FF:11881-125C9: Difference between revisions
From FANTOM5_SSTAR
(Created page with "{{f5samples
|id=FF:11881-125C9
|name=CD14+ monocytes - treated with IFN + N-hexane, donor3
|sample_id=11881
|rna_tube_id=
|rna_box=125
|rna_position=C9
|sample_cell_lot...") |
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005007 | ||
| | |accession_numbers=CAGE;DRX008152;DRR009024;DRZ000449;DRZ001834;DRZ011799;DRZ013184 | ||
| | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000766,CL:0000219,CL:0000325,CL:0000473,CL:0000234,CL:0000738,CL:0002087,CL:0000255,CL:0000576,CL:0000860,CL:0002057 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001,FF:0000350,FF:0000629,FF:0011443 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr2:68592406..68592424,+!p1@PLEK!3.41!2582.07!PLEK;;chr16:85932760..85932775,+!p1@IRF8!3.03!1066.41!IRF8;;chr11:47400078..47400106,-!p1@SPI1!2.69!488.45!SPI1;;chr12:54778471..54778528,-!p1@ZNF385A!2.61!402.36!ZNF385A;;chr7:115670804..115670825,-!p1@TFEC!2.28!190.52!TFEC;;chr6:36355431..36355466,-!p1@ETV7!2.18!151.31!ETV7;;chr11:47399947..47399961,-!p3@SPI1!2.14!138.10!SPI1;;chr6:106534192..106534224,+!p1@PRDM1!2.06!308.59!PRDM1;;chr1:25256756..25256774,-!p1@RUNX3!2.04!198.19!RUNX3;;chr20:39317868..39317884,-!p1@MAFB!1.98!1041.69!MAFB;;chr11:64764435..64764449,-!p1@BATF2!1.96!123.18!BATF2;;chr5:131826457..131826514,-!p1@IRF1!1.95!3229.50!IRF1;;chr10:35484053..35484076,+!p1@CREM!1.89!185.41!CREM;;chr11:47400062..47400077,-!p2@SPI1!1.89!76.29!SPI1;;chr7:128577972..128578047,+!p1@IRF5!1.88!114.65!IRF5;;chr2:231084639..231084654,-!p2@SP110!1.87!118.06!SP110;;chr11:615942..615957,-!p1@IRF7!1.86!643.17!IRF7;;chr21:34442439..34442455,+!p1@OLIG1!1.86!70.75!OLIG1;;chr6:106534230..106534254,+!p2@PRDM1!1.84!164.95!PRDM1;;chr2:70142232..70142251,+!p1@MXD1!1.83!357.18!MXD1;;chr12:54778351..54778378,-!p6@ZNF385A!1.82!64.79!ZNF385A;;chr11:47400032..47400043,-!p5@SPI1!1.82!64.36!SPI1;;chr11:47399996..47400014,-!p4@SPI1!1.81!63.51!SPI1;;chr10:64576105..64576133,-!p1@EGR2!1.78!118.92!EGR2;;chr19:33793430..33793447,-!p1@CEBPA!1.75!222.06!CEBPA;;chr21:30671690..30671762,+!p2@BACH1!1.73!172.62!BACH1;;chr19:50432132..50432217,+!p2@ATF5!1.70!57.54!ATF5;;chr21:36260295..36260310,-!p3@RUNX1!1.69!76.72!RUNX1;;chr7:50344289..50344323,+!p1@IKZF1!1.68!46.46!IKZF1;;chr14:75988771..75988826,+!p1@BATF!1.65!57.11!BATF;;chr2:68592394..68592405,+!p2@PLEK!1.65!43.47!PLEK;;chr16:31885093..31885165,+!p1@ZNF267!1.63!606.52!ZNF267;;chr2:97202480..97202499,+!p1@ARID5A!1.62!395.11!ARID5A;;chr6:144385698..144385742,-!p2@PLAGL1!1.62!48.59!PLAGL1;;chr2:145277640..145277771,-!p1@ZEB2!1.60!494.85!ZEB2;;chr14:75988831..75988847,+!p2@BATF!1.59!37.51!BATF;;chr1:158985493..158985535,+!p4@IFI16!1.58!55.84!IFI16;;chr17:45810594..45810608,+!p1@TBX21!1.56!34.95!TBX21;;chr19:45971246..45971265,+!p1@FOSB!1.55!606.09!FOSB;;chr12:11802753..11802834,+!p2@ETV6!1.55!161.54!ETV6;;chr10:51572408..51572454,+!p3@NCOA4!1.54!187.97!NCOA4;;chr11:65430554..65430579,-!p3@RELA!1.54!83.97!RELA;;chr1:158979872..158979898,+!p3@IFI16!1.50!92.06!IFI16;;chr10:51572339..51572376,+!p4@NCOA4!1.50!67.77!NCOA4;;chrX:2418949..2419024,-!p1@DHRSX,p1@ZBED1!1.48!29.41!ZBED1;;chr21:30671235..30671253,+!p1@BACH1!1.47!348.23!BACH1;;chr21:36421535..36421610,-!p2@RUNX1!1.46!95.47!RUNX1;;chr11:615570..615721,-!p2@IRF7!1.46!54.13!IRF7;;chr11:47400045..47400060,-!p6@SPI1!1.46!27.70!SPI1;;chrX:129244454..129244488,-!p1@ELF4!1.45!190.10!ELF4;;chr11:65430535..65430549,-!p4@RELA!1.44!30.69!RELA;;chr12:48298765..48298783,-!p2@VDR!1.42!52.00!VDR;;chr12:72056800..72056834,+!p1@THAP2!1.42!33.67!THAP2;;chr4:185395590..185395627,-!p3@IRF2!1.41!30.69!IRF2;;chr2:231090471..231090504,+!p2@SP140!1.41!24.72!SP140;;chr2:145275162..145275202,-!p2@ZEB2!1.40!137.24!ZEB2;;chr12:56415246..56415286,+!p2@IKZF4!1.40!23.87!IKZF4;;chr6:391743..391759,+!p1@IRF4!1.40!23.87!IRF4;;chr1:212782094..212782109,+!p1@ATF3!1.39!618.88!ATF3;;chr19:45251395..45251432,+!p8@BCL3!1.39!23.44!BCL3;;chrX:129244430..129244442,-!p5@ELF4!1.39!23.44!ELF4;;chr16:79634624..79634642,-!p1@MAF!1.37!86.52!MAF;;chr12:54694758..54694805,-!p1@NFE2!1.36!26.43!NFE2;;chr11:47399920..47399931,-!p7@SPI1!1.35!21.31!SPI1;;chr21:30672433..30672464,+!p6@BACH1!1.35!21.31!BACH1;;chr3:187455486..187455504,-!p6@BCL6!1.35!21.31!BCL6;;chr7:28725740..28725778,+!p1@CREB5!1.34!181.15!CREB5;;chr2:70314240..70314256,+!p4@PCBP1!1.34!42.20!PCBP1;;chr12:48298785..48298828,-!p1@VDR!1.33!106.13!VDR;;chr9:110250697..110250738,-!p2@KLF4!1.33!23.87!KLF4;;chr7:150946376..150946389,-!p6@SMARCD3!1.33!20.46!SMARCD3;;chr3:187455529..187455544,-!p5@BCL6!1.33!20.46!BCL6;;chr1:25256439..25256476,-!p3@RUNX3!1.33!20.46!RUNX3;;chr9:110252035..110252057,-!p1@KLF4!1.32!307.31!KLF4;;chr12:72056749..72056767,+!p6@THAP2!1.31!21.31!THAP2;;chr17:38497662..38497713,+!p4@RARA!1.30!22.16!RARA;;chr2:231084820..231084836,-!p5@SP110!1.30!21.74!SP110;;chr4:185395633..185395651,-!p2@IRF2!1.29!29.41!IRF2;;chr2:231084659..231084721,-!p1@SP110!1.28!409.18!SP110;;chr19:45250948..45250998,+!p3@BCL3!1.28!44.75!BCL3;;chr18:3449720..3449749,+!p2@TGIF1!1.28!38.36!TGIF1;;chr2:231280954..231280965,+!p2@SP100!1.27!32.39!SP100;;chr1:221052776..221052799,+!p1@HLX!1.27!31.11!HLX;;chr6:106535598..106535637,+!p7@PRDM1!1.27!17.48!PRDM1;;chr10:31288370..31288393,-!p3@ZNF438!1.26!17.05!ZNF438;;chr12:72056773..72056796,+!p3@THAP2!1.25!21.74!THAP2;;chr2:238600998..238601013,+!p5@LRRFIP1!1.25!16.62!LRRFIP1;;chr13:41593425..41593480,-!p1@ELF1!1.24!103.15!ELF1;;chr14:35872453..35872485,-!p2@NFKBIA!1.24!40.07!NFKBIA;;chr19:13213662..13213686,-!p1@LYL1!1.24!24.29!LYL1;;chr3:187455680..187455700,-!p4@BCL6!1.24!16.20!BCL6;;chr10:31288398..31288455,-!p2@ZNF438!1.22!18.33!ZNF438;;chr12:56415287..56415300,+!p5@IKZF4!1.22!15.77!IKZF4;;chr7:17338266..17338282,+!p1@AHR!1.21!160.26!AHR;;chr19:45252008..45252024,+!p2@BCL3!1.21!50.29!BCL3;;chr4:106068026..106068084,+!p1@TET2!1.20!130.85!TET2;;chr3:39195037..39195069,-!p2@CSRNP1!1.20!90.79!CSRNP1;;chr1:8484007..8484061,-!p13@RERE!1.20!18.75!RERE;;chr6:126240463..126240489,+!p6@NCOA7!1.20!16.62!NCOA7;;chr1:158979922..158979933,+!p13@IFI16!1.20!14.92!IFI16;;chr16:3285119..3285133,-!p2@ZNF200!1.19!28.98!ZNF200;;chr1:221052733..221052749,+!p2@HLX!1.19!18.75!HLX;;chr2:231090433..231090469,+!p1@SP140!1.18!14.07!SP140;;chr6:36355486..36355497,-!p3@ETV7!1.18!14.07!ETV7;;chr19:19496539..19496576,+!p8@GATAD2A!1.17!24.29!GATAD2A;;chr3:187463179..187463201,-!p2@BCL6!1.16!55.41!BCL6;;chr8:116681123..116681143,-!p4@TRPS1!1.16!26.00!TRPS1;;chr16:89787973..89788001,+!p3@ZNF276!1.16!26.00!ZNF276;;chr4:103422499..103422632,+!p1@NFKB1!1.15!269.80!NFKB1;;chr6:15246200..15246214,+!p2@JARID2!1.15!35.80!JARID2;;chr16:79634595..79634620,-!p2@MAF!1.15!23.87!MAF;;chr20:56195474..56195506,-!p1@ZBP1!1.15!13.21!ZBP1;;chr10:35484090..35484104,+!p6@CREM!1.15!13.21!CREM;;chr11:2292226..2292270,-!p1@ASCL2!1.15!13.21!ASCL2;;chr3:107318352..107318392,+!p14@BBX!1.15!13.21!BBX;;chr12:96588279..96588299,+!p4@ELK3!1.14!60.10!ELK3;;chr17:38498402..38498445,+!p3@RARA!1.13!45.18!RARA;;chr14:74226747..74226779,-!p3@C14orf43!1.12!68.62!C14orf43;;chr6:126240380..126240430,+!p2@NCOA7!1.12!31.97!NCOA7;;chr8:71316428..71316459,-!p2@NCOA2!1.12!20.46!NCOA2;;chr20:48807351..48807384,+!p1@CEBPB!1.11!1216.45!CEBPB;;chr22:38597987..38598021,+!p2@MAFF!1.11!73.31!MAFF;;chr3:187455634..187455651,-!p7@BCL6!1.11!11.93!BCL6;;chr19:45251943..45252006,+!p1@BCL3!1.10!303.05!BCL3;;chr9:129567282..129567353,+!p1@ZBTB43!1.10!151.31!ZBTB43;;chr12:96588219..96588263,+!p2@ELK3!1.10!83.97!ELK3;;chr2:145277882..145277967,-!p3@ZEB2!1.10!20.03!ZEB2;;chr21:34442540..34442560,+!p2@OLIG1!1.10!11.51!OLIG1;;chr17:38498594..38498661,+!p2@RARA!1.09!38.36!RARA;;chr7:17338324..17338341,+!p3@AHR!1.09!37.93!AHR;;chr3:12329397..12329433,+!p2@PPARG!1.09!26.00!PPARG;;chr21:36260343..36260402,-!p6@RUNX1!1.09!18.33!RUNX1;;chr6:44233252..44233296,-!p1@NFKBIE!1.08!108.26!NFKBIE;;chr10:104155480..104155534,+!p2@NFKB2!1.08!72.46!NFKB2;;chr19:12721790..12721810,+!p2@ZNF791!1.08!30.26!ZNF791;;chr1:221053049..221053075,+!p3@HLX!1.08!19.18!HLX;;chr2:28618532..28618610,+!p4@FOSL2!1.08!18.75!FOSL2;;chr14:75745523..75745537,+!p1@FOS!1.07!1275.69!FOS;;chr14:74226961..74227020,-!p1@C14orf43!1.07!71.61!C14orf43;;chr2:238600933..238600985,+!p3@LRRFIP1!1.07!58.82!LRRFIP1;;chr12:54785074..54785122,-!p2@ZNF385A!1.07!16.62!ZNF385A;;chrX:153305787..153305807,-!p3@MECP2!1.07!10.66!MECP2;;chr12:56753869..56753930,-!p1@STAT2!1.05!451.37!