16!GO:0004386;helicase activity;1.00826983783411e-15!GO:0005746;mitochondrial respiratory chain;1.56771972374194e-15!GO:0000398;nuclear mRNA splicing, via spliceosome;1.66767930804533e-15!GO:0000375;RNA splicing, via transesterification reactions;1.66767930804533e-15!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.66767930804533e-15!GO:0009719;response to endogenous stimulus;3.27058597959242e-15!GO:0006260;DNA replication;3.58226126871715e-15!GO:0044248;cellular catabolic process;5.96301176632908e-15!GO:0051603;proteolysis involved in cellular protein catabolic process;7.26727198810698e-15!GO:0043412;biopolymer modification;7.66674560849062e-15!GO:0016568;chromatin modification;7.93805561370089e-15!GO:0019941;modification-dependent protein catabolic process;1.06892547582629e-14!GO:0043632;modification-dependent macromolecule catabolic process;1.06892547582629e-14!GO:0006511;ubiquitin-dependent protein catabolic process;1.19623618710231e-14!GO:0044257;cellular protein catabolic process;1.56939072378391e-14!GO:0008135;translation factor activity, nucleic acid binding;1.61649089133011e-14!GO:0008026;ATP-dependent helicase activity;1.72361691937463e-14!GO:0050136;NADH dehydrogenase (quinone) activity;4.73558966253298e-14!GO:0003954;NADH dehydrogenase activity;4.73558966253298e-14!GO:0008137;NADH dehydrogenase (ubiquinone) activity;4.73558966253298e-14!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;5.09483554530834e-14!GO:0000087;M phase of mitotic cell cycle;8.2611739388193e-14!GO:0016607;nuclear speck;1.70188847439136e-13!GO:0007067;mitosis;1.95704022523674e-13!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);2.16348700809549e-13!GO:0051082;unfolded protein binding;2.31109394110237e-13!GO:0006605;protein targeting;2.38222147868077e-13!GO:0005635;nuclear envelope;2.4040289892442e-13!GO:0019222;regulation of metabolic process;3.19907104115106e-13!GO:0051301;cell division;3.78210849927503e-13!GO:0050657;nucleic acid transport;4.25023664307263e-13!GO:0051236;establishment of RNA localization;4.25023664307263e-13!GO:0050658;RNA transport;4.25023664307263e-13!GO:0006403;RNA localization;4.32104599634174e-13!GO:0051186;cofactor metabolic process;4.37532039348038e-13!GO:0050794;regulation of cellular process;4.52277526374409e-13!GO:0005761;mitochondrial ribosome;7.37376816129374e-13!GO:0000313;organellar ribosome;7.37376816129374e-13!GO:0000502;proteasome complex (sensu Eukaryota);8.96766512796417e-13!GO:0048770;pigment granule;1.18338644819418e-12!GO:0042470;melanosome;1.18338644819418e-12!GO:0044453;nuclear membrane part;1.32903073093999e-12!GO:0006464;protein modification process;1.35352970431832e-12!GO:0006333;chromatin assembly or disassembly;1.4995392274519e-12!GO:0000279;M phase;1.58380469005361e-12!GO:0031965;nuclear membrane;2.48145265036858e-12!GO:0042775;organelle ATP synthesis coupled electron transport;3.62824013824368e-12!GO:0042773;ATP synthesis coupled electron transport;3.62824013824368e-12!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);4.19330628808815e-12!GO:0006364;rRNA processing;4.39021337225177e-12!GO:0030964;NADH dehydrogenase complex (quinone);5.82481353784421e-12!GO:0045271;respiratory chain complex I;5.82481353784421e-12!GO:0005747;mitochondrial respiratory chain complex I;5.82481353784421e-12!GO:0030163;protein catabolic process;5.91590997222275e-12!GO:0000785;chromatin;7.87903138838111e-12!GO:0016072;rRNA metabolic process;1.08737533828179e-11!GO:0005643;nuclear pore;1.09107333828284e-11!GO:0065004;protein-DNA complex assembly;1.42917978498224e-11!GO:0006413;translational initiation;1.73367778555727e-11!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.95813420192213e-11!GO:0051028;mRNA transport;2.18972559278274e-11!GO:0006350;transcription;2.43951577417949e-11!GO:0031323;regulation of cellular metabolic process;3.11120200886151e-11!GO:0006399;tRNA metabolic process;4.28864248035679e-11!GO:0006913;nucleocytoplasmic transport;5.96947519172687e-11!GO:0003743;translation initiation factor activity;6.88426036140877e-11!GO:0006446;regulation of translational initiation;7.24647174377976e-11!GO:0051726;regulation of cell cycle;7.93351542845199e-11!GO:0003712;transcription cofactor activity;9.96566214176526e-11!GO:0000074;regulation of progression through cell cycle;1.19455645101889e-10!GO:0043687;post-translational protein modification;1.19507002925721e-10!GO:0051169;nuclear transport;1.23918519306192e-10!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.7887871883388e-10!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;2.08154863443955e-10!GO:0048193;Golgi vesicle transport;2.13460161914349e-10!GO:0046930;pore complex;3.18498179614785e-10!GO:0050789;regulation of biological process;5.30174480525853e-10!GO:0010468;regulation of gene expression;7.49083101259631e-10!GO:0005783;endoplasmic reticulum;9.57569871359417e-10!GO:0006732;coenzyme metabolic process;9.57569871359417e-10!GO:0012501;programmed cell death;1.08251391599473e-09!GO:0065002;intracellular protein transport across a membrane;1.3403532992702e-09!GO:0006915;apoptosis;1.55071045856538e-09!GO:0044432;endoplasmic reticulum part;2.76184648871503e-09!GO:0016192;vesicle-mediated transport;2.9742588619105e-09!GO:0043566;structure-specific DNA binding;4.222111213827e-09!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;4.39747162006481e-09!GO:0004812;aminoacyl-tRNA ligase activity;4.39747162006481e-09!GO:0016875;ligase activity, forming carbon-oxygen bonds;4.39747162006481e-09!