FF:11864-125B1: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005955 | ||
| | |accession_numbers=CAGE;DRX008147;DRR009019;DRZ000444;DRZ001829;DRZ011794;DRZ013179 | ||
| | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000766,CL:0000219,CL:0000325,CL:0000473,CL:0000234,CL:0000738,CL:0002087,CL:0000255,CL:0000576,CL:0000860,CL:0002057 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001,FF:0000625,FF:0000350,FF:0000632,FF:0011106 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr2:68592406..68592424,+!p1@PLEK!3.42!2604.47!PLEK;;chr11:47400078..47400106,-!p1@SPI1!2.85!700.63!SPI1;;chr12:72056800..72056834,+!p1@THAP2!2.57!489.43!THAP2;;chr7:115670804..115670825,-!p1@TFEC!2.56!366.08!TFEC;;chr2:70142232..70142251,+!p1@MXD1!2.53!1802.22!MXD1;;chr12:54778471..54778528,-!p1@ZNF385A!2.46!284.35!ZNF385A;;chr3:101546827..101546847,+!p2@NFKBIZ!2.35!311.29!NFKBIZ;;chr14:35872453..35872485,-!p2@NFKBIA!2.33!506.87!NFKBIA;;chr9:102584159..102584174,+!p2@NR4A3!2.31!357.20!NR4A3;;chr9:102584262..102584276,+!p1@NR4A3!2.29!414.44!NR4A3;;chr10:35484053..35484076,+!p1@CREM!2.27!444.13!CREM;;chr11:47400062..47400077,-!p2@SPI1!2.18!149.68!SPI1;;chr11:47399947..47399961,-!p3@SPI1!2.17!148.14!SPI1;;chr16:85932760..85932775,+!p1@IRF8!2.17!148.14!IRF8;;chr14:35873947..35873965,-!p1@NFKBIA!2.14!7966.75!NFKBIA;;chr3:101568349..101568365,+!p1@NFKBIZ!2.14!6627.02!NFKBIZ;;chr20:39317868..39317884,-!p1@MAFB!2.13!1497.67!MAFB;;chr19:45971246..45971265,+!p1@FOSB!2.09!2107.39!FOSB;;chr12:72056749..72056767,+!p6@THAP2!2.01!110.80!THAP2;;chr2:157189180..157189290,-!p1@NR4A2!1.98!469.84!NR4A2;;chr12:72056773..72056796,+!p3@THAP2!1.97!119.68!THAP2;;chr10:64018918..64018936,+!p2@ZNF365!1.96!89.38!ZNF365;;chr10:64576105..64576133,-!p1@EGR2!1.95!174.47!EGR2;;chr12:52445218..52445237,+!p1@NR4A1!1.93!988.65!NR4A1;;chr4:103422499..103422632,+!p1@NFKB1!1.91!1581.84!NFKB1;;chr11:47399996..47400014,-!p4@SPI1!1.90!78.66!SPI1;;chr9:102584128..102584144,+!p3@NR4A3!1.88!140.19!NR4A3;;chr19:36391434..36391450,-!p1@NFKBID!1.87!138.96!NFKBID;;chr2:192015701..192015743,-!p1@STAT4!1.87!99.17!STAT4;;chr11:47400032..47400043,-!p5@SPI1!1.86!71.32!SPI1;;chr2:70167296..70167306,+!p3@MXD1!1.85!104.68!MXD1;;chr4:83822199..83822239,+!p2@THAP9!1.85!82.34!THAP9;;chr8:22550982..22550999,-!p1@EGR3!1.84!184.87!EGR3;;chr9:102584241..102584261,+!p4@NR4A3!1.81!96.42!NR4A3;;chr16:31885093..31885165,+!p1@ZNF267!1.80!883.66!ZNF267;;chr19:50432132..50432217,+!p2@ATF5!1.79!71.93!ATF5;;chrX:153305787..153305807,-!p3@MECP2!1.79!60.91!MECP2;;chr10:104155480..104155534,+!p2@NFKB2!1.77!354.45!NFKB2;;chr2:145275162..145275202,-!p2@ZEB2!1.76!319.86!ZEB2;;chr1:25256756..25256774,-!p1@RUNX3!1.76!103.76!RUNX3;;chr10:51572408..51572454,+!p3@NCOA4!1.75!309.45!NCOA4;;chr6:106534192..106534224,+!p1@PRDM1!1.74!146.92!PRDM1;;chr14:35872494..35872511,-!p5@NFKBIA!1.74!70.09!NFKBIA;;chr2:145277640..145277771,-!p1@ZEB2!1.73!665.43!ZEB2;;chr10:31288398..31288455,-!p2@ZNF438!1.72!60.30!ZNF438;;chr2:68592394..68592405,+!p2@PLEK!1.72!51.12!PLEK;;chr1:212782094..212782109,+!p1@ATF3!1.71!1283.72!ATF3;;chr22:38597987..38598021,+!p2@MAFF!1.71!289.86!MAFF;;chr1:37940170..37940190,+!p1@ZC3H12A!1.70!565.95!ZC3H12A;;chr11:615942..615957,-!p1@IRF7!1.70!443.82!IRF7;;chr6:126240442..126240459,+!p4@NCOA7!1.70!62.44!NCOA7;;chr6:126240380..126240430,+!p2@NCOA7!1.69!119.07!NCOA7;;chr14:35872926..35872951,-!p4@NFKBIA!1.69!67.34!NFKBIA;;chr2:61108695..61108753,+!p1@REL!1.68!303.94!REL;;chr8:123793988..123794016,+!p1@ZHX2!1.68!81.42!ZHX2;;chr10:104155659..104155676,+!p4@NFKB2!1.68!58.16!NFKB2;;chr21:34442439..34442455,+!p1@OLIG1!1.67!45.91!OLIG1;;chr10:51572339..51572376,+!p4@NCOA4!1.65!95.19!NCOA4;;chr2:70165961..70165981,+!p8@MXD1!1.65!43.77!MXD1;;chr12:54778351..54778378,-!p6@ZNF385A!1.64!42.85!ZNF385A;;chr14:35872414..35872425,-!p7@NFKBIA!1.63!46.52!NFKBIA;;chr10:31288370..31288393,-!p3@ZNF438!1.63!41.93!ZNF438;;chr10:35484090..35484104,+!p6@CREM!1.63!41.32!CREM;;chr20:48599506..48599526,+!p1@SNAI1!1.62!252.21!SNAI1;;chr7:106809470..106809481,+!p2@HBP1!1.62!56.63!HBP1;;chr3:39195037..39195069,-!p2@CSRNP1!1.61!238.44!CSRNP1;;chr14:35872542..35872553,-!p10@NFKBIA!1.61!39.48!NFKBIA;;chr10:104154246..104154347,+!p3@NFKB2!1.60!227.73!NFKB2;;chr14:35872962..35873025,-!p3@NFKBIA!1.60!95.80!NFKBIA;;chr4:106066712..106066728,+!p8@TET2!1.60!38.87!TET2;;chr6:144385698..144385742,-!p2@PLAGL1!1.59!45.91!PLAGL1;;chr9:102584278..102584285,+!p5@NR4A3!1.58!37.34!NR4A3;;chrX:2418949..2419024,-!p1@DHRSX,p1@ZBED1!1.58!37.04!ZBED1;;chr21:36260295..36260310,-!p3@RUNX1!1.57!57.54!RUNX1;;chr6:126240463..126240489,+!p6@NCOA7!1.57!40.10!NCOA7;;chr4:106066776..106066791,+!p9@TET2!1.57!35.81!TET2;;chr6:12012170..12012245,+!p1@HIVEP1!1.56!169.57!HIVEP1;;chr2:145271342..145271377,-!p5@ZEB2!1.56!35.51!ZEB2;;chrX:129244454..129244488,-!p1@ELF4!1.55!237.22!ELF4;;chr2:97202480..97202499,+!p1@ARID5A!1.54!322.61!ARID5A;;chr9:129567282..129567353,+!p1@ZBTB43!1.52!402.50!ZBTB43;;chr6:44233252..44233296,-!p1@NFKBIE!1.52!303.02!NFKBIE;;chr18:3449330..3449344,+!p10@TGIF1!1.52!41.93!TGIF1;;chr19:54058073..54058088,+!p1@ZNF331!1.52!31.83!ZNF331;;chr19:45252008..45252024,+!p2@BCL3!1.50!97.33!BCL3;;chr2:70314240..70314256,+!p4@PCBP1!1.50!61.83!PCBP1;;chr2:70166156..70166179,+!p4@MXD1!1.50!30.30!MXD1;;chr13:41593425..41593480,-!p1@ELF1!1.49!184.26!ELF1;;chr5:137804484..137804498,+!p2@EGR1!1.49!115.70!EGR1;;chr19:47616992..47617011,-!p4@ZC3H4!1.49!62.14!ZC3H4;;chr11:47399920..47399931,-!p7@SPI1!1.49!30.00!SPI1;;chr3:150126101..150126118,+!p6@TSC22D2!1.48!46.52!TSC22D2;;chr21:40177845..40177863,+!p1@ETS2!1.47!1590.11!ETS2;;chr4:106068026..106068084,+!p1@TET2!1.47!245.79!TET2;;chrX:153305962..153305995,-!p5@MECP2!1.47!28.77!MECP2;;chr1:38325227..38325246,-!p2@MTF1!1.46!37.95!MTF1;;chr4:103423079..103423112,+!p4@NFKB1!1.46!28.16!NFKB1;;chr11:47400045..47400060,-!p6@SPI1!1.46!28.16!SPI1;;chr2:191885737..191885750,-!p4@STAT1!1.46!27.85!STAT1;;chr6:15246200..15246214,+!p2@JARID2!1.45!74.07!JARID2;;chr21:30673091..30673135,+!p7@BACH1!1.45!27.24!BACH1;;chr10:35416142..35416169,+!p3@CREM!1.44!68.56!CREM;;chr11:65430554..65430579,-!p3@RELA!1.44!65.81!RELA;;chr1:221052776..221052799,+!p1@HLX!1.44!47.44!HLX;;chr4:106066730..106066754,+!p6@TET2!1.44!26.63!TET2;;chr2:231090471..231090504,+!p2@SP140!1.44!26.32!SP140;;chr2:70166258..70166288,+!p5@MXD1!1.44!26.32!MXD1;;chr7:50344289..50344323,+!p1@IKZF1!1.44!26.32!IKZF1;;chr6:12011943..12012015,+!p2@HIVEP1!1.43!80.81!HIVEP1;;chr6:391743..391759,+!p1@IRF4!1.43!25.71!IRF4;;chr2:68615063..68615089,+!p4@PLEK!1.42!25.40!PLEK;;chr10:3827371..3827386,-!p2@KLF6!1.41!199.26!KLF6;;chr2:70166988..70167021,+!p7@MXD1!1.41!24.79!MXD1;;chr21:30671690..30671762,+!p2@BACH1!1.40!79.28!BACH1;;chr2:28618532..28618610,+!p4@FOSL2!1.40!40.40!FOSL2;;chr3:101575889..101575903,+!p3@NFKBIZ!1.39!23.57!NFKBIZ;;chr4:83822246..83822277,+!p5@THAP9!1.39!23.57!THAP9;;chr6:106534230..106534254,+!p2@PRDM1!1.38!56.32!PRDM1;;chr18:3448455..3448480,+!p5@TGIF1!1.38!41.63!TGIF1;;chr2:231090433..231090469,+!p1@SP140!1.38!23.26!SP140;;chr21:30671235..30671253,+!p1@BACH1!1.37!275.78!BACH1;;chr18:77155922..77155939,+!p1@NFATC1!1.37!60.91!NFATC1;;chr18:3449720..3449749,+!p2@TGIF1!1.37!46.52!TGIF1;;chr2:145277882..145277967,-!p3@ZEB2!1.37!37.95!ZEB2;;chr9:94173455..94173468,-!p4@NFIL3!1.37!22.34!NFIL3;;chr10:104155455..104155479,+!p1@NFKB2!1.36!308.53!NFKB2;;chr12:48298765..48298783,-!p2@VDR!1.36!45.30!VDR;;chr4:83821967..83821998,+!p3@THAP9!1.35!26.32!THAP9;;chr2:73520667..73520683,-!p1@EGR4!1.35!21.43!EGR4;;chr21:30672433..30672464,+!p6@BACH1!1.35!21.43!BACH1;;chr12:11802753..11802834,+!p2@ETV6!1.34!100.70!ETV6;;chr21:40177892..40177903,+!p2@ETS2!1.34!81.11!ETS2;;chr10:35484804..35484902,+!p2@CREM!1.34!77.44!CREM;;chr12:96588368..96588394,+!p3@ELK3!1.34!54.79!ELK3;;chr6:12012249..12012266,+!p5@HIVEP1!1.34!36.12!HIVEP1;;chr2:231084639..231084654,-!p2@SP110!1.34!34.59!SP110;;chr12:72056897..72056908,+!p12@THAP2!1.34!21.12!THAP2;;chr2:28615716..28615733,+!p1@FOSL2!1.33!928.35!FOSL2;;chr2:70142189..70142223,+!p2@MXD1!1.32!139.57!MXD1;;chr2:192015677..192015691,-!p3@STAT4!1.32!19.90!STAT4;;chr12:72056706..72056717,+!p10@THAP2!1.32!19.90!THAP2;;chr17:38497662..38497713,+!p4@RARA!1.31!22.34!RARA;;chr4:83822294..83822306,+!p8@THAP9!1.31!19.28!THAP9;;chr3:170075436..170075520,+!p1@SKIL!1.30!399.75!SKIL;;chr7:128577972..128578047,+!p1@IRF5!1.30!29.38!IRF5;;chr19:54041669..54041697,+!p2@ZNF331!1.30!18.98!ZNF331;;chr7:115670792..115670797,-!p2@TFEC!1.29!18.67!TFEC;;chrX:129244430..129244442,-!p5@ELF4!1.29!18.67!ELF4;;chrX:153305741..153305753,-!p4@MECP2!1.29!18.37!MECP2;;chr14:75745523..75745537,+!p1@FOS!1.28!2090.55!FOS;;chr11:615570..615721,-!p2@IRF7!1.28!35.20!IRF7;;chr2:238600998..238601013,+!p5@LRRFIP1!1.28!18.06!LRRFIP1;;chr18:3449618..3449634,+!p13@TGIF1!1.26!21.12!TGIF1;;chr2:238600933..238600985,+!p3@LRRFIP1!1.25!88.46!LRRFIP1;;chr19:45250948..45250998,+!p3@BCL3!1.25!41.63!BCL3;;chr18:3449586..3449617,+!p8@TGIF1!1.25!26.63!TGIF1;;chr3:39195139..39195150,-!p3@CSRNP1!1.25!21.43!CSRNP1;;chr12:96588219..96588263,+!p2@ELK3!1.24!115.70!ELK3;;chr4:81104895..81104920,+!p2@PRDM8!1.24!24.49!PRDM8;;chr3:39195075..39195088,-!p