FF:11872-125B9: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005981 | ||
| | |accession_numbers=CAGE;DRX008157;DRR009029;DRZ000454;DRZ001839;DRZ011804;DRZ013189 | ||
| | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000766,CL:0000219,CL:0000325,CL:0000473,CL:0000234,CL:0000738,CL:0002087,CL:0000255,CL:0000576,CL:0000860,CL:0002057 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001,FF:0000625,FF:0000350,FF:0000631,FF:0011444 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr2:68592406..68592424,+!p1@PLEK!3.55!3564.34!PLEK;;chr16:85932760..85932775,+!p1@IRF8!3.08!1191.07!IRF8;;chr11:47400078..47400106,-!p1@SPI1!2.65!447.43!SPI1;;chr10:35484053..35484076,+!p1@CREM!2.58!912.07!CREM;;chr10:64576105..64576133,-!p1@EGR2!2.53!675.32!EGR2;;chr12:54778471..54778528,-!p1@ZNF385A!2.50!311.85!ZNF385A;;chr7:115670804..115670825,-!p1@TFEC!2.31!204.94!TFEC;;chr11:47399947..47399961,-!p3@SPI1!2.18!151.23!SPI1;;chr21:34442439..34442455,+!p1@OLIG1!2.17!147.06!OLIG1;;chr6:106534192..106534224,+!p1@PRDM1!2.09!331.66!PRDM1;;chr7:128577972..128578047,+!p1@IRF5!2.09!188.26!IRF5;;chr11:64764435..64764449,-!p1@BATF2!2.08!163.22!BATF2;;chr20:39317868..39317884,-!p1@MAFB!2.07!1293.80!MAFB;;chr6:36355431..36355466,-!p1@ETV7!2.02!103.78!ETV7;;chr21:36260295..36260310,-!p3@RUNX1!1.98!150.19!RUNX1;;chr17:45810594..45810608,+!p1@TBX21!1.95!87.61!TBX21;;chr5:131826457..131826514,-!p1@IRF1!1.94!3141.93!IRF1;;chr11:47400062..47400077,-!p2@SPI1!1.94!85.52!SPI1;;chr11:47399996..47400014,-!p4@SPI1!1.93!83.44!SPI1;;chr19:45971246..45971265,+!p1@FOSB!1.91!1393.92!FOSB;;chr10:35484090..35484104,+!p6@CREM!1.90!78.74!CREM;;chr16:31885093..31885165,+!p1@ZNF267!1.84!983.00!ZNF267;;chr19:33793430..33793447,-!p1@CEBPA!1.84!273.26!CEBPA;;chr6:106534230..106534254,+!p2@PRDM1!1.84!165.83!PRDM1;;chr1:25256756..25256774,-!p1@RUNX3!1.81!116.81!RUNX3;;chr10:64018918..64018936,+!p2@ZNF365!1.80!62.58!ZNF365;;chr2:68592394..68592405,+!p2@PLEK!1.80!61.53!PLEK;;chr1:221052776..221052799,+!p1@HLX!1.78!103.78!HLX;;chr16:79634624..79634642,-!p1@MAF!1.77!217.46!MAF;;chr19:50432132..50432217,+!p2@ATF5!1.75!65.19!ATF5;;chr12:72056800..72056834,+!p1@THAP2!1.73!69.88!THAP2;;chr2:97202480..97202499,+!p1@ARID5A!1.72!488.11!ARID5A;;chr2:70142232..70142251,+!p1@MXD1!1.72!273.78!MXD1;;chr11:615942..615957,-!p1@IRF7!1.71!454.73!IRF7;;chr9:102584159..102584174,+!p2@NR4A3!1.71!87.61!NR4A3;;chr11:47400032..47400043,-!p5@SPI1!1.71!50.58!SPI1;;chr10:31288398..31288455,-!p2@ZNF438!1.69!55.80!ZNF438;;chr8:22550982..22550999,-!p1@EGR3!1.68!126.72!EGR3;;chr12:54778351..54778378,-!p6@ZNF385A!1.68!46.93!ZNF385A;;chr1:221052733..221052749,+!p2@HLX!1.67!59.45!HLX;;chr12:72056749..72056767,+!p6@THAP2!1.67!50.58!THAP2;;chr6:391743..391759,+!p1@IRF4!1.66!44.33!IRF4;;chr2:157189180..157189290,-!p1@NR4A2!1.65!215.89!NR4A2;;chr11:65430554..65430579,-!p3@RELA!1.65!107.43!RELA;;chr19:45251395..45251432,+!p8@BCL3!1.64!42.76!BCL3;;chr1:158985493..158985535,+!p4@IFI16!1.63!62.06!IFI16;;chr22:38597987..38598021,+!p2@MAFF!1.61!230.50!MAFF;;chr1:212782094..212782109,+!p1@ATF3!1.60!1002.29!ATF3;;chr2:145277640..145277771,-!p1@ZEB2!1.60!495.93!ZEB2;;chr21:30671690..30671762,+!p2@BACH1!1.60!126.20!BACH1;;chr6:106535598..106535637,+!p7@PRDM1!1.60!38.59!PRDM1;;chr3:12329397..12329433,+!p2@PPARG!1.59!84.48!PPARG;;chr2:145275162..145275202,-!p2@ZEB2!1.58!208.07!ZEB2;;chr21:30671235..30671253,+!p1@BACH1!1.57!438.05!BACH1;;chr14:75988771..75988826,+!p1@BATF!1.56!46.41!BATF;;chr21:36421535..36421610,-!p2@RUNX1!1.55!119.42!RUNX1;;chr7:50344289..50344323,+!p1@IKZF1!1.54!33.90!IKZF1;;chr14:75988831..75988847,+!p2@BATF!1.54!33.37!BATF;;chr2:231084639..231084654,-!p2@SP110!1.53!53.71!SP110;;chr10:35484804..35484902,+!p2@CREM!1.51!116.81!CREM;;chr14:35872453..35872485,-!p2@NFKBIA!1.51!75.09!NFKBIA;;chr16:79634595..79634620,-!p2@MAF!1.51!55.80!MAF;;chr12:72056773..72056796,+!p3@THAP2!1.51!40.68!THAP2;;chr17:38497662..38497713,+!p4@RARA!1.51!35.98!RARA;;chr11:65430535..65430549,-!p4@RELA!1.49!34.94!RELA;;chrX:153305787..153305807,-!p3@MECP2!1.49!30.25!MECP2;;chr10:51572408..51572454,+!p3@NCOA4!1.48!165.31!NCOA4;;chr1:158979872..158979898,+!p3@IFI16!1.48!88.13!IFI16;;chr20:48807351..48807384,+!p1@CEBPB!1.47!2786.80!CEBPB;;chr21:34398234..34398250,+!p1@OLIG2!1.47!28.68!OLIG2;;chrX:129244454..129244488,-!p1@ELF4!1.46!193.47!ELF4;;chr9:102584128..102584144,+!p3@NR4A3!1.46!52.67!NR4A3;;chr10:31288370..31288393,-!p3@ZNF438!1.46!28.16!ZNF438;;chr19:19496539..19496576,+!p8@GATAD2A!1.44!45.37!GATAD2A;;chr4:185395590..185395627,-!p3@IRF2!1.44!32.85!IRF2;;chr21:36260343..36260402,-!p6@RUNX1!1.43!40.68!RUNX1;;chr6:144385698..144385742,-!p2@PLAGL1!1.43!31.29!PLAGL1;;chr2:231090471..231090504,+!p2@SP140!1.43!26.07!SP140;;chr11:47400045..47400060,-!p6@SPI1!1.43!26.07!SPI1;;chr13:41593425..41593480,-!p1@ELF1!1.42!154.36!ELF1;;chr6:15246200..15246214,+!p2@JARID2!1.42!68.31!JARID2;;chr18:3449720..3449749,+!p2@TGIF1!1.42!53.19!TGIF1;;chr12:48298765..48298783,-!p2@VDR!1.42!52.15!VDR;;chr9:110252035..110252057,-!p1@KLF4!1.41!380.16!KLF4;;chr3:39195139..39195150,-!p3@CSRNP1!1.40!30.77!CSRNP1;;chr11:47399920..47399931,-!p7@SPI1!1.40!23.99!SPI1;;chr11:615570..615721,-!p2@IRF7!1.39!45.37!IRF7;;chr2:191885737..191885750,-!p4@STAT1!1.38!22.95!STAT1;;chr4:185395633..185395651,-!p2@IRF2!1.37!35.46!IRF2;;chr1:25256439..25256476,-!p3@RUNX3!1.37!22.42!RUNX3;;chr19:36391434..36391450,-!p1@NFKBID!1.36!42.76!NFKBID;;chr9:129567282..129567353,+!p1@ZBTB43!1.35!274.30!ZBTB43;;chr2:61108695..61108753,+!p1@REL!1.35!141.84!REL;;chr12:52445218..52445237,+!p1@NR4A1!1.34!257.09!NR4A1;;chr12:11802753..11802834,+!p2@ETV6!1.34!100.12!ETV6;;chr20:48599506..48599526,+!p1@SNAI1!1.33!127.76!SNAI1;;chr9:102584262..102584276,+!p1@NR4A3!1.33!45.37!NR4A3;;chr20:48809000..48809053,+!p12@CEBPB!1.33!27.12!CEBPB;;chr19:54058073..54058088,+!p1@ZNF331!1.33!20.34!ZNF331;;chr22:38598086..38598105,+!p1@MAFF!1.31!199.21!MAFF;;chr3:187463179..187463201,-!p2@BCL6!1.31!78.22!BCL6;;chr19:45250948..45250998,+!p3@BCL3!1.31!48.50!BCL3;;chr16:79634581..79634592,-!p4@MAF!1.31!19.29!MAF;;chr7:150946376..150946389,-!p6@SMARCD3!1.30!18.77!SMARCD3;;chr14:35873947..35873965,-!p1@NFKBIA!1.29!1123.27!NFKBIA;;chr4:106068026..106068084,+!p1@TET2!1.29!163.22!TET2;;chr18:3449586..3449617,+!p8@TGIF1!1.29!29.20!TGIF1;;chr4:103422499..103422632,+!p1@NFKB1!1.27!359.82!NFKB1;;chr10:104155480..104155534,+!p2@NFKB2!1.27!111.08!NFKB2;;chr3:39195037..39195069,-!p2@CSRNP1!1.27!107.43!CSRNP1;;chr2:70167296..70167306,+!p3@MXD1!1.27!27.12!MXD1;;chr19:54041669..54041697,+!p2@ZNF331!1.27!17.73!ZNF331;;chr10:51572339..51572376,+!p4@NCOA4!1.26!38.07!NCOA4;;chr21:30672734..30672748,+!p11@BACH1!1.26!17.21!BACH1;;chr21:36260980..36261011,-!p1@RUNX1!1.25!466.73!RUNX1;;chr1:158979792..158979814,+!p2@IFI16!1.25!155.40!IFI16;;chr21:30672433..30672464,+!p6@BACH1!1.25!16.69!BACH1;;chr2:231090433..231090469,+!p1@SP140!1.25!16.69!SP140;;chr9:4300050..4300118,-!p1@GLIS3!1.24!103.78!GLIS3;;chr7:149470641..149470694,-!p1@ZNF467!1.24!73.01!ZNF467;;chr2:28618532..28618610,+!p4@FOSL2!1.24!28.16!FOSL2;;chr3:12330560..12330579,+!p1@PPARG!1.24!18.77!PPARG;;chr9:110250697..110250738,-!p2@KLF4!1.23!18.77!KLF4;;chr10:3827371..3827386,-!p2@KLF6!1.22!129.85!KLF6;;chr22:38598057..38598071,+!p3@MAFF!1.22!36.50!MAFF;;chr17:38497715..38497734,+!p8@RARA!1.22!15.64!RARA;;chr12:48298785..48298828,-!p1@VDR!1.21!79.79!VDR;;chr14:35872962..35873025,-!p3@NFKBIA!1.21!38.59!NFKBIA;;chr8:116681123..116681143,-!p4@TRPS1!1.21!29.20!TRPS1;;chr12:56415246..56415286,+!p2@IKZF4!1.21!15.12!IKZF4;;chr18:3449618..3449634,+!p13@TGIF1!1.20!18.25!TGIF1;;chr2:70314240..70314256,+!p4@PCBP1!1.19!29.72!PCBP1;;chr2:185463247..185463263,+!p1@ZNF804A!1.19!25.55!ZNF804A;;chr6:44233252..44233296,-!p1@NFKBIE!1.18!138.19!NFKBIE;;chr6:126240380..126240430,+!p2@NCOA7!1.18!36.50!NCOA7;;chr18:3449527..3449582,+!p6@TGIF1!1.18!27.12!TGIF1;;chr3:150126101..150126118,+!p6@TSC22D2!1.18!22.95!TSC22D2;;chrX:129244430..129244442,-!p5@ELF4!1.18!14.08!ELF4;;chr10:104154246..104154347,+!p3@NFKB2!1.17!83.96!NFKB2;;chr2:238600933..238600985,+!p3@LRRFIP1!1.17!75.09!LRRFIP1;;chr7:28725740..28725778,+!p1@CREB5!1.16!118.90!CREB5;;chr16:89787973..89788001,+!p3@ZNF276!1.16!25.55!ZNF276;;chr6:126240463..126240489,+!p6@NCOA7!1.16!15.12!NCOA7;;chr1:212738742..212738755,+!p2@ATF3!1.16!13.56!ATF3;;chr3:126191157..126191171,-!p4@ZXDC!1.16!13.56!ZXDC;;chr14:75745523..75745537,+!p1@FOS!1.15!1558.19!FOS;;chr20:48807456..48807475,+!p3@CEBPB!1.15!25.55!CEBPB;;chr11:65430038..65430053,-!p12@RELA!1.15!13.04!RELA;;chr2:28615716..28615733,+!p1@FOSL2!1.14!600.75!FOSL2;;chr1:935467..935484,-!p1@HES4!1.14!56.84!HES4;;chr16:3285119..3285133,-!p2@ZNF200!1.14!25.55!ZNF200;;chr5:142782823..142782854,-!p3@NR3C1!1.14!18.25!NR3C1;;chr2:231084820..231084836,-!p5@SP110!1.14!14.60!SP110;;chr17:38474489..38474548,+!p1@RARA!1.13!395.28!RARA;;chr14:74226747..74226779,-!p3@C14orf43!1.13!68.84!C14orf43;;chr10:64575812..64575824,-!p4@EGR2!1.13!12.52!EGR2;;chr13:41593392..41593403,-!p7@ELF1!1.13!12.52!ELF1;;chr7:17338266..17338282,+!p1@AHR!1.12!132.46!AHR;;chr19:45252008..45252024,+!p2@BCL3!1.12!40.15!BCL3;;chr18:3448455..3448480,+!p5@TGIF1!1.12!22.42!TGIF1;;chr6:15246217..15246228,+!p3@JARID2!1.12!21.38!JARID2;;chr20:48807615..48807644,+!p6@CEBPB!1.12!20.34!CEBPB;;chr1:221052994..221053008,+!p6@HLX!1.12!14.60!HLX;;chr21:40177845..40177863,+!p1@ETS2!1.11!708.17!ETS2;;chr21:36260463..36260480,-!p9@RUNX1!1.11!16.17!RUNX1;;chr1:158985686..158985719,+!p15@IFI16!1.11!11.99!IFI16;;chr21:36260325..36260341,-!p14@RUNX1!1.11!11.99!RUNX1;;chr4:106066712..106066728,+!p8@TET2!1.11!11.99!TET2;;chr2:231084659..231084721,-!p1@SP110!1.10!268.04!SP110;;chr2:238600998..238601013,+!p5@LRRFIP1!1.10!11.47!LRRFIP1;;chr2:68615063..68615089,+!p4@PLEK!1.10!11.47!PLEK;;chr3:187455680..187455700,-!p4@BCL6!1.10!11.47!BCL6;;chr1:158979922..158979933,+!p13@IFI16!1.10!11.47!IFI16;;chr2:145277882..145277967,-!p3@ZEB2!1.09!19.82!ZEB2;;chr16:3285144..3285191,-!p1@ZNF200!1.08!54.23!ZNF200;;chr1:221054853..221054873,+!p9@HLX!1.08!10.95!HLX;;chr7:137620684..137620711,-!p4@CREB3L2!1.08!10.95!CREB3L2;;chr2:145271342..145271377,-!p5@ZEB2!1.08!10.95!ZEB2;;chr1:37940170..37940190,+!p1@ZC3H12A!1.07!134.02!ZC3H12A;;chr2:208394817..208394834,+!p3@CREB1!1.07!43.28!CREB1;;chr10:35416142..35416169,+!p3@CREM!1.07!28.68!CREM;;chr2:145275228..145275241,-!p11@ZEB2!1.07!13.04!ZEB2;;chr10:104155455..104155479,+!p1@NFKB2!1.06!152.79!NFKB2;;chr1:157108130..157108173,-!p1@ETV3!1.06!77.18!ETV3;;chr6:35310395..35310410,+!p2@PPARD!1.06!41.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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000222;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000234;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000576;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000763;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000766;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000860;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002193;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002390;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002405 | |||
|ffid_belonging_in_development=CL:0000049,CL:0000134,CL:0002057 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 41: | ||
|fonse_treatment=EFO:0000369,FF:0000625,FF:0000631,FF:0011444,FF:11872-125B9 | |fonse_treatment=EFO:0000369,FF:0000625,FF:0000631,FF:0011444,FF:11872-125B9 | ||
|fonse_treatment_closure=EFO:0000369,FF:0000625,FF:0000631,FF:0011444,FF:11872-125B9 | |fonse_treatment_closure=EFO:0000369,FF:0000625,FF:0000631,FF:0011444,FF:11872-125B9 | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Trehalose%2520dimycolate%2520%2528TDM%2529%252c%2520donor2.CNhs13483.11872-125B9.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Trehalose%2520dimycolate%2520%2528TDM%2529%252c%2520donor2.CNhs13483.11872-125B9.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Trehalose%2520dimycolate%2520%2528TDM%2529%252c%2520donor2.CNhs13483.11872-125B9.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Trehalose%2520dimycolate%2520%2528TDM%2529%252c%2520donor2.CNhs13483.11872-125B9.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520Trehalose%2520dimycolate%2520%2528TDM%2529%252c%2520donor2.CNhs13483.11872-125B9.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11872-125B9 | |||
|is_a=EFO:0002091;;FF:0011444 | |||
|is_obsolete= | |||
|library_id=CNhs13483 | |||
|library_id_phase_based=2:CNhs13483 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11872 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11872 | |||
|name=CD14+ monocytes - treated with Trehalose dimycolate (TDM), donor2 | |||
|namespace= | |namespace= | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs13483,LSID1025,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
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| |||
|rna_box=125 | |||
|rna_catalog_number= | |||
|rna_concentration=0.61499 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number=D4-3 | |||
|rna_od260/230=1.47 | |||
|rna_od260/280=2.02 | |||
|rna_position=B9 | |||
|rna_rin=8.6 | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=125B9 | |||
|rna_weight_ug=2.767455 | |||
|sample_age=51 | |||
|sample_category=primary cells | |||
|sample_cell_catalog= | |||
|sample_cell_line= | |||
|sample_cell_lot= | |||
|sample_cell_type=monocyte | |||
|sample_collaboration=Christine Wells (University of Queensland) | |||
|sample_company= | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease= | |||
|sample_donor(cell lot)=donor2 | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.30130321511915e-279!GO:0005737;cytoplasm;3.35307488309146e-127!GO:0043227;membrane-bound organelle;2.62518320261348e-111!GO:0043231;intracellular membrane-bound organelle;5.44624555433085e-111!GO:0043226;organelle;1.47720311752011e-103!GO:0043229;intracellular organelle;9.41466341255468e-103!GO:0044444;cytoplasmic part;5.05810582512106e-84!GO:0005515;protein binding;5.51431873279e-71!GO:0044422;organelle part;1.29760291045621e-68!GO:0044446;intracellular organelle part;4.95033051216874e-67!GO:0044237;cellular metabolic process;7.77060301960438e-63!GO:0044238;primary metabolic process;2.5855905622805e-62!GO:0043170;macromolecule metabolic process;9.09102005407218e-60!GO:0032991;macromolecular complex;9.41216403276493e-57!GO:0003723;RNA binding;6.18057477467351e-55!GO:0030529;ribonucleoprotein complex;1.95622619041155e-49!GO:0019538;protein metabolic process;1.24053309183915e-48!GO:0044428;nuclear part;3.09299814687237e-46!GO:0044267;cellular protein metabolic process;9.25390111397418e-45!GO:0044260;cellular macromolecule metabolic process;1.49698570193369e-44!GO:0005634;nucleus;1.19172584614647e-43!GO:0033036;macromolecule localization;3.24700265516332e-40!GO:0015031;protein transport;2.14700019060508e-39!GO:0045184;establishment of protein localization;3.0659324984597e-39!GO:0006412;translation;8.27468559876391e-38!GO:0008104;protein localization;1.86522923507042e-37!GO:0005829;cytosol;3.33942662857614e-36!GO:0043233;organelle lumen;3.33942662857614e-36!GO:0031974;membrane-enclosed lumen;3.33942662857614e-36!GO:0031090;organelle membrane;1.76555857994662e-33!GO:0016071;mRNA metabolic process;4.91234157551581e-31!GO:0006915;apoptosis;2.67290191821988e-30!GO:0043283;biopolymer metabolic process;2.7427990543868e-30!GO:0012501;programmed cell death;3.26086549759602e-30!GO:0006396;RNA processing;2.25022610612128e-29!GO:0010467;gene expression;4.38808564769171e-29!GO:0008219;cell death;6.37667962523247e-29!GO:0016265;death;6.37667962523247e-29!GO:0043234;protein complex;1.52536920026232e-28!GO:0009059;macromolecule biosynthetic process;1.53803600518356e-28!GO:0016043;cellular component organization and biogenesis;2.10710219832532e-28!GO:0031981;nuclear lumen;5.39562174527507e-28!GO:0044249;cellular biosynthetic process;1.35220579204669e-27!GO:0009058;biosynthetic process;2.04664252050138e-27!GO:0008380;RNA splicing;2.44220265446509e-27!GO:0046907;intracellular transport;4.48662870356461e-27!GO:0006886;intracellular protein transport;1.57124170983092e-26!GO:0005739;mitochondrion;2.91325302399467e-26!GO:0006397;mRNA processing;3.49399119325688e-26!GO:0005840;ribosome;4.0929201011e-26!GO:0031967;organelle envelope;8.41986452896516e-26!GO:0031975;envelope;1.58000469562078e-25!GO:0003735;structural constituent of ribosome;6.48395521664386e-24!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.6802262124699e-23!GO:0033279;ribosomal subunit;5.67621817004577e-23!GO:0065003;macromolecular complex assembly;5.53794332698082e-22!GO:0044445;cytosolic part;3.8379735204659e-21!GO:0000166;nucleotide binding;4.57483833029559e-21!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;5.83850703239479e-21!GO:0051649;establishment of cellular localization;1.55459620661572e-20!GO:0042981;regulation of apoptosis;1.80869482455693e-20!GO:0008134;transcription factor binding;2.69469443076771e-20!GO:0005681;spliceosome;2.92285882155981e-20!GO:0043067;regulation of programmed cell death;4.33697223440619e-20!GO:0051641;cellular localization;6.42625781866731e-20!GO:0005654;nucleoplasm;1.10875199639706e-19!GO:0044429;mitochondrial part;3.58663608581269e-19!GO:0022607;cellular component assembly;5.94497998270804e-19!GO:0002376;immune system process;1.79531712248923e-18!GO:0007243;protein kinase cascade;1.22762820389293e-17!GO:0016192;vesicle-mediated transport;1.97787031991872e-17!GO:0048523;negative regulation of cellular process;2.77609778053019e-17!