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;5.22381786818604e-09!GO:0008219;cell death;5.29811631074136e-09!GO:0016265;death;5.29811631074136e-09!GO:0006366;transcription from RNA polymerase II promoter;5.51376137388374e-09!GO:0008639;small protein conjugating enzyme activity;5.51376137388374e-09!GO:0032774;RNA biosynthetic process;5.62958986758169e-09!GO:0005794;Golgi apparatus;5.72825076280808e-09!GO:0003697;single-stranded DNA binding;6.72508555475557e-09!GO:0006351;transcription, DNA-dependent;6.98141994373269e-09!GO:0030532;small nuclear ribonucleoprotein complex;9.51333572464558e-09!GO:0016740;transferase activity;9.86227353129673e-09!GO:0043038;amino acid activation;1.32573665584009e-08!GO:0006418;tRNA aminoacylation for protein translation;1.32573665584009e-08!GO:0043039;tRNA aminoacylation;1.32573665584009e-08!GO:0004842;ubiquitin-protein ligase activity;1.41755918251904e-08!GO:0006461;protein complex assembly;1.41808528679973e-08!GO:0051188;cofactor biosynthetic process;1.4319403514102e-08!GO:0008565;protein transporter activity;1.58833395530426e-08!GO:0006164;purine nucleotide biosynthetic process;2.00093359899786e-08!GO:0017038;protein import;2.07095767787742e-08!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;2.14595172776218e-08!GO:0016779;nucleotidyltransferase activity;2.45195394825721e-08!GO:0006163;purine nucleotide metabolic process;2.79277021003531e-08!GO:0006334;nucleosome assembly;3.2630072732978e-08!GO:0031497;chromatin assembly;3.32024781183266e-08!GO:0000245;spliceosome assembly;4.75422231331644e-08!GO:0009056;catabolic process;5.80876913238358e-08!GO:0032446;protein modification by small protein conjugation;7.88865967744859e-08!GO:0009259;ribonucleotide metabolic process;8.267665937884e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;8.68038141145334e-08!GO:0019787;small conjugating protein ligase activity;9.02243551580452e-08!GO:0006261;DNA-dependent DNA replication;9.12863461664608e-08!GO:0003677;DNA binding;9.98482730308115e-08!GO:0009260;ribonucleotide biosynthetic process;1.15105347166286e-07!GO:0019829;cation-transporting ATPase activity;1.15313485017528e-07!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.198569207461e-07!GO:0000151;ubiquitin ligase complex;1.35345837138356e-07!GO:0016310;phosphorylation;1.51563799970266e-07!GO:0045449;regulation of transcription;1.65090473443229e-07!GO:0009152;purine ribonucleotide biosynthetic process;1.65090473443229e-07!GO:0015078;hydrogen ion transmembrane transporter activity;1.65401488574754e-07!GO:0051329;interphase of mitotic cell cycle;1.76505481560458e-07!GO:0003724;RNA helicase activity;1.83520081163807e-07!GO:0016567;protein ubiquitination;1.96829880677816e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.96988024943953e-07!GO:0006793;phosphorus metabolic process;2.07570230376113e-07!GO:0006796;phosphate metabolic process;2.07570230376113e-07!GO:0009150;purine ribonucleotide metabolic process;2.17747014050864e-07!GO:0016787;hydrolase activity;2.39830661821525e-07!GO:0009060;aerobic respiration;3.94867339215987e-07!GO:0005793;ER-Golgi intermediate compartment;4.12786666210982e-07!GO:0015986;ATP synthesis coupled proton transport;4.22493748484295e-07!GO:0015985;energy coupled proton transport, down electrochemical gradient;4.22493748484295e-07!GO:0009142;nucleoside triphosphate biosynthetic process;4.51104412792436e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;4.51104412792436e-07!GO:0051325;interphase;5.32912304059619e-07!GO:0042175;nuclear envelope-endoplasmic reticulum network;6.62344652969029e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;9.49263014549116e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;9.49263014549116e-07!GO:0045259;proton-transporting ATP synthase complex;1.03751451355308e-06!GO:0016881;acid-amino acid ligase activity;1.18961071937816e-06!GO:0065007;biological regulation;1.21581575260992e-06!GO:0003729;mRNA binding;1.40090031473798e-06!GO:0009199;ribonucleoside triphosphate metabolic process;1.41177046297256e-06!GO:0005789;endoplasmic reticulum membrane;1.42552796117699e-06!GO:0009141;nucleoside triphosphate metabolic process;1.42552796117699e-06!GO:0006754;ATP biosynthetic process;1.94185366189424e-06!GO:0006753;nucleoside phosphate metabolic process;1.94185366189424e-06!GO:0006355;regulation of transcription, DNA-dependent;2.31627949995562e-06!GO:0008270;zinc ion binding;2.38694445292106e-06!GO:0009055;electron carrier activity;2.51881677693816e-06!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.73348210053095e-06!GO:0009144;purine nucleoside triphosphate metabolic process;2.73348210053095e-06!GO:0000775;chromosome, pericentric region;2.84786725336e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;2.87795850382686e-06!GO:0009108;coenzyme biosynthetic process;3.20970711233128e-06!GO:0000075;cell cycle checkpoint;3.20970711233128e-06!GO:0015630;microtubule cytoskeleton;4.12679538921227e-06!GO:0003713;transcription coactivator activity;4.61350074692665e-06!GO:0003899;DNA-directed RNA polymerase activity;4.90249290434553e-06!GO:0003682;chromatin binding;5.04447008618602e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;5.86947823242723e-06!GO:0006752;group transfer coenzyme metabolic process;5.97698599489228e-06!GO:0051246;regulation of protein metabolic process;6.17905312069195e-06!GO:0044452;nucleolar part;6.64113369890212e-06!GO:0042981;regulation of apoptosis;6.74195164374389e-06!GO:0005813;centrosome;6.94728322576773e-06!GO:0043067;regulation of programmed cell death;6.98224394771412e-06!GO:0016469;proton-transporting two-sector ATPase complex;6.98224394771412e-06!GO:0006888;ER to Golgi vesicle-mediated transport;7.75519568114032e-06!GO:0046034;ATP metabolic process;8.13561230122875e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;9.71924382094073e-06!GO:0046914;transition metal ion binding;1.02266457702117e-05!GO:0007051;spindle organization and biogenesis;1.05807148881925e-05!GO:0045333;cellular respiration;1.07032687727349e-05!GO:0048475;coated membrane;1.10946151401318e-05!GO:0030117;membrane coat;1.10946151401318e-05!GO:0005768;endosome;1.12024010020595e-05!GO:0006402;mRNA catabolic process;1.13246874699153e-05!GO:0051168;nuclear export;1.13853440721198e-05!GO:0005667;transcription factor complex;1.24856470803317e-05!GO:0008186;RNA-dependent ATPase activity;1.25586768534925e-05!GO:0008094;DNA-dependent ATPase activity;1.48193566651607e-05!GO:0005815;microtubule organizing center;1.63244840170017e-05!GO:0006401;RNA catabolic process;1.63244840170017e-05!GO:0005819;spindle;1.68969649027946e-05!