1@CSRNP1!1.23!98.56!CSRNP1;;chr5:142782823..142782854,-!p3@NR3C1!1.23!22.96!NR3C1;;chr9:110252035..110252057,-!p1@KLF4!1.22!242.11!KLF4;;chr7:17338266..17338282,+!p1@AHR!1.22!165.29!AHR;;chr2:157199008..157199023,-!p3@NR4A2!1.22!32.44!NR4A2;;chr10:3827389..3827408,-!p1@KLF6!1.21!1148.12!KLF6;;chr1:158979872..158979898,+!p3@IFI16!1.21!46.22!IFI16;;chr9:3525727..3525828,-!p2@RFX3!1.21!38.26!RFX3;;chr19:19496539..19496576,+!p8@GATAD2A!1.21!26.63!GATAD2A;;chr2:61108808..61108821,+!p3@REL!1.21!19.28!REL;;chr20:48807351..48807384,+!p1@CEBPB!1.20!1481.14!CEBPB;;chr1:157108130..157108173,-!p1@ETV3!1.20!105.29!ETV3;;chr2:208394817..208394834,+!p3@CREB1!1.20!59.69!CREB1;;chr1:161736038..161736056,+!p4@ATF6!1.20!34.59!ATF6;;chr8:116681123..116681143,-!p4@TRPS1!1.20!28.77!TRPS1;;chr18:3449527..3449582,+!p6@TGIF1!1.20!28.47!TGIF1;;chr17:40440225..40440268,+!p3@STAT5A!1.20!18.98!STAT5A;;chr11:65430535..65430549,-!p4@RELA!1.20!17.45!RELA;;chr17:38497715..38497734,+!p8@RARA!1.20!15.00!RARA;;chr8:53373491..53373506,-!p4@ST18!1.20!15.00!ST18;;chr12:72056684..72056693,+!p13@THAP2!1.20!14.69!THAP2;;chr2:70166499..70166536,+!p6@MXD1!1.20!14.69!MXD1;;chr19:12902289..12902307,+!p1@JUNB!1.19!3252.14!JUNB;;chr9:117150254..117150271,-!p1@AKNA!1.19!39.79!AKNA;;chr8:72755203..72755239,-!p10@MSC!1.18!14.08!MSC;;chr2:145277589..145277612,-!p12@Z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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000222;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000234;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000576;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000763;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000766;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000860;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002193;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002390;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002405 | |||
|ffid_belonging_in_development=CL:0000049,CL:0000134,CL:0002057 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 41: | ||
|fonse_treatment=FF:0000625,FF:0000632,FF:0011106,FF:11864-125B1 | |fonse_treatment=FF:0000625,FF:0000632,FF:0011106,FF:11864-125B1 | ||
|fonse_treatment_closure=FF:0000625,FF:0000632,FF:0011106,FF:11864-125B1 | |fonse_treatment_closure=FF:0000625,FF:0000632,FF:0011106,FF:11864-125B1 | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Group%2520A%2520streptococci%252c%2520donor1.CNhs13469.11864-125B1.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Group%2520A%2520streptococci%252c%2520donor1.CNhs13469.11864-125B1.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Group%2520A%2520streptococci%252c%2520donor1.CNhs13469.11864-125B1.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Group%2520A%2520streptococci%252c%2520donor1.CNhs13469.11864-125B1.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Group%2520A%2520streptococci%252c%2520donor1.CNhs13469.11864-125B1.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11864-125B1 | |||
|is_a=EFO:0002091;;FF:0011106 | |||
|is_obsolete= | |||
|library_id=CNhs13469 | |||
|library_id_phase_based=2:CNhs13469 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11864 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11864 | |||
|name=CD14+ monocytes - treated with Group A streptococci, donor1 | |||
|namespace= | |namespace= | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs13469,LSID1024,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0.282905586573266,0.435428982216526,0,0,0,0.207410238582937,0.336969313611106,0,0.472676264313991,0.500573000735142,0,0.115971073434934,0.115971073434934,0,0,0,0,0,0,0,0.403192519147754,0.574581607915811,0,0.455292752859483,0,0,0,0.348575014441098,0,0.184947690305209,0,1.17408499469365,0.536639814708127,0,0,0,0.299900697039839,0,0.057985536717467,0,1.06866577892667,0,0.347200306732594,0,0,0.272455200270764,0.347200306732594,0,0,0,0.40677415134375,0,0.115971073434934,0,0.0337705156046327,0,0,0,0.115971073434934,0,-0.034457721101237,0.115971073434934,0.543183154734881,0,0.60861576320791,-0.097343627213097,0,1.23776305286745,0,0,0,0.115971073434934,0.282905586573266,0.115971073434934,0.207410238582937,0,0.452783301463467,0,0,0.497287343697492,0,0,0,0.0796690244785424,0,0,0,0.057985536717467,0,0,-0.552571649267773,0,0,0,-0.0584468268118252,0.115614025299042,0.057985536717467,0,1.42534641387781,0,0.249164955494888,0.45569180587941,0,0,0.103705119291469,0,0,1.07013706328052,0.115971073434934,0,0,0,0,0,0.516954556287266,0,0,0,0,0.0073315253690075,0.282905586573266,0,0,0.311875858378218,0.29807540242908,0,1.34478097155847,0.391497712324812,0,0,0 | |||
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| |||
|rna_box=125 | |||
|rna_catalog_number= | |||
|rna_concentration=0.8576 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number=D3-5 | |||
|rna_od260/230=1.86 | |||
|rna_od260/280=2.03 | |||
|rna_position=B1 | |||
|rna_rin=9.8 | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=125B1 | |||
|rna_weight_ug=4.288 | |||
|sample_age=69 | |||
|sample_category=primary cells | |||
|sample_cell_catalog= | |||
|sample_cell_line= | |||
|sample_cell_lot= | |||
|sample_cell_type=monocyte | |||
|sample_collaboration=Christine Wells (University of Queensland) | |||
|sample_company= | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease= | |||
|sample_donor(cell lot)=donor1 | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.01786470607794e-292!GO:0005737;cytoplasm;1.78749776881415e-124!GO:0043227;membrane-bound organelle;4.27205572324574e-103!GO:0043231;intracellular membrane-bound organelle;7.52008433801856e-103!GO:0043226;organelle;1.86456187795496e-95!GO:0043229;intracellular organelle;9.21418932043066e-95!GO:0044444;cytoplasmic part;7.85762938876132e-80!GO:0005515;protein binding;3.90770039026641e-76!GO:0044422;organelle part;8.23745115869727e-66!GO:0044446;intracellular organelle part;2.64454351589453e-64!GO:0044237;cellular metabolic process;1.03978253189712e-57!GO:0044238;primary metabolic process;3.74796547390322e-57!GO:0032991;macromolecular complex;3.74796547390322e-57!GO:0043170;macromolecule metabolic process;1.51694453982788e-54!GO:0003723;RNA binding;8.17068240148158e-51!GO:0019538;protein metabolic process;1.55675798788358e-46!GO:0030529;ribonucleoprotein complex;5.69966087986883e-46!GO:0044267;cellular protein metabolic process;5.30474851879256e-43!GO:0044260;cellular macromolecule metabolic process;1.03312431100672e-42!GO:0044428;nuclear part;1.27465282456898e-42!GO:0033036;macromolecule localization;6.18193446282952e-42!GO:0015031;protein transport;1.85140226330584e-41!GO:0045184;establishment of protein localization;1.90544966404652e-41!GO:0006412;translation;2.67151583492102e-39!GO:0008104;protein localization;3.40244331421319e-39!GO:0005634;nucleus;4.45460919942743e-39!GO:0006915;apoptosis;1.32035673011386e-35!GO:0012501;programmed cell death;1.55947447507815e-35!GO:0005829;cytosol;2.49482229863524e-35!GO:0008219;cell death;5.6532274539156e-34!GO:0016265;death;5.6532274539156e-34!GO:0043233;organelle lumen;2.55185813210906e-33!GO:0031974;membrane-enclosed lumen;2.55185813210906e-33!GO:0031090;organelle membrane;7.63558233799802e-33!GO:0043234;protein complex;3.15475009776385e-30!GO:0009059;macromolecule biosynthetic process;1.24189591651225e-29!GO:0016071;mRNA metabolic process;1.66685300822546e-29!GO:0046907;intracellular transport;4.97881946027715e-28!GO:0043283;biopolymer metabolic process;9.09376357885074e-28!GO:0016043;cellular component organization and biogenesis;2.27702049139671e-27!GO:0006886;intracellular protein transport;3.13217140781079e-27!GO:0009058;biosynthetic process;4.01430646478452e-27!GO:0044249;cellular biosynthetic process;5.90293327347027e-27!GO:0010467;gene expression;2.22354816481462e-26!GO:0006396;RNA processing;4.88362601230901e-26!GO:0031981;nuclear lumen;7.41123973801746e-26!GO:0008380;RNA splicing;3.787885713016e-25!GO:0005840;ribosome;6.28981132203292e-25!GO:0006397;mRNA processing;1.85452142970046e-24!GO:0042981;regulation of apoptosis;2.99913990804507e-24!GO:0031967;organelle envelope;2.99913990804507e-24!GO:0031975;envelope;5.62941074024316e-24!GO:0005739;mitochondrion;6.76346683649163e-24!GO:0043067;regulation of programmed cell death;7.24785360626535e-24!GO:0003735;structural constituent of ribosome;2.8726930544997e-23!GO:0005830;cytosolic ribosome (sensu Eukaryota);4.14903372434425e-23!GO:0033279;ribosomal subunit;1.39838463429726e-22!GO:0051649;establishment of cellular localization;3.75080889985914e-22!GO:0002376;immune system process;9.47591306766188e-22!GO:0044445;cytosolic part;1.11756304827829e-21!GO:0051641;cellular localization;1.74395008065534e-21!GO:0007243;protein kinase cascade;3.15041229853821e-21!GO:0008134;transcription factor binding;5.64242587598511e-21!GO:0065003;macromolecular complex assembly;2.46007846696772e-20!GO:0016192;vesicle-mediated transport;1.32207136339998e-19!GO:0005681;spliceosome;1.5401875344658e-19!GO:0000166;nucleotide binding;2.34579483522998e-19!GO:0005654;nucleoplasm;3.44451605102877e-19!GO:0044429;mitochondrial part;9.23609530646184e-19!