STAT2;;chr3:170075436..170075520,+!p1@SKIL!1.05!223.34!SKIL;;chr10:3827371..3827386,-!p2@KLF6!1.05!87.80!KLF6;;chr18:3449618..3449634,+!p13@TGIF1!1.05!12.79!TGIF1;;chr21:34398234..34398250,+!p1@OLIG2!1.05!10.23!OLIG2;;chr12:96588368..96588394,+!p3@ELK3!1.04!27.28!ELK3;;chr9:3525727..3525828,-!p2@RFX3!1.04!26.00!RFX3;;chr4:185395191..185395226,-!p4@IRF2!1.04!14.07!IRF2;;chr19:45254529..45254561,+!p10@BCL3!1.04!13.64!BCL3;;chr14:35873947..35873965,-!p1@NFKBIA!1.03!618.03!NFKBIA;;chr14:24630465..24630531,+!p1@IRF9!1.03!373.37!IRF9;;chr3:107318229..107318239,+!p17@BBX!1.03!9.80!BBX;;chr1:158979792..158979814,+!p2@IFI16!1.02!92.06!IFI16;;chr10:104154246..104154347,+!p3@NFKB2!1.02!59.25!NFKB2;;chr1:158979851..158979865,+!p5@IFI16!1.02!21.31!IFI16;;chr12:54785054..54785072,-!p4@ZNF385A!1.02!10.66!ZNF385A;;chr20:48599506..48599526,+!p1@SNAI1!1.01!60.52!SNAI1;;chr12:124873852..124873881,-!p3@NCOR2!1.01!56.26!NCOR2;;chr2:157189180..157189290,-!p1@NR4A2!1.01!49.02!NR4A2;;chr3:37217736..37217753,-!p2@LRRFIP2!1.01!39.21!LRRFIP2;;chr10:35484804..35484902,+!p2@CREM!1.01!36.23!CREM;;chr2:185463247..185463263,+!p1@ZNF804A!1.01!16.62!ZNF804A;;chr12:11802932..11802949,+!p3@ETV6!1.01!16.20!ETV6;;chr7:150974206..150974255,-!p1@SMARCD3!0.99!56.69!SMARCD3;;chr19:42636586..42636607,-!p1@POU2F2!0.99!24.72!POU2F2;;chr5:142782823..142782854,-!p3@NR3C1!0.99!12.79!NR3C1;;chr21:36260980..36261011,-!p1@RUNX1!0.98!252.75!RUNX1;;chrX:106960285..106960299,-!p1@TSC22D3!0.98!236.55!TSC22D3;;chr5:172483347..172483407,+!p1@C5orf41!0.98!65.64!CREBRF;;chr8:116681150..116681164,-!p5@TRPS1!0.98!17.05!TRPS1;;chr2:70167296..70167306,+!p3@MXD1!0.98!13.21!MXD1;;chr2:191885737..191885750,-!p4@STAT1!0.98!8.52!STAT1;;chr7:50343634..50343717,+!p2@IKZF1!0.98!8.52!IKZF1;;chr1:158985686..158985719,+!p15@IFI16!0.98!8.52!IFI16;;chr21:36260325..36260341,-!p14@RUNX1!0.98!8.52!RUNX1;;chr8:116681194..116681214,-!p1@TRPS1!0.97!79.70!TRPS1;;chr2:70142189..70142223,+!p2@MXD1!0.97!61.38!MXD1;;chr2:61108695..61108753,+!p1@REL!0.97!58.82!REL;;chr14:35872962..35873025,-!p3@NFKBIA!0.97!21.31!NFKBIA;;chr7:99156393..99156433,+!p6@ZNF655!0.97!19.18!ZNF655;;chr20:47894569..47894799,-!p1@ZNFX1!0.96!222.06!ZNFX1;;chr7:139762641..139762768,-!p1@PARP12!0.96!113.80!PARP12;;chr4:26322267..26322334,+!p3@RBPJ!0.96!20.03!RBPJ;;c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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000222;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000234;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000576;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000763;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000766;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000860;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002193;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002390;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002405 | |||
|ffid_belonging_in_development=CL:0000049,CL:0000134,CL:0002057 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 67: | Line 41: | ||
|fonse_treatment=EFO:0000369,FF:0000629,FF:0011443,FF:11881-125C9 | |fonse_treatment=EFO:0000369,FF:0000629,FF:0011443,FF:11881-125C9 | ||
|fonse_treatment_closure=EFO:0000369,FF:0000629,FF:0011443,FF:11881-125C9 | |fonse_treatment_closure=EFO:0000369,FF:0000629,FF:0011443,FF:11881-125C9 | ||
|has_quality= | |||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520IFN%2520%252b%2520N-hexane%252c%2520donor3.CNhs13490.11881-125C9.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520IFN%2520%252b%2520N-hexane%252c%2520donor3.CNhs13490.11881-125C9.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520IFN%2520%252b%2520N-hexane%252c%2520donor3.CNhs13490.11881-125C9.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520IFN%2520%252b%2520N-hexane%252c%2520donor3.CNhs13490.11881-125C9.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520IFN%2520%252b%2520N-hexane%252c%2520donor3.CNhs13490.11881-125C9.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11881-125C9 | |||
|is_a=EFO:0002091;;FF:0011443 | |||
|is_obsolete= | |||
|library_id=CNhs13490 | |||
|library_id_phase_based=2:CNhs13490 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11881 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11881 | |||
|name=CD14+ monocytes - treated with IFN + N-hexane, donor3 | |||
|namespace= | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs13490,LSID1025,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
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| |||
|rna_box=125 | |||
|rna_catalog_number= | |||
|rna_concentration=0.60922 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number=D5-2 | |||
|rna_od260/230=1.43 | |||
|rna_od260/280=2.01 | |||
|rna_position=C9 | |||
|rna_rin=9.2 | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=125C9 | |||
|rna_weight_ug=2.74149 | |||
|sample_age=21 | |||
|sample_category=primary cells | |||
|sample_cell_catalog= | |||
|sample_cell_line= | |||
|sample_cell_lot= | |||
|sample_cell_type=monocyte | |||
|sample_collaboration=Christine Wells (University of Queensland) | |||
|sample_company= | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease= | |||
|sample_donor(cell lot)=donor3 | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.6176263170445e-274!GO:0005737;cytoplasm;1.03065230499158e-126!GO:0043227;membrane-bound organelle;2.42277106475407e-115!GO:0043231;intracellular membrane-bound organelle;5.54554006044635e-115!GO:0043226;organelle;5.55411599191135e-107!GO:0043229;intracellular organelle;4.02405632938282e-106!GO:0044444;cytoplasmic part;4.99615367152811e-83!GO:0044422;organelle part;5.77244765401429e-69!GO:0005515;protein binding;3.58048158421842e-68!GO:0044446;intracellular organelle part;2.02703054381035e-67!GO:0044237;cellular metabolic process;4.85500174246303e-67!GO:0044238;primary metabolic process;6.38121720991716e-65!GO:0043170;macromolecule metabolic process;1.94534114459709e-64!GO:0032991;macromolecular complex;1.13265365920988e-58!GO:0003723;RNA binding;8.84959985385312e-56!GO:0030529;ribonucleoprotein complex;6.37742151337624e-51!GO:0019538;protein metabolic process;8.90921016000876e-50!GO:0044260;cellular macromolecule metabolic process;1.69776053223543e-47!GO:0044267;cellular protein metabolic process;1.75568002459149e-47!GO:0044428;nuclear part;9.09311965504694e-47!GO:0005634;nucleus;1.77733914118027e-45!GO:0033036;macromolecule localization;1.6354747990571e-41!GO:0015031;protein transport;4.90192800670202e-40!GO:0045184;establishment of protein localization;5.00580149794383e-40!GO:0006412;translation;1.0200390355354e-39!GO:0043233;organelle lumen;3.9677308488179e-39!GO:0031974;membrane-enclosed lumen;3.9677308488179e-39!GO:0008104;protein localization;1.12119172172464e-38!GO:0005829;cytosol;3.15046732142972e-35!GO:0043283;biopolymer metabolic process;1.37765011261941e-34!GO:0031090;organelle membrane;1.8192614144808e-32!GO:0006396;RNA processing;3.78802104263622e-32!GO:0010467;gene expression;5.72832785760305e-32!GO:0016071;mRNA metabolic process;1.22212304329263e-31!GO:0006915;apoptosis;5.13745626731737e-30!GO:0012501;programmed cell death;5.41963504646985e-30!GO:0005739;mitochondrion;1.21746677821818e-29!GO:0031981;nuclear lumen;1.79996670425456e-29!GO:0043234;protein complex;1.87007383374843e-29!GO:0009059;macromolecule biosynthetic process;2.36325084273583e-29!GO:0008219;cell death;5.49025090749641e-29!GO:0016265;death;5.49025090749641e-29!GO:0008380;RNA splicing;6.50217069220476e-28!GO:0046907;intracellular transport;3.3027900321951e-27!GO:0006397;mRNA processing;3.48293515500908e-27!GO:0006886;intracellular protein transport;1.30561734589533e-26!GO:0044249;cellular biosynthetic process;1.6639417422159e-26!GO:0009058;biosynthetic process;2.17059363865322e-26!GO:0005840;ribosome;3.1421187457962e-26!GO:0016043;cellular component organization and biogenesis;2.83850043940566e-25!GO:0031967;organelle envelope;4.86448024722874e-25!GO:0031975;envelope;8.79693826970984e-25!GO:0003735;structural constituent of ribosome;5.30888596403439e-24!