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;3.64920104359004e-17!GO:0016462;pyrophosphatase activity;3.76693414019388e-17!GO:0016817;hydrolase activity, acting on acid anhydrides;4.92145064963777e-17!GO:0044265;cellular macromolecule catabolic process;5.59731973915605e-17!GO:0022613;ribonucleoprotein complex biogenesis and assembly;6.18042140300811e-17!GO:0017111;nucleoside-triphosphatase activity;6.41758117976269e-17!GO:0048770;pigment granule;6.82804249157801e-17!GO:0042470;melanosome;6.82804249157801e-17!GO:0006119;oxidative phosphorylation;1.3944185110663e-16!GO:0044451;nucleoplasm part;1.79830445457867e-16!GO:0006512;ubiquitin cycle;3.81611061744966e-16!GO:0043285;biopolymer catabolic process;6.86652401412844e-16!GO:0005740;mitochondrial envelope;8.12032386540034e-16!GO:0043412;biopolymer modification;1.1688526092012e-15!GO:0032553;ribonucleotide binding;1.41685023795867e-15!GO:0032555;purine ribonucleotide binding;1.41685023795867e-15!GO:0007249;I-kappaB kinase/NF-kappaB cascade;1.45209662411782e-15!GO:0022618;protein-RNA complex assembly;2.54394799245055e-15!GO:0031966;mitochondrial membrane;2.81446857900073e-15!GO:0006955;immune response;3.08644267151102e-15!GO:0005773;vacuole;3.55845682026969e-15!GO:0048519;negative regulation of biological process;5.22206632878847e-15!GO:0017076;purine nucleotide binding;8.3087103775529e-15!GO:0006464;protein modification process;1.30775275450873e-14!GO:0019941;modification-dependent protein catabolic process;1.4838447487382e-14!GO:0043632;modification-dependent macromolecule catabolic process;1.4838447487382e-14!GO:0007242;intracellular signaling cascade;1.59590890591054e-14!GO:0044257;cellular protein catabolic process;2.03771890825878e-14!GO:0051603;proteolysis involved in cellular protein catabolic process;2.11052613017486e-14!GO:0009057;macromolecule catabolic process;2.30001946581439e-14!GO:0006511;ubiquitin-dependent protein catabolic process;2.86427211991729e-14!GO:0043687;post-translational protein modification;4.18530646947097e-14!GO:0019866;organelle inner membrane;5.09001991808551e-14!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;8.24594100820089e-14!GO:0006605;protein targeting;1.0462381671689e-13!GO:0000323;lytic vacuole;1.67593768074093e-13!GO:0005764;lysosome;1.67593768074093e-13!GO:0016604;nuclear body;2.17372973576714e-13!GO:0044248;cellular catabolic process;2.25375817957244e-13!GO:0012505;endomembrane system;2.55123875263635e-13!GO:0043069;negative regulation of programmed cell death;3.89004223221145e-13!GO:0043066;negative regulation of apoptosis;4.48725028936759e-13!GO:0050794;regulation of cellular process;4.75857357281581e-13!GO:0006996;organelle organization and biogenesis;5.59700140552633e-13!GO:0006913;nucleocytoplasmic transport;5.98123699567955e-13!GO:0065009;regulation of a molecular function;8.29637917432059e-13!GO:0030163;protein catabolic process;8.56641591945623e-13!GO:0051169;nuclear transport;1.13913056100126e-12!GO:0000502;proteasome complex (sensu Eukaryota);1.18838556384461e-12!GO:0006950;response to stress;1.23789238418543e-12!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.41308448807172e-12!GO:0015934;large ribosomal subunit;1.47862890520589e-12!GO:0003676;nucleic acid binding;2.77922154502024e-12!GO:0005768;endosome;2.96726034500874e-12!GO:0003712;transcription cofactor activity;3.74566625609371e-12!GO:0006366;transcription from RNA polymerase II promoter;3.74566625609371e-12!GO:0008135;translation factor activity, nucleic acid binding;3.98899797425363e-12!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;4.31030829645858e-12!GO:0005794;Golgi apparatus;4.60523751591687e-12!GO:0016070;RNA metabolic process;5.00998868975616e-12!GO:0051246;regulation of protein metabolic process;6.66302584841835e-12!GO:0016874;ligase activity;6.83763939807203e-12!GO:0006793;phosphorus metabolic process;9.22054168223253e-12!GO:0006796;phosphate metabolic process;9.22054168223253e-12!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.15837938214218e-11!GO:0006457;protein folding;1.36126527821771e-11!GO:0005743;mitochondrial inner membrane;2.24031752484549e-11!GO:0015935;small ribosomal subunit;2.31766954668633e-11!GO:0003743;translation initiation factor activity;2.33281932129488e-11!GO:0009615;response to virus;3.34416197369289e-11!GO:0006916;anti-apoptosis;4.24035848354584e-11!GO:0016607;nuclear speck;4.63903929973751e-11!GO:0044455;mitochondrial membrane part;5.81834252134458e-11!GO:0006413;translational initiation;5.97226757221867e-11!GO:0050789;regulation of biological process;9.83686432764753e-11!GO:0005524;ATP binding;1.0565386168981e-10!GO:0016310;phosphorylation;1.29769266034526e-10!GO:0032559;adenyl ribonucleotide binding;1.58323613018831e-10!GO:0016787;hydrolase activity;1.97143314868737e-10!GO:0005783;endoplasmic reticulum;2.84429450976679e-10!GO:0005635;nuclear envelope;3.21859571677756e-10!GO:0006446;regulation of translational initiation;3.21859571677756e-10!GO:0009967;positive regulation of signal transduction;3.35656633171156e-10!GO:0051186;cofactor metabolic process;3.47262699188884e-10!GO:0048522;positive regulation of cellular process;6.7746811085592e-10!GO:0030554;adenyl nucleotide binding;8.37253278565278e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.00763140252899e-09!GO:0065007;biological regulation;1.0326411718941e-09!GO:0048518;positive regulation of biological process;1.37188735965556e-09!GO:0031324;negative regulation of cellular metabolic process;1.41269177974206e-09!GO:0051082;unfolded protein binding;1.99925843308378e-09!GO:0006259;DNA metabolic process;2.15914041988587e-09!GO:0050790;regulation of catalytic activity;2.59121030124464e-09!GO:0015986;ATP synthesis coupled proton transport;3.36413526685547e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;3.36413526685547e-09!GO:0016564;transcription repressor activity;3.88385930292879e-09!GO:0006732;coenzyme metabolic process;3.93596941968925e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;4.43661227596503e-09!GO:0009056;catabolic process;4.6874015620423e-09!GO:0009607;response to biotic stimulus;4.97059342036102e-09!GO:0005746;mitochondrial respiratory chain;5.10601454492176e-09!GO:0005770;late endosome;5.3605145303238e-09!GO:0005730;nucleolus;6.06190676017731e-09!GO:0019829;cation-transporting ATPase activity;6.06190676017731e-09!GO:0000398;nuclear mRNA splicing, via spliceosome;6.74958560517872e-09!GO:0000375;RNA splicing, via transesterification reactions;6.74958560517872e-09!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;6.74958560517872e-09!GO:0008639;small protein conjugating enzyme activity;1.04304082761461e-08!GO:0019787;small conjugating protein ligase activity;1.29325631401905e-08!GO:0004842;ubiquitin-protein ligase activity;1.57018224797835e-08!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.58976954349629e-08!GO:0016887;ATPase activity;1.59682109776718e-08!GO:0017038;protein import;1.6607008635369e-08!GO:0050136;NADH dehydrogenase (quinone) activity;1.9546420626656e-08!GO:0003954;NADH dehydrogenase activity;1.9546420626656e-08!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.9546420626656e-08!GO:0007049;cell cycle;2.20100431302079e-08!GO:0003924;GTPase activity;2.33999738634988e-08!GO:0051170;nuclear import;2.34135559968485e-08!GO:0048193;Golgi vesicle transport;2.51327177307533e-08!GO:0006163;purine nucleotide metabolic process;2.90472360585257e-08!GO:0009892;negative regulation of metabolic process;2.95836773860249e-08!GO:0009150;purine ribonucleotide metabolic process;3.13924367366416e-08!GO:0043065;positive regulation of apoptosis;3.21679656377543e-08!GO:0042623;ATPase activity, coupled;3.39574244822021e-08!GO:0031965;nuclear membrane;4.01768079189795e-08!GO:0009152;purine ribonucleotide biosynthetic process;4.01768079189795e-08!GO:0006164;purine nucleotide biosynthetic process;4.01768079189795e-08!GO:0006606;protein import into nucleus;4.3612783728207e-08!GO:0006754;ATP biosynthetic process;4.37834465127853e-08!GO:0006753;nucleoside phosphate metabolic process;4.37834465127853e-08!