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;4.42534957214457e-18!GO:0006955;immune response;7.36739844501686e-18!GO:0007249;I-kappaB kinase/NF-kappaB cascade;2.25262375434304e-17!GO:0048523;negative regulation of cellular process;2.41106936061627e-17!GO:0022607;cellular component assembly;4.48352103034078e-17!GO:0044265;cellular macromolecule catabolic process;7.70372554326118e-17!GO:0006119;oxidative phosphorylation;1.6467343896279e-16!GO:0006512;ubiquitin cycle;1.78326781639084e-16!GO:0043412;biopolymer modification;2.08952747004235e-16!GO:0048770;pigment granule;2.27917001840589e-16!GO:0042470;melanosome;2.27917001840589e-16!GO:0007242;intracellular signaling cascade;2.30882274943729e-16!GO:0044451;nucleoplasm part;4.97814557307568e-16!GO:0048519;negative regulation of biological process;1.03852257969819e-15!GO:0005740;mitochondrial envelope;1.16469685114658e-15!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;1.64059173569685e-15!GO:0006464;protein modification process;1.76547875762729e-15!GO:0005773;vacuole;1.93547631198903e-15!GO:0031966;mitochondrial membrane;2.33917070207485e-15!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;3.32345393752729e-15!GO:0016462;pyrophosphatase activity;3.64064672468965e-15!GO:0065009;regulation of a molecular function;3.77235836969748e-15!GO:0043687;post-translational protein modification;4.06406347916745e-15!GO:0016817;hydrolase activity, acting on acid anhydrides;4.49213269545109e-15!GO:0017111;nucleoside-triphosphatase activity;4.86032683794299e-15!GO:0006605;protein targeting;6.0930247774004e-15!GO:0019866;organelle inner membrane;6.48065162395938e-15!GO:0043069;negative regulation of programmed cell death;8.25126551159814e-15!GO:0043066;negative regulation of apoptosis;9.46159752516776e-15!GO:0043285;biopolymer catabolic process;2.88868624665501e-14!GO:0032553;ribonucleotide binding;3.72453880509127e-14!GO:0032555;purine ribonucleotide binding;3.72453880509127e-14!GO:0022613;ribonucleoprotein complex biogenesis and assembly;4.29091663057401e-14!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;4.73627712843867e-14!GO:0006950;response to stress;5.19832166566526e-14!GO:0019941;modification-dependent protein catabolic process;7.39720790623454e-14!GO:0043632;modification-dependent macromolecule catabolic process;7.39720790623454e-14!GO:0022618;protein-RNA complex assembly;8.00569956139421e-14!GO:0051603;proteolysis involved in cellular protein catabolic process;9.88511838033919e-14!GO:0000323;lytic vacuole;1.00345651545726e-13!GO:0005764;lysosome;1.00345651545726e-13!GO:0044257;cellular protein catabolic process;1.10617987322537e-13!GO:0009057;macromolecule catabolic process;1.57379219384305e-13!GO:0009615;response to virus;1.60546769328747e-13!GO:0006511;ubiquitin-dependent protein catabolic process;1.66794403543669e-13!GO:0017076;purine nucleotide binding;1.69204267373111e-13!GO:0006913;nucleocytoplasmic transport;1.95763159605324e-13!GO:0051246;regulation of protein metabolic process;2.76696711850297e-13!GO:0051169;nuclear transport;3.91345397790432e-13!GO:0048522;positive regulation of cellular process;5.17724337301057e-13!GO:0050794;regulation of cellular process;6.92915250719508e-13!GO:0016604;nuclear body;6.97767597608518e-13!GO:0003712;transcription cofactor activity;7.66549021194389e-13!GO:0006793;phosphorus metabolic process;8.47780516133579e-13!GO:0006796;phosphate metabolic process;8.47780516133579e-13!GO:0044248;cellular catabolic process;1.03826871692452e-12!GO:0005768;endosome;1.27126437558183e-12!GO:0005794;Golgi apparatus;2.0953793353418e-12!GO:0005743;mitochondrial inner membrane;2.0953793353418e-12!GO:0015934;large ribosomal subunit;2.54407697566489e-12!GO:0012505;endomembrane system;2.55322491487533e-12!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);3.22845300494841e-12!GO:0006916;anti-apoptosis;4.15083630604392e-12!GO:0048518;positive regulation of biological process;5.55283136417097e-12!GO:0006996;organelle organization and biogenesis;8.07276797603692e-12!GO:0016874;ligase activity;8.78646304904798e-12!GO:0016310;phosphorylation;9.38114252678175e-12!GO:0006366;transcription from RNA polymerase II promoter;9.38114252678175e-12!GO:0044455;mitochondrial membrane part;9.97980507473808e-12!GO:0000502;proteasome complex (sensu Eukaryota);1.16044438309738e-11!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.21389252853655e-11!GO:0030163;protein catabolic process;1.47179088514271e-11!GO:0050790;regulation of catalytic activity;2.28413588235768e-11!GO:0015935;small ribosomal subunit;2.35620537913941e-11!GO:0008135;translation factor activity, nucleic acid binding;3.75581492865361e-11!GO:0016607;nuclear speck;4.0497285113958e-11!GO:0009607;response to biotic stimulus;4.3925704963568e-11!GO:0050789;regulation of biological process;1.09924767334125e-10!GO:0009967;positive regulation of signal transduction;2.67713734678374e-10!GO:0003676;nucleic acid binding;2.97111437751238e-10!GO:0003743;translation initiation factor activity;3.01038295262033e-10!GO:0006417;regulation of translation;3.03182714530171e-10!GO:0065007;biological regulation;4.08016347002572e-10!GO:0043065;positive regulation of apoptosis;4.12528758834881e-10!GO:0016070;RNA metabolic process;4.41946232321728e-10!GO:0048468;cell development;4.98944379408868e-10!GO:0043068;positive regulation of programmed cell death;6.40888824183104e-10!GO:0006413;translational initiation;6.93593063090868e-10!GO:0006457;protein folding;8.03978302202777e-10!GO:0016787;hydrolase activity;9.76354671974148e-10!GO:0005524;ATP binding;1.07004869741845e-09!GO:0008639;small protein conjugating enzyme activity;1.14902871536856e-09!GO:0006259;DNA metabolic process;1.216370695231e-09!GO:0032559;adenyl ribonucleotide binding;1.49255699467831e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.62719136324607e-09!GO:0004842;ubiquitin-protein ligase activity;1.72424980092757e-09!GO:0006446;regulation of translational initiation;1.82351360455435e-09!GO:0005746;mitochondrial respiratory chain;1.85586196689523e-09!GO:0051186;cofactor metabolic process;1.95748439639057e-09!GO:0019787;small conjugating protein ligase activity;2.13403523499774e-09!GO:0019829;cation-transporting ATPase activity;3.39527544712985e-09!GO:0031324;negative regulation of cellular metabolic process;6.47827300720917e-09!GO:0005783;endoplasmic reticulum;6.47827300720917e-09!GO:0048193;Golgi vesicle transport;6.53331538001475e-09!GO:0030554;adenyl nucleotide binding;6.73652953701579e-09!GO:0009889;regulation of biosynthetic process;6.73652953701579e-09!GO:0017038;protein import;6.88283095693707e-09!GO:0005635;nuclear envelope;7.59209278872207e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;8.18233065955998e-09!GO:0051170;nuclear import;9.11586050574774e-09!GO:0015986;ATP synthesis coupled proton transport;1.03609572120203e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.03609572120203e-08!GO:0050136;NADH dehydrogenase (quinone) activity;1.07524495524207e-08!GO:0003954;NADH dehydrogenase activity;1.07524495524207e-08!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.07524495524207e-08!GO:0006917;induction of apoptosis;1.13776245460824e-08!GO:0009056;catabolic process;1.22657021552765e-08!GO:0019899;enzyme binding;1.36537695876858e-08!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.44159044538108e-08!GO:0031326;regulation of cellular biosynthetic process;1.50143334963495e-08!GO:0005770;late endosome;1.72097291836812e-08!GO:0012502;induction of programmed cell death;1.99101474574486e-08!GO:0000398;nuclear mRNA splicing, via spliceosome;2.04700848709902e-08!GO:0000375;RNA splicing, via transesterification reactions;2.04700848709902e-08!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;2.04700848709902e-08!GO:0006732;coenzyme metabolic process;2.13617301583277e-08!GO:0006606;protein import into nucleus;2.13617301583277e-08!GO:0051082;unfolded protein binding;2.6209572016563e-08!GO:0051726;regulation of cell cycle;3.17947940461661e-08!GO:0000074;regulation of progression through cell cycle;4.03135740534483e-08!GO:0016564;transcription repressor activity;4.78600251557251e-08!GO:0009152;purine ribonucleotide biosynthetic process;4.8684874675105e-08!GO:0007049;cell cycle;5.04710150993814e-08!GO:0003713;transcription coactivator activity;6.0782062299363e-08!GO:0006164;purine nucleotide biosynthetic process;6.66407366769153e-08!GO:0009150;purine ribonucleotide metabolic process;6.6888723031673e-08!GO:0006163;purine nucleotide metabolic process;8.12727777606674e-08!GO:0016887;ATPase activity;9.33615839472258e-08!GO:0042623;ATPase activity, coupled;1.13252924548247e-07!GO:0009892;negative regulation of metabolic process;1.15281575870292e-07!GO:0006754;ATP biosynthetic process;1.17902026422451e-07!GO:0006753;nucleoside phosphate metabolic process;1.17902026422451e-07!GO:0003924;GTPase activity;1.3093125011597e-07!GO:0016881;acid-amino acid ligase activity;1.32922715982154e-07!GO:0042775;organelle ATP synthesis coupled electron transport;1.65797881682221e-07!GO:0042773;ATP synthesis coupled electron transport;1.65797881682221e-07!GO:0005774;vacuolar membrane;1.78280824242442e-07!