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.3008641131714e-23!GO:0033279;ribosomal subunit;1.85323661556303e-22!GO:0005830;cytosolic ribosome (sensu Eukaryota);2.07621763226647e-22!GO:0000166;nucleotide binding;1.07694715052881e-21!GO:0044429;mitochondrial part;3.14450159041987e-21!GO:0044445;cytosolic part;4.57657022688125e-21!GO:0051649;establishment of cellular localization;5.41198928293581e-21!GO:0005654;nucleoplasm;1.55386106485746e-20!GO:0051641;cellular localization;1.68014094392062e-20!GO:0005681;spliceosome;2.16525744336582e-20!GO:0008134;transcription factor binding;1.05960262626096e-19!GO:0042981;regulation of apoptosis;3.72784380037865e-19!GO:0043067;regulation of programmed cell death;7.69808171731662e-19!GO:0006512;ubiquitin cycle;9.53214969827099e-19!GO:0065003;macromolecular complex assembly;1.23958885273222e-18!GO:0043412;biopolymer modification;2.84998202154825e-18!GO:0044265;cellular macromolecule catabolic process;2.8884088636005e-18!GO:0016192;vesicle-mediated transport;1.34537211647114e-17!GO:0044451;nucleoplasm part;1.42336913099212e-17!GO:0007243;protein kinase cascade;2.51999984321198e-17!GO:0022613;ribonucleoprotein complex biogenesis and assembly;4.06237400857669e-17!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;7.662394533521e-17!GO:0016462;pyrophosphatase activity;7.93788308547859e-17!GO:0006464;protein modification process;8.04115588330766e-17!GO:0006119;oxidative phosphorylation;8.21962681035575e-17!GO:0016817;hydrolase activity, acting on acid anhydrides;9.94874420462167e-17!GO:0017111;nucleoside-triphosphatase activity;2.52942491380792e-16!GO:0032553;ribonucleotide binding;3.64638885748144e-16!GO:0032555;purine ribonucleotide binding;3.64638885748144e-16!GO:0043687;post-translational protein modification;4.86264962389997e-16!GO:0005740;mitochondrial envelope;7.42405217541857e-16!GO:0007249;I-kappaB kinase/NF-kappaB cascade;1.26074429597688e-15!GO:0017076;purine nucleotide binding;1.32778912352643e-15!GO:0048523;negative regulation of cellular process;1.57298760991347e-15!GO:0043285;biopolymer catabolic process;2.20969354274264e-15!GO:0048770;pigment granule;2.50959427939012e-15!GO:0042470;melanosome;2.50959427939012e-15!GO:0031966;mitochondrial membrane;2.65267037316552e-15!GO:0019941;modification-dependent protein catabolic process;3.36176881203126e-15!GO:0043632;modification-dependent macromolecule catabolic process;3.36176881203126e-15!GO:0051603;proteolysis involved in cellular protein catabolic process;4.49723812214996e-15!GO:0002376;immune system process;4.71697004669666e-15!GO:0044257;cellular protein catabolic process;5.36946115568427e-15!GO:0019866;organelle inner membrane;6.51408518342666e-15!GO:0006511;ubiquitin-dependent protein catabolic process;7.14185914040605e-15!GO:0022607;cellular component assembly;7.4935536088534e-15!GO:0022618;protein-RNA complex assembly;9.46984457118173e-15!GO:0009057;macromolecule catabolic process;1.29954220818566e-14!GO:0005773;vacuole;1.53435482423989e-14!GO:0016874;ligase activity;1.63165198373928e-14!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;2.74021111645822e-14!GO:0003676;nucleic acid binding;2.77552155164567e-14!GO:0016604;nuclear body;4.28494543665769e-14!GO:0006605;protein targeting;1.43966351022683e-13!GO:0016070;RNA metabolic process;1.61609900598611e-13!GO:0048519;negative regulation of biological process;1.88456296741632e-13!GO:0007242;intracellular signaling cascade;1.93211317007405e-13!GO:0044248;cellular catabolic process;2.46833632890273e-13!GO:0000323;lytic vacuole;3.67082283769827e-13!GO:0005764;lysosome;3.67082283769827e-13!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;5.77002731572138e-13!GO:0000502;proteasome complex (sensu Eukaryota);9.40012988413971e-13!GO:0006793;phosphorus metabolic process;2.18664991707252e-12!GO:0006796;phosphate metabolic process;2.18664991707252e-12!GO:0050794;regulation of cellular process;2.18664991707252e-12!GO:0005794;Golgi apparatus;2.71032469539702e-12!GO:0005743;mitochondrial inner membrane;2.75413330663126e-12!GO:0012505;endomembrane system;3.23654371184644e-12!GO:0015934;large ribosomal subunit;3.28994177852817e-12!GO:0006913;nucleocytoplasmic transport;4.17204518325503e-12!GO:0016607;nuclear speck;4.31345292038683e-12!GO:0044455;mitochondrial membrane part;4.31345292038683e-12!GO:0006457;protein folding;4.68937954043762e-12!GO:0043069;negative regulation of programmed cell death;5.05098816078733e-12!GO:0030163;protein catabolic process;5.3740960430426e-12!GO:0006996;organelle organization and biogenesis;5.44952347143618e-12!GO:0003712;transcription cofactor activity;5.54497942736366e-12!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);5.54523612154058e-12!GO:0006955;immune response;5.60671433612001e-12!GO:0043066;negative regulation of apoptosis;6.13428065411362e-12!GO:0051169;nuclear transport;7.27711078062998e-12!GO:0006950;response to stress;8.12232060773633e-12!GO:0005768;endosome;8.13348898102896e-12!GO:0009615;response to virus;9.1403381818905e-12!GO:0005524;ATP binding;1.02956604271125e-11!GO:0051246;regulation of protein metabolic process;1.17554768646624e-11!GO:0008135;translation factor activity, nucleic acid binding;1.1953164830246e-11!GO:0032559;adenyl ribonucleotide binding;2.27134670037958e-11!GO:0016310;phosphorylation;3.28284960833045e-11!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);3.6899320003387e-11!GO:0065009;regulation of a molecular function;4.09927576973415e-11!GO:0015935;small ribosomal subunit;4.13234943905261e-11!GO:0030554;adenyl nucleotide binding;8.75666786241988e-11!GO:0006366;transcription from RNA polymerase II promoter;2.05213275724029e-10!GO:0006259;DNA metabolic process;2.71132093093868e-10!GO:0003743;translation initiation factor activity;2.83454974218344e-10!GO:0008639;small protein conjugating enzyme activity;3.6005584535199e-10!GO:0016787;hydrolase activity;5.00699531981329e-10!GO:0051186;cofactor metabolic process;5.13498932696543e-10!GO:0006413;translational initiation;5.13498932696543e-10!GO:0019787;small conjugating protein ligase activity;5.34712823913291e-10!GO:0009967;positive regulation of signal transduction;5.59244454685296e-10!GO:0006446;regulation of translational initiation;6.7129255826632e-10!GO:0004842;ubiquitin-protein ligase activity;7.06706598781698e-10!GO:0006916;anti-apoptosis;8.55373921818456e-10!GO:0005746;mitochondrial respiratory chain;1.11274927298475e-09!GO:0051082;unfolded protein binding;1.22492103577301e-09!GO:0050789;regulation of biological process;1.76970319964318e-09!GO:0005635;nuclear envelope;2.51767670594085e-09!GO:0048522;positive regulation of cellular process;2.74983566488037e-09!GO:0048193;Golgi vesicle transport;2.81473960482924e-09!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;3.08085916000744e-09!GO:0006732;coenzyme metabolic process;3.30803710810444e-09!GO:0005730;nucleolus;4.14188519642019e-09!GO:0050136;NADH dehydrogenase (quinone) activity;4.18449794285159e-09!GO:0003954;NADH dehydrogenase activity;4.18449794285159e-09!GO:0008137;NADH dehydrogenase (ubiquinone) activity;4.18449794285159e-09!GO:0000398;nuclear mRNA splicing, via spliceosome;5.21161473252828e-09!GO:0000375;RNA splicing, via transesterification reactions;5.21161473252828e-09!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;5.21161473252828e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;6.22559460379391e-09!GO:0009607;response to biotic stimulus;7.63331494716202e-09!GO:0048518;positive regulation of biological process;8.59459416696987e-09!GO:0016887;ATPase activity;9.27834030205695e-09!GO:0031324;negative regulation of cellular metabolic process;9.50323192567084e-09!GO:0005783;endoplasmic reticulum;1.33670063986261e-08!GO:0009056;catabolic process;1.54703296385317e-08!GO:0016881;acid-amino acid ligase activity;1.69661238431099e-08!GO:0042623;ATPase activity, coupled;1.75663557309752e-08!GO:0015986;ATP synthesis coupled proton transport;1.80038932872223e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.80038932872223e-08!GO:0017038;protein import;1.90870943315664e-08!GO:0006417;regulation of translation;2.22179560192389e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;2.49350349827366e-08!GO:0016879;ligase activity, forming carbon-nitrogen bonds;2.61053531016444e-08!GO:0005770;late endosome;3.3810372543205e-08!GO:0019829;cation-transporting ATPase activity;3.41712732626838e-08!GO:0043065;positive regulation of apoptosis;3.57150030818936e-08!GO:0043068;positive regulation of programmed cell death;5.54277838827432e-08!GO:0016564;transcription repressor activity;5.8945165861036e-08!GO:0042775;organelle ATP synthesis coupled electron transport;6.08456889932227e-08!GO:0042773;ATP synthesis coupled electron transport;6.08456889932227e-08!GO:0009150;purine ribonucleotide metabolic process;6.28270211231946e-08!GO:0009259;ribonucleotide metabolic process;6.44170500284515e-08!GO:0009152;purine ribonucleotide biosynthetic process;6.47281250523354e-08!GO:0044453;nuclear membrane part;7.40213791575549e-08!GO:0065007;biological regulation;7.56908765311389e-08!