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;4.59052415942039e-08!GO:0019899;enzyme binding;4.87262129442482e-08!GO:0043068;positive regulation of programmed cell death;5.21711265424474e-08!GO:0009259;ribonucleotide metabolic process;5.38865604915405e-08!GO:0006417;regulation of translation;5.73585623424745e-08!GO:0009966;regulation of signal transduction;5.83406597212086e-08!GO:0005525;GTP binding;6.17676759434493e-08!GO:0016481;negative regulation of transcription;6.54408457547305e-08!GO:0009055;electron carrier activity;8.47470457170446e-08!GO:0008047;enzyme activator activity;9.76830459245561e-08!GO:0005774;vacuolar membrane;1.02279914832918e-07!GO:0006461;protein complex assembly;1.28145230636864e-07!GO:0051726;regulation of cell cycle;1.41384706401181e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;1.44585951524834e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;1.44585951524834e-07!GO:0046034;ATP metabolic process;1.45860750003263e-07!GO:0000074;regulation of progression through cell cycle;1.51935345936856e-07!GO:0016469;proton-transporting two-sector ATPase complex;1.58422250445267e-07!GO:0009260;ribonucleotide biosynthetic process;1.68524537876402e-07!GO:0044453;nuclear membrane part;1.72955626703523e-07!GO:0009142;nucleoside triphosphate biosynthetic process;1.81547457528697e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.81547457528697e-07!GO:0044440;endosomal part;1.94309540402735e-07!GO:0010008;endosome membrane;1.94309540402735e-07!GO:0048468;cell development;1.94360258702214e-07!GO:0015078;hydrogen ion transmembrane transporter activity;2.08884206374389e-07!GO:0016881;acid-amino acid ligase activity;2.1559920678478e-07!GO:0044432;endoplasmic reticulum part;2.40829925744739e-07!GO:0003713;transcription coactivator activity;2.43665910678962e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.44535665127181e-07!GO:0009144;purine nucleoside triphosphate metabolic process;2.44535665127181e-07!GO:0007264;small GTPase mediated signal transduction;2.45427801545669e-07!GO:0009199;ribonucleoside triphosphate metabolic process;2.92929891665861e-07!GO:0008565;protein transporter activity;3.0744932491715e-07!GO:0016879;ligase activity, forming carbon-nitrogen bonds;3.26983613720616e-07!GO:0042775;organelle ATP synthesis coupled electron transport;3.81082098137592e-07!GO:0042773;ATP synthesis coupled electron transport;3.81082098137592e-07!GO:0030964;NADH dehydrogenase complex (quinone);4.1931208980426e-07!GO:0045271;respiratory chain complex I;4.1931208980426e-07!GO:0005747;mitochondrial respiratory chain complex I;4.1931208980426e-07!GO:0045786;negative regulation of progression through cell cycle;4.26337149759937e-07!GO:0044437;vacuolar part;4.57304642980676e-07!GO:0005793;ER-Golgi intermediate compartment;5.10197222148385e-07!GO:0009889;regulation of biosynthetic process;5.1059784074334e-07!GO:0006917;induction of apoptosis;5.36975366196213e-07!GO:0009141;nucleoside triphosphate metabolic process;7.38226265753013e-07!GO:0005765;lysosomal membrane;7.63613111159977e-07!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;7.95682049070163e-07!GO:0031326;regulation of cellular biosynthetic process;8.0714364688467e-07!GO:0012502;induction of programmed cell death;8.70206673116202e-07!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;8.80502686888602e-07!GO:0043228;non-membrane-bound organelle;8.80502686888602e-07!GO:0043232;intracellular non-membrane-bound organelle;8.80502686888602e-07!GO:0051188;cofactor biosynthetic process;9.00687811721069e-07!GO:0031982;vesicle;1.108226067382e-06!GO:0032561;guanyl ribonucleotide binding;1.24160643916186e-06!GO:0019001;guanyl nucleotide binding;1.24160643916186e-06!GO:0004386;helicase activity;1.41776860444629e-06!GO:0016044;membrane organization and biogenesis;1.42581239308553e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;1.58031895839441e-06!GO:0009108;coenzyme biosynthetic process;1.58093208233478e-06!GO:0005839;proteasome core complex (sensu Eukaryota);1.65919459989625e-06!GO:0006752;group transfer coenzyme metabolic process;1.92373701178365e-06!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;2.26306712530258e-06!GO:0015399;primary active transmembrane transporter activity;2.26306712530258e-06!GO:0016563;transcription activator activity;2.70615365576895e-06!GO:0008026;ATP-dependent helicase activity;3.08259287008799e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;4.33890791597483e-06!GO:0019222;regulation of metabolic process;4.58390772167262e-06!GO:0016568;chromatin modification;5.02790203588437e-06!GO:0042175;nuclear envelope-endoplasmic reticulum network;5.32761065892243e-06!GO:0031252;leading edge;6.49051562142636e-06!GO:0005789;endoplasmic reticulum membrane;6.58144995340557e-06!GO:0006954;inflammatory response;7.93344825571393e-06!GO:0031410;cytoplasmic vesicle;8.3894974620868e-06!GO:0006357;regulation of transcription from RNA polymerase II promoter;9.33541979338792e-06!GO:0050657;nucleic acid transport;9.48864657607696e-06!GO:0051236;establishment of RNA localization;9.48864657607696e-06!GO:0050658;RNA transport;9.48864657607696e-06!GO:0004298;threonine endopeptidase activity;9.61923571736081e-06!GO:0030695;GTPase regulator activity;1.02989337863927e-05!GO:0006325;establishment and/or maintenance of chromatin architecture;1.04736121984931e-05!GO:0030099;myeloid cell differentiation;1.1315715742443e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;1.15452126364489e-05!GO:0016197;endosome transport;1.16994267955058e-05!GO:0003714;transcription corepressor activity;1.17821354551249e-05!GO:0005643;nuclear pore;1.2505746587857e-05!GO:0006403;RNA localization;1.42910764484003e-05!GO:0031980;mitochondrial lumen;1.61797538061598e-05!GO:0005759;mitochondrial matrix;1.61797538061598e-05!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.83319637088179e-05!GO:0005096;GTPase activator activity;1.96837370902906e-05!GO:0031988;membrane-bound vesicle;2.05468473760542e-05!GO:0006323;DNA packaging;2.35331901058e-05!GO:0032446;protein modification by small protein conjugation;2.45594411200155e-05!GO:0051338;regulation of transferase activity;2.77921742830063e-05!GO:0022402;cell cycle process;3.07668429223116e-05!GO:0031902;late endosome membrane;3.26912938025964e-05!GO:0045321;leukocyte activation;3.3032995493171e-05!GO:0043492;ATPase activity, coupled to movement of substances;3.33145744426596e-05!GO:0016567;protein ubiquitination;3.34184365247962e-05!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;3.52604539052853e-05!GO:0006888;ER to Golgi vesicle-mediated transport;3.71543986208923e-05!GO:0030097;hemopoiesis;4.02556751192302e-05!GO:0003724;RNA helicase activity;4.67385795852694e-05!GO:0051789;response to protein stimulus;4.8041020170947e-05!GO:0006986;response to unfolded protein;4.8041020170947e-05!GO:0043566;structure-specific DNA binding;5.11698279314162e-05!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;5.20420647281115e-05!GO:0043549;regulation of kinase activity;5.59053497191119e-05!GO:0005769;early endosome;6.47112268874484e-05!GO:0048475;coated membrane;6.75810847994184e-05!GO:0030117;membrane coat;6.75810847994184e-05!GO:0030120;vesicle coat;7.06462610166978e-05!GO:0030662;coated vesicle membrane;7.06462610166978e-05!GO:0051336;regulation of hydrolase activity;7.15576017542984e-05!GO:0016023;cytoplasmic membrane-bound vesicle;7.18037288214598e-05!GO:0006401;RNA catabolic process;7.31866493724141e-05!GO:0006897;endocytosis;7.58788009127134e-05!GO:0010324;membrane invagination;7.58788009127134e-05!GO:0045259;proton-transporting ATP synthase complex;7.69933602788304e-05!GO:0045859;regulation of protein kinase activity;7.69933602788304e-05!GO:0046930;pore complex;7.96522718387656e-05!GO:0005083;small GTPase regulator activity;8.03280024185764e-05!GO:0008632;apoptotic program;9.46785530384898e-05!GO:0003697;single-stranded DNA binding;0.000106255446089871!GO:0051707;response to other organism;0.000106465368171598!GO:0051028;mRNA transport;0.000108331563079733!GO:0045892;negative regulation of transcription, DNA-dependent;0.000112587267525258!GO:0006974;response to DNA damage stimulus;0.000113833962172104!GO:0008234;cysteine-type peptidase activity;0.000113833962172104!GO:0006613;cotranslational protein targeting to membrane;0.000121571427121203!GO:0006952;defense response;0.000121696280500578!GO:0046822;regulation of nucleocytoplasmic transport;0.000122751851311517!GO:0009893;positive regulation of metabolic process;0.000123697941200698!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;0.000128655829270385!