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.83669091835644e-05!GO:0006302;double-strand break repair;2.05174203845992e-05!GO:0006606;protein import into nucleus;2.10942885959937e-05!GO:0007005;mitochondrion organization and biogenesis;2.30193352483484e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;2.4294156880865e-05!GO:0015399;primary active transmembrane transporter activity;2.4294156880865e-05!GO:0051170;nuclear import;2.61436682366253e-05!GO:0006310;DNA recombination;2.73675274749548e-05!GO:0005657;replication fork;3.06046507608413e-05!GO:0003690;double-stranded DNA binding;3.10525790015142e-05!GO:0016741;transferase activity, transferring one-carbon groups;3.6771024823745e-05!GO:0004004;ATP-dependent RNA helicase activity;4.23752566134374e-05!GO:0006084;acetyl-CoA metabolic process;4.55179249495423e-05!GO:0005839;proteasome core complex (sensu Eukaryota);4.65493088539292e-05!GO:0030120;vesicle coat;4.87680054745317e-05!GO:0030662;coated vesicle membrane;4.87680054745317e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;5.0462935832602e-05!GO:0008168;methyltransferase activity;5.15637839227413e-05!GO:0006383;transcription from RNA polymerase III promoter;5.27560191369498e-05!GO:0006099;tricarboxylic acid cycle;5.48767961360867e-05!GO:0046356;acetyl-CoA catabolic process;5.48767961360867e-05!GO:0006613;cotranslational protein targeting to membrane;5.67236170847146e-05!GO:0043492;ATPase activity, coupled to movement of substances;6.07681994025214e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;7.39492667969157e-05!GO:0003714;transcription corepressor activity;8.46057408501674e-05!GO:0005762;mitochondrial large ribosomal subunit;8.64167337676186e-05!GO:0000315;organellar large ribosomal subunit;8.64167337676186e-05!GO:0016363;nuclear matrix;8.94145433003592e-05!GO:0043623;cellular protein complex assembly;9.23851949703663e-05!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;9.69163296686559e-05!GO:0048471;perinuclear region of cytoplasm;0.000102293136092568!GO:0031072;heat shock protein binding;0.000107138352831397!GO:0003678;DNA helicase activity;0.000113962125712616!GO:0009117;nucleotide metabolic process;0.000120342872083465!GO:0048523;negative regulation of cellular process;0.000132356400214301!GO:0045786;negative regulation of progression through cell cycle;0.000141834750932353!GO:0016563;transcription activator activity;0.000141834750932353!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000144450567078275!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.00016158162450239!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000204164581743425!GO:0003684;damaged DNA binding;0.000210285720365749!GO:0016859;cis-trans isomerase activity;0.000212618728727609!GO:0005770;late endosome;0.000212618728727609!GO:0006405;RNA export from nucleus;0.000215790689321504!GO:0004527;exonuclease activity;0.000218430637636906!GO:0000786;nucleosome;0.000227600044445382!GO:0000314;organellar small ribosomal subunit;0.000231086587560754!GO:0005763;mitochondrial small ribosomal subunit;0.000231086587560754!GO:0051187;cofactor catabolic process;0.000240299087040846!GO:0006091;generation of precursor metabolites and energy;0.000247694179545726!GO:0004298;threonine endopeptidase activity;0.000247694179545726!GO:0016853;isomerase activity;0.000267133975535868!GO:0043414;biopolymer methylation;0.000274522588280061!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.000275017495247092!GO:0043021;ribonucleoprotein binding;0.000275373798019591!GO:0009109;coenzyme catabolic process;0.000276171847175851!GO:0005788;endoplasmic reticulum lumen;0.000293836443480969!GO:0016491;oxidoreductase activity;0.000294499994226143!GO:0006612;protein targeting to membrane;0.000307909870151357!GO:0008276;protein methyltransferase activity;0.000311262970468602!GO:0006338;chromatin remodeling;0.000312729251707296!GO:0051427;hormone receptor binding;0.000329125947929244!GO:0044431;Golgi apparatus part;0.000330803085480148!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000359838561479334!GO:0044440;endosomal part;0.000441173032924858!GO:0010008;endosome membrane;0.000441173032924858!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000454791970717404!GO:0006352;transcription initiation;0.000455050594314724!GO:0006082;organic acid metabolic process;0.000459336626829435!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.000459336626829435!GO:0019752;carboxylic acid metabolic process;0.000465744193230308!GO:0019899;enzyme binding;0.000471890928105771!GO:0000776;kinetochore;0.000481417946218233!GO:0006950;response to stress;0.000484338971347226!GO:0031324;negative regulation of cellular metabolic process;0.000514462393555766!GO:0008654;phospholipid biosynthetic process;0.00055351288682!GO:0008033;tRNA processing;0.00056088120769696!GO:0035257;nuclear hormone receptor binding;0.000632491256234272!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.000632491256234272!GO:0007088;regulation of mitosis;0.000658336695032229!GO:0022890;inorganic cation transmembrane transporter activity;0.000696530241733625!GO:0003924;GTPase activity;0.000737135539129205!GO:0043069;negative regulation of programmed cell death;0.00076804679161967!GO:0005885;Arp2/3 protein complex;0.000853308175773697!