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;8.10380305580086e-08!GO:0006163;purine nucleotide metabolic process;9.66951751465814e-08!GO:0006164;purine nucleotide biosynthetic process;1.12331041252141e-07!GO:0050790;regulation of catalytic activity;1.13263604320363e-07!GO:0030964;NADH dehydrogenase complex (quinone);1.13263604320363e-07!GO:0045271;respiratory chain complex I;1.13263604320363e-07!GO:0005747;mitochondrial respiratory chain complex I;1.13263604320363e-07!GO:0005525;GTP binding;1.28432270740164e-07!GO:0051170;nuclear import;1.36102808531843e-07!GO:0006754;ATP biosynthetic process;1.45461309949467e-07!GO:0006753;nucleoside phosphate metabolic process;1.45461309949467e-07!GO:0003924;GTPase activity;1.49743922369426e-07!GO:0051726;regulation of cell cycle;1.54738784877008e-07!GO:0003713;transcription coactivator activity;1.55029268837262e-07!GO:0009260;ribonucleotide biosynthetic process;1.60023113599402e-07!GO:0000074;regulation of progression through cell cycle;1.79869778944157e-07!GO:0009892;negative regulation of metabolic process;1.93903480656872e-07!GO:0006606;protein import into nucleus;2.08959820459093e-07!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.11955974861742e-07!GO:0031965;nuclear membrane;2.17316131995605e-07!GO:0006917;induction of apoptosis;2.30007156508354e-07!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;2.30233690371124e-07!GO:0008565;protein transporter activity;2.56829010261288e-07!GO:0012502;induction of programmed cell death;3.73429952582838e-07!GO:0007264;small GTPase mediated signal transduction;3.73663304830488e-07!GO:0009966;regulation of signal transduction;4.58023133952438e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;4.70179370948409e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;4.70179370948409e-07!GO:0007049;cell cycle;4.85051326671043e-07!GO:0005793;ER-Golgi intermediate compartment;4.97820476502169e-07!GO:0008047;enzyme activator activity;5.04241873100556e-07!GO:0015078;hydrogen ion transmembrane transporter activity;5.21116600586574e-07!GO:0016481;negative regulation of transcription;5.43993477472016e-07!GO:0005774;vacuolar membrane;5.4854344302628e-07!GO:0046034;ATP metabolic process;6.27262549528583e-07!GO:0009142;nucleoside triphosphate biosynthetic process;6.28797679102443e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;6.28797679102443e-07!GO:0048468;cell development;7.22418267637665e-07!GO:0009055;electron carrier activity;7.27604827279813e-07!GO:0016469;proton-transporting two-sector ATPase complex;7.35264045288566e-07!GO:0004386;helicase activity;7.62107221206995e-07!GO:0044440;endosomal part;7.92483026666982e-07!GO:0010008;endosome membrane;7.92483026666982e-07!GO:0031980;mitochondrial lumen;7.92483026666982e-07!GO:0005759;mitochondrial matrix;7.92483026666982e-07!GO:0045786;negative regulation of progression through cell cycle;7.97706183703542e-07!GO:0043228;non-membrane-bound organelle;8.00939786150057e-07!GO:0043232;intracellular non-membrane-bound organelle;8.00939786150057e-07!GO:0044432;endoplasmic reticulum part;8.8446120241324e-07!GO:0031326;regulation of cellular biosynthetic process;9.87638771463228e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.03985574858726e-06!GO:0009144;purine nucleoside triphosphate metabolic process;1.03985574858726e-06!GO:0006752;group transfer coenzyme metabolic process;1.06508830773519e-06!GO:0019899;enzyme binding;1.19509910552595e-06!GO:0050657;nucleic acid transport;1.27394658044396e-06!GO:0051236;establishment of RNA localization;1.27394658044396e-06!GO:0050658;RNA transport;1.27394658044396e-06!GO:0009889;regulation of biosynthetic process;1.2909528662186e-06!GO:0009199;ribonucleoside triphosphate metabolic process;1.30989776010538e-06!GO:0005839;proteasome core complex (sensu Eukaryota);1.37965048005126e-06!GO:0009108;coenzyme biosynthetic process;1.72887155484944e-06!GO:0051188;cofactor biosynthetic process;1.77639129247163e-06!GO:0006403;RNA localization;1.82888882035116e-06!GO:0006974;response to DNA damage stimulus;1.83835863481193e-06!GO:0008026;ATP-dependent helicase activity;2.0092989892622e-06!GO:0044437;vacuolar part;2.19977243623999e-06!GO:0016044;membrane organization and biogenesis;2.35221286003269e-06!GO:0032561;guanyl ribonucleotide binding;2.56258779119665e-06!GO:0019001;guanyl nucleotide binding;2.56258779119665e-06!GO:0009141;nucleoside triphosphate metabolic process;2.71874177683401e-06!GO:0019222;regulation of metabolic process;2.74494103196353e-06!GO:0032446;protein modification by small protein conjugation;3.56447057481814e-06!GO:0005765;lysosomal membrane;3.64323411094818e-06!GO:0005643;nuclear pore;3.93312201881622e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;4.10189865322472e-06!GO:0006461;protein complex assembly;4.87820105409789e-06!GO:0016568;chromatin modification;5.44868673731264e-06!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;6.038162874821e-06!GO:0015399;primary active transmembrane transporter activity;6.038162874821e-06!GO:0016567;protein ubiquitination;7.13992461317256e-06!GO:0004298;threonine endopeptidase activity;7.23198083032125e-06!GO:0043566;structure-specific DNA binding;7.74199332391379e-06!GO:0016563;transcription activator activity;8.08076019299377e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;8.99620963627319e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;8.99984494924564e-06!GO:0003714;transcription corepressor activity;9.94337461382222e-06!GO:0006888;ER to Golgi vesicle-mediated transport;1.07891288662996e-05!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.25143084045151e-05!GO:0016197;endosome transport;1.31981177851972e-05!GO:0005789;endoplasmic reticulum membrane;1.44227758360378e-05!GO:0003724;RNA helicase activity;1.5679720921512e-05!GO:0006954;inflammatory response;1.61069778142979e-05!GO:0051028;mRNA transport;1.62650405617739e-05!GO:0031252;leading edge;1.75996798051764e-05!GO:0006325;establishment and/or maintenance of chromatin architecture;1.81829712401074e-05!GO:0031982;vesicle;2.25030488655943e-05!GO:0046930;pore complex;3.21031674748317e-05!GO:0005096;GTPase activator activity;3.49123890475549e-05!GO:0003697;single-stranded DNA binding;3.51932726733407e-05!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;3.64050289977803e-05!GO:0006323;DNA packaging;4.21345646378277e-05!GO:0006401;RNA catabolic process;4.61990229938041e-05!GO:0030695;GTPase regulator activity;5.57899807980382e-05!GO:0048475;coated membrane;5.79695465839014e-05!GO:0030117;membrane coat;5.79695465839014e-05!GO:0030120;vesicle coat;6.25492986461149e-05!GO:0030662;coated vesicle membrane;6.25492986461149e-05!GO:0051336;regulation of hydrolase activity;6.25720005153805e-05!GO:0043492;ATPase activity, coupled to movement of substances;6.2871911091146e-05!GO:0051789;response to protein stimulus;6.3121886088778e-05!GO:0006986;response to unfolded protein;6.3121886088778e-05!GO:0006281;DNA repair;6.69737255834865e-05!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;7.58656861973906e-05!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;8.82311336262758e-05!GO:0051707;response to other organism;8.82311336262758e-05!GO:0065002;intracellular protein transport across a membrane;8.84955079454908e-05!GO:0005769;early endosome;9.0257753837318e-05!GO:0009060;aerobic respiration;9.81894860054943e-05!GO:0001816;cytokine production;9.83693015278597e-05!GO:0006613;cotranslational protein targeting to membrane;9.94790202769445e-05!GO:0045259;proton-transporting ATP synthase complex;0.000105742460257539!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000106352134009868!GO:0004674;protein serine/threonine kinase activity;0.000108133885713504!GO:0008234;cysteine-type peptidase activity;0.000115746292365098!GO:0030099;myeloid cell differentiation;0.000119867527456209!GO:0031902;late endosome membrane;0.000119867527456209!GO:0006897;endocytosis;0.000119867527456209!GO:0010324;membrane invagination;0.000119867527456209!GO:0000245;spliceosome assembly;0.000129141671342329!GO:0031410;cytoplasmic vesicle;0.000141755721922448!GO:0000151;ubiquitin ligase complex;0.000141755721922448!GO:0051168;nuclear export;0.000147132298705918!