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;0.000134086588496787!GO:0009060;aerobic respiration;0.000170496951724551!GO:0004674;protein serine/threonine kinase activity;0.000173509856419413!GO:0030532;small nuclear ribonucleoprotein complex;0.000196923088936831!GO:0046983;protein dimerization activity;0.000200832546898852!GO:0006818;hydrogen transport;0.000212769131797946!GO:0000245;spliceosome assembly;0.00022107230633788!GO:0001816;cytokine production;0.000249076192028411!GO:0005057;receptor signaling protein activity;0.000250047649171223!GO:0044431;Golgi apparatus part;0.000283523857293162!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000290319418095987!GO:0005885;Arp2/3 protein complex;0.000303159703344979!GO:0051168;nuclear export;0.000316861517122782!GO:0015992;proton transport;0.000322137416770397!GO:0007050;cell cycle arrest;0.000347879800543494!GO:0030036;actin cytoskeleton organization and biogenesis;0.00035316020709345!GO:0031323;regulation of cellular metabolic process;0.000356774036468305!GO:0007265;Ras protein signal transduction;0.000362633683574719!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000387963596721681!GO:0022890;inorganic cation transmembrane transporter activity;0.000392237334738601!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000404561112431609!GO:0065002;intracellular protein transport across a membrane;0.000424204165595085!GO:0007034;vacuolar transport;0.00042806827580317!GO:0002757;immune response-activating signal transduction;0.00042806827580317!GO:0008186;RNA-dependent ATPase activity;0.000432318559443261!GO:0005798;Golgi-associated vesicle;0.0004335219756865!GO:0006402;mRNA catabolic process;0.000446532072630042!GO:0032940;secretion by cell;0.000449299710448823!GO:0051276;chromosome organization and biogenesis;0.000495733271554525!GO:0005741;mitochondrial outer membrane;0.000502487631163474!GO:0007033;vacuole organization and biogenesis;0.000553150051943063!GO:0042254;ribosome biogenesis and assembly;0.000555455300429932!GO:0007041;lysosomal transport;0.000564848105485214!GO:0007040;lysosome organization and biogenesis;0.000571611241728229!GO:0002520;immune system development;0.000579536899530831!GO:0045333;cellular respiration;0.000579536899530831!GO:0033157;regulation of intracellular protein transport;0.00058039098696743!GO:0042306;regulation of protein import into nucleus;0.00058039098696743!GO:0005637;nuclear inner membrane;0.000609566548083048!GO:0043085;positive regulation of catalytic activity;0.000629394621465164!GO:0051223;regulation of protein transport;0.000633407239420807!GO:0031202;RNA splicing factor activity, transesterification mechanism;0.000642118263556512!GO:0018193;peptidyl-amino acid modification;0.000653718697625041!GO:0046649;lymphocyte activation;0.00066612541952238!GO:0003729;mRNA binding;0.000692622671466531!GO:0002252;immune effector process;0.000692622671466531!GO:0005761;mitochondrial ribosome;0.000737449107795309!GO:0000313;organellar ribosome;0.000737449107795309!GO:0002764;immune response-regulating signal transduction;0.000765601551260832!GO:0006281;DNA repair;0.000775064459743012!GO:0045941;positive regulation of transcription;0.000809243127028778!GO:0016281;eukaryotic translation initiation factor 4F complex;0.000823074486300801!GO:0046519;sphingoid metabolic process;0.000836558515756476!GO:0009117;nucleotide metabolic process;0.000841522292854431!GO:0016740;transferase activity;0.000841522292854431!GO:0001726;ruffle;0.000893928475238588!GO:0002521;leukocyte differentiation;0.000896333518479989!GO:0009611;response to wounding;0.00093305481181246!GO:0019221;cytokine and chemokine mediated signaling pathway;0.000935003778570304!GO:0060090;molecular adaptor activity;0.000951119807953609!GO:0048534;hemopoietic or lymphoid organ development;0.00101733583891022!GO:0007005;mitochondrion organization and biogenesis;0.00103600844500796!GO:0001775;cell activation;0.00103976125887171!GO:0002274;myeloid leukocyte activation;0.00105351834338169!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.00107070058014593!GO:0051427;hormone receptor binding;0.00111895935962338!GO:0004004;ATP-dependent RNA helicase activity;0.00117410133609284!GO:0000151;ubiquitin ligase complex;0.00118445713649181!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00121966643856576!GO:0045893;positive regulation of transcription, DNA-dependent;0.00124966448958259!GO:0045637;regulation of myeloid cell differentiation;0.00129013263136977!GO:0044262;cellular carbohydrate metabolic process;0.00140875593617742!GO:0031325;positive regulation of cellular metabolic process;0.00148113042202883!GO:0007259;JAK-STAT cascade;0.00148576242871545!GO:0031968;organelle outer membrane;0.00148597183704462!GO:0006672;ceramide metabolic process;0.00149388270607275!GO:0006612;protein targeting to membrane;0.00157986585099108!GO:0033116;ER-Golgi intermediate compartment membrane;0.00165712610471048!GO:0042990;regulation of transcription factor import into nucleus;0.00165712610471048!GO:0042991;transcription factor import into nucleus;0.00165712610471048!GO:0030149;sphingolipid catabolic process;0.00166472452488828!GO:0019867;outer membrane;0.00169542613146108!GO:0005667;transcription factor complex;0.0017191368618101!GO:0051090;regulation of transcription factor activity;0.00172735297296293!GO:0035257;nuclear hormone receptor binding;0.00177066548470113!GO:0005099;Ras GTPase activator activity;0.0018003282043441!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.0018580996584814!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.00188548231167566!GO:0042802;identical protein binding;0.00194261584581136!GO:0022415;viral reproductive process;0.00198946565585404!GO:0045454;cell redox homeostasis;0.00202959576600897!GO:0016301;kinase activity;0.00219217059434436!GO:0002429;immune response-activating cell surface receptor signaling pathway;0.00222088530072167!GO:0065004;protein-DNA complex assembly;0.00225161455532349!GO:0031072;heat shock protein binding;0.00231393023803062!GO:0042110;T cell activation;0.00233544346496013!GO:0006091;generation of precursor metabolites and energy;0.00266069311314261!GO:0008654;phospholipid biosynthetic process;0.00280835679435043!GO:0030029;actin filament-based process;0.00295642800531927!GO:0006919;caspase activation;0.00301700936986791!GO:0006099;tricarboxylic acid cycle;0.003028243914053!GO:0046356;acetyl-CoA catabolic process;0.003028243914053!GO:0043623;cellular protein complex assembly;0.00313933499516559!GO:0010468;regulation of gene expression;0.0031976066503288!GO:0004197;cysteine-type endopeptidase activity;0.00329933265450283!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00338686748253038!GO:0043281;regulation of caspase activity;0.00359582287630755!GO:0002250;adaptive immune response;0.0036662803861025!GO:0002460;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0036662803861025!GO:0043087;regulation of GTPase activity;0.00376575525649978!GO:0002768;immune response-regulating cell surface receptor signaling pathway;0.00380695542792243!GO:0045792;negative regulation of cell size;0.00397403822776262!GO:0043280;positive regulation of caspase activity;0.00402839923477994!GO:0051187;cofactor catabolic process;0.00402839923477994!GO:0019904;protein domain specific binding;0.00410410395461406!GO:0016251;general RNA polymerase II transcription factor activity;0.00427490750697332!GO:0033673;negative regulation of kinase activity;0.00427490750697332!GO:0006469;negative regulation of protein kinase activity;0.00427490750697332!GO:0009719;response to endogenous stimulus;0.00431859615082447!GO:0043433;negative regulation of transcription factor activity;0.00471066928912697!GO:0016779;nucleotidyltransferase activity;0.00480752208549614!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00481224940796987!GO:0032386;regulation of intracellular transport;0.00484395186196079!GO:0000139;Golgi membrane;0.00486522104578122!GO:0030308;negative regulation of cell growth;0.00489673132744896!GO:0051348;negative regulation of transferase activity;0.00516159425442566!GO:0002443;leukocyte mediated immunity;0.00520737659785975!GO:0008383;manganese superoxide dismutase activity;0.00521983672436161!GO:0001315;age-dependent response to reactive oxygen species;0.00521983672436161!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00529206723883078!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00529206723883078!