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.000905979142357818!GO:0045045;secretory pathway;0.000935219326624273!GO:0047485;protein N-terminus binding;0.000949379402031721!GO:0004674;protein serine/threonine kinase activity;0.00100679970319189!GO:0043066;negative regulation of apoptosis;0.00101252731188872!GO:0007052;mitotic spindle organization and biogenesis;0.00102525930582643!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00103122606150824!GO:0043681;protein import into mitochondrion;0.00105145280522728!GO:0007093;mitotic cell cycle checkpoint;0.00105777531391443!GO:0048519;negative regulation of biological process;0.00107441903043689!GO:0045454;cell redox homeostasis;0.00108199255836408!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00113771322677666!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00116194096857527!GO:0016564;transcription repressor activity;0.00121703723140044!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0012495311342233!GO:0030880;RNA polymerase complex;0.00132158739185974!GO:0000049;tRNA binding;0.00132968517931635!GO:0000792;heterochromatin;0.00137645519822636!GO:0046483;heterocycle metabolic process;0.00141811020133798!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00144371542163719!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00144371542163719!GO:0030867;rough endoplasmic reticulum membrane;0.00144788455589087!GO:0005769;early endosome;0.00148490602442898!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00149351809534588!GO:0000059;protein import into nucleus, docking;0.00153602991072323!GO:0042802;identical protein binding;0.00154485344736811!GO:0007243;protein kinase cascade;0.00154485344736811!GO:0032259;methylation;0.00157149475556751!GO:0031252;leading edge;0.00164613977970583!GO:0004518;nuclease activity;0.00170161798452023!GO:0032508;DNA duplex unwinding;0.00178394056349375!GO:0032392;DNA geometric change;0.00178394056349375!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00189417146146451!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00189417146146451!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00189417146146451!GO:0051052;regulation of DNA metabolic process;0.00189417146146451!GO:0000082;G1/S transition of mitotic cell cycle;0.00192744280152164!GO:0009165;nucleotide biosynthetic process;0.00194273616717084!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00199212878978367!GO:0006626;protein targeting to mitochondrion;0.00201512926203709!GO:0006730;one-carbon compound metabolic process;0.00202479436888324!GO:0000139;Golgi membrane;0.00209802313815148!GO:0016272;prefoldin complex;0.00229715395988945!GO:0006268;DNA unwinding during replication;0.00263867381161599!GO:0015992;proton transport;0.00297461835680768!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00301765668530177!GO:0000428;DNA-directed RNA polymerase complex;0.00301765668530177!GO:0006916;anti-apoptosis;0.00307537738481426!GO:0006520;amino acid metabolic process;0.00317807926010762!GO:0040029;regulation of gene expression, epigenetic;0.00323522274782844!GO:0005048;signal sequence binding;0.00348337742137534!GO:0006818;hydrogen transport;0.00352034298373476!GO:0016481;negative regulation of transcription;0.00352955618368806!GO:0032984;macromolecular complex disassembly;0.00358173932228583!GO:0048500;signal recognition particle;0.00366000680707737!GO:0009081;branched chain family amino acid metabolic process;0.00386176912872673!GO:0005684;U2-dependent spliceosome;0.00388061601703336!GO:0005798;Golgi-associated vesicle;0.00396276153075882!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00398960776080692!GO:0015002;heme-copper terminal oxidase activity;0.00398960776080692!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00398960776080692!GO:0004129;cytochrome-c oxidase activity;0.00398960776080692!GO:0007006;mitochondrial membrane organization and biogenesis;0.00416178810303923!GO:0005525;GTP binding;0.00417016331669237!GO:0042393;histone binding;0.00424824483809186!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00440321877515384!GO:0043241;protein complex disassembly;0.00453419668238929!GO:0042054;histone methyltransferase activity;0.00453735527042847!GO:0003711;transcription elongation regulator activity;0.00476857936531638!GO:0009892;negative regulation of metabolic process;0.00481518470959071!GO:0015980;energy derivation by oxidation of organic compounds;0.00485370417277616!GO:0005876;spindle microtubule;0.00493212738079086!GO:0015036;disulfide oxidoreductase activity;0.00510977502878608!GO:0006778;porphyrin metabolic process;0.00516885977954791!GO:0033013;tetrapyrrole metabolic process;0.00516885977954791!GO:0006406;mRNA export from nucleus;0.00540210163147798!GO:0032940;secretion by cell;0.00540337308094945!GO:0035258;steroid hormone receptor binding;0.00542213027809334!GO:0006284;base-excision repair;0.00554918829145386!GO:0031988;membrane-bound vesicle;0.00569208997538339!GO:0051920;peroxiredoxin activity;0.00571016376184739!GO:0016584;nucleosome positioning;0.00571690660715005!GO:0006417;regulation of translation;0.00583147313797047!GO:0006414;translational elongation;0.00583790128626831!GO:0006779;porphyrin biosynthetic process;0.00596176688527601!GO:0033014;tetrapyrrole biosynthetic process;0.00596176688527601!GO:0006270;DNA replication initiation;0.0061123452693949!GO:0008047;enzyme activator activity;0.00618612162374743!GO:0046588;negative regulation of calcium-dependent cell-cell adhesion;0.00624960043188873!GO:0046586;regulation of calcium-dependent cell-cell adhesion;0.00624960043188873!GO:0051252;regulation of RNA metabolic process;0.00639201042772858!GO:0005669;transcription factor TFIID complex;0.00651265333030257!GO:0031968;organelle outer membrane;0.00665333025553053!GO:0019867;outer membrane;0.00668221581013729!GO:0005741;mitochondrial outer membrane;0.00673298397786325!GO:0008234;cysteine-type peptidase activity;0.00674417543243418!GO:0015631;tubulin