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000163780734036166!GO:0030532;small nuclear ribonucleoprotein complex;0.000166038406162664!GO:0005083;small GTPase regulator activity;0.000167882908351469!GO:0031323;regulation of cellular metabolic process;0.00017498103980655!GO:0022402;cell cycle process;0.000175152331238824!GO:0044431;Golgi apparatus part;0.000176111120746704!GO:0031202;RNA splicing factor activity, transesterification mechanism;0.000186619114320555!GO:0016740;transferase activity;0.000188498725911357!GO:0042254;ribosome biogenesis and assembly;0.000214778344562363!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;0.00021651734817096!GO:0006402;mRNA catabolic process;0.000218256672408346!GO:0008632;apoptotic program;0.000227491514019517!GO:0005057;receptor signaling protein activity;0.000236441195316473!GO:0008186;RNA-dependent ATPase activity;0.000249624162234099!GO:0005885;Arp2/3 protein complex;0.00025541660179468!GO:0006818;hydrogen transport;0.000258383497577328!GO:0032940;secretion by cell;0.000279956695908925!GO:0031988;membrane-bound vesicle;0.000303108265760884!GO:0007265;Ras protein signal transduction;0.000304280097642196!GO:0030097;hemopoiesis;0.000341641393280555!GO:0005761;mitochondrial ribosome;0.000356307938744618!GO:0000313;organellar ribosome;0.000356307938744618!GO:0005667;transcription factor complex;0.000387518742820158!GO:0015992;proton transport;0.000387679014417079!GO:0005798;Golgi-associated vesicle;0.000390353913834149!GO:0046983;protein dimerization activity;0.00040155975002129!GO:0046822;regulation of nucleocytoplasmic transport;0.000419570927719655!GO:0051276;chromosome organization and biogenesis;0.000432914839236579!GO:0045892;negative regulation of transcription, DNA-dependent;0.000440970509360376!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000452137120333628!GO:0007034;vacuolar transport;0.000470444238048124!GO:0009719;response to endogenous stimulus;0.000527465787754284!GO:0022890;inorganic cation transmembrane transporter activity;0.000610299352169137!GO:0007259;JAK-STAT cascade;0.000613019594211334!GO:0007050;cell cycle arrest;0.00062940887608528!GO:0045333;cellular respiration;0.00063660531722626!GO:0001726;ruffle;0.000651842198818653!GO:0007005;mitochondrion organization and biogenesis;0.000652044548032152!GO:0051427;hormone receptor binding;0.000679941142472713!GO:0004004;ATP-dependent RNA helicase activity;0.000718283643418835!GO:0009893;positive regulation of metabolic process;0.00072971031755039!GO:0006612;protein targeting to membrane;0.000732718981077716!GO:0006952;defense response;0.000748963752712156!GO:0007041;lysosomal transport;0.000770959157867755!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;0.000807521060002326!GO:0004812;aminoacyl-tRNA ligase activity;0.000807521060002326!GO:0016875;ligase activity, forming carbon-oxygen bonds;0.000807521060002326!GO:0005637;nuclear inner membrane;0.000888023486934526!GO:0008654;phospholipid biosynthetic process;0.000902674643449918!GO:0007040;lysosome organization and biogenesis;0.000910714159705608!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.000919136108593174!GO:0016023;cytoplasmic membrane-bound vesicle;0.000921113844271394!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000921113844271394!GO:0003729;mRNA binding;0.00101359794186997!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.00102499872772882!GO:0018193;peptidyl-amino acid modification;0.00102695702420645!GO:0045321;leukocyte activation;0.00104409838578645!GO:0035257;nuclear hormone receptor binding;0.00109610896223083!GO:0051090;regulation of transcription factor activity;0.00111115582748487!GO:0016301;kinase activity;0.00117843300505911!GO:0005099;Ras GTPase activator activity;0.00118350172641711!GO:0043087;regulation of GTPase activity;0.00119941748043405!GO:0051338;regulation of transferase activity;0.00127344100537042!GO:0046519;sphingoid metabolic process;0.0013659251112082!GO:0010468;regulation of gene expression;0.00137303945857778!GO:0009117;nucleotide metabolic process;0.00142006348714456!GO:0043038;amino acid activation;0.00142740207942007!GO:0006418;tRNA aminoacylation for protein translation;0.00142740207942007!GO:0043039;tRNA aminoacylation;0.00142740207942007!GO:0051223;regulation of protein transport;0.00145449132937198!GO:0019221;cytokine and chemokine mediated signaling pathway;0.00147546548464215!GO:0002757;immune response-activating signal transduction;0.0016921577662666!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.00174482466321085!GO:0044262;cellular carbohydrate metabolic process;0.00180613790490836!GO:0043549;regulation of kinase activity;0.00203500728007457!GO:0006468;protein amino acid phosphorylation;0.00204879464272471!GO:0002252;immune effector process;0.00207722620257059!GO:0007033;vacuole organization and biogenesis;0.00217527242743739!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00218128415420519!GO:0030036;actin cytoskeleton organization and biogenesis;0.00218128415420519!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00218580978257603!GO:0033157;regulation of intracellular protein transport;0.00219737926259296!GO:0042306;regulation of protein import into nucleus;0.00219737926259296!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00234027515038594!GO:0006672;ceramide metabolic process;0.00238867820973719!GO:0051187;cofactor catabolic process;0.00244429646282592!GO:0006099;tricarboxylic acid cycle;0.0025076713093011!GO:0046356;acetyl-CoA catabolic process;0.0025076713093011!GO:0006399;tRNA metabolic process;0.00252667972133202!GO:0030149;sphingolipid catabolic process;0.00256179637846863!GO:0002274;myeloid leukocyte activation;0.00260445886983531!GO:0022415;viral reproductive process;0.00268226085623024!GO:0043623;cellular protein complex assembly;0.00268226085623024!GO:0045859;regulation of protein kinase activity;0.00283978802507183!GO:0016363;nuclear matrix;0.00296184163710209!GO:0033116;ER-Golgi intermediate compartment membrane;0.00309155647997486!GO:0002764;immune response-regulating signal transduction;0.0035079741138431!GO:0003690;double-stranded DNA binding;0.00352658451420438!GO:0002520;immune system development;0.00370003956492515!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00381160687529377!GO:0006643;membrane lipid metabolic process;0.00396741135746456!GO:0004197;cysteine-type endopeptidase activity;0.00408258218806963!GO:0000139;Golgi membrane;0.00409363586625523!GO:0016072;rRNA metabolic process;0.00419564221305688!GO:0016779;nucleotidyltransferase activity;0.00422012144372678!GO:0005741;mitochondrial outer membrane;0.00434200201930558!GO:0045941;positive regulation of transcription;0.00437888551527858!GO:0045637;regulation of myeloid cell differentiation;0.00451029150060159!GO:0031072;heat shock protein binding;0.00454634739254054!GO:0002250;adaptive immune response;0.00454634739254054!GO:0002460;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.00454634739254054!GO:0006919;caspase activation;0.00454634739254054!GO:0006364;rRNA processing;0.00458905881806295!GO:0009611;response to wounding;0.00468348783080096!GO:0006091;generation of precursor metabolites and energy;0.00490125461328588!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.00503765738640619!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00503765738640619!GO:0006084;acetyl-CoA metabolic process;0.00504233376181692!GO:0031901;early endosome membrane;0.0050551601101574!GO:0045893;positive regulation of transcription, DNA-dependent;0.005144463978042!GO:0031325;positive regulation of cellular metabolic process;0.00517715205089326!GO:0060090;molecular adaptor activity;0.00527193684912408!GO:0043021;ribonucleoprotein binding;0.00561187443027111!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00570968126434177!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00570968126434177!