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00529206723883078!GO:0048487;beta-tubulin binding;0.00531482151077402!GO:0030041;actin filament polymerization;0.00542217676783195!GO:0003702;RNA polymerase II transcription factor activity;0.00550136552986057!GO:0006468;protein amino acid phosphorylation;0.00553107779109251!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.00569006971562992!GO:0009165;nucleotide biosynthetic process;0.00570329509427348!GO:0006891;intra-Golgi vesicle-mediated transport;0.00586708450803264!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;0.00615697498032081!GO:0004812;aminoacyl-tRNA ligase activity;0.00615697498032081!GO:0016875;ligase activity, forming carbon-oxygen bonds;0.00615697498032081!GO:0019377;glycolipid catabolic process;0.00628479357784457!GO:0001817;regulation of cytokine production;0.00633515956277607!GO:0030218;erythrocyte differentiation;0.00636482941870835!GO:0006607;NLS-bearing substrate import into nucleus;0.00665477631161498!GO:0019882;antigen processing and presentation;0.00674969910446717!GO:0051098;regulation of binding;0.00694923729442658!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.00697519624712748!GO:0002682;regulation of immune system process;0.00718667650988515!GO:0005070;SH3/SH2 adaptor activity;0.00719454685283826!GO:0006084;acetyl-CoA metabolic process;0.0072554602248916!GO:0006643;membrane lipid metabolic process;0.00734302618040915!GO:0004185;serine carboxypeptidase activity;0.0075409353009155!GO:0043021;ribonucleoprotein binding;0.0076448583877002!GO:0031901;early endosome membrane;0.00771629343576635!GO:0002684;positive regulation of immune system process;0.00786927559381719!GO:0002440;production of molecular mediator of immune response;0.00786927559381719!GO:0003690;double-stranded DNA binding;0.00788251882285851!GO:0051059;NF-kappaB binding;0.00803046629415081!GO:0016363;nuclear matrix;0.00824747624782448!GO:0006352;transcription initiation;0.00825882271024749!GO:0043038;amino acid activation;0.00825882271024749!GO:0006418;tRNA aminoacylation for protein translation;0.00825882271024749!GO:0043039;tRNA aminoacylation;0.00825882271024749!GO:0045045;secretory pathway;0.00857530270297884!GO:0009109;coenzyme catabolic process;0.00883106272919603!GO:0050851;antigen receptor-mediated signaling pathway;0.00898818266939043!GO:0005484;SNAP receptor activity;0.00927298920848637!GO:0031625;ubiquitin protein ligase binding;0.00944878688299155!GO:0006399;tRNA metabolic process;0.00950647419362655!GO:0019220;regulation of phosphate metabolic process;0.00961687338475789!GO:0051174;regulation of phosphorus metabolic process;0.00961687338475789!GO:0016072;rRNA metabolic process;0.0096939803123348!GO:0006350;transcription;0.0100424836749021!GO:0001819;positive regulation of cytokine production;0.0100879160311864!GO:0030867;rough endoplasmic reticulum membrane;0.0101579326749886!GO:0042613;MHC class II protein complex;0.0102685534967711!GO:0030027;lamellipodium;0.0102685534967711!GO:0003725;double-stranded RNA binding;0.0104386790788008!GO:0050778;positive regulation of immune response;0.0108795033984538!GO:0005048;signal sequence binding;0.0108795033984538!GO:0006749;glutathione metabolic process;0.0112933195696058!GO:0006364;rRNA processing;0.0114045565335299!GO:0000082;G1/S transition of mitotic cell cycle;0.0116315310692629!GO:0002822;regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.;0.0119729657784862!GO:0002819;regulation of adaptive immune response;0.0119729657784862!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0123252349415274!GO:0002237;response to molecule of bacterial origin;0.0128425481495472!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.0129035070909728!GO:0005813;centrosome;0.013019622702336!GO:0046479;glycosphingolipid catabolic process;0.0132370869385488!GO:0030658;transport vesicle membrane;0.0134913237178807!GO:0006333;chromatin assembly or disassembly;0.0138957627664174!GO:0048500;signal recognition particle;0.0140946395157397!GO:0030127;COPII vesicle coat;0.0143364226563579!GO:0012507;ER to Golgi transport vesicle membrane;0.0143364226563579!GO:0030134;ER to Golgi transport vesicle;0.0145996287578542!GO:0003727;single-stranded RNA binding;0.014605030835816!GO:0051345;positive regulation of hydrolase activity;0.0146849739013335!GO:0045639;positive regulation of myeloid cell differentiation;0.0147606173867997!GO:0032763;regulation of mast cell cytokine production;0.0156892783443404!GO:0032762;mast cell cytokine production;0.0156892783443404!GO:0008361;regulation of cell size;0.015918555558701!GO:0019210;kinase inhibitor activity;0.016170113954939!GO:0002467;germinal center formation;0.0161809931535366!GO:0004860;protein kinase inhibitor activity;0.0162533970096673!GO:0050776;regulation of immune response;0.0162787821657697!GO:0046466;membrane lipid catabolic process;0.0162935410961221!GO:0002444;myeloid leukocyte mediated immunity;0.0165127357469763!GO:0006611;protein export from nucleus;0.0167548373092034!GO:0030503;regulation of cell redox homeostasis;0.0169486591938124!GO:0000287;magnesium ion binding;0.0174838755523055!GO:0030693;caspase activity;0.0175938478498476!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0178440320930271!GO:0004177;aminopeptidase activity;0.0178801340127988!GO:0019883;antigen processing and presentation of endogenous antigen;0.0179708788398849!GO:0043621;protein self-association;0.0183550122784612!GO:0006458;'de novo' protein folding;0.0183672846619136!GO:0051084;'de novo' posttranslational protein folding;0.0183672846619136!GO:0008139;nuclear localization sequence binding;0.0187198768170983!GO:0043071;positive regulation of non-apoptotic programmed cell death;0.0187561624269169!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0187615944964741!GO:0015631;tubulin binding;0.0191757714028937!GO:0017166;vinculin binding;0.0194278732617532!GO:0030224;monocyte differentiation;0.0197763771586867!GO:0002253;activation of immune response;0.0197763771586867!GO:0043300;regulation of leukocyte degranulation;0.0202658991137045!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0205937120225816!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0206003061643501!GO:0045047;protein targeting to ER;0.0206003061643501!GO:0045926;negative regulation of growth;0.0207122759335113!GO:0000209;protein polyubiquitination;0.0208576052416494!GO:0045646;regulation of erythrocyte differentiation;0.0208594481478862!GO:0019079;viral genome replication;0.0208594481478862!GO:0008637;apoptotic mitochondrial changes;0.0215734570240314!GO:0002573;myeloid leukocyte differentiation;0.0217058294615755!GO:0048471;perinuclear region of cytoplasm;0.0218605347104634!GO:0015923;mannosidase activity;0.022884144836431!GO:0002697;regulation of immune effector process;0.0232382558870923!GO:0019843;rRNA binding;0.0232382558870923!GO:0030518;steroid hormone receptor signaling pathway;0.0233464001446826!GO:0000165;MAPKKK cascade;0.0233946991461349!GO:0017091;AU-rich element binding;0.0234500772962311!GO:0050779;RNA destabilization;0.0234500772962311!GO:0000289;poly(A) tail shortening;0.0234500772962311!GO:0051049;regulation of transport;0.0236215128030354!GO:0008286;insulin receptor signaling pathway;0.0238441817421525!GO:0033367;protein localization in mast cell secretory granule;0.0242558749435681!GO:0033365;protein localization in organelle;0.0242558749435681!GO:0033371;T cell secretory granule organization and biogenesis;0.0242558749435681!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.0242558749435681!GO:0033375;protease localization in T cell secretory granule;0.0242558749435681!GO:0042629;mast cell granule;0.0242558749435681!GO:0033377;maintenance of protein localization in T cell secretory granule;0.0242558749435681!GO:0033364;mast cell secretory granule organization and biogenesis;0.0242558749435681!GO:0033380;granzyme B localization in T cell secretory granule;0.0242558749435681!GO:0033379;maintenance of protease localization in T cell secretory granule;0.0242558749435681!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.0242558749435681!GO:0033368;protease localization in mast cell secretory granule;0.0242558749435681!GO:0033366;protein localization in secretory granule;0.0242558749435681!