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.79524807819244e-07!GO:0009259;ribonucleotide metabolic process;1.8186914402621e-07!GO:0045786;negative regulation of progression through cell cycle;1.83985111616887e-07!GO:0006952;defense response;2.27020175459005e-07!GO:0030964;NADH dehydrogenase complex (quinone);2.2997837137881e-07!GO:0045271;respiratory chain complex I;2.2997837137881e-07!GO:0005747;mitochondrial respiratory chain complex I;2.2997837137881e-07!GO:0016469;proton-transporting two-sector ATPase complex;2.35221067915025e-07!GO:0016879;ligase activity, forming carbon-nitrogen bonds;2.42073101568259e-07!GO:0044432;endoplasmic reticulum part;2.42469664153738e-07!GO:0005525;GTP binding;2.50134586135987e-07!GO:0006461;protein complex assembly;2.69878841711134e-07!GO:0044440;endosomal part;2.90024371237306e-07!GO:0010008;endosome membrane;2.90024371237306e-07!GO:0031965;nuclear membrane;2.94554626615217e-07!GO:0015078;hydrogen ion transmembrane transporter activity;3.01736842640124e-07!GO:0008047;enzyme activator activity;3.03582296651242e-07!GO:0009260;ribonucleotide biosynthetic process;3.11489731995986e-07!GO:0016044;membrane organization and biogenesis;3.25399926178385e-07!GO:0007264;small GTPase mediated signal transduction;4.20410946197909e-07!GO:0051707;response to other organism;4.22075722061182e-07!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;4.79971954028821e-07!GO:0006954;inflammatory response;4.85254439372972e-07!GO:0009966;regulation of signal transduction;4.85254439372972e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;5.02900722642938e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;5.02900722642938e-07!GO:0005730;nucleolus;5.83731380195485e-07!GO:0044453;nuclear membrane part;6.02617774765565e-07!GO:0009055;electron carrier activity;6.06898021217271e-07!GO:0009142;nucleoside triphosphate biosynthetic process;6.99285772528055e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;6.99285772528055e-07!GO:0046034;ATP metabolic process;8.44600511414137e-07!GO:0044437;vacuolar part;8.67009389044396e-07!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;8.67009389044396e-07!GO:0005793;ER-Golgi intermediate compartment;1.15630437659016e-06!GO:0005765;lysosomal membrane;1.21961805214542e-06!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.76919306745452e-06!GO:0009144;purine nucleoside triphosphate metabolic process;1.76919306745452e-06!GO:0016563;transcription activator activity;1.98849448391865e-06!GO:0051188;cofactor biosynthetic process;2.07448118111721e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;2.1018664571488e-06!GO:0009199;ribonucleoside triphosphate metabolic process;2.27807798017969e-06!GO:0043228;non-membrane-bound organelle;2.47018389801882e-06!GO:0043232;intracellular non-membrane-bound organelle;2.47018389801882e-06!GO:0045321;leukocyte activation;2.48035992682982e-06!GO:0030099;myeloid cell differentiation;2.48097085574821e-06!GO:0030097;hemopoiesis;2.6217399780377e-06!GO:0008565;protein transporter activity;2.7060863289191e-06!GO:0016481;negative regulation of transcription;3.20071770331685e-06!GO:0001816;cytokine production;3.25296681022877e-06!GO:0050657;nucleic acid transport;3.54448582746431e-06!GO:0051236;establishment of RNA localization;3.54448582746431e-06!GO:0050658;RNA transport;3.54448582746431e-06!GO:0009108;coenzyme biosynthetic process;3.98618282218792e-06!GO:0006752;group transfer coenzyme metabolic process;4.06838515983582e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;4.12322045769318e-06!GO:0051338;regulation of transferase activity;4.30770989081683e-06!GO:0031982;vesicle;4.46499991270897e-06!GO:0006403;RNA localization;4.93268089502529e-06!GO:0032561;guanyl ribonucleotide binding;5.15207072145262e-06!GO:0019001;guanyl nucleotide binding;5.15207072145262e-06!GO:0016197;endosome transport;5.38366707809363e-06!GO:0005789;endoplasmic reticulum membrane;5.45487629447961e-06!GO:0009141;nucleoside triphosphate metabolic process;5.57119238019983e-06!GO:0042175;nuclear envelope-endoplasmic reticulum network;5.93960294341763e-06!GO:0032446;protein modification by small protein conjugation;6.48425233585377e-06!GO:0005839;proteasome core complex (sensu Eukaryota);6.66711387700875e-06!GO:0051336;regulation of hydrolase activity;6.69812598871048e-06!GO:0003714;transcription corepressor activity;8.11937824755743e-06!GO:0006897;endocytosis;8.23530354096849e-06!GO:0010324;membrane invagination;8.23530354096849e-06!GO:0006357;regulation of transcription from RNA polymerase II promoter;8.55947339809981e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;8.55947339809981e-06!GO:0019222;regulation of metabolic process;9.41760560157351e-06!GO:0043549;regulation of kinase activity;9.87269736945596e-06!GO:0016568;chromatin modification;1.09707552768041e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;1.21769445152532e-05!GO:0015399;primary active transmembrane transporter activity;1.21769445152532e-05!GO:0016567;protein ubiquitination;1.22581222851154e-05!GO:0005643;nuclear pore;1.54410724849107e-05!GO:0009893;positive regulation of metabolic process;1.65133703974344e-05!GO:0006325;establishment and/or maintenance of chromatin architecture;1.65500036445738e-05!GO:0008026;ATP-dependent helicase activity;1.65634538604114e-05!GO:0045859;regulation of protein kinase activity;1.70868225500873e-05!GO:0043085;positive regulation of catalytic activity;1.77210444688251e-05!GO:0008632;apoptotic program;2.21040769349765e-05!GO:0004298;threonine endopeptidase activity;2.21040769349765e-05!GO:0004386;helicase activity;2.24203446401913e-05!GO:0005769;early endosome;2.24966769059992e-05!GO:0006888;ER to Golgi vesicle-mediated transport;2.29795491852345e-05!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;2.47083983249278e-05!GO:0031252;leading edge;2.58029751110848e-05!GO:0031410;cytoplasmic vesicle;2.64826507016413e-05!GO:0030695;GTPase regulator activity;2.88148939481134e-05!GO:0006401;RNA catabolic process;3.12409585208607e-05!GO:0030120;vesicle coat;3.28995789304571e-05!GO:0030662;coated vesicle membrane;3.28995789304571e-05!GO:0022402;cell cycle process;3.35489061567851e-05!GO:0048475;coated membrane;3.41472092412019e-05!GO:0030117;membrane coat;3.41472092412019e-05!GO:0051028;mRNA transport;3.58751431090683e-05!GO:0006323;DNA packaging;3.66155925721279e-05!GO:0031980;mitochondrial lumen;4.19226329227031e-05!GO:0005759;mitochondrial matrix;4.19226329227031e-05!GO:0031988;membrane-bound vesicle;4.20842002781367e-05!GO:0031902;late endosome membrane;4.54026629035823e-05!GO:0046822;regulation of nucleocytoplasmic transport;4.71675710464668e-05!GO:0006974;response to DNA damage stimulus;4.82186216238769e-05!GO:0005057;receptor signaling protein activity;5.16322884502123e-05!GO:0016740;transferase activity;6.17977232821305e-05!GO:0046649;lymphocyte activation;6.38638205111811e-05!GO:0009611;response to wounding;6.62732655198277e-05!GO:0043566;structure-specific DNA binding;6.80326863613702e-05!GO:0005096;GTPase activator activity;7.04078413160632e-05!GO:0032940;secretion by cell;7.53496522885144e-05!GO:0002520;immune system development;7.93826685655154e-05!GO:0002521;leukocyte differentiation;8.39582148333302e-05!GO:0045259;proton-transporting ATP synthase complex;8.58568820656988e-05!GO:0004674;protein serine/threonine kinase activity;8.81036178199503e-05!GO:0001775;cell activation;8.94688505165266e-05!GO:0051223;regulation of protein transport;9.1785960517011e-05!GO:0009060;aerobic respiration;9.29940264035342e-05!GO:0051427;hormone receptor binding;9.34868993454848e-05!GO:0048534;hemopoietic or lymphoid organ development;9.42784499858863e-05!GO:0051168;nuclear export;0.000100518776384235!GO:0043492;ATPase activity, coupled to movement of substances;0.000102896630004951!GO:0043281;regulation of caspase activity;0.000107547419954913!GO:0003697;single-stranded DNA binding;0.000108328704199065!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000113221393945412!GO:0007050;cell cycle arrest;0.000113848966827946!GO:0046930;pore complex;0.000122507611625696!GO:0006402;mRNA catabolic process;0.000127404084508838!GO:0016023;cytoplasmic membrane-bound vesicle;0.000129018924237855!GO:0043280;positive regulation of caspase activity;0.000137906998100549!GO:0051789;response to protein stimulus;0.000139332381086154!GO:0006986;response to unfolded protein;0.000139332381086154!GO:0006919;caspase activation;0.000139332381086154!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000142354451859087!GO:0035257;nuclear hormone receptor binding;0.000143674923478298!GO:0042110;T cell activation;0.000151014320921816!GO:0046519;sphingoid metabolic process;0.000153654589759447!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;0.000158288892269351!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;0.000160556147511057!GO:0006613;cotranslational protein targeting to membrane;0.000164591065972561!