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00570968126434177!GO:0048534;hemopoietic or lymphoid organ development;0.00574167828772685!GO:0043281;regulation of caspase activity;0.00574167828772685!GO:0045454;cell redox homeostasis;0.00578070020550603!GO:0006607;NLS-bearing substrate import into nucleus;0.00583827525485733!GO:0016251;general RNA polymerase II transcription factor activity;0.00589562181570011!GO:0042990;regulation of transcription factor import into nucleus;0.00591223934338331!GO:0042991;transcription factor import into nucleus;0.00591223934338331!GO:0006458;'de novo' protein folding;0.00607111090052945!GO:0051084;'de novo' posttranslational protein folding;0.00607111090052945!GO:0043433;negative regulation of transcription factor activity;0.00612995863413694!GO:0001817;regulation of cytokine production;0.00614233070946838!GO:0045045;secretory pathway;0.00631425268729101!GO:0006891;intra-Golgi vesicle-mediated transport;0.00632090858378519!GO:0048487;beta-tubulin binding;0.0065051223731303!GO:0003725;double-stranded RNA binding;0.0065221361974907!GO:0009109;coenzyme catabolic process;0.00656713848560149!GO:0042110;T cell activation;0.00690945437628728!GO:0043280;positive regulation of caspase activity;0.00699253409095444!GO:0006350;transcription;0.00730377578686815!GO:0032318;regulation of Ras GTPase activity;0.00779786166808849!GO:0043085;positive regulation of catalytic activity;0.00811264485059072!GO:0030041;actin filament polymerization;0.00813892753173091!GO:0004185;serine carboxypeptidase activity;0.00844382160427651!GO:0002440;production of molecular mediator of immune response;0.00853896350458999!GO:0002429;immune response-activating cell surface receptor signaling pathway;0.00858465955211997!GO:0006414;translational elongation;0.0087977002715846!GO:0008383;manganese superoxide dismutase activity;0.00969595001042368!GO:0001315;age-dependent response to reactive oxygen species;0.00969595001042368!GO:0005813;centrosome;0.00974183349926837!GO:0002521;leukocyte differentiation;0.00975897939654225!GO:0030693;caspase activity;0.0101533943070263!GO:0032386;regulation of intracellular transport;0.0104442449701831!GO:0030176;integral to endoplasmic reticulum membrane;0.0104442449701831!GO:0048500;signal recognition particle;0.0104681260742126!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.0104681260742126!GO:0000287;magnesium ion binding;0.0105250724815898!GO:0031968;organelle outer membrane;0.0106704864345202!GO:0030127;COPII vesicle coat;0.0109123647480353!GO:0012507;ER to Golgi transport vesicle membrane;0.0109123647480353!GO:0019867;outer membrane;0.0109123647480353!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0112396236466067!GO:0030867;rough endoplasmic reticulum membrane;0.0114720703723269!GO:0031625;ubiquitin protein ligase binding;0.0115254056001654!GO:0046966;thyroid hormone receptor binding;0.0115999663889541!GO:0002822;regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.;0.0117188627627575!GO:0002819;regulation of adaptive immune response;0.0117188627627575!GO:0030134;ER to Golgi transport vesicle;0.0118327169843286!GO:0006352;transcription initiation;0.0118379827330852!GO:0042802;identical protein binding;0.0123807185333845!GO:0030218;erythrocyte differentiation;0.0130513242210216!GO:0005484;SNAP receptor activity;0.013394623947958!GO:0030029;actin filament-based process;0.0135241836058282!GO:0002467;germinal center formation;0.0137082244914533!GO:0009165;nucleotide biosynthetic process;0.0137146051591097!GO:0002682;regulation of immune system process;0.0139265573713038!GO:0051252;regulation of RNA metabolic process;0.014148745487652!GO:0046649;lymphocyte activation;0.0146779101704889!GO:0002443;leukocyte mediated immunity;0.0146842423604544!GO:0051092;activation of NF-kappaB transcription factor;0.0148932556099727!GO:0019377;glycolipid catabolic process;0.0148975506074443!GO:0002684;positive regulation of immune system process;0.0148975506074443!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0149875237703255!GO:0030027;lamellipodium;0.0155127374543676!GO:0065004;protein-DNA complex assembly;0.0157712902388572!GO:0004177;aminopeptidase activity;0.0157712902388572!GO:0002768;immune response-regulating cell surface receptor signaling pathway;0.0158366775509161!GO:0032763;regulation of mast cell cytokine production;0.0161913302691246!GO:0032762;mast cell cytokine production;0.0161913302691246!GO:0030384;phosphoinositide metabolic process;0.0164271886183421!GO:0030224;monocyte differentiation;0.0164641422315542!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.016536582695513!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0170624925238128!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0170839947898665!GO:0045047;protein targeting to ER;0.0170839947898665!GO:0019883;antigen processing and presentation of endogenous antigen;0.0172544365825639!GO:0030658;transport vesicle membrane;0.0177925398424153!GO:0030518;steroid hormone receptor signaling pathway;0.018093169758599!GO:0051098;regulation of binding;0.0183013597861086!GO:0030258;lipid modification;0.0187385271902189!GO:0051085;chaperone cofactor-dependent protein folding;0.0189620269261977!GO:0046979;TAP2 binding;0.0189620269261977!GO:0046977;TAP binding;0.0189620269261977!GO:0046978;TAP1 binding;0.0189620269261977!GO:0019318;hexose metabolic process;0.0194183594303513!GO:0048002;antigen processing and presentation of peptide antigen;0.0195808408398199!GO:0048471;perinuclear region of cytoplasm;0.0196432276251634!GO:0008624;induction of apoptosis by extracellular signals;0.0197328907916745!GO:0051059;NF-kappaB binding;0.0201052633797136!GO:0001819;positive regulation of cytokine production;0.020185046151215!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0206935304880353!GO:0006650;glycerophospholipid metabolic process;0.0207966753994328!GO:0050778;positive regulation of immune response;0.0208410413545407!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0209161081588403!GO:0043071;positive regulation of non-apoptotic programmed cell death;0.0210226833750033!GO:0000209;protein polyubiquitination;0.0213405263807688!GO:0019904;protein domain specific binding;0.0217043256303!GO:0006611;protein export from nucleus;0.0217433017541919!GO:0002224;toll-like receptor signaling pathway;0.021883613188037!GO:0002221;pattern recognition receptor signaling pathway;0.021883613188037!GO:0002253;activation of immune response;0.0219074144139617!GO:0005815;microtubule organizing center;0.0219235070746098!GO:0008637;apoptotic mitochondrial changes;0.0220889673419525!GO:0017091;AU-rich element binding;0.0221454767846362!GO:0050779;RNA destabilization;0.0221454767846362!GO:0000289;poly(A) tail shortening;0.0221454767846362!GO:0003702;RNA polymerase II transcription factor activity;0.0225973813478203!GO:0008139;nuclear localization sequence binding;0.022883152350608!GO:0019882;antigen processing and presentation;0.022883152350608!GO:0015923;mannosidase activity;0.022883152350608!GO:0050811;GABA receptor binding;0.022883152350608!GO:0033367;protein localization in mast cell secretory granule;0.022883152350608!GO:0033365;protein localization in organelle;0.022883152350608!GO:0033371;T cell secretory granule organization and biogenesis;0.022883152350608!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.022883152350608!GO:0033375;protease localization in T cell secretory granule;0.022883152350608!GO:0042629;mast cell granule;0.022883152350608!GO:0033377;maintenance of protein localization in T cell secretory granule;0.022883152350608!GO:0033364;mast cell secretory granule organization and biogenesis;0.022883152350608!GO:0033380;granzyme B localization in T cell secretory granule;0.022883152350608!GO:0033379;maintenance of protease localization in T cell secretory granule;0.022883152350608!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.022883152350608!GO:0033368;protease localization in mast cell secretory granule;0.022883152350608!GO:0033366;protein localization in secretory granule;0.022883152350608!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.022883152350608!GO:0033374;protein localization in T cell secretory granule;0.022883152350608!GO:0006405;RNA export from nucleus;0.0229238033529648!GO:0015631;tubulin binding;0.0230312332078238!GO:0005048;signal sequence binding;0.0230531905882948!GO:0001775;cell activation;0.0231175566811985!GO:0019210;kinase inhibitor activity;0.0231340196884336!GO:0046466;membrane lipid catabolic process;0.0232121203523816!GO:0016791;phosphoric monoester hydrolase activity;0.0232137914241494!GO:0004860;protein kinase inhibitor activity;0.0234360991589365!