binding;0.00684632939918162!GO:0000096;sulfur amino acid metabolic process;0.00702280336240351!GO:0006839;mitochondrial transport;0.00756124496697649!GO:0032287;myelin maintenance in the peripheral nervous system;0.00756124496697649!GO:0032838;cell projection cytoplasm;0.00756124496697649!GO:0033081;regulation of T cell differentiation in the thymus;0.00756124496697649!GO:0043217;myelin maintenance;0.00756124496697649!GO:0060087;relaxation of vascular smooth muscle;0.00756124496697649!GO:0032839;dendrite cytoplasm;0.00756124496697649!GO:0030118;clathrin coat;0.00829031442294345!GO:0000228;nuclear chromosome;0.00834745548086448!GO:0046474;glycerophospholipid biosynthetic process;0.00841416036219053!GO:0000725;recombinational repair;0.00845512020100783!GO:0000724;double-strand break repair via homologous recombination;0.00845512020100783!GO:0051087;chaperone binding;0.00871485759602565!GO:0043624;cellular protein complex disassembly;0.008902658498812!GO:0032200;telomere organization and biogenesis;0.00897547049399994!GO:0000723;telomere maintenance;0.00897547049399994!GO:0007017;microtubule-based process;0.00908719860325386!GO:0016251;general RNA polymerase II transcription factor activity;0.00935237463680995!GO:0004003;ATP-dependent DNA helicase activity;0.00943249606245632!GO:0022406;membrane docking;0.00950750867889522!GO:0048278;vesicle docking;0.00950750867889522!GO:0016605;PML body;0.00963412843548346!GO:0031982;vesicle;0.00978560451776962!GO:0008610;lipid biosynthetic process;0.010415348038669!GO:0007059;chromosome segregation;0.010465039462882!GO:0016023;cytoplasmic membrane-bound vesicle;0.0106147948311488!GO:0018193;peptidyl-amino acid modification;0.0109654817180036!GO:0000790;nuclear chromatin;0.0110002521015158!GO:0044454;nuclear chromosome part;0.0110222478948016!GO:0005096;GTPase activator activity;0.0112422421764897!GO:0065009;regulation of a molecular function;0.0112654028339679!GO:0006611;protein export from nucleus;0.0113034499564382!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0113533399873077!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0115999766059879!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0116081359966261!GO:0045047;protein targeting to ER;0.0116081359966261!GO:0006595;polyamine metabolic process;0.0117240053440499!GO:0031124;mRNA 3'-end processing;0.0117478180822927!GO:0042168;heme metabolic process;0.0118246682532621!GO:0030134;ER to Golgi transport vesicle;0.0119272077962553!GO:0000922;spindle pole;0.0123737280392765!GO:0043596;nuclear replication fork;0.0125168852548116!GO:0005874;microtubule;0.0129416490208468!GO:0008213;protein amino acid alkylation;0.0130469546871656!GO:0006479;protein amino acid methylation;0.0130469546871656!GO:0016279;protein-lysine N-methyltransferase activity;0.0130883798669858!GO:0018024;histone-lysine N-methyltransferase activity;0.0130883798669858!GO:0016278;lysine N-methyltransferase activity;0.0130883798669858!GO:0030384;phosphoinositide metabolic process;0.0131186117649851!GO:0006783;heme biosynthetic process;0.0135021516776424!GO:0008017;microtubule binding;0.0135021516776424!GO:0046467;membrane lipid biosynthetic process;0.0136180013680588!GO:0005637;nuclear inner membrane;0.0136478573350719!GO:0007021;tubulin folding;0.01372024119559!GO:0043488;regulation of mRNA stability;0.01372024119559!GO:0043487;regulation of RNA stability;0.01372024119559!GO:0005791;rough endoplasmic reticulum;0.0138409907332406!GO:0008139;nuclear localization sequence binding;0.0139759220998162!GO:0051789;response to protein stimulus;0.0142911185196608!GO:0006986;response to unfolded protein;0.0142911185196608!GO:0019843;rRNA binding;0.0151315413290304!GO:0000152;nuclear ubiquitin ligase complex;0.0154342981606326!GO:0005665;DNA-directed RNA polymerase II, core complex;0.015536489903329!GO:0006376;mRNA splice site selection;0.01580499003913!GO:0000389;nuclear mRNA 3'-splice site recognition;0.01580499003913!GO:0050178;phenylpyruvate tautomerase activity;0.0160470089692165!GO:0004177;aminopeptidase activity;0.0160910316378752!GO:0006904;vesicle docking during exocytosis;0.0161831335860102!GO:0043284;biopolymer biosynthetic process;0.0165788881998183!GO:0045815;positive regulation of gene expression, epigenetic;0.0169124130809217!GO:0032561;guanyl ribonucleotide binding;0.0173414772908127!GO:0019001;guanyl nucleotide binding;0.0173414772908127!GO:0033116;ER-Golgi intermediate compartment membrane;0.0175246301469482!GO:0005758;mitochondrial intermembrane space;0.0175250879423402!GO:0051540;metal cluster binding;0.0177059494973808!GO:0051536;iron-sulfur cluster binding;0.0177059494973808!GO:0051053;negative regulation of DNA metabolic process;0.0177221632834494!GO:0043189;H4/H2A histone acetyltransferase complex;0.0180043656344019!GO:0005938;cell cortex;0.0184212087069075!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0184996452740397!GO:0008312;7S RNA binding;0.0186059595481901!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0186732285778868!GO:0005773;vacuole;0.0186851828455494!GO:0022411;cellular component disassembly;0.0187562536654935!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0193997405303188!GO:0044262;cellular carbohydrate metabolic process;0.019758437011255!GO:0016197;endosome transport;0.0198940319469057!GO:0042158;lipoprotein biosynthetic process;0.0201049451396701!GO:0030658;transport vesicle membrane;0.0201301822483813!GO:0031410;cytoplasmic vesicle;0.0206400533485464!GO:0044448;cell cortex part;0.0207612532876727!GO:0000339;RNA cap binding;0.0208485819414862!GO:0030663;COPI coated vesicle membrane;0.0208485819414862!GO:0030126;COPI vesicle coat;0.0208485819414862!GO:0007050;cell cycle arrest;0.0209135341360238!GO:0035267;NuA4 histone acetyltransferase complex;0.0209437197178529!GO:0006289;nucleotide-excision repair;0.0209511348978883!GO:0016569;covalent chromatin modification;0.0209512866049499!