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000166886441834531!GO:0044431;Golgi apparatus part;0.000202568560521784!GO:0008234;cysteine-type peptidase activity;0.000211317709333357!GO:0022890;inorganic cation transmembrane transporter activity;0.000212428864303878!GO:0031325;positive regulation of cellular metabolic process;0.000212882955265037!GO:0006672;ceramide metabolic process;0.000218534181241073!GO:0030036;actin cytoskeleton organization and biogenesis;0.00021929809948716!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000235418141437097!GO:0051090;regulation of transcription factor activity;0.000251913879516227!GO:0003724;RNA helicase activity;0.000260173654331774!GO:0045637;regulation of myeloid cell differentiation;0.000262285541001018!GO:0065002;intracellular protein transport across a membrane;0.000262830527226056!GO:0005885;Arp2/3 protein complex;0.000293012817465038!GO:0005083;small GTPase regulator activity;0.00030791910593542!GO:0045333;cellular respiration;0.000312701733368565!GO:0045941;positive regulation of transcription;0.000314092521601352!GO:0006281;DNA repair;0.000357677395441521!GO:0060090;molecular adaptor activity;0.000379101683360969!GO:0007265;Ras protein signal transduction;0.000412163938795392!GO:0002757;immune response-activating signal transduction;0.000425628230267167!GO:0033157;regulation of intracellular protein transport;0.000437925153893391!GO:0042306;regulation of protein import into nucleus;0.000437925153893391!GO:0045893;positive regulation of transcription, DNA-dependent;0.000453026927675236!GO:0030532;small nuclear ribonucleoprotein complex;0.00045484332443103!GO:0019221;cytokine and chemokine mediated signaling pathway;0.000470528457898355!GO:0007034;vacuolar transport;0.000480434694230502!GO:0003729;mRNA binding;0.00048506862870307!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.000495237213736627!GO:0006818;hydrogen transport;0.00054716172464124!GO:0001726;ruffle;0.000580219009437289!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000611647915274031!GO:0000151;ubiquitin ligase complex;0.000614131695527369!GO:0007041;lysosomal transport;0.000618089417970569!GO:0006643;membrane lipid metabolic process;0.000631101278560089!GO:0015992;proton transport;0.000680002083537387!GO:0031323;regulation of cellular metabolic process;0.000680002083537387!GO:0005798;Golgi-associated vesicle;0.000681336035000079!GO:0046983;protein dimerization activity;0.000695867933234534!GO:0016301;kinase activity;0.00069722655588858!GO:0006612;protein targeting to membrane;0.00069722655588858!GO:0002274;myeloid leukocyte activation;0.000767052999365234!GO:0007005;mitochondrion organization and biogenesis;0.000782808715091463!GO:0031202;RNA splicing factor activity, transesterification mechanism;0.000787959205922544!GO:0000245;spliceosome assembly;0.000788610483891809!GO:0016281;eukaryotic translation initiation factor 4F complex;0.000807256117715634!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.000817193413271371!GO:0022415;viral reproductive process;0.000874342206950751!GO:0051345;positive regulation of hydrolase activity;0.00103916811074825!GO:0002764;immune response-regulating signal transduction;0.00103924964417069!GO:0019904;protein domain specific binding;0.00105022264680985!GO:0007040;lysosome organization and biogenesis;0.00112936136908095!GO:0009117;nucleotide metabolic process;0.00126598047665151!GO:0008654;phospholipid biosynthetic process;0.00128154793956813!GO:0042990;regulation of transcription factor import into nucleus;0.001285610801333!GO:0042991;transcription factor import into nucleus;0.001285610801333!GO:0007259;JAK-STAT cascade;0.00132762435634921!GO:0051276;chromosome organization and biogenesis;0.00142977582090767!GO:0042221;response to chemical stimulus;0.00145070167175305!GO:0045892;negative regulation of transcription, DNA-dependent;0.00148337894697522!GO:0001817;regulation of cytokine production;0.00153451259686726!GO:0030218;erythrocyte differentiation;0.00155127816708003!GO:0030149;sphingolipid catabolic process;0.00156641200606356!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00160997413036204!GO:0005667;transcription factor complex;0.00167934953439101!GO:0030029;actin filament-based process;0.00168018661450509!GO:0033116;ER-Golgi intermediate compartment membrane;0.00188884311825218!GO:0051023;regulation of immunoglobulin secretion;0.00193816722254777!GO:0045994;positive regulation of translational initiation by iron;0.00193816722254777!GO:0009719;response to endogenous stimulus;0.00202269895606825!GO:0044262;cellular carbohydrate metabolic process;0.0020807282427616!GO:0006468;protein amino acid phosphorylation;0.00209148662679339!GO:0002429;immune response-activating cell surface receptor signaling pathway;0.00219918860298637!GO:0007033;vacuole organization and biogenesis;0.00226161568960962!GO:0005637;nuclear inner membrane;0.00250168541552772!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.00255156422253117!GO:0042802;identical protein binding;0.00257870214294092!GO:0005761;mitochondrial ribosome;0.00267568623506544!GO:0000313;organellar ribosome;0.00267568623506544!GO:0006099;tricarboxylic acid cycle;0.00271450551246374!GO:0046356;acetyl-CoA catabolic process;0.00271450551246374!GO:0008186;RNA-dependent ATPase activity;0.00288629112374517!GO:0031901;early endosome membrane;0.00290688166132943!GO:0045045;secretory pathway;0.00311564986266642!GO:0002252;immune effector process;0.00322171048284975!GO:0005070;SH3/SH2 adaptor activity;0.00331733924998912!GO:0051059;NF-kappaB binding;0.00333963692262348!GO:0005741;mitochondrial outer membrane;0.00346679039532113!GO:0032386;regulation of intracellular transport;0.00351123720350522!GO:0001819;positive regulation of cytokine production;0.00357340885314957!GO:0016251;general RNA polymerase II transcription factor activity;0.00357844531822925!GO:0051092;activation of NF-kappaB transcription factor;0.00360250722703291!GO:0000139;Golgi membrane;0.00375650663580275!GO:0000165;MAPKKK cascade;0.00382577887014701!GO:0043623;cellular protein complex assembly;0.00383813302926479!GO:0004197;cysteine-type endopeptidase activity;0.0039234434347535!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00399940462117289!GO:0051187;cofactor catabolic process;0.00406700900318645!GO:0043433;negative regulation of transcription factor activity;0.00435355256692563!GO:0006091;generation of precursor metabolites and energy;0.00459696947157303!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00489678330171566!GO:0002768;immune response-regulating cell surface receptor signaling pathway;0.00497719239797794!GO:0005099;Ras GTPase activator activity;0.00500660684784195!GO:0051247;positive regulation of protein metabolic process;0.00500660684784195!GO:0065004;protein-DNA complex assembly;0.00514796019922525!GO:0018193;peptidyl-amino acid modification;0.00516157341647846!GO:0006611;protein export from nucleus;0.00516752107750966!GO:0042108;positive regulation of cytokine biosynthetic process;0.00522693596919148!GO:0008383;manganese superoxide dismutase activity;0.00527225976176553!GO:0001315;age-dependent response to reactive oxygen species;0.00527225976176553!GO:0045454;cell redox homeostasis;0.00529420752151441!GO:0010468;regulation of gene expression;0.00557385542103616!GO:0006665;sphingolipid metabolic process;0.00564132631879855!GO:0006935;chemotaxis;0.00577686081276709!GO:0042330;taxis;0.00577686081276709!GO:0019882;antigen processing and presentation;0.00594690224531188!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00594690224531188!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00594690224531188!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00594690224531188!GO:0043087;regulation of GTPase activity;0.00594690224531188!GO:0045646;regulation of erythrocyte differentiation;0.00600293915845853!GO:0006891;intra-Golgi vesicle-mediated transport;0.00600293915845853!GO:0033673;negative regulation of kinase activity;0.00607624326808443!GO:0006469;negative regulation of protein kinase activity;0.00607624326808443!GO:0042254;ribosome biogenesis and assembly;0.00607650508515353!GO:0046966;thyroid hormone receptor binding;0.00622631233800574!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.00676837240016473!GO:0048487;beta-tubulin binding;0.00679456202889818!GO:0004185;serine carboxypeptidase activity;0.0070202317400696!GO:0004004;ATP-dependent RNA helicase activity;0.00737903441989732!GO:0004860;protein kinase inhibitor activity;0.00759482246808727!GO:0030658;transport vesicle membrane;0.00759482246808727!GO:0006084;acetyl-CoA metabolic process;0.0076367157696866!GO:0002573;myeloid leukocyte differentiation;0.00771510993872469!GO:0051347;positive regulation of transferase activity;0.00774683816582646!GO:0016363;nuclear matrix;0.00783044662603445!GO:0019377;glycolipid catabolic process;0.00801665550416375!GO:0051348;negative regulation of transferase activity;0.00801928518744932!GO:0019220;regulation of phosphate metabolic process;0.00820289396513794!GO:0051174;regulation of phosphorus metabolic process;0.00820289396513794!GO:0043021;ribonucleoprotein binding;0.00876672242443232!GO:0030521;androgen receptor signaling pathway;0.00879600588882814!GO:0019210;kinase inhibitor activity;0.00893553613244828!GO:0016779;nucleotidyltransferase activity;0.00896968252261507!GO:0009109;coenzyme catabolic process;0.00965494340815635!GO:0050851;antigen receptor-mediated signaling pathway;0.00970285527345566!