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0236142891123092!GO:0000049;tRNA binding;0.023635016951491!GO:0006516;glycoprotein catabolic process;0.023864691940667!GO:0030137;COPI-coated vesicle;0.0240155709334165!GO:0005996;monosaccharide metabolic process;0.02409575008533!GO:0030663;COPI coated vesicle membrane;0.02409575008533!GO:0030126;COPI vesicle coat;0.02409575008533!GO:0033673;negative regulation of kinase activity;0.0247575452816322!GO:0006469;negative regulation of protein kinase activity;0.0247575452816322!GO:0046578;regulation of Ras protein signal transduction;0.0257143707952585!GO:0046467;membrane lipid biosynthetic process;0.0258583975650907!GO:0019783;small conjugating protein-specific protease activity;0.0264525424066409!GO:0017166;vinculin binding;0.0267892066945603!GO:0008312;7S RNA binding;0.0268085998927927!GO:0002697;regulation of immune effector process;0.0269394238267766!GO:0043300;regulation of leukocyte degranulation;0.0270294829873217!GO:0051345;positive regulation of hydrolase activity;0.0270294829873217!GO:0002237;response to molecule of bacterial origin;0.0270762470526722!GO:0050851;antigen receptor-mediated signaling pathway;0.0270762470526722!GO:0030133;transport vesicle;0.0277763786551413!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0278374409982618!GO:0015036;disulfide oxidoreductase activity;0.0284269651427174!GO:0050900;leukocyte migration;0.0286982746878205!GO:0045113;regulation of integrin biosynthetic process;0.0290146228083979!GO:0045112;integrin biosynthetic process;0.0290146228083979!GO:0050776;regulation of immune response;0.0293300105402377!GO:0003727;single-stranded RNA binding;0.0293300105402377!GO:0030433;ER-associated protein catabolic process;0.0295582569957876!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0295582569957876!GO:0002444;myeloid leukocyte mediated immunity;0.0299910570577249!GO:0051101;regulation of DNA binding;0.0300431780073796!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0303257205688684!GO:0051247;positive regulation of protein metabolic process;0.0304904428785393!GO:0045792;negative regulation of cell size;0.0306225934689861!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0307486744062687!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0307486744062687!GO:0051091;positive regulation of transcription factor activity;0.0307953185809446!GO:0004843;ubiquitin-specific protease activity;0.0319118600134073!GO:0051348;negative regulation of transferase activity;0.0319118600134073!GO:0046426;negative regulation of JAK-STAT cascade;0.0319118600134073!GO:0007162;negative regulation of cell adhesion;0.0319118600134073!GO:0043488;regulation of mRNA stability;0.0319118600134073!GO:0043487;regulation of RNA stability;0.0319118600134073!GO:0005669;transcription factor TFIID complex;0.0319118600134073!GO:0006665;sphingolipid metabolic process;0.0321881219492367!GO:0005070;SH3/SH2 adaptor activity;0.0325355659902295!GO:0042613;MHC class II protein complex;0.0325355659902295!GO:0005905;coated pit;0.0327885161941041!GO:0032760;positive regulation of tumor necrosis factor production;0.0330961927280221!GO:0019079;viral genome replication;0.0332342695198491!GO:0002718;regulation of cytokine production during immune response;0.0332942179876137!GO:0002367;cytokine production during immune response;0.0332942179876137!GO:0002700;regulation of production of molecular mediator of immune response;0.0332942179876137!GO:0043621;protein self-association;0.0332942179876137!GO:0008629;induction of apoptosis by intracellular signals;0.033530788793749!GO:0000118;histone deacetylase complex;0.0336480557247175!GO:0046479;glycosphingolipid catabolic process;0.0336480557247175!GO:0006354;RNA elongation;0.0336480557247175!GO:0030660;Golgi-associated vesicle membrane;0.033665535250027!GO:0008286;insulin receptor signaling pathway;0.033763830811705!GO:0030100;regulation of endocytosis;0.0346425017401292!GO:0043022;ribosome binding;0.0347701993820362!GO:0005869;dynactin complex;0.0349222927269725!GO:0030308;negative regulation of cell growth;0.0362415794698184!GO:0005694;chromosome;0.0365566884967065!GO:0006007;glucose catabolic process;0.0366948799119989!GO:0003711;transcription elongation regulator activity;0.0367908104124883!GO:0006644;phospholipid metabolic process;0.0368302058948386!GO:0005684;U2-dependent spliceosome;0.0371478705475635!GO:0030833;regulation of actin filament polymerization;0.0373309465798154!GO:0033033;negative regulation of myeloid cell apoptosis;0.0373309465798154!GO:0001803;regulation of type III hypersensitivity;0.0373309465798154!GO:0032733;positive regulation of interleukin-10 production;0.0373309465798154!GO:0033025;regulation of mast cell apoptosis;0.0373309465798154!GO:0001805;positive regulation of type III hypersensitivity;0.0373309465798154!GO:0033023;mast cell homeostasis;0.0373309465798154!GO:0002431;Fc receptor mediated stimulatory signaling pathway;0.0373309465798154!GO:0033032;regulation of myeloid cell apoptosis;0.0373309465798154!GO:0001802;type III hypersensitivity;0.0373309465798154!GO:0033028;myeloid cell apoptosis;0.0373309465798154!GO:0042590;antigen processing and presentation of exogenous peptide antigen via MHC class I;0.0373309465798154!GO:0033026;negative regulation of mast cell apoptosis;0.0373309465798154!GO:0033024;mast cell apoptosis;0.0373309465798154!GO:0008656;caspase activator activity;0.0377369071685882!GO:0051540;metal cluster binding;0.0379639308890938!GO:0051536;iron-sulfur cluster binding;0.0379639308890938!GO:0006260;DNA replication;0.0380110239111628!GO:0030521;androgen receptor signaling pathway;0.0382536555545899!GO:0008538;proteasome activator activity;0.0386656628193728!GO:0046483;heterocycle metabolic process;0.0388350850549708!GO:0030118;clathrin coat;0.0390672782356213!GO:0006749;glutathione metabolic process;0.0390678332544545!GO:0002824;positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.04054103561214!GO:0002821;positive regulation of adaptive immune response;0.04054103561214!GO:0008287;protein serine/threonine phosphatase complex;0.0410216918770922!GO:0000785;chromatin;0.041223314179236!GO:0006509;membrane protein ectodomain proteolysis;0.041223314179236!GO:0033619;membrane protein proteolysis;0.041223314179236!GO:0051235;maintenance of localization;0.0414619070511073!GO:0042108;positive regulation of cytokine biosynthetic process;0.0421674488236957!GO:0047485;protein N-terminus binding;0.0426381055543357!GO:0016491;oxidoreductase activity;0.042678653665631!GO:0006376;mRNA splice site selection;0.0429236588868866!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0429236588868866!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0433432042295013!GO:0003746;translation elongation factor activity;0.0437880422211261!GO:0048146;positive regulation of fibroblast proliferation;0.0443793985835411!GO:0000738;DNA catabolic process, exonucleolytic;0.0447159651137797!GO:0000082;G1/S transition of mitotic cell cycle;0.0452749548725858!GO:0006914;autophagy;0.0452749548725858!GO:0019220;regulation of phosphate metabolic process;0.0455450472910882!GO:0051174;regulation of phosphorus metabolic process;0.0455450472910882!GO:0006465;signal peptide processing;0.0455450472910882!GO:0006333;chromatin assembly or disassembly;0.0455450472910882!GO:0030503;regulation of cell redox homeostasis;0.047291635126023!GO:0000339;RNA cap binding;0.047291635126023!GO:0051056;regulation of small GTPase mediated signal transduction;0.0472949191685394!GO:0005975;carbohydrate metabolic process;0.0475658473621752!GO:0051087;chaperone binding;0.0478398011636055!GO:0045309;protein phosphorylated amino acid binding;0.0485124238139036!GO:0051049;regulation of transport;0.0485124238139036!GO:0008361;regulation of cell size;0.0486376782058492!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0487644707821702!GO:0045576;mast cell activation;0.0495485034757039!GO:0019843;rRNA binding;0.0498817289614434 | |||
|sample_id=11881 | |||
|sample_note= | |||
|sample_sex=female | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue= | |||