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.0242558749435681!GO:0033374;protein localization in T cell secretory granule;0.0242558749435681!GO:0043022;ribosome binding;0.0243595876686073!GO:0002224;toll-like receptor signaling pathway;0.0247250332421601!GO:0002221;pattern recognition receptor signaling pathway;0.0247250332421601!GO:0000118;histone deacetylase complex;0.024734587708129!GO:0042113;B cell activation;0.0248695557782761!GO:0006665;sphingolipid metabolic process;0.0248695557782761!GO:0032318;regulation of Ras GTPase activity;0.0248695557782761!GO:0030521;androgen receptor signaling pathway;0.024963778553811!GO:0046979;TAP2 binding;0.0250269191841753!GO:0046977;TAP binding;0.0250269191841753!GO:0046978;TAP1 binding;0.0250269191841753!GO:0000339;RNA cap binding;0.0251486044333197!GO:0048146;positive regulation of fibroblast proliferation;0.0257293673152301!GO:0051092;activation of NF-kappaB transcription factor;0.0258933431722732!GO:0045576;mast cell activation;0.0259917683239982!GO:0030258;lipid modification;0.0260502515962084!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0264220642872742!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0264220642872742!GO:0008333;endosome to lysosome transport;0.026706232150149!GO:0019901;protein kinase binding;0.0270240531095686!GO:0000049;tRNA binding;0.0272845091524987!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0274183416480218!GO:0030660;Golgi-associated vesicle membrane;0.0277329756242758!GO:0048144;fibroblast proliferation;0.0278082914414166!GO:0048145;regulation of fibroblast proliferation;0.0278082914414166!GO:0030133;transport vesicle;0.027933601815162!GO:0008629;induction of apoptosis by intracellular signals;0.0279469604673439!GO:0002449;lymphocyte mediated immunity;0.0286667628975753!GO:0005788;endoplasmic reticulum lumen;0.0286667628975753!GO:0019318;hexose metabolic process;0.028871109746114!GO:0005905;coated pit;0.0292217884755995!GO:0046966;thyroid hormone receptor binding;0.0293809341324654!GO:0015036;disulfide oxidoreductase activity;0.029718164710193!GO:0005815;microtubule organizing center;0.0300475965383534!GO:0042611;MHC protein complex;0.0302133870361867!GO:0019783;small conjugating protein-specific protease activity;0.030718726093741!GO:0051101;regulation of DNA binding;0.030745324559013!GO:0051252;regulation of RNA metabolic process;0.0310871433534619!GO:0043488;regulation of mRNA stability;0.0310871433534619!GO:0043487;regulation of RNA stability;0.0310871433534619!GO:0000785;chromatin;0.0310871433534619!GO:0007162;negative regulation of cell adhesion;0.0314107352931605!GO:0042348;NF-kappaB import into nucleus;0.0314107352931605!GO:0042345;regulation of NF-kappaB import into nucleus;0.0314107352931605!GO:0005996;monosaccharide metabolic process;0.031867502738233!GO:0051347;positive regulation of transferase activity;0.0318834325784291!GO:0050811;GABA receptor binding;0.0319569747284717!GO:0051247;positive regulation of protein metabolic process;0.0319865439101723!GO:0030176;integral to endoplasmic reticulum membrane;0.0321711170820749!GO:0043299;leukocyte degranulation;0.0326174378844835!GO:0043407;negative regulation of MAP kinase activity;0.0326842399478268!GO:0042221;response to chemical stimulus;0.0327329263636932!GO:0048002;antigen processing and presentation of peptide antigen;0.0328634030170028!GO:0006414;translational elongation;0.0335674988961843!GO:0030663;COPI coated vesicle membrane;0.0344564463105703!GO:0030126;COPI vesicle coat;0.0344564463105703!GO:0002718;regulation of cytokine production during immune response;0.034462156794893!GO:0002367;cytokine production during immune response;0.034462156794893!GO:0002700;regulation of production of molecular mediator of immune response;0.034462156794893!GO:0006465;signal peptide processing;0.0345759466484088!GO:0016049;cell growth;0.0345888482202434!GO:0005684;U2-dependent spliceosome;0.0355646372475914!GO:0051329;interphase of mitotic cell cycle;0.035956554504298!GO:0004843;ubiquitin-specific protease activity;0.0361533117134129!GO:0030137;COPI-coated vesicle;0.0365273293834402!GO:0016605;PML body;0.0365915534928814!GO:0006984;ER-nuclear signaling pathway;0.0365915534928814!GO:0046426;negative regulation of JAK-STAT cascade;0.0365915534928814!GO:0005791;rough endoplasmic reticulum;0.0368417063932821!GO:0042325;regulation of phosphorylation;0.0369557310423305!GO:0006509;membrane protein ectodomain proteolysis;0.0369557310423305!GO:0033619;membrane protein proteolysis;0.0369557310423305!GO:0004563;beta-N-acetylhexosaminidase activity;0.0374267165736413!GO:0032760;positive regulation of tumor necrosis factor production;0.0374710286418053!GO:0006516;glycoprotein catabolic process;0.0374850880529948!GO:0016791;phosphoric monoester hydrolase activity;0.0378554020738452!GO:0006595;polyamine metabolic process;0.0378722164330279!GO:0051540;metal cluster binding;0.0378722164330279!GO:0051536;iron-sulfur cluster binding;0.0378722164330279!GO:0008312;7S RNA binding;0.0378881633894469!GO:0045113;regulation of integrin biosynthetic process;0.0381338032889604!GO:0045112;integrin biosynthetic process;0.0381338032889604!GO:0008287;protein serine/threonine phosphatase complex;0.0381338032889604!GO:0002824;positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0381338032889604!GO:0002821;positive regulation of adaptive immune response;0.0381338032889604!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0389710908564843!GO:0051881;regulation of mitochondrial membrane potential;0.0391387701838997!GO:0006689;ganglioside catabolic process;0.0394388896114981!GO:0030031;cell projection biogenesis;0.0394388896114981!GO:0005669;transcription factor TFIID complex;0.0397984322635806!GO:0048872;homeostasis of number of cells;0.040119248841567!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0407946881074473!GO:0051056;regulation of small GTPase mediated signal transduction;0.0408136753227993!GO:0045936;negative regulation of phosphate metabolic process;0.0410300373662713!GO:0016491;oxidoreductase activity;0.0410416706362075!GO:0030118;clathrin coat;0.0410946962343432!GO:0000096;sulfur amino acid metabolic process;0.0411172996930393!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0411382172047917!GO:0019058;viral infectious cycle;0.0413494522010679!GO:0046467;membrane lipid biosynthetic process;0.0421799013672738!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0432520537097872!GO:0005100;Rho GTPase activator activity;0.0435039239557995!GO:0007006;mitochondrial membrane organization and biogenesis;0.0446792141944213!GO:0051251;positive regulation of lymphocyte activation;0.0456075079447523!GO:0000278;mitotic cell cycle;0.045788580576924!GO:0033549;MAP kinase phosphatase activity;0.045860729197243!GO:0017017;MAP kinase tyrosine/serine/threonine phosphatase activity;0.045860729197243!GO:0051085;chaperone cofactor-dependent protein folding;0.0474533991544149!GO:0046578;regulation of Ras protein signal transduction;0.0477873703063861!GO:0008017;microtubule binding;0.0477989889580216!GO:0000738;DNA catabolic process, exonucleolytic;0.0489079438517318!GO:0033033;negative regulation of myeloid cell apoptosis;0.0489079438517318!GO:0001803;regulation of type III hypersensitivity;0.0489079438517318!GO:0032733;positive regulation of interleukin-10 production;0.0489079438517318!GO:0033025;regulation of mast cell apoptosis;0.0489079438517318!GO:0001805;positive regulation of type III hypersensitivity;0.0489079438517318!GO:0033023;mast cell homeostasis;0.0489079438517318!GO:0002431;Fc receptor mediated stimulatory signaling pathway;0.0489079438517318!GO:0033032;regulation of myeloid cell apoptosis;0.0489079438517318!GO:0001802;type III hypersensitivity;0.0489079438517318!GO:0033028;myeloid cell apoptosis;0.0489079438517318!GO:0042590;antigen processing and presentation of exogenous peptide antigen via MHC class I;0.0489079438517318!GO:0033026;negative regulation of mast cell apoptosis;0.0489079438517318!GO:0033024;mast cell apoptosis;0.0489079438517318!GO:0030217;T cell differentiation;0.0490719221086575!GO:0035035;histone acetyltransferase binding;0.0491851430593511!GO:0005152;interleukin-1 receptor antagonist activity;0.0497037653825596!GO:0030353;fibroblast growth factor receptor antagonist activity;0.0497037653825596!GO:0008624;induction of apoptosis by extracellular signals;0.0498664934523597 | |||
|sample_id=11872 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue= | |||