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.00981829701511219!GO:0005484;SNAP receptor activity;0.00985919035006539!GO:0000082;G1/S transition of mitotic cell cycle;0.00988945551922521!GO:0042107;cytokine metabolic process;0.00990350119808961!GO:0051098;regulation of binding;0.010005100452121!GO:0051252;regulation of RNA metabolic process;0.0100153089681065!GO:0002250;adaptive immune response;0.0100184758130989!GO:0002460;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0100184758130989!GO:0030041;actin filament polymerization;0.0101305119545721!GO:0033549;MAP kinase phosphatase activity;0.0101337456396814!GO:0017017;MAP kinase tyrosine/serine/threonine phosphatase activity;0.0101337456396814!GO:0031072;heat shock protein binding;0.0102767867970808!GO:0006458;'de novo' protein folding;0.010572690249755!GO:0051084;'de novo' posttranslational protein folding;0.010572690249755!GO:0030127;COPII vesicle coat;0.010572690249755!GO:0012507;ER to Golgi transport vesicle membrane;0.010572690249755!GO:0019867;outer membrane;0.010572690249755!GO:0006352;transcription initiation;0.010572690249755!GO:0033367;protein localization in mast cell secretory granule;0.010572690249755!GO:0033365;protein localization in organelle;0.010572690249755!GO:0033371;T cell secretory granule organization and biogenesis;0.010572690249755!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.010572690249755!GO:0033375;protease localization in T cell secretory granule;0.010572690249755!GO:0042629;mast cell granule;0.010572690249755!GO:0033377;maintenance of protein localization in T cell secretory granule;0.010572690249755!GO:0033364;mast cell secretory granule organization and biogenesis;0.010572690249755!GO:0033380;granzyme B localization in T cell secretory granule;0.010572690249755!GO:0033379;maintenance of protease localization in T cell secretory granule;0.010572690249755!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.010572690249755!GO:0033368;protease localization in mast cell secretory granule;0.010572690249755!GO:0033366;protein localization in secretory granule;0.010572690249755!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.010572690249755!GO:0033374;protein localization in T cell secretory granule;0.010572690249755!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;0.0110357120389327!GO:0004812;aminoacyl-tRNA ligase activity;0.0110357120389327!GO:0016875;ligase activity, forming carbon-oxygen bonds;0.0110357120389327!GO:0005813;centrosome;0.0110460652501268!GO:0031968;organelle outer membrane;0.0112095636880822!GO:0030217;T cell differentiation;0.0112826431623806!GO:0051091;positive regulation of transcription factor activity;0.0113249377945896!GO:0008139;nuclear localization sequence binding;0.0114599838917479!GO:0009165;nucleotide biosynthetic process;0.0115919499769247!GO:0006607;NLS-bearing substrate import into nucleus;0.0118406393382556!GO:0030134;ER to Golgi transport vesicle;0.0119310201341995!GO:0030176;integral to endoplasmic reticulum membrane;0.0124222442851324!GO:0002237;response to molecule of bacterial origin;0.012784035648817!GO:0030867;rough endoplasmic reticulum membrane;0.0131712009102171!GO:0005152;interleukin-1 receptor antagonist activity;0.0131712009102171!GO:0030353;fibroblast growth factor receptor antagonist activity;0.0131712009102171!GO:0002684;positive regulation of immune system process;0.0134424497630356!GO:0007165;signal transduction;0.0143407656686302!GO:0042089;cytokine biosynthetic process;0.0144434558549242!GO:0019079;viral genome replication;0.0144497138146377!GO:0031625;ubiquitin protein ligase binding;0.0145030953445693!GO:0005048;signal sequence binding;0.0146198567430993!GO:0030518;steroid hormone receptor signaling pathway;0.0148309772238735!GO:0015631;tubulin binding;0.0148647479915354!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.015082534030637!GO:0043038;amino acid activation;0.0153573577049687!GO:0006418;tRNA aminoacylation for protein translation;0.0153573577049687!GO:0043039;tRNA aminoacylation;0.0153573577049687!GO:0030098;lymphocyte differentiation;0.0155004193667188!GO:0046466;membrane lipid catabolic process;0.0158041337678465!GO:0016791;phosphoric monoester hydrolase activity;0.0161038063159104!GO:0003690;double-stranded DNA binding;0.0161987138366478!GO:0045727;positive regulation of translation;0.0165007555235762!GO:0008624;induction of apoptosis by extracellular signals;0.0165726328276093!GO:0045089;positive regulation of innate immune response;0.0165726328276093!GO:0045088;regulation of innate immune response;0.0165726328276093!GO:0033674;positive regulation of kinase activity;0.017009806700425!GO:0030660;Golgi-associated vesicle membrane;0.0170736787873375!GO:0045944;positive regulation of transcription from RNA polymerase II promoter;0.0170825313518795!GO:0051101;regulation of DNA binding;0.0170849159763299!GO:0051051;negative regulation of transport;0.0171608084675972!GO:0000209;protein polyubiquitination;0.017188318125887!GO:0046479;glycosphingolipid catabolic process;0.0176132959683163!GO:0050778;positive regulation of immune response;0.0178572787097337!GO:0048002;antigen processing and presentation of peptide antigen;0.0178572787097337!GO:0008637;apoptotic mitochondrial changes;0.01807980979756!GO:0003702;RNA polymerase II transcription factor activity;0.0181151547400278!GO:0043621;protein self-association;0.0181862404311597!GO:0002263;cell activation during immune response;0.0181862404311597!GO:0042093;T-helper cell differentiation;0.0181862404311597!GO:0002366;leukocyte activation during immune response;0.0181862404311597!GO:0002293;alpha-beta T cell differentiation during immune response;0.0181862404311597!GO:0002294;CD4-positive, alpha-beta T cell differentiation during immune response;0.0181862404311597!GO:0002285;lymphocyte activation during immune response;0.0181862404311597!GO:0002292;T cell differentiation during immune response;0.0181862404311597!GO:0002286;T cell activation during immune response;0.0181862404311597!GO:0002682;regulation of immune system process;0.0183290579317434!GO:0042035;regulation of cytokine biosynthetic process;0.0184502192918338!GO:0019883;antigen processing and presentation of endogenous antigen;0.0184979291887824!GO:0019955;cytokine binding;0.0185055185872874!GO:0050900;leukocyte migration;0.0187020626796593!GO:0009891;positive regulation of biosynthetic process;0.0191874670742864!GO:0044255;cellular lipid metabolic process;0.0192588064444306!GO:0006914;autophagy;0.0193297669194301!GO:0032763;regulation of mast cell cytokine production;0.0196071930761776!GO:0032762;mast cell cytokine production;0.0196071930761776!GO:0050811;GABA receptor binding;0.0197426932761891!GO:0051049;regulation of transport;0.0200238325605183!GO:0048500;signal recognition particle;0.0200775877827098!GO:0006333;chromatin assembly or disassembly;0.0210457293676222!GO:0002467;germinal center formation;0.0211575124107486!GO:0006399;tRNA metabolic process;0.0211894340213491!GO:0006650;glycerophospholipid metabolic process;0.0213730528525738!GO:0045746;negative regulation of Notch signaling pathway;0.0214283360438233!GO:0008333;endosome to lysosome transport;0.0214283360438233!GO:0042348;NF-kappaB import into nucleus;0.0214283360438233!GO:0042345;regulation of NF-kappaB import into nucleus;0.0214283360438233!GO:0045639;positive regulation of myeloid cell differentiation;0.0216097849602257!GO:0042611;MHC protein complex;0.0219363415759962!GO:0019058;viral infectious cycle;0.022241999163193!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.0222487974666841!GO:0006644;phospholipid metabolic process;0.0224644837754074!GO:0002822;regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.;0.0224644837754074!GO:0002819;regulation of adaptive immune response;0.0224644837754074!GO:0046467;membrane lipid biosynthetic process;0.0225090094563747!GO:0002697;regulation of immune effector process;0.0227157913273481!GO:0006968;cellular defense response;0.0227264728915566!GO:0031327;negative regulation of cellular biosynthetic process;0.0235919072906065!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0236066686569285!GO:0043022;ribosome binding;0.0236066686569285!GO:0001562;response to protozoan;0.0236066686569285!GO:0002440;production of molecular mediator of immune response;0.023709458323111!GO:0005815;microtubule organizing center;0.0238385300085978!GO:0002224;toll-like receptor signaling pathway;0.0239091309447352!GO:0002221;pattern recognition receptor signaling pathway;0.0239091309447352!GO:0043488;regulation of mRNA stability;0.0239091309447352!GO:0043487;regulation of RNA stability;0.0239091309447352!GO:0045860;positive regulation of protein kinase activity;0.0241255975972694!GO:0019965;interleukin binding;0.0243045499825269!GO:0030027;lamellipodium;0.0243261547074363!