|top_motifs=STAT2,4,6:5.11984081227;STAT1,3:4.46933375631;IRF7:4.19187455534;IRF1,2:3.753367067;STAT5{A,B}:3.20571163191;CEBPA,B_DDIT3:3.11980719592;EP300:2.92177581893;SPIB:2.73823543167;SPI1:2.61376481887;NFE2L2:2.60203836357;NANOG{mouse}:2.5134441175;NFE2:2.45252553549;PAX2:2.40151406391;FOSL2:2.37672951723;ETS1,2:2.19518831452;FOXN1:2.19422831478;SREBF1,2:2.17040548654;DMAP1_NCOR{1,2}_SMARC:2.02779701575;HLF:2.02508426661;FOXP3:1.95452028118;FOS_FOS{B,L1}_JUN{B,D}:1.81605959918;BACH2:1.80442102504;NFIL3:1.76600484738;NR1H4:1.61236023102;ELF1,2,4:1.5940092459;RUNX1..3:1.53444076353;NFKB1_REL_RELA:1.48795537917;ATF5_CREB3:1.48231838419;TLX2:1.44717221104;ATF4:1.39456500693;HMX1:1.36577954282;ATF6:1.33661549607;NR6A1:1.30664693297;HSF1,2:1.23907685764;TGIF1:1.23648042787;HIF1A:1.13638819053;ALX4:1.09857470182;TFCP2:1.03683055928;HBP1_HMGB_SSRP1_UBTF:0.99492090151;PDX1:0.959199394152;NFE2L1:0.953624406924;CREB1:0.858775908333;SPZ1:0.798030278199;BPTF:0.784772604631;ATF2:0.761676862813;ESRRA:0.722392599703;SMAD1..7,9:0.694414071621;MAFB:0.651962371421;HMGA1,2:0.616130821789;ZBTB16:0.604911525452;JUN:0.600675334255;FOX{D1,D2}:0.558578484628;GATA4:0.493895557281;FOX{F1,F2,J1}:0.4049533894;RXRA_VDR{dimer}:0.402319163205;PPARG:0.385942595518;NFATC1..3:0.341533404042;RBPJ:0.312607759161;FOXO1,3,4:0.25933010476;GLI1..3:0.224247079045;RFX2..5_RFXANK_RFXAP:0.200980463989;AHR_ARNT_ARNT2:0.184732254632;EN1,2:0.156595987245;NANOG:0.149867255394;CDX1,2,4:0.142388682476;SRF:0.129656853557;PAX3,7:0.113748500467;XBP1:0.102751571685;PITX1..3:0.101466704497;VSX1,2:0.100805536651;PRDM1:0.0472164493685;IKZF2:-0.0388823809539;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.0737912916906;RXR{A,B,G}:-0.0888419727827;MYB:-0.0912909554921;NKX3-2:-0.166409635742;ESR1:-0.197427890544;NFIX:-0.236026946067;MYFfamily:-0.267302914845;TFAP4:-0.305515193925;IKZF1:-0.328490199052;HES1:-0.337741967153;NKX6-1,2:-0.341925862482;FOXP1:-0.365709062843;FOXM1:-0.368903848869;OCT4_SOX2{dimer}:-0.411568325906;HNF4A_NR2F1,2:-0.416136340192;PAX1,9:-0.417664364139;ZNF238:-0.46484664159;TBP:-0.473888541555;REST:-0.511370186738;POU1F1:-0.524737360013;EGR1..3:-0.527619709755;HOX{A6,A7,B6,B7}:-0.530937904091;MZF1:-0.549544382772;MEF2{A,B,C,D}:-0.593009208664;PATZ1:-0.602313393229;PAX8:-0.606192109732;FOXD3:-0.622928378184;POU5F1:-0.663317625432;SOX2:-0.678927758186;TAL1_TCF{3,4,12}:-0.687383306047;NHLH1,2:-0.700355695995;FOXA2:-0.709573417798;TFAP2{A,C}:-0.716221656273;PRRX1,2:-0.741628157128;HOX{A5,B5}:-0.757327987361;MED-1{core}:-0.773636397934;HNF1A:-0.775280932958;PAX4:-0.813481086352;RREB1:-0.815038627607;ZNF148:-0.820011632364;ALX1:-0.825910515079;GATA6:-0.844200730734;CUX2:-0.844470068139;RFX1:-0.847812457197;POU2F1..3:-0.8794506669;MYOD1:-0.892500433011;POU6F1:-0.921798822496;TFAP2B:-0.995923144099;RXR{A,B,G}_{NR1H2,PPAR}dimers:-1.01260495355;TOPORS:-1.01847583709;NKX3-1:-1.02989063977;FOXL1:-1.03894744975;RORA:-1.06330727051;MTE{core}:-1.06602501991;SP1:-1.07310834692;NKX2-2,8:-1.09733109661;FOX{I1,J2}:-1.12818731374;TP53:-1.14047670604;MTF1:-1.14064499766;NR3C1:-1.15253760178;EBF1:-1.17791619046;MAZ:-1.17857715217;ZFP161:-1.19921116312;LMO2:-1.20917664664;MYBL2:-1.21855543128;ZBTB6:-1.22740589911;DBP:-1.22830893107;FOXQ1:-1.23986962275;SOX5:-1.24945202726;BREu{core}:-1.27085875759;PAX6:-1.28148618516;ZEB1:-1.29047442477;CRX:-1.32663908828;GTF2I:-1.33530789305;HOXA9_MEIS1:-1.33771337062;TEF:-1.350947929;GZF1:-1.35769839878;GCM1,2:-1.36678623815;KLF4:-1.38255225422;UFEwm:-1.38869945515;TBX4,5:-1.39805612943;XCPE1{core}:-1.40561884896;NKX2-3_NKX2-5:-1.41607365449;SNAI1..3:-1.42548186216;TLX1..3_NFIC{dimer}:-1.42830895858;GTF2A1,2:-1.45376541666;AIRE:-1.5159143334;TEAD1:-1.53364436257;E2F1..5:-1.54179016221;PAX5:-1.56236869029;TFDP1:-1.5709267597;ZIC1..3:-1.59607272448;ELK1,4_GABP{A,B1}:-1.60198189874;NR5A1,2:-1.65090567805;HAND1,2:-1.67172663285;HIC1:-1.67278614722;YY1:-1.73340872247;EVI1:-1.73353819749;SOX{8,9,10}:-1.73740659586;CDC5L:-1.84244406019;AR:-1.92992649852;NKX2-1,4:-1.95936928631;T:-1.96451154925;ONECUT1,2:-1.9826533829;bHLH_family:-1.98296191908;GFI1B:-1.98497963519;ADNP_IRX_SIX_ZHX:-2.0459249386;ZNF384:-2.05030329197;HOX{A4,D4}:-2.07756429774;ZNF423:-2.09421362714;NFY{A,B,C}:-2.24926668234;GFI1:-2.26652769318;NRF1:-2.35487193675;SOX17:-2.41418372761;POU3F1..4:-2.59000270507;LEF1_TCF7_TCF7L1,2:-2.72512046823;LHX3,4:-2.85962971112;PBX1:-2.87344375237;ZNF143:-2.8797071253;ARID5B:-3.14837698233 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11881-125C9;search_select_hide=table117:FF:11881-125C9 | |||
}} | }} |
Latest revision as of 18:26, 4 June 2020
Name: | CD14+ monocytes - treated with IFN + N-hexane, donor3 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13490 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13490
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13490
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.112 |
10 | 10 | 0.0238 |
100 | 100 | 0.813 |
101 | 101 | 0.845 |
102 | 102 | 0.586 |
103 | 103 | 0.244 |
104 | 104 | 0.622 |
105 | 105 | 0.269 |
106 | 106 | 3.16887e-4 |
107 | 107 | 0.218 |
108 | 108 | 0.992 |
109 | 109 | 0.191 |
11 | 11 | 0.14 |
110 | 110 | 0.177 |
111 | 111 | 0.0717 |
112 | 112 | 0.327 |
113 | 113 | 0.53 |
114 | 114 | 0.00884 |
115 | 115 | 0.18 |
116 | 116 | 0.865 |
117 | 117 | 0.0808 |
118 | 118 | 0.22 |
119 | 119 | 0.153 |
12 | 12 | 0.415 |
120 | 120 | 0.477 |
121 | 121 | 0.586 |
122 | 122 | 0.552 |
123 | 123 | 0.196 |
124 | 124 | 0.792 |
125 | 125 | 0.507 |
126 | 126 | 0.297 |
127 | 127 | 0.31 |
128 | 128 | 0.0324 |
129 | 129 | 0.426 |
13 | 13 | 0.171 |
130 | 130 | 0.143 |
131 | 131 | 0.411 |
132 | 132 | 0.113 |
133 | 133 | 0.908 |
134 | 134 | 0.469 |
135 | 135 | 0.406 |
136 | 136 | 0.913 |
137 | 137 | 0.0135 |
138 | 138 | 0.134 |
139 | 139 | 0.0663 |
14 | 14 | 0.442 |
140 | 140 | 0.311 |
141 | 141 | 0.192 |
142 | 142 | 0.298 |
143 | 143 | 0.0432 |
144 | 144 | 0.797 |
145 | 145 | 0.504 |
146 | 146 | 0.702 |
147 | 147 | 0.417 |
148 | 148 | 0.0127 |
149 | 149 | 0.768 |
15 | 15 | 0.144 |
150 | 150 | 0.453 |
151 | 151 | 0.256 |
152 | 152 | 0.0973 |
153 | 153 | 0.664 |
154 | 154 | 0.479 |
155 | 155 | 0.747 |
156 | 156 | 0.53 |
157 | 157 | 0.61 |
158 | 158 | 0.0981 |
159 | 159 | 0.808 |
16 | 16 | 0.34 |
160 | 160 | 0.46 |
161 | 161 | 0.499 |
162 | 162 | 0.308 |
163 | 163 | 0.287 |
164 | 164 | 0.207 |
165 | 165 | 0.0618 |
166 | 166 | 0.63 |
167 | 167 | 0.291 |
168 | 168 | 0.223 |
169 | 169 | 0.00743 |
17 | 17 | 0.23 |
18 | 18 | 0.178 |
19 | 19 | 0.265 |
2 | 2 | 0.92 |
20 | 20 | 0.389 |
21 | 21 | 0.396 |
22 | 22 | 0.197 |
23 | 23 | 0.031 |
24 | 24 | 0.224 |
25 | 25 | 0.354 |
26 | 26 | 0.0649 |
27 | 27 | 0.805 |
28 | 28 | 0.476 |
29 | 29 | 0.304 |
3 | 3 | 0.084 |
30 | 30 | 0.617 |
31 | 31 | 0.846 |
32 | 32 | 0.8 |
33 | 33 | 0.347 |
34 | 34 | 0.497 |
35 | 35 | 0.192 |
36 | 36 | 0.134 |
37 | 37 | 0.0687 |
38 | 38 | 0.467 |
39 | 39 | 0.786 |
4 | 4 | 0.894 |
40 | 40 | 0.247 |
41 | 41 | 0.0499 |
42 | 42 | 0.356 |
43 | 43 | 0.0392 |
44 | 44 | 0.655 |
45 | 45 | 0.771 |
46 | 46 | 0.162 |
47 | 47 | 0.449 |
48 | 48 | 0.42 |
49 | 49 | 0.123 |
5 | 5 | 0.175 |
50 | 50 | 0.95 |
51 | 51 | 0.343 |
52 | 52 | 0.245 |
53 | 53 | 0.352 |
54 | 54 | 0.283 |
55 | 55 | 0.358 |
56 | 56 | 0.685 |
57 | 57 | 0.844 |
58 | 58 | 0.11 |
59 | 59 | 0.183 |
6 | 6 | 0.716 |
60 | 60 | 0.0249 |
61 | 61 | 0.65 |
62 | 62 | 0.0354 |
63 | 63 | 0.442 |
64 | 64 | 0.489 |
65 | 65 | 0.237 |
66 | 66 | 0.267 |
67 | 67 | 0.478 |
68 | 68 | 0.825 |
69 | 69 | 0.605 |
7 | 7 | 0.304 |
70 | 70 | 0.0187 |
71 | 71 | 0.0517 |
72 | 72 | 0.115 |
73 | 73 | 0.105 |
74 | 74 | 0.125 |
75 | 75 | 0.114 |
76 | 76 | 0.382 |
77 | 77 | 0.401 |
78 | 78 | 0.105 |
79 | 79 | 0.0563 |
8 | 8 | 0.387 |
80 | 80 | 0.147 |
81 | 81 | 0.328 |
82 | 82 | 0.105 |
83 | 83 | 0.394 |
84 | 84 | 0.43 |
85 | 85 | 0.0171 |
86 | 86 | 0.0357 |
87 | 87 | 0.496 |
88 | 88 | 0.529 |
89 | 89 | 0.294 |
9 | 9 | 0.275 |
90 | 90 | 0.0783 |
91 | 91 | 0.333 |
92 | 92 | 0.175 |
93 | 93 | 0.176 |
94 | 94 | 0.049 |
95 | 95 | 0.455 |
96 | 96 | 0.318 |
97 | 97 | 0.768 |
98 | 98 | 0.075 |
99 | 99 | 0.122 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13490
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0011443 CD14-positive monocytes - treated with IFN + N-hexane sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000766 (myeloid leukocyte)
0000219 (motile cell)
0000325 (stuff accumulating cell)
0000473 (defensive cell)
0000234 (phagocyte)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0000255 (eukaryotic cell)
0000576 (monocyte)
0000860 (classical monocyte)
0002057 (CD14-positive, CD16-negative classical monocyte)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
0000350 (experimentally modified sample)
0000629 (IFN and N-hexane treatment sample)
0011443 (CD14-positive monocytes - treated with IFN + N-hexane sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)
CL:0002057 (CD14-positive, CD16-negative classical monocyte)