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.0211993826155837!GO:0042770;DNA damage response, signal transduction;0.0213430621015542!GO:0006497;protein amino acid lipidation;0.0214560482902849!GO:0000287;magnesium ion binding;0.0215520614245253!GO:0005720;nuclear heterochromatin;0.0216603682526344!GO:0031326;regulation of cellular biosynthetic process;0.0218945185241549!GO:0009083;branched chain family amino acid catabolic process;0.0220249401179765!GO:0005487;nucleocytoplasmic transporter activity;0.0222422374657932!GO:0030132;clathrin coat of coated pit;0.0222489313499297!GO:0045892;negative regulation of transcription, DNA-dependent;0.0223337302982306!GO:0005832;chaperonin-containing T-complex;0.0223337302982306!GO:0008250;oligosaccharyl transferase complex;0.0224427845838486!GO:0008629;induction of apoptosis by intracellular signals;0.0225792340937477!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0227028169887645!GO:0006607;NLS-bearing substrate import into nucleus;0.0232425252940285!GO:0030119;AP-type membrane coat adaptor complex;0.0234982955879079!GO:0006308;DNA catabolic process;0.0234982955879079!GO:0030137;COPI-coated vesicle;0.0235040270283009!GO:0006378;mRNA polyadenylation;0.023580655114356!GO:0001726;ruffle;0.0238309486894323!GO:0006519;amino acid and derivative metabolic process;0.0239817953938032!GO:0030176;integral to endoplasmic reticulum membrane;0.0241024693685607!GO:0035035;histone acetyltransferase binding;0.0243766682277736!GO:0030521;androgen receptor signaling pathway;0.0246779530763724!GO:0000118;histone deacetylase complex;0.0249127153283516!GO:0051320;S phase;0.0251057676214195!GO:0006144;purine base metabolic process;0.0256203880200074!GO:0031570;DNA integrity checkpoint;0.0256204625866016!GO:0006917;induction of apoptosis;0.0263178682648463!GO:0006301;postreplication repair;0.0263191524184553!GO:0030127;COPII vesicle coat;0.0263221465572618!GO:0012507;ER to Golgi transport vesicle membrane;0.0263221465572618!GO:0009303;rRNA transcription;0.0270574599129435!GO:0008180;signalosome;0.0272566636706535!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0273463915973277!GO:0048487;beta-tubulin binding;0.0275694583505118!GO:0031902;late endosome membrane;0.0277159911437518!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0279469153948918!GO:0000123;histone acetyltransferase complex;0.0280529545587466!GO:0030911;TPR domain binding;0.028105580004032!GO:0031123;RNA 3'-end processing;0.0281360414871517!GO:0030218;erythrocyte differentiation;0.0282666316734083!GO:0009451;RNA modification;0.028750049283923!GO:0030131;clathrin adaptor complex;0.0289400331276767!GO:0008170;N-methyltransferase activity;0.0289934828891182!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0290688885928741!GO:0006650;glycerophospholipid metabolic process;0.0292505242944559!GO:0007265;Ras protein signal transduction;0.0293720163649909!GO:0002884;negative regulation of hypersensitivity;0.0299041913623521!GO:0002862;negative regulation of inflammatory response to antigenic stimulus;0.0299041913623521!GO:0045060;negative thymic T cell selection;0.0299041913623521!GO:0031254;trailing edge;0.0299041913623521!GO:0001807;regulation of type IV hypersensitivity;0.0299041913623521!GO:0001808;negative regulation of type IV hypersensitivity;0.0299041913623521!GO:0002674;negative regulation of acute inflammatory response;0.0299041913623521!GO:0002865;negative regulation of acute inflammatory response to antigenic stimulus;0.0299041913623521!GO:0043383;negative T cell selection;0.0299041913623521!GO:0001931;uropod;0.0299041913623521!GO:0001806;type IV hypersensitivity;0.0299041913623521!GO:0000178;exosome (RNase complex);0.0299496144072301!GO:0003725;double-stranded RNA binding;0.030080458250486!GO:0006007;glucose catabolic process;0.0302099053031125!GO:0008408;3'-5' exonuclease activity;0.0302099053031125!GO:0046489;phosphoinositide biosynthetic process;0.0302099053031125!GO:0005680;anaphase-promoting complex;0.0303750723696858!GO:0051059;NF-kappaB binding;0.0305036217716831!GO:0003857;3-hydroxyacyl-CoA dehydrogenase activity;0.0307278671339759!GO:0022415;viral reproductive process;0.0308972629316309!GO:0008632;apoptotic program;0.0310455102870092!GO:0031371;ubiquitin conjugating enzyme complex;0.0312591311963578!GO:0019783;small conjugating protein-specific protease activity;0.031491281201622!GO:0012502;induction of programmed cell death;0.031491281201622!GO:0051287;NAD binding;0.0314992637997497!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0315603920670376!GO:0002102;podosome;0.0325299714788055!GO:0006506;GPI anchor biosynthetic process;0.0328945712337105!GO:0004843;ubiquitin-specific protease activity;0.0329122873924711!GO:0004576;oligosaccharyl transferase activity;0.0329674615824065!GO:0006220;pyrimidine nucleotide metabolic process;0.033094592662229!GO:0031970;organelle envelope lumen;0.0336939850129625!GO:0042157;lipoprotein metabolic process;0.0340041684709741!GO:0031625;ubiquitin protein ligase binding;0.0340360348592487!GO:0004448;isocitrate dehydrogenase activity;0.0341444961466766!GO:0045947;negative regulation of translational initiation;0.0348688292084152!GO:0006493;protein amino acid O-linked glycosylation;0.0348802883174281!GO:0043601;nuclear replisome;0.0349579207429967!GO:0030894;replisome;0.0349579207429967!GO:0050662;coenzyme binding;0.0352201510530652!GO:0009112;nucleobase metabolic process;0.0352209854986213!GO:0016301;kinase activity;0.0352209854986213!GO:0000062;acyl-CoA binding;0.0352209854986213!GO:0006415;translational termination;0.0352209854986213!GO:0006275;regulation of DNA replication;0.0352209854986213!GO:0005652;nuclear lamina;0.0356642291799873!GO:0000781;chromosome, telomeric region;0.0356642291799873!GO:0030660;Golgi-associated vesicle membrane;0.0356970692320116!GO:0006118;electron transport;0.0363369564332534!