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.024606914633681!GO:0000278;mitotic cell cycle;0.0247261622734437!GO:0003725;double-stranded RNA binding;0.024897942558774!GO:0008361;regulation of cell size;0.0251228180893611!GO:0008283;cell proliferation;0.0252390795212062!GO:0030503;regulation of cell redox homeostasis;0.0255591912282811!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0255859915718592!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0255859915718592!GO:0046631;alpha-beta T cell activation;0.0255969441157608!GO:0009890;negative regulation of biosynthetic process;0.0255969441157608!GO:0042325;regulation of phosphorylation;0.0261054438185014!GO:0005149;interleukin-1 receptor binding;0.0261988099606103!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0263940938664279!GO:0045047;protein targeting to ER;0.0263940938664279!GO:0030133;transport vesicle;0.0265879442613856!GO:0051085;chaperone cofactor-dependent protein folding;0.0268292120829128!GO:0048872;homeostasis of number of cells;0.027442237334322!GO:0051329;interphase of mitotic cell cycle;0.027442237334322!GO:0017091;AU-rich element binding;0.027442237334322!GO:0050779;RNA destabilization;0.027442237334322!GO:0000289;poly(A) tail shortening;0.027442237334322!GO:0002444;myeloid leukocyte mediated immunity;0.0275440299917776!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0281765485585082!GO:0030663;COPI coated vesicle membrane;0.0283179944652387!GO:0030126;COPI vesicle coat;0.0283179944652387!GO:0048146;positive regulation of fibroblast proliferation;0.0283243262456632!GO:0019318;hexose metabolic process;0.0286606539731589!GO:0004702;receptor signaling protein serine/threonine kinase activity;0.0286606539731589!GO:0006414;translational elongation;0.0288528667302489!GO:0000785;chromatin;0.0289127661527919!GO:0008656;caspase activator activity;0.0291107655169275!GO:0045936;negative regulation of phosphate metabolic process;0.0291107655169275!GO:0042613;MHC class II protein complex;0.0291107655169275!GO:0045792;negative regulation of cell size;0.0291107655169275!GO:0015923;mannosidase activity;0.0291472188112549!GO:0000339;RNA cap binding;0.0291472188112549!GO:0035035;histone acetyltransferase binding;0.0292518611259747!GO:0030377;U-plasminogen activator receptor activity;0.0292518611259747!GO:0030118;clathrin coat;0.0298604432417017!GO:0005905;coated pit;0.02990063214484!GO:0005869;dynactin complex;0.0299616765474701!GO:0002443;leukocyte mediated immunity;0.0300256908730004!GO:0043407;negative regulation of MAP kinase activity;0.0300256908730004!GO:0004177;aminopeptidase activity;0.0300375232020946!GO:0009306;protein secretion;0.0306574324027749!GO:0042092;T-helper 2 type immune response;0.0307530387015486!GO:0000287;magnesium ion binding;0.0307530387015486!GO:0019371;cyclooxygenase pathway;0.0311623911946233!GO:0042832;defense response to protozoan;0.0314903637111635!GO:0005996;monosaccharide metabolic process;0.0316051215130257!GO:0048471;perinuclear region of cytoplasm;0.0316887390520797!GO:0042088;T-helper 1 type immune response;0.0320331722962376!GO:0032318;regulation of Ras GTPase activity;0.0322991678384563!GO:0006749;glutathione metabolic process;0.0324229672130567!GO:0043405;regulation of MAP kinase activity;0.0324522853538736!GO:0006007;glucose catabolic process;0.0326489737449027!GO:0032760;positive regulation of tumor necrosis factor production;0.032951399591571!GO:0030308;negative regulation of cell growth;0.032951399591571!GO:0030384;phosphoinositide metabolic process;0.0330559814632189!GO:0051045;negative regulation of membrane protein ectodomain proteolysis;0.0330740667022231!GO:0051043;regulation of membrane protein ectodomain proteolysis;0.0330740667022231!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0336869626590282!GO:0017166;vinculin binding;0.0339439982283059!GO:0050727;regulation of inflammatory response;0.0339439982283059!GO:0031347;regulation of defense response;0.0339439982283059!GO:0030137;COPI-coated vesicle;0.0343461728563903!GO:0042992;negative regulation of transcription factor import into nucleus;0.0356957867515703!GO:0042308;negative regulation of protein import into nucleus;0.0356957867515703!GO:0050776;regulation of immune response;0.0358765132692965!GO:0009605;response to external stimulus;0.036179615783775!GO:0051052;regulation of DNA metabolic process;0.0362082480620009!GO:0051325;interphase;0.0366185150598736!GO:0045603;positive regulation of endothelial cell differentiation;0.0370136864105818!GO:0006979;response to oxidative stress;0.0377520012103288!GO:0016605;PML body;0.0377740430363054!GO:0051020;GTPase binding;0.0383269016367202!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.0383352441271989!GO:0043300;regulation of leukocyte degranulation;0.0384398136753307!GO:0042326;negative regulation of phosphorylation;0.0384968693129409!GO:0048144;fibroblast proliferation;0.0386697653464313!GO:0048145;regulation of fibroblast proliferation;0.0386697653464313!GO:0005350;pyrimidine transmembrane transporter activity;0.0386697653464313!GO:0015855;pyrimidine transport;0.0386697653464313!GO:0015288;porin activity;0.0386697653464313!GO:0003727;single-stranded RNA binding;0.0388056822873455!GO:0006350;transcription;0.0390813664200152!GO:0051050;positive regulation of transport;0.0390813664200152!GO:0050681;androgen receptor binding;0.0390813664200152!GO:0045576;mast cell activation;0.0390813664200152!GO:0006509;membrane protein ectodomain proteolysis;0.0390813664200152!GO:0033619;membrane protein proteolysis;0.0390813664200152!GO:0033033;negative regulation of myeloid cell apoptosis;0.0390813664200152!GO:0001803;regulation of type III hypersensitivity;0.0390813664200152!GO:0032733;positive regulation of interleukin-10 production;0.0390813664200152!GO:0033025;regulation of mast cell apoptosis;0.0390813664200152!GO:0001805;positive regulation of type III hypersensitivity;0.0390813664200152!GO:0033023;mast cell homeostasis;0.0390813664200152!GO:0002431;Fc receptor mediated stimulatory signaling pathway;0.0390813664200152!GO:0033032;regulation of myeloid cell apoptosis;0.0390813664200152!GO:0001802;type III hypersensitivity;0.0390813664200152!GO:0033028;myeloid cell apoptosis;0.0390813664200152!GO:0042590;antigen processing and presentation of exogenous peptide antigen via MHC class I;0.0390813664200152!GO:0033026;negative regulation of mast cell apoptosis;0.0390813664200152!GO:0033024;mast cell apoptosis;0.0390813664200152!GO:0006984;ER-nuclear signaling pathway;0.0396882795474763!GO:0005788;endoplasmic reticulum lumen;0.0397038584433338!GO:0004907;interleukin receptor activity;0.0401551581845238!GO:0042113;B cell activation;0.0405835772067999!GO:0008312;7S RNA binding;0.0407412175152951!GO:0032943;mononuclear cell proliferation;0.0408286924174844!GO:0046651;lymphocyte proliferation;0.0408286924174844!GO:0006595;polyamine metabolic process;0.0408589281880003!GO:0008286;insulin receptor signaling pathway;0.0411323929028278!GO:0004704;NF-kappaB-inducing kinase activity;0.041932466290975!GO:0004672;protein kinase activity;0.0419689269297951!GO:0008017;microtubule binding;0.0423294359329315!GO:0030155;regulation of cell adhesion;0.0424951632644712!GO:0051235;maintenance of localization;0.0424951632644712!GO:0043071;positive regulation of non-apoptotic programmed cell death;0.0426916404837868!GO:0030693;caspase activity;0.0428719061595232!GO:0016072;rRNA metabolic process;0.0428719061595232!GO:0030522;intracellular receptor-mediated signaling pathway;0.043088681984641!GO:0046823;negative regulation of nucleocytoplasmic transport;0.0432004173928118!GO:0031098;stress-activated protein kinase signaling pathway;0.0436342020401997!GO:0006405;RNA export from nucleus;0.0436342020401997!GO:0016505;apoptotic protease activator activity;0.0439232932939174!GO:0008287;protein serine/threonine phosphatase complex;0.0442524975446588!GO:0008154;actin polymerization and/or depolymerization;0.0442884034759393!GO:0015036;disulfide oxidoreductase activity;0.0443095662806681!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0445017564294023!GO:0016049;cell growth;0.0451981361394935!GO:0006364;rRNA processing;0.0453004821599428!GO:0051920;peroxiredoxin activity;0.0453004821599428!GO:0030258;lipid modification;0.0457088535463974!GO:0046426;negative regulation of JAK-STAT cascade;0.0457248083746007!GO:0000060;protein import into nucleus, translocation;0.0459575000094077!GO:0005669;transcription factor TFIID complex;0.0463609188228914!GO:0005100;Rho GTPase activator activity;0.0470390206790633!GO:0046474;glycerophospholipid biosynthetic process;0.0470390206790633!GO:0035258;steroid hormone receptor binding;0.047383923061144!GO:0001776;leukocyte homeostasis;0.0476437238020887!GO:0046632;alpha-beta T cell differentiation;0.047667772625102!GO:0006376;mRNA splice site selection;0.0477431703948625!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0477431703948625!GO:0046489;phosphoinositide biosynthetic process;0.0485926370541257!GO:0007006;mitochondrial membrane organization and biogenesis;0.0493735665387703!GO:0048660;regulation of smooth muscle cell proliferation;0.0497114199130739!GO:0030433;ER-associated protein catabolic process;0.0497906849360263!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0497906849360263 | |||