|top_motifs=STAT5{A,B}:5.12668448578;STAT2,4,6:5.03089260174;FOSL2:4.35330268841;NFE2:4.13587006393;NFE2L2:3.97044467941;IRF7:3.88216735301;BACH2:3.79385448957;FOS_FOS{B,L1}_JUN{B,D}:3.68954908866;CEBPA,B_DDIT3:3.65082218866;STAT1,3:3.63491530742;IRF1,2:3.48788532449;PAX2:3.29444876047;SREBF1,2:3.23344360894;FOXP3:2.8994923943;SPIB:2.83128537095;HLF:2.82119223775;EP300:2.68986224218;SPI1:2.58160095642;NFE2L1:2.52860649275;ATF4:2.45463286651;ATF5_CREB3:2.45165759864;ETS1,2:2.36346500426;DMAP1_NCOR{1,2}_SMARC:2.33660139343;ZBTB16:2.26837197234;ATF6:2.22837056231;NR1H4:2.12577640531;NANOG{mouse}:2.08186889786;NFIL3:2.06869016154;FOXN1:2.06861133661;NFKB1_REL_RELA:1.79006153193;CREB1:1.76535031658;RUNX1..3:1.74508394576;HSF1,2:1.47855772079;TGIF1:1.40856811394;MAFB:1.29031364784;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.2606442459;BPTF:1.24505782279;JUN:1.21831284565;ELF1,2,4:1.15230445072;FOXD3:1.13912146131;ALX4:1.12218186949;PDX1:1.12031323798;PITX1..3:1.11107397678;CDX1,2,4:1.07765365543;PAX8:1.07160746652;ATF2:0.9910452418;PAX3,7:0.847075602315;HIF1A:0.835466443252;NFATC1..3:0.821466804411;PAX4:0.797434560957;HMGA1,2:0.777929458913;TLX2:0.677333480341;FOXP1:0.651101752959;ESRRA:0.579693231845;HBP1_HMGB_SSRP1_UBTF:0.57091417527;IKZF2:0.506790634257;NKX6-1,2:0.458215435238;SRF:0.421289881899;HMX1:0.419651337906;NR6A1:0.398340617483;GLI1..3:0.351891202323;XBP1:0.280600748722;GATA4:0.261480362833;SMAD1..7,9:0.243715164772;RFX2..5_RFXANK_RFXAP:0.188497340558;AHR_ARNT_ARNT2:0.159298558501;HOX{A6,A7,B6,B7}:0.112234129361;HES1:0.105491649113;PRDM1:0.0822452255267;PPARG:0.0633856732171;FOXM1:0.0500906322778;ESR1:0.0331181296572;NANOG:0.00153848505765;FOXO1,3,4:-0.0134042499449;HOX{A5,B5}:-0.0898213355183;OCT4_SOX2{dimer}:-0.163367040004;FOX{D1,D2}:-0.173285623469;RXRA_VDR{dimer}:-0.183523824702;TBP:-0.184560764647;TFCP2:-0.189284414088;FOXL1:-0.203166070783;NKX3-1:-0.248654715694;EN1,2:-0.253523965796;MYB:-0.257064720997;NKX3-2:-0.276373976464;RREB1:-0.296802932587;EGR1..3:-0.306828697872;ALX1:-0.340712723433;MEF2{A,B,C,D}:-0.425192470982;RBPJ:-0.449585812445;POU1F1:-0.487722152729;POU2F1..3:-0.557511552512;HOXA9_MEIS1:-0.566312264761;RXR{A,B,G}:-0.691360253237;POU5F1:-0.698324874337;MZF1:-0.703405132348;FOX{F1,F2,J1}:-0.712361755655;TFAP4:-0.732205739743;SPZ1:-0.76546576034;TOPORS:-0.799738241691;PAX1,9:-0.833390718504;T:-0.84904816571;REST:-0.857118518586;AIRE:-0.868855166708;HNF4A_NR2F1,2:-0.871183699088;IKZF1:-0.873003064988;DBP:-0.897578840758;VSX1,2:-0.906223033922;ZNF384:-0.945011471813;MYFfamily:-1.00273752237;POU6F1:-1.01709568311;GZF1:-1.02786299085;SOX2:-1.04924576787;NHLH1,2:-1.09736491452;MED-1{core}:-1.10108705858;NKX2-2,8:-1.12302078828;PAX6:-1.13852625057;HNF1A:-1.15137503476;PRRX1,2:-1.17059312582;ZNF238:-1.17962305522;CUX2:-1.19127184369;RXR{A,B,G}_{NR1H2,PPAR}dimers:-1.2286112904;GATA6:-1.24913383098;TEF:-1.25211526109;MYBL2:-1.31867271189;RORA:-1.336407544;MTE{core}:-1.34399193791;TFAP2B:-1.38433734524;NKX2-3_NKX2-5:-1.40420945834;ZBTB6:-1.41058005389;ZFP161:-1.46063890475;PATZ1:-1.48942899278;UFEwm:-1.50612572237;NKX2-1,4:-1.51180519922;TAL1_TCF{3,4,12}:-1.5213021723;EVI1:-1.528880108;MTF1:-1.53159483942;ZEB1:-1.56479077072;BREu{core}:-1.57289241142;GCM1,2:-1.57705868003;TEAD1:-1.57805002556;RFX1:-1.59136458035;MYOD1:-1.61796159247;XCPE1{core}:-1.64007440977;SP1:-1.64273274375;TFAP2{A,C}:-1.6614132917;ADNP_IRX_SIX_ZHX:-1.70956599049;GTF2A1,2:-1.71468151743;NR3C1:-1.71480015695;SOX5:-1.73416802447;MAZ:-1.74766102475;FOXA2:-1.75510185931;TP53:-1.77576688739;E2F1..5:-1.78407463462;SOX{8,9,10}:-1.7904142238;TLX1..3_NFIC{dimer}:-1.83192928968;KLF4:-1.8381477702;GTF2I:-1.8493496706;SNAI1..3:-1.91775042518;ZIC1..3:-1.97403977245;ZNF148:-1.98160710731;HOX{A4,D4}:-1.98738921054;TFDP1:-1.99803967906;ONECUT1,2:-2.04279279928;HAND1,2:-2.05974530821;bHLH_family:-2.08396051588;HIC1:-2.09975967271;GFI1B:-2.14037461048;CRX:-2.17578353558;LMO2:-2.20902119273;EBF1:-2.21032297014;NFY{A,B,C}:-2.28284406139;TBX4,5:-2.29700576208;ELK1,4_GABP{A,B1}:-2.31832110651;POU3F1..4:-2.33147520338;NFIX:-2.33606849779;FOX{I1,J2}:-2.3406598515;ZNF423:-2.4442591629;PBX1:-2.50949805721;CDC5L:-2.52386838421;SOX17:-2.56505132643;FOXQ1:-2.59948962023;NR5A1,2:-2.71595325871;NRF1:-2.87442802939;GFI1:-2.93728341334;YY1:-2.97542797272;AR:-3.06800352126;PAX5:-3.13341234337;ARID5B:-3.25121076633;LHX3,4:-3.39587309478;ZNF143:-3.5859174552;LEF1_TCF7_TCF7L1,2:-3.69292127005 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11872-125B9;search_select_hide=table117:FF:11872-125B9 | |||
}} | }} |
Latest revision as of 18:25, 4 June 2020
Name: | CD14+ monocytes - treated with Trehalose dimycolate (TDM), donor2 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13483 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13483
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13483
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0749 |
10 | 10 | 0.018 |
100 | 100 | 0.916 |
101 | 101 | 0.836 |
102 | 102 | 0.767 |
103 | 103 | 0.378 |
104 | 104 | 0.609 |
105 | 105 | 0.217 |
106 | 106 | 6.8682e-4 |
107 | 107 | 0.211 |
108 | 108 | 0.94 |
109 | 109 | 0.303 |
11 | 11 | 0.156 |
110 | 110 | 0.134 |
111 | 111 | 0.023 |
112 | 112 | 0.322 |
113 | 113 | 0.43 |
114 | 114 | 0.0118 |
115 | 115 | 0.306 |
116 | 116 | 0.844 |
117 | 117 | 0.0644 |
118 | 118 | 0.166 |
119 | 119 | 0.118 |
12 | 12 | 0.376 |
120 | 120 | 0.708 |
121 | 121 | 0.468 |
122 | 122 | 0.801 |
123 | 123 | 0.0351 |
124 | 124 | 0.749 |
125 | 125 | 0.369 |
126 | 126 | 0.343 |
127 | 127 | 0.436 |
128 | 128 | 0.032 |
129 | 129 | 0.537 |
13 | 13 | 0.106 |
130 | 130 | 0.0767 |
131 | 131 | 0.573 |
132 | 132 | 0.0685 |
133 | 133 | 0.648 |
134 | 134 | 0.612 |
135 | 135 | 0.81 |
136 | 136 | 0.602 |
137 | 137 | 0.0149 |
138 | 138 | 0.153 |
139 | 139 | 0.0309 |
14 | 14 | 0.433 |
140 | 140 | 0.168 |
141 | 141 | 0.288 |
142 | 142 | 0.0968 |
143 | 143 | 0.0477 |
144 | 144 | 0.682 |
145 | 145 | 0.285 |
146 | 146 | 0.577 |
147 | 147 | 0.503 |
148 | 148 | 0.00931 |
149 | 149 | 0.939 |
15 | 15 | 0.169 |
150 | 150 | 0.433 |
151 | 151 | 0.361 |
152 | 152 | 0.232 |
153 | 153 | 0.778 |
154 | 154 | 0.319 |
155 | 155 | 0.732 |
156 | 156 | 0.484 |
157 | 157 | 0.395 |
158 | 158 | 0.0118 |
159 | 159 | 0.667 |
16 | 16 | 0.353 |
160 | 160 | 0.301 |
161 | 161 | 0.403 |
162 | 162 | 0.299 |
163 | 163 | 0.121 |
164 | 164 | 0.0747 |
165 | 165 | 0.147 |
166 | 166 | 0.702 |
167 | 167 | 0.083 |
168 | 168 | 0.381 |
169 | 169 | 0.00817 |
17 | 17 | 0.211 |
18 | 18 | 0.177 |
19 | 19 | 0.383 |
2 | 2 | 0.642 |
20 | 20 | 0.247 |
21 | 21 | 0.421 |
22 | 22 | 0.333 |
23 | 23 | 0.0444 |
24 | 24 | 0.345 |
25 | 25 | 0.394 |
26 | 26 | 0.0566 |
27 | 27 | 0.676 |
28 | 28 | 0.516 |
29 | 29 | 0.233 |
3 | 3 | 0.0959 |
30 | 30 | 0.439 |
31 | 31 | 0.849 |
32 | 32 | 0.813 |
33 | 33 | 0.316 |
34 | 34 | 0.71 |
35 | 35 | 0.17 |
36 | 36 | 0.0742 |
37 | 37 | 0.0775 |
38 | 38 | 0.388 |
39 | 39 | 0.844 |
4 | 4 | 0.944 |
40 | 40 | 0.251 |
41 | 41 | 0.0257 |
42 | 42 | 0.372 |
43 | 43 | 0.0429 |
44 | 44 | 0.993 |
45 | 45 | 0.929 |
46 | 46 | 0.151 |
47 | 47 | 0.502 |
48 | 48 | 0.462 |
49 | 49 | 0.123 |
5 | 5 | 0.276 |
50 | 50 | 0.931 |
51 | 51 | 0.445 |
52 | 52 | 0.394 |
53 | 53 | 0.39 |
54 | 54 | 0.368 |
55 | 55 | 0.41 |
56 | 56 | 0.701 |
57 | 57 | 0.665 |
58 | 58 | 0.122 |
59 | 59 | 0.35 |
6 | 6 | 0.711 |
60 | 60 | 0.0488 |
61 | 61 | 0.621 |
62 | 62 | 0.0637 |
63 | 63 | 0.5 |
64 | 64 | 0.411 |
65 | 65 | 0.23 |
66 | 66 | 0.224 |
67 | 67 | 0.576 |
68 | 68 | 0.927 |
69 | 69 | 0.578 |
7 | 7 | 0.278 |
70 | 70 | 0.0251 |
71 | 71 | 0.0377 |
72 | 72 | 0.211 |
73 | 73 | 0.203 |
74 | 74 | 0.15 |
75 | 75 | 0.124 |
76 | 76 | 0.174 |
77 | 77 | 0.596 |
78 | 78 | 0.108 |
79 | 79 | 0.296 |
8 | 8 | 0.39 |
80 | 80 | 0.493 |
81 | 81 | 0.302 |
82 | 82 | 0.205 |
83 | 83 | 0.0759 |
84 | 84 | 0.364 |
85 | 85 | 0.0195 |
86 | 86 | 0.0568 |
87 | 87 | 0.728 |
88 | 88 | 0.659 |
89 | 89 | 0.368 |
9 | 9 | 0.514 |
90 | 90 | 0.0745 |
91 | 91 | 0.221 |
92 | 92 | 0.211 |
93 | 93 | 0.502 |
94 | 94 | 0.0557 |
95 | 95 | 0.513 |
96 | 96 | 0.46 |
97 | 97 | 0.771 |
98 | 98 | 0.104 |
99 | 99 | 0.0594 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13483
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0011444 CD14-positive monocytes - treated with Trehalose dimycolate (TDM) sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000766 (myeloid leukocyte)
0000219 (motile cell)
0000325 (stuff accumulating cell)
0000473 (defensive cell)
0000234 (phagocyte)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0000255 (eukaryotic cell)
0000576 (monocyte)
0000860 (classical monocyte)
0002057 (CD14-positive, CD16-negative classical monocyte)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
0000625 (experimental infection sample)
0000350 (experimentally modified sample)
0000631 (trehalose dimycolate (TDM) treatment sample)
0011444 (CD14-positive monocytes - treated with Trehalose dimycolate (TDM) sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)
CL:0002057 (CD14-positive, CD16-negative classical monocyte)