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.0364817925071469!GO:0003756;protein disulfide isomerase activity;0.0364817925071469!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0364817925071469!GO:0000323;lytic vacuole;0.0370769412250617!GO:0005764;lysosome;0.0370769412250617!GO:0050681;androgen receptor binding;0.0377108287561354!GO:0043065;positive regulation of apoptosis;0.039307010967404!GO:0051101;regulation of DNA binding;0.0395241805539253!GO:0030518;steroid hormone receptor signaling pathway;0.0397305089820094!GO:0010149;senescence;0.0401613667098423!GO:0043022;ribosome binding;0.0403028492844037!GO:0043068;positive regulation of programmed cell death;0.0409823113550692!GO:0007346;regulation of progression through mitotic cell cycle;0.0410600934284769!GO:0006505;GPI anchor metabolic process;0.0410940266437719!GO:0004239;methionyl aminopeptidase activity;0.0413789741483663!GO:0000097;sulfur amino acid biosynthetic process;0.0423861640137126!GO:0006740;NADPH regeneration;0.0427154219791847!GO:0006098;pentose-phosphate shunt;0.0427154219791847!GO:0031577;spindle checkpoint;0.0427875431714371!GO:0016407;acetyltransferase activity;0.0428110882700464!GO:0008538;proteasome activator activity;0.0429289161688646!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0430658503435182!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0434727097797485!GO:0031461;cullin-RING ubiquitin ligase complex;0.043510611063916!GO:0050790;regulation of catalytic activity;0.0437941664145888!GO:0007259;JAK-STAT cascade;0.0444793313070759!GO:0016585;chromatin remodeling complex;0.044483738973283!GO:0000726;non-recombinational repair;0.0445254164693508!GO:0006555;methionine metabolic process;0.0446442482912789!GO:0008143;poly(A) binding;0.0447103400989811!GO:0000209;protein polyubiquitination;0.0449911231222003!GO:0043130;ubiquitin binding;0.0467183247157061!GO:0032182;small conjugating protein binding;0.0467183247157061!GO:0006635;fatty acid beta-oxidation;0.0470457544251499!GO:0018196;peptidyl-asparagine modification;0.0471578490265989!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0471578490265989!GO:0003887;DNA-directed DNA polymerase activity;0.047161643753354!GO:0003746;translation elongation factor activity;0.0472789043674834!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.0472789043674834!GO:0004300;enoyl-CoA hydratase activity;0.0481916189040826!GO:0001832;blastocyst growth;0.0486649103747479!GO:0006979;response to oxidative stress;0.0487302446002839!GO:0004532;exoribonuclease activity;0.0493445225411875!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0493445225411875!GO:0006266;DNA ligation;0.049935603558614!GO:0000803;sex chromosome;0.049935603558614!GO:0001739;sex chromatin;0.049935603558614!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0499389042820171 | |||
|sample_id=10802 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=GATA6:3.99464081648;STAT1,3:2.43359507398;RBPJ:2.2722451827;RXR{A,B,G}_{NR1H2,PPAR}dimers:2.05494509036;T:1.61937910875;MYB:1.5730864204;PPARG:1.51160908114;ALX1:1.48713406477;STAT5{A,B}:1.19553500726;BREu{core}:1.17481520585;NR5A1,2:1.15659219558;POU2F1..3:1.08934706438;YY1:1.06316679695;FOX{I1,J2}:1.03935642944;ELK1,4_GABP{A,B1}:1.03486547587;PITX1..3:0.972316687629;E2F1..5:0.968166950862;TOPORS:0.908598052599;RORA:0.897922233777;SPZ1:0.894880173607;CRX:0.894552142962;PAX3,7:0.878356724216;NFY{A,B,C}:0.875807248992;PBX1:0.868249229209;SOX{8,9,10}:0.862584518354;PRRX1,2:0.803627770661;NR6A1:0.791426827463;ELF1,2,4:0.757128972568;TFAP4:0.694698784452;ZNF143:0.678536369682;NRF1:0.647630052683;GCM1,2:0.647070445812;PAX6:0.644894906875;FOXN1:0.616205224066;SPIB:0.588830139777;PAX8:0.564608630925;ZNF148:0.560373946655;FOXP1:0.558747919727;DMAP1_NCOR{1,2}_SMARC:0.558697492786;HES1:0.524692659624;NKX2-1,4:0.510690383503;LEF1_TCF7_TCF7L1,2:0.506064042048;CUX2:0.501382844548;HOX{A4,D4}:0.478909077132;POU6F1:0.477672805683;NKX3-2:0.465366334536;NFIX:0.46064219562;HOX{A6,A7,B6,B7}:0.450628672748;SMAD1..7,9:0.364967414819;HAND1,2:0.350968530125;bHLH_family:0.329039052019;POU1F1:0.318984061759;OCT4_SOX2{dimer}:0.301602816295;RXRA_VDR{dimer}:0.291722248653;NR1H4:0.288101635544;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.275010030563;SPI1:0.271274622277;AHR_ARNT_ARNT2:0.268683940085;SOX17:0.261390452893;IKZF2:0.252103194247;AR:0.243040549704;RUNX1..3:0.2349658624;ETS1,2:0.232549241018;FOXA2:0.194397593525;TFDP1:0.194065826568;PAX2:0.185360985942;EVI1:0.145153826785;DBP:0.132967187901;CDX1,2,4:0.0848830546559;GFI1:0.0829934593006;POU3F1..4:0.0468623466056;FOXQ1:0.0305104174023;ADNP_IRX_SIX_ZHX:-0.0343676209786;RFX2..5_RFXANK_RFXAP:-0.0423572969759;IRF7:-0.0533616745872;ONECUT1,2:-0.0545816926257;ZBTB16:-0.0578194547777;SNAI1..3:-0.0663427448632;NHLH1,2:-0.0775150029218;SOX2:-0.0806592780716;XBP1:-0.0839484342796;NKX2-3_NKX2-5:-0.1031955386;TFAP2{A,C}:-0.117507379746;TGIF1:-0.128693901644;REST:-0.133444625698;IRF1,2:-0.13942340448;HNF1A:-0.145443404625;HNF4A_NR2F1,2:-0.165349701042;NFE2:-0.205485252792;MYOD1:-0.207600867905;STAT2,4,6:-0.220363778497;CDC5L:-0.235798928016;NANOG:-0.242098775967;EN1,2:-0.260721823162;HOXA9_MEIS1:-0.276452068087;HOX{A5,B5}:-0.280756484182;LHX3,4:-0.281472590387;NFKB1_REL_RELA:-0.295921864514;ATF5_CREB3:-0.315725988703;ZFP161:-0.320248372027;PAX5:-0.325277948682;SOX5:-0.330945792228;ZNF238:-0.348474286291;MEF2{A,B,C,D}:-0.373430687992;GLI1..3:-0.385503627958;SRF:-0.391548115508;TEF:-0.39944586447;NANOG{mouse}:-0.410913183328;MTE{core}:-0.415267114964;KLF4:-0.418074699315;POU5F1:-0.42350540073;SREBF1,2:-0.426442470139;TFAP2B:-0.455257562707;ZEB1:-0.464156760967;FOXP3:-0.486671718848;MYBL2:-0.5027215148;NFATC1..3:-0.508845362515;NKX6-1,2:-0.533909188494;FOS_FOS{B,L1}_JUN{B,D}:-0.540685743258;MED-1{core}:-0.552551737298;ESRRA:-0.553049464424;FOSL2:-0.55535442909;NFE2L2:-0.558212823663;BACH2:-0.562539946866;VSX1,2:-0.590602446425;HIC1:-0.621922670859;MTF1:-0.637168023747;GZF1:-0.660645468505;GTF2I:-0.668856062932;HMGA1,2:-0.682555929974;CEBPA,B_DDIT3:-0.685017176904;BPTF:-0.689727200374;NKX3-1:-0.69852609895;EGR1..3:-0.699287582279;RFX1:-0.709051951004;ZNF423:-0.719520109792;RREB1:-0.731432342279;NFIL3:-0.741457000969;CREB1:-0.741943216805;NR3C1:-0.781272941422;HLF:-0.793820853384;MYFfamily:-0.804796061117;ARID5B:-0.817595553219;PDX1:-0.829370103234;FOXD3:-0.837734872402;NFE2L1:-0.848489309287;EBF1:-0.853197224268;IKZF1:-0.856028066977;NKX2-2,8:-0.859809756973;HMX1:-0.868747266902;FOX{D1,D2}:-0.885922231638;GTF2A1,2:-0.891235927663;MZF1:-0.899940909568;RXR{A,B,G}:-0.902596823366;FOX{F1,F2,J1}:-0.92657502812;TLX1..3_NFIC{dimer}:-0.932870850908;PATZ1:-0.965317447723;TEAD1:-1.00089488453;GFI1B:-1.01674949385;TAL1_TCF{3,4,12}:-1.02653811605;TP53:-1.03553688145;ATF4:-1.03944597807;ESR1:-1.04977505187;ATF6:-1.05549084688;TLX2:-1.05694153346;ZNF384:-1.07454603889;FOXL1:-1.08442265159;PAX1,9:-1.09138783708;PAX4:-1.10815681264;ZBTB6:-1.12591166731;AIRE:-1.18858199217;UFEwm:-1.19905655561;ATF2:-1.21331240614;LMO2:-1.2212267712;MAFB:-1.22437657002;FOXO1,3,4:-1.22821038708;EP300:-1.24971127452;MAZ:-1.28508200978;SP1:-1.3041641858;PRDM1:-1.31359675284;XCPE1{core}:-1.38838732009;HIF1A:-1.3943317507;HSF1,2:-1.4120288609;GATA4:-1.42267385334;FOXM1:-1.43190825938;JUN:-1.60379138292;TBP:-1.64023874352;TFCP2:-1.64222132954;ZIC1..3:-1.671802313;TBX4,5:-1.78721662331;HBP1_HMGB_SSRP1_UBTF:-1.83598348501;ALX4:-2.39148627106 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10802-111A1;search_select_hide=table117:FF:10802-111A1 | |||
}} | }} |
Latest revision as of 15:05, 3 June 2020
Name: | acute myeloid leukemia (FAB M7) cell line:MKPL-1 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11888 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11888
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11888
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0102 |
10 | 10 | 0.0462 |
100 | 100 | 0.618 |
101 | 101 | 0.416 |
102 | 102 | 0.34 |
103 | 103 | 0.381 |
104 | 104 | 0.847 |
105 | 105 | 0.341 |
106 | 106 | 0.335 |
107 | 107 | 0.465 |
108 | 108 | 0.744 |
109 | 109 | 0.0389 |
11 | 11 | 0.097 |
110 | 110 | 0.541 |
111 | 111 | 0.00271 |
112 | 112 | 0.322 |
113 | 113 | 0.394 |
114 | 114 | 0.0456 |
115 | 115 | 0.073 |
116 | 116 | 0.149 |
117 | 117 | 0.0651 |
118 | 118 | 0.697 |
119 | 119 | 0.282 |
12 | 12 | 0.414 |
120 | 120 | 0.788 |
121 | 121 | 0.484 |
122 | 122 | 0.358 |
123 | 123 | 1.2231e-4 |
124 | 124 | 0.0163 |
125 | 125 | 0.812 |
126 | 126 | 0.322 |
127 | 127 | 0.288 |
128 | 128 | 0.392 |
129 | 129 | 0.186 |
13 | 13 | 0.0216 |
130 | 130 | 0.447 |
131 | 131 | 0.604 |
132 | 132 | 0.121 |
133 | 133 | 0.641 |
134 | 134 | 0.579 |
135 | 135 | 0.467 |
136 | 136 | 0.164 |
137 | 137 | 0.648 |
138 | 138 | 0.908 |
139 | 139 | 0.36 |
14 | 14 | 0.638 |
140 | 140 | 0.9 |
141 | 141 | 0.274 |
142 | 142 | 0.44 |
143 | 143 | 0.781 |
144 | 144 | 0.947 |
145 | 145 | 0.515 |
146 | 146 | 0.69 |
147 | 147 | 0.0562 |
148 | 148 | 0.572 |
149 | 149 | 0.266 |
15 | 15 | 0.125 |
150 | 150 | 0.827 |
151 | 151 | 0.732 |
152 | 152 | 0.102 |
153 | 153 | 0.727 |
154 | 154 | 0.659 |
155 | 155 | 0.241 |
156 | 156 | 0.365 |
157 | 157 | 0.705 |
158 | 158 | 0.187 |
159 | 159 | 0.682 |
16 | 16 | 0.639 |
160 | 160 | 0.588 |
161 | 161 | 0.133 |
162 | 162 | 0.587 |
163 | 163 | 0.157 |
164 | 164 | 0.972 |
165 | 165 | 0.526 |
166 | 166 | 0.227 |
167 | 167 | 0.195 |
168 | 168 | 0.868 |
169 | 169 | 0.75 |
17 | 17 | 0.928 |
18 | 18 | 0.483 |
19 | 19 | 0.576 |
2 | 2 | 0.628 |
20 | 20 | 0.766 |
21 | 21 | 0.788 |
22 | 22 | 0.63 |
23 | 23 | 0.102 |
24 | 24 | 0.699 |
25 | 25 | 0.185 |
26 | 26 | 0.473 |
27 | 27 | 0.614 |
28 | 28 | 0.818 |
29 | 29 | 0.259 |
3 | 3 | 0.435 |
30 | 30 | 0.118 |
31 | 31 | 0.35 |
32 | 32 | 0.028 |
33 | 33 | 0.634 |
34 | 34 | 0.949 |
35 | 35 | 0.142 |
36 | 36 | 0.014 |
37 | 37 | 0.58 |
38 | 38 | 0.493 |
39 | 39 | 0.328 |
4 | 4 | 0.0848 |
40 | 40 | 0.139 |
41 | 41 | 0.79 |
42 | 42 | 0.275 |
43 | 43 | 0.86 |
44 | 44 | 0.722 |
45 | 45 | 0.809 |
46 | 46 | 0.263 |
47 | 47 | 0.116 |
48 | 48 | 0.139 |
49 | 49 | 0.0694 |
5 | 5 | 0.632 |
50 | 50 | 0.861 |
51 | 51 | 0.461 |
52 | 52 | 0.918 |
53 | 53 | 0.104 |
54 | 54 | 0.778 |
55 | 55 | 0.391 |
56 | 56 | 0.564 |
57 | 57 | 0.126 |
58 | 58 | 0.0706 |
59 | 59 | 0.983 |
6 | 6 | 0.372 |
60 | 60 | 0.711 |
61 | 61 | 0.291 |
62 | 62 | 0.0959 |
63 | 63 | 0.962 |
64 | 64 | 0.0685 |
65 | 65 | 0.942 |
66 | 66 | 0.0385 |
67 | 67 | 0.759 |
68 | 68 | 0.201 |
69 | 69 | 0.605 |
7 | 7 | 0.161 |
70 | 70 | 0.807 |
71 | 71 | 0.48 |
72 | 72 | 0.826 |
73 | 73 | 0.546 |
74 | 74 | 0.779 |
75 | 75 | 0.152 |
76 | 76 | 0.404 |
77 | 77 | 0.42 |
78 | 78 | 0.00318 |
79 | 79 | 0.154 |
8 | 8 | 0.38 |
80 | 80 | 0.884 |
81 | 81 | 0.562 |
82 | 82 | 0.487 |
83 | 83 | 0.493 |
84 | 84 | 0.935 |
85 | 85 | 0.377 |
86 | 86 | 0.877 |
87 | 87 | 0.306 |
88 | 88 | 0.756 |
89 | 89 | 0.868 |
9 | 9 | 0.806 |
90 | 90 | 0.273 |
91 | 91 | 0.411 |
92 | 92 | 0.337 |
93 | 93 | 0.979 |
94 | 94 | 0.709 |
95 | 95 | 0.175 |
96 | 96 | 0.0661 |
97 | 97 | 0.663 |
98 | 98 | 0.114 |
99 | 99 | 0.155 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11888
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0101883 acute myeloid leukemia cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
1240 (leukemia)
8692 (myeloid leukemia)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100737 (leukemia cell line sample)
0101035 (hematopoietic cell line sample)
0101883 (acute myeloid leukemia cell line sample)
0100740 (myeloid leukemia cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)