|sample_id=11864 | |||
|sample_note= | |||
|sample_sex=female | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue= | |||
|top_motifs=FOS_FOS{B,L1}_JUN{B,D}:6.52662133855;BACH2:6.2801498846;FOSL2:6.25186733072;NFE2:5.99051151103;HLF:5.93374894033;CEBPA,B_DDIT3:5.50979281599;IRF7:5.27619717537;NFIL3:5.0132627994;IRF1,2:4.94432627653;NFE2L2:4.79347267943;NFKB1_REL_RELA:4.71834689462;PAX2:4.29615829633;FOXP3:4.0517634868;SPIB:4.0260214973;NANOG{mouse}:3.9502568968;PAX8:3.82774561065;NFATC1..3:3.59388884235;NFE2L1:3.53600885156;SPI1:3.5334890953;DMAP1_NCOR{1,2}_SMARC:3.45577303026;NR1H4:3.45059235448;ATF5_CREB3:3.3714282685;STAT5{A,B}:3.27917511649;ETS1,2:3.15123324542;ATF4:3.11746544653;JUN:2.88575817805;SREBF1,2:2.83168090553;RUNX1..3:2.70257374721;ATF6:2.69450705122;PAX3,7:2.59257421266;CDX1,2,4:2.51039214905;CREB1:2.46834450819;MAFB:2.44287525728;ATF2:2.24129141417;HSF1,2:2.18399664378;STAT2,4,6:2.0722643325;HOX{A5,B5}:1.94526297564;XBP1:1.89670057946;FOXN1:1.7875022786;FOXO1,3,4:1.74482820386;HMGA1,2:1.70097966908;RXRA_VDR{dimer}:1.62083572588;PAX1,9:1.51267036318;ALX4:1.34389304002;IKZF1:1.30455346732;ELF1,2,4:1.11468787333;PPARG:1.07840069648;PRDM1:1.02974640053;TGIF1:1.00477030726;EP300:0.973038432294;BPTF:0.916000097269;SRF:0.680611933737;HOXA9_MEIS1:0.641906588691;ZBTB16:0.474409992961;HIF1A:0.455618604524;DBP:0.435123514669;EN1,2:0.382223278994;NR3C1:0.373644763107;PAX4:0.217746292038;HMX1:0.12904419669;TBP:0.0917383472116;GLI1..3:0.0667232472703;PDX1:0.0537738718368;PITX1..3:-0.0668923162374;POU2F1..3:-0.0946850823243;OCT4_SOX2{dimer}:-0.122989797868;ESR1:-0.149630866513;IKZF2:-0.157987294561;NR6A1:-0.171540320764;RFX2..5_RFXANK_RFXAP:-0.260330442713;GATA4:-0.266318641736;SMAD1..7,9:-0.301941847876;FOXM1:-0.305961272662;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.331983134732;HBP1_HMGB_SSRP1_UBTF:-0.375587330125;TFCP2:-0.424675472497;RORA:-0.438650135528;MEF2{A,B,C,D}:-0.47740352187;TLX2:-0.484428548558;FOXL1:-0.498060295011;NANOG:-0.518444431804;MYB:-0.533165578976;EGR1..3:-0.613795548539;NKX3-1:-0.637911181122;POU5F1:-0.652341759208;SPZ1:-0.708225472035;FOXD3:-0.880040324539;T:-0.910418551831;SOX2:-0.917239450919;FOX{D1,D2}:-0.961553809778;AHR_ARNT_ARNT2:-0.969593272202;ESRRA:-0.983130073873;STAT1,3:-1.02471417624;POU3F1..4:-1.06719415153;RBPJ:-1.10708802698;TFAP4:-1.14136281199;HES1:-1.16746152966;RXR{A,B,G}:-1.17592686713;FOXP1:-1.18091586467;MZF1:-1.18119446065;VSX1,2:-1.23573201985;TAL1_TCF{3,4,12}:-1.36847252126;TEF:-1.38931748364;NFIX:-1.40952847436;ALX1:-1.43391287984;NKX2-2,8:-1.46257422523;MED-1{core}:-1.46444487815;POU6F1:-1.47400239327;ADNP_IRX_SIX_ZHX:-1.54392906137;NHLH1,2:-1.57302387966;HNF1A:-1.57336080321;ZNF384:-1.58442022945;ZBTB6:-1.59562768486;ZNF238:-1.59764409758;PRRX1,2:-1.6276950419;HNF4A_NR2F1,2:-1.64792138621;MYFfamily:-1.72827708788;AIRE:-1.72946390814;NKX2-1,4:-1.74164502659;E2F1..5:-1.78153404813;TEAD1:-1.78990294791;PAX6:-1.79309579178;CDC5L:-1.79853695774;HOX{A4,D4}:-1.80099542368;ARID5B:-1.86021690073;GTF2A1,2:-1.8676411418;REST:-1.89207296125;MTE{core}:-1.90500750907;GCM1,2:-1.92190486128;SOX5:-1.9756983215;ZFP161:-1.99002719148;BREu{core}:-2.00404691406;TBX4,5:-2.00794882869;GZF1:-2.0507162337;RXR{A,B,G}_{NR1H2,PPAR}dimers:-2.06662203889;FOX{F1,F2,J1}:-2.09234709084;TFDP1:-2.09326390302;PATZ1:-2.12398923223;GTF2I:-2.14304849364;CUX2:-2.14953705861;TFAP2B:-2.15539402526;NKX6-1,2:-2.15765434324;TP53:-2.17393786013;CRX:-2.18696088347;ZIC1..3:-2.21466236345;NKX3-2:-2.240529369;TLX1..3_NFIC{dimer}:-2.24622235755;SP1:-2.28065044298;MAZ:-2.28541295219;RFX1:-2.29028565869;GATA6:-2.297719856;SOX{8,9,10}:-2.30177341231;RREB1:-2.32157353899;MYBL2:-2.43487815952;NKX2-3_NKX2-5:-2.4712542432;UFEwm:-2.5011209282;MTF1:-2.50849597114;EVI1:-2.62968738466;ZEB1:-2.66896424958;XCPE1{core}:-2.67306598291;TFAP2{A,C}:-2.6739916399;HOX{A6,A7,B6,B7}:-2.68509102159;ONECUT1,2:-2.70956217146;HIC1:-2.73185236469;FOXA2:-2.73213323757;GFI1B:-2.74863150529;SNAI1..3:-2.81965497476;KLF4:-2.84871006313;ELK1,4_GABP{A,B1}:-2.87119500396;SOX17:-2.89240740981;ZNF148:-2.91427944869;EBF1:-2.93298345543;ZNF423:-2.95789165116;FOX{I1,J2}:-2.96715658829;POU1F1:-3.07982159448;NFY{A,B,C}:-3.16602216308;NR5A1,2:-3.3802136689;AR:-3.42336809976;PBX1:-3.43067611155;FOXQ1:-3.44736697841;PAX5:-3.49648223519;LMO2:-3.68714223227;GFI1:-3.75070072357;TOPORS:-3.81500786342;bHLH_family:-3.81899608495;NRF1:-3.87521318042;MYOD1:-3.88513415804;LEF1_TCF7_TCF7L1,2:-3.96518739265;YY1:-4.15129292152;LHX3,4:-4.27719995553;HAND1,2:-4.32310585094;ZNF143:-4.71551979531 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11864-125B1;search_select_hide=table117:FF:11864-125B1 | |||
}} | }} |
Latest revision as of 18:24, 4 June 2020
Name: | CD14+ monocytes - treated with Group A streptococci, donor1 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13469 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13469
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13469
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.094 |
10 | 10 | 0.0233 |
100 | 100 | 0.988 |
101 | 101 | 0.793 |
102 | 102 | 0.914 |
103 | 103 | 0.253 |
104 | 104 | 0.523 |
105 | 105 | 0.128 |
106 | 106 | 9.54512e-4 |
107 | 107 | 0.178 |
108 | 108 | 0.678 |
109 | 109 | 0.332 |
11 | 11 | 0.127 |
110 | 110 | 0.181 |
111 | 111 | 0.0625 |
112 | 112 | 0.296 |
113 | 113 | 0.473 |
114 | 114 | 0.0208 |
115 | 115 | 0.28 |
116 | 116 | 0.86 |
117 | 117 | 0.0709 |
118 | 118 | 0.176 |
119 | 119 | 0.143 |
12 | 12 | 0.356 |
120 | 120 | 0.77 |
121 | 121 | 0.618 |
122 | 122 | 0.709 |
123 | 123 | 0.304 |
124 | 124 | 0.503 |
125 | 125 | 0.199 |
126 | 126 | 0.255 |
127 | 127 | 0.513 |
128 | 128 | 0.0463 |
129 | 129 | 0.329 |
13 | 13 | 0.098 |
130 | 130 | 0.258 |
131 | 131 | 0.902 |
132 | 132 | 0.0933 |
133 | 133 | 0.496 |
134 | 134 | 0.436 |
135 | 135 | 0.928 |
136 | 136 | 0.879 |
137 | 137 | 0.0512 |
138 | 138 | 0.349 |
139 | 139 | 0.0611 |
14 | 14 | 0.534 |
140 | 140 | 0.49 |
141 | 141 | 0.277 |
142 | 142 | 0.031 |
143 | 143 | 0.0179 |
144 | 144 | 0.508 |
145 | 145 | 0.256 |
146 | 146 | 0.827 |
147 | 147 | 0.894 |
148 | 148 | 0.0138 |
149 | 149 | 0.858 |
15 | 15 | 0.146 |
150 | 150 | 0.375 |
151 | 151 | 0.397 |
152 | 152 | 0.327 |
153 | 153 | 0.549 |
154 | 154 | 0.694 |
155 | 155 | 0.889 |
156 | 156 | 0.947 |
157 | 157 | 0.521 |
158 | 158 | 0.0697 |
159 | 159 | 0.16 |
16 | 16 | 0.318 |
160 | 160 | 0.35 |
161 | 161 | 0.428 |
162 | 162 | 0.275 |
163 | 163 | 0.0981 |
164 | 164 | 0.0918 |
165 | 165 | 0.292 |
166 | 166 | 0.778 |
167 | 167 | 0.25 |
168 | 168 | 0.174 |
169 | 169 | 0.0125 |
17 | 17 | 0.22 |
18 | 18 | 0.0818 |
19 | 19 | 0.448 |
2 | 2 | 0.53 |
20 | 20 | 0.167 |
21 | 21 | 0.756 |
22 | 22 | 0.334 |
23 | 23 | 0.0322 |
24 | 24 | 0.482 |
25 | 25 | 0.531 |
26 | 26 | 0.0465 |
27 | 27 | 0.521 |
28 | 28 | 0.41 |
29 | 29 | 0.244 |
3 | 3 | 0.111 |
30 | 30 | 0.407 |
31 | 31 | 0.756 |
32 | 32 | 0.642 |
33 | 33 | 0.251 |
34 | 34 | 0.776 |
35 | 35 | 0.108 |
36 | 36 | 0.0526 |
37 | 37 | 0.0786 |
38 | 38 | 0.362 |
39 | 39 | 0.745 |
4 | 4 | 0.833 |
40 | 40 | 0.18 |
41 | 41 | 0.0252 |
42 | 42 | 0.332 |
43 | 43 | 0.0208 |
44 | 44 | 0.634 |
45 | 45 | 0.836 |
46 | 46 | 0.17 |
47 | 47 | 0.478 |
48 | 48 | 0.451 |
49 | 49 | 0.116 |
5 | 5 | 0.311 |
50 | 50 | 0.988 |
51 | 51 | 0.473 |
52 | 52 | 0.399 |
53 | 53 | 0.614 |
54 | 54 | 0.421 |
55 | 55 | 0.462 |
56 | 56 | 0.631 |
57 | 57 | 0.831 |
58 | 58 | 0.168 |
59 | 59 | 0.217 |
6 | 6 | 0.818 |
60 | 60 | 0.051 |
61 | 61 | 0.722 |
62 | 62 | 0.083 |
63 | 63 | 0.469 |
64 | 64 | 0.445 |
65 | 65 | 0.201 |
66 | 66 | 0.196 |
67 | 67 | 0.469 |
68 | 68 | 0.808 |
69 | 69 | 0.358 |
7 | 7 | 0.266 |
70 | 70 | 0.0523 |
71 | 71 | 0.0235 |
72 | 72 | 0.142 |
73 | 73 | 0.214 |
74 | 74 | 0.0318 |
75 | 75 | 0.129 |
76 | 76 | 0.148 |
77 | 77 | 0.502 |
78 | 78 | 0.0938 |
79 | 79 | 0.86 |
8 | 8 | 0.319 |
80 | 80 | 0.225 |
81 | 81 | 0.313 |
82 | 82 | 0.129 |
83 | 83 | 0.0306 |
84 | 84 | 0.0904 |
85 | 85 | 0.029 |
86 | 86 | 0.0825 |
87 | 87 | 0.537 |
88 | 88 | 0.803 |
89 | 89 | 0.213 |
9 | 9 | 0.323 |
90 | 90 | 0.102 |
91 | 91 | 0.392 |
92 | 92 | 0.278 |
93 | 93 | 0.527 |
94 | 94 | 0.0858 |
95 | 95 | 0.39 |
96 | 96 | 0.352 |
97 | 97 | 0.552 |
98 | 98 | 0.0996 |
99 | 99 | 0.0894 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13469
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0011106 human CD14-positive monocytes - treated with Group A streptococci sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000766 (myeloid leukocyte)
0000219 (motile cell)
0000325 (stuff accumulating cell)
0000473 (defensive cell)
0000234 (phagocyte)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0000255 (eukaryotic cell)
0000576 (monocyte)
0000860 (classical monocyte)
0002057 (CD14-positive, CD16-negative classical monocyte)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
0000625 (experimental infection sample)
0000350 (experimentally modified sample)
0000632 (group A streptococci treatment sample)
0011106 (human CD14-positive monocytes - treated with Group A streptococci sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)
CL:0002